Receptor
PDB id Resolution Class Description Source Keywords
5IRR 2.04 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF SEPTIN GTPASE DOMAIN FROM CHLAMYDOMONAS REINHARDTII CHLAMYDOMONAS REINHARDTII SEPTIN GTPASE DOMAIN HYDROLASE
Ref.: FILAMENTS AND FINGERS: NOVEL STRUCTURAL ASPECTS OF SINGLE SEPTIN FROM CHLAMYDOMONAS REINHARDTII. J. BIOL. CHEM. V. 292 10899 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:401;
B:401;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
GSP B:402;
A:402;
Valid;
Valid;
none;
none;
Kd = 5.4 uM
539.246 C10 H16 N5 O13 P3 S c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5IRR 2.04 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF SEPTIN GTPASE DOMAIN FROM CHLAMYDOMONAS REINHARDTII CHLAMYDOMONAS REINHARDTII SEPTIN GTPASE DOMAIN HYDROLASE
Ref.: FILAMENTS AND FINGERS: NOVEL STRUCTURAL ASPECTS OF SINGLE SEPTIN FROM CHLAMYDOMONAS REINHARDTII. J. BIOL. CHEM. V. 292 10899 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 5IRR Kd = 5.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 5IRR Kd = 5.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 5IRR Kd = 5.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GSP; Similar ligands found: 132
No: Ligand ECFP6 Tc MDL keys Tc
1 GSP 1 1
2 GP3 0.897436 0.925
3 GTP 0.853659 0.948718
4 GNH 0.829268 0.936709
5 GDP 0.817073 0.948718
6 G1R 0.8 0.936709
7 GCP 0.77907 0.925
8 GNP 0.770115 0.925
9 GMV 0.767442 0.925
10 5GP 0.756098 0.935897
11 G 0.756098 0.935897
12 G2R 0.747253 0.91358
13 GKE 0.744681 0.91358
14 GDD 0.744681 0.91358
15 GDC 0.744681 0.91358
16 GPG 0.73913 0.91358
17 GTG 0.736842 0.891566
18 G3A 0.729167 0.925
19 G5P 0.721649 0.925
20 GDR 0.71875 0.91358
21 GFB 0.71875 0.91358
22 GAV 0.714286 0.987179
23 GP2 0.712644 0.91358
24 6CK 0.71134 0.891566
25 Y9Z 0.708333 0.860465
26 JB2 0.69697 0.91358
27 GKD 0.69697 0.91358
28 GDP MG 0.696629 0.878049
29 G2P 0.692308 0.91358
30 GDX 0.69 0.925
31 GPD 0.69 0.880952
32 GDP BEF 0.688889 0.857143
33 GCP G 0.677419 0.888889
34 ALF 5GP 0.67033 0.847059
35 0O2 0.666667 0.935897
36 GTP MG 0.666667 0.878049
37 BEF GDP 0.666667 0.847059
38 YGP 0.663265 0.858824
39 JB3 0.657143 0.902439
40 GDP ALF 0.645833 0.847059
41 GDP AF3 0.645833 0.847059
42 G G 0.642857 0.888889
43 GMP 0.641975 0.835443
44 G3D 0.638298 0.935897
45 NGD 0.635514 0.91358
46 2MD 0.633027 0.894118
47 CAG 0.630631 0.840909
48 G4P 0.625 0.935897
49 U2G 0.62037 0.891566
50 FEG 0.62037 0.83908
51 MGD 0.616071 0.894118
52 ZGP 0.614679 0.872093
53 CG2 0.609091 0.891566
54 TPG 0.598291 0.804348
55 3GP 0.595506 0.898734
56 GDP 7MG 0.590476 0.86747
57 GH3 0.581633 0.924051
58 MD1 0.581197 0.894118
59 PGD 0.581197 0.926829
60 2GP 0.577778 0.911392
61 DGT 0.561224 0.878049
62 DBG 0.558333 0.902439
63 G1G 0.550847 0.880952
64 SAP 0.547368 0.924051
65 AGS 0.547368 0.924051
66 FE9 0.546219 0.8
67 G4M 0.539062 0.840909
68 U A G G 0.538462 0.888889
