Receptor
PDB id Resolution Class Description Source Keywords
5KOR 2.2 Å EC: 2.4.1.69 ARABIDOPSIS THALIANA FUCOSYLTRANSFERASE 1 (FUT1) IN COMPLEX AND A XYLO-OLIGOSSACHARIDE ARABIDOPSIS THALIANA FUCOSYLTRANSFERASE COMPLEX XLLG TRANSFERASE
Ref.: STRUCTURE OF ARABIDOPSIS THALIANA FUT1 REVEALS A VA THE GT-B CLASS FOLD AND PROVIDES INSIGHT INTO XYLOG FUCOSYLATION. PLANT CELL V. 28 2352 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GAL XYS XYS BGC BGC BGC XYS GAL BGC B:607;
C:607;
Valid;
Valid;
none;
none;
submit data
1387.21 n/a O(C1O...
CL B:613;
C:617;
D:605;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
35.453 Cl [Cl-]
EDO A:604;
C:613;
B:611;
D:603;
D:602;
C:612;
A:603;
D:604;
C:616;
B:612;
A:602;
C:611;
C:614;
C:615;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
GDP D:601;
A:601;
B:601;
C:601;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5KOR 2.2 Å EC: 2.4.1.69 ARABIDOPSIS THALIANA FUCOSYLTRANSFERASE 1 (FUT1) IN COMPLEX AND A XYLO-OLIGOSSACHARIDE ARABIDOPSIS THALIANA FUCOSYLTRANSFERASE COMPLEX XLLG TRANSFERASE
Ref.: STRUCTURE OF ARABIDOPSIS THALIANA FUT1 REVEALS A VA THE GT-B CLASS FOLD AND PROVIDES INSIGHT INTO XYLOG FUCOSYLATION. PLANT CELL V. 28 2352 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5KOR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5KOR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5KOR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GAL XYS XYS BGC BGC BGC XYS GAL BGC; Similar ligands found: 114
No: Ligand ECFP6 Tc MDL keys Tc
1 BGC BGC XYS BGC GAL XYS BGC XYS GAL 1 1
2 GAL XYS XYS BGC BGC BGC XYS GAL BGC 1 1
3 GLC BGC BGC XYS BGC XYS XYS GAL GAL 1 1
4 GAL BGC BGC BGC XYS XYS 1 1
5 GLC BGC BGC XYS BGC XYS XYS GAL 1 1
6 GAL BGC BGC BGC XYS BGC XYS 0.949367 1
7 BGC BGC BGC XYS BGC XYS GAL 0.949367 1
8 BGC BGC BGC XYS GAL 0.860759 1
9 BGC BGC XYS BGC XYS GAL 0.855422 0.972222
10 BGC BGC XYS BGC BGC XYS XYS GAL GAL 0.855422 0.972222
11 BGC BGC BGC XYS BGC XYS XYS GAL GAL 0.855422 0.972222
12 BGC BGC BGC XYS BGC XYS XYS 0.848101 1
13 GLC BGC BGC XYS BGC XYS XYS 0.848101 1
14 BGC BGC XYS BGC XYS BGC XYS 0.848101 1
15 GLC GLC BGC XYS BGC XYS 0.835443 1
16 GLC BGC BGC BGC XYS BGC XYS XYS 0.819277 0.972222
17 BGC BGC BGC XYS BGC BGC 0.814815 1
18 XYS BGC BGC BGC BGC XYS BGC BGC BGC 0.814815 1
19 XYS BGC BGC XYS BGC XYS BGC BGC BGC 0.814815 1
20 BGC BGC XYS BGC 0.765432 1
21 GAL BGC BGC XYS 0.7625 1
22 GLC GLC XYS XYS 0.7 0.971429
23 NBG BGC BGC XYS BGC XYS XYS 0.621053 0.744681
24 BMA BMA GLA BMA BMA 0.593023 0.942857
