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Receptor
PDB id Resolution Class Description Source Keywords
5IXJ 1.54 Å EC: 4.2.1.20 TRYPTOPHAN SYNTHASE BETA-SUBUNIT FROM PYROCOCCUS FURIOSUS WI THREONINE NON-COVALENTLY BOUND IN THE ACTIVE SITE PYROCOCCUS FURIOSUS (STRAIN ATCC 435873638 / JCM 8422 / VC1) SUBSTRATE ANALOG LYASE PLP FOLD-TYPE II
Ref.: SYNTHESIS OF BETA-BRANCHED TRYPTOPHAN ANALOGUES USI ENGINEERED SUBUNIT OF TRYPTOPHAN SYNTHASE. J.AM.CHEM.SOC. V. 138 8388 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NA B:402;
C:402;
D:402;
A:402;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
22.99 Na [Na+]
THR D:401;
A:401;
B:401;
C:401;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
119.119 C4 H9 N O3 C[C@H...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6AMI 1.97 Å EC: 4.2.1.20 ENGINEERED TRYPTOPHAN SYNTHASE B-SUBUNIT FROM PYROCOCCUS FUR PFTRPB4D11 WITH TRP NON-COVALENTLY BOUND PYROCOCCUS FURIOSUS (STRAIN ATCC 435873638 / JCM 8422 / VC1) PLP TYPE II TRYPTOPHAN SYNTHASE ENGINEERED ALLOSTERY BIOPROTEIN
Ref.: DIRECTED EVOLUTION MIMICS ALLOSTERIC ACTIVATION BY TUNING OF THE CONFORMATIONAL ENSEMBLE. J. AM. CHEM. SOC. V. 140 7256 2018
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 6AMI ic50 = 1400 uM TRP C11 H12 N2 O2 c1ccc2c(c1....
2 5DW3 - TRP C11 H12 N2 O2 c1ccc2c(c1....
3 6AM9 - 0JO C11 H13 N2 O7 P Cc1c(c(c(c....
4 5T6M - 78U C12 H14 N2 O2 C[C@@H](c1....
5 6AMH - PLS C11 H17 N2 O8 P Cc1c(c(c(c....
6 5DW0 - PLS C11 H17 N2 O8 P Cc1c(c(c(c....
7 5IXJ - THR C4 H9 N O3 C[C@H]([C@....
8 6CUT - FEJ C14 H21 N2 O8 P Cc1c(c(c(c....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 6AMI ic50 = 1400 uM TRP C11 H12 N2 O2 c1ccc2c(c1....
2 5DW3 - TRP C11 H12 N2 O2 c1ccc2c(c1....
3 6AM9 - 0JO C11 H13 N2 O7 P Cc1c(c(c(c....
4 5T6M - 78U C12 H14 N2 O2 C[C@@H](c1....
5 6AMH - PLS C11 H17 N2 O8 P Cc1c(c(c(c....
6 5DW0 - PLS C11 H17 N2 O8 P Cc1c(c(c(c....
7 5IXJ - THR C4 H9 N O3 C[C@H]([C@....
8 6CUT - FEJ C14 H21 N2 O8 P Cc1c(c(c(c....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 6AMI ic50 = 1400 uM TRP C11 H12 N2 O2 c1ccc2c(c1....
2 5DW3 - TRP C11 H12 N2 O2 c1ccc2c(c1....
3 6AM9 - 0JO C11 H13 N2 O7 P Cc1c(c(c(c....
4 5T6M - 78U C12 H14 N2 O2 C[C@@H](c1....
5 6AMH - PLS C11 H17 N2 O8 P Cc1c(c(c(c....
6 5DW0 - PLS C11 H17 N2 O8 P Cc1c(c(c(c....
7 5IXJ - THR C4 H9 N O3 C[C@H]([C@....
