Receptor
PDB id Resolution Class Description Source Keywords
5KF6 1.7 Å NON-ENZYME: OTHER STRUCTURE OF PROLINE UTILIZATION A FROM SINORHIZOBIUM MELILO COMPLEXED WITH L-TETRAHYDROFUROIC ACID AND NAD+ IN SPACE GR SINORHIZOBIUM MELILOTI (STRAIN SM11) FLAVOENZYME ROSSMANN FOLD ALDEHYDE DEHYDROGENASE PROLINE CATABOLISM SUBSTRATE CHANNELING BIFUNCTIONAL ENZYME OXIDOREDUCTASE
Ref.: STRUCTURES OF PROLINE UTILIZATION A (PUTA) REVEAL T AND FUNCTIONS OF THE ALDEHYDE DEHYDROGENASE SUPERFA DOMAIN OF UNKNOWN FUNCTION. J.BIOL.CHEM. V. 291 24065 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAD B:2002;
A:2002;
Valid;
Valid;
none;
none;
submit data
663.425 C21 H27 N7 O14 P2 c1cc(...
TFB B:2003;
A:2003;
Valid;
Valid;
none;
none;
submit data
116.115 C5 H8 O3 C1C[C...
FAD A:2001;
B:2001;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
MG A:2004;
B:2004;
Invalid;
Invalid;
none;
none;
submit data
24.305 Mg [Mg+2...
PGE A:2007;
B:2006;
B:2008;
A:2006;
A:2005;
B:2007;
B:2009;
B:2005;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
150.173 C6 H14 O4 C(COC...
PG4 B:2010;
Invalid;
none;
submit data
194.226 C8 H18 O5 C(COC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5KF6 1.7 Å NON-ENZYME: OTHER STRUCTURE OF PROLINE UTILIZATION A FROM SINORHIZOBIUM MELILO COMPLEXED WITH L-TETRAHYDROFUROIC ACID AND NAD+ IN SPACE GR SINORHIZOBIUM MELILOTI (STRAIN SM11) FLAVOENZYME ROSSMANN FOLD ALDEHYDE DEHYDROGENASE PROLINE CATABOLISM SUBSTRATE CHANNELING BIFUNCTIONAL ENZYME OXIDOREDUCTASE
Ref.: STRUCTURES OF PROLINE UTILIZATION A (PUTA) REVEAL T AND FUNCTIONS OF THE ALDEHYDE DEHYDROGENASE SUPERFA DOMAIN OF UNKNOWN FUNCTION. J.BIOL.CHEM. V. 291 24065 2016
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1579 families.
1 5KF6 - TFB C5 H8 O3 C1C[C@H](O....
2 5KF7 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1312 families.
1 5KF6 - TFB C5 H8 O3 C1C[C@H](O....
2 5KF7 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 6BSN - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
2 3HAZ - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
3 4Q73 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 4Q71 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
5 4Q72 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
6 5KF6 - TFB C5 H8 O3 C1C[C@H](O....
7 5KF7 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAD; Similar ligands found: 244
No: Ligand ECFP6 Tc MDL keys Tc
1 A3D 0.872727 0.986111
2 NHD 0.821429 0.972222
3 NAP 0.811966 0.986111
4 NFD 0.791304 0.946667
5 NXX 0.765766 0.972603
6 DND 0.765766 0.972603
7 AMP NAD 0.74359 0.972222
8 ZID 0.737705 0.986111
9 NAQ 0.729508 0.934211
10 NAE 0.721311 0.959459
11 NA0 0.712 0.972603
12 TAP 0.704 0.921053
