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Receptor
PDB id Resolution Class Description Source Keywords
5JGL 2.28 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF GTMA IN COMPLEX WITH S-ADENOSYLMETHIONI ASPERGILLUS FUMIGATUS ASPERGILLUS FUMIGATUS METHYLTRANSFERASE S-ADENOSYLMETHIONIGLIOTOXIN RESISTANCE TRANSFERASE
Ref.: STRUCTURAL, MECHANISTIC AND FUNCTIONAL INSIGHT INTO GLIOTOXINBIS-THIOMETHYLATION INASPERGILLUS FUMIGATU OPEN BIOL V. 7 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM A:301;
B:301;
Valid;
Valid;
none;
none;
Kd = 12.48 uM
398.437 C15 H22 N6 O5 S C[S@@...
NA A:302;
B:302;
Invalid;
Invalid;
none;
none;
submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5JGL 2.28 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF GTMA IN COMPLEX WITH S-ADENOSYLMETHIONI ASPERGILLUS FUMIGATUS ASPERGILLUS FUMIGATUS METHYLTRANSFERASE S-ADENOSYLMETHIONIGLIOTOXIN RESISTANCE TRANSFERASE
Ref.: STRUCTURAL, MECHANISTIC AND FUNCTIONAL INSIGHT INTO GLIOTOXINBIS-THIOMETHYLATION INASPERGILLUS FUMIGATU OPEN BIOL V. 7 2017
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 5JGK Kd = 12.6 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5EGP - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 5JGL Kd = 12.48 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 237 families.
1 5JGK Kd = 12.6 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5EGP - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 5JGL Kd = 12.48 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 5JGK Kd = 12.6 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5EGP - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 5JGL Kd = 12.48 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
4 5W7M - SAH C14 H20 N6 O5 S c1nc(c2c(n....
5 5W7K - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 202
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 ADN 0.565789 0.773333
9 RAB 0.565789 0.773333
10 XYA 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 5AL 0.510417 0.743902
25 54H 0.510204 0.673913
26 VMS 0.510204 0.673913
27 0UM 0.51 0.857143
28 AMP 0.505747 0.707317
29 LMS 0.505747 0.666667
30 A 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 SON 0.5 0.746988
34 SSA 0.5 0.684783
35 6RE 0.5 0.78481
36 K15 0.5 0.883117
37 5AD 0.5 0.75
38 SRP 0.5 0.746988
39 LSS 0.49505 0.706522
40 CA0 0.494624 0.714286
41 A12 0.494505 0.705882
42 AP2 0.494505 0.705882
43 ME8 0.490385 0.841463
44 TSB 0.49 0.681319
45 53H 0.49 0.666667
46 DAL AMP 0.49 0.765432
47 5CA 0.49 0.684783