25 GLC GLC GLC BGC 0.581395 0.942857
26 GLO BGC BGC XYS BGC XYS XYS 0.518868 0.972222
27 BMA BMA BMA 0.518519 0.942857
28 CE5 0.518519 0.942857
29 CE8 0.518519 0.942857
30 MTT 0.518519 0.942857
31 CTT 0.518519 0.942857
32 DXI 0.518519 0.942857
33 GLC BGC BGC BGC BGC BGC 0.518519 0.942857
34 GLA GAL GLC 0.518519 0.942857
35 GAL GAL GAL 0.518519 0.942857
36 CEX 0.518519 0.942857
37 B4G 0.518519 0.942857
38 BGC GLC GLC 0.518519 0.942857
39 BMA BMA BMA BMA BMA 0.518519 0.942857
40 BMA MAN BMA 0.518519 0.942857
41 GLC GLC GLC GLC GLC 0.518519 0.942857
42 BGC GLC GLC GLC 0.518519 0.942857
43 BGC BGC BGC GLC 0.518519 0.942857
44 BGC GLC GLC GLC GLC GLC GLC 0.518519 0.942857
45 CTR 0.518519 0.942857
46 MLR 0.518519 0.942857
47 GLC GLC GLC GLC GLC GLC GLC 0.518519 0.942857
48 GLC GLC BGC GLC GLC GLC GLC 0.518519 0.942857
49 BGC BGC BGC BGC BGC BGC 0.518519 0.942857
50 CT3 0.518519 0.942857
51 GLC GLC GLC GLC GLC GLC GLC GLC 0.518519 0.942857
52 GLC GAL GAL 0.518519 0.942857
53 MAN MAN BMA BMA BMA BMA 0.518519 0.942857
54 BGC GLC GLC GLC GLC 0.518519 0.942857
55 GLC BGC BGC BGC BGC 0.518519 0.942857
56 MT7 0.518519 0.942857
57 GLC BGC BGC 0.518519 0.942857
58 GLC BGC GLC 0.518519 0.942857
59 MAN BMA BMA 0.518519 0.942857
60 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.518519 0.942857
61 CE6 0.518519 0.942857
62 GLC GLC BGC 0.518519 0.942857
63 BMA BMA BMA BMA BMA BMA 0.518519 0.942857
64 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.518519 0.942857
65 MAN BMA BMA BMA BMA 0.518519 0.942857
66 CEY 0.518519 0.942857
67 LBT 0.506329 0.942857
68 CBI 0.506329 0.942857
69 GLA GLA 0.506329 0.942857
70 BGC GAL 0.506329 0.942857
71 BGC GLC 0.506329 0.942857
72 LAT 0.506329 0.942857
73 GLC GAL 0.506329 0.942857
74 BMA GAL 0.506329 0.942857
75 BGC BMA 0.506329 0.942857
76 CBK 0.506329 0.942857
77 GAL GLC 0.506329 0.942857
78 MAL MAL 0.506329 0.916667
79 MAB 0.506329 0.942857
80 GAL BGC 0.506329 0.942857
81 GLA GAL 0.506329 0.942857
82 B2G 0.506329 0.942857
83 BMA BMA 0.506329 0.942857
84 GLC BGC 0.506329 0.942857
85 N9S 0.506329 0.942857
86 MAL 0.506329 0.942857
87 GLC GLC GLC GLC GLC GLC 0.505618 0.942857
88 BMA BMA BMA BMA BMA BMA MAN 0.494118 0.916667
89 MAN BMA BMA BMA BMA BMA 0.494118 0.916667
90 BMA BMA BMA BMA GLA BMA GLA 0.481481 0.85
91 BMA MAN 0.46988 0.916667
92 BGC BGC BGC BGC 0.466667 0.942857
93 BGC BGC BGC BGC BGC BGC BGC BGC 0.466667 0.942857
94 GLA GAL GAL 0.454545 0.942857
95 GLA GAL BGC 0.454545 0.942857
96 ABD 0.436893 0.717391
