Receptor
PDB id Resolution Class Description Source Keywords
5JZJ 1.71 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF DCLK1-KD IN COMPLEX WITH AMPPN HOMO SAPIENS KINASE DOUBLECORTIN TRANSFERASE
Ref.: BIOCHEMICAL AND STRUCTURAL INSIGHTS INTO DOUBLECORT KINASE DOMAIN 1. STRUCTURE V. 24 1550 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AN2 B:902;
A:703;
Valid;
Valid;
none;
none;
submit data
426.216 C10 H16 N6 O9 P2 c1nc(...
SO4 A:702;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
MG A:701;
B:901;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5JZJ 1.71 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF DCLK1-KD IN COMPLEX WITH AMPPN HOMO SAPIENS KINASE DOUBLECORTIN TRANSFERASE
Ref.: BIOCHEMICAL AND STRUCTURAL INSIGHTS INTO DOUBLECORT KINASE DOMAIN 1. STRUCTURE V. 24 1550 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 107 families.
1 5JZJ - AN2 C10 H16 N6 O9 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 82 families.
1 5JZJ - AN2 C10 H16 N6 O9 P2 c1nc(c2c(n....
50% Homology Family (492)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 2E9O ic50 = 20 nM A58 C25 H27 N3 O2 CC1CCC(CC1....
2 2WMQ - ZYQ C9 H11 N3 O2 S CC(=O)Nc1n....
3 2BRO ic50 = 1.4 uM DF2 C21 H20 N4 O2 c1ccc(cc1)....
4 2QHN ic50 = 980 nM 582 C13 H13 N3 O CCN1c2cccc....
5 4RVM ic50 = 1 nM 3X7 C23 H21 N5 c1cc(ccc1C....
6 5DLS ic50 = 4.4 nM 5CV C31 H34 N6 O3 CC(C)(CN(C....
7 3TKI ic50 = 0.05 nM S25 C20 H23 N7 O2 S c1cnc(cc1N....
8 2YM5 ic50 = 0.43 uM YM5 C18 H21 N5 O2 c1cc(cc(c1....
9 4HYH ic50 = 1 nM 1AM C22 H22 N6 O3 S COc1ccc2c(....
10 1NVS Ki = 15 nM UCM C24 H15 N3 O3 c1ccc2c(c1....
11 2YDK ic50 = 0.007 uM YDK C17 H20 N4 O2 S c1ccc(cc1)....
12 3OT3 ic50 = 0.005 uM 22K C16 H20 Br N7 Cn1cc(cn1)....
13 2HXQ ic50 = 144 nM 373 C24 H26 N4 O c1ccc2c(c1....
14 2QHM ic50 = 660 nM 7CS C16 H19 N3 O2 CN1[C@H]2C....
15 2BRH ic50 = 22 uM DFW C20 H15 N3 O3 c1ccc(cc1)....
16 2R0U ic50 = 1 nM M54 C25 H22 N4 O2 c1cc(cc(c1....
17 1NVR Ki = 7.8 nM STU C28 H26 N4 O3 C[C@@]12[C....
18 3OT8 ic50 = 0.009 uM MI5 C19 H22 N8 S Cc1cc(sn1)....
19 2YM4 ic50 = 1.5 uM 4YM C21 H22 N6 O3 CCOC(=O)c1....
20 4HYI ic50 = 2 nM 1AO C21 H20 N6 O S c1ccc2c(c1....
21 4RVL ic50 = 41.7 nM 3XL C17 H10 N4 O c1ccc(c(c1....
22 2XF0 ic50 = 30 uM 4UB C15 H11 N5 c1ccc(cc1)....
23 2YM6 ic50 = 0.88 uM YM6 C14 H16 N6 O c1cncc2c1c....
24 4QYG ic50 = 0.0041 uM 3DW C22 H21 N5 O2 CN1CCN(CC1....
25 3TKH ic50 = 47 nM 07S C23 H27 N7 O2 S c1cc(cnc1)....
26 2XEZ ic50 = 1.5 uM XEZ C12 H9 N7 c1c[nH]nc1....
27 2HXL ic50 = 12 nM 422 C23 H24 N6 c1cc2c(cc1....
28 5F4N ic50 = 2.2 nM 5UY C17 H19 N7 O3 COC(=O)c1c....
29 2C3J Ki = 0.659 uM DBQ C11 H11 N5 O2 c1c[nH]c2c....
30 2YM7 ic50 = 0.13 uM YM7 C15 H18 N8 c1c(ncnc1N....
31 2X8I ic50 = 0.19 uM X8I C17 H13 N3 O2 CC1=CC2=NN....
32 2YDJ ic50 = 0.005 uM YDJ C17 H19 F N4 O2 S c1cc(cc(c1....
33 4QYE ic50 = 1.2 uM 3DL C17 H12 N2 O3 c1cc(cc(c1....
34 2BRG ic50 = 6.1 uM DFY C21 H19 N3 O2 CN(CCO)c1c....
35 2CGU ic50 = 13.4 uM 3A3 C17 H13 N O7 c1cc-2c(cc....
36 2WMR ic50 = 52 uM ZYR C10 H10 N2 O S C1CCc2c(c3....
37 3PA5 ic50 = 2 nM C73 C17 H19 Cl N4 O2 S c1cc(ccc1c....
38 2WMV ic50 = 9.2 uM ZYV C10 H14 N6 O c1[nH]c2c(....
39 2CGX ic50 = 15.6 uM 3D3 C7 H8 N6 O S c1nc(c2c(n....
40 4QYF - 3DV C17 H13 N3 O3 c1cc(cc(c1....
41 3JVS Ki = 0.146 uM AGY C22 H22 N4 O4 CC(C)(C)c1....
42 2WMW ic50 = 0.39 uM ZYW C11 H14 Br N5 O c1c2c(c(cn....
43 2BR1 Ki = 7.2 uM PFP C22 H21 N3 O4 COc1ccc(cc....
44 2C3L Ki = 0.026 uM IDZ C14 H10 N4 c1ccc2c(c1....
45 2X8E ic50 = 0.014 uM X8E C16 H12 N4 O CC1=CC2=NN....
46 2X8D ic50 = 0.8 uM X8D C11 H9 N3 O CC1=CC2=NN....
47 2YEX ic50 = 0.0001 uM YEX C15 H12 N4 O CC1=CC2=NN....
48 2BRM Ki = 1.3 uM DFZ C20 H18 N4 O c1ccc(cc1)....
49 1NVQ Ki = 5.6 nM UCN C28 H26 N4 O4 C[C@@]12[C....
50 3PA4 ic50 = 3 nM C72 C19 H19 Cl N4 O S c1cc(ccc1c....
51 1JSV - U55 C10 H11 N5 O2 S c1cc(ccc1N....
52 1OIQ ic50 = 2.9 uM HDU C14 H13 N5 O Cc1c(n2ccc....
53 2W17 ic50 = 0.002 uM I19 C24 H30 F N7 O Cc1ncc(n1C....
54 2VTP ic50 = 0.003 uM LZ9 C17 H11 F3 N4 O2 c1cc(c(c(c....
55 1JVP ic50 = 1.6 uM LIG C15 H11 N3 c1ccc-2c(c....
56 1FVT - 106 C14 H9 Br N4 O3 S c1cc(ccc1/....
57 4KD1 - 1QK C21 H29 N6 O2 CCc1cnn2c1....
58 3LE6 ic50 = 0.035 uM 2BZ C17 H10 Cl N5 O2 Cc1c-2nc(c....
59 2VTI ic50 = 0.66 uM LZ3 C14 H12 N4 O3 S c1ccc2c(c1....
60 3LFS Ki = 2.5 uM A07 C17 H16 Cl N3 O CCCC(=O)Nc....
61 1PXI - CK1 C8 H5 Cl2 N3 S c1cnc(nc1c....
62 4LYN - 1YG C20 H23 N3 O2 S2 C[C@@H](c1....
63 1YKR ic50 = 0.56 uM 628 C20 H14 Cl2 N4 O3 S c1cc(c(c(c....
64 1PXN Ki ~ 0.32 uM CK6 C15 H15 N5 O S Cc1c(sc(n1....
65 2R3J ic50 = 10 nM SCJ C18 H14 Br N5 c1ccc(cc1)....
66 3IG7 ic50 = 9 nM EFP C18 H22 N4 O3 CC(=O)NC1C....
67 2VTS ic50 = 0.03 uM LZC C16 H23 N7 CC(C)Nc1cc....
68 1P2A ic50 = 12 nM 5BN C17 H15 F N4 O c1cc([nH]c....
69 2BHE ic50 = 1 uM BRY C16 H9 Br N2 O2 c1ccc2c(c1....
70 3UNK ic50 = 15 uM 0BY C17 H13 Cl N4 O2 c1ccc(c(c1....
71 2VTQ ic50 = 0.14 uM LZA C16 H17 F2 N5 O2 c1cc(c(c(c....
72 2C68 ic50 = 1.8 uM CT6 C18 H15 Br N5 c1cc(cc(c1....
73 3TIZ - 3TI C17 H13 N O2 c1ccc2c(c1....
74 3PXY ic50 = 5.9 uM JWS C10 H11 N5 O2 COc1ccc(c(....
75 2R3M ic50 = 10 nM SCX C19 H17 F2 N7 CCc1cnn2c1....
76 5JQ5 Kd = 2341 nM I74 C22 H30 N6 O CC(C)c1cnn....
77 2C6O - 4SP C18 H22 N6 O3 S c1cc(ccc1N....
78 1V1K Ki = 35 uM 3FP C22 H23 F4 N5 O2 CN(C)C[C@H....
