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Receptor
PDB id Resolution Class Description Source Keywords
5KOX 1.8 Å EC: 1.14.13.50 STRUCTURE OF RIFAMPICIN MONOOXYGENASE COMPLEXED WITH RIFAMPI NOCARDIA FARCINICA FLAVOPROTEIN MONOOXYGENASE OXIDOREDUCTASE
Ref.: THE STRUCTURE OF THE ANTIBIOTIC DEACTIVATING, N-HYDROXYLATING RIFAMPICIN MONOOXYGENASE. J.BIOL.CHEM. V. 291 21553 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
RFP A:502;
Valid;
Atoms found LESS than expected: % Diff = 0;
Kd = 13 uM
822.94 C43 H58 N4 O12 Cc1c(...
FAD A:501;
Valid;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5KOX 1.8 Å EC: 1.14.13.50 STRUCTURE OF RIFAMPICIN MONOOXYGENASE COMPLEXED WITH RIFAMPI NOCARDIA FARCINICA FLAVOPROTEIN MONOOXYGENASE OXIDOREDUCTASE
Ref.: THE STRUCTURE OF THE ANTIBIOTIC DEACTIVATING, N-HYDROXYLATING RIFAMPICIN MONOOXYGENASE. J.BIOL.CHEM. V. 291 21553 2016
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 6C7S - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 5KOW - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 5KOX Kd = 13 uM RFP C43 H58 N4 O12 Cc1c(c2c3c....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 6C7S - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 5KOW - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 5KOX Kd = 13 uM RFP C43 H58 N4 O12 Cc1c(c2c3c....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 6C7S - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 5KOW - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 5KOX Kd = 13 uM RFP C43 H58 N4 O12 Cc1c(c2c3c....
4 4ICY - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
5 2QA1 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
6 4K5S - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
7 4K5R - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: RFP; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 RFP 1 1
2 RPT 0.858156 0.961039
3 RBT 0.511628 0.793103
Ligand no: 2; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5KOX; Ligand: RFP; Similar sites found with APoc: 954
This union binding pocket(no: 1) in the query (biounit: 5kox.bio1) has 58 residues
No: Leader PDB Ligand Sequence Similarity
1 3U31 NAD 1.03448
2 1CDO NAD 1.06952
3 5Z75 NAD 1.22324
4 2PT9 S4M 1.24611
5 2PT9 2MH 1.24611
6 5OC1 FAD 1.2605
7 1Z45 NAD 1.2605
8 1PJS NAD 1.31291
9 1YQZ FAD 1.36986
10 2Z49 AMG 1.38889
11 2I7C AAT 1.41343
12 5A2Z GTP 1.47059
13 3ULK NDP 1.47059
14 1U1I NAD 1.53061
15 5K4W NAI 1.55763
16 5K4W THR 1.55763
17 5ERG SAM 1.56658
18 2D2I NAP 1.57895
19 3G5S FAD 1.58014
20 1E3I CXF 1.59574
21 1GUZ NAD 1.6129
22 1FP1 SAH 1.6129
23 1CX4 CMP 1.63934
24 2JJQ SAH 1.64706
25 5JE8 NAD 1.65563
26 1DJN ADP 1.68067
27 5DXA SFG 1.7192
28 5DX8 SFG 1.7192
29 5DWQ SFG 1.7192
30 5DX1 SFG 1.7192
31 5DX0 SFG 1.7192
32 5THY SAH 1.7284
33 5THZ SAH 1.7284
34 4OOE NDP 1.73267
35 2B4R AES 1.73913
36 2B4R NAD 1.73913
37 4M37 SAH 1.74927
38 5KOK SAH 1.76322
39 3B20 NAD 1.76991
40 3B1J NAD 1.76991
41 4MP8 MLI 1.76991
42 4MP8 NAD 1.76991