48 ACP 0.489362 0.694118
49 ADP 0.48913 0.690476
50 5AS 0.48913 0.648936
51 J7C 0.488889 0.772152
52 A2D 0.488889 0.690476
53 ZAS 0.488636 0.769231
54 9ZD 0.485149 0.729412
55 9ZA 0.485149 0.729412
56 8QN 0.485149 0.743902
57 GAP 0.484536 0.73494
58 AN2 0.483871 0.682353
59 A3S 0.483871 0.813333
60 A7D 0.483871 0.851351
61 GJV 0.483516 0.775
62 SRA 0.483146 0.694118
63 LAD 0.480769 0.752941
64 KAA 0.480769 0.698925
65 GSU 0.480769 0.722222
66 AMO 0.480392 0.746988
67 DSZ 0.480392 0.703297
68 52H 0.48 0.666667
69 M33 0.478723 0.722892
70 BA3 0.478261 0.690476
71 MAO 0.478261 0.82716
72 NEC 0.477778 0.75
73 AOC 0.477778 0.776316
74 DSH 0.477778 0.842105
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 NVA LMS 0.475728 0.736264
78 Y3J 0.47561 0.706667
79 G5A 0.474227 0.684783
80 A3T 0.473684 0.8
81 B4P 0.473118 0.690476
82 AP5 0.473118 0.690476
83 A3N 0.472527 0.766234
84 KB1 0.471698 0.833333
85 PRX 0.46875 0.73494
86 APC 0.46875 0.705882
87 AT4 0.468085 0.686047
88 PAJ 0.466019 0.712644
89 4AD 0.466019 0.759036
90 RBY 0.463918 0.72619
91 ADP PO3 0.463918 0.728395
92 ADV 0.463918 0.72619
93 ADX 0.463158 0.666667
94 MHZ 0.463158 0.82716
95 AU1 0.463158 0.674419
96 YAP 0.462963 0.738095
97 TXA 0.462264 0.72619
98 NB8 0.462264 0.72093
99 A3G 0.461538 0.802632
100 VRT 0.459184 0.842105
101 XAH 0.458716 0.715909
102 YSA 0.458716 0.684783
103 HEJ 0.458333 0.690476
104 50T 0.458333 0.682353
105 ATP 0.458333 0.690476
106 LEU LMS 0.457143 0.717391
107 7D7 0.45679 0.723684
108 KH3 0.455357 0.871795
109 ACQ 0.454545 0.694118
110 AR6 0.453608 0.710843
111 APR 0.453608 0.710843
112 AQP 0.453608 0.690476
113 5FA 0.453608 0.690476
114 NSS 0.451923 0.703297
115 FA5 0.449541 0.746988
116 A5D 0.44898 0.789474
117 AD9 0.44898 0.674419
118 AGS 0.44898 0.678161
119 SAP 0.44898 0.678161
120 PTJ 0.448598 0.72093
121 YLB 0.448276 0.758621
122 YLP 0.447368 0.738636
123 8X1 0.446602 0.680851
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 3AM 0.444444 0.674699
128 MYR AMP 0.444444 0.776471
129 OAD 0.443396 0.73494
130 2VA 0.443299 0.779221
131 S8M 0.442308 0.831169
132 OOB 0.442308 0.722892
133 TYR AMP 0.441441 0.759036
134 6YZ 0.441176 0.694118
135 ADP VO4 0.441176 0.702381
136 VO4 ADP 0.441176 0.702381
137 T99 0.44 0.686047
138 TAT 0.44 0.686047
139 ANP 0.44 0.674419
140 WAQ 0.439252 0.75
141 B5Y 0.436364 0.717647
142 8PZ 0.436364 0.684783
143 F0P 0.435897 0.844156
144 YLC 0.435897 0.755814
145 AAT 0.435644 0.797468
146 1ZZ 0.435185 0.755814
147 9K8 0.435185 0.663158