69 G A A A 0.529915 0.878049
70 MGP 0.525253 0.91358
71 GPX 0.524272 0.898734
72 BGO 0.521739 0.879518
73 DGI 0.520408 0.878049
74 6G0 0.52 0.91358
75 I2C FE2 CMO CMO 0.516667 0.774194
76 IDP 0.515464 0.923077
77 GGM 0.508475 0.858824
78 G1R G1R 0.508065 0.879518
79 PGD O 0.504 0.875
80 G G U 0.5 0.888889
81 GTA 0.486726 0.891566
82 P2G 0.484536 0.839506
83 GPC 0.483607 0.83908
84 G C 0.483333 0.857143
85 P1G 0.474747 0.829268
86 DG 0.474227 0.865854
87 DGP 0.474227 0.865854
88 BA3 0.46875 0.85
89 AP5 0.463918 0.85
90 B4P 0.463918 0.85
91 IMP 0.463918 0.910256
92 G2Q 0.462963 0.91358
93 G G G RPC 0.459016 0.833333
94 APC G U 0.456 0.843373
95 U G A 0.452555 0.847059
96 ATP 0.45 0.873418
97 G G G C 0.448819 0.869048
98 A2D 0.447917 0.85
99 5FA 0.445545 0.873418
100 AQP 0.445545 0.873418
101 A G C C 0.445312 0.86747
102 G7M 0.444444 0.901235
103 G U34 0.442623 0.847059
104 01G 0.442478 0.860465
105 ITT 0.44 0.825
106 SGP 0.44 0.876543
107 G C C C 0.431818 0.879518
108 AN2 0.43 0.8625
109 DG DG 0.428571 0.825581
110 A4P 0.42623 0.829545
111 UCG 0.424242 0.86747
112 C2E 0.423077 0.875
113 PCG 0.423077 0.886076
114 35G 0.423077 0.886076
115 MGO 0.420561 0.823529
116 ADP 0.42 0.873418
117 ANP 0.419048 0.851852
118 5GP 5GP 0.419048 0.839506
119 ADQ 0.418182 0.829268
120 APR 0.417476 0.85
121 AR6 0.417476 0.85
122 7DT 0.417476 0.860759
123 A G U 0.414286 0.847059
124 AD9 0.413462 0.851852
125 UP5 0.413223 0.831325
126 A22 0.412844 0.8625
127 25L 0.412281 0.8625
128 M33 0.411765 0.839506
129 JBT 0.410405 0.783505
130 ACP 0.407767 0.851852
131 ACQ 0.40566 0.851852
132 A1R 0.405405 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5IRR; Ligand: GSP; Similar sites found: 442
This union binding pocket(no: 1) in the query (biounit: 5irr.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4LPS GDP 0.0000002617 0.52804 None
2 1ZUI SKM 0.000429 0.46774 None
3 3BFX A3P 0.001993 0.42754 1.35135
4 3TMK T5A 0.001204 0.4396 1.38889
5 1H65 GDP 0.00001807 0.5053 1.48148
6 2Q2Y ADP 0.0003326 0.47778 1.62338
7 2Q2Y MKR 0.0003933 0.4733 1.62338
8 1IWE IMP 0.009709 0.44457 1.62338
9 4ZNL BEF ADP 0.0001753 0.42315 1.82482
10 1YRB GDP 0.0000039 0.50144 1.9084
11 2J5V PCA 0.03778 0.41316 1.94805
12 3BOS CDP 0.0001332 0.42387 2.06612
13 5BQ5 ADP BEF 0.0001631 0.49055 2.1164
14 1TQ4 GDP 0.000003604 0.52763 2.27273
15 2VVG ADP 0.0000007159 0.43941 2.27273
16 1S3G AP5 0.001939 0.44352 2.30415
17 4NON GDP 0.000002033 0.55675 2.30769
18 2Z5F A3P 0.002628 0.41075 2.34899
19 1G3M PCQ 0.01295 0.40554 2.38095
20 1G3M A3P 0.01295 0.40554 2.38095
21 1W4R TTP 0.003925 0.41605 2.5641
22 3ZFD ANP 0.00000008984 0.55416 2.5974
23 5M04 GDP 0.000004646 0.46526 2.5974
24 1FNN ADP 0.0005121 0.43308 2.5974
25 1T5C ADP 0.000002867 0.427 2.5974
26 4YS0 ADP 0.0007394 0.42288 2.5974
27 1QF5 RPL 0.04094 0.41601 2.5974
28 1QF5 GDP 0.04094 0.41601 2.5974