43 4KVL PLM 1.77134
44 2HK9 ATR 1.81818
45 2HK9 NAP 1.81818
46 5KVS NAP 1.81818
47 4HXY NDP 1.82648
48 3OJO NAD 1.85615
49 4R5M NAP 1.8617
50 4R5M 4NO 1.8617
51 2FK8 SAM 1.88679
52 1PS9 FAD 1.89076
53 1PS9 NAP 1.89076
54 6D6Y SAH 1.89076
55 1GZ4 ATP 1.89076
56 5JJR SAH 1.89076
57 2GZ3 NAP 1.91257
58 1KYZ SAH 1.91781
59 1FLJ GSH 1.92308
60 4JK3 NAD 1.9305
61 4J4H 1J1 1.9305
62 4J4H NAI 1.9305
63 4R6W SAH 1.93798
64 4OBW SAM 1.94553
65 3CIF NAD 1.94986
66 3CIF G3H 1.94986
67 1EBF NAD 1.95531
68 3DAG FEG 1.95531
69 2X6T NAP 1.96078
70 2O07 MTA 1.97368
71 2O07 SPD 1.97368
72 1O6Z NAD 1.9802
73 6GKV SAH 1.9943
74 5N6C NAD 2
75 1E5Q NDP 2
76 2YYY NAP 2.04082
77 1LC3 NAD 2.04082
78 2AOT SAH 2.05479
79 1JQD SAH 2.05479
80 1VJT NAD 2.07039
81 1CF2 NAP 2.07715
82 3KLJ FAD 2.07792
83 5AHO TLA 2.08333
84 4ZCC FAD 2.08333
85 4ZCC NAI 2.08333
86 4PLG OXM 2.09581
87 4PLG NAI 2.09581
88 3ICT ADP 2.10084
89 3ICS ADP 2.10084
90 3ICS FAD 2.10084
91 3ICR FAD 2.10084
92 3PT9 SAH 2.10084
93 2HQM FAD 2.10084
94 3ICT FAD 2.10084
95 4B63 ORN 2.10084
96 4B63 FAD 2.10084
97 4B63 NAP 2.10084
98 4LHD GLY 2.10084
99 5E4R NAP 2.10084
100 2BHZ MAL 2.10084
101 1W96 S1A 2.10084
102 4XQC NAD 2.10526
103 4XQC 13D 2.10526
104 4E13 NAD 2.12014
105 1GAD NAD 2.12121
106 4YT4 FE9 2.13333
107 2EG5 SAH 2.15054
108 1UP7 NAD 2.15827
109 4UCI SAM 2.16867
110 4M6T SAM 2.18579
111 3ABI NAD 2.19178
112 3K5I AIR 2.23325
113 2YY7 NAD 2.24359
114 1BXK NAD 2.25352
115 3VPH NAD 2.25806
116 3VPH OXM 2.25806
117 1EQ2 NAP 2.25806
118 2BO4 FLC 2.267
119 1GY8 NAD 2.267
120 4XUC SAM 2.29358
121 4XUC 43G 2.29358
122 2WET FAD 2.31092
123 6F97 FAD 2.31092
124 1GTE FAD 2.31092
125 4JJF FE9 2.32558
126 4FN4 NAD 2.3622
127 5G3U FDA 2.36407
128 5G3U ITW 2.36407
129 2XVF FAD 2.37069
130 2XVE FAD 2.37069
131 5Y8L HUI 2.37288
132 5Y8L NAD 2.37288
133 3V1Y NAD 2.37389
134 1RM4 NDP 2.37389
135 5FUB SAH 2.37389
136 2EJU SAH 2.38095
137 2VHW NAI 2.38727
138 6FDF SAH 2.39521
139 1XDS SAM 2.40642
140 1QZZ SAM 2.40642
141 1VQW FAD 2.407
142 9LDT NAD 2.40964
143 9LDB NAD 2.40964
144 4PLT NAI 2.41692
145 4PLT OXM 2.41692
146 1WP4 NDP 2.42215
147 4YAG NAI 2.42215
148 3GEG NAD 2.42915
149 1B8U NAD 2.43161
150 2HJR APR 2.43902
151 5ZBC FAD 2.43902
152 6C4T NA7 2.44444
153 2CDC NAP 2.45902
154 2CDC XYP 2.45902
155 2GVC FAD 2.46085
156 2NPX FAD 2.46085
157 2GV8 NDP 2.46085
158 2NPX NAD 2.46085
159 2GV8 FAD 2.46085
160 5L53 NAP 2.46914
161 2IXB NAD 2.47748
162 3LKZ SFG 2.49221
163 1EZ4 NAD 2.51572
164 5KVA SAM 2.51799
165 3X0V FAD 2.52101
166 4HA6 FAD 2.52101
167 1O0S NAI 2.52101
168 1GQ2 NAP 2.52101
169 6CC0 EWM 2.53165
170 2BQP GLC 2.5641
171 3A27 SAM 2.57353
172 4D3F NAP 2.58065
173 3FUU ADN 2.58303
174 1R37 NAD 2.59366
175 3V1U NAD 2.5974
176 4ITU NAI 2.60223
177 3T7S SAM 2.61194
178 3WBF NAP 2.62295
179 3WBF API 2.62295
180 4EUE NAI 2.63158
181 5GSN FAD 2.64901
182 5GSN NAP 2.64901
183 5GSN MMZ 2.64901
184 3A06 NDP 2.65957
185 1F6D UDP 2.65957
186 3L4S NAD 2.67857
187 3L4S 3PG 2.67857