13 NDE 0.689922 0.972603
14 NAJ 0.683333 0.972222
15 NDC 0.679389 0.934211
16 NDO 0.674603 0.958904
17 N01 0.656 0.972222
18 CNA 0.642276 0.972603
19 NBP 0.621212 0.922078
20 8ID 0.609756 0.922078
21 ADP MG 0.584906 0.957747
22 A2D 0.576923 0.958333
23 ADP 0.575472 0.931507
24 NGD 0.574803 0.922078
25 BA3 0.566038 0.958333
26 M33 0.564815 0.918919
27 ADP PO3 0.563636 0.957747
28 ATP MG 0.563636 0.957747
29 AP5 0.560748 0.958333
30 B4P 0.560748 0.958333
31 AT4 0.555556 0.894737
32 AN2 0.555556 0.918919
33 GAP 0.553571 0.932432
34 OOB 0.551724 0.972222
35 CA0 0.550459 0.932432
36 9JJ 0.546053 0.898734
37 ACP 0.545455 0.906667
38 HEJ 0.545455 0.931507
39 KG4 0.545455 0.932432
40 ATP 0.545455 0.931507
41 DQV 0.544 0.972222
42 ALF ADP 0.54386 0.883117
43 ADP ALF 0.54386 0.883117
44 DAL AMP 0.543103 0.945205
45 8LQ 0.543103 0.92
46 AQP 0.540541 0.931507
47 AR6 0.540541 0.931507
48 5FA 0.540541 0.931507
49 APR 0.540541 0.931507
50 VO4 ADP 0.53913 0.945205
51 ADP VO4 0.53913 0.945205
52 AGS 0.535714 0.883117
53 AD9 0.535714 0.906667
54 SAP 0.535714 0.883117
55 WAQ 0.533333 0.896104
56 ABM 0.53271 0.905405
57 45A 0.53271 0.905405
58 00A 0.529412 0.921053
59 DLL 0.529412 0.972222
60 ACQ 0.526316 0.906667
61 ANP 0.526316 0.906667
62 NJP 0.526316 0.959459
63 OAD 0.525 0.932432
64 ADX 0.522523 0.839506
65 8LE 0.521739 0.907895
66 5AL 0.521739 0.945205
67 A1R 0.521008 0.871795
68 9SN 0.520325 0.909091
69 AMP 0.518868 0.930556
70 A 0.518868 0.930556
71 50T 0.517857 0.893333
72 ATF 0.517241 0.894737
73 3OD 0.516393 0.932432
74 1ZZ 0.516393 0.851852
75 SON 0.513514 0.92
76 PRX 0.513274 0.881579
77 SRP 0.512821 0.92
78 8LH 0.512821 0.92
79 6YZ 0.512821 0.906667
80 ADP BMA 0.512397 0.932432
81 9X8 0.512397 0.883117
82 3UK 0.512397 0.958904
83 MYR AMP 0.512195 0.851852
84 NAJ PZO 0.510949 0.909091
85 NMN 0.509434 0.875
86 HQG 0.508475 0.918919
87 A3R 0.508333 0.871795
88 B5V 0.508197 0.945946
89 AMP DBH 0.507937 0.906667
90 A22 0.504202 0.945205
91 ATP A A A 0.504 0.971831
92 B5M 0.504 0.933333
93 FA5 0.504 0.945946
94 ATP A 0.504 0.971831
95 8QN 0.5 0.945205
96 NAX 0.496183 0.886076
97 TYR AMP 0.496063 0.933333
98 PR8 0.495935 0.8625
99 ADQ 0.495868 0.932432
100 PAJ 0.495868 0.873418
101 4AD 0.495868 0.933333
102 AMO 0.495868 0.92
103 APC MG 0.495652 0.931507
104 AP2 0.495495 0.894737
105 A12 0.495495 0.894737
106 AHZ 0.492308 0.851852
107 YAP 0.492063 0.933333
108 FYA 0.491935 0.918919
109 AHX 0.491803 0.884615
110 4UU 0.488372 0.933333
111 5SV 0.487603 0.8375
112 T99 0.487179 0.894737
113 TAT 0.487179 0.894737
114 APC 0.486957 0.894737
115 SRA 0.486239 0.881579
116 NAI 0.484848 0.921053
117 6V0 0.484848 0.909091
118 GTA 0.484615 0.898734
119 LAD 0.483871 0.873418