79 2VTJ ic50 = 1.9 uM LZ4 C10 H9 Cl N4 O2 S c1cc(ccc1N....
80 3EZV - EZV C25 H25 N7 CN1CCN(CC1....
81 3PXZ Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
82 1W0X - OLO C15 H18 N6 O Cn1cnc2c1n....
83 2XMY Ki = 0.11 nM CDK C18 H21 N5 O4 S2 CC1=C(SC(=....
84 2UZO ic50 = 18 uM C62 C14 H10 N2 O5 S2 c1cc(ccc1c....
85 1KE7 ic50 = 8.9 nM LS3 C20 H15 N3 O4 S c1cc2c(cc1....
86 1DM2 - HMD C11 H10 Br N5 O2 C1CNC(=O)C....
87 1DI8 ic50 = 1 uM DTQ C16 H15 N3 O3 COc1cc2c(c....
88 5JQ8 - I73 C22 H30 N6 O CC(C)c1cnn....
89 1GIJ - 2PU C19 H22 N6 O2 c1cc2c(c(c....
90 2R3P ic50 = 900 nM 3SC C19 H12 Cl2 N6 S c1cc(c(c(c....
91 1KE8 ic50 = 1000 nM LS4 C18 H14 N4 O3 S2 c1ccc2c(c1....
92 2C6I ic50 = 11 uM DT1 C18 H22 N6 O3 S c1cc(ccc1N....
93 1PXP Ki ~ 0.22 uM CK8 C17 H19 N5 S Cc1c(sc(n1....
94 2UZN ic50 = 0.03 uM C96 C15 H13 N3 O4 S2 [H]/N=C/1N....
95 2B55 ic50 = 96 nM D31 C24 H31 N5 O2 c1cc-2c(c(....
96 5K4J - 6QB C21 H18 Cl F N6 O2 Cn1c(ccn1)....
97 3PJ8 - 404 C19 H26 N6 O CC[C@H](CO....
98 3LFQ - A28 C17 H15 F2 N3 O CCCC(=O)Nc....
99 2W05 ic50 = 0.001 uM FRT C20 H26 N6 O3 S Cc1ncc(n1C....
100 2XNB Ki = 149 nM Y8L C19 H22 N6 O S CC1=C(SC(=....
101 1HCK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
102 5IEX - 6AF C17 H21 Br N4 O3 S C[C@H]([C@....
103 2R3H ic50 = 20000 nM SCE C13 H13 N5 Cc1cnc2n1c....
104 3LFN Ki = 3160 nM A27 C23 H21 N3 O2 CCCC(=O)Nc....
105 3PY1 Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
106 2A4L ic50 = 0.4 uM RRC C19 H26 N6 O CC[C@H](CO....
107 1Y8Y ic50 = 2 uM CT7 C13 H11 Cl N4 O2 S CS(=O)(=O)....
108 1OIR ic50 = 0.032 uM HDY C23 H26 N6 O2 Cc1c(n2ccc....
109 1PXJ - CK2 C9 H10 N4 S Cc1c(sc(n1....
110 2VTO ic50 = 0.14 uM LZ8 C17 H13 F N4 O2 c1ccc(cc1)....
111 2BTR ic50 = 95 nM U73 C13 H15 N3 O S CC(C)C1=CN....
112 2VTA ic50 = 185 uM LZ1 C7 H6 N2 c1ccc2c(c1....
113 3EZR - EZR C26 H27 N7 O CN1CCN(CC1....
114 3ULI ic50 = 0.07 uM 1N3 C21 H25 Br N6 O2 COc1ccc(cc....
115 2DS1 ic50 = 6.4 nM 1CD C22 H21 N5 O3 C[C@@H]1C[....
116 5FP5 - 1Y6 C7 H5 F O2 c1cc(ccc1C....
117 2VTH ic50 = 120 uM LZ2 C10 H9 N O3 S c1cc2c(ccc....
118 1KE5 ic50 = 560 nM LS1 C16 H15 N3 O3 S CNS(=O)(=O....
119 3FZ1 - B98 C13 H15 N3 O2 S COc1ccc2c(....
120 1WCC ic50 = 350 uM CIG C4 H4 Cl N3 c1c(nc(cn1....
121 1E1V Ki = 12 uM CMG C12 H17 N5 O c1[nH]c2c(....
122 2VV9 ic50 = 0.017 uM IM9 C23 H29 N7 O2 Cc1ncc(n1C....
123 5IEV - R0N C18 H23 F3 N4 O3 S C[C@H]([C@....
124 4D1X - ESJ C11 H8 N2 O3 S2 c1cc2c(cc1....
125 2BTS ic50 = 20 nM U32 C12 H15 N3 O2 S2 CC(C)c1cnc....
126 1URW ic50 < 0.003 uM I1P C21 H24 N8 O2 S CN(C)CCCNS....
127 5FP6 - MFZ C11 H7 Cl2 N O c1cc(c2c(c....
128 1CKP - PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
129 1KE6 ic50 = 5.7 nM LS2 C17 H15 N5 O3 S2 CNS(=O)(=O....
130 2C6K ic50 = 0.73 uM DT2 C17 H21 N7 O2 S c1cc(ccc1N....
131 2R3Q - 5SC C19 H16 Br N5 O Cc1ccccc1c....
132 1OIT ic50 < 0.003 uM HDT C17 H14 N6 O2 S c1ccn2c(c1....
133 3NS9 ic50 = 0.003 uM NS9 C20 H27 N5 O3 CC(C)c1cnn....
134 1H01 ic50 = 22 uM FAL C21 H23 Cl2 N5 O2 CN(C)C[C@H....
135 2EXM - ZIP C10 H13 N5 CC(=CCNc1c....
136 4BGH ic50 = 4 nM 3I6 C13 H16 Br N5 O3 S C[C@H](CO)....
137 2R3F ic50 = 500 nM SC8 C18 H13 Cl2 N5 c1cc(c(c(c....
138 1GII - 1PU C17 H16 N4 O2 c1ccnc(c1)....
139 2R64 ic50 = 0.03 uM 740 C23 H27 N5 O3 S c1cc(ccc1C....
140 5A14 - LQ5 C24 H26 F3 N7 O2 CN1CCN(CC1....
141 2C6L ic50 = 0.27 uM DT4 C17 H22 N8 O2 S c1cc(ccc1N....
142 2W06 - FRV C18 H20 N6 O2 S Cc1ncc(n1C....
143 4EZ7 - STU C28 H26 N4 O3 C[C@@]12[C....
144 5D1J ic50 = 48 nM 56H C17 H24 N4 O2 S2 CC(C)(C)c1....
145 5IEY - 6AE C14 H19 N5 O3 S C[C@H]([C@....
146 2VTT ic50 = 0.044 uM LZD C16 H17 F2 N5 O2 c1cc(c(c(c....
147 2VU3 ic50 = 0.047 uM LZE C16 H17 Cl2 N5 O2 c1cc(c(c(c....
148 2B54 - D05 C20 H15 Cl3 N4 O3 CCc1c2c(n(....
149 1GZ8 - MBP C10 H13 N5 O2 CC(C)C(=O)....
150 3PY0 ic50 = 0.13 uM SU9 C13 H11 N3 O2 COc1ccc2c(....
151 2VTR ic50 = 1.5 uM LZB C10 H10 Cl N5 CC(C)Nc1cc....
152 1E1X Ki = 1.3 uM NW1 C11 H17 N5 O2 C1CCC(CC1)....
153 3UNJ ic50 = 11 uM 0BX C17 H14 N4 O2 c1ccc(cc1)....
154 2A0C - CK9 C19 H26 N6 O2 CC[C@H](CO....
155 3TIY - TIY C11 H8 O5 c1c2c(c(c(....
156 2R3I ic50 = 1000 nM SCF C18 H14 F N5 c1ccc(c(c1....
157 1VYZ ic50 = 290 nM N5B C13 H13 N3 O c1ccc(cc1)....
158 3WBL ic50 = 23 uM PDY C20 H26 N6 O CCOc1ccc(c....
159 4RJ3 ic50 = 93 nM 3QS C22 H28 N6 O COC1CCN(CC....
160 2VTN ic50 = 0.85 uM LZ7 C12 H11 F N4 O2 CC(=O)Nc1c....
161 1AQ1 - STU C28 H26 N4 O3 C[C@@]12[C....
162 2C6M ic50 = 0.35 uM DT5 C17 H20 N6 O3 S c1cc(ccc1N....
163 2R3L ic50 = 100 nM SCW C18 H14 Br N5 c1ccc(cc1)....
164 1H08 - BYP BWP n/a n/a
165 1B38 Kd = 0.254 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
166 2B52 ic50 = 8 nM D42 C21 H23 N7 O2 S Cc1c(sc(n1....
167 1PXL - CK4 C16 H13 F3 N4 S Cc1c(sc(n1....
168 3S2P ic50 = 0.068 uM PMU C17 H22 N4 O3 CC(C)c1cc(....
169 2R3O ic50 = 600 nM 2SC C19 H17 N5 O c1ccc(cc1)....
170 3IGG ic50 = 95 nM EFQ C16 H19 N3 O3 COc1ccc(cc....
171 1R78 ic50 = 3 nM FMD C20 H20 F N3 O4 C[C@H]([C@....
172 2FVD Ki = 0.003 uM LIA C18 H21 F2 N5 O4 S COc1ccc(c(....
173 2VTL ic50 = 97 uM LZ5 C10 H9 N3 O c1ccc(cc1)....
174 1KE9 ic50 = 660 nM LS5 C16 H15 N5 O3 S c1ccc2c(c1....
175 1PYE ic50 = 0.32 uM PM1 C21 H13 F2 N3 O2 c1ccc(cc1)....