188 2QES ADE 2.68199
189 2PV7 NAD 2.68456
190 1RPN NDP 2.68657
191 2ZIF SAM 2.6936
192 5XNC MTA 2.69542
193 1J49 NAD 2.7027
194 2AF6 FAD 2.71318
195 4NBW NAD 2.72374
196 4E5N NAD 2.72727
197 5JWC FAD 2.73109
198 3NKS FAD 2.73109
199 1X87 NAD 2.73109
200 5WP5 SAH 2.73109
201 5WP4 SAH 2.73109
202 5HSA FAS 2.73109
203 4PIV NDP 2.73109
204 5DN9 NAD 2.74725
205 1XTP SAI 2.75591
206 3B1F NAD 2.75862
207 5ZYN FAD 2.76008
208 5GUD NDP 2.76008
209 1J5P NAD 2.7668
210 5WUW NAP 2.78746
211 1SQF SAM 2.7972
212 4ONQ SFG 2.80112
213 2A92 NAI 2.80374
214 1E7S NAP 2.80374
215 5YRI GLC GLC 2.8169
216 4CJX NAP 2.82132
217 6F3M NAD 2.82609
218 4D06 NAR 2.82686
219 1I9G SAM 2.85714
220 5GWT NAD 2.8777
221 6A63 LAT 2.89855
222 5ZI2 NAD 2.89855
223 5ZI2 ADP 2.89855
224 3GDH SAH 2.90456
225 4XDZ NDP 2.91545
226 3VYW SAM 2.92208
227 4RQU NAD 2.93333
228 5NA1 FAD 2.94118
229 2ZXI FAD 2.94118
230 4MIG G3F 2.94118
231 3SQP FAD 2.94118
232 1FEC FAD 2.94118
233 3UCL NAP 2.94118
234 3UCL FAD 2.94118
235 3UCL CYH 2.94118
236 3TLJ SAH 2.94906
237 5KMS FAD 2.96296
238 5KMS NAD 2.96296
239 4L8V NAP 2.96736
240 1MV8 NAD 2.98165
241 1MUU NAD 2.98165
242 1N2X SAM 2.99003
243 2VYN NAD 2.99401
244 2GDZ NAD 2.99625
245 1J0X NAD 3.01205
246 3LU1 NAD 3.02198
247 4YAC NAI 3.0303
248 4D7E FAD 3.0303
249 1ZEM NAD 3.05344
250 1QCI ADE 3.05344
251 1ZBQ NAD 3.0581
252 3LE7 ADE 3.06513
253 3FPZ AHZ 3.06748
254 5LD5 NAD 3.07263
255 2AGC DAO 3.08642
256 5UAV NDP 3.10559
257 5UAV TFB 3.10559
258 1FK8 NAD 3.11284
259 1F06 NDP 3.125
260 1GEG NAD 3.125
261 1O94 ADP 3.125
262 1GZ6 NAI 3.1348
263 6EL3 NAP 3.14961
264 3CGB FAD 3.15126
265 5TS5 FAD 3.15126
266 6F7L FAD 3.15126
267 2IID PHE 3.15126
268 2IID FAD 3.15126
269 3CGD NAD 3.15126
270 6H3O FAD 3.15126
271 1COY FAD 3.15126
272 1OBB NAD 3.15126
273 4MOP 2H5 3.15126
274 3CGD COA 3.15126
275 3CGD FAD 3.15126
276 6A3J NAI 3.17073
277 2E5V FAD 3.17797
278 5KKA 6V0 3.20513
279 3WV8 ATP 3.21101
280 5A96 GTP 3.21285
281 3JWH SAH 3.22581
282 1XG5 NAP 3.22581
283 1F8F NAD 3.2345
284 1HYH NAD 3.23625
285 2BGM NAJ 3.23741
286 1E1M NAP 3.26087
287 1E1M FAD 3.26087
288 4XMF HSM 3.26087
289 4N49 SAM 3.27103
290 1IM8 SAI 3.27869
291 4XB2 NDP 3.28358
292 4XB2 HSE 3.28358
293 6F9Q NAD 3.30882
294 2DT5 NAD 3.31754
295 1NYT NAP 3.32103
296 1QO8 FAD 3.36134
297 5UAO FAD 3.36134
298 3X0D SAH 3.36134
299 3S1S SAH 3.36134
300 2DC1 NAD 3.38983
301 3EGI ADP 3.39806
302 3H5N ATP 3.39943
303 1VL0 NAI 3.42466
304 6ECT SAM 3.42679
305 4J1Q NDP 3.44828
306 1U7T NAD 3.44828
307 3LST SAH 3.44828
308 3S5W FAD 3.45572
309 3S5W NAP 3.45572
310 3ZNN 4WL 3.45821
311 3ZNN FAD 3.45821
312 2CVZ NDP 3.46021
313 1KPG SAH 3.48432
314 1KPH SAH 3.48432
315 6DNT NAD 3.48837
316 3GGO ENO 3.50318
317 3GGO NAI 3.50318
318 1LLU NAD 3.50877
319 5YSS NAD 3.51562
320 5E5U MLI 3.51759
321 5N5D SAM 3.53982
322 5BJX UDP 3.55191
323 5BJX NAD 3.55191
324 1N1G BCP 3.55191
325 5ZW3 SAH 3.55556
326 1V59 NAD 3.57143
327 5EB4 FAD 3.57143
328 2UYQ SAM 3.57143
329 1V59 FAD 3.57143
330 4AT0 FAD 3.57143