120 A A 0.483871 0.958333
121 AU1 0.482456 0.906667
122 F2R 0.481752 0.831325
123 TXE 0.481203 0.921053
124 AF3 ADP 3PG 0.481203 0.873418
125 OMR 0.481203 0.841463
126 LAQ 0.480916 0.851852
127 G3A 0.48062 0.909091
128 B5Y 0.480315 0.933333
129 TXA 0.48 0.92
130 BIS 0.48 0.871795
131 NB8 0.48 0.884615
132 ME8 0.48 0.851852
133 PTJ 0.48 0.884615
134 139 0.477941 0.886076
135 LPA AMP 0.477273 0.851852
136 ARG AMP 0.476923 0.841463
137 AR6 AR6 0.476923 0.958333
138 G5P 0.476923 0.909091
139 AFH 0.476923 0.873418
140 25L 0.47619 0.945205
141 NAJ PYZ 0.475524 0.864198
142 25A 0.47541 0.958333
143 9ZA 0.47541 0.896104
144 9ZD 0.47541 0.896104
145 OZV 0.47541 0.931507
146 DZD 0.47482 0.897436
147 TXD 0.473684 0.921053
148 4UV 0.472868 0.933333
149 TYM 0.470149 0.945946
150 ADV 0.470085 0.894737
151 RBY 0.470085 0.894737
152 4TA 0.467626 0.864198
153 48N 0.466165 0.884615
154 XAH 0.465116 0.851852
155 4UW 0.462687 0.897436
156 M24 0.461538 0.886076
157 80F 0.460993 0.853659
158 IOT 0.459854 0.821429
159 T5A 0.456522 0.853659
160 EAD 0.455782 0.886076
161 MAP 0.455285 0.883117
162 GA7 0.454545 0.894737
163 BT5 0.453901 0.821429
164 A4P 0.452555 0.833333
165 UP5 0.451852 0.933333
166 PAP 0.445378 0.917808
167 4TC 0.445255 0.909091
168 AP0 0.445255 0.884615
169 YLP 0.444444 0.831325
170 P1H 0.443709 0.864198
171 AOC 0.442478 0.810811
172 Z5A 0.439189 0.833333
173 LMS 0.4375 0.817073
174 2A5 0.436975 0.857143
175 A G 0.43662 0.921053
176 COD 0.43662 0.802326
177 G A A A 0.43662 0.909091
178 ADJ 0.435714 0.841463
179 YLB 0.434783 0.831325
180 YLC 0.434783 0.851852
181 U A G G 0.433566 0.921053
182 ATR 0.433333 0.90411
183 7MD 0.432836 0.851852
184 8X1 0.432 0.764045
185 G5A 0.429752 0.790698
186 PO4 PO4 A A A A PO4 0.429688 0.943662
187 TAD 0.42963 0.873418
188 5AS 0.42735 0.770115
189 BTX 0.426573 0.831325
190 YLA 0.425532 0.831325
191 DSZ 0.425197 0.790698
192 NCN 0.424779 0.805556
193 UPA 0.42446 0.921053
194 8PZ 0.424242 0.811765
195 VMS 0.424 0.8
196 54H 0.424 0.8
197 9K8 0.423077 0.744444
198 N0B 0.422819 0.853659
199 6AD 0.422764 0.85
200 AYB 0.422535 0.821429
201 7D3 0.422414 0.844156
202 YLY 0.421769 0.821429
203 TSB 0.420635 0.809524
204 ODP 0.41958 0.922078
205 AV2 0.419355 0.855263
206 A5A 0.419355 0.819277
207 FB0 0.419355 0.775281
208 NNR 0.419048 0.739726
209 A A A 0.418605 0.918919
210 U A 0.417808 0.946667
211 649 0.417266 0.775281
212 NMN AMP PO4 0.416667 0.933333
213 H1Q 0.416667 0.917808
214 SSA 0.416 0.790698
215 P5A 0.415385 0.755556
216 LSS 0.414062 0.772727
217 A2R 0.412698 0.918919
218 52H 0.412698 0.790698
219 JB6 0.412214 0.896104
220 5N5 0.411215 0.783784
221 YSA 0.410448 0.811765
222 B1U 0.410448 0.786517
223 53H 0.409449 0.790698
