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Receptor
PDB id Resolution Class Description Source Keywords
5JE0 1.55 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF BURKHOLDERIA GLUMAE TOXA WITH BOUND S- ADENOSYLHOMOCYSTEINE (SAH) AND 1,6-DIDEMETHYLTOXOFLAVIN BURKHOLDERIA GLUMAE N-METHYLTRANSFERASE S-ADENOSYLMETHIONINE (SAM) SUBSTRATE TRANSFERASE
Ref.: BURKHOLDERIA GLUMAE TOXA IS A DUAL-SPECIFICITY METHYLTRANSFERASE THAT CATALYZES THE LAST TWO STEPS TOXOFLAVIN BIOSYNTHESIS. BIOCHEMISTRY V. 55 2748 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AZ8 B:302;
A:302;
Valid;
Valid;
none;
none;
submit data
165.11 C5 H3 N5 O2 c1nc2...
SAH A:301;
B:301;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5JE0 1.55 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF BURKHOLDERIA GLUMAE TOXA WITH BOUND S- ADENOSYLHOMOCYSTEINE (SAH) AND 1,6-DIDEMETHYLTOXOFLAVIN BURKHOLDERIA GLUMAE N-METHYLTRANSFERASE S-ADENOSYLMETHIONINE (SAM) SUBSTRATE TRANSFERASE
Ref.: BURKHOLDERIA GLUMAE TOXA IS A DUAL-SPECIFICITY METHYLTRANSFERASE THAT CATALYZES THE LAST TWO STEPS TOXOFLAVIN BIOSYNTHESIS. BIOCHEMISTRY V. 55 2748 2016
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 5JE0 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5JE2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 5JDZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 5JDY - SAH C14 H20 N6 O5 S c1nc(c2c(n....
5 5JE5 - AZ9 C6 H5 N5 O2 CN1C(=O)c2....
6 5JE1 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 5JE3 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
8 5JE4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 237 families.
1 5JE0 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5JE2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 5JDZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 5JDY - SAH C14 H20 N6 O5 S c1nc(c2c(n....
5 5JE5 - AZ9 C6 H5 N5 O2 CN1C(=O)c2....
6 5JE1 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 5JE3 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
8 5JE4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 5JE0 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5JE2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 5JDZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 5JDY - SAH C14 H20 N6 O5 S c1nc(c2c(n....
5 5JE5 - AZ9 C6 H5 N5 O2 CN1C(=O)c2....
6 5JE1 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 5JE3 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
8 5JE4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AZ8; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 AZ8 1 1
2 AZ9 0.423077 0.788462
Ligand no: 2; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5JE0; Ligand: AZ8; Similar sites found with APoc: 521
This union binding pocket(no: 1) in the query (biounit: 5je0.bio2) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 1WUW TSU None
2 4TTQ ATP None