8 6CUT - FEJ C14 H21 N2 O8 P Cc1c(c(c(c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: THR; Similar ligands found: 13
No: Ligand ECFP6 Tc MDL keys Tc
1 THR 1 1
2 ALO 1 1
3 VAL 0.65 0.714286
4 DAL 0.578947 0.789474
5 ALA 0.578947 0.789474
6 VAH 0.541667 0.76
7 ILE 0.541667 0.6
8 HGY 0.526316 0.625
9 AHB 0.5 0.6
10 AKB 0.434783 0.857143
11 DBB 0.434783 0.625
12 ABA 0.434783 0.625
13 LFC 0.407407 0.619048
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6AMI; Ligand: TRP; Similar sites found with APoc: 297
This union binding pocket(no: 1) in the query (biounit: 6ami.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 1LNX URI None
2 2D7I NGA 1.26263
3 2WQN ADP 1.29032
4 3R7F CP 1.31579
5 3SHR CMP 1.33779
6 5XCZ GLC BGC 1.39665
7 4I54 1C1 1.41643
8 3V0H I3P 1.47493
9 6F8N NAG NAG 1.51515
10 1KKR 2AS 1.51515
11 3NZ1 3NY 1.51515
12 3I27 SID 1.5625
13 3FXU TSU 1.63934
14 2NSX IFM 1.76768
15 1E5Q SHR 1.76768
16 2WME NAP 1.76768
17 5OSW AE4 1.76768
18 6I6X H6B 1.76768
19 4M00 SUC 1.76768
20 3KC1 2T6 1.78042
21 4Y85 499 1.80723
22 3TK1 GDP 1.81818
23 4LAM 5CU 1.8617
24 6CAM BGC 1.9774
25 5M8T 0TR 2.0202
26 6FRN FMN 2.0202
27 3OBT SLB 2.0202
28 1K0E TRP 2.0202
29 5GMH RX8 2.0202
30 5AOA PPI 2.0979
31 5EYW PGA 2.27273
32 4N82 FMN 2.27273
33 4IP7 FBP 2.27273
34 3N6M GTP 2.27273
35 2O2C G6Q 2.27273
36 3TTM PUT 2.31214
37 4IJ6 SEP 2.36967
38 3T5M AMP 2.38095
39 3THR C2F 2.38908
40 3VOI RCB 2.41287
41 3JU6 ARG 2.43243
42 2IVD ACJ 2.52525
43 4ZZE GLC GLC GLC 2.52525
44 4WXJ GLU 2.60223
45 2I4O ATP 2.62009
46 5KBE IPH 2.62009
47 3MAN BMA BMA MAN 2.64901
48 4NAE 1GP 2.66667
49 4BT5 23B 2.72374
50 6GN6 GLC 2.77778
51 5A2Z GTP 2.77778
52 5WXU FLC 2.77778
53 4M3P HCS 2.77778
54 2OG2 MLI 2.78552
55 1VAY AZA 2.78746
56 5VJE GOS 2.7933
57 3RY9 1CA 2.8
58 1PFK ADP 2.8125
59 3FYP PEP 2.85714
60 4GK9 MAN BMA MAN MAN MAN 2.86738
61 1A99 PUT 2.90698
62 1TZD ADP 2.90909
63 5V8E CIT 2.91262
64 1CZR FMN 2.95858
65 1YBH P22 3.0303
66 2CJA ATP 3.0303
67 3WVR AMP 3.0303
68 6F90 MVL 3.0303
69 1GPM AMP 3.0303
70 4DDY DN6 3.04183
71 1W8S FBP 3.04183
72 3W6X HZP 3.05677
73 4IJP 1EH 3.07263
74 1BXG HCI 3.08989
75 1GOJ ADP 3.09859
76 4NBU CAA 3.2
77 4AF0 IMP 3.28283
78 4ZLA BES 3.28283
79 1T9D PYD 3.28283
80 3UG4 AHR 3.28283
81 5ZQS BXP 3.28283
82 1T9D P22 3.28283
83 5ZXD ATP 3.2967
84 1X9I G6Q 3.31126
85 4IXH IMP 3.3241
86 4E70 N7I 3.35052
87 1H74 ILE 3.37838
88 1LVW TYD 3.38983
89 2C6Q IMP 3.4188
90 5V3D FCN 3.44828
91 3UCJ AZM 3.52423
92 3BK2 U5P 3.53535
93 5JOX EDG 3.53535
94 5LQ8 GB 3.5461
95 3KVY URA 3.55987
96 5W75 SUC 3.57143
97 5KBF CMP 3.65448
98 3N29 GOL 3.78788
99 2POC UD1 3.81471
100 2POC BG6 3.81471
