-->
Receptor
PDB id Resolution Class Description Source Keywords
5LUN 1.08 Å NON-ENZYME: OTHER ETHYLENE FORMING ENZYME FROM PSEUDOMONAS SYRINGAE PV. PHASEO P1 ULTRA-HIGH RESOLUTION CRYSTAL FORM IN COMPLEX WITH IRON,O XALYLGLYCINE AND ARGININE PSEUDOMONAS SAVASTANOI PV. PHASEOLICOLORGANISM_TAXID: 319 2-OXOGLUTARATE AND FERROUS IRON DEPENDENT OXYGENASE ETHYLENFORMING DOUBLE STRANDED BETA HELIX OXIDOREDUCTASE
Ref.: STRUCTURAL AND STEREOELECTRONIC INSIGHTS INTO OXYGENASE-CATALYZED FORMATION OF ETHYLENE FROM 2-OXOGLUTARATE. PROC. NATL. ACAD. SCI. V. 114 4667 2017 U.S.A.
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FE A:401;
C:401;
D:401;
B:401;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
55.845 Fe [Fe+3...
OGA B:402;
D:402;
C:402;
A:402;
Valid;
Valid;
Valid;
Valid;
Atoms found LESS than expected: % Diff = 0;
Atoms found LESS than expected: % Diff = 0;
Atoms found LESS than expected: % Diff = 0;
Atoms found LESS than expected: % Diff = 0;
submit data
147.086 C4 H5 N O5 C(C(=...
ARG A:403;
C:403;
D:403;
B:403;
Valid;
Valid;
Valid;
Valid;
Atoms found LESS than expected: % Diff = 0;
Atoms found LESS than expected: % Diff = 0;
Atoms found LESS than expected: % Diff = 0;
Atoms found LESS than expected: % Diff = 0;
submit data
175.209 C6 H15 N4 O2 C(C[C...
GOL A:404;
B:405;
B:404;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5LUN 1.08 Å NON-ENZYME: OTHER ETHYLENE FORMING ENZYME FROM PSEUDOMONAS SYRINGAE PV. PHASEO P1 ULTRA-HIGH RESOLUTION CRYSTAL FORM IN COMPLEX WITH IRON,O XALYLGLYCINE AND ARGININE PSEUDOMONAS SAVASTANOI PV. PHASEOLICOLORGANISM_TAXID: 319 2-OXOGLUTARATE AND FERROUS IRON DEPENDENT OXYGENASE ETHYLENFORMING DOUBLE STRANDED BETA HELIX OXIDOREDUCTASE
Ref.: STRUCTURAL AND STEREOELECTRONIC INSIGHTS INTO OXYGENASE-CATALYZED FORMATION OF ETHYLENE FROM 2-OXOGLUTARATE. PROC. NATL. ACAD. SCI. V. 114 4667 2017 U.S.A.
Members (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 5V32 - MLT C4 H6 O5 C([C@H](C(....
2 5VKA - AKG C5 H6 O5 C(CC(=O)O)....
3 5V2T - TLA C4 H6 O6 [C@@H]([C@....
4 5VKB - AAR C6 H16 N5 O C(C[C@@H](....
5 5V31 - ARG C6 H15 N4 O2 C(C[C@@H](....
6 5V2X - AKG C5 H6 O5 C(CC(=O)O)....
7 5LUN - OGA C4 H5 N O5 C(C(=O)O)N....
8 5V2Y - ARG C6 H15 N4 O2 C(C[C@@H](....
9 5V2Z - ARG C6 H15 N4 O2 C(C[C@@H](....
10 5V34 - ARG C6 H15 N4 O2 C(C[C@@H](....
11 5MOF - AKG C5 H6 O5 C(CC(=O)O)....
70% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5V32 - MLT C4 H6 O5 C([C@H](C(....
2 5VKA - AKG C5 H6 O5 C(CC(=O)O)....