29 2WIC GNP 0.007975 0.42667 2.62172
30 4HI0 GDP 0.000008975 0.51133 2.64151
31 2QZ4 ADP 0.00006089 0.45015 2.67176
32 1M2Z BOG 0.02195 0.41748 2.72374
33 4AG5 ADP 0.00001602 0.57397 2.92208
34 2XT3 ADP 0.000001051 0.44734 2.92208
35 2ZPA ADP 0.000247 0.44513 2.92208
36 1YTM ATP 0.0007554 0.4417 2.92208
37 3DZD ADP 0.0001532 0.44164 2.92208
38 5HR5 ADP 0.0002762 0.43689 2.92208
39 1OS1 ATP 0.001725 0.43288 2.92208
40 1OS1 PYR 0.001937 0.43218 2.92208
41 1XKV ATP 0.0002369 0.42823 2.92208
42 3CV2 OXL 0.02477 0.40768 2.92208
43 3W5J GDP 0.000002212 0.43083 2.94118
44 1D2N ANP 0.001576 0.41897 2.94118
45 2PL3 ADP 0.00009581 0.42025 2.9661
46 1L2T ATP 0.0009958 0.43647 2.97872
47 5H56 ADP 0.001081 0.44314 3.07692
48 5H56 TYD 0.001081 0.44314 3.07692
49 1VHT BA3 0.0003093 0.42229 3.21101
50 4ZG4 VO4 ADP 0.000002173 0.54621 3.24675
51 1F5N GNP 0.000009357 0.5263 3.24675
52 4PFO ADP 0.00009268 0.48195 3.24675
53 1DAR GDP 0.000008345 0.47078 3.24675
54 3COB ADP 0.00000226 0.44308 3.24675
55 1W5T ANP 0.0007237 0.43318 3.24675
56 1W5T ADP 0.0008976 0.4189 3.24675
57 4KBF AMP 0.0001745 0.41165 3.24675
58 3T5G GDP 0.000002483 0.50138 3.31492
59 1XTQ GDP 0.0000008663 0.56296 3.38983
60 1V8K ANP 0.000001202 0.49618 3.57143
61 1X6V ADP 0.0004507 0.45796 3.57143
62 1IN4 ADP 0.0003201 0.44089 3.57143
63 1NY5 ADP 0.0002344 0.43938 3.57143
64 1P72 ADP 0.00204 0.434 3.57143
65 1OXV ANP 0.00003591 0.42877 3.57143
66 4BFW ZVW 0.005004 0.42509 3.57143
67 2FAH GDP 0.0006069 0.4209 3.57143
68 4PJ3 ANP 0.001117 0.4099 3.57143
69 2VF7 ADP 0.0006886 0.40604 3.57143
70 1QF9 C5P 0.004627 0.42332 3.60825
71 1QF9 ADP 0.004627 0.42332 3.60825
72 1QF9 ALF 0.004627 0.42332 3.60825
73 4R98 GNH 0.00000003512 0.54223 3.69004
74 4D81 ADP 0.0001889 0.43755 3.88693
75 2DPY ADP 0.00002696 0.55633 3.8961
76 1G7S GDP 0.00002905 0.532 3.8961
77 3TK1 GDP 0.0000006059 0.48306 3.8961
78 4B47 GDP 0.000003359 0.47177 3.8961
79 2ZFI ADP 0.00001437 0.46128 3.8961
80 1F9V ADP 0.000007961 0.43958 3.8961
81 4Q1A 2XZ 0.0238 0.43803 3.92857
82 4Q1A UDP 0.0238 0.43803 3.92857
83 1NJF AGS 0.0004805 0.44592 4
84 1NJF ADP 0.0003682 0.43858 4
85 5L3V GDP 0.00001574 0.46898 4.01338
86 2VB6 ADP BEF 0.00003875 0.49376 4.02685
87 2GWH A3P 0.002618 0.4021 4.02685
88 2ZPT A3P 0.02407 0.40504 4.0678
89 3FB4 AP5 0.002248 0.44065 4.16667
90 2F5X ASP 0.02779 0.4015 4.16667
91 4X8O AP5 0.003114 0.4394 4.20561
92 2XTZ GSP 0.0000002444 0.59126 4.22078
93 4MKG AP5 0.00268 0.43723 4.22078
94 2ZR9 DTP 0.0001768 0.41512 4.22078
95 2C9O ADP 0.02999 0.40923 4.22078
96 1SVM ATP 0.016 0.40867 4.22078
97 3A1S GDP 0.00000491 0.48761 4.26357
98 5TIV A3P 0.01588 0.40537 4.34783
99 2CHG ANP 0.0004211 0.43149 4.42478
100 5L3R GCP 0.000005418 0.53194 4.43686
101 5X40 ACP 0.001686 0.42504 4.45205
102 3B5J 12D 0.0001485 0.40695 4.52675
103 3FVQ ATP 0.0004067 0.44311 4.54545
104 4HSE ADP 0.00004877 0.44181 4.54545