176 4EZ3 - 0S0 C11 H10 N4 O4 S c1cc(ccc1/....
177 1H07 ic50 = 3 uM MFP C24 H27 Br N6 O2 Cc1ccc(c(c....
178 2B53 ic50 = 0.6 uM D23 C19 H19 F3 N4 CC(C)(C)Nc....
179 2DUV ic50 = 0.087 uM 371 C19 H17 N O7 S Cc1cc2c(c(....
180 4D1Z - WG8 C13 H10 N2 O3 S c1cc2ccc(n....
181 4ACM Ki = 210 nM 7YG C20 H23 N7 O3 S CN(C)CCNS(....
182 5LI9 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
183 3A8W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
184 3MB6 ic50 = 100 nM 01I C16 H8 O6 c1cc2c(cc(....
185 5M4F - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
186 5CVH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
187 3BQC ic50 ~ 2 uM EMO C15 H10 O5 Cc1cc2c(c(....
188 5CU2 - 54G C8 H8 O3 Cc1ccc(c(c....
189 5MO5 - 4IH C17 H21 Cl N2 O2 S CS(=O)(=O)....
190 5M4I - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
191 5MP8 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
192 5MOV - HC4 C9 H8 O3 c1cc(ccc1C....
193 5MOH - YTX C9 H10 O4 COc1cc(ccc....
194 5CSH Kd = 270 uM 54E C13 H12 Cl N c1ccc(cc1)....
195 3OWL ic50 = 0.67 uM 19E C16 H11 Cl N2 O Cc1cnc(c2c....
196 5H8G ic50 < 0.003 uM 5Y4 C23 H29 N9 O CC(=O)Nc1c....
197 5B0X ic50 = 0.02 uM HCK C18 H14 N2 O4 S COc1ccc(cc....
198 5MO8 Kd = 1.64 uM C98 C26 H26 Cl N3 O4 c1ccc(cc1)....
199 3AT4 Kd = 2.26 nM CCK C20 H20 N6 O2 CC(C)Nc1cc....
200 3OWJ Ki = 0.86 uM 1EL C17 H14 N2 O2 Cc1c2c(c(c....
201 5CU0 - 54R C18 H21 Cl N2 O CC(=O)NCCC....
202 5H8E ic50 < 0.003 uM 5Y3 C21 H25 N9 O CC(=O)Nc1c....
203 3WAR - NIO C6 H5 N O2 c1cc(cnc1)....
204 5MOE Kd = 500 uM OQC C11 H10 Cl N O c1cc(c(cc1....
205 4KWP Ki = 0.04 uM EXX C12 H10 Br4 N2 O3 c1nc2c(n1[....
206 5CSP Kd = 58 uM 54G C8 H8 O3 Cc1ccc(c(c....
207 5CTP - 54R C18 H21 Cl N2 O CC(=O)NCCC....
208 5MOW - BR9 C5 H6 Br N3 c1c(cnc(c1....
209 4UB7 Ki = 2.5 nM 3G5 C16 H8 Br2 O5 c1cc(ccc1C....
210 5MMF - JMB C16 H19 Cl N CCC[NH2+]C....
211 1PJK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
212 3NSZ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
213 3AXW - TID C9 H7 N3 O2 S c1cc(ccc1c....
214 5MO6 - KXZ C19 H21 Cl N2 O3 c1ccc(cc1)....
215 2PVR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
216 3C13 - EMO C15 H10 O5 Cc1cc2c(c(....
217 5CS6 Kd = 630 uM K82 C10 H14 Cl N O CCCOc1ccc(....
218 3PE2 Ki = 0.175 nM E1B C20 H12 N4 O2 C#Cc1cccc(....
219 5CT0 - 54P C16 H18 Cl N O c1ccc(cc1)....
220 5CU6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
221 5M4C - 7EY C16 H14 N2 O2 S2 Cc1ccc(cc1....
222 5MO7 - YRA C16 H17 Cl N2 O c1ccc(cc1)....
223 3OWK ic50 = 1.5 uM 18E C16 H11 Cl N2 O Cc1cnc(c2c....
224 5MMR - H83 C17 H21 Cl N2 c1ccc(cc1)....
225 5MPJ - J2P C15 H17 Cl N CC[NH2+]Cc....
226 5CSV - GAB C7 H7 N O2 c1cc(cc(c1....
227 5MOT - HBD C7 H7 N O2 c1cc(ccc1C....
228 3R0T ic50 = 0.91 nM FU9 C22 H16 F3 N5 O2 c1cc(cc(c1....
229 3PE1 Ki = 0.38 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
230 3JUH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
231 5CLP - 42J C8 H9 Cl2 N c1cc(c(cc1....
232 3H30 Ki = 29.2 uM RFZ C12 H12 Cl2 N2 O4 c1c2c(cc(c....
233 2ZJW ic50 = 0.04 uM REF C14 H6 O8 c1c2c-3c(c....
234 4GRB ic50 = 17 nM 0XG C19 H18 N4 O4 S CN(C)C(=O)....
235 3MB7 ic50 = 200 nM 14I C16 H8 O6 c1cc2c(cc(....
236 5CVF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
237 5CX9 - 551 C20 H23 Cl N2 O3 COC(=O)CC(....
238 3FHR - P4O C21 H16 N4 O c1ccc2c(c1....
239 3R1N - 05B C22 H21 N5 O3 c1cc2c(cc1....
240 3SHE - I85 C24 H22 F3 N5 O2 c1cc(cc(c1....
241 3BWJ ic50 = 2.6 uM ARX C28 H47 N15 O7 [H]/N=C(N)....
242 3AGL Ki = 16 nM A03 C37 H63 N17 O9 [H]/N=C(N)....
243 1RE8 Ki = 0.3 nM BD2 C27 H26 N2 O6 c1ccc(c(c1....
244 1REJ Ki = 5 nM B1L C20 H22 N2 O5 c1cc(ccc1C....
245 5IZJ - 6J9 C10 H13 N5 c1c[nH]c2c....
246 3AG9 Ki = 9 nM A02 C40 H70 N18 O9 [H]/N=C(N)....
247 5IZF Kd = 1.7 nM 6J9 AZ1 DAR ACA DAR NH2 n/a n/a
248 2VZ6 - FEF C20 H19 N3 O4 c1ccc2c(c1....
249 2Z7Q - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
250 2Z7R ic50 = 3 nM STU C28 H26 N4 O3 C[C@@]12[C....
251 4UZH ic50 = 9800 nM JVE C15 H13 F N4 O c1ccc(c(c1....
252 2C6E - HPM C28 H31 N7 O4 COc1cc2c(c....
253 3H0Y ic50 = 0.006 uM 48B C23 H17 Cl F N5 O2 c1ccc(c(c1....
254 4B0G ic50 = 0.015 uM VEK C19 H21 Br N8 O Cc1cc(no1)....
255 4JBP ic50 = 41 nM YPH C34 H36 N6 O4 c1ccc(cc1)....
256 3H10 - 97B C30 H25 Cl F2 N6 O CN1CCN(CC1....
257 1MQ4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
258 5EW9 Ki < 0.01 nM 5VC C22 H21 Cl F N3 O3 S c1cc(nc(c1....
259 4CEG - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
260 3DJ6 - AK6 C25 H24 N4 O3 S COc1ccc(cc....
261 2WQE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
262 3FDN ic50 = 0.033 uM MMH C21 H22 N6 O3 Cc1c(c([nH....
263 4J8M ic50 = 48 nM CJ5 C26 H25 F3 N8 O c1cc(cc(c1....
264 5DR9 - 5E2 C16 H9 Br Cl N O2 c1cc(cc(c1....
265 4DEA ic50 = 256 nM NHI C18 H14 N4 O4 c1cc(ccc1C....
266 5DN3 Kd = 3.77 uM 5DN C16 H9 Br F N O2 c1cc(cc(c1....
267 4DEE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
268 3UOD Kd = 49 nM 0C3 C18 H13 F3 N4 O2 c1ccc(c(c1....
269 3EFW - AK8 C25 H21 F3 N6 O2 Cc1cc(ccc1....
270 5DT0 - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
271 3UO4 Kd = 299 nM 0C0 C23 H18 N4 O2 c1ccc(cc1)....
272 3UP2 Kd = 40 nM 0C8 C18 H13 F3 N4 O3 c1ccc(c(c1....
273 5DR2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
274 3DJ5 - AK5 C21 H20 Br N5 O3 S COc1ccc(cc....
275 3UOL ic50 = 3.1 nM 0C7 C17 H13 Cl N8 c1ccc(c(c1....
276 3D14 ic50 = 22 nM AK1 C19 H15 F3 N6 O S2 c1cc(cc(c1....
277 4BN1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
278 2NP8 ic50 = 42 nM CC3 C21 H18 F3 N5 O c1cc(cc(c1....
279 4JBQ - VX6 C23 H28 N8 O S Cc1cc([nH]....
280 5DRD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
281 5DPV - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
282 4UYN ic50 = 2 nM Y3M C25 H22 N4 O4 S CCOC(=O)c1....
283 5DT3 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
284 2WTV Ki = 1.8 nM ZZL C25 H15 Cl F2 N4 O2 c1cc(c(c(c....
285 3O50 - LJE C24 H17 F3 N4 O2 Cc1cc(ccc1....
286 2J4Z ic50 = 65 nM 626 C23 H24 N6 O2 S CN1CCN(CC1....
287 3LAU ic50 = 0.044 uM OFI C17 H17 N3 O2 CCCC(=O)Nc....
288 3DAJ ic50 = 2.9 uM FXG C22 H29 N7 O2 CCCCNC(=O)....
289 4JBO ic50 = 24 nM WPH C31 H32 N6 O3 CN(C)CCOc1....