331 5MBX SP5 3.57143
332 5MBX FAD 3.57143
333 2Z3Y F2N 3.57143
334 2V6G NAP 3.57143
335 5EJ2 NAD 3.57143
336 4BVA NDP 3.58209
337 4JDR FAD 3.5865
338 6C4M NAP 3.5865
339 3KB6 NAD 3.59281
340 4RSL FAD 3.59551
341 1K3T BRZ 3.62117
342 1PZG A3D 3.62538
343 3A4T SFG 3.64964
344 1PL6 NAD 3.65169
345 1PL6 572 3.65169
346 5TTJ FAD 3.67347
347 5THQ NDP 3.67647
348 4GN8 ASO 3.67893
349 6GNO XDI 3.7037
350 4CS9 AMP 3.7037
351 5F8F SFG 3.71353
352 4DCM SAM 3.73333
353 3RFV 15L 3.74532
354 3RFV NAI 3.74532
355 1IY8 NAD 3.74532
356 1ORR NAD 3.7464
357 2YG3 FAD 3.75276
358 1P0F NAP 3.75335
359 5NMX FAD 3.76471
360 5NMX NAP 3.76471
361 4KFU ACP 3.77358
362 1RSG FAD 3.78151
363 1YY5 FAD 3.78151
364 1BZL FAD 3.78151
365 5J7X FAD 3.78151
366 1NAA 6FA 3.78151
367 4Z24 FAD 3.78151
368 1NAA ABL 3.78151
369 5YB7 FAD 3.78151
370 5YB7 ORN 3.78151
371 4IV9 FAD 3.78151
372 1BZL GCG 3.78151
373 3UOY NAP 3.78151
374 3UOY FAD 3.78151
375 2Q28 ADP 3.78151
376 1G55 SAH 3.79009
377 5TC4 NAD 3.79747
378 2AG8 NAP 3.80228
379 4OSP NAP 3.80228
380 3ZJX BOG 3.80623
381 4REP FAD 3.83838
382 5ZZ6 ADP 3.84615
383 5ZZ6 NAD 3.84615
384 1WDK NAD 3.84615
385 5AOA PPI 3.84615
386 1ZK7 FAD 3.85439
387 3QV1 NAD 3.85757
388 1ZQ9 SAM 3.85965
389 1WG8 SAM 3.85965
390 1B1C FMN 3.8674
391 5AOV NAP 3.86905
392 2GTF P1R 3.88889
393 4Z0H NAD 3.89222
394 2G5C NAD 3.91459
395 3MB5 SAM 3.92157
396 1RYI FAD 3.9267
397 1RYI GOA 3.9267
398 5X9D 80F 3.94737
399 1YXM ADE 3.9604
400 5HJM MTA 3.97727
401 2IVD FAD 3.9916
402 1Y8Q ATP 3.9916
403 2VVL FAD 3.9916
404 3QVP FAD 3.9916
405 3Q9T FAY 3.9916
406 2WPF WPF 3.9916
407 2WPF FAD 3.9916
408 1UWK URO 3.9916
409 1UWK NAD 3.9916
410 2VVM FAD 3.9916
411 1DLJ NAI 3.9916
412 4POO SAM 4
413 6C4N NAP 4.00891
414 5ODQ FAD 4.01691
415 4URF NAD 4.03226
416 1OMO NAD 4.03727
417 1P77 ATR 4.04412
418 3GC8 B45 4.05405
419 4LWP SAH 4.07609
420 5X68 FAD 4.09207
421 2A8X FAD 4.09483
422 1HDR NAD 4.09836
423 1EDO NAP 4.09836
424 3H8V ATP 4.10959
425 5A04 BGC 4.12979
426 5A04 NDP 4.12979
427 1C0I FAD 4.13223
428 1C0I BE2 4.13223
429 4ZGS NAD 4.14508
430 4NTC FAD 4.1791
431 6CEP NAD 4.19162
432 6CEP OXM 4.19162
433 5WGR FAD 4.20168
434 1KNR FAD 4.20168
435 4C3Y FAD 4.20168
436 5MQ6 NDP 4.20168
437 4C3Y ANB 4.20168
438 2AQJ TRP 4.20168
439 2AQJ FAD 4.20168
440 5NM7 GLY 4.20168
441 4ISS TAR 4.20168
442 4DSG UDP 4.20168
443 4DSG FAD 4.20168
444 2FR1 NDP 4.20168
445 1MO9 FAD 4.20168
446 1MO9 KPC 4.20168
447 1CER NAD 4.22961
448 1U8X NAD 4.23729
449 5KO1 6UY 4.24028
450 2B9W FAD 4.24528
451 5LQ8 GB 4.25532
452 2WJG GDP 4.25532
453 2I3G NAP 4.26136
454 2PWY SAH 4.26357
455 3VSE SAH 4.27136
456 5L4L NAP 4.27632
457 4TM3 FAD 4.28894
458 4M52 FAD 4.29185
459 4M52 M52 4.29185
460 5OVK NDP 4.29688
461 3SJU NDP 4.30108
462 4X9M FAD 4.30622
463 3OCP CMP 4.31655
464 5BSH PRO 4.33213
465 4J36 1HR 4.33735
466 4J36 FAD 4.33735
467 4MO2 FDA 4.34783
468 4MO2 FAD 4.34783
469 3T31 FAD 4.34783
470 3T31 DCQ 4.34783
471 2PK3 A2R 4.36137
472 2FWP CIT 4.37158