101 3DUV KDO 3.81679
102 3FGZ BEF 3.90625
103 1DQN IMU 3.91304
104 2AWN ADP 3.93701
105 6BXL SAM 3.96825
106 6GIU L69 3.97112
107 2D2F ADP 4
108 5CXX FER 4
109 1LSH PLD 4.0404
110 2YPI PGA 4.04858
111 3DER ALA LYS 4.05797
112 2BES RES 4.06977
113 1GT6 OLA 4.08922
114 1YRX FMN 4.13223
115 4DOL PLM 4.14747
116 4WOH 4NP 4.21687
117 5EXK MET 4.22961
118 4RL4 PPV 4.24528
119 5O4F 8VE 4.26357
120 6MDE MEV 4.29043
121 3VSV XYP 4.29293
122 1LFW AEP 4.29293
123 1TRD PGH 4.4
124 1NKI PPF 4.44444
125 1M5W DXP 4.52675
126 4LIK CIT 4.59184
127 5D2H AKG 4.59364
128 3UWV 2PG 4.5977
129 5YSI NCA 4.60526
130 2ZX2 RAM 4.61538
131 1XS1 DUT 4.66321
132 5Y02 MXN 4.6729
133 2HIM ASN 4.7486
134 1G6H ADP 4.79798
135 5ZFJ 9BF 4.84582
136 2X7I CIT 4.87013
137 2WPB ZZI 4.93421
138 2JK0 ASP 5.05051
139 2HXW FLC 5.06329
140 5GJO PLP 5.07614
141 2IU8 PLM 5.08021
142 2F5X ASP 5.12821
143 1FWV SGA MAG FUC 5.22388
144 1XX6 ADP 5.2356
145 1LYX PGA 5.24194
146 2FJK 13P 5.2459
147 4WOE 3S5 5.30303
148 4XZ3 ACP 5.30303
149 1Q8S MAN MMA 5.30303
150 1Q8Q MAN MMA 5.30303
151 2AL2 PEP 5.30303
152 1EWK GLU 5.30612
153 4ZXA H8N 5.30973
154 2QV7 ADP 5.34125
155 4JWX 1N4 5.35714
156 1O5O U5P 5.42986
157 3UIE ANP 5.5
158 4KCT FDP 5.55556
159 3B6C SDN 5.55556
160 5UY8 AMZ 5.55556
161 1AG9 FMN 5.71429
162 3Q8U ADP 5.73248
163 3RGQ 5P5 5.76923
164 1LES GLC FRU 5.76923
165 2JBH 5GP 5.77778
166 5DNC ASN 5.80808
167 3HQP FDP 5.80808
168 5NTD BES 5.80808
169 3OID TCL 5.81395
170 2UVO NAG 5.84795
171 4K7O EKZ 5.95238
172 4R8L ASP 5.97403
173 1T36 ORN 6.06061
174 3UYW TAU 6.07477
175 3K7S R52 6.14525
176 5ZI9 FLC 6.15385
177 2IBN I1N 6.4
178 4D9C PMP 6.43275
179 4BG4 ARG 6.46067
180 4Q3R XA2 6.49351
181 5YRV 5AD 6.5
182 1YBU APC 6.52174
183 4HSE ADP 6.56566
184 4EVQ PHB 6.56566
185 2HJ4 PNZ 6.66667
186 2XKO AKG 6.74157
187 2PEL LBT 6.77966
188 2YFO GLA 6.81818
189 2YFO GAL 6.81818
190 4HEQ FMN 6.84932
191 5CGE 51F 6.85921
192 1GXS BEZ 6.96203
193 4LFL TG6 6.97674
194 2F9W PAU 7.01107
195 4BHL ARG 7.02247
196 4YDU ADP 7.28863
197 3HUN ZZ7 7.32323
198 4CCW VKC 7.35786
199 3AB4 THR 7.36342
200 5HC0 NPO 7.39726
201 5IFK HPA 7.69231
202 2EG7 OTD 7.78098
203 4UP4 GAL NAG 7.82828
204 5I0U DCY 8
205 3PPQ CHT 8.03859
206 1OHE ACE ALA SEP PRO 8.04598
207 1PMO PLR 8.08081
208 4FBL SPD 8.18505
209 2VAR AMP 8.30671
210 5GZK BGC 8.33333
211 4B2D FBP 8.33333
212 1JI0 ATP 8.33333
213 2I6U NVA 8.46906
214 5GVR LMR 8.54701
215 5TG5 JW8 8.57143
216 1II5 GLU 8.58369
217 2A9G ARG 8.58586
218 2OHH FMN 8.58586
219 3QH2 3NM 8.59729
220 5NUL FMN 8.69565
221 4P86 5GP 8.74317
222 4P83 U5P 8.79121
223 3GXA MET 8.83838
224 4FHT DHB 8.9172
225 1V7Z CRN 9.23077
226 3A4M ADP 9.23077