148 3OD 0.435185 0.73494
149 NVA 2AD 0.434343 0.855263
150 00A 0.433962 0.689655
151 DLL 0.433962 0.722892
152 ARG AMP 0.433628 0.727273
153 7MD 0.433628 0.715909
154 ATF 0.431373 0.666667
155 SO8 0.43 0.792208
156 3UK 0.429907 0.714286
157 A6D 0.429907 0.72619
158 9X8 0.429907 0.717647
159 F2R 0.429752 0.7
160 5SV 0.428571 0.741176
161 AMP DBH 0.428571 0.714286
162 TYM 0.42735 0.746988
163 WSA 0.42735 0.692308
164 9SN 0.427273 0.681818
165 AHZ 0.426087 0.755814
166 P5A 0.425926 0.691489
167 B5V 0.425926 0.705882
168 PR8 0.425926 0.744186
169 A A 0.425926 0.710843
170 3NZ 0.425926 0.807692
171 A1R 0.424528 0.709302
172 2A5 0.424242 0.674419
173 7MC 0.423729 0.719101
174 B5M 0.423423 0.717647
175 7D5 0.422222 0.658824
176 JB6 0.422018 0.709302
177 FYA 0.422018 0.722892
178 AYB 0.421488 0.75
179 A22 0.419048 0.682353
180 MAP 0.419048 0.659091
181 2AM 0.417582 0.666667
182 TAD 0.417391 0.712644
183 A3P 0.416667 0.686747
184 ADP BMA 0.416667 0.714286
185 25A 0.415094 0.690476
186 YLA 0.413223 0.719101
187 8Q2 0.411765 0.663158
188 A3R 0.411215 0.709302
189 ADQ 0.411215 0.694118
190 48N 0.410256 0.72093
191 0XU 0.41 0.824324
192 GA7 0.408696 0.72619
193 7D3 0.40625 0.643678
194 PAP 0.405941 0.678571
195 DQV 0.405172 0.702381
196 OVE 0.404255 0.662791
197 4UV 0.403509 0.697674
198 AF3 ADP 3PG 0.403361 0.712644
199 3AD 0.402299 0.783784
200 CMP 0.402062 0.691358
201 2BA 0.402062 0.682927
202 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5JGL; Ligand: SAM; Similar sites found with APoc: 483
This union binding pocket(no: 1) in the query (biounit: 5jgl.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 1WUW TSU None
2 5KAX RHQ None
3 1V59 FAD 1.03806
4 1V59 NAD 1.03806
5 1FK8 NAD 1.16732
6 4URF NAD 1.20968
7 5X62 SAH 1.38408
8 6BQ6 TER 1.38408
9 3QWI CUE 1.48148
10 3QWI NAP 1.48148
11 2JAH NDP 1.61943
12 2JAP NDP 1.61943
13 2AOT SAH 1.7301
14 1JQD SAH 1.7301
15 2EFJ SAH 1.7301
16 5EEH SAH 1.7301
17 5EEH P9P 1.7301
18 1JQD HSM 1.7301
19 5FEU NAP 1.7301
20 3O03 NAP 1.7301
21 2GMH FAD 1.7301
22 2DPM SAM 1.76056
23 3DUW SAH 1.79372
24 3A4T SFG 1.82482
25 3OFK SAH 1.85185
26 5FFF NAP 1.94553
27 5FFF 5XC 1.94553
28 3MB5 SAM 1.96078
29 4NBU NAI 2
30 1Z3C SA8 2.07612
31 2EG5 SAH 2.07612
32 4M37 SAH 2.07612
33 3PT9 SAH 2.07612
34 4M38 SAH 2.07612
35 4RPL 3UC 2.07612
36 4RPL FAD 2.07612
37 6EL3 NAP 2.07612
38 1V6A TRE 2.07612
39 1JQ3 AAT 2.07612
40 1YY5 FAD 2.07612
41 1RSG FAD 2.07612
42 3ICT FAD 2.07612
43 5VN0 FAD 2.07612
44 5VN0 NAI 2.07612
45 3EVF GTA 2.16606
46 3EVF SAH 2.16606