3 5TVI O8N None
4 5FTW SAH 1.21457
5 4XFR CIT 1.21457
6 3CGD COA 1.21457
7 3CGD NAD 1.21457
8 3CGD FAD 1.21457
9 4IF4 BEF 1.44231
10 1RSG FAD 1.61943
11 1YY5 FAD 1.61943
12 3ZG6 APR 1.61943
13 4RPL 3UC 1.61943
14 4RPL FAD 1.61943
15 6F7L FAD 1.61943
16 4IRP UDP 1.61943
17 6HOY TSN 1.61943
18 5UC4 83S 1.81818
19 1G60 SAM 2.02429
20 4MIG G3F 2.02429
21 2GK6 ADP 2.02429
22 3WMX NAD 2.02429
23 3P9C SAH 2.02429
24 1UAY ADN 2.06612
25 4F8L AES 2.06897
26 2HMT NAI 2.08333
27 1V6A TRE 2.10843
28 1TL2 NDG 2.11864
29 1JG3 ADN 2.12766
30 2WG9 OCA 2.30769
31 2VT3 ATP 2.32558
32 2EJU SAH 2.42915
33 3G89 SAM 2.42915
34 2EFJ SAH 2.42915
35 2EG5 SAH 2.42915
36 5HSS 64Z 2.42915
37 1ZQ9 SAM 2.42915
38 5C9P FUC 2.42915
39 5BUK FAD 2.42915
40 6ER9 FAD 2.42915
41 2IVD FAD 2.42915
42 3NJ4 AFX 2.42915
43 6ER9 NAP 2.42915
44 2UXR ICT 2.42915
45 3QVP FAD 2.42915
46 3GF4 FAD 2.42915
47 4POO SAM 2.5
48 3R51 MMA 2.5
49 2W3L DRO 2.77778
50 5XNC MTA 2.83401
51 3A27 SAM 2.83401
52 3EVF GTA 2.83401
53 5K7U SAM 2.83401
54 3EVF SAH 2.83401
55 3RKR NAP 2.83401
56 3GCZ SAM 2.83401
57 5ICE 2H4 2.83401
58 5IL1 SAM 2.83401
59 2PX8 SAH 2.83401
60 5BJX NAD 2.83401
61 5BJX UDP 2.83401
62 3HKA FIX 2.83401
63 5ICE SAH 2.83401
64 1BZL GCG 2.83401
65 2WPF FAD 2.83401
66 2WPF WPF 2.83401
67 5BVA FAD 2.83401
68 3FPZ AHZ 2.83401
69 5MBX FAD 2.83401
70 5MBX SP5 2.83401
71 4RP9 ASC 2.83401
72 3VYW SAM 2.83401
73 3CIF NAD 2.83401
74 4Z0H NAD 2.83401
75 4LEB THR THR THR THR THR THR THR 2.83401
76 4RSL FAD 2.83401
77 5W3Y ACO 2.83401
78 4IRX INS 2.83401
79 5O42 9JW 2.83401
80 5O42 NAD 2.83401
81 5O42 BGC 2.83401
82 1WDK NAD 2.83401
83 2JB2 PHE 2.83401
84 2JB2 FAD 2.83401
85 3V1Y NAD 2.83401
86 3G5S FAD 2.83401
87 3U4C NDP 2.83401
88 5ZZ6 ADP 2.88462
89 2IZ1 ATR 3.23887
90 3H8V ATP 3.23887
91 3M6W SAM 3.23887
92 2DPM SAM 3.23887
93 2WA2 SAM 3.23887
94 5L95 AMP 3.23887
95 1ELI PYC 3.23887
96 4ZCC NAI 3.23887
97 4ZCC FAD 3.23887
98 4BLW SAH 3.23887
99 4REP FAD 3.23887
100 1COY FAD 3.23887
101 4IPN 1FT 3.23887
102 4BLW AMP 3.23887
103 4YZ5 SLT 3.23887
104 5LD5 NAD 3.23887
105 2IV2 MGD 3.23887
106 1E6E FAD 3.23887
107 1E1M NAP 3.23887
108 1E1M FAD 3.23887
109 1COY AND 3.23887
110 1U1I NAD 3.23887
111 4JDR FAD 3.23887
112 2GV8 FAD 3.23887
113 5GT9 NAP 3.23887
114 2Q1S NAI 3.23887
115 2XYQ SAH 3.27869
116 3N8K D1X 3.48837
117 2UYQ SAM 3.64372
118 2JHP SAH 3.64372
119 1WG8 SAM 3.64372
120 1UWK NAD 3.64372
121 1UWK URO 3.64372
122 4MOP 2H5 3.64372
123 2YG3 FAD 3.64372
124 5GSN NAP 3.64372
125 5GSN FAD 3.64372
126 4X9M FAD 3.64372
127 3WGT FAD 3.64372
128 3WGT QSC 3.64372
129 5GSN MMZ 3.64372
130 2ZXI FAD 3.64372
131 1CER NAD 3.64372
132 6BR7 BEF 3.7594
133 3V78 ET 3.84615
134 1RJD SAM 3.89222
135 1V59 NAD 4.04858
136 4RDH AMP 4.04858
137 4D79 ATP 4.04858
138 4RDI ATP 4.04858
139 3NDJ SAH 4.04858
140 3NDJ JHZ 4.04858
141 3H5N ATP 4.04858
142 6BQ6 TER 4.04858
143 5Z75 NAD 4.04858