105 3FYH ADP 0.003497 0.41345 4.54545
106 2D7D ADP 0.0003192 0.41011 4.54545
107 3TBK ANP 0.0001885 0.40731 4.54545
108 3NHB ADP 0.00002551 0.41832 4.57516
109 1WF3 GNP 0.0000001765 0.59976 4.65116
110 4P32 ADP 0.003156 0.41183 4.81928
111 1FP6 ADP 0.00008072 0.45072 4.84429
112 2RGX AP5 0.003086 0.4366 4.85437
113 1TAD ALF 0.00000004739 0.62908 4.87013
114 1TAD GDP 0.00000004739 0.62908 4.87013
115 4RD0 GDP 0.0000000449 0.61387 4.87013
116 1FQJ GDP 0.000001371 0.5546 4.87013
117 1FQK GDP 0.000002734 0.54203 4.87013
118 2B8W ALF 5GP 0.000007403 0.52623 4.87013
119 4IEE AGS 0.0002497 0.49995 4.87013
120 5KSZ GCP 0.00002502 0.47047 4.87013
121 3E70 GDP 0.00002648 0.45376 4.87013
122 1FQJ ALF 0.000001383 0.45161 4.87013
123 5LB3 ADP 0.00001347 0.44709 4.87013
124 1GOJ ADP 0.0000003182 0.44631 4.87013
125 2BEK ATP 0.002016 0.44049 4.87013
126 3QKT ANP 0.001135 0.43408 4.87013
127 2IS6 ADP 0.00006271 0.42836 4.87013
128 5GJC ATP 0.00008499 0.42736 4.87013
129 1FQK ALF 0.00000756 0.41736 4.87013
130 4QOS ADP 0.0002157 0.48491 4.90566
131 2C04 GCP 0.0003134 0.43893 5.05051
132 1G6H ADP 0.000008403 0.40682 5.05837
133 2A5F GTP 0.00000001221 0.64354 5.14286
134 4WZ6 ATP 0.00001526 0.42695 5.17241
135 2ODE ALF GDP 0.00000002846 0.63861 5.19481
136 4H1V GNP 0.000003574 0.51308 5.19481
137 3ZQ6 ADP ALF 0.0001014 0.48221 5.19481
138 1KK1 GNP 0.0000029 0.47381 5.19481
139 1E2K TMC 0.001083 0.45484 5.19481
140 5TSH ANP 0.00001801 0.44751 5.19481
141 5TSH ADP 0.00001268 0.42923 5.19481
142 2OFW ADX 0.0007372 0.46113 5.28846
143 2GDJ ANP 0.0004089 0.40676 5.30303
144 2HF9 GSP 0.00002825 0.50383 5.30973
145 1DAK DPU 0.02215 0.42367 5.35714
146 1DAK ADP 0.02215 0.42367 5.35714
147 3A4M ADP 0.000004224 0.45054 5.38462
148 1JI0 ATP 0.00004837 0.54332 5.41667
149 1UKZ ADP 0.004912 0.4186 5.41872
150 1AZT GSP 0.00000003666 0.63388 5.51948
151 2RCN GDP 0.0000001753 0.51932 5.51948
152 1JWY GDP 0.000004233 0.50339 5.51948
153 1JWY ADP 0.000007788 0.47141 5.51948
154 3EC1 GDP 0.00001374 0.46717 5.51948
155 1NHX FTB 0.003061 0.43877 5.51948
156 1NHX PEP 0.003314 0.43622 5.51948
157 2GMV UN8 0.001474 0.43427 5.51948
158 2GMV PEP 0.00291 0.42453 5.51948
159 4GOX A3P 0.004744 0.40618 5.51948
160 5L3W GDP 0.0000582 0.45048 5.55556
161 1PUJ GNP 0.00000001168 0.59588 5.67376
162 5L3S GNP 0.000006121 0.52971 5.74324
163 4NCN GTP 0.00000006394 0.61041 5.84416
164 3WXM GTP 0.00000008856 0.60994 5.84416
165 2BVN GNP 0.0000006658 0.532 5.84416
166 1D8T GDP 0.000001583 0.49376 5.84416
167 1SKQ GDP 0.000001333 0.48571 5.84416
168 1IHU ADP 0.0003174 0.45547 5.84416
169 1IHU AF3 0.0003185 0.45336 5.84416
170 2Y65 ADP 0.00000491 0.43151 5.84416
171 1NST A3P 0.0014 0.41177 5.84416
172 5UWP GNP 0.00000002346 0.63971 5.90717
173 5UWU GNP 0.00000002171 0.63854 5.90717
174 5UWR GNP 0.00000002182 0.63844 5.90717
175 5DIF GNP 0.0000000226 0.63779 5.90717
176 5UWO GNP 0.00000002281 0.63761 5.90717
