Receptor
PDB id Resolution Class Description Source Keywords
5J1J 1.55 Å NON-ENZYME: OTHER STRUCTURE OF FLEN-AMPPNP COMPLEX PSEUDOMONAS AERUGINOSA PAO1 FLEN TRANSCRIPTION ANTIACTIVATOR AMPPNP
Ref.: ATP-INDUCED STRUCTURAL REMODELING IN THE ANTIACTIVA ENABLES FORMATION OF THE FUNCTIONAL DIMERIC FORM STRUCTURE V. 25 243 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 A:303;
A:302;
B:503;
B:502;
A:304;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
MG B:504;
A:305;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ANP A:301;
B:501;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5J1J 1.55 Å NON-ENZYME: OTHER STRUCTURE OF FLEN-AMPPNP COMPLEX PSEUDOMONAS AERUGINOSA PAO1 FLEN TRANSCRIPTION ANTIACTIVATOR AMPPNP
Ref.: ATP-INDUCED STRUCTURAL REMODELING IN THE ANTIACTIVA ENABLES FORMATION OF THE FUNCTIONAL DIMERIC FORM STRUCTURE V. 25 243 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 5J1J - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 5J1J - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 5J1J - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5J1J; Ligand: ANP; Similar sites found: 412
This union binding pocket(no: 1) in the query (biounit: 5j1j.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3COB ADP 0.00001456 0.40837 1.40351
2 3H4S ADP 0.0000159 0.40608 1.40351
3 4FRZ ADP 0.00005082 0.40302 1.40351
4 2W58 ADP 0.000001723 0.41227 1.48515
5 5KSP GDP 0.0002199 0.4923 1.57895
6 4IDN GNP 0.0005487 0.4455 1.75439
7 3P7G MAN 0.03109 0.40022 2.05479
8 5HCN GCP 0.000006991 0.56384 2.10526
9 1G7S GDP 0.000025 0.53741 2.10526
10 4IEE AGS 0.001366 0.46495 2.10526
11 1TAD GDP 0.0000507 0.44689 2.10526
12 1TAD ALF 0.0000507 0.44689 2.10526
13 2F5X ASP 0.01908 0.41157 2.10526
14 2AWN ADP 0.0000004606 0.41103 2.10526
15 2GWH A3P 0.01014 0.40174 2.10526
16 2XTN GTP 0.0001184 0.46895 2.13675
17 2CHG ANP 0.0004558 0.42143 2.21239
18 4HSE ADP 0.0001158 0.42008 2.267
19 3QBT GNP 0.00005196 0.46747 2.29885
20 1EK0 GNP 0.00004294 0.47035 2.35294
21 2PHN GDP 0.005446 0.40223 2.3622
22 1DAR GDP 0.000012 0.56017 2.45614
23 2ODE ALF GDP 0.00005061 0.49405 2.45614
24 1YTM ATP 0.0004144 0.4548 2.45614
25 1SKQ GDP 0.000006155 0.44591 2.45614
26 3ZFD ANP 0.0001623 0.42647 2.45614
27 1P72 ADP 0.003377 0.42117 2.45614
28 4D81 ADP 0.0002913 0.42181 2.4735
29 1D2N ANP 0.001366 0.43263 2.57353
30 3REF GDP 0.0002933 0.4569 2.57732
31 1A4R GNH 0.0002805 0.47137 2.6178
32 1A4R GDP 0.0003506 0.46237 2.6178
33 1KSH GDP 0.00005888 0.46901 2.63158
34 2ZEJ GDP 0.0001387 0.44437 2.71739