290 2C6D - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
291 4KS7 - X4Z C25 H28 N8 O S Cc1nc2ccsc....
292 1M2P - HNA C14 H7 N O6 c1cc2c(c(c....
293 1LPU - BEN C7 H8 N2 [H]/N=C(c1....
294 2QC6 ic50 = 0.1 uM G12 C10 H6 Br2 O3 CC1=C(C(=O....
295 4ANM ic50 = 28 nM WUL C15 H14 Br N3 O3 c1cc2c(cc1....
296 1DAW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
297 4RLK - E91 C21 H14 N2 O2 c1ccc2c(c1....
298 2OXD - K32 C7 H2 Br4 N2 O c12c(c(c(c....
299 2PVM Ki = 0.36 uM P29 C17 H15 N9 c1ccc(cc1)....
300 1J91 - TBS C6 H Br4 N3 c12c(c(c(c....
301 4DGO ic50 = 0.57 uM 0JW C10 H10 N2 O3 c1cc(c(cc1....
302 3FL5 - TXQ C14 H8 O6 c1cc(c(c2c....
303 3PWD ic50 = 0.22 uM CZ0 C14 H9 N O5 CC1=CC(=O)....
304 3KXH - K66 C11 H9 Br4 N3 O2 CN(C)c1nc2....
305 4DGM ic50 = 1.2 uM AGI C15 H10 O5 c1cc(ccc1C....
306 3PVG - K68 C9 H4 Br4 N2 O2 c1nc2c(n1C....
307 1ZOG Ki = 0.07 uM K37 C8 H4 Br4 N2 S CSc1[nH]c2....
308 2PVJ Ki = 0.005 uM P44 C19 H21 N7 c1ccc(cc1)....
309 4DGN ic50 = 0.35 uM LU2 C15 H10 O6 c1cc(c(cc1....
310 1M2Q - MNX C13 H7 N O6 c1cc(c2c(c....
311 2OXY - K17 C7 H2 Br4 N2 c1[nH]c2c(....
312 1M2R - MNY C14 H10 N2 O4 c1cc(c2c(c....
313 3KXN - K8X C7 H2 I4 N2 c1[nH]c2c(....
314 2PVL Ki = 0.024 uM P55 C18 H20 N8 CCN1CCN(CC....
315 1LP4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
316 2PVN Ki = 0.00035 uM P63 C20 H16 N8 O CC(=O)Nc1c....
317 3KXG - K6X C7 H Br5 N2 c12c(c(c(c....
318 3BE9 Ki = 24 nM P04 C19 H21 N7 O c1cc2cc(c1....
319 2OXX - K22 C7 H2 Br4 N2 S c12c(c(c(c....
320 3KXM - K74 C11 H9 Br4 N3 O S CNC(=O)CSc....
321 1LR4 - BEN C7 H8 N2 [H]/N=C(c1....
322 1OM1 Ki = 0.17 uM IQA C17 H12 N2 O3 c1ccc2c(c1....
323 1ZOH Ki = 0.1 uM K44 C10 H7 Br4 N3 C[N@@]1CCn....
324 2PVK Ki = 0.008 uM P45 C19 H14 Cl N7 c1ccc(cc1)....
325 1DAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
326 1JKL - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
327 3F5G - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
328 5AUZ ic50 = 98 uM GEN C15 H10 O5 c1cc(ccc1C....
329 1P4F - DRG C12 H11 N3 c1ccc-2c(c....
330 4TXC Kd = 0.24 uM 38G C24 H27 N5 O3 CN(C)CCN[C....
331 2YAK ic50 = 2 nM OSV C27 H31 F N4 O3 Ru S4 CC(C)Oc1cc....
332 5AUY ic50 = 1.6 uM MRI C15 H10 O7 c1cc(c(cc1....
333 3EH9 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
334 1IG1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
335 5AUW ic50 = 8.9 uM QUE C15 H10 O7 c1cc(c(cc1....
336 5AV2 - KMP C15 H10 O6 c1cc(ccc1C....
337 3EHA - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
338 5AV3 - KMP C15 H10 O6 c1cc(ccc1C....
339 5AUT Kd = 6.7 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
340 5AV0 ic50 = 280 uM 47X C15 H10 O5 c1cc(c(cc1....
341 1JKK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
342 3F5U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
343 5AV4 - GEN C15 H10 O5 c1cc(ccc1C....
344 5AUX ic50 = 10 uM KMP C15 H10 O6 c1cc(ccc1C....
345 5AUV ic50 = 31 uM AGI C15 H10 O5 c1cc(ccc1C....
346 2XK6 - EQH C18 H21 N3 O2 S c1csc(c1C2....
347 2WQO - VGK C21 H20 N2 O5 COc1cc(cc(....
348 2XKE ic50 = 4.2 uM WI2 C17 H20 N4 O3 COc1cccc(c....
349 2XNN - 430 C21 H16 F3 N3 O2 S C[C@H](c1c....
350 2XK7 ic50 = 1.5 uM 30E C21 H28 N4 O5 CC[C@H]1C[....
351 3QD4 ic50 = 0.00000001 M 3Q6 C22 H30 N8 O2 C[C@@H]1C[....
352 3RCJ ic50 = 0.8 uM 3RC C16 H13 N5 c1ccc(cc1)....
353 2PE0 - 39Z C14 H12 N2 O2 CC(c1ccc[n....
354 4CT2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
355 5ACK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
356 3HRC - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
357 5LVM - ADE C5 H5 N5 c1[nH]c2c(....
358 5MRD ic50 = 36.4 uM S26 C18 H13 Cl N2 O4 S2 CCOC(=O)C1....
359 3ION ic50 = 8 nM 8H1 C28 H27 N5 O3 COc1cc2c3c....
360 1UU7 ic50 = 14 uM BI2 C27 H26 N4 O2 C[N@@]1CCC....
361 3HRF Kd = 10.3 uM P47 C17 H15 Cl O2 c1ccc(cc1)....
362 3QCS ic50 = 0.00000001 M 3Q1 C15 H17 N7 O c1cc2c(cc1....
363 1H1W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
364 4AW1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
365 2PE2 - 464 C28 H30 N6 O3 c1cc(cc(c1....
366 3H9O ic50 = 70 nM 9BD C19 H19 N5 O3 COCCOc1cc2....
367 1Z5M ic50 = 30 nM LI8 C23 H31 Br N8 O3 CC(C)(C(=O....
368 5HKM ic50 = 0.013 uM 61Y C16 H15 N7 CCc1cc(nc(....
369 3QD0 ic50 = 0.00000001 M 3Q4 C24 H26 N8 O C[C@@H]1CC....
370 3ORZ - BI4 C27 H26 N4 O2 C[N@]1CCC[....
371 5LVN Kd = 20 uM ADN C10 H13 N5 O4 c1nc(c2c(n....
372 2XCH ic50 = 374 nM CKG C22 H25 N7 O c1c2c(nc(n....
373 4AW0 - MJF C18 H15 Cl O5 c1ccc(cc1)....
374 3OTU - BI4 C27 H26 N4 O2 C[N@]1CCC[....
375 3QCX ic50 = 0.00000001 M 3Q2 C16 H19 N7 O C[C@@H]1CO....
376 1UU3 ic50 = 0.75 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
377 5LVL Kd = 1.25 uM 537 C14 H8 N2 O c1ccc2c(c1....
378 3QC4 ic50 = 0.002 uM MP7 C28 H22 F2 N4 O4 c1ccc(cc1)....
379 3QCY ic50 = 0.00000001 M 3Q3 C22 H22 N8 O2 c1ccc(cc1)....
380 1UU8 ic50 = 9 uM BI1 C25 H24 N4 O2 CN(C)CCCn1....
381 4CT1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
382 4A07 - AZ7 C17 H13 Cl3 N2 O2 c1cc(ccc1[....
383 2JDO ic50 = 0.23 uM I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
384 1O6K - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
385 3E88 Ki = 2 nM G96 C24 H27 N7 O3 CCn1c2cc(n....
386 3D0E ic50 = 13 nM G93 C21 H27 N7 O3 CCn1c2c(cn....
387 2X39 ic50 = 30 nM X39 C19 H21 Cl N6 O c1cc(ccc1C....
388 3E87 - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
389 4QMP ic50 = 0.014 uM DKI C15 H13 F2 N7 O2 S2 c1cc(c(c(c....
390 4U8Z - 3FE C17 H15 N5 O c1cc(cc(c1....
391 4QMX ic50 = 11 uM H8H C27 H32 Cl N5 O5 CN1CCN(CC1....
392 4QMT ic50 = 0.01 uM H1N C29 H32 N4 O3 S CCS(=O)(=O....
393 4QMW ic50 = 0.086 uM KS1 C17 H17 N7 c1c[nH]c2c....
394 3A7H - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
395 4QML - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
396 4QO9 ic50 = 0.16 uM 627 C26 H30 N6 O3 CN1CCN(CC1....
397 4QMQ ic50 = 0.26 uM 34U C24 H27 N5 O2 COCCOc1ccc....
398 4NUS ic50 = 0.005 uM 2NK C22 H21 F2 N3 O CN1CCN(CC1....
399 4NW6 ic50 = 0.004 uM 2NS C23 H20 N4 O4 COc1cc(cc(....
400 4NW5 ic50 = 0.02 uM 2NR C23 H21 F N2 O5 COc1cccc(c....
401 4EL9 - AFE C21 H20 O10 C[C@H]1[C@....
402 5D9L ic50 = 0.024 uM 583 C15 H12 N2 O2 c1cc(ccc1c....