144 4EUE NAI 4.04858
145 2IID FAD 4.04858
146 2IID PHE 4.04858
147 2VVM FAD 4.04858
148 6BE0 COA 4.04858
149 4IV9 FAD 4.04858
150 2VVL FAD 4.04858
151 4NBW NAD 4.04858
152 1XKQ NDP 4.04858
153 1FEC FAD 4.04858
154 2F5Z FAD 4.04858
155 2BZ1 TAU 4.08163
156 2XB8 XNW 4.10959
157 3A3B RBF 4.21053
158 3A3B FMN 4.21053
159 1XCL SAH 4.25532
160 3ELW SAM 4.45344
161 3ELW GP3 4.45344
162 3O7W SAM 4.45344
163 5W7R SAH 4.45344
164 1NAA ABL 4.45344
165 1NAA 6FA 4.45344
166 1JQ3 AAT 4.45344
167 1I8T FAD 4.45344
168 4MO2 FDA 4.45344
169 3E1T FAD 4.45344
170 1PS9 FAD 4.45344
171 4MO2 FAD 4.45344
172 5VYQ TYD 4.45344
173 4N49 SAM 4.45344
174 3HDY FAD 4.45344
175 5W7R 9Z7 4.45344
176 3HDY GDU 4.45344
177 4UCI SAM 4.45344
178 3DXY SAM 4.58716
179 4XUC 43G 4.58716
180 4XUC SAM 4.58716
181 1JNR FAD 4.66667
182 4MN7 SME 4.69799
183 4F07 FAD 4.73684
184 1X14 NAD 4.73815
185 4DMG SAM 4.8583
186 2OBF SAH 4.8583
187 2OBF F83 4.8583
188 4YAC NAI 4.8583
189 3MB5 SAM 4.8583
190 4II2 ATP 4.8583
191 2PWY SAH 4.8583
192 3SSO SAH 4.8583
193 2A14 SAH 4.8583
194 1G55 SAH 4.8583
195 1P77 ATR 4.8583
196 3AYI FAD 4.8583
197 3AYI HCI 4.8583
198 1T36 ORN 4.8583
199 4B63 NAP 4.8583
200 4B63 ORN 4.8583
201 4B63 FAD 4.8583
202 2OZ5 7XY 4.8583
203 5VN0 FAD 4.8583
204 5VN0 NAI 4.8583
205 3UCL NAP 4.8583
206 3UCL CYH 4.8583
207 3UCL FAD 4.8583
208 3ET1 ET1 4.8583
209 1RRC ADP 4.8583
210 2VDV SAM 4.87805
211 1LSS NAD 5
212 1P1C SAH 5.02513
213 5JNW 6LJ 5.03145
214 2CJF RP4 5.09554
215 5CUQ NSC 5.26316
216 4M37 SAH 5.26316
217 3I53 SAH 5.26316
218 3FPF TNA 5.26316
219 2Q28 ADP 5.26316
220 3FPF MTA 5.26316
221 5JJR SAH 5.26316
222 4M38 SAH 5.26316
223 4X7Y SAH 5.26316
224 1DSS NAD 5.26316
225 3B1F NAD 5.26316
226 1UP7 NAD 5.26316
227 2C5A GDC 5.26316
228 2C5A NAD 5.26316
229 4LHD GLY 5.26316
230 2PK3 A2R 5.26316
231 5YJI SAH 5.66802
232 5YJI 8WO 5.66802
233 5THZ SAH 5.66802
234 5THY SAH 5.66802
235 1DL5 SAH 5.66802
236 3B12 FAH 5.66802
237 3FSY SCA 5.66802
238 2Z3Y F2N 5.66802
239 3A25 SAM 5.66802
240 5UR0 NAD 5.66802
241 3TKA SAM 5.66802
242 4YRY FAD 5.66802
243 4YDD MD1 5.66802
244 4YDD MGD 5.66802
245 1MUU NAD 5.66802
246 1MV8 NAD 5.66802
247 3WV8 ATP 5.9633
248 3FZG SAM 6
249 5ERG SAM 6.07287
250 4C01 QY9 6.07287
251 2XVL PXN 6.07287
252 3ABI NAD 6.07287
253 1OBB NAD 6.07287
254 5K4W NAI 6.07287
255 3GD4 NAD 6.07287
256 3GD4 FAD 6.07287
257 2RH1 CLR 6.07287
258 5K4W THR 6.07287
259 3KIH GDL 6.18557
260 4C4A SAH 6.35838
261 5AEW BNL 6.38298
262 3GWZ SAH 6.47773
263 3A4T SFG 6.47773
264 3GXO SAH 6.47773
265 3S1S SAH 6.47773
266 1VJT NAD 6.47773
267 3BGD PM6 6.47773
268 3BGD SAH 6.47773
269 3WSG CIT 6.47773
270 1QO8 FAD 6.47773
271 1OFZ FUL 6.47773
272 1OFZ FUC 6.47773
273 1PN0 FAD 6.47773
274 4FZV SAM 6.69456
275 5FRE SIA GAL 6.70103
276 2V73 SIA 6.80628
277 2CDU ADP 6.88259
278 1Q0S SAH 6.88259
279 5MW4 5JU 6.88259
280 3QOX SAH 6.88259
281 1LVL NAD 6.88259