35 1YZG GDP 0.000002596 0.58439 2.7933
36 1SQ5 ADP 0.00008301 0.51251 2.80702
37 2JLR ANP 0.0001877 0.48434 2.80702
38 2BVN GNP 0.000008507 0.47713 2.80702
39 2XTZ GSP 0.00005828 0.46545 2.80702
40 5CK5 GDP 0.000005837 0.45143 2.80702
41 1D8T GDP 0.00001115 0.44834 2.80702
42 1FNN ADP 0.0001562 0.44758 2.80702
43 2HCJ GDP 0.000006412 0.44712 2.80702
44 3SBD GNP 0.0001754 0.44707 2.80702
45 5FG3 GDP 0.000009944 0.44219 2.80702
46 3A1S GDP 0.00005171 0.43877 2.80702
47 4YS0 ADP 0.001661 0.43689 2.80702
48 2B8W ALF 5GP 0.001102 0.43095 2.80702
49 2J5V PCA 0.01546 0.4234 2.80702
50 2WHX ADP 0.00003977 0.40803 2.80702
51 4Q1A UDP 0.00788 0.45994 2.85714
52 4Q1A 2XZ 0.00788 0.45994 2.85714
53 4R2I ANP 0.01218 0.42171 2.85714
54 3B5J 12D 0.00005688 0.54192 2.88066
55 3BOS CDP 0.0002156 0.49877 2.89256
56 4V0K GDP 0.0001602 0.45603 2.95858
57 3Q72 GNP 0.000001128 0.46984 3.01205
58 4AG5 ADP 0.000008526 0.58895 3.15789
59 1Z08 GNP 0.00004723 0.48536 3.15789
60 4RD0 GDP 0.00003593 0.48356 3.15789
61 1NY5 ADP 0.0003073 0.4696 3.15789
62 4A4Z ANP 0.000925 0.4678 3.15789
63 4KBF AMP 0.001769 0.45932 3.15789
64 2VVG ADP 0.00000707 0.40444 3.15789
65 1WRA PC 0.02204 0.40441 3.15789
66 3GJ0 GDP 0.000004742 0.5799 3.16742
67 3GJ7 GDP 0.000004783 0.57971 3.16742
68 3GJ3 GDP 0.000006535 0.57308 3.16742
69 3GJ5 GDP 0.000007848 0.56144 3.16742
70 1MH1 GNP 0.0002446 0.46172 3.22581
71 3DKP ADP 0.0001385 0.41507 3.26531
72 1KY3 GDP 0.00001884 0.46705 3.2967
73 4G6I RS3 0.007369 0.40788 3.33333
74 1HE1 GDP 0.0003412 0.45841 3.40909
75 3CX8 GSP 0.00006633 0.48909 3.44828
76 4WZ6 ATP 0.00003179 0.56085 3.50877
77 2FFQ GSP 0.00006513 0.48572 3.50877
78 1IBR GNP 0.00006564 0.48558 3.50877
79 2A5F GTP 0.0000698 0.47026 3.50877
80 1OYY AGS 0.0009078 0.4682 3.50877
81 4NU0 AP5 0.0004711 0.46458 3.50877
82 2VF7 ADP 0.0009414 0.46212 3.50877
83 1W5T ANP 0.0001978 0.44845 3.50877
84 4PJ3 ANP 0.001271 0.44643 3.50877
85 5GJC ATP 0.00002118 0.44188 3.50877
86 1Z6T ADP 0.0001428 0.44094 3.50877
87 2Q2Y MKR 0.004287 0.42384 3.50877
88 2Q2Y ADP 0.004535 0.42384 3.50877
89 1W5T ADP 0.0008048 0.41338 3.50877
90 4BAS GNP 0.00004742 0.47894 3.51759
91 1YZQ GNP 0.0000712 0.45537 3.52941
92 1LVG ADP 0.00000131 0.6263 3.53535
93 4MKF AP5 0.000491 0.46744 3.68664
94 2WJG GDP 0.000003221 0.46829 3.7234
95 1ZJ6 G3D 0.000003367 0.579 3.74332
96 2RCN GDP 0.000003372 0.58715 3.85965
97 2XT3 ADP 0.0000288 0.56614 3.85965
98 2NGR GDP 0.00004144 0.52692 3.85965
99 1V8K ANP 0.000061 0.5256 3.85965