403 4FII - ARG PRO LYS PRO LEU VAL ASP PRO n/a n/a
404 4JDK - ARG ARG ARG ARG SER TRP TYR n/a n/a
405 2W7X ic50 = 138 nM D1A C18 H17 N7 O3 [H]/N=C(N)....
406 4A9U - A9U C27 H28 N4 O2 c1ccc(cc1)....
407 2YCF ic50 = 0.7 nM YCF C19 H24 N10 O3 [H]/N=C(N/....
408 4BDI ic50 = 227.7 uM HAU C14 H19 N3 O2 Cc1ccc(nc1....
409 2YCR ic50 = 69.6 nM HCW C23 H28 N10 O C/C(=NNC1=....
410 2WTJ ic50 = 0.7 uM WTJ C16 H20 N4 O3 S CN(C)CCNC(....
411 2YIT ic50 = 0.29 nM YIT C21 H24 N6 O2 CCC/C(=NNC....
412 2W0J ic50 = 240 nM ZAT C19 H24 N10 O [H]/N=C(N)....
413 2XK9 ic50 = 0.03 nM XK9 C18 H17 N7 O4 C/C(=NNC(=....
414 2YCS ic50 = 1.36 nM NXP C18 H18 N6 O C/C(=NNC(=....
415 2WTI ic50 = 0.092 uM WTI C18 H15 N3 O3 S c1cc(ccc1c....
416 2YIR ic50 = 0.17 nM YIR C20 H19 N7 O3 [H]/N=C(N)....
417 2XBJ ic50 = 0.86 uM XBJ C23 H27 F N4 O4 CC(C)([C@@....
418 2XM9 ic50 = 0.009 uM LWH C21 H20 N6 O c1ccc2c(c1....
419 2YIQ ic50 = 12.67 nM YIQ C20 H19 N7 O C/C(=NNC(=....
420 2CN5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
421 4FG9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
422 4FG8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
423 5L2T - 6ZZ C23 H30 N8 O CN(C)C(=O)....
424 5L2S - 6ZV C27 H32 F2 N8 CCN1CCN(CC....
425 4AUA ic50 = 7.2 uM 4AU C12 H9 N3 O c1ccc2c(c1....
426 2WEI ic50 = 3.4 nM VGG C17 H21 N5 Cc1cccc(c1....
427 3CQW ic50 = 42 nM CQW C12 H11 Cl N6 c1c(c2c([n....
428 4GV1 ic50 = 3 nM 0XZ C21 H25 Cl N6 O2 c1cc(ccc1[....
429 3MVH ic50 = 0.5 nM WFE C20 H22 F2 N6 O CCc1c[nH]c....
430 3MV5 ic50 = 180 nM XFE C11 H15 N5 Cc1c[nH]c2....
431 3QKL - SMR C29 H40 N4 O5 S CCOCC[N@@]....
432 3QKM ic50 = 0.038 uM SM9 C31 H43 N5 O4 S CCOCCN(C[C....
433 3CQU ic50 = 151 nM CQU C15 H13 N7 Cc1[nH]c(n....
434 3GC0 - AMP C10 H14 N5 O7 P c1nc(c2c(n....
435 3MFU - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
436 3C0H - AMP C10 H14 N5 O7 P c1nc(c2c(n....
437 3C0I - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
438 3MFS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
439 3C0G - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
440 3MFR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
441 4OTH ic50 = 9 nM DRN C25 H23 N5 O2 S [H]/N=C(/N....
442 4OTI ic50 = 43 nM MI1 C16 H20 N6 O C[C@@H]1CC....
443 4APP Ki = 0.064 uM N53 C33 H36 N6 O3 CC1(c2c(c(....
444 4NJD ic50 = 0.79 uM NJD C21 H20 N8 O COc1nc(nc(....
445 2YAB - AMP C10 H14 N5 O7 P c1nc(c2c(n....
446 2YAA - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
447 3A62 - STU C28 H26 N4 O3 C[C@@]12[C....
448 3WF9 ic50 = 567 nM FS7 C24 H25 N3 O5 S C[C@H]1CCc....
449 3WF8 ic50 = 232 nM F76 C23 H23 N3 O5 S c1ccc2c(c1....
450 4L3L - 5FI C19 H21 F3 N6 CCc1cncnc1....
451 3WE4 ic50 = 15 nM 5FI C19 H21 F3 N6 CCc1cncnc1....
452 3WF7 ic50 = 206 nM FS9 C18 H17 F3 N6 O c1cc(cc(c1....
453 4L3J - 5FI C19 H21 F3 N6 CCc1cncnc1....
454 3WF6 ic50 = 33 nM FZ9 C18 H16 N6 c1ccc2c(c1....
455 4AU8 ic50 = 551 nM Z3R C11 H8 N2 O2 S3 c1ccc2c(c1....
456 4O0R Ki = 0.036 uM X4Z C25 H28 N8 O S Cc1nc2ccsc....
457 5IME Ki = 4.6 nM 6BZ C22 H22 Cl N7 O2 CC1=NC=CN(....
458 4ZY6 Ki = 5 nM 4T6 C18 H17 Cl N8 c1cc2c(c(c....
459 3Q53 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
460 4EQC ic50 = 0.008 uM XR1 C29 H28 Cl N7 O S CCN1c2c(cn....
461 5JZJ - AN2 C10 H16 N6 O9 P2 c1nc(c2c(n....
462 5AX9 ic50 = 8 nM 4KT C24 H24 N4 O3 COc1ccc(cc....
463 4EQU - G6I C30 H24 F3 N7 O2 Cc1ccc(cc1....
464 4JR7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
465 4JQE - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
466 4MWH - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
467 4LFI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
468 3GGF - GVD C22 H19 N7 c1ccc2c(c1....
469 4OBQ ic50 = 0.065 uM 2QT C20 H20 F N5 O c1cc2c(cc1....
470 4U43 Kd = 48 uM 3D8 C11 H9 N5 c1cc(cnc1)....
471 3DAK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
472 1QL6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
473 1PHK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
474 5F9E ic50 = 0.46 nM 5VS C23 H21 N5 O2 CC1(NC(=O)....
475 1XJD Ki = 0.33 nM STU C28 H26 N4 O3 C[C@@]12[C....
476 3M2W ic50 < 0.003 uM L8I C23 H21 F N4 O CN1CC2(C1)....
477 3BHY - 7CP C18 H18 Cl2 N4 O Cn1c2c(ccc....
478 2J90 - IZA C18 H16 F N3 O CC(C)(C)c1....
479 5DBX - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
480 2VN9 - GVD C22 H19 N7 c1ccc2c(c1....
481 4EJN ic50 = 0.005 uM 0R4 C33 H26 F N7 O2 CC(=O)Nc1c....
482 4WNO ic50 = 160 nM 3RF C20 H19 N7 c1ccc2c(c1....
483 4WNP ic50 = 8 nM 3RJ C22 H20 N8 c1ccc2c(c1....
484 5CI7 ic50 = 120 nM 51W C18 H24 I N7 O c1cc(cc(c1....
485 5M56 - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
486 5M4U - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
487 3OFM - 4B0 C9 H7 Br4 N3 O C(Cn1c2c(c....
488 2V7O - DRN C25 H23 N5 O2 S [H]/N=C(/N....
489 3TXO ic50 = 9 nM 07U C17 H19 N5 CC(C)(CNc1....
490 4USF - 6UI C19 H15 N3 O COc1ccc2cc....