177 5DHF GNP 0.00000002315 0.63735 5.90717
178 5UWI GNP 0.00000002322 0.63729 5.90717
179 5UWT GNP 0.00000002379 0.63684 5.90717
180 5UWH GNP 0.00000002383 0.63681 5.90717
181 5DI9 GNP 0.00000002907 0.63572 5.90717
182 5UWS GNP 0.00000003465 0.63245 5.90717
183 5UWQ GNP 0.00000002409 0.57787 5.90717
184 5UWJ GNP 0.00000002505 0.57731 5.90717
185 1G3Q ADP 0.0003944 0.41175 5.90717
186 2GCO GNP 0.00000004144 0.58529 5.97015
187 2GCN GDP 0.000001341 0.55238 5.97015
188 3DEF GDP 0.00000543 0.49827 6.10687
189 1Z83 AP5 0.0037 0.42399 6.12245
190 2PEZ DAT 0.0005491 0.45885 6.14525
191 2PEZ GGZ 0.0005491 0.45885 6.14525
192 2C78 GNP 0.00000002489 0.62454 6.16883
193 2C77 GNP 0.00000001458 0.62451 6.16883
194 4TTQ ATP 0.00006372 0.43157 6.16883
195 4RLQ 3SK 0.02151 0.40728 6.16883
196 1OW3 GDP 0.0000002761 0.55442 6.21762
197 4YMU ATP 0.00002537 0.43287 6.25
198 5KSP GDP 0.00001811 0.46687 6.31579
199 3GJ0 GDP 0.0000006846 0.61835 6.33484
200 3GJ3 GDP 0.000001414 0.49048 6.33484
201 1GWN GTP 0.00000001009 0.63165 6.34146
202 5KUT GDP 0.0000004464 0.52031 6.34921
203 1G7C 5GP 0.00002841 0.44654 6.38298
204 3M1I GTP 0.00000003538 0.6295 6.39269
205 2XTN GTP 0.000002518 0.54353 6.41026
206 4HAT GNP 0.00000002797 0.63643 6.48148
207 1IBR GNP 0.00000003231 0.63118 6.48148
208 5HPY GDP 0.0000003281 0.55167 6.48649
209 4D0N GDP 0.0000001241 0.52172 6.48649
210 4FRZ ADP 0.000004237 0.44676 6.49351
211 1YQT ADP 0.00003082 0.4119 6.49351
212 1KMQ GNP 0.00000001059 0.64314 6.52174
213 2AWN ADP 0.0000005695 0.42083 6.56168
214 1CS4 GSP 0.00000009177 0.54605 6.60377
215 2J0V GDP 0.0000007903 0.50827 6.60377
216 3Q72 GNP 0.00000005652 0.5227 6.62651
217 2A9K GDP 0.000004705 0.50733 6.72646
218 1TX4 ALF GDP 0.00000001447 0.62059 6.77966
219 4LC1 GDP 0.000000936 0.4941 6.81818
220 4U00 ADP 0.000006388 0.41029 6.96721
221 2GJ8 ALF GDP 0.000000598 0.52589 6.97674
222 1Q20 A3P 0.008906 0.40725 7.02341
223 1Q20 PLO 0.008906 0.40725 7.02341
224 1M7B GTP 0.00000001006 0.63164 7.06522
225 1LVG ADP 0.0000119 0.43743 7.07071
226 1U8Z GDP 0.000001131 0.5581 7.14286
227 5I0H ADP BEF 0.000001597 0.54139 7.14286
228 4WZA ACP 0.00006819 0.52817 7.14286
229 4WZA ADP 0.00007613 0.52593 7.14286
230 4R43 GDP 0.0005154 0.47825 7.14286
231 4FCW ADP 0.0004512 0.41796 7.14286
232 4LJ9 ACP 0.0006687 0.40499 7.14286
233 2WHX ADP 0.00007093 0.40236 7.14286
234 1SVI GDP 0.0000005749 0.49512 7.17949
235 1RJ9 GCP 0.00007212 0.51129 7.23684
236 1YZG GDP 0.0000006861 0.51523 7.26257
237 2BCG GDP 0.000001066 0.5405 7.28155
238 3H86 AP5 0.01168 0.40324 7.29167
239 4CVN ADP 0.000002864 0.60627 7.29927
240 1X1R GDP 0.000001791 0.55689 7.30337
241 4MKF AP5 0.00207 0.44335 7.37327
242 4BQS K2Q 0.00143 0.44468 7.38636
243 4BQS ADP 0.00143 0.44468 7.38636
244 4DSU GDP 0.000001515 0.55999 7.40741
245 5UQW GDP 0.000001425 0.55639 7.40741
246 1ION ADP 0.000472 0.41469 7.40741