224 5CA 0.409449 0.790698
225 ITT 0.408333 0.878378
226 7D4 0.408333 0.844156
227 NA7 0.407692 0.894737
228 LEU LMS 0.407692 0.784091
229 5CD 0.407407 0.794521
230 0WD 0.406897 0.909091
231 A3P 0.40678 0.930556
232 JSQ 0.406504 0.883117
233 HFD 0.406504 0.883117
234 AVV 0.40625 0.860759
235 RAB 0.40566 0.808219
236 ADN 0.40566 0.808219
237 XYA 0.40566 0.808219
238 FDA 0.405063 0.823529
239 GSU 0.40458 0.790698
240 7MC 0.404255 0.831325
241 NSS 0.403101 0.811765
242 6FA 0.402516 0.853659
243 NVA LMS 0.4 0.784091
244 PPS 0.4 0.817073
Ligand no: 2; Ligand: TFB; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 TFB 1 1
Ligand no: 3; Ligand: FAD; Similar ligands found: 136
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 SAP 0.484615 0.811765
23 AGS 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 ATP 0.48062 0.851852
27 HEJ 0.48062 0.851852
28 AP5 0.480315 0.875
29 B4P 0.480315 0.875
30 ADP 0.480315 0.851852
31 ANP 0.477273 0.831325
32 5FA 0.476923 0.851852
33 AQP 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AT4 0.465116 0.821429
40 AN2 0.465116 0.841463
41 HQG 0.463235 0.841463
42 AD9 0.462121 0.831325
43 3OD 0.460993 0.876543
44 RBF 0.460938 0.790123
45 FB0 0.460606 0.835165
46 139 0.460526 0.858824
47 AP0 0.46 0.835294
48 A22 0.459854 0.864198
49 ACP 0.458015 0.853659
50 8QN 0.456522 0.864198
51 PRX 0.454545 0.831325
52 A1R 0.453237 0.86747
53 A3R 0.453237 0.86747
54 G3A 0.452055 0.902439
55 T5A 0.45098 0.872093
56 G5P 0.44898 0.902439
57 ATF 0.448529 0.821429
58 50T 0.44697 0.819277
59 OZV 0.446043 0.851852
60 6YZ 0.445255 0.853659
61 ACQ 0.444444 0.853659
62 CNV FAD 0.443182 0.917647
63 PAJ 0.442857 0.847059
64 ADQ 0.442857 0.853659
65 8LE 0.441176 0.855422
66 5AL 0.441176 0.864198
67 CA0 0.439394 0.853659
68 ADX 0.439394 0.775281
69 8LQ 0.438849 0.865854
70 A4P 0.437909 0.831461
71 25L 0.4375 0.864198
72 P33 FDA 0.436464 0.817204
73 KG4 0.43609 0.853659
74 5SV 0.435714 0.793103
75 8LH 0.434783 0.843373
76 OMR 0.434211 0.818182
77 TXE 0.434211 0.890244
78 45A 0.434109 0.829268
79 ABM 0.434109 0.829268
80 AMP 0.433071 0.82716
81 A 0.433071 0.82716
82 4AD 0.432624 0.855422
83 ADJ 0.432258 0.818182
84 B5Y 0.431507 0.878049
85 B5M 0.431507 0.878049
86 BIS 0.430556 0.802326
87 SRA 0.429688 0.788235
88 AFH 0.42953 0.825581
89 NXX 0.427632 0.865854
90 UP5 0.427632 0.878049
91 TXD 0.427632 0.890244
92 6V0 0.427632 0.857143
93 DND 0.427632 0.865854
94 DQV 0.426667 0.8875
95 SRP 0.42446 0.843373
96 PR8 0.423611 0.837209
97 TAT 0.423358 0.821429
98 T99 0.423358 0.821429
99 AMO 0.422535 0.865854
100 FYA 0.42069 0.864198
101 TXA 0.42069 0.865854
102 PTJ 0.42069 0.835294
103 CNA 0.420382 0.865854
104 00A 0.41958 0.823529