491 1V0P ic50 = 0.13 uM PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
492 1V0O ic50 = 5.5 uM INR C16 H10 N2 O5 S c1ccc2c(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AN2; Similar ligands found: 394
No: Ligand ECFP6 Tc MDL keys Tc
1 AN2 1 1
2 A2D 0.882353 0.958333
3 BA3 0.857143 0.958333
4 B4P 0.84507 0.958333
5 AP5 0.84507 0.958333
6 ADP 0.84507 0.985915
7 M33 0.821918 0.945205
8 AGS 0.813333 0.933333
9 SAP 0.813333 0.933333
10 ACP 0.810811 0.958904
11 ATP 0.810811 0.985915
12 APR 0.8 0.958333
13 5FA 0.8 0.985915
14 AQP 0.8 0.985915
15 AR6 0.8 0.958333
16 AD9 0.789474 0.958904
17 AMP 0.785714 0.957747
18 A 0.785714 0.957747
19 ADX 0.773333 0.8625
20 CA0 0.773333 0.932432
21 ACQ 0.769231 0.958904
22 ANP 0.769231 0.986111
23 50T 0.763158 0.945205
24 ABM 0.753425 0.905405
25 PRX 0.753247 0.881579
26 ATF 0.75 0.945946
27 A22 0.743902 0.972222
28 AMP MG 0.739726 0.88
29 5AL 0.7375 0.918919
30 AP2 0.733333 0.945946
31 A12 0.733333 0.945946
32 ADQ 0.72619 0.932432
33 A1R 0.72619 0.896104
34 SRA 0.726027 0.906667
35 SRP 0.719512 0.894737
36 OAD 0.709302 0.932432
37 APC 0.708861 0.945946
38 AU1 0.705128 0.986111
39 ADP MG 0.705128 0.893333
40 TAT 0.703704 0.945946
41 ADP BEF 0.696203 0.87013
42 BEF ADP 0.696203 0.87013
43 8QN 0.694118 0.918919
44 25A 0.694118 0.958333
45 3OD 0.693182 0.932432
46 AMO 0.686047 0.92
47 25L 0.685393 0.972222
48 ADP PO3 0.679012 0.930556
49 RBY 0.679012 0.92
50 ADV 0.679012 0.92
51 AHX 0.678161 0.909091
52 00A 0.678161 0.871795
53 5SV 0.674419 0.8375
54 OOB 0.674419 0.918919
55 BIS 0.674157 0.921053
56 ATP MG 0.670732 0.893333
57 PAJ 0.666667 0.873418
58 4AD 0.666667 0.907895
59 LAD 0.662921 0.85
60 DLL 0.659091 0.918919
61 ME8 0.655556 0.829268
62 FYA 0.655556 0.893333
63 NB8 0.655556 0.909091
64 3UK 0.651685 0.906667
65 SON 0.65 0.92
66 ALF ADP 0.647059 0.858974
67 ADP ALF 0.647059 0.858974
68 WAQ 0.644444 0.871795
69 PR8 0.644444 0.839506
70 MAP 0.643678 0.959459
71 GAP 0.642857 0.881579
72 AFH 0.642105 0.873418
73 ANP MG 0.639535 0.907895
74 ADP VO4 0.639535 0.918919
75 VO4 ADP 0.639535 0.918919
76 RAB 0.637681 0.833333
77 XYA 0.637681 0.833333
78 ADN 0.637681 0.833333
79 1ZZ 0.637363 0.829268
80 TXA 0.637363 0.92
81 PTJ 0.637363 0.884615
82 FA5 0.634409 0.894737
83 YAP 0.634409 0.883117
84 G3A 0.631579 0.909091
85 XAH 0.62766 0.851852
86 2A5 0.626506 0.906667
87 G5P 0.625 0.909091
88 9SN 0.623656 0.860759
89 ATR 0.619048 0.957747
90 PAP 0.619048 0.971831
91 GTA 0.618557 0.875
92 ADP BMA 0.615385 0.906667
93 7D3 0.6125 0.893333
94 OMR 0.61 0.841463
95 AOC 0.607595 0.810811
96 DAL AMP 0.606742 0.893333
97 48N 0.606061 0.884615
98 4UV 0.604167 0.883117
99 7D4 0.60241 0.893333
100 UP5 0.6 0.907895
101 NAI 0.6 0.896104
102 DND 0.6 0.92
103 NXX 0.6 0.92
104 TXD 0.6 0.896104
105 6V0 0.6 0.884615
106 NAX 0.6 0.8625
107 5AS 0.597561 0.790698
108 5N5 0.597222 0.808219
109 LAQ 0.59596 0.829268
110 A2R 0.595506 0.972222
111 TXE 0.594059 0.896104
112 4UU 0.591837 0.883117
113 AR6 AR6 0.591837 0.905405
114 A A 0.591398 0.931507
115 YLP 0.59 0.809524
116 5CD 0.589041 0.794521
117 A4D 0.589041 0.808219
118 AP0 0.588235 0.884615
119 4TC 0.588235 0.884615
120 YLC 0.588235 0.829268
121 A3P 0.585366 0.957747
122 JB6 0.585106 0.871795
123 7D5 0.584416 0.866667
124 ITT 0.583333 0.930556
125 ATP A A A 0.583333 0.917808
126 A4P 0.582524 0.833333
127 TYM 0.578431 0.894737
128 UPA 0.572816 0.896104
129 YLB 0.572816 0.809524
130 139 0.571429 0.8625
131 T5A 0.571429 0.831325
132 ADJ 0.571429 0.841463
133 COD 0.570093 0.802326
134 3AM 0.56962 0.916667
135 4UW 0.568627 0.85
136 A2P 0.566265 0.943662
137 CNA 0.566038 0.92
138 EP4 0.565789 0.74359
139 MYR AMP 0.5625 0.807229
140 IOT 0.561905 0.821429
141 PPS 0.561798 0.8625
142 M2T 0.558442 0.725
143 DTA 0.558442 0.776316
144 3DH 0.556962 0.763158
145 G5A 0.556818 0.790698
146 YLA 0.556604 0.809524
147 A5A 0.555556 0.819277
148 NAD 0.555556 0.918919
149 TSB 0.554348 0.831325
150 AYB 0.551402 0.8
151 MTA 0.551282 0.763158
152 V3L 0.550562 0.958333
153 SSA 0.549451 0.811765
154 AHZ 0.54902 0.807229
155 NA7 0.547368 0.945946
156 A3D 0.545455 0.906667
157 TYR AMP 0.545455 0.87013
158 7MD 0.544554 0.875
159 6AD 0.544444 0.897436
160 VMS 0.543478 0.8
161 54H 0.543478 0.8
162 AMP DBH 0.54 0.881579
163 TAD 0.539216 0.873418
164 53H 0.537634 0.790698
165 5CA 0.537634 0.811765
166 2AM 0.5375 0.930556
167 6RE 0.536585 0.75
168 LPA AMP 0.528846 0.807229
169 GNH 0.527473 0.921053
170 BTX 0.527273 0.831325
171 52H 0.526882 0.790698
172 NAE 0.526316 0.883117
173 DSZ 0.526316 0.811765
174 LSS 0.526316 0.772727
175 ZAS 0.52439 0.779221
176 IMO 0.52381 0.916667
177 J7C 0.52381 0.759494
178 A3N 0.52381 0.776316
179 5X8 0.522727 0.753247
180 BT5 0.522523 0.821429
181 NAQ 0.521739 0.860759
182 AV2 0.521739 0.905405
183 ARU 0.520833 0.85
184 ARG AMP 0.519231 0.819277
185 ALF ADP 3PG 0.518868 0.82716
186 LA8 ALF 3PG 0.518868 0.82716
187 AF3 ADP 3PG 0.518868 0.82716
188 OVE 0.518072 0.893333
189 S4M 0.517647 0.659091
190 YLY 0.517544 0.8
191 ZID 0.517241 0.906667
192 3AT 0.516484 0.958333
193 AVV 0.515789 0.884615
194 DSH 0.511905 0.716049
195 MAO 0.511628 0.771084
196 NSS 0.510417 0.811765
197 P5A 0.510204 0.755556
198 KAA 0.510204 0.764045
199 GSU 0.510204 0.790698
200 DZD 0.508929 0.873418
201 EAD 0.508475 0.8625
202 SFG 0.505618 0.74026
203 DAT 0.505618 0.893333
204 NVA LMS 0.505155 0.772727
205 NAD IBO 0.504505 0.858974
206 M24 0.504348 0.8625
207 N0B 0.504274 0.809524
208 DTP 0.5 0.893333
209 7DD 0.5 0.971831
210 GJV 0.5 0.740741
211 LEU LMS 0.5 0.772727
212 7MC 0.5 0.853659
213 YSA 0.5 0.790698
214 5AD 0.5 0.736111
215 NAJ PZO 0.5 0.860759
216 NDC 0.495935 0.860759
217 EEM 0.494624 0.682353
218 SA8 0.494505 0.698795
219 7D7 0.493333 0.733333
220 NDE 0.491803 0.92
221 P1H 0.491803 0.841463
222 NJP 0.491071 0.933333
223 SAI 0.48913 0.725
224 SAH 0.48913 0.734177
225 0WD 0.486726 0.909091
226 G A A A 0.486726 0.860759
227 4TA 0.486726 0.797619
228 PO4 PO4 A A A A PO4 0.484848 0.890411
229 S7M 0.484211 0.682353
230 SMM 0.484211 0.678161
231 FB0 0.483871 0.795455
232 SAM 0.483871 0.682353
233 7DT 0.483516 0.971831
234 A7D 0.483146 0.766234
235 NAJ PYZ 0.483051 0.8625
236 A5D 0.478261 0.776316
237 ODP 0.477876 0.897436
238 MHZ 0.477778 0.709302
239 71V 0.477273 0.896104
240 A3G 0.476744 0.789474
241 NEC 0.476744 0.736842
242 FDA 0.47619 0.823529
243 Y3J 0.474359 0.716216
244 GGZ 0.474227 0.814815
245 NPW 0.473214 0.875
246 NDP 0.473214 0.909091
247 6C6 0.473118 0.87013
248 6FA 0.472441 0.831325
249 A A A 0.47 0.893333
250 AMZ 0.46988 0.90411
251 C2R 0.46988 0.891892