97 GLC GLC GLC GLC 0.434783 0.942857
98 BGC BGC GLC 0.426966 0.942857
99 GLC GLC XYP 0.410526 0.942857
100 GLC GAL FUC 0.410526 0.916667
101 FUC LAT 0.410526 0.916667
102 BGC GAL FUC 0.410526 0.916667
103 FUC GAL GLC 0.410526 0.916667
104 LAT FUC 0.410526 0.916667
105 GLC GLC FRU 0.41 0.871795
106 MAN MAN MAN BMA MAN 0.405941 0.942857
107 GLC GLC G6D ACI GLC GLC GLC 0.405405 0.75
108 LAT GLA 0.404762 0.942857
109 G2F BGC BGC BGC BGC BGC 0.404255 0.825
110 GLC GLC ACI G6D GLC GLC 0.403509 0.702128
111 GLC GLC AGL HMC GLC 0.403509 0.702128
112 ACR GLC GLC GLC 0.403509 0.702128
113 GLC GLC DAF BGC 0.403509 0.702128
114 GLC GLC GLC G6D ADH GLC 0.4 0.693878
Ligand no: 2; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5KOR; Ligand: GDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5kor.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5KOR; Ligand: GDP; Similar sites found: 80
This union binding pocket(no: 2) in the query (biounit: 5kor.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4MRP GSH 0.01805 0.4241 1.34357
2 5N9X THR 0.01179 0.4195 1.34357
3 5M8T 0TR 0.01649 0.41158 1.34529
4 5GWE GWM 0.01878 0.40436 1.48148
5 4OKD GLC GLC GLC 0.02977 0.40382 1.53551
6 3SQP 3J8 0.02373 0.40946 1.67364
7 4V3I ASP LEU THR ARG PRO 0.01083 0.42907 1.94553
8 5IJJ I6P 0.01833 0.41281 2.08333
9 5AWV GHP 3MY 3FG GHP GHP OMY 3FG NAG MAN 0.013 0.43884 2.11132
10 3B6C SDN 0.02303 0.4041 2.13675
11 3P9T TCL 0.01708 0.40236 2.28311
12 5DXE EST 0.01204 0.40199 2.29885
13 3HYW DCQ 0.01641 0.41447 2.30326
14 4TV1 36M 0.01177 0.4191 2.39044
15 5HVJ ANP 0.02445 0.40374 2.53968
16 1C3X 8IG 0.01543 0.41435 2.63158
17 4RW3 TDA 0.00278 0.47368 2.64901
18 4RW3 PLM 0.02253 0.42652 2.64901
19 4URN NOV 0.02202 0.4051 2.66667
20 1JJ7 ADP 0.02838 0.40709 2.69231
21 4IYO NAK 0.01378 0.4198 2.77078
22 4NV0 MG7 0.01405 0.40257 2.82132
23 3TDC 0EU 0.01025 0.46683 2.87908
24 4ORM 2V6 0.02572 0.41221 2.99252
25 4ORM FMN 0.02572 0.41221 2.99252
26 4ORM ORO 0.02572 0.41221 2.99252
27 4QVX 3CQ 0.004151 0.40225 2.99401
28 2WG9 OCA 0.02283 0.40429 3.07692
29 5V4R MGT 0.002385 0.46176 3.08642
30 2HHP FLC 0.0001297 0.54226 3.45489
31 2PZE ATP 0.0261 0.40714 3.49345
32 5UXH GFB 0.0000007804 0.56593 3.54223
33 4IEH 1E9 0.006693 0.4047 3.5503
34 2HAW 2PN 0.02285 0.40452 3.55987
35 5KXQ GDP 0.00000007867 0.65097 3.67232
36 1M2Z BOG 0.03711 0.41053 3.89105
37 3AQT RCO 0.004189 0.44907 4.08163
38 2W3L DRO 0.01718 0.41251 4.16667
39 4UCC ZKW 0.002982 0.46183 4.29185
40 1TV5 N8E 0.003043 0.4607 4.74041