105 AHX 0.41958 0.835294
106 MAP 0.41844 0.811765
107 NAI 0.418301 0.845238
108 AU1 0.41791 0.831325
109 AP2 0.416667 0.843373
110 A12 0.416667 0.843373
111 9ZA 0.415493 0.845238
112 9ZD 0.415493 0.845238
113 25A 0.415493 0.851852
114 COD 0.415094 0.842697
115 4TC 0.412903 0.879518
116 APC 0.411765 0.843373
117 ME8 0.410959 0.806818
118 NB8 0.410959 0.835294
119 1ZZ 0.410959 0.806818
120 ADP MG 0.410448 0.82716
121 NAX 0.409091 0.837209
122 4UW 0.409091 0.825581
123 F2R 0.408805 0.850575
124 RBY 0.408759 0.843373
125 ADV 0.408759 0.843373
126 P1H 0.405882 0.818182
127 OOB 0.405594 0.864198
128 A A 0.40411 0.829268
129 LAD 0.40411 0.825581
130 UPA 0.403846 0.86747
131 4UU 0.401316 0.833333
132 GA7 0.401316 0.865854
133 A3D 0.401235 0.876543
134 80F 0.401235 0.808989
135 XAH 0.4 0.806818
136 DLL 0.4 0.864198
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5KF6; Ligand: NAD; Similar sites found with APoc: 72
This union binding pocket(no: 1) in the query (biounit: 5kf6.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 6MVU K4V 20.5997
2 6O4C NAD 33.9181
3 6O4C NAD 33.9181
4 6O4C NAD 33.9181
5 6O4C NAD 33.9181
6 6O4C NAD 33.9181
7 6O4C NAD 33.9181
8 6O4C NAD 33.9181
9 6O4C NAD 33.9181
10 4I8P NAD 37.8846
11 4I8P NAD 37.8846
12 4OE4 NAD 38.2759
13 4OE4 NAD 38.2759
14 4A0M NAD 38.3064
15 4A0M NAD 38.3064
16 4A0M NAD 38.3064
17 4A0M NAD 38.3064
18 6FK3 PPI 38.4328
19 6FK3 PPI 38.4328
20 2QE0 NAP 38.5263
21 2QE0 NAP 38.5263
22 2QE0 NAP 38.5263
23 2QE0 NAP 38.5263
24 4NS3 NAD 38.7211
25 4NS3 NAD 38.7211
26 4PXL NAD 39.0716
27 3RHJ NAP 39.4584
28 3RHJ NAP 39.4584
29 3RHJ NAP 39.4584
30 3RHJ NAP 39.4584
31 4LH0 GLV 39.6092
32 4LH0 GLV 39.6092
33 4I3V NAD 40.1639
34 4I3V NAD 40.1639
35 4I3V NAD 40.1639
36 4I3V NAD 40.1639
37 4I3V NAD 40.1639
38 4I3V NAD 40.1639
39 4I3V NAD 40.1639
40 5N5S NAP 40.5825
41 5N5S NAP 40.5825
42 5N5S NAP 40.5825
43 6RTT 6PC 41.0156
44 6RTT 6PC 41.0156
45 6RTT 6PC 41.0156
46 5L13 6ZE 41.5861
47 5L13 6ZE 41.5861
48 5L13 6ZE 41.5861
49 5L13 6ZE 41.5861
50 5L13 6ZE 41.5861
51 5L13 6ZE 41.5861
52 5L13 6ZE 41.5861
53 5L13 6ZE 41.5861
54 1O9J NAD 41.7166
55 1O9J NAD 41.7166
56 1O9J NAD 41.7166
57 1O9J NAD 41.7166
58 1KY8 NAP 42.515
59 1T90 NAD 43.0041
60 1T90 NAD 43.0041
61 1T90 NAD 43.0041
62 1T90 NAD 43.0041
63 2WOX NDP 43.3538
64 2WOX NDP 43.3538
65 2WOX NDP 43.3538
66 2WOX NDP 43.3538
67 2BJK NAD 45.5426
68 2BJK NAD 45.5426
69 5IUW IAC 45.674
70 5IUW IAC 45.674
71 5IUW NAD 45.674
72 5IUW NAD 45.674
Pocket No.: 2; Query (leader) PDB : 5KF6; Ligand: TFB; Similar sites found with APoc: 6
This union binding pocket(no: 2) in the query (biounit: 5kf6.bio1) has 34 residues
No: Leader PDB Ligand Sequence Similarity
1 4NMC 2OP 44.0796