247 3P4X ADP 0.000004998 0.46467 7.46753
248 2XAU ADP 0.0007075 0.41119 7.46753
249 2BME GNP 0.000000004624 0.66429 7.52688
250 2F9L GDP 0.000002339 0.54487 7.53769
251 4WOP CTP 0.00003294 0.48784 7.55556
252 5TAR GDP 0.000002088 0.5709 7.56757
253 5TB5 GDP 0.00000183 0.5047 7.56757
254 1B7T ADP 0.0000234 0.46468 7.69231
255 3KTA AP5 0.0004697 0.42323 7.69231
256 2IYL GDP 0.00001421 0.45578 7.74648
257 3DKP ADP 0.0000853 0.43075 7.7551
258 4HDO GNP 0.00000002692 0.63456 7.78443
259 1D2E GDP 0.000002314 0.51212 7.79221
260 3FWY ADP 0.0001209 0.4537 7.79221
261 3DC4 ADP 0.000006056 0.45026 7.79221
262 2CJW GDP 0.00000003591 0.5433 7.8125
263 1OIX GDP 0.00000004563 0.62215 7.8534
264 1OIV GDP 0.000001153 0.5627 7.8534
265 4U5X GNP 0.0000001221 0.57708 7.86517
266 1WA5 GTP 0.00000006436 0.62797 7.95455
267 1ZD9 GDP 0.00002071 0.48979 7.97872
268 2KIN ADP 0.000002783 0.42527 7.98319
269 1D5C GDP 0.000001536 0.52657 8.02469
270 3VX3 ADP 0.0004185 0.43714 8.06452
271 2C5L GTP 0.00000001423 0.64635 8.09249
272 1YZN GNP 0.00000001008 0.65273 8.10811
273 3RWO GDP 0.0000005429 0.57657 8.10811
274 1Z6T ADP 0.0001706 0.44415 8.11688
275 1R6B ADP 0.0002063 0.42436 8.11688
276 3GJ8 GDP 0.000001518 0.49797 8.1448
277 3GJ7 GDP 0.0000008105 0.49748 8.1448
278 3GJ5 GDP 0.00000179 0.49593 8.1448
279 3GJ4 GDP 0.000001003 0.49551 8.1448
280 3H4S ADP 0.000001699 0.44453 8.14815
281 4K81 GTP 0.000000008556 0.65846 8.18713
282 2FFQ GSP 0.00000001085 0.65137 8.18713
283 1UPT GTP 0.00000001694 0.6315 8.18713
284 5XCO GDP 0.000001069 0.52293 8.18713
285 1YZQ GNP 0.00000001026 0.65241 8.23529
286 1JJV ATP 0.000007975 0.42834 8.25243
287 1NRJ GTP 0.00000005072 0.60305 8.25688
288 5O2T GSP 0.00000003231 0.63117 8.28402
289 1ZIN AP5 0.002123 0.44176 8.29493
290 4NU0 AP5 0.002442 0.43679 8.29493
291 3IIJ ADP 0.00003556 0.43862 8.33333
292 1LFD GNP 0.00000001347 0.64461 8.38323
293 1KAO GDP 0.000003171 0.5142 8.38323
294 3DDC GNP 0.00000001851 0.64148 8.43373
295 2UZI GTP 0.0000000167 0.64065 8.43373
296 1NVV GNP 0.00000002615 0.63509 8.43373
297 1NVU GTP 0.00000004592 0.62467 8.43373
298 1O3Y GTP 0.0000000435 0.61742 8.43373
299 1J2J GTP 0.00000003022 0.60812 8.43373
300 1CLU DBG 0.000001518 0.58551 8.43373
301 1WQ1 GDP 0.000001077 0.559 8.43373
302 1WQ1 AF3 0.000005887 0.42414 8.43373
303 1SVK ALF GDP 0.00000002517 0.64332 8.44156
304 1BH2 GSP 0.00000005502 0.62629 8.44156
305 1Y3A GDP 0.00001352 0.51292 8.44156
306 2OM2 GDP 0.00004474 0.49392 8.44156
307 1GP2 GDP 0.00004603 0.48047 8.4507
308 3QBT GNP 0.000000002486 0.62487 8.62069
309 2HT6 GDP 0.0000001355 0.51446 8.62069
310 1KK8 BEF ADP 0.00001593 0.48592 8.63309
311 1GUA GNP 0.00000002469 0.57697 8.64198
312 3KUD GDP 0.000000343 0.5687 8.64198
313 4C4P GNP 0.00000001647 0.64364 8.67052
314 2ZEJ GDP 0.00001195 0.52177 8.69565
315 4OI4 ATP 0.0007111 0.44077 8.69565
316 2WKQ GTP 0.00000003598 0.62088 8.76623