47 1BDB NAD 2.16606
48 1TZD ADP 2.18182
49 2ZAT NAP 2.30769
50 3TLJ SAH 2.42215
51 4Y30 49L 2.42215
52 4Y30 SAH 2.42215
53 4BLW AMP 2.42215
54 4BLW SAH 2.42215
55 3ELW GP3 2.42215
56 3ELW SAM 2.42215
57 5JJR SAH 2.42215
58 5Z75 NAD 2.42215
59 4J1Q NDP 2.42215
60 3V1U NAD 2.42215
61 3FSY SCA 2.42215
62 1Y8Q ATP 2.42215
63 2JB2 PHE 2.42215
64 2JB2 FAD 2.42215
65 5N5S NAP 2.42215
66 6F3M NAD 2.42215
67 4EUE NAI 2.42215
68 6FHO FAD 2.42215
69 1W8D NAP 2.42215
70 4Z24 FAD 2.42215
71 1W6U NAP 2.42215
72 1MXG ACR 2.42215
73 3CH6 NAP 2.44755
74 3CH6 311 2.44755
75 1RP0 AHZ 2.46479
76 3U4C NDP 2.4911
77 4K26 SFF 2.53623
78 4K26 NDP 2.53623
79 2PX8 SAH 2.60223
80 3RKR NAP 2.67176
81 3BGD SAH 2.69231
82 3BGD PM6 2.69231
83 3DMH GMP 2.76817
84 3DMH SAM 2.76817
85 5BJX NAD 2.76817
86 5BJX UDP 2.76817
87 2GN4 NDP 2.76817
88 2GN4 UD1 2.76817
89 4G5H NAP 2.76817
90 4G5H UD7 2.76817
91 2O07 SPD 2.76817
92 4Y9D NAI 2.76817
93 2O07 MTA 2.76817
94 4GLL NAD 2.76817
95 2CDU FAD 2.76817
96 3CGB FAD 2.76817
97 3GCZ SAM 2.83688
98 1QAN SAH 2.86885
99 1IM8 SAI 2.86885
100 2BD0 NAP 2.86885
101 2WA2 SAM 2.89855
102 1WY7 SAH 2.89855
103 4O0L NDP 2.90909
104 3LCC SAH 2.97872
105 1H5Q NAP 3.01887
106 1NFQ NAI 3.07692
107 2PWY SAH 3.10078
108 5THY SAH 3.11419
109 4M73 M72 3.11419
110 4M73 SAH 3.11419
111 3VC1 GST 3.11419
112 3VC1 SAH 3.11419
113 5THZ SAH 3.11419
114 5FUB SAH 3.11419
115 3TKY SAH 3.11419
116 3P9C SAH 3.11419
117 3GRU AMP 3.11419
118 4YAC NAI 3.11419
119 6F5W KG1 3.11419
120 1X87 NAD 3.11419
121 6DEN FAD 3.11419
122 6DEN TP9 3.11419
123 6DEN G8A 3.11419
124 3VYW SAM 3.11419
125 3GD4 FAD 3.11419
126 3GD4 NAD 3.11419
127 1ORR NAD 3.11419
128 1MUU NAD 3.11419
129 1MV8 NAD 3.11419
130 3S1S SAH 3.11419
131 4Q9N NAI 3.11419
132 2ZXI FAD 3.11419
133 1TPY SAH 3.13589
134 3G89 SAM 3.21285
135 3NUG NAD 3.23887
136 2VDV SAM 3.25203
137 1U2Z SAH 3.46021
138 2P41 SAH 3.46021
139 1NW5 SAM 3.46021
140 2EJU SAH 3.46021
141 5MLR NAP 3.46021
142 5MLR GRQ 3.46021
143 2VHW NAI 3.46021
144 4HXY NDP 3.46021
145 1PN0 IPH 3.46021
146 2JK0 ASP 3.46021
147 4N49 SAM 3.46021
148 2RGO FAD 3.46021
149 1PN0 FAD 3.46021
150 1Q9I FAD 3.46021
151 1Q9I TEO 3.46021
152 2Z48 A2G 3.46021
153 4O1M NAD 3.46021
154 3ZV6 NAD 3.55872
155 3ZV6 4HB 3.55872
156 4QED NAP 3.62903
157 3EVG SAH 3.63636
158 2AG5 NAD 3.65854
159 3DXY SAM 3.66972
160 6F9Q NAD 3.67647
161 1Q7B NAP 3.68852
162 5CUQ NSC 3.74532
163 1RJD SAM 3.80623
164 5WP5 SAH 3.80623
165 4A6D SAM 3.80623
166 3FPF TNA 3.80623
167 3WMX NAD 3.80623
168 3L9W AMP 3.80623