252 U A G G 0.469565 0.871795
253 TXP 0.469027 0.909091
254 NZQ 0.469027 0.897436
255 6IA 0.468085 0.82716
256 DDS 0.468085 0.866667
257 A3S 0.466667 0.8
258 FAS 0.465116 0.841463
259 SFD 0.465116 0.744681
260 FAD 0.465116 0.841463
261 WSA 0.463636 0.8
262 AAT 0.463158 0.698795
263 7C5 0.462264 0.807692
264 62F 0.462121 0.851852
265 PGS 0.461538 0.871795
266 RGT 0.461538 0.945946
267 DA 0.45977 0.866667
268 D5M 0.45977 0.866667
269 NIA 0.458824 0.835443
270 2SA 0.458333 0.92
271 2VA 0.456522 0.789474
272 A3T 0.456522 0.810811
273 AMP NAD 0.454545 0.87013
274 GEK 0.454545 0.728395
275 AAM 0.454545 0.957747
276 4YB 0.453704 0.772727
277 FNK 0.451128 0.795455
278 Z5A 0.45082 0.790698
279 0UM 0.45 0.690476
280 XNP 0.448276 0.8625
281 FAY 0.447761 0.851852
282 62X 0.445545 0.659091
283 N6P 0.445545 0.902778
284 DCA 0.445378 0.813953
285 ETB 0.445378 0.823529
286 AIR 0.444444 0.888889
287 RFL 0.444444 0.811765
288 NAP 0.442623 0.932432
289 A U 0.442478 0.858974
290 APU 0.442478 0.883117
291 VRT 0.442105 0.759494
292 SO8 0.442105 0.779221
293 GP3 0.442105 0.909091
294 PUA 0.441667 0.873418
295 128 0.441441 0.788235
296 A6D 0.441176 0.73494
297 K15 0.441176 0.674419
298 NAD CJ3 0.440298 0.823529
299 6K6 0.44 0.917808
300 S8M 0.44 0.772152
301 V1N 0.439252 0.905405
302 TAP 0.439024 0.896104
303 0T1 0.438017 0.813953
304 COA 0.438017 0.813953
305 649 0.4375 0.755556
306 GDP 0.4375 0.907895
307 12D 0.436364 0.797619
308 NAD BBN 0.43609 0.853659
309 NA0 0.435484 0.92
310 GCP 0.434343 0.884615
311 3AD 0.432099 0.794521
312 101 0.431818 0.866667
313 GSP 0.43 0.8625
314 KB1 0.428571 0.690476
315 AMX 0.427419 0.823529
316 CAO 0.427419 0.786517
317 1DG 0.427419 0.909091
318 DG1 0.427419 0.909091
319 COS 0.427419 0.795455
320 30N 0.427419 0.744681
321 7RP 0.426966 0.915493
322 26A 0.426829 0.753247
323 FA9 0.426573 0.853659
324 P5F 0.425532 0.813953
325 N01 0.425 0.893333
326 GTP 0.424242 0.907895
327 CMX 0.424 0.813953
328 SCO 0.424 0.813953
329 NMN AMP PO4 0.423729 0.858974
330 NHD 0.423729 0.893333
331 7RA 0.422222 0.944444
332 AS 0.422222 0.822785
333 ACO 0.420635 0.786517
334 FAM 0.420635 0.795455
335 FCX 0.420635 0.786517
336 ACK 0.420455 0.849315
337 QQY 0.420455 0.805195
338 G1R 0.42 0.896104
339 F2N 0.41958 0.804598
340 SXZ 0.419048 0.702381
341 1VU 0.418605 0.786517
342 CC5 0.417722 0.805556
343 8BR 0.417582 0.894737
344 HAX 0.417323 0.816092
345 PLP AAD 0.416667 0.752809
346 GDD 0.416667 0.873418
347 GDC 0.416667 0.873418
348 GKE 0.416667 0.873418
349 J7V 0.416 0.823529
350 GNP 0.415842 0.909091
351 D3Y 0.415842 0.779221
352 2MC 0.415385 0.76087
353 TM1 0.415094 0.785714
354 3KK 0.414062 0.795455
355 FYN 0.414062 0.813953
356 U G A 0.413534 0.829268
357 CMP 0.413043 0.888889
358 2BA 0.413043 0.902778
359 SOP 0.410853 0.795455
360 MCD 0.410853 0.795455
361 OXK 0.410853 0.795455
362 CA6 0.410853 0.721649
363 COK 0.410853 0.795455
364 2FA 0.409639 0.802632
365 ENQ 0.409524 0.90411
366 3NZ 0.409524 0.772152
367 COO 0.409091 0.795455
368 QQX 0.409091 0.794872
369 CO6 0.407692 0.795455
370 CMC 0.407692 0.795455
371 NMX 0.407692 0.771739
372 CNV FAD 0.407143 0.784091
373 RMB 0.406593 0.861111
374 FAI 0.406593 0.90411
375 ANZ 0.405405 0.790123
376 NFD 0.404959 0.871795
377 CAJ 0.40458 0.795455
378 SCD 0.40458 0.813953
379 SP1 0.404494 0.831169
380 RP1 0.404494 0.831169
381 FAD NBT 0.404255 0.76087
382 NVA 2AD 0.402062 0.734177
383 IDP 0.402062 0.906667
384 KH3 0.401786 0.666667
385 SLU 0.401639 0.781609
386 U A C C 0.401639 0.848101
387 3HC 0.401515 0.804598
388 MLC 0.401515 0.795455
389 1HE 0.401515 0.777778
390 IVC 0.401515 0.804598
391 BCO 0.401515 0.795455
392 A1S 0.401515 0.795455
393 G 0.4 0.894737
394 5GP 0.4 0.894737
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5JZJ; Ligand: AN2; Similar sites found: 300
This union binding pocket(no: 1) in the query (biounit: 5jzj.bio2) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5MW8 ATP 0.0000001138 0.63111 1.6835
2 1RZ1 NAD 0.01613 0.40355 1.86335
3 2YRX AMP 0.008165 0.42299 2.0202
4 4UWH JXM 0.004664 0.41505 2.0202
5 1EHI ADP 0.004028 0.40356 2.0202
6 4R78 AMP 0.00009087 0.51214 2.3569
7 3X01 AMP 0.0009649 0.47087 2.3569
8 1Z03 OCH 0.01868 0.40326 2.3569
9 1CBK ROI 0.01823 0.40551 2.5
10 1SU2 ATP 0.00433 0.41459 2.51572
11 2GQS ADP 0.0004998 0.45402 2.53165
12 2GQR ADP 0.0005652 0.45166 2.53165
13 2GQS C2R 0.001064 0.44417 2.53165
14 5LRT ADP 0.009775 0.40908 2.55906
15 4XBT 3ZQ 0.01167 0.40072 2.58065
16 5G41 AP5 0.03695 0.40108 2.69058
17 2PYW ADP 0.000004144 0.55478 2.6936
18 4OCJ NDG 0.00005532 0.53114 2.6936
19 3I0O ADP 0.000479 0.47086 2.6936
20 2VPQ ANP 0.0004066 0.46902 2.6936
21 5MRH Q9Z 0.0008608 0.46443 2.6936
22 4U98 ACP 0.001752 0.42989 2.6936
23 1VRP IOM 0.004796 0.42542 2.6936
24 3DNT ATP 0.0005868 0.41767 2.6936
25 3VSV XYS 0.01431 0.41189 2.6936
26 4YNM SAM 0.005023 0.41171 2.6936
27 4JD3 COA 0.02525 0.40847 2.6936
28 3NRR D16 0.0353 0.40444 2.6936
29 3TY5 ATP 0.002882 0.40256 2.6936
30 2V58 LZJ 0.001167 0.47412 3.0303
31 5VZ0 ADP 0.0001845 0.47319 3.0303
32 4OCV ANP 0.00008 0.47301 3.0303
33 3WVR AMP 0.0004219 0.46238 3.0303
34 5C1P ADP 0.003011 0.41096 3.0303
35 5C1P DAL DAL 0.01011 0.4084 3.0303
36 3E7S AT2 0.02094 0.40081 3.0303
37 3NZ1 3NY 0.02317 0.40315 3.06513
38 2DKN NAI 0.01368 0.40781 3.13725
39 2CFC NAD 0.01124 0.41184 3.2
40 4XMF HSM 0.00007822 0.52858 3.26087
41 2CM4 RCL 0.01095 0.40201 3.33333
42 2VQD AP2 0.0002453 0.44533 3.367
43 3VOT ADP 0.001776 0.44376 3.367
44 3ETH ATP 0.002759 0.42926 3.367
45 4RPL 3UC 0.03245 0.41803 3.367
46 5ENQ 5QE 0.009751 0.40912 3.367
47 4J1Q NDP 0.0144 0.40546 3.367
48 4LH7 1X8 0.0223 0.40406 3.367
49 1IY8 NAD 0.01732 0.40541 3.37079
50 5TH5 MET 0.0185 0.40348 3.42205
51 2PUL ACP 0.000442 0.48897 3.7037
52 2IF8 ADP 0.0001434 0.44033 3.7037
53 2CFM AMP 0.01085 0.40624 3.7037
54 1F0X FAD 0.02527 0.40486 3.7037
55 5CPR 539 0.01753 0.40033 3.73134
56 4MNS 2AX 0.02652 0.41068 3.77358
57 1OBD ATP 0.000133 0.4638 4.0404
58 1F52 ADP 0.004117 0.4218 4.0404
59 4FE2 ADP 0.002312 0.43345 4.31373
60 4FE2 AIR 0.003896 0.4275 4.31373
61 2W9S TOP 0.02029 0.40144 4.34783
62 3V4S ATP 0.007815 0.40869 4.3771
63 1FQK ALF 0.01756 0.40728 4.3771
64 1JJE BYS 0.007035 0.40899 4.5045
65 5A5W GUO 0.004045 0.44465 4.74308
66 1M0W ANP 0.002762 0.41701 5.05051
67 4FHD EEM 0.009489 0.41784 5.38721
68 4FHD 0TT 0.009489 0.41784 5.38721
69 1T3Q FAD 0.01613 0.41341 5.38721
70 2QK4 ATP 0.002243 0.40765 5.38721
71 5GZ9 ANP 0.00000000008292 0.77424 5.72391
72 4ZS4 ATP 0.00000233 0.53622 5.72391
73 3PDT ADP 0.000008731 0.52598 5.72391