282 1BRW URA 6.88259
283 2CDU FAD 6.88259
284 1GTE FAD 6.88259
285 4FN4 NAD 6.88259
286 3VSE SAH 6.88259
287 1J0X NAD 6.88259
288 4HA6 FAD 6.88259
289 6GAR FAD 6.88259
290 2HK9 ATR 6.90909
291 1O97 AMP 7.19697
292 1O97 FAD 7.19697
293 3HVJ 705 7.23982
294 1XDS SAM 7.28745
295 1QZZ SAM 7.28745
296 3ML1 MGD 7.28745
297 1BW9 NAD 7.28745
298 3ZDS OMD 7.28745
299 3QJ4 FAD 7.28745
300 3ZDS HMQ 7.28745
301 3IHG FAD 7.28745
302 5GWT SIN 7.28745
303 3OJO NAD 7.28745
304 5GWT NAD 7.28745
305 1PL6 NAD 7.28745
306 1SQL GUN 7.53425
307 5FA5 MTA 7.69231
308 4X60 3XV 7.69231
309 4X60 SFG 7.69231
310 4GQB 0XU 7.69231
311 6D6Y SAH 7.69231
312 3X0D SAH 7.69231
313 2FK8 SAM 7.69231
314 1BC5 SAH 7.69231
315 5YEC ATP 7.69231
316 3FUU ADN 7.69231
317 5WGR FAD 7.69231
318 5G3U ITW 7.69231
319 5G3U FDA 7.69231
320 4URF NAD 7.69231
321 5TTJ FAD 7.69231
322 4DSG FAD 7.69231
323 4DSG UDP 7.69231
324 3TKY SAH 7.69231
325 1GPE FAD 7.69231
326 2EWM NAD 7.69231
327 1EJ0 SAM 7.77778
328 5XLX SAH 8.09717
329 3DMH GMP 8.09717
330 2YX1 SFG 8.09717
331 3DMH SAM 8.09717
332 2NYA MGD 8.09717
333 5TWB FAD 8.09717
334 3X0V FAD 8.09717
335 1D4D FAD 8.09717
336 3K7M FAD 8.09717
337 3CBG SAH 8.18966
338 1R18 SAH 8.37004
339 5FUB SAH 8.50202
340 1ZEM NAD 8.50202
341 5JCM NAD 8.50202
342 5JCM FAD 8.50202
343 5JCM ISD 8.50202
344 3U31 NAD 8.50202
345 2ZWA SAH 8.50202
346 4CNK FAD 8.50202
347 2IS6 ADP 8.50202
348 3TVQ DQH 8.87574
349 4XQC 13D 8.90688
350 2ZJ5 ADP 8.90688
351 4XQC NAD 8.90688
352 1KYZ FER 8.90688
353 1KYZ SAH 8.90688
354 4FC7 NAP 8.90688
355 4FC7 COA 8.90688
356 4Q3S X7A 8.90688
357 3D3W NAP 9.01639
358 1PR9 NAP 9.01639
359 6ARJ BW4 9.31174
360 6ARJ SAH 9.31174
361 5DX0 SFG 9.31174
362 5DX1 SFG 9.31174
363 5DWQ SFG 9.31174
364 5DX8 SFG 9.31174
365 5DXA SFG 9.31174
366 5YF1 8V0 9.31174
367 2YVJ NAI 9.31174
368 2C7G FAD 9.31174
369 4UP3 NDP 9.31174
370 1RM0 D6P 9.31174
371 1RM0 NAI 9.31174
372 5YF1 SFG 9.31174
373 2C7G ODP 9.31174
374 3S5W FAD 9.31174
375 1RZ1 NAD 9.31677
376 1QAN SAH 9.42623
377 3C3Y SAH 9.70464
378 3AXB PRO 9.7166
379 3AXB FAD 9.7166
380 2RC8 DSN 9.7166
381 1WZ1 DNS 9.73451
382 3QV1 NAD 9.7561
383 1JQD SAH 10.1215
384 1JQD HSM 10.1215
385 4PIO SAH 10.1215
386 4PIO AVI 10.1215
387 2AOT SAH 10.1215
388 3ZNN 4WL 10.1215
389 3ZNN FAD 10.1215
390 1YQZ FAD 10.1215
391 3FGZ BEF 10.1562
392 5X62 SAH 10.5263
393 3PT9 SAH 10.5263
394 2O07 SPD 10.5263
395 2O07 MTA 10.5263
396 3ICT FAD 10.5263
397 3ICS FAD 10.5263
398 5JAQ NAI 10.5263
399 1I1N SAH 10.6195
400 5N53 8NB 10.7692
401 3MAG SAH 10.9312
402 3MCT SAH 10.9312
403 4FWE FAD 10.9312
404 1Y8Q ATP 10.9312
405 4CVN ADP 10.9489
406 3QUG GIX 11.1111
407 5DM1 5D7 11.336
408 5DM1 SAH 11.336
409 1KPG SAH 11.336
410 1KPH SAH 11.336
411 5MHB PBG 11.7284
412 3GEG NAD 11.7409
413 4J36 FAD 11.7409
414 3JWH SAH 11.9816
415 2GAG NAD 12.1212
416 2ZIF SAM 12.1457
417 4D7E FAD 12.1457
418 3C6K SPD 12.336
419 3C6K MTA 12.336