3 5V2T - TLA C4 H6 O6 [C@@H]([C@....
4 5VKB - AAR C6 H16 N5 O C(C[C@@H](....
5 5V31 - ARG C6 H15 N4 O2 C(C[C@@H](....
6 5V2X - AKG C5 H6 O5 C(CC(=O)O)....
7 5LUN - OGA C4 H5 N O5 C(C(=O)O)N....
8 5V2Y - ARG C6 H15 N4 O2 C(C[C@@H](....
9 5V2Z - ARG C6 H15 N4 O2 C(C[C@@H](....
10 5V34 - ARG C6 H15 N4 O2 C(C[C@@H](....
11 5MOF - AKG C5 H6 O5 C(CC(=O)O)....
50% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 5V32 - MLT C4 H6 O5 C([C@H](C(....
2 5VKA - AKG C5 H6 O5 C(CC(=O)O)....
3 5V2T - TLA C4 H6 O6 [C@@H]([C@....
4 5VKB - AAR C6 H16 N5 O C(C[C@@H](....
5 5V31 - ARG C6 H15 N4 O2 C(C[C@@H](....
6 5V2X - AKG C5 H6 O5 C(CC(=O)O)....
7 5LUN - OGA C4 H5 N O5 C(C(=O)O)N....
8 5V2Y - ARG C6 H15 N4 O2 C(C[C@@H](....
9 5V2Z - ARG C6 H15 N4 O2 C(C[C@@H](....
10 5V34 - ARG C6 H15 N4 O2 C(C[C@@H](....
11 5MOF - AKG C5 H6 O5 C(CC(=O)O)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: OGA; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 OGA 1 1
2 AAC 0.461538 0.827586
Ligand no: 2; Ligand: ARG; Similar ligands found: 42
No: Ligand ECFP6 Tc MDL keys Tc
1 ARG 1 1
2 DAR 1 1
3 CIR 0.735294 0.763158
4 AAR 0.705882 0.783784
5 ILO 0.615385 0.783784
6 3AR 0.595238 0.891892
7 4JK 0.585366 0.789474
8 NMM 0.585366 0.888889
9 VUR 0.585366 0.810811
10 HAR 0.585366 0.780488
11 VIO 0.581395 0.769231
12 WT2 0.571429 0.805556
13 DA2 0.55814 0.744186
14 2MR 0.545455 0.864865
15 2YH 0.545455 0.65
16 3KJ 0.545455 0.680851
17 1KJ 0.533333 0.744186
18 JM2 0.533333 0.731707
19 NRG 0.521739 0.622642
20 RPI 0.521739 0.64
21 2YJ 0.521739 0.619048
22 API 0.515152 0.611111
23 LN6 0.510638 0.725
24 HRG 0.5 0.941176
25 JM7 0.5 0.731707
26 2KJ 0.489796 0.727273
27 D20 0.489796 0.744186
28 AS1 0.489796 0.8
29 ORN 0.472222 0.757576
30 JM8 0.470588 0.714286
31 JM6 0.470588 0.697674
32 JM4 0.470588 0.697674
33 LYS ARG LYS ARG LYS ARG LYS ARG 0.463415 0.848485
34 MLZ 0.463415 0.65
35 JM5 0.461538 0.714286
36 DLY 0.447368 0.735294
37 DAB 0.441176 0.685714
38 LYS 0.435897 0.764706
39 0TF 0.428571 0.619048
40 2YG 0.42 0.619048
41 PG3 0.416667 0.756757
42 6CL 0.414634 0.638889
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5LUN; Ligand: ARG; Similar sites found with APoc: 40