100 2FJU GSP 0.0001683 0.47155 3.85965
101 3AB3 GDP 0.00006431 0.46681 3.85965
102 4LC1 GDP 0.000004443 0.46361 3.85965
103 5L3W GDP 0.00002476 0.45667 3.85965
104 1KK1 GNP 0.000003787 0.45206 3.85965
105 5TSH ANP 0.00005976 0.42845 3.85965
106 2ZFI ADP 0.00006509 0.42819 3.85965
107 2QEN ADP 0.0004333 0.4227 3.85965
108 2ZR9 DTP 0.0002126 0.41446 3.85965
109 2NGR AF3 0.01854 0.41223 3.85965
110 4DID GDP 0.0001315 0.4232 3.94737
111 4M9Q GNP 0.0001004 0.47642 3.96476
112 1XKV ATP 0.0003938 0.47478 3.96975
113 2HT6 GDP 0.000001201 0.61836 4.02299
114 2G77 GDP 0.00003997 0.46098 4.0404
115 5H56 ADP 0.001409 0.43457 4.10256
116 5H56 TYD 0.001409 0.43457 4.10256
117 1NRJ GTP 0.00005431 0.49257 4.12844
118 3Q85 GNP 0.000003443 0.46575 4.14201
119 1ZIN AP5 0.0009684 0.4533 4.14747
120 4QOS ADP 0.0001715 0.49164 4.15094
121 2CJW GDP 0.000002046 0.59776 4.16667
122 3W5J GDP 0.0000002794 0.67388 4.21053
123 1G4U GDP 0.0001535 0.47804 4.21053
124 3TBK ANP 0.001024 0.47724 4.21053
125 1TQ4 GDP 0.00004895 0.47257 4.21053
126 1O3Y GTP 0.0001221 0.4684 4.21053
127 1E96 GTP 0.0002872 0.45699 4.21053
128 1AZT GSP 0.00005619 0.44593 4.21053
129 5I0H ADP BEF 0.0003667 0.43774 4.21053
130 4H1V GNP 0.0002606 0.43559 4.21053
131 1SVM ATP 0.00459 0.4304 4.21053
132 3BFX A3P 0.005872 0.40885 4.21053
133 5HR5 ADP 0.001276 0.40506 4.21053
134 5I34 GDP 0.0005799 0.40276 4.21053
135 2WJH GDP 0.000008186 0.46443 4.21687
136 2WJH FLC 0.000017 0.46314 4.21687
137 4NON GDP 0.0003262 0.45823 4.23077
138 1Z06 GNP 0.0001031 0.47349 4.2328
139 2IXE ATP 0.0009185 0.42777 4.42804
140 1GRN GDP 0.0001688 0.43767 4.4335
141 3FVQ ATP 0.0004557 0.43386 4.45682
142 4R43 GDP 0.000389 0.48622 4.47284
143 4OI4 ATP 0.0001346 0.46666 4.5614
144 1GOT GDP 0.0001173 0.46357 4.5614
145 5BXQ GDP 0.00001038 0.46163 4.5614
146 1YZN GNP 0.00006181 0.45796 4.5614
147 1RYH GNP 0.00004368 0.44516 4.5614
148 1L2T ATP 0.002358 0.41729 4.5614
149 1KO8 6PG 0.0002427 0.44004 4.57143
150 1PUJ GNP 0.000004997 0.55618 4.60993
151 1SVI GDP 0.00003086 0.54759 4.61538
152 4QM7 GTP 0.0003553 0.48815 4.67836
153 2A5J GDP 0.00001047 0.54831 4.71204
154 1YVD GNP 0.00006057 0.48508 4.73373
155 1VG8 GNP 0.00003979 0.49466 4.83092
156 1VG0 GDP 0.00002366 0.46364 4.83092
157 2BME GNP 0.00006497 0.48381 4.83871
158 4WOP CTP 0.0000852 0.46404 4.88889
159 1M2O GNP 0.00002263 0.50285 4.91228
160 2QTV GNP 0.00007325 0.46977 4.91228
161 3RLF ANP 0.0005065 0.44301 4.91228
162 3RC3 ANP 0.0132 0.41539 4.91228
163 2I4I AMP 0.00731 0.40811 4.91228
164 3QKT ANP 0.003886 0.4012 4.91228