420 2BZG SAH 12.5
421 2P41 SAH 12.5506
422 3EVG SAH 12.5506
423 3GRU AMP 12.5506
424 1X87 NAD 12.5506
425 1H82 GZZ 12.5506
426 1N2X SAM 12.5506
427 1H82 FAD 12.5506
428 1G8K MGD 12.782
429 3KPE TM3 12.8205
430 3Q87 SAM 12.9412
431 5FWA J7C 12.9555
432 2RAB NAD 12.9555
433 1KYQ NAD 12.9555
434 2RAB FAD 12.9555
435 4YAG NAI 12.9555
436 3ZIA ADP 13.1148
437 1YXM ADE 13.3603
438 5DLY SAH 13.3603
439 5DLY 5D7 13.3603
440 1NV8 SAM 13.3603
441 1NV8 MEQ 13.3603
442 6FDF SAH 13.3603
443 4CQM NAP 13.9344
444 2V7Q ADP 14
445 1GXU 2HP 14.2857
446 3DUW SAH 14.3498
447 4Y30 SAH 14.5749
448 4Y30 49L 14.5749
449 2V3V MGD 14.5749
450 4DCM SAM 14.6667
451 2JK0 ASP 14.9798
452 5EEH P9P 15.1596
453 5EEH SAH 15.1596
454 3LCC SAH 15.3191
455 3GDH SAH 15.3527
456 4OBW SAM 15.3846
457 6GFK SAH 15.3846
458 6B92 SAH 15.3846
459 2JJQ SAH 15.7895
460 1KQF MGD 16.1943
461 5HJM MTA 16.5992
462 4ITU 1HS 16.5992
463 4ITU NAI 16.5992
464 4KXQ APR 16.6667
465 3FRH SAH 17.004
466 4AZW SAM 17.004
467 2XVM SAH 17.0854
468 2PT9 2MH 17.134
469 2PT9 S4M 17.134
470 3L9W AMP 17.4089
471 3L9W GSH 17.4089
472 3EGI ADP 17.9612
473 4YUW 4JU 18.2186
474 4YUW S4M 18.2186
475 6DUB SAH 18.4685
476 1WY7 SAH 18.8406
477 5WP4 SAH 19.0283
478 5MPT SAH 19.0283
479 3GU3 SAH 19.0283
480 5E8J SAH 19.4332
481 5E9W SAH 19.4332
482 3OFK SAH 19.4444
483 5ZW3 SAH 19.5556
484 5KOK S9T 19.8381
485 5KOK SAH 19.8381
486 5KOK R9T 19.8381
487 4HSU FAD 20
488 1IM8 SAI 20.082
489 3TLJ SAH 20.2429
490 1L1E SAH 20.2429
491 1NW5 SAM 20.2429
492 1U2Z SAH 20.6478
493 5W7M SAH 21.0526
494 5WP5 SAH 21.0526
495 4Y9D NAI 21.4575
496 2I7C AAT 21.4575
497 4R6W PC 21.8623
498 4R6W SAH 21.8623
499 2NXE SAM 21.8623
500 4ONQ SFG 21.8623
501 5E1M SAH 21.9917
502 5E1M PRO PRO LYS ARG ILE ALA 21.9917
503 1TPY SAH 22.6721
504 3G2O SAM 22.6721
505 1Z3C SA8 23.0769
506 4A6D SAM 23.4818
507 5W7K SAH 23.8866
508 1VE3 SAM 24.2291
509 4M73 SAH 24.2915
510 4M73 M72 24.2915
511 6GKV SAH 24.6964
512 4QTU SAM 25
513 5GWX SAM 25.1012
514 5GWX SAR 25.1012
515 3VC1 GST 26.3158
516 3VC1 SAH 26.3158
517 4GUS FAD 28.5714
518 5M58 SAH 29.1304
519 2PXX SAH 29.7674
520 4IWN GEK 30.5677
521 5MGZ SAH 32.2034
Pocket No.: 2; Query (leader) PDB : 5JE0; Ligand: SAH; Similar sites found with APoc: 521
This union binding pocket(no: 2) in the query (biounit: 5je0.bio2) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 1WUW TSU None
2 4TTQ ATP None
3 5TVI O8N None
4 5FTW SAH 1.21457
5 4XFR CIT 1.21457
6 3CGD COA 1.21457
7 3CGD NAD 1.21457
8 3CGD FAD 1.21457
9 4IF4 BEF 1.44231
10 1RSG FAD 1.61943
11 1YY5 FAD 1.61943
12 3ZG6 APR 1.61943
13 4RPL 3UC 1.61943
14 4RPL FAD 1.61943
15 6F7L FAD 1.61943
16 4IRP UDP 1.61943
17 6HOY TSN 1.61943
18 5UC4 83S 1.81818
19 1G60 SAM 2.02429
20 4MIG G3F 2.02429
21 2GK6 ADP 2.02429
22 3WMX NAD 2.02429
23 3P9C SAH 2.02429
24 1UAY ADN 2.06612
25 4F8L AES 2.06897
26 2HMT NAI 2.08333
27 1V6A TRE 2.10843