473 5T96 79J 4.38596
474 4FWE FAD 4.41176
475 4HSU FAD 4.41176
476 3GD4 FAD 4.41176
477 3GD4 NAD 4.41176
478 4GUT FAD 4.41176
479 4GUS FAD 4.41176
480 5W3K NDP 4.41176
481 5W3K 9TY 4.41176
482 4OPC PGT 4.41501
483 4OPC FDA 4.41501
484 1H82 FAD 4.44915
485 1H82 GZZ 4.44915
486 1WVG APR 4.45682
487 5CAE COA 4.47284
488 2O4C NAD 4.47368
489 2XWL CTP 4.4843
490 4KOA NDP 4.5045
491 1LDM NAD 4.55927
492 3GFB NAD 4.57143
493 4TSK NDP 4.57143
494 2CVQ NDP 4.58716
495 3BXO SAM 4.60251
496 2JB2 PHE 4.62185
497 2JB2 FAD 4.62185
498 4U8P UDP 4.62185
499 4U8P FDA 4.62185
500 3AYI HCI 4.62185
501 3AYI FAD 4.62185
502 1GPE FAD 4.62185
503 6ER9 FAD 4.62185
504 6ER9 NAP 4.62185
505 5E72 SAM 4.62428
506 3OFK SAH 4.62963
507 6AA8 NAD 4.63576
508 2FKA BEF 4.65116
509 5X62 SAH 4.6798
510 3Q3C NAD 4.68227
511 4Q9N NAI 4.69799
512 4JNA FAD 4.70588
513 5GM1 SAH 4.7138
514 5LOG SAH 4.72103
515 2NXE SAM 4.72441
516 1LDN NAD 4.74684
517 4GLL NAD 4.74777
518 4YCA NDP 4.7619
519 1YS4 NAP 4.80226
520 1HDG NAD 4.81928
521 2WJH FLC 4.81928
522 1V6A TRE 4.81928
523 1VM6 NAD 4.82456
524 5NII FAD 4.85437
525 4CNK FAD 4.85933
526 4RDH AMP 4.86111
527 4RDI ATP 4.86111
528 2CDU ADP 4.86726
529 2CDU FAD 4.86726
530 1LUA NAP 4.87805
531 5G4L NDP 4.8951
532 2NU8 COA 4.89691
533 5Z2L NDP 4.89796
534 2DFV NAD 4.89914
535 1I8T FAD 4.90463
536 3AXB PRO 4.91071
537 3AXB FAD 4.91071
538 1I36 NAP 4.92424
539 5Z20 NAI 4.92754
540 3QOX SAH 4.92958
541 5GT9 NAP 4.94297
542 1NE6 SP1 4.947
543 1F8G NAD 4.94792
544 1L7E NAI 4.94792
545 4TQG NDP 4.95356
546 4CQM NAP 4.98084
547 3DMH SAM 4.98688
548 3DMH GMP 4.98688
549 5L95 AMP 5
550 3SAO DBH 5
551 1VI2 NAD 5
552 1Q0S SAH 5.01931
553 2HNK SAH 5.02092
554 4FZV SAM 5.02092
555 2NVK NAP 5.04202
556 4C4A SAH 5.04202
557 2NVK FAD 5.04202
558 1P3D UMA 5.05263
559 1P31 EPU 5.05263
560 4D79 ATP 5.07246
561 4YRY NAD 5.07246
562 4YRY FAD 5.07246
563 4MDH NAD 5.08982
564 3BAZ NAP 5.1051
565 1YKF NAP 5.11364
566 2VT3 ATP 5.11628
567 1XHC FAD 5.17711
568 3WGT QSC 5.18732
569 3WGT FAD 5.18732
570 1NPD NAD 5.20833
571 1FWV SGA MAG FUC 5.22388
572 1TPY SAH 5.22648
573 3NYC IAR 5.24934
574 3NYC FAD 5.24934
575 1V8B NAD 5.2521
576 4USQ FAD 5.26316
577 3F8D FAD 5.26316
578 3NJ4 NAD 5.28736
579 3OZ2 FAD 5.28967
580 1H2B NAJ 5.29248
581 1C3V NDP 5.30612
582 5MPT SAH 5.31401
583 2EV9 NAP 5.32319
584 2EV9 SKM 5.32319
585 3G2O SAM 5.35117
586 4EMI FAD 5.36585
587 4EMI NAD 5.36585
588 5FAG PPI 5.36585
589 1KJ8 GAR 5.37084
590 3GF4 UPG 5.38462
591 3GF4 FAD 5.38462
592 4UP3 NDP 5.41401
593 4UP3 FAD 5.41401
594 3LZW FAD 5.42169
595 3LZW NAP 5.42169
596 6A0S HSE 5.42169
597 6A0S NDP 5.42169
598 3OID NDP 5.42636
599 2WA2 SAM 5.43478
600 6GAS FAD 5.43807
601 3O7W SAM 5.44218
602 6GAR FAD 5.44413
603 5UR0 NAD 5.44413
604 1GR0 NAD 5.44959
605 4YKG FAD 5.46218
606 4YKG NAD 5.46218
607 1JA9 NDP 5.47445
608 3H9E NAD 5.49133
609 5OCM NAP 5.49828
610 1UXG FUM 5.50162
611 1UXG NAD 5.50162
612 3GMB FAD 5.54217
613 3AB1 FAD 5.55556
614 3JQA NAP 5.55556
615 3JQB NAP 5.55556