165 2GDJ ANP 0.0001065 0.42039 4.92424
166 2F9L GDP 0.00006897 0.4786 5.02513
167 1Z83 AP5 0.006793 0.4094 5.10204
168 4R98 GNH 0.00002379 0.44588 5.16605
169 2GJ8 ALF GDP 0.00004749 0.46147 5.23256
170 1OIX GDP 0.0000362 0.49437 5.2356
171 1OIV GDP 0.00006896 0.48274 5.2356
172 1Z0A GDP 0.000007289 0.55564 5.26316
173 1R2Q GNP 0.000078 0.49429 5.26316
174 1TU3 GNP 0.00004881 0.48897 5.26316
175 1Z2A GDP 0.00004326 0.48693 5.26316
176 1F5N GNP 0.0001764 0.46764 5.26316
177 4LJ9 ACP 0.001017 0.46579 5.26316
178 3TK1 GDP 0.000004818 0.44313 5.26316
179 1M7G ADX 0.002295 0.427 5.26316
180 1M7G AV2 0.00004579 0.4208 5.26316
181 2BIF ANP 0.003792 0.4203 5.26316
182 2BIF SIN 0.006381 0.4203 5.26316
183 1M7G ADP 0.00367 0.41552 5.26316
184 4FCW ADP 0.0002859 0.41416 5.26316
185 5UQW GDP 0.0001096 0.47239 5.29101
186 4DSU GDP 0.0001231 0.44637 5.29101
187 1QHH ATP 0.009316 0.41448 5.32544
188 5TAR GDP 0.00000519 0.55543 5.40541
189 5TB5 GDP 0.000003391 0.48391 5.40541
190 1VG1 GDP 0.000006044 0.46646 5.40541
191 2W2X GSP 0.0002703 0.46275 5.40541
192 1VG9 GDP 0.00001563 0.45566 5.40541
193 1MKY GDP 0.000002365 0.59469 5.61404
194 5L3S GNP 0.000002419 0.54085 5.61404
195 5L3V GDP 0.00001919 0.53602 5.61404
196 1ZC3 GNP 0.00001296 0.51501 5.61404
197 1U8Z GDP 0.00002185 0.49912 5.61404
198 2OM2 GDP 0.00004935 0.49434 5.61404
199 5BQ5 ADP BEF 0.00016 0.49304 5.61404
200 5KSZ GCP 0.000223 0.48631 5.61404
201 1Y3A GDP 0.0001238 0.46816 5.61404
202 1WA5 GTP 0.00006186 0.43244 5.61404
203 1OS1 PYR 0.002183 0.42651 5.61404
204 1OS1 ATP 0.002225 0.42471 5.61404
205 3ZS9 ADP ALF 0.000000001363 0.68121 5.64972
206 4XTR ATP 0.000000003724 0.654 5.64972
207 4XVU ATP 0.000000004506 0.6506 5.64972
208 2WOJ ADP ALF 0.000000001392 0.63188 5.64972
209 4XTR ADP 0.00000003689 0.58382 5.64972
210 4C4P GNP 0.00003439 0.49731 5.78035
211 4LPS GDP 0.00003353 0.44092 5.78512
212 1I4D GDP 0.0001031 0.52129 5.80357
213 2HV8 GTP 0.00003265 0.49623 5.81395
214 4PX9 ADP 0.0001241 0.41037 5.82192
215 5XCO GDP 0.00001802 0.46704 5.84795
216 5O2T GSP 0.00006373 0.4573 5.91716
217 2BCG GDP 0.00004492 0.50135 5.96491
218 5LB3 ADP 0.0003547 0.49436 5.96491
219 3BC1 GNP 0.00005127 0.48809 5.96491
220 4ITR GDP 0.000571 0.45311 5.96491
221 2D7C GTP 0.00002778 0.49915 5.98802
222 1LFD GNP 0.00002749 0.47821 5.98802
223 1CLU DBG 0.00006813 0.5065 6.0241
224 5UFQ GNP 0.00002656 0.49996 6.0241
225 3DDC GNP 0.00003127 0.49903 6.0241
226 1NVU GTP 0.00003297 0.49807 6.0241
227 2UZI GTP 0.00005587 0.48654 6.0241