28 1TL2 NDG 2.11864
29 1JG3 ADN 2.12766
30 2WG9 OCA 2.30769
31 2VT3 ATP 2.32558
32 2EJU SAH 2.42915
33 3G89 SAM 2.42915
34 2EFJ SAH 2.42915
35 2EG5 SAH 2.42915
36 5HSS 64Z 2.42915
37 1ZQ9 SAM 2.42915
38 5C9P FUC 2.42915
39 5BUK FAD 2.42915
40 6ER9 FAD 2.42915
41 2IVD FAD 2.42915
42 3NJ4 AFX 2.42915
43 6ER9 NAP 2.42915
44 2UXR ICT 2.42915
45 3QVP FAD 2.42915
46 3GF4 FAD 2.42915
47 4POO SAM 2.5
48 3R51 MMA 2.5
49 2W3L DRO 2.77778
50 5XNC MTA 2.83401
51 3A27 SAM 2.83401
52 3EVF GTA 2.83401
53 5K7U SAM 2.83401
54 3EVF SAH 2.83401
55 3RKR NAP 2.83401
56 3GCZ SAM 2.83401
57 5ICE 2H4 2.83401
58 5IL1 SAM 2.83401
59 2PX8 SAH 2.83401
60 5BJX NAD 2.83401
61 5BJX UDP 2.83401
62 3HKA FIX 2.83401
63 5ICE SAH 2.83401
64 1BZL GCG 2.83401
65 2WPF FAD 2.83401
66 2WPF WPF 2.83401
67 5BVA FAD 2.83401
68 3FPZ AHZ 2.83401
69 5MBX FAD 2.83401
70 5MBX SP5 2.83401
71 4RP9 ASC 2.83401
72 3VYW SAM 2.83401
73 3CIF NAD 2.83401
74 4Z0H NAD 2.83401
75 4LEB THR THR THR THR THR THR THR 2.83401
76 4RSL FAD 2.83401
77 5W3Y ACO 2.83401
78 4IRX INS 2.83401
79 5O42 9JW 2.83401
80 5O42 NAD 2.83401
81 5O42 BGC 2.83401
82 1WDK NAD 2.83401
83 2JB2 PHE 2.83401
84 2JB2 FAD 2.83401
85 3V1Y NAD 2.83401
86 3G5S FAD 2.83401
87 3U4C NDP 2.83401
88 5ZZ6 ADP 2.88462
89 2IZ1 ATR 3.23887
90 3H8V ATP 3.23887
91 3M6W SAM 3.23887
92 2DPM SAM 3.23887
93 2WA2 SAM 3.23887
94 5L95 AMP 3.23887
95 1ELI PYC 3.23887
96 4ZCC NAI 3.23887
97 4ZCC FAD 3.23887
98 4BLW SAH 3.23887
99 4REP FAD 3.23887
100 1COY FAD 3.23887
101 4IPN 1FT 3.23887
102 4BLW AMP 3.23887
103 4YZ5 SLT 3.23887
104 5LD5 NAD 3.23887
105 2IV2 MGD 3.23887
106 1E6E FAD 3.23887
107 1E1M NAP 3.23887
108 1E1M FAD 3.23887
109 1COY AND 3.23887
110 1U1I NAD 3.23887
111 4JDR FAD 3.23887
112 2GV8 FAD 3.23887
113 5GT9 NAP 3.23887
114 2Q1S NAI 3.23887
115 2XYQ SAH 3.27869
116 3N8K D1X 3.48837
117 2UYQ SAM 3.64372
118 2JHP SAH 3.64372
119 1WG8 SAM 3.64372
120 1UWK NAD 3.64372
121 1UWK URO 3.64372
122 4MOP 2H5 3.64372
123 2YG3 FAD 3.64372
124 5GSN NAP 3.64372
125 5GSN FAD 3.64372
126 4X9M FAD 3.64372
127 3WGT FAD 3.64372
128 3WGT QSC 3.64372
129 5GSN MMZ 3.64372
130 2ZXI FAD 3.64372
131 1CER NAD 3.64372
132 6BR7 BEF 3.7594
133 3V78 ET 3.84615
134 1RJD SAM 3.89222
135 1V59 NAD 4.04858
136 4RDH AMP 4.04858
137 4D79 ATP 4.04858
138 4RDI ATP 4.04858
139 3NDJ SAH 4.04858
140 3NDJ JHZ 4.04858
141 3H5N ATP 4.04858
142 6BQ6 TER 4.04858
143 5Z75 NAD 4.04858
144 4EUE NAI 4.04858
145 2IID FAD 4.04858
146 2IID PHE 4.04858
147 2VVM FAD 4.04858
148 6BE0 COA 4.04858
149 4IV9 FAD 4.04858
150 2VVL FAD 4.04858
151 4NBW NAD 4.04858
152 1XKQ NDP 4.04858
153 1FEC FAD 4.04858
154 2F5Z FAD 4.04858
155 2BZ1 TAU 4.08163
156 2XB8 XNW 4.10959
157 3A3B RBF 4.21053
158 3A3B FMN 4.21053
159 1XCL SAH 4.25532
160 3ELW SAM 4.45344
161 3ELW GP3 4.45344
162 3O7W SAM 4.45344
163 5W7R SAH 4.45344
164 1NAA ABL 4.45344
165 1NAA 6FA 4.45344
166 1JQ3 AAT 4.45344