616 3BMQ NAP 5.55556
617 3BMO NAP 5.55556
618 5JDI NAP 5.55556
619 3JQF NAP 5.55556
620 5XVH NAP 5.55556
621 4CM8 NAP 5.55556
622 5K6A NAP 5.55556
623 3JQ9 NAP 5.55556
624 4CM4 NAP 5.55556
625 5JCJ NAP 5.55556
626 4CMI NAP 5.55556
627 3JQG NAP 5.55556
628 5JDC NAP 5.55556
629 4CLR NAP 5.55556
630 3BMN NAP 5.55556
631 4CM9 NAP 5.55556
632 3JQ8 NAP 5.55556
633 3SJ7 NDP 5.55556
634 4CLO NAP 5.55556
635 4CME NAP 5.55556
636 3JQ7 NAP 5.55556
637 3WLE NAD 5.57185
638 1NVT NAP 5.57491
639 4DMG SAM 5.59796
640 4KIB SAH 5.60224
641 4EMJ FAD 5.60748
642 1A5Z NAD 5.64263
643 3NUG NAD 5.66802
644 2GMH FAD 5.67227
645 5VN0 FAD 5.67227
646 5VN0 NAI 5.67227
647 5OJL TXP 5.7047
648 3SSO SAH 5.72792
649 1L3I SAH 5.72917
650 2XYQ SAH 5.7377
651 4RPL FAD 5.76441
652 4RPL 3UC 5.76441
653 1GET NAP 5.77778
654 1GET FAD 5.77778
655 1KOL NAD 5.77889
656 3LXD FAD 5.78313
657 1UAY ADN 5.78512
658 2Q0L NAP 5.78778
659 2Q0L FAD 5.78778
660 5YU3 PRO 5.81395
661 5YU3 NAD 5.81395
662 3QJ4 FAD 5.84795
663 3WMX NAD 5.86592
664 1Q9I FAD 5.88235
665 1Q9I TEO 5.88235
666 4EDF UPG 5.88235
667 1BW9 NAD 5.89888
668 1BXG NAD 5.89888
669 4Y9D NAI 5.90164
670 3C3Y SAH 5.90717
671 1C1X NAD 5.91549
672 3QWI NAP 5.92593
673 3MB3 MB3 5.92593
674 2WD7 NAP 5.97015
675 4ZNO SUC 5.97015
676 3A25 SAM 5.98007
677 1X14 NAD 5.98504
678 2DBZ NAP 5.98802
679 6BII NAP 6.00601
680 3SHR CMP 6.02007
681 2BZG SAH 6.03448
682 2PXX SAH 6.04651
683 5K0A FAD 6.06061
684 4NEC SAH 6.06061
685 4BV6 FAD 6.09244
686 3GDN HBX 6.09244
687 3GDN FAD 6.09244
688 4USR FAD 6.09418
689 2VDV SAM 6.09756
690 6BWL NAD 6.09756
691 5TWB FAD 6.10465
692 5EZ7 FAD 6.12245
693 2Q7V FAD 6.15385
694 2QL9 CIT 6.18557
695 3GWZ SAH 6.23306
696 1E6E FAD 6.25
697 2RAB NAD 6.2635
698 2RAB FAD 6.2635
699 5N0J FAD 6.26781
700 1NW5 SAM 6.26959
701 1L1E SAH 6.27178
702 5T9E NAP 6.27306
703 3L9W AMP 6.2954
704 3L9W GSH 6.2954
705 5FJN FAD 6.30252
706 5FJN BE2 6.30252
707 1DL5 SAH 6.30915
708 5HXI FAD 6.33245
709 5HXI 5HN 6.33245
710 5ULP KB1 6.34328
711 4NBU NAI 6.4
712 4KRG SAH 6.43777
713 3GRU AMP 6.44068
714 5GZ6 NDP 6.44172
715 5GZ6 7C3 6.44172
716 2CUL FAD 6.46552
717 3CBG SAH 6.46552
718 4KRI SAH 6.46651
719 5AYV NAP 6.47249
720 5AYV KPL 6.47249
721 3ITJ FAD 6.50888
722 3ITJ CIT 6.50888
723 3RNM FAD 6.51261
724 5J5Z FAD 6.51261
725 2XVM SAH 6.53266
726 4O0L NDP 6.54545
727 5I39 FAD 6.61765
728 4NBT NAD 6.66667
729 1JNR FAD 6.72269
730 2R4J FAD 6.72269
731 2R4J 13P 6.72269
732 1QMG APX 6.72269
733 1DCP HBI 6.73077
734 1NVM NAD 6.73077
735 4II2 ATP 6.74847
736 3ORF NAD 6.77291
737 1F3L SAH 6.85358
738 1LTH NAD 6.89655
739 1GEE NAD 6.89655
740 3FG2 FAD 6.93069
741 2RGH FAD 6.93277
742 1VKO NAD 6.93277
743 6ACS CIT 6.97674
744 1RP0 AHZ 7.04225
745 2YVJ NAI 7.10784
746 2YVF NAD 7.10784
747 2YVF FAD 7.10784
748 2YVJ FAD 7.10784
749 5U5G NAP 7.11864
750 2RGO FAD 7.14286
751 1D4D FAD 7.14286
752 2F1K NAP 7.16846
753 1H5Q NAP 7.16981
754 5J60 FAD 7.1875
755 1ELI PYC 7.19794
756 1SAY PYR 7.20222
757 1O5I NAD 7.22892