2 4NMC FAD 44.0796
3 4NMC FAD 44.0796
4 4H6Q TFB 45.8333
5 4H6Q FAD 45.8333
6 4H6Q TFB 45.8333
Pocket No.: 3; Query (leader) PDB : 5KF6; Ligand: FAD; Similar sites found with APoc: 6
This union binding pocket(no: 3) in the query (biounit: 5kf6.bio1) has 34 residues
No: Leader PDB Ligand Sequence Similarity
1 4NMC 2OP 44.0796
2 4NMC FAD 44.0796
3 4NMC FAD 44.0796
4 4H6Q TFB 45.8333
5 4H6Q FAD 45.8333
6 4H6Q TFB 45.8333
Pocket No.: 4; Query (leader) PDB : 5KF6; Ligand: FAD; Similar sites found with APoc: 5
This union binding pocket(no: 4) in the query (biounit: 5kf6.bio2) has 30 residues
No: Leader PDB Ligand Sequence Similarity
1 4NMC 2OP 44.0796
2 4NMC FAD 44.0796
3 4NMC FAD 44.0796
4 4H6Q FAD 45.8333
5 5M42 FMN 46.9534
Pocket No.: 5; Query (leader) PDB : 5KF6; Ligand: TFB; Similar sites found with APoc: 6
This union binding pocket(no: 5) in the query (biounit: 5kf6.bio2) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 4NMC 2OP 44.0796
2 4NMC FAD 44.0796
3 4H6Q TFB 45.8333
4 4H6Q TFB 45.8333
5 4H6Q FAD 45.8333
6 4H6Q FAD 45.8333
Pocket No.: 6; Query (leader) PDB : 5KF6; Ligand: NAD; Similar sites found with APoc: 78
This union binding pocket(no: 6) in the query (biounit: 5kf6.bio2) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 6D97 NAD 26.5082
2 6D97 NAD 26.5082
3 6D97 NAD 26.5082
4 6D97 NAD 26.5082
5 6O4C NAD 33.9181
6 6O4C NAD 33.9181
7 6O4C NAD 33.9181
8 6O4C NAD 33.9181
9 6O4C NAD 33.9181
10 6O4C NAD 33.9181
11 6O4C NAD 33.9181
12 6O4C NAD 33.9181
13 3EFV NAD 36.7965
14 3EFV NAD 36.7965
15 4I8P NAD 37.8846
16 4I8P NAD 37.8846
17 4I9B NAD 38.1045
18 4I9B NAD 38.1045
19 4OE4 NAD 38.2759
20 4OE4 NAD 38.2759
21 4A0M NAD 38.3064
22 4A0M NAD 38.3064
23 4A0M NAD 38.3064
24 4A0M NAD 38.3064
25 6FK3 PPI 38.4328
26 6FK3 PPI 38.4328
27 4NS3 NAD 38.7211
28 4NS3 NAD 38.7211
29 3IWK NAD 38.7674
30 3IWK NAD 38.7674
31 3IWK NAD 38.7674
32 3IWK NAD 38.7674
33 4PXL NAD 39.0716
34 4PXL NAD 39.0716
35 3RHJ NAP 39.4584
36 3RHJ NAP 39.4584
37 3RHJ NAP 39.4584
38 3RHJ NAP 39.4584
39 4LH0 GLV 39.6092
40 4LH0 GLV 39.6092
41 4I3V NAD 40.1639
42 4I3V NAD 40.1639
43 4I3V NAD 40.1639
44 4I3V NAD 40.1639
45 4I3V NAD 40.1639
46 4I3V NAD 40.1639
47 4I3V NAD 40.1639
48 5N5S NAP 40.5825
49 5N5S NAP 40.5825
50 6RTT 6PC 41.0156
51 6RTT 6PC 41.0156
52 6RTT 6PC 41.0156
53 5L13 6ZE 41.5861
54 5L13 6ZE 41.5861
55 5L13 6ZE 41.5861
56 5L13 6ZE 41.5861
57 5L13 6ZE 41.5861
58 5L13 6ZE 41.5861
59 5L13 6ZE 41.5861
60 5L13 6ZE 41.5861
61 1O9J NAD 41.7166
62 1O9J NAD 41.7166
63 1O9J NAD 41.7166
64 1O9J NAD 41.7166
65 1T90 NAD 43.0041
66 1T90 NAD 43.0041
67 1T90 NAD 43.0041
68 1T90 NAD 43.0041
69 2WOX NDP 43.3538
70 2WOX NDP 43.3538
71 2WOX NDP 43.3538
72 2WOX NDP 43.3538
73 2BJK NAD 45.5426