169 3FPF MTA 3.80623
170 3X0D SAH 3.80623
171 1KYZ SAH 3.80623
172 1RLZ NAD 3.80623
173 1KYZ FER 3.80623
174 2V6G NAP 3.80623
175 4DMG SAM 3.80623
176 3L9W GSH 3.80623
177 2PT9 2MH 3.80623
178 2PT9 S4M 3.80623
179 1KOL NAD 3.80623
180 3RUV ANP 3.80623
181 5C9P FUC 3.80623
182 1U7T TDT 3.83142
183 1WG8 SAM 3.85965
184 1NV8 MEQ 3.87324
185 1NV8 SAM 3.87324
186 5OOH NAP 3.8835
187 5OOH 9ZZ 3.8835
188 2I7C AAT 3.88693
189 2NXE SAM 3.93701
190 2Q46 NAP 3.95257
191 4POO SAM 4
192 5KXE 6Y2 4.11523
193 2ZWA SAH 4.15225
194 3GWZ SAH 4.15225
195 1G55 SAH 4.15225
196 4ONQ SFG 4.15225
197 3O7W SAM 4.15225
198 3GXO SAH 4.15225
199 1EK6 UPG 4.15225
200 1EK6 NAI 4.15225
201 4KGD TDP 4.15225
202 4KGD FAD 4.15225
203 3M6W SAM 4.15225
204 3CGD NAD 4.15225
205 1V8B NAD 4.15225
206 5BUK FAD 4.15225
207 4L2I FAD 4.18251
208 1ZQ9 SAM 4.21053
209 6CI9 NAP 4.2471
210 5OVK NDP 4.29688
211 4FN4 NAD 4.33071
212 4ZA2 NAD 4.34783
213 5O42 BGC 4.37956
214 5O42 NAD 4.37956
215 5O42 9JW 4.37956
216 1NM5 NAP 4.4335
217 1N2X SAM 4.49827
218 4AZW SAM 4.49827
219 3A4V NAD 4.49827
220 3A4V PYR 4.49827
221 3A25 SAM 4.49827
222 2E7Z MGD 4.49827
223 1I8T FAD 4.49827
224 2VVM FAD 4.49827
225 2VVL FAD 4.49827
226 3HVJ 705 4.52489
227 1UAY ADN 4.54545
228 3WDM ADN 4.5977
229 2AE2 PTO 4.61538
230 2AE2 NAP 4.61538
231 2PXX SAH 4.65116
232 4IWN GEK 4.80349
233 1O5I NAD 4.81928
234 1BC5 SAH 4.83271
235 3G2O SAM 4.84429
236 4DCM SAM 4.84429
237 5L2M 6ZY 4.84429
238 1V5F FAD 4.84429
239 1V5F TPP 4.84429
240 3H5N ATP 4.84429
241 3UCL FAD 4.84429
242 3UCL CYH 4.84429
243 3UCL NAP 4.84429
244 1UP7 NAD 4.84429
245 2GDZ NAD 4.86891
246 5WUW NAP 4.87805
247 5Z2L NDP 4.89796
248 1PR9 NAP 4.91803
249 3D3W NAP 4.91803
250 5GT9 NAP 4.94297
251 5YF1 8V0 4.97238
252 5YF1 SFG 4.97238
253 1E3W NAD 4.98084
254 1G60 SAM 5
255 1E6W NAD 5
256 1XG5 NAP 5.01792
257 4FC7 NAP 5.05415
258 4FC7 COA 5.05415
259 1AE1 NAP 5.12821
260 2ZIF SAM 5.19031
261 5FWA J7C 5.19031
262 4D5G FAD 5.19031
263 4D5G TPP 5.19031
264 5L13 6ZE 5.19031
265 3OND NAD 5.19031
266 3OND ADN 5.19031
267 1BXK NAD 5.19031
268 4RF2 NAP 5.19031
269 4GKV NAD 5.19031
270 1VL8 NAP 5.24345
271 5DLY 5D7 5.26316
272 5DLY SAH 5.26316
273 5GWX SAM 5.28169
274 5GWX SAR 5.28169
275 1G0N PHH 5.30035
276 1G0N NDP 5.30035
277 2A14 SAH 5.32319
278 3GDH SAH 5.39419
279 6DUB SAH 5.40541
280 4FZV SAM 5.43933
281 1JA9 NDP 5.47445
282 3FZG SAM 5.5
283 5THQ NDP 5.51471
284 5MW4 5JU 5.53633
285 3QOX SAH 5.53633
286 6B92 SAH 5.53633
287 2JHP SAH 5.53633
288 2UYQ SAM 5.53633