227 1WAP TRP 9.33333
228 5TQZ GLC 9.33333
229 4UIN QI9 9.33333
230 1QAW TRP 9.45946
231 5VEG FMN 9.55056
232 4D9M 0JO 9.59596
233 1UJ5 5RP 9.69163
234 3KB6 LAC 9.88024
235 1V7C HEY 9.97151
236 3A6T 8OG 10.0775
237 2J5V RGP 10.0817
238 1IR3 ANP 10.1307
239 1XXA ARG 10.2564
240 5IWQ PLP 10.3535
241 6HKE LMR 10.3774
242 6HKE MLT 10.3774
243 3N9R TD3 10.4235
244 2VHL GLP 10.6061
245 4CQM NAP 10.6557
246 3O5N BR0 10.7143
247 3ZZQ TRP 10.7692
248 3ZZS TRP 10.7692
249 2X61 CH 10.8527
250 2HU5 GLY PHE 10.8586
251 3HP8 SUC 10.9091
252 3I9U DTU 11.0266
253 6GAQ FMN 11.039
254 5D85 P1T 11.0429
255 4U00 ADP 11.0656
256 4YMZ 13P 11.1554
257 5M45 AMP 11.3095
258 1VB3 KPA 11.3636
259 4RHE FMN 11.9617
260 3PC3 P1T 12.1212
261 1RLJ FMN 12.2302
262 1MFA GLA MMA ABE 12.5
263 3WLV AZA 12.5
264 3X44 PUS 12.6506
265 5YJS SAL 12.8205
266 5X2N ALA 13.6364
267 2D0V PQQ 13.8889
268 5XL4 SIA 14.2045
269 6EBQ FMN 14.375
270 1U6R ADP 14.4737
271 4F8L AES 14.4828
272 4H2D FMN 14.5455
273 6C2Z P1T 14.6667
274 2FCR FMN 15.0289
275 2AJH MET 15.3061
276 3IR1 MET 15.5102
277 3LN9 FLC 15.8273
278 4EKQ NPO 16.0428
279 2ZHZ ATP 16.3934
280 5B3A 0JO 16.4524
281 5O2J 2PO 16.8498
282 4USI AKG 16.8831
283 5I7A 68Q 18.0982
284 6BYF CIT 18.2353
285 3F6R FMN 22.2973
286 2JGV ADP 23.0303
287 3L6R MLI 23.1214
288 1J0D 5PA 23.1672
289 3MN5 LAB 23.6842
290 2PS1 ORO 23.8938
291 3L6C MLI 24.4838
292 2FWP CIT 25.1366
293 4JBL MET 35.1032
294 1D6S MET PLP 38.8199
295 1D6S PLP MET 38.8199
296 3VC3 C6P 39.5349
297 3ZEI AWH 45.1613
Pocket No.: 2; Query (leader) PDB : 6AMI; Ligand: TRP; Similar sites found with APoc: 69
This union binding pocket(no: 2) in the query (biounit: 6ami.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 2NLQ GLY None
2 4OKD GLC GLC GLC 1.26263
3 2Q8E OGA 1.42045
4 4JE5 PMP 1.76768
5 4Z0G 5GP 1.76768
6 2EXK XYS XYS 2.0202
7 4ZO3 C6L 2.04082
8 5H9I XAN 2.08333
9 4TVD BGC 2.77778
10 1LAN LEU 3.0303
11 2IMP LAC 3.0303
12 1GPM CIT 3.0303
13 3B1Q NOS 3.06748
14 1BW9 PPY 3.08989
15 4A8H PUW 3.09859
16 5JVB 2PO 3.21429
17 1V6A TRE 3.31325
18 4PVR ASP 3.54839
19 5LU5 M7P 3.5533
20 2XZ9 PYR 3.7037
21 6GSZ BGC 3.78788
22 2VVT DGL 3.7931
23 1L5Y BEF 3.87097
24 5OFW 9TW 4.03587
25 5NN0 92H 4.0404
26 3N8K D1X 4.06977
27 5FUS DAO 4.18118
28 4P5Y NGA 4.19162
29 2X8S AHR AHR AHR 4.29293
30 3DFR MTX 4.32099
31 5X80 SAL 4.375
32 2DTJ THR 4.49438
33 3N75 G4P 4.54545
34 5N53 8NB 4.61538
35 4NTX AMR 5
36 2PHU MAN MAN 5.30303
37 2GND MAN 5.30303
38 1UKG MMA 5.30303
39 5AHO TLA 5.35714
40 5CC2 CKA 6.03774
41 1BGV GLU 6.06061
42 5CWA 0GA 6.31313
43 3BF1 PAU 6.4257
44 4ZCW 4NG 6.81818
45 4YC9 4C1 7.06522
46 3U7Q HCA 7.07071