74 2BJK NAD 45.5426
75 5IUW IAC 45.674
76 5IUW IAC 45.674
77 5IUW NAD 45.674
78 5IUW NAD 45.674
Pocket No.: 7; Query (leader) PDB : 5KF6; Ligand: FAD; Similar sites found with APoc: 9
This union binding pocket(no: 7) in the query (biounit: 5kf6.bio3) has 30 residues
No: Leader PDB Ligand Sequence Similarity
1 4NMC FAD 44.0796
2 4NMC 2OP 44.0796
3 4NMC FAD 44.0796
4 4H6Q FAD 45.8333
5 4H6Q FAD 45.8333
6 4H6Q TFB 45.8333
7 2G37 FAD 46.4832
8 2G37 FAD 46.4832
9 5M42 FMN 46.9534
Pocket No.: 8; Query (leader) PDB : 5KF6; Ligand: NAD; Similar sites found with APoc: 85
This union binding pocket(no: 8) in the query (biounit: 5kf6.bio3) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 6MVU K4V 20.5997
2 6D97 NAD 26.5082
3 6D97 NAD 26.5082
4 6D97 NAD 26.5082
5 6D97 NAD 26.5082
6 6D97 NAD 26.5082
7 6D97 NAD 26.5082
8 2Y5D NAP 27.3408
9 6O4C NAD 33.9181
10 6O4C NAD 33.9181
11 6O4C NAD 33.9181
12 6O4C NAD 33.9181
13 3EFV NAD 36.7965
14 3EFV NAD 36.7965
15 3EFV NAD 36.7965
16 3IWJ NAD 37.5746
17 3IWJ NAD 37.5746
18 4I8P NAD 37.8846
19 4I8P NAD 37.8846
20 4I9B NAD 38.1045
21 4I9B NAD 38.1045
22 4OE4 NAD 38.2759
23 4OE4 NAD 38.2759
24 4A0M NAD 38.3064
25 4A0M NAD 38.3064
26 4A0M NAD 38.3064
27 4A0M NAD 38.3064
28 4NS3 NAD 38.7211
29 4NS3 NAD 38.7211
30 3IWK NAD 38.7674
31 3IWK NAD 38.7674
32 3IWK NAD 38.7674
33 3IWK NAD 38.7674
34 3IWK NAD 38.7674
35 3IWK NAD 38.7674
36 3IWK NAD 38.7674
37 3IWK NAD 38.7674
38 3IWK NAD 38.7674
39 4PXL NAD 39.0716
40 4PXL NAD 39.0716
41 3RHJ NAP 39.4584
42 3RHJ NAP 39.4584
43 3RHJ NAP 39.4584
44 3RHJ NAP 39.4584
45 4LH0 GLV 39.6092
46 4LH0 GLV 39.6092
47 4I3V NAD 40.1639
48 4I3V NAD 40.1639
49 4I3V NAD 40.1639
50 4I3V NAD 40.1639
51 4I3V NAD 40.1639
52 4I3V NAD 40.1639
53 4I3V NAD 40.1639
54 5N5S NAP 40.5825
55 5N5S NAP 40.5825
56 5L13 6ZE 41.5861
57 5L13 6ZE 41.5861
58 5L13 6ZE 41.5861
59 5L13 6ZE 41.5861
60 1O9J NAD 41.7166
61 1O9J NAD 41.7166
62 1O9J NAD 41.7166
63 1O9J NAD 41.7166
64 1T90 NAD 43.0041
65 1T90 NAD 43.0041
66 1T90 NAD 43.0041
67 1T90 NAD 43.0041
68 3JZ4 NAP 43.0353
69 3JZ4 NAP 43.0353
70 3JZ4 NAP 43.0353
71 3JZ4 NAP 43.0353
72 2WME NAP 43.2653
73 2WME NAP 43.2653
74 2WME NAP 43.2653
75 2WME NAP 43.2653
76 2WOX NDP 43.3538
77 2WOX NDP 43.3538
78 2WOX NDP 43.3538
79 2WOX NDP 43.3538
80 2BJK NAD 45.5426
81 2BJK NAD 45.5426
82 5IUW IAC 45.674
83 5IUW IAC 45.674
84 5IUW NAD 45.674
85 5IUW NAD 45.674
Pocket No.: 9; Query (leader) PDB : 5KF6; Ligand: TFB; Similar sites found with APoc: 10
This union binding pocket(no: 9) in the query (biounit: 5kf6.bio3) has 34 residues
No: Leader PDB Ligand Sequence Similarity
1 4NMC 2OP 44.0796
2 4NMC FAD 44.0796
3 4NMC FAD 44.0796
4 4H6Q TFB 45.8333
5 4H6Q FAD 45.8333