228 3KUD GDP 0.00002407 0.48393 6.0241
229 1NVV GNP 0.0000293 0.46967 6.0241
230 3T5G GDP 0.00002909 0.4516 6.07735
231 1XTQ GDP 0.00009184 0.47349 6.21469
232 1S8F GDP 0.00004369 0.45646 6.21469
233 3WXM GTP 0.00006267 0.48446 6.31579
234 1NJF AGS 0.00007545 0.47109 6.31579
235 1NJF ADP 0.000127 0.44981 6.31579
236 5X40 ACP 0.001941 0.41901 6.31579
237 3CV2 OXL 0.029 0.40597 6.31579
238 1ZD9 GDP 0.00007815 0.45717 6.38298
239 1S9D GDP 0.000009484 0.55752 6.40394
240 3GJ8 GDP 0.00000734 0.46545 6.52174
241 1M7B GTP 0.0005785 0.42997 6.52174
242 4K81 GTP 0.00003806 0.45931 6.58915
243 3UIE ANP 0.00009803 0.43482 6.66667
244 4ZG4 VO4 ADP 0.0009048 0.43265 6.66667
245 1DS6 GDP 0.0000693 0.42535 6.66667
246 3DC4 ADP 0.00004127 0.41399 6.66667
247 1U25 IHS 0.01552 0.40461 6.66667
248 1Z0F GDP 0.000003299 0.57942 6.70391
249 2WIC GNP 0.0000009969 0.49204 6.74157
250 2PL3 ADP 0.0001662 0.51088 6.77966
251 2QZ4 ADP 0.0001631 0.49265 6.87023
252 1UKZ ADP 0.003213 0.4234 6.89655
253 1JJ7 ADP 0.00001057 0.59277 6.92308
254 1H65 GDP 0.00004718 0.49017 7.01754
255 1GOJ ADP 0.000004727 0.40764 7.01754
256 43CA NPO 0.02105 0.41162 7.07965
257 4CVN ADP 0.00004984 0.54488 7.29927
258 1R6B ADP 0.0001983 0.49445 7.36842
259 1X6V ADP 0.002841 0.42022 7.36842
260 1VHT BA3 0.0005361 0.41096 7.36842
261 5KUT GDP 0.00004522 0.44151 7.40741
262 1G7C 5GP 0.0009977 0.46619 7.44681
263 2FH5 GTP 0.00004878 0.49456 7.47664
264 5N69 ADP 0.0003056 0.47468 7.53769
265 1CS4 GSP 0.00007523 0.44696 7.54717
266 1BH2 GSP 0.00008089 0.44101 7.61905
267 1B7T ADP 0.0004007 0.47444 7.69231
268 3RAB GNP 0.0001496 0.46876 7.69231
269 4NCN GTP 0.0001123 0.46989 7.7193
270 2FAH GDP 0.000593 0.46155 7.7193
271 2IYL GDP 0.000005032 0.46071 7.7193
272 2WKQ GTP 0.0001903 0.46048 7.7193
273 1IWE IMP 0.008247 0.44514 7.7193
274 4IOK ADP 0.02392 0.40533 7.7193
275 1KK8 BEF ADP 0.0005999 0.45663 7.79221
276 4MKG AP5 0.0003848 0.47091 7.8341
277 4P32 ADP 0.004834 0.40584 8.03213
278 3E70 GDP 0.00002266 0.53945 8.07018
279 1YRB GDP 0.000002763 0.49645 8.07018
280 3FYH ADP 0.001651 0.42369 8.07018
281 1OXV ANP 0.00009835 0.41031 8.07018
282 1RE0 GDP 0.000003672 0.45413 8.1448
283 1FQJ GDP 0.00007877 0.47623 8.16327
284 1FQK GDP 0.0001128 0.46982 8.16327
285 1FQK ALF 0.0174 0.41666 8.16327
286 1FZQ GDP 0.00000665 0.57271 8.28729
287 1IHU ADP 0.00000004401 0.60992 8.42105
288 1IHU AF3 0.00000006634 0.60974 8.42105
289 1SVK ALF GDP 0.00005674 0.49372 8.42105
290 1WQ1 GDP 0.00004429 0.48651 8.42105
291 3B7G ANP 0.0001841 0.42131 8.42105