47 1P4V GLY 7.11864
48 2HFN FMN 7.18954
49 2GMV PEP 7.32323
50 1OS7 TAU 7.77385
51 3F81 STT 8.19672
52 3BQF SSM 8.24742
53 2I6U CP 8.46906
54 4OUE IPT 8.58586
55 2QRD ATP 8.68263
56 3B8I OXL 8.83838
57 3NJ4 AFX 8.83838
58 5ZI7 GLU 9.59596
59 1Z17 ILE 9.88372
60 1APZ ASP 9.92908
61 3D1R FBP 10.9792
62 1X0P FAD 11.1888
63 2ZQO NGA 12.3077
64 3GNE FLC 15.0794
65 4C2W ANP 15.3846
66 4OWK NGA 15.942
67 5KWY C3S 18.0451
68 5D6J ATP 21.6216
69 4HBM 0Y7 25.8333
Pocket No.: 3; Query (leader) PDB : 6AMI; Ligand: TRP; Similar sites found with APoc: 52
This union binding pocket(no: 3) in the query (biounit: 6ami.bio3) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 1V08 NTZ 1.26263
2 2YFT DQR 1.26263
3 4AQ4 G3P 1.26263
4 5A1S FLC 1.76768
5 2WR1 SIA GAL NAG 1.76768
6 1ZGS XMM 1.76768
7 2PCU ASP 1.96721
8 2YGM GLA NAG GAL FUC 1.9774
9 5E58 CPZ 2.0202
10 2Z49 AMG 2.0202
11 3CZG GLC 2.0202
12 1GJW GLC 2.0202
13 6B2W AG2 2.1021
14 1J2Z SOG 2.59259
15 2NZ2 ASP 2.77778
16 5AHM IMP 3.0303
17 3AJ6 NGA 3.0303
18 5AHN IMP 3.0303
19 4WBD CIT 3.0303
20 4FE3 U5P 3.0303
21 2OI2 DP6 3.08219
22 3DGB MUC 3.14136
23 1SW0 PGA 3.22581
24 1EQ2 ADQ 3.22581
25 5OES ADP 3.28283
26 2ZUX RAM 3.53535
27 3G6N MET ALA SER 3.66492
28 1TE2 PGA 3.9823
29 3K8D KDO 4.16667
30 4A59 AMP 4.54545
31 6CI9 F3V 4.6332
32 2EFX NFA 4.6832
33 2HIM ASP 4.7486
34 5TSH ADP 4.79798
35 3QPB URA 4.96454
36 2WG9 OCA 5.38462
37 4Z7X 3CX 5.46218
38 1M7G AV2 5.6872
39 2QHV OC9 5.71429
40 1M0S CIT 5.93607
41 3MMH SME 5.98802
42 4C6H HE2 6.87285
43 1XG4 ICT 7.45763
44 2IW3 ADP 7.57576
45 1B4U DHB 7.91367
46 4UHL VFV 8.08081
47 5AHW CMP 8.16327
48 1Y7P RIP 8.52018
49 3WCS MAN NAG GAL 8.66142
50 3JQM GTP 8.9172
51 3ZJX BOG 11.4187
52 1Y4Z PCI 20
Pocket No.: 4; Query (leader) PDB : 6AMI; Ligand: TRP; Similar sites found with APoc: 98
This union binding pocket(no: 4) in the query (biounit: 6ami.bio3) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 4I53 1C1 1.39665
2 5IKI A9H 1.51515
3 3R75 PYR 1.51515
4 1O5Q PYR 1.63934
5 3CL7 HYN 1.94805
6 4XBA 5GP 2
7 2X1L ADN 2.0202
8 2WKW W22 2.13415
9 1G8S MET 2.17391
10 4QCK ASD 2.33161
11 5XQL C2E 2.4055
12 5A96 GTP 2.40964
13 1L5J TRA 2.52525
14 4XWT U5P 2.52525
15 4MNP SLB 2.5641
16 1IK4 PGH 2.63158
17 2XCU C5P 2.6738
18 3EXS 5RP 2.71493
19 1WD4 AHR 2.77778
20 2NNJ 225 2.77778
21 2F2H XTG 2.77778
22 1Q6O LG6 2.77778
23 1KPG SAH 2.78746
24 1QDS PGA 2.78884
25 3VGL BGC 2.80374
26 2VVG ADP 2.85714
27 4HE2 AMP 2.95858
28 4L77 CNL 3.0303
29 3DRW AMP 3.0303
30 1C1X HFA 3.09859
31 3K5I AIR 3.28283
32 1T9D 1MM 3.28283
33 5WS9 OXL 3.28283
34 4NST ADP 3.4188
35 4AG5 ADP 3.53535
36 1OBV FMN 3.5503
37 4GGL CJC 3.72093