758 2JAH NDP 7.28745
759 1SOW NAD 7.31707
760 5HV7 RBL 7.33945
761 1D8C GLV 7.35294
762 3D3W NAP 7.37705
763 1PR9 NAP 7.37705
764 4XDY NAI 7.39645
765 2YKL NLD 7.40741
766 1GV0 NAD 7.41935
767 4GKV NAD 7.44048
768 5LOL GSH 7.44186
769 2RGJ FAD 7.46269
770 2Q1W NAD 7.50751
771 3P2E SAH 7.55556
772 3RKR NAP 7.63359
773 5N2I NAP 7.75862
774 1JQ3 AAT 7.77027
775 4YNU LGC 7.77311
776 4YNU FAD 7.77311
777 4GYS MLI 7.77311
778 1HKU NAD 7.82123
779 2PZM UDP 7.87879
780 2PZM NAD 7.87879
781 5A1T NAI 7.91789
782 5A1T OXM 7.91789
783 3KU0 ADE 7.96813
784 3LAD FAD 7.98319
785 3H4V NAP 7.98611
786 5YF1 SFG 8.01105
787 1KYQ NAD 8.0292
788 5O4J SAH 8.0292
789 5O4J PJL 8.0292
790 5O4J 9KH 8.0292
791 3G89 SAM 8.03213
792 1D1T NAD 8.0429
793 3FPF MTA 8.05369
794 3FPF TNA 8.05369
795 1Z82 NDP 8.0597
796 5JCA FAD 8.09859
797 5JCA NDP 8.09859
798 3HVJ 705 8.1448
799 6BQ6 TER 8.1571
800 6F5Z SAH 8.19672
801 5H81 NAP 8.22622
802 1YJQ NAP 8.25082
803 5X20 NAD 8.33333
804 6HQD SRT 8.33333
805 1SNN 5RP 8.37004
806 1FL2 FAD 8.3871
807 1REO FAD 8.40336
808 1DSS NAD 8.40841
809 1E3W NAD 8.42912
810 4TXI FAD 8.45528
811 1E6W NAD 8.46154
812 4YSX FAD 8.51064
813 1JG3 ADN 8.51064
814 1KEV NDP 8.54701
815 5D4V SAH 8.58209
816 5W7M SAH 8.65385
817 4OM8 NAD 8.73786
818 1R18 SAH 8.81057
819 3NT6 FAD 8.82353
820 3NTA FAD 8.82353
821 4J56 FAD 8.82353
822 3C6K SPD 8.82353
823 3C6K MTA 8.82353
824 1ZHS NAG NAG BMA MAN MAN 8.84956
825 3DUW SAH 8.96861
826 5BW4 SAM 8.98876
827 2GUD BMA 9.01639
828 2GUE NAG 9.01639
829 2NUO BGC 9.01639
830 2HYR BGC GLC 9.01639
831 2HYQ MAN MAN 9.01639
832 2NU5 NAG 9.01639
833 2GUD MAN 9.01639
834 2GUC MAN 9.01639
835 5DNK SAH 9.03361
836 3HDY FDA 9.06801
837 3HDY FAD 9.06801
838 3HDY GDU 9.06801
839 2Q46 NAP 9.09091
840 6FP4 FAD 9.2437
841 2JHP SAH 9.2437
842 6FP4 E1T 9.2437
843 3NTD FAD 9.2437
844 5U8U FAD 9.2437
845 5NUF NAD 9.33735
846 5NUE NAD 9.33735
847 1SC6 NAD 9.40594
848 2C7G ODP 9.42982
849 2C7G FAD 9.42982
850 3OA2 NAD 9.74843
851 1NM5 NAD 9.85222
852 5G6U TRP 9.96169
853 4NTD FAD 10
854 4YMH SAH 10
855 5Z21 NAI 10.0559
856 5EES NAP 10.1215
857 5JCM FAD 10.1996
858 5JCM ISD 10.1996
859 5JCM NAD 10.1996
860 4B4U NAP 10.231
861 3H2B SAH 10.3448
862 4QTU SAM 10.3704
863 4AZW SAM 10.4034
864 2BRY FAD 10.4628
865 1TDF FAD 10.7595
866 1TDF NAP 10.7595
867 2EWM NAD 10.8434
868 2G30 ALA ALA PHE 10.8527
869 1KO8 6PG 10.8571
870 2Q1S NAI 10.8753
871 1C3M MAN MAN 10.8844
872 5E9W SAH 10.8974
873 5E8J SAH 10.8974
874 4ZRN NAD 10.8974
875 2HMT NAI 11.1111
876 3K7M FAD 11.1369
877 1X7D NAD 11.1429
878 1G60 SAM 11.1538
879 1GVF PGH 11.1888
880 1W8D NAP 11.2583
881 1W73 NAP 11.2583
882 1Q1R FAD 11.3689
883 2OOR NAD 11.4943
884 6GNC FAD 11.5646
885 1W6U NAP 11.5894
886 3PNA CMP 11.6883
887 6ECU SAH 11.7089
888 6ECW SAH 11.746
889 3OF1 CMP 11.7886
890 2GAG NAD 11.8519
891 2GAG FOA 11.8519
892 2GAG FAD 11.8519
893 1XCL SAH 11.9149
894 3MAG SAH 13.0293
895 5W7K SAH 13.141
896 1WPQ NAD 13.1805
897 5C8W PCG 13.2867
898 3MCT SAH 13.468