41 5X30 HCS 0.007542 0.42846 4.77387
42 4ZGM 32M 0.02471 0.41315 4.91803
43 2JHP GUN 0.02338 0.40405 4.9904
44 3FAL REA 0.01106 0.41156 5.3719
45 4BHL ARG 0.005916 0.43768 5.61798
46 4BG4 ARG 0.0176 0.41335 5.61798
47 4HBM 0Y7 0.01034 0.40505 5.83333
48 1RV1 IMZ 0.01539 0.40069 5.88235
49 2VWA PTY 0.02433 0.40795 5.94059
50 3ZY6 GFB 0.005745 0.43231 6.07735
51 4TR1 GSH 0.01578 0.41561 6.52174
52 3SIX GDP 0.0000004274 0.61622 6.66667
53 5FOE GDP 0.001749 0.41831 6.71785
54 2FT0 ACO 0.004517 0.4177 6.80851
55 5UGW GSH 0.01084 0.43848 6.85714
56 4O4Z N2O 0.001827 0.46555 7.14286
57 2AWN ADP 0.009664 0.43286 7.61155
58 4PPF FLC 0.02311 0.41108 7.71429
59 2JFZ DGL 0.03089 0.40586 7.84314
60 4OHB 5HM 0.01663 0.40292 9.47368
61 3HY9 098 0.007509 0.4007 9.50226
62 1Z82 G3P 0.01324 0.41648 9.55224
63 1Z82 G3H 0.01793 0.4097 9.55224
64 5UC9 MYR 0.02307 0.40634 10.177
65 3N7S 3N7 0.01382 0.42406 10.4167
66 2VOH CIT 0.006932 0.41307 11.465
67 4RF7 ARG 0.004239 0.45016 11.9002
68 5OCA 9QZ 0.006963 0.45389 11.9816
69 5U98 1KX 0.01705 0.41766 12.1212
70 5KY9 GDP 0.0000001947 0.62329 12.5
71 5KY3 GFB 0.00000602 0.53579 12.5
72 2Q4G CIT 0.007522 0.42907 13.1783
73 5KY5 GDP 0.00000009167 0.64783 15
74 4YSX E23 0.002427 0.45418 15.3846
75 4JMU 1ML 0.01128 0.42005 16.0714
76 1GEG GLC 0.02527 0.41029 16.4062
77 1XVB 3BR 0.01531 0.40468 16.4706
78 5KY4 GDP 0.0000001407 0.64882 17.5
79 1SR7 MOF 0.009405 0.40803 18.5328
80 2Y69 CHD 0.02492 0.40121 20
Pocket No.: 3; Query (leader) PDB : 5KOR; Ligand: GAL XYS XYS BGC BGC BGC XYS GAL BGC; Similar sites found: 1
This union binding pocket(no: 3) in the query (biounit: 5kor.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4OWK NGA 0.01239 0.40612 4.34783
Pocket No.: 4; Query (leader) PDB : 5KOR; Ligand: GDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5kor.bio2) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 5KOR; Ligand: GDP; Similar sites found: 12
This union binding pocket(no: 5) in the query (biounit: 5kor.bio2) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4MGA 27L 0.0124 0.41671 2.35294
2 3UUD EST 0.01192 0.40218 2.39044
3 1G6H ADP 0.0184 0.4185 2.72374
4 3CYQ AMU 0.004164 0.45111 2.89855
5 4XH0 ADP 0.01126 0.42127 3.47395
6 2W58 ADP 0.03652 0.40054 3.9604
7 4K7O EKZ 0.02741 0.40393 4.16667
8 3IT6 ORN 0.01874 0.41048 4.87805
9 1L0I PSR 0.03156 0.40308 5.12821
10 1D8C GLV 0.02599 0.40008 5.37428
11 2OFE NAG 0.03249 0.40078 8.4507
12 2CBZ ATP 0.0127 0.42393 13.5021
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