167 1I8T FAD 4.45344
168 4MO2 FDA 4.45344
169 3E1T FAD 4.45344
170 1PS9 FAD 4.45344
171 4MO2 FAD 4.45344
172 5VYQ TYD 4.45344
173 4N49 SAM 4.45344
174 3HDY FAD 4.45344
175 5W7R 9Z7 4.45344
176 3HDY GDU 4.45344
177 4UCI SAM 4.45344
178 3DXY SAM 4.58716
179 4XUC 43G 4.58716
180 4XUC SAM 4.58716
181 1JNR FAD 4.66667
182 4MN7 SME 4.69799
183 4F07 FAD 4.73684
184 1X14 NAD 4.73815
185 4DMG SAM 4.8583
186 2OBF SAH 4.8583
187 2OBF F83 4.8583
188 4YAC NAI 4.8583
189 3MB5 SAM 4.8583
190 4II2 ATP 4.8583
191 2PWY SAH 4.8583
192 3SSO SAH 4.8583
193 2A14 SAH 4.8583
194 1G55 SAH 4.8583
195 1P77 ATR 4.8583
196 3AYI FAD 4.8583
197 3AYI HCI 4.8583
198 1T36 ORN 4.8583
199 4B63 NAP 4.8583
200 4B63 ORN 4.8583
201 4B63 FAD 4.8583
202 2OZ5 7XY 4.8583
203 5VN0 FAD 4.8583
204 5VN0 NAI 4.8583
205 3UCL NAP 4.8583
206 3UCL CYH 4.8583
207 3UCL FAD 4.8583
208 3ET1 ET1 4.8583
209 1RRC ADP 4.8583
210 2VDV SAM 4.87805
211 1LSS NAD 5
212 1P1C SAH 5.02513
213 5JNW 6LJ 5.03145
214 2CJF RP4 5.09554
215 5CUQ NSC 5.26316
216 4M37 SAH 5.26316
217 3I53 SAH 5.26316
218 3FPF TNA 5.26316
219 2Q28 ADP 5.26316
220 3FPF MTA 5.26316
221 5JJR SAH 5.26316
222 4M38 SAH 5.26316
223 4X7Y SAH 5.26316
224 1DSS NAD 5.26316
225 3B1F NAD 5.26316
226 1UP7 NAD 5.26316
227 2C5A GDC 5.26316
228 2C5A NAD 5.26316
229 4LHD GLY 5.26316
230 2PK3 A2R 5.26316
231 5YJI SAH 5.66802
232 5YJI 8WO 5.66802
233 5THZ SAH 5.66802
234 5THY SAH 5.66802
235 1DL5 SAH 5.66802
236 3B12 FAH 5.66802
237 3FSY SCA 5.66802
238 2Z3Y F2N 5.66802
239 3A25 SAM 5.66802
240 5UR0 NAD 5.66802
241 3TKA SAM 5.66802
242 4YRY FAD 5.66802
243 4YDD MD1 5.66802
244 4YDD MGD 5.66802
245 1MUU NAD 5.66802
246 1MV8 NAD 5.66802
247 3WV8 ATP 5.9633
248 3FZG SAM 6
249 5ERG SAM 6.07287
250 4C01 QY9 6.07287
251 2XVL PXN 6.07287
252 3ABI NAD 6.07287
253 1OBB NAD 6.07287
254 5K4W NAI 6.07287
255 3GD4 NAD 6.07287
256 3GD4 FAD 6.07287
257 2RH1 CLR 6.07287
258 5K4W THR 6.07287
259 3KIH GDL 6.18557
260 4C4A SAH 6.35838
261 5AEW BNL 6.38298
262 3GWZ SAH 6.47773
263 3A4T SFG 6.47773
264 3GXO SAH 6.47773
265 3S1S SAH 6.47773
266 1VJT NAD 6.47773
267 3BGD PM6 6.47773
268 3BGD SAH 6.47773
269 3WSG CIT 6.47773
270 1QO8 FAD 6.47773
271 1OFZ FUL 6.47773
272 1OFZ FUC 6.47773
273 1PN0 FAD 6.47773
274 4FZV SAM 6.69456
275 5FRE SIA GAL 6.70103
276 2V73 SIA 6.80628
277 2CDU ADP 6.88259
278 1Q0S SAH 6.88259
279 5MW4 5JU 6.88259
280 3QOX SAH 6.88259
281 1LVL NAD 6.88259
282 1BRW URA 6.88259
283 2CDU FAD 6.88259
284 1GTE FAD 6.88259
285 4FN4 NAD 6.88259
286 3VSE SAH 6.88259
287 1J0X NAD 6.88259
288 4HA6 FAD 6.88259
289 6GAR FAD 6.88259
290 2HK9 ATR 6.90909
291 1O97 AMP 7.19697
292 1O97 FAD 7.19697
293 3HVJ 705 7.23982
294 1XDS SAM 7.28745
295 1QZZ SAM 7.28745
296 3ML1 MGD 7.28745
297 1BW9 NAD 7.28745
298 3ZDS OMD 7.28745
299 3QJ4 FAD 7.28745
300 3ZDS HMQ 7.28745
301 3IHG FAD 7.28745
302 5GWT SIN 7.28745
303 3OJO NAD 7.28745
304 5GWT NAD 7.28745
305 1PL6 NAD 7.28745