899 1LSS NAD 13.5714
900 1EJ0 SAM 13.8889
901 1P1C SAH 14.0704
902 2YX1 SFG 14.2857
903 1LVL NAD 14.4105
904 1LVL FAD 14.4105
905 3LCC SAH 14.4681
906 3E1T FAD 14.916
907 1VDC FAD 15.3153
908 6GNA FAD 15.9722
909 3IWD M2T 16.129
910 3DXY SAM 16.5138
911 5YEC ATP 16.8067
912 5EOW FAD 17.037
913 1QAN SAH 17.2131
914 5BVA FAD 17.6039
915 3CTY FAD 18.4953
916 5EIN NAP 18.5185
917 5TUK FAD 18.8725
918 3AD8 NAD 20.202
919 3AD8 PYC 20.202
920 3AD8 FAD 20.202
921 5VNF VAL THR SER VAL VAL 20.3822
922 5MIT FAD 21.7125
923 5MIT NAP 21.7125
924 5E1M SAH 23.6515
925 5EVY FAD 23.7443
926 3QFA FAD 24.1379
927 1PN0 IPH 26.6807
928 1PN0 FAD 26.6807
929 5BUK FAD 28
930 5Y77 FAD 29.8097
931 4BJZ P3A 30.8962
932 4BJZ FAD 30.8962
933 5MZI FAD 31.0195
934 5MZI FYK 31.0195
935 4GQB 0XU 31.8182
936 2F5Z FAD 32.8125
937 4M38 SAH 33.3333
938 5TUF TDC 33.7408
939 5TUF FAD 33.7408
940 2Y6Q FAD 33.9196
941 2Y6Q I7T 33.9196
942 4EIP FAD 34.4538
943 4EIP K2C 34.4538
944 5FA5 MTA 35
945 3IHG FAD 35.084
946 3IHG VAK 35.084
947 2DKH FAD 35.2941
948 2DKH 3HB 35.2941
949 6FHO FAD 35.3383
950 1YKJ FAD 38.3249
951 1YKJ PHB 38.3249
952 6AIN FAD 39.2345
953 5BRT FAD 41.3866
954 5BRT CH9 41.3866
Pocket No.: 2; Query (leader) PDB : 5KOX; Ligand: RFP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5kox.bio1) has 58 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 5KOX; Ligand: FAD; Similar sites found with APoc: 933
This union binding pocket(no: 3) in the query (biounit: 5kox.bio1) has 54 residues
No: Leader PDB Ligand Sequence Similarity
1 3U31 NAD 1.03448
2 1CDO NAD 1.06952
3 5Z75 NAD 1.22324
4 2PT9 S4M 1.24611
5 2PT9 2MH 1.24611
6 5OC1 FAD 1.2605
7 1Z45 NAD 1.2605
8 1PJS NAD 1.31291
9 1YQZ FAD 1.36986
10 2Z49 AMG 1.38889
11 2I7C AAT 1.41343
12 5A2Z GTP 1.47059
13 3ULK NDP 1.47059
14 1U1I NAD 1.53061
15 5K4W NAI 1.55763
16 5K4W THR 1.55763
17 5ERG SAM 1.56658
18 2D2I NAP 1.57895
19 3G5S FAD 1.58014
20 1E3I CXF 1.59574
21 1GUZ NAD 1.6129
22 1FP1 SAH 1.6129
23 2JJQ SAH 1.64706
24 5JE8 NAD 1.65563
25 1DJN ADP 1.68067
26 5DXA SFG 1.7192
27 5DX8 SFG 1.7192
28 5DWQ SFG 1.7192
29 5DX1 SFG 1.7192
30 5DX0 SFG 1.7192
31 5THY SAH 1.7284
32 5THZ SAH 1.7284
33 2B4R AES 1.73913
34 2B4R NAD 1.73913
35 4M37 SAH 1.74927
36 5KOK SAH 1.76322
37 3B20 NAD 1.76991
38 3B1J NAD 1.76991
39 4MP8 NAD 1.76991
40 4MP8 MLI 1.76991
41 4KVL PLM 1.77134
42 2HK9 ATR 1.81818
43 2HK9 NAP 1.81818
44 5KVS NAP 1.81818
45 4HXY NDP 1.82648
46 3OJO NAD 1.85615
47 4R5M NAP 1.8617
48 4R5M 4NO 1.8617
49 2FK8 SAM 1.88679
50 1PS9 FAD 1.89076
51 1PS9 NAP 1.89076
52 6D6Y SAH 1.89076
53 1GZ4 ATP 1.89076
54 5JJR SAH 1.89076
55 2GZ3 NAP 1.91257
56 1KYZ SAH 1.91781
57 1FLJ GSH 1.92308
58 4JK3 NAD 1.9305
59 4J4H 1J1 1.9305
60 4J4H NAI 1.9305
61 4R6W SAH 1.93798
62 4OBW SAM 1.94553
63 3CIF NAD 1.94986
64 3CIF G3H 1.94986
65 1EBF NAD 1.95531
66 3DAG FEG 1.95531
67 2X6T NAP 1.96078
68 2O07 MTA 1.97368
69 2O07 SPD 1.97368
70 1O6Z NAD 1.9802
71 6GKV SAH 1.9943
72 5N6C NAD 2
73 1E5Q NDP 2
74 2YYY NAP 2.04082
75 1LC3 NAD