292 1JJV ATP 0.000007262 0.59324 8.73786
293 1GWN GTP 0.0008081 0.42435 8.78049
294 2VQD AP2 0.001802 0.42748 9.12281
295 3RWO GDP 0.00007887 0.48031 9.18919
296 3H86 AP5 0.002097 0.43265 9.375
297 3IIJ ADP 0.00001997 0.54934 9.47368
298 2XAU ADP 0.002312 0.43889 9.47368
299 2ZPA ADP 0.0008409 0.41771 9.47368
300 2IS6 ADP 0.0001026 0.41479 9.47368
301 3T12 GDP ALF 0.00001918 0.49476 9.59596
302 3T1O GDP 0.000003062 0.4847 9.59596
303 1F6B GDP 0.000008202 0.46576 9.59596
304 4HI0 GDP 0.00002809 0.48131 9.81132
305 2C78 GNP 0.0000155 0.49844 9.82456
306 3M1I GTP 0.00004094 0.49415 9.82456
307 4HAT GNP 0.000051 0.49207 9.82456
308 5UWP GNP 0.00005568 0.49047 9.82456
309 5DI9 GNP 0.00005629 0.49027 9.82456
310 5UWR GNP 0.0000509 0.4902 9.82456
311 5UWT GNP 0.00005101 0.49016 9.82456
312 5UWI GNP 0.00005236 0.48968 9.82456
313 5UWU GNP 0.00005605 0.48845 9.82456
314 1WF3 GNP 0.00005804 0.48781 9.82456
315 2C77 GNP 0.00003493 0.47703 9.82456
316 5UWH GNP 0.00004593 0.46281 9.82456
317 5UWQ GNP 0.00004924 0.4617 9.82456
318 5DIF GNP 0.00005044 0.46137 9.82456
319 5UWJ GNP 0.00005196 0.46081 9.82456
320 5UWO GNP 0.00005366 0.46041 9.82456
321 5DHF GNP 0.00005411 0.46018 9.82456
322 5UWW GNP 0.00005901 0.45893 9.82456
323 5UWS GNP 0.00006279 0.45112 9.82456
324 4PFO ADP 0.000592 0.44392 9.82456
325 2VB6 ADP BEF 0.001139 0.42854 9.82456
326 1OW3 GDP 0.0001193 0.44245 9.84456
327 1W0J ADP BEF 0.0001428 0.44913 9.92647
328 1W0J ADP 0.0004603 0.41492 9.92647
329 1MR3 G3D 0.000004662 0.47429 9.94475
330 4YMU ATP 0.0001116 0.51957 10
331 3QF7 ANP 0.001948 0.40498 10
332 1Z0J GTP 0.0000553 0.48869 10.1695
333 4B47 GDP 0.000007392 0.57874 10.1754
334 5IRC GDP 0.0004555 0.40864 10.2151
335 4BQS K2Q 0.001166 0.44493 10.2273
336 4BQS ADP 0.001166 0.44493 10.2273
337 4D0N GDP 0.00002375 0.43865 10.2703
338 5HPY GDP 0.0001742 0.43705 10.2703
339 1KMQ GNP 0.0003059 0.45201 10.3261
340 4GOX A3P 0.003699 0.40749 10.5431
341 1A8S PPI 0.01757 0.41822 10.6227
342 1TX4 ALF GDP 0.0002867 0.45317 10.7345
343 5KDO GDP 0.00006884 0.48816 10.8108
344 2J0V GDP 0.00007691 0.43076 10.8491
345 1JWY GDP 0.00001328 0.4744 10.8772
346 1JWY ADP 0.000126 0.42164 10.8772
347 2XG5 EC2 0.01233 0.42906 10.9827
348 2XG5 EC5 0.01233 0.42906 10.9827
349 2HF9 GSP 0.00006102 0.48494 11.0619
350 1KAO GDP 0.00001224 0.53208 11.2281
351 5MZN ADP 0.0009756 0.47832 11.2281
352 3DEF GDP 0.00001052 0.47637 11.4504
353 3P4X ADP 0.00005074 0.42349 11.5789
354 4TTQ ATP 0.0002094 0.41355 11.5789
355 1CXZ GSP 0.0005415 0.43651 11.6279