This union binding pocket(no: 1) in the query (biounit: 5lun.bio3) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 6G0X RAM GLC GLA NAG NDG NAG 1.42045
2 4DM8 REA 1.49813
3 3KMR EQN 1.50376
4 4IPE ANP 1.70455
5 6ECU SAH 1.89873
6 3WDM ADN 1.91571
7 2LBD REA 2.24719
8 5VFC 9BA 2.2508
9 4QWT ACD 2.27273
10 3NRR D16 2.27273
11 1FCZ 156 2.55319
12 3OPT AKG 3.125
13 1AJQ SPA 3.34928
14 2Q8E OGA 3.40909
15 4ZLU ADP 3.40909
16 4ZLU 4PW 3.40909
17 2OS2 OGA 3.40909
18 2P5B OGA 3.40909
19 2YBP 2HG 3.40909
20 6ECT SAM 3.42679
21 1UWK URO 3.69318
22 1UWK NAD 3.69318
23 3GD4 FAD 3.7182
24 4CUB GAL NAG 3.82514
25 1HG4 LPP 4.30108
26 2AMT GPP 4.40252
27 4X6F 3XU 4.7619
28 3BNK FMN 6.12245
29 1TZJ A3B 6.21302
30 1JW0 GUA 6.96203
31 2I7C AAT 7.06714
32 4XJC TTP 7.34463
33 5MBC FMN 7.38636
34 3ATY FMN 7.67045
35 3H0A D30 7.89474
36 5JBX MLI 8.04598
37 5V7I 8Z1 8.23864
38 1YRO GDU 10.5691
39 1ZDQ MSM 11.0119
40 2ZFZ ARG 37.9747
Pocket No.: 2; Query (leader) PDB : 5LUN; Ligand: OGA; Similar sites found with APoc: 255
This union binding pocket(no: 2) in the query (biounit: 5lun.bio3) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1YKJ PHB 1.13636
2 1YKJ FAD 1.13636
3 4QDF 30Q 1.42045
4 4QDC ASD 1.42045
5 3VHH VHH 1.62602
6 6GIN IR2 1.66113
7 2VFT SOR 1.70455
8 3E8N VRA 1.75953
9 3E8N ATP 1.75953
10 4MP8 NAD 1.76991
11 4MP8 MLI 1.76991
12 5Y72 DST 1.79104
13 5BQS 4VN 1.85759
14 6EOZ AKG 1.94805
15 6EOZ 58K 1.94805
16 5A3T MMK 1.98864
17 4CCK OGA 1.98864
18 4CCO OGA 1.98864
19 4Y3O OGA 1.98864
20 5FWJ MMK 1.98864
21 2PNC CLU 1.98864
22 6EXF LYS 1.98864
23 3DER ALA LYS 2.02899
24 5GLT BGC GAL NAG GAL 2.11268
25 5IVE 6E8 2.12121
26 1PS6 4TP 2.13415
27 3QP8 HL0 2.17391
28 1LSH PLD 2.19436
29 2JIG PD2 2.23214
30 4NV7 COA 2.24359
31 2A1X AKG 2.27273
32 1LLF F23 2.27273
33 1ZHX HC3 2.27273
34 5U3B 7TD 2.34114
35 1KGI T4A 2.3622
36 2YAK OSV 2.45614
37 3SAO NKN 2.5
38 5K8B PDG 2.55682
39 4X7Q 3YR 2.5641
40 5NCJ HL5 2.61194
41 5NCJ SIN 2.61194
42 5EQU 5R6 2.62295
43 5EQU AKG 2.62295
44 5HQ0 LZ9 2.64901
45 5ML3 DL3 2.68456
46 5UR6 8KM 2.76243
47 2E56 MYR 2.77778
48 1OS7 AKG 2.82686
49 1OS7 TAU 2.82686
50 4BR5 ANP 2.84091