74 3TII ANP 0.004981 0.42241 5.72391
75 1N62 FAD 0.02694 0.4035 5.90278
76 3UDZ ADP 0.0000007555 0.5852 6.06061
77 1T36 ADP 0.009415 0.41275 6.06061
78 1CKM GTP 0.00994 0.41244 6.06061
79 1GSA ADP 0.02851 0.40987 6.06061
80 3VPC ADP 0.0003191 0.43454 6.38298
81 4CYI ATP 0.000004055 0.55521 6.39731
82 5IQD GNP 0.00008986 0.51961 6.39731
83 5IQD RIO 0.00009607 0.51961 6.39731
84 4OYA 1VE 0.009857 0.44172 6.39731
85 3B6R CRN 0.002908 0.40714 6.39731
86 4EIL NDP 0.01869 0.40013 6.39731
87 2BKK ADP 0.0003579 0.47109 6.43939
88 1TZD ADP 0.0005329 0.48261 6.54545
89 3TDV GDP 0.0000001355 0.59755 6.73401
90 4WCX MET 0.005111 0.42909 6.73401
91 5TDF ADP 0.003694 0.42164 6.73401
92 4RDL FUC GAL NDG FUC 0.01964 0.40429 6.73401
93 1W2D ADP 0.0002995 0.48056 6.79245
94 4LO2 GAL BGC 0.01154 0.41353 6.80272
95 2QX0 PH2 0.002627 0.4527 6.91824
96 5T96 79J 0.01066 0.41147 7.07071
97 2XG5 EC5 0.009098 0.41047 7.33945
98 2XG5 EC2 0.009098 0.41047 7.33945
99 5I35 ANP 0.00002354 0.51278 7.74411
100 4FFG LBS 0.006212 0.40908 7.74411
101 1PK8 ATP 0.0007997 0.40599 7.81991
102 4GYI ADP 0.00000504 0.55704 8.08081
103 1I7L ATP 0.0007491 0.45878 8.08081
104 4PU5 ANP 0.0005189 0.4241 8.08081
105 2NGR AF3 0.01469 0.40855 8.11966
106 2AQX ATP 0.001166 0.41485 8.3045
107 4CS9 AMP 0.007375 0.41152 8.46561
108 1JG3 ADN 0.01224 0.41009 8.51064
109 4IX4 ADP 0.00001692 0.52721 8.75421
110 4Z4P SAH 0.004724 0.41079 8.75421
111 2R3A SAM 0.00502 0.41172 9.09091
112 5L2J 6UL 0.03534 0.41381 9.18367
113 1TQP ATP 0.00000515 0.48609 9.21986
114 3ZJX BOG 0.002915 0.44681 9.34256
115 4OAV ACP 0.00000001219 0.65825 9.42761
116 2UYN 2KT 0.007602 0.42097 10.0775
117 2BVE PH5 0.03222 0.40508 10.084
118 2BOS GLA GAL 0.02202 0.40245 10.2941
119 1Y7P RIP 0.008012 0.40476 10.3139
120 4WW7 AMP 0.000004627 0.55522 10.3448
121 5W2I ADP 0.0003931 0.47163 11.284
122 5W2I I3P 0.0003931 0.47163 11.284
123 5K2M ADP 0.001174 0.44983 11.3208
124 1IA9 ANP 0.00002217 0.49577 11.7857
125 1W1A NDG 0.006336 0.43077 12.0623
126 3KA2 2NC 0.003291 0.45754 13.3005
127 5ML3 DL3 0.00792 0.42734 13.4228
128 1U72 NDP 0.03115 0.41014 13.4409
129 1U72 MTX 0.03115 0.41014 13.4409
130 4Q5H ANP 0.0000005688 0.57176 13.4615
131 4XYM A12 0.0005223 0.45784 13.4783
132 4TXJ THM 0.01888 0.40242 13.8514
133 2IO8 ADP 0.0002326 0.42718 14.1414
134 4AZT LY2 0.003238 0.43133 14.4781
135 3MTX PGT 0.0162 0.40679 14.5695
136 3LQV ADE 0.01353 0.40397 14.7826
137 1ZP9 ATP 0.000001723 0.57064 15.1163
138 1ZTH ADP 0.0000005155 0.55553 15.1163
139 3HAV ATP 0.002454 0.44996 15.1515
140 3VPB ADP 0.00009303 0.43695 16.0714
141 5CKW ANP 0.00001887 0.4967 16.4983
142 5C03 AGS 0.000005702 0.52884 19.5286
143 4WOV 3SM 0.00004855 0.51137 19.5286
144 4AZW ATP 0.0007623 0.4526 19.5286
145 3VHE 42Q 0.0000001838 0.48461 21.2121
146 4O1P ANP 0.00000000218 0.69533 22.2222
147 4XH0 ADP 0.0000006719 0.6335 23.569
148 2QLU ADE 0.00000003253 0.72956 26.5993
149 4KBA 1QM 0.00003987 0.43704 26.5993
150 5KO1 6UY 0.0000001405 0.61125 27.6094
151 3KMW ATP 0.0001014 0.4847 28.0443
152 5JFS 6K0 0.0000006587 0.62705 28.2828
153 3E8N VRA 0.000000001015 0.47073 28.2828
154 3E8N ATP 0.000000001015 0.47073 28.2828
155 4EWH T77 0.000000004156 0.55718 28.3636
156 4Y93 746 0.0000005811 0.50511 29.6296
157 2OFV 242 0.000006312 0.42337 29.9639
158 4AT3 LTI 0.0000009435 0.46682 29.9663
159 4YMJ 4EJ 0.000001346 0.6159 30.303
160 3UIM ANP 0.0000002365 0.5882 30.303
161 4E93 GUI 0.000000009346 0.5122 30.6397
162 1BYG STU 0.000000003005 0.69566 30.9353
163 4CRL C1I 0.000001079 0.45181 30.9764
164 2XVD AS6 0.0000004227 0.4881 31.3131
165 3SXS PP2 0.0000001658 0.56455 31.3433
166 5HES 032 0.0000004525 0.60103 31.6498
167 2CSN CKI 0.00007158 0.54525 31.6498
168 5LPZ ADP 0.000000007993 0.6487 31.9865
169 1VJY 460 0.000000002241 0.73122 32.3232
170 3PP0 03Q 0.00000006174 0.52902 32.3232
171 5LPB ADP 0.00000005073 0.59576 32.4324
172 5USZ SKE 0.0000002941 0.50669 32.526
173 4E1Z 0MX 0.000000001614 0.61799 32.646
174 4IDT T28 0.0000000005419 0.71812 32.6599
175 5EOB 5QQ 0.0000007445 0.64137 32.6599
176 3H9R TAK 0.0000007581 0.61368 32.6599
177 5MJA 7O3 0.000003834 0.53884 32.6599
178 5FBN 5WF 0.0000001702 0.64635 32.8413
179 2Y6O 1N1 0.00002357 0.52313 32.9897
180 5T8O 76Z 0.000000005372 0.62264 32.9966
181 2A19 ANP 0.00000009156 0.64786 33.0986
182 1U59 STU 0.00000001948 0.6335 33.101
183 5CEO 50D 0.0000003636 0.59629 33.3333
184 4GJ3 0XP 0.00000000858 0.52221 33.3333
185 4U0I 0LI 0.00001502 0.42085 33.3333
186 4FL3 ANP 0.000000000101 0.6771 33.67
187 2OO8 RAJ 0.00157 0.40343 33.67
188 5C4L 4XR 0.00001954 0.54319 34.0067
189 3KRL KRL 0.000001473 0.51891 34.0067
190 5C4L SIS 0.0001975 0.49588 34.0067
191 3LXK MI1 0.000000000993 0.73731 34.3434
192 3PLS ANP 0.000000006499 0.67035 34.6801
193 5HX8 66P 0.00000001138 0.55943 34.6801
194 3VRY B43 0.0000009061 0.49679 34.6801
195 4FF8 14S 0.0006016 0.43171 34.6801
196 1OPK P16 0.00001052 0.43021 34.6801
197 4K33 ACP 0.000000000001928 0.83605 35.0168
198 1JPA ANP 0.000001756 0.60444 35.0168
199 5JKG 6LF 0.000002432 0.59643 35.0168
200 4P5Z Q7M 0.000004762 0.41378 35.0168
201 5NKB 8ZT 0.000002039 0.41062 35.3535
202 5HCY 60D 0.00000001652 0.70991 36.0269
203 4YLL 4E3 0.000000004363 0.69573 36.0269
204 3LXN MI1 0.0000000001135 0.6927 36.0269
205 3RI1 3RH 0.000000009194 0.68967 36.3636
206 4BKJ STI 0.002744 0.43457 36.3636
207 2PVF ACP 0.00000000004012 0.76817 36.7003
208 4CLI 5P8 0.0000001293 0.66628 36.7003
209 3SRV S19 0.0000000008496 0.70947 36.8231
210 5TO8 7FM 0.00000345 0.5907 36.8794
211 4YZC STU 0.000000001585 0.74756 37.037
212 4CSV STI 0.0002385 0.43215 37.0909
213 4F4P 0SB 0.000000588 0.65129 37.3626
214 1U5R ATP 0.0000000001137 0.72679 37.3737
215 3F7Z 34O 0.0000001033 0.62065 37.7104
216 4NM5 ADP 0.00000004834 0.56224 37.7104
217 3ZRM ZRM 0.000006851 0.53946 37.7104
218 2JLD AG1 0.0000000302 0.4991 37.7104
219 5MY8 RXZ 0.0000001171 0.63596 38.0471
220 3C1X CKK 0.00009841 0.45064 38.0471
221 2HK5 1BM 0.0000004254 0.59938 38.1481
222 4BTK DTQ 0.0000119 0.52877 38.3838
223 5LI1 ANP 0.0000000000008382 0.86112 39.0572
224 2H8H H8H 0.00000004437 0.61666 39.0572
225 1Y57 MPZ 0.0000002079 0.54053 39.0572
226 5UR1 YY9 0.000001724 0.60986 39.3939
227 4ASE AV9 0.000004276 0.45746 39.7306
228 4AG8 AXI 0.000001092 0.43422 39.7306
229 3GQI ACP 0.00000000002486 0.75447 40.0673
230 3BU5 ATP 0.000000001169 0.70739 40.0673
231 5LXC 7AA 0.00000000106 0.69172 40.0673
232 3GNI ATP 0.000000008863 0.61757 40.0673
233 4XLI 1N1 0.000003593 0.54892 40.2985
234 4Y85 499 0.00000398 0.54695 40.404
235 4TWP AXI 0.0000003418 0.41023 40.5904
236 3ALN