6 4H6Q TFB 45.8333
7 4H6Q FAD 45.8333
8 2G37 FAD 46.4832
9 2G37 FAD 46.4832
10 5M42 FMN 46.9534
Pocket No.: 10; Query (leader) PDB : 5KF6; Ligand: FAD; Similar sites found with APoc: 10
This union binding pocket(no: 10) in the query (biounit: 5kf6.bio3) has 34 residues
No: Leader PDB Ligand Sequence Similarity
1 4NMC 2OP 44.0796
2 4NMC FAD 44.0796
3 4NMC FAD 44.0796
4 4H6Q TFB 45.8333
5 4H6Q FAD 45.8333
6 4H6Q TFB 45.8333
7 4H6Q FAD 45.8333
8 2G37 FAD 46.4832
9 2G37 FAD 46.4832
10 5M42 FMN 46.9534
Pocket No.: 11; Query (leader) PDB : 5KF6; Ligand: TFB; Similar sites found with APoc: 6
This union binding pocket(no: 11) in the query (biounit: 5kf6.bio3) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 4NMC 2OP 44.0796
2 4NMC FAD 44.0796
3 4H6Q TFB 45.8333
4 4H6Q TFB 45.8333
5 4H6Q FAD 45.8333
6 4H6Q FAD 45.8333
Pocket No.: 12; Query (leader) PDB : 5KF6; Ligand: NAD; Similar sites found with APoc: 81
This union binding pocket(no: 12) in the query (biounit: 5kf6.bio3) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 6D97 NAD 26.5082
2 6D97 NAD 26.5082
3 6D97 NAD 26.5082
4 6D97 NAD 26.5082
5 6D97 NAD 26.5082
6 6D97 NAD 26.5082
7 2Y5D NAP 27.3408
8 6O4C NAD 33.9181
9 6O4C NAD 33.9181
10 6O4C NAD 33.9181
11 6O4C NAD 33.9181
12 3EFV NAD 36.7965
13 3EFV NAD 36.7965
14 3EFV NAD 36.7965
15 3IWJ NAD 37.5746
16 3IWJ NAD 37.5746
17 4I8P NAD 37.8846
18 4I8P NAD 37.8846
19 4I9B NAD 38.1045
20 4I9B NAD 38.1045
21 4OE4 NAD 38.2759
22 4OE4 NAD 38.2759
23 4A0M NAD 38.3064
24 4A0M NAD 38.3064
25 4A0M NAD 38.3064
26 4A0M NAD 38.3064
27 4NS3 NAD 38.7211
28 4NS3 NAD 38.7211
29 3IWK NAD 38.7674
30 3IWK NAD 38.7674
31 3IWK NAD 38.7674
32 3IWK NAD 38.7674
33 3IWK NAD 38.7674
34 3IWK NAD 38.7674
35 3IWK NAD 38.7674
36 3IWK NAD 38.7674
37 3IWK NAD 38.7674
38 4PXL NAD 39.0716
39 4PXL NAD 39.0716
40 3RHJ NAP 39.4584
41 3RHJ NAP 39.4584
42 3RHJ NAP 39.4584
43 3RHJ NAP 39.4584
44 4LH0 GLV 39.6092
45 4LH0 GLV 39.6092
46 4I3V NAD 40.1639
47 4I3V NAD 40.1639
48 4I3V NAD 40.1639
49 4I3V NAD 40.1639
50 4I3V NAD 40.1639
51 4I3V NAD 40.1639
52 5L13 6ZE 41.5861
53 5L13 6ZE 41.5861
54 5L13 6ZE 41.5861
55 5L13 6ZE 41.5861
56 1O9J NAD 41.7166
57 1O9J NAD 41.7166
58 1O9J NAD 41.7166
59 1O9J NAD 41.7166
60 1T90 NAD 43.0041
61 1T90 NAD 43.0041
62 1T90 NAD 43.0041
63 1T90 NAD 43.0041
64 3JZ4 NAP 43.0353
65 3JZ4 NAP 43.0353
66 3JZ4 NAP 43.0353
67 3JZ4 NAP 43.0353
68 2WME NAP 43.2653
69 2WME NAP 43.2653
70 2WME NAP 43.2653
71 2WME NAP 43.2653
72 2WOX NDP 43.3538
73 2WOX NDP 43.3538
74 2WOX NDP 43.3538
75 2WOX NDP 43.3538
76 2BJK NAD 45.5426
77 2BJK NAD 45.5426
78 5IUW IAC 45.674
79 5IUW IAC 45.674
80 5IUW NAD 45.674
81 5IUW NAD 45.674
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