51 5HMR FDZ 2.84091
52 5N9T 8QQ 2.84091
53 3TYZ XHP 2.85714
54 4N14 WR7 2.86624
55 1QY1 PRZ 2.87356
56 1T27 PCW 2.95203
57 5I0U DCY 3
58 4NAO AKG 3.06748
59 5JWP AKG 3.125
60 2Y0I AKG 3.125
61 2OG7 SIN 3.125
62 4BG1 OGA 3.125
63 4BG1 IVL 3.125
64 2RKV COA 3.125
65 2RKV ZBA 3.125
66 5X7Q GLC GLC GLC GLC 3.125
67 5X7Q GLC GLC GLC GLC GLC 3.125
68 4TW7 37K 3.125
69 3P3N AKG 3.15186
70 4B7E OGA 3.15186
71 2XUM OGA 3.15186
72 2WA4 069 3.15186
73 1J3R 6PG 3.15789
74 3T03 3T0 3.16901
75 3M94 M7M 3.1746
76 2ZMF CMP 3.1746
77 2GC0 PAN 3.19149
78 5HV0 AKG 3.22581
79 5LXB 7A9 3.30579
80 5EW9 5VC 3.32103
81 3FW3 ETS 3.38346
82 5F3I 5UJ 3.40909
83 5FWE OGA 3.40909
84 2YBP 2HG 3.40909
85 5LY2 OGA 3.40909
86 2Q8E OGA 3.40909
87 2OS2 OGA 3.40909
88 2P5B OGA 3.40909
89 2AE2 PTO 3.46154
90 4ZXA H8N 3.57143
91 4OCT AKG 3.6036
92 6FXR AKG 3.69318
93 4ZAC 4LU 3.69318
94 4WOE ADP 3.69318
95 2IUW AKG 3.78151
96 3E2M E2M 3.78378
97 5YBL AKG 3.82166
98 4YGF AZM 3.84615
99 1SGJ OAA 3.87324
100 4D06 NAR 3.88693
101 1WUB OTP 3.93258
102 4RFR RHN 3.94089
103 5UWA 8ND 3.94089
104 5OX6 A1Z 3.96825
105 2WBP SIN 3.97727
106 2WBP ZZU 3.97727
107 4V24 GYR 3.97727
108 2ET1 GLV 3.9801
109 5TFZ 7BC 4
110 1DRY AKG 4.01235
111 1DRY AAG 4.01235
112 3SCH TB6 4.0404
113 3HQR OGA 4.06504
114 5APK 76E 4.15094
115 3PFG SAM 4.18251
116 3PFG TLO 4.18251
117 5KO1 6UY 4.24028
118 4IE6 UN9 4.26136
119 4UF0 MMK 4.26136
120 1TT8 PHB 4.26829
121 3NV3 GAL NAG MAN 4.34783
122 4M26 AKG 4.3956
123 4M26 ZZU 4.3956
124 4M26 SIN 4.3956
125 1DMY AZM 4.43548
126 6GNO XDI 4.44444
127 5LJB RTL 4.44444
128 1N5S ADL 4.46429
129 2FCU AKG 4.47284
130 5FP3 3JI 4.54545
131 6F6D AKG 4.54545
132 1MDC PLM 4.54545
133 1YKD CMP 4.54545
134 1XPK CAA 4.54545
135 1XPM CAA 4.54545
136 2HFN FMN 4.57516
137 4JZR 4JR 4.62963
138 5YU3 NAD 4.65116
139 5YU3 PRO 4.65116
140 6F4T OGA 4.70588
141 6D6L FY4 4.70588
142 1GQG DCD 4.85714
143 1X0P FAD 4.8951
144 2XMY CDK 5.03356
145 3P7N FMN 5.03876
146 3FW4 CAQ 5.05618
147 1DZK PRZ 5.09554
148 4O9S 2RY 5.11628
149 5ZM4 AKG 5.22876
150 5ZM4 9FU 5.22876
151 4WO4 JLS 5.31401
152 4XCB HY0 5.36398
153 4XCB AKG 5.36398
154 5DEY 59T 5.38721
155 3N9P OGA 5.39773