38 1M26 GAL A2G 3.7594
39 4O1Z MXM 3.78788
40 5I34 IMP 3.78788
41 1C7R PA5 4.0404
42 3F4F UMP 4.19162
43 2GQS C2R 4.21941
44 1U5R ATP 4.31034
45 3WUC GLC GAL 4.37956
46 6C0B MLI 4.48718
47 1WOQ BGC 4.49438
48 3ZFD ANP 4.5584
49 2YVJ NAI 4.58716
50 3KAP FMN 4.7619
51 5KZD RCJ 4.77816
52 3CF6 SP1 4.79042
53 1WM1 PTB 4.79798
54 1OYF MHN 4.95868
55 3OCP CMP 5.03597
56 4BI7 PGA 5.05837
57 1NYT NAP 5.53506
58 3FJO FMN 5.55556
59 1BTN I3P 5.66038
60 2RIF AMP 5.67376
61 2PZE ATP 5.67686
62 4YMU ATP 5.90909
63 3ZKN WZV 5.9633
64 4PPF FLC 6
65 2Q8M AMP 6.0241
66 5YSN 5AD 6.1017
67 1NW4 IMH 6.15942
68 4INB 1F6 6.16438
69 1GVF PGH 6.29371
70 5IDB BMA 6.33803
71 6HT0 GQ8 6.45161
72 3NHB ADP 6.53595
73 5LJI FMN 6.75676
74 2OEM 1AE 6.81818
75 5EPO NAP 6.87023
76 1JJ7 ADP 6.92308
77 3E70 GDP 7.0122
78 4XFR CIT 7.02576
79 5UXH GFB 7.35695
80 2DUA OXL 7.58621
81 1VHT BA3 8.25688
82 4QM7 GTP 8.77193
83 6FSG FMN 8.84354
84 5C9J DAO 9.09091
85 1T57 FMN 9.70874
86 3AIA SAM 9.95261
87 5UMY TNN 10
88 3PH4 AOS 10.0592
89 1WBI BTN 10.0775
90 1SGJ OAA 10.5634
91 4FMS BDP 11.6162
92 3PQC GDP 12.3077
93 1TH8 ADP 12.931
94 1I58 ADP 13.2275
95 4R5E AO3 14.6552
96 4JLS 3ZE 15.7895
97 2IMG MLT 19.8675
98 1GT4 UNA 30.8176
Pocket No.: 5; Query (leader) PDB : 6AMI; Ligand: TRP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 6ami.bio4) has 32 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 6AMI; Ligand: TRP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 6ami.bio4) has 42 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 6AMI; Ligand: TRP; Similar sites found with APoc: 9
This union binding pocket(no: 7) in the query (biounit: 6ami.bio4) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 1Q8A HCS 2.77778
2 2D24 XYS XYS 3.53535
3 1QMG DMV 4.54545
4 1W62 PYC 5.55556
5 6APF CIT 6.04982
6 2BTM PGA 8.33333
7 1WHT BZS 9.15033
8 3H8G BES 9.84848
9 6D50 GCB 10.3535
Pocket No.: 8; Query (leader) PDB : 6AMI; Ligand: TRP; Similar sites found with APoc: 7
This union binding pocket(no: 8) in the query (biounit: 6ami.bio4) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 3QSB 743 2.73224
2 1OFU GDP 3.125
3 5XGX DAS DLY 4.05063
4 5HWV MBN 5.38462
5 1N4K I3P 11.0236
6 2W5P CL8 11.4094
7 3SAO NKN 13.125
Pocket No.: 9; Query (leader) PDB : 6AMI; Ligand: TRP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 9) in the query (biounit: 6ami.bio2) has 32 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 10; Query (leader) PDB : 6AMI; Ligand: TRP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 6ami.bio2) has 33 residues
No: Leader PDB Ligand Sequence Similarity
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