317 1R2Q GNP 0.0000000008813 0.71621 8.82353
318 1G16 GDP 0.000002969 0.538 8.82353
319 1ZC3 GNP 0.000000008242 0.65645 8.84956
320 3MJH GTP 0.000000001785 0.68181 8.92857
321 1Z0F GDP 0.0000005134 0.5141 8.93855
322 1R4A GNP 0.000000004278 0.66275 9.09091
323 2BIF SIN 0.00312 0.4374 9.09091
324 2BIF ANP 0.00183 0.4374 9.09091
325 1BG2 ADP 0.000001512 0.43006 9.09091
326 4M9Q GNP 0.00000002878 0.62192 9.2511
327 2HV8 GTP 0.00000002091 0.63651 9.375
328 5IRC GDP 0.0000004997 0.52707 9.45274
329 5KDO GDP 0.00002869 0.49099 9.45946
330 1YVD GNP 0.000000002851 0.67319 9.46746
331 1M7G ADX 0.001461 0.43892 9.47867
332 1M7G ADP 0.001495 0.43556 9.47867
333 1M7G AV2 0.00003497 0.43303 9.47867
334 1Z2A GDP 0.000008713 0.50888 9.52381
335 4BAS GNP 0.000000002957 0.6631 9.54774
336 1GOT GDP 0.0000701 0.48077 9.58904
337 1MR3 G3D 0.0000006228 0.51582 9.94475
338 1SQ5 ADP 0.00007317 0.43808 10.0649
339 1F2U ATP 0.002277 0.42462 10.0671
340 1VG8 GNP 0.000000005346 0.66446 10.1449
341 1VG0 GDP 0.000001139 0.52343 10.1449
342 1ZJ6 G3D 0.00939 0.40742 10.1604
343 1S8F GDP 0.000311 0.49641 10.1695
344 3KJI ADP 0.006491 0.41897 10.2362
345 4DCT GDP 0.0000007123 0.50915 10.3896
346 2QEN ADP 0.0001153 0.45599 10.3896
347 1KY3 GDP 0.0000007121 0.52889 10.4396
348 1EK0 GNP 0.000000002763 0.67377 10.5882
349 2HCJ GDP 0.000001822 0.47968 10.8108
350 2A5J GDP 0.0000004492 0.60938 10.9948
351 5BXQ GDP 0.000001402 0.50038 11.0236
352 4IDN GNP 0.00002327 0.50072 11.039
353 2V7Q ATP 0.00007214 0.44394 11.039
354 1W0J ADP 0.000125 0.44256 11.039
355 2CK3 ADP 0.0008145 0.4383 11.039
356 1W0J ADP BEF 0.0004401 0.43641 11.039
357 2CK3 ANP 0.0004588 0.43549 11.039
358 2V7Q ADP 0.0001026 0.42572 11.039
359 2ZE7 DST 0.007493 0.40254 11.0672
360 2ZE7 AMP 0.006906 0.40254 11.0672
361 3BFV ADP 0.0000333 0.44146 11.0701
362 5CK5 GDP 0.0000003225 0.49617 11.0759
363 1F6B GDP 0.00004118 0.4551 11.1111
364 3Q85 GNP 0.0000002088 0.51937 11.2426
365 1VG9 GDP 0.0000003121 0.52465 11.3514
366 1VG1 GDP 0.0000004468 0.52001 11.3514
367 3AB3 GDP 0.00001909 0.49795 11.3636
368 2JLR ANP 0.0003527 0.42636 11.3636
369 5HCN GCP 0.000002246 0.49253 11.4943
370 2QG6 NMN 0.0008649 0.44419 11.5578
371 1M2O GNP 0.0000002554 0.59045 11.5789
372 3SBD GNP 0.00000002511 0.63314 11.7647
373 3RAB GNP 0.000000005238 0.662 11.8343
374 2W58 ADP 0.0000005332 0.42961 11.8812
375 1Z0A GDP 0.0000008138 0.51857 12.069
376 2FH5 GTP 0.00000001297 0.62668 12.1495
377 3CX8 GSP 0.00000005347 0.62683 12.3377
378 3RLF ANP 0.0007003 0.44105 12.5
379 2IXE ATP 0.0007526 0.4378 12.5461
380 4PX9 ADP 0.00006972 0.42301 12.6712
381 4KFU ACP 0.00001195 0.43032 12.7358
382 1CXZ GSP 0.000000005414 0.65216 12.7907
383 1NF3 GNP 0.00000006141 0.61668 12.8205
384 5FG3 GDP 0.000003905 0.46939 12.987
385 1E96 GTP 0.00000004909 0.62081 13.0208
386 1DS6 GDP 0.0000005007 0.50557 13.0208
387 1I4D GDP 0.0000008655 0.49038 13.0208