356 3MJH GTP 0.00005268 0.46736 11.7647
357 1G16 GDP 0.0001088 0.46477 11.7647
358 3DZD ADP 0.0006171 0.46076 11.9298
359 3EC1 GDP 0.00009401 0.43005 11.9298
360 3ZIA ADP 0.0005939 0.41073 12.2807
361 3ZIA ATP 0.0002889 0.40868 12.2807
362 4U5X GNP 0.00009503 0.45426 12.3596
363 1GUA GNP 0.00003188 0.46835 12.5749
364 4HDO GNP 0.00003605 0.46645 12.5749
365 1GP2 GDP 0.0001341 0.46673 12.6761
366 2C5L GTP 0.00005866 0.45853 12.8205
367 2QN6 GDP 0.000005868 0.58377 12.9032
368 3BFV ADP 0.000000002682 0.73884 12.9825
369 5M04 GDP 0.000006778 0.44743 13.0556
370 1JI0 ATP 0.00008937 0.53181 13.3333
371 1J2J GTP 0.0001345 0.46668 13.3333
372 4ZNL BEF ADP 0.0001477 0.41978 13.5036
373 2C04 GCP 0.0001551 0.44273 13.6842
374 1RJ9 GCP 0.0000178 0.40151 13.6842
375 1IN4 ADP 0.0001983 0.44195 13.7725
376 1X1R GDP 0.00006934 0.45535 14.0449
377 3A4M ADP 0.000006469 0.44208 14.2308
378 2A9K GDP 0.00001071 0.48185 14.3498
379 1YQT ADP 0.00009384 0.53562 14.386
380 4DCT GDP 0.00001092 0.5546 14.7368
381 3KTA AP5 0.0001569 0.43723 15.0289
382 2ZJ5 ADP 0.009566 0.4285 15.4386
383 1D2E GDP 0.00001428 0.53538 16.1404
384 3PQC GDP 0.0001689 0.42393 16.4103
385 5L3R GCP 0.0000006768 0.5502 16.8421
386 2GCO GNP 0.00007979 0.44976 16.9154
387 2GCN GDP 0.0003612 0.44342 16.9154
388 2CK3 ADP 0.0002592 0.45496 17.1233
389 2CK3 ANP 0.0001619 0.44666 17.1233
390 2V7Q ADP 0.00004217 0.43048 17.1233
391 2V7Q ATP 0.0003509 0.4128 17.1233
392 1Z0K GTP 0.00009236 0.47339 17.3913
393 3QDK QDK 0.01103 0.43097 17.5439
394 2OFW ADX 0.0009763 0.45198 17.7885
395 1D5C GDP 0.00002524 0.51805 17.9012
396 1NF3 GNP 0.000346 0.43574 17.9688
397 3GJ4 GDP 0.00000647 0.45912 18.1818
398 2DPY ADP 0.0002812 0.50616 18.9474
399 3ZQ6 ADP ALF 0.0000000003329 0.65439 19.2982
400 2PEZ GGZ 0.002992 0.42343 20.6704
401 2PEZ DAT 0.002992 0.42343 20.6704
402 3VX3 ADP 0.00000001313 0.60525 31.8548
403 3KJI ADP 0.00002886 0.51889 35.4386
404 3FWY ADP 0.0000000002655 0.65584 37.193
405 4WZA ACP 0.00000005235 0.66704 41.7544
406 4WZA ADP 0.00000005235 0.66704 41.7544
407 1FP6 ADP 0.000000008011 0.59192 41.7544
408 2BEK ATP 0.000000004166 0.68487 42.1053
409 1R4A GNP 0.00003438 0.48269 43.1373
410 1ION ADP 0.0000000006623 0.74424 44.856
411 1UPT GTP 0.00007082 0.48278 45
412 1G3Q ADP 0.0000000003867 0.76721 49.3671
Pocket No.: 2; Query (leader) PDB : 5J1J; Ligand: ANP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5j1j.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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