289 2ZJ1 ARJ 5.53633
290 2ZJ1 NAD 5.53633
291 4ZCC NAI 5.53633
292 4ZCC FAD 5.53633
293 1PS9 NAP 5.53633
294 2C5A NAD 5.53633
295 2C5A GDC 5.53633
296 1KPG SAH 5.57491
297 2EWM NAD 5.62249
298 6EJI UD2 5.63003
299 1FUT 2GP 5.66038
300 5ZW3 SAH 5.77778
301 1OAA OAA 5.79151
302 6HT0 GQ8 5.80645
303 3N8K D1X 5.81395
304 3ABI NAD 5.88235
305 6FDF SAH 5.88235
306 5XNC MTA 5.88235
307 1YBH FAD 5.88235
308 5M67 NAD 5.88235
309 5M67 ADE 5.88235
310 5Y1G NAD 5.88235
311 5Y1G AKB 5.88235
312 5M67 3D1 5.88235
313 5XFV FMN 5.88235
314 1NYT NAP 5.90406
315 1KPH SAH 5.92335
316 3GU3 SAH 5.98592
317 1IY8 NAD 5.99251
318 2BZG SAH 6.03448
319 2WCU FUC 6.04027
320 5EPO NAP 6.10687
321 1EJ0 SAM 6.11111
322 2RH4 EMO 6.13718
323 5K4W THR 6.22837
324 5K4W NAI 6.22837
325 4DSG FAD 6.22837
326 4DSG UDP 6.22837
327 5N0J FAD 6.22837
328 3RJ5 NAD 6.29921
329 3EGI ADP 6.31068
330 6GFK SAH 6.3745
331 2BGM NAJ 6.47482
332 3GEG NAD 6.47773
333 4CQM NAP 6.51341
334 5ICE SAH 6.57439
335 5ICE 2H4 6.57439
336 3EYA FAD 6.57439
337 2IV2 MGD 6.57439
338 3NYC IAR 6.57439
339 3NYC FAD 6.57439
340 5K0A FAD 6.57439
341 3KIF GDL 6.60377
342 3A27 SAM 6.61765
343 1I1N SAH 6.63717
344 1EFV AMP 6.66667
345 1EFV FAD 6.66667
346 3FRH SAH 6.71937
347 4XUC SAM 6.88073
348 4XUC 43G 6.88073
349 5W7R 9Z7 6.92042
350 5W7R SAH 6.92042
351 1UWK NAD 6.92042
352 1UWK URO 6.92042
353 3VSE SAH 6.92042
354 2C31 TZD 6.92042
355 2C31 ADP 6.92042
356 2WOX NDP 6.92042
357 3FUU ADN 7.01107
358 5K7U SAM 7.11111
359 5DM1 SAH 7.11611
360 5DM1 5D7 7.11611
361 5HJM MTA 7.26644
362 3KLJ FAD 7.26644
363 5EJ2 NAD 7.26644
364 3U31 NAD 7.26644
365 1V35 NAI 7.26644
366 2WSB NAD 7.48031
367 1R18 SAH 7.48899
368 1XKQ NDP 7.5
369 3SJU NDP 7.52688
370 2JJQ SAH 7.52941
371 5IL1 SAM 7.54717
372 2DT5 NAD 7.58294
373 2CFC NAD 7.6
374 1E5Q NDP 7.61246
375 1T9D PYD 7.61246
376 1T9D 1MM 7.61246
377 1T9D P25 7.61246
378 5WKC FAD 7.61246
379 1T9D FAD 7.61246
380 2OBF SAH 7.61246
381 2OBF F83 7.61246
382 4NBW NAD 7.7821
383 3VZS NAP 7.7821
384 1O97 FAD 7.95455
385 1O97 AMP 7.95455
386 4GQB 0XU 7.95848
387 4X60 3XV 7.95848
388 4X60 SFG 7.95848
389 2YX1 SFG 7.95848
390 5FA5 MTA 7.95848
391 2IZ1 ATR 7.95848
392 3C6K SPD 8.13648
393 3C6K MTA 8.13648
394 2XYQ SAH 8.19672
395 5WP4 SAH 8.3045
396 4PIO AVI 8.3045
397 4PIO SAH 8.3045
398 4YUW 4JU 8.3045
399 4YUW S4M 8.3045
400 3HB5 NAP 8.3045
401 5J5Z FAD 8.3045
402 4NBT NAD 8.33333
403 4LKK SIA GAL 8.33333
404 2HK9 ATR 8.36364
405 1GEG NAD 8.59375
406 5KOK R9T 8.65052
407 5KOK SAH 8.65052
408 5KOK S9T 8.65052