388 1A4R GDP 0.0000008228 0.54558 13.089
389 1GRN GDP 0.0000006227 0.54183 13.089
390 1A4R GNH 0.0000008802 0.53629 13.089
391 2NGR GDP 0.0000001514 0.53366 13.089
392 4ITR GDP 0.000003749 0.51806 13.089
393 2NGR AF3 0.00001896 0.43916 13.089
394 1GRN AF3 0.00003349 0.43076 13.089
395 1FZQ GDP 0.000004973 0.47244 13.2597
396 2G77 GDP 0.00000009591 0.57286 13.3117
397 2G77 AF3 0.000001001 0.45907 13.3117
398 1MH1 GNP 0.00000003844 0.62796 13.4409
399 4QM7 GTP 0.00004417 0.43717 13.4503
400 2W2X GSP 0.000000008195 0.63443 13.5135
401 1G4U GDP 0.000004361 0.51542 13.587
402 4V0K GDP 0.0000228 0.50564 13.6095
403 1JJ7 ADP 0.000007329 0.40904 13.8462
404 3B7G ANP 0.00002704 0.4547 13.913
405 2FJU GSP 0.00000003718 0.60808 14.0449
406 1HE1 GDP 0.000004515 0.53629 14.2045
407 1HE1 AF3 0.0002905 0.50339 14.2045
408 2D7C GTP 0.000000004827 0.6635 14.2857
409 2QTV GNP 0.0000006231 0.57154 14.2857
410 5N69 ADP 0.00001435 0.47869 15.5844
411 1Z08 GNP 0.000003476 0.53766 15.8824
412 1TU3 GNP 0.000000005953 0.65964 16.4557
413 1MKY GDP 0.0000001949 0.5204 16.5584
414 3PQC GDP 0.000001827 0.50569 16.9231
415 2WJG GDP 0.00000006557 0.53782 17.0213
416 3T12 GDP ALF 0.000000009382 0.6422 17.6768
417 3T1O GDP 0.000001249 0.5131 17.6768
418 1KO8 6PG 0.0002944 0.44231 18.2857
419 3REF GDP 0.0000008654 0.56031 18.5567
420 3BC1 GNP 0.000000004901 0.66322 18.6441
421 3ZS9 ADP ALF 0.0003589 0.45883 18.6441
422 2WOJ ADP ALF 0.0003837 0.45759 18.6441
423 4XVU ATP 0.000305 0.45619 18.6441
424 4XTR ATP 0.0003128 0.45573 18.6441
425 4XTR ADP 0.0002467 0.44557 18.6441
426 1Z0K GTP 0.00000001035 0.64356 18.8406
427 2WJH GDP 0.0000001231 0.53875 19.2771
428 2WJH FLC 0.00000113 0.51326 19.2771
429 1KSH GDP 0.00000000996 0.63122 19.3548
430 4DID GDP 0.0000005917 0.51238 19.7368
431 1Z06 GNP 0.00000002341 0.63163 20.1058
432 2QN6 GDP 0.0000002976 0.50101 20.4301
433 1S9D GDP 0.000003204 0.5775 21.9512
434 1RE0 GDP 0.000004251 0.47236 21.9512
435 5UFQ GNP 0.00000102 0.56496 22.9508
436 1Z0J GTP 0.0000000019 0.6836 23.5294
437 5UWW GNP 0.00000002449 0.6363 23.8095
438 3QF7 ANP 0.001124 0.41952 24
439 3ZIA ATP 0.0000977 0.43129 25.3968
440 3ZIA ADP 0.0002977 0.42904 25.3968
441 3UIE ANP 0.0000419 0.45324 25.5
442 1RYH GNP 0.0000000296 0.56865 31.0345
Pocket No.: 2; Query (leader) PDB : 5IRR; Ligand: GSP; Similar sites found: 12
This union binding pocket(no: 2) in the query (biounit: 5irr.bio2) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4GBM A3P 0.00724 0.40159 2.27273
2 1VKJ A3P 0.006003 0.40156 2.45614
3 1I1N SAH 0.01137 0.40052 2.65487
4 5BYK OAQ 0.01669 0.4034 2.7027
5 5BYK A3P 0.01669 0.4034 2.7027
6 2PZM UDP 0.02571 0.40019 4.22078
7 2PZM NAD 0.02571 0.40019 4.22078
8 1UJ2 ADP 0.03068 0.40403 6.74603
9 2I4I AMP 0.003193 0.40547 6.81818
10 4TMK T5A 0.01263 0.4035 10.7981
11 3IUY AMP 0.001153 0.40183 28.0702
12 4QRH 0O2 0.005287 0.4039 28.5714
Feedback