306 1SQL GUN 7.53425
307 5FA5 MTA 7.69231
308 4X60 3XV 7.69231
309 4X60 SFG 7.69231
310 4GQB 0XU 7.69231
311 6D6Y SAH 7.69231
312 3X0D SAH 7.69231
313 2FK8 SAM 7.69231
314 1BC5 SAH 7.69231
315 5YEC ATP 7.69231
316 3FUU ADN 7.69231
317 5WGR FAD 7.69231
318 5G3U ITW 7.69231
319 5G3U FDA 7.69231
320 4URF NAD 7.69231
321 5TTJ FAD 7.69231
322 4DSG FAD 7.69231
323 4DSG UDP 7.69231
324 3TKY SAH 7.69231
325 1GPE FAD 7.69231
326 2EWM NAD 7.69231
327 1EJ0 SAM 7.77778
328 5XLX SAH 8.09717
329 3DMH GMP 8.09717
330 2YX1 SFG 8.09717
331 3DMH SAM 8.09717
332 2NYA MGD 8.09717
333 5TWB FAD 8.09717
334 3X0V FAD 8.09717
335 1D4D FAD 8.09717
336 3K7M FAD 8.09717
337 3CBG SAH 8.18966
338 1R18 SAH 8.37004
339 5FUB SAH 8.50202
340 1ZEM NAD 8.50202
341 5JCM NAD 8.50202
342 5JCM FAD 8.50202
343 5JCM ISD 8.50202
344 3U31 NAD 8.50202
345 2ZWA SAH 8.50202
346 4CNK FAD 8.50202
347 2IS6 ADP 8.50202
348 3TVQ DQH 8.87574
349 4XQC 13D 8.90688
350 2ZJ5 ADP 8.90688
351 4XQC NAD 8.90688
352 1KYZ FER 8.90688
353 1KYZ SAH 8.90688
354 4FC7 NAP 8.90688
355 4FC7 COA 8.90688
356 4Q3S X7A 8.90688
357 3D3W NAP 9.01639
358 1PR9 NAP 9.01639
359 6ARJ BW4 9.31174
360 6ARJ SAH 9.31174
361 5DX0 SFG 9.31174
362 5DX1 SFG 9.31174
363 5DWQ SFG 9.31174
364 5DX8 SFG 9.31174
365 5DXA SFG 9.31174
366 5YF1 8V0 9.31174
367 2YVJ NAI 9.31174
368 2C7G FAD 9.31174
369 4UP3 NDP 9.31174
370 1RM0 D6P 9.31174
371 1RM0 NAI 9.31174
372 5YF1 SFG 9.31174
373 2C7G ODP 9.31174
374 3S5W FAD 9.31174
375 1RZ1 NAD 9.31677
376 1QAN SAH 9.42623
377 3C3Y SAH 9.70464
378 3AXB PRO 9.7166
379 3AXB FAD 9.7166
380 2RC8 DSN 9.7166
381 1WZ1 DNS 9.73451
382 3QV1 NAD 9.7561
383 1JQD SAH 10.1215
384 1JQD HSM 10.1215
385 4PIO SAH 10.1215
386 4PIO AVI 10.1215
387 2AOT SAH 10.1215
388 3ZNN 4WL 10.1215
389 3ZNN FAD 10.1215
390 1YQZ FAD 10.1215
391 3FGZ BEF 10.1562
392 5X62 SAH 10.5263
393 3PT9 SAH 10.5263
394 2O07 SPD 10.5263
395 2O07 MTA 10.5263
396 3ICT FAD 10.5263
397 3ICS FAD 10.5263
398 5JAQ NAI 10.5263
399 1I1N SAH 10.6195
400 5N53 8NB 10.7692
401 3MAG SAH 10.9312
402 3MCT SAH 10.9312
403 4FWE FAD 10.9312
404 1Y8Q ATP 10.9312
405 4CVN ADP 10.9489
406 3QUG GIX 11.1111
407 5DM1 5D7 11.336
408 5DM1 SAH 11.336
409 1KPG SAH 11.336
410 1KPH SAH 11.336
411 5MHB PBG 11.7284
412 3GEG NAD 11.7409
413 4J36 FAD 11.7409
414 3JWH SAH 11.9816
415 2GAG NAD 12.1212
416 2ZIF SAM 12.1457
417 4D7E FAD 12.1457
418 3C6K SPD 12.336
419 3C6K MTA 12.336
420 2BZG SAH 12.5
421 2P41 SAH 12.5506
422 3EVG SAH 12.5506
423 3GRU AMP 12.5506
424 1X87 NAD 12.5506
425 1H82 GZZ 12.5506
426 1N2X SAM 12.5506
427 1H82 FAD 12.5506
428 1G8K MGD 12.782
429 3KPE TM3 12.8205
430 3Q87 SAM 12.9412
431 5FWA J7C 12.9555
432 2RAB NAD 12.9555
433 1KYQ NAD 12.9555
434 2RAB FAD 12.9555
435 4YAG NAI 12.9555
436 3ZIA ADP 13.1148
437 1YXM ADE 13.3603
438 5DLY SAH 13.3603
439 5DLY 5D7 13.3603
440 1NV8 SAM 13.3603
441 1NV8 MEQ 13.3603
442 6FDF SAH 13.3603