409 4C4A SAH 8.65052
410 4ITU NAI 8.65052
411 4ITU 1HS 8.65052
412 4IV9 FAD 8.65052
413 3TKA SAM 8.93372
414 4RSL FAD 8.99654
415 5M58 SAH 9.13043
416 5MGZ SAH 9.32203
417 6ARJ SAH 9.34256
418 6ARJ BW4 9.34256
419 5DXA SFG 9.34256
420 5DWQ SFG 9.34256
421 5DX8 SFG 9.34256
422 5DX1 SFG 9.34256
423 5DX0 SFG 9.34256
424 4MO2 FDA 9.34256
425 5XLX SAH 9.57447
426 1QZZ SAM 9.68858
427 1XDS SAM 9.68858
428 4YAG NAI 9.68858
429 2Q28 ADP 9.68858
430 3FXU TSU 9.68858
431 1KQF MGD 9.68858
432 5TVI O8N 9.78261
433 5YJI SAH 9.85915
434 5YJI 8WO 9.85915
435 1ZEM NAD 9.92366
436 2YY7 NAD 10.0346
437 5FTW SAH 10.1562
438 1JG3 ADN 10.2128
439 2FR1 NDP 10.3806
440 1Q0S SAH 10.4247
441 4LHD GLY 10.7266
442 5DF1 58X 10.7266
443 5DF1 NAP 10.7266
444 5BVA FAD 10.7266
445 4QTU SAM 11.0577
446 3JWH SAH 11.0599
447 1YXM ADE 11.0727
448 4UCI SAM 11.0727
449 5GWT NAD 11.5108
450 5GWT SIN 11.5108
451 3NDJ SAH 12.1107
452 3NDJ JHZ 12.1107
453 1SQL GUN 12.3288
454 3TN7 NJP 12.4514
455 5T2U NAP 13.3065
456 5ERG SAM 13.4948
457 2DTX BMA 14.0152
458 1XHL NDP 14.1414
459 3I53 SAH 14.1566
460 6GKV SAH 14.1869
461 5MPT SAH 15.917
462 6D6Y SAH 15.917
463 5JCA FAD 15.917
464 2HMT NAI 15.9722
465 1VE3 SAM 16.7401
466 3Q87 SAM 16.8
467 5E1M PRO PRO LYS ARG ILE ALA 17.0124
468 5E1M SAH 17.0124
469 3A28 NAD 17.4419
470 1LSS NAD 20
471 2FK8 SAM 20.0692
472 1DL5 SAH 20.4152
473 1L1E SAH 20.5575
474 5E9W SAH 20.7612
475 4D42 W0I 21.2766
476 4D42 NAP 21.2766
477 5E8J SAH 22.7273
478 4R6W PC 23.6434
479 4R6W SAH 23.6434
480 2XVM SAH 27.6382
481 4OBW SAM 28.7938
482 1XCL SAH 32.766
483 1P1C SAH 38.6935
Pocket No.: 2; Query (leader) PDB : 5JGL; Ligand: SAM; Similar sites found with APoc: 34
This union binding pocket(no: 2) in the query (biounit: 5jgl.bio2) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 5C2N NAG None
2 3SJ7 NDP 0.793651
3 3SSO SAH 1.03806
4 1XHC FAD 1.7301
5 4OPC PGT 2.07612
6 5G3U ITW 2.42215
7 1LNX URI 2.46914
8 1P77 ATR 2.94118
9 1TL2 NDG 2.9661
10 5BRT CH9 3.11419
11 5BRT FAD 3.11419
12 4G6I RS3 3.33333
13 2Z49 AMG 3.46021
14 1Z6Z NAP 3.46021
15 5U5G NAP 3.46021
16 1QO8 FAD 3.80623
17 5YEC ATP 4.20168
18 5HXI FAD 4.49827
19 5HXI 5HN 4.49827
20 1ZBQ NAD 4.49827
21 1XSE NDP 5.19031
22 3AYI FAD 5.53633
23 3AYI HCI 5.53633
24 3OID NDP 6.20155
25 1O5O U5P 6.33484
26 2Z3Y F2N 6.57439
27 1GZ6 NAI 6.92042
28 1YQZ FAD 6.92042
29 2IVF MGD 7.26644
30 5HJM HSL 7.26644
31 5WGR FAD 7.61246
32 4CS9 AMP 8.46561
33 4JNA FAD 9.11765
34 1ZK7 FAD 10.3806
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