156 3PUR 2HG 5.39773
157 3N9Q OGA 5.39773
158 3N9O OGA 5.39773
159 4L4J NAG NAG BMA MAN NAG 5.42986
160 1NX4 AKG 5.49451
161 3VQ2 LP4 LP5 MYR DAO 5.55556
162 6MPT C30 5.59441
163 4C2V YJA 5.61404
164 6D61 4AA 5.64103
165 4COQ SAN 5.66802
166 3KV4 OGA 5.68182
167 4PFC 2QX 5.68182
168 4LA7 A1O 5.69948
169 3AGC RCC 5.7971
170 4Z28 BTN 5.97015
171 2PR5 FMN 6.06061
172 4WUJ FMN 6.12245
173 4LIT AKG 6.25
174 4UEC MGT 6.52174
175 4BXF AKG 6.53409
176 2GJ5 VD3 6.79012
177 3FW9 SLX 6.81818
178 5UC4 83S 6.81818
179 3SRV S19 6.85921
180 3SLS 77D 6.90789
181 2D6M LBT 6.91824
182 4QM9 CYS 6.93642
183 5JSP DQY 6.96517
184 2Q8Y GLN TYR PHE MET TPO GLU PTR VAL ALA 7.05394
185 1UNB AKG 7.07396
186 1UNB PN1 7.07396
187 6FUL E7Z 7.10227
188 3AVR OGA 7.10227
189 5XVG 8FX 7.16724
190 2RDQ AKG 7.29167
191 4OJ8 AKG 7.50853
192 4OJ8 2TQ 7.50853
193 1GT4 UNA 7.54717
194 4NPL AKG 7.6
195 3AJH BL3 7.66129
196 5NW7 9C2 7.95455
197 4NW6 2NS 8.04954
198 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 8.08081
199 3RUG DB6 8.08081
200 3G08 FEE 8.08081
201 3QUZ QUV 8.08081
202 1LVG 5GP 8.08081
203 5FKP 6UL 8.08081
204 4X5S AZM 8.18966
205 6F6J CUW 8.37989
206 6F6J SIN 8.37989
207 2UZ2 BTN 8.46154
208 1REQ DCA 8.80682
209 1OIJ AKG 8.9701
210 1OIK C26 8.9701
211 1OIK AKG 8.9701
212 5FP4 YC8 8.98204
213 1OLM VTQ 9.375
214 4AZP A9M 9.42029
215 3EW2 BTN 9.62963
216 4G31 0WH 9.699
217 3RGA LSB 9.89399
218 4ZSI 4R1 9.94152
219 3A6T 8OG 10.0775
220 5C5T AKG 10.0877
221 6BYM HC3 10.3448
222 4BCS BTN 10.4
223 5T46 MGP 10.6061
224 5TZO 7V7 10.6383
225 4WVW SLT 11.1111
226 3PDT ADP 11.2727
227 3G5D 1N1 11.5385
228 4P7X AKG 11.6438
229 4P7X YCP 11.6438
230 4WW8 VD9 12.5475
231 5XEG AKG 12.5541
232 4RLT FSE 13.6054
233 2AG4 LP3 15.2439
234 4G7A AZM 15.3226
235 4R3U 3KK 15.8228
236 4R3U 3HC 15.8228
237 3STK PLM 15.9091
238 1GP6 SIN 16.1932
239 1GP6 QUE 16.1932
240 1GP6 DH2 16.1932
241 1WBI BTN 17.0543
242 1LFO OLA 18.75
243 5ABX MGP 19.5122
244 1H2M OGA 21.1538
245 5FLJ QUE 21.5054
246 4EES FMN 21.7391
247 1YRX FMN 23.1405
248 4QXB OGA 23.5294
249 5O9W AKG 24.7159
250 5B09 4MX 25
251 1ODM ASV 25.6798
252 4CCN OGA 25.7143
253 1H2K OGA 26.8293
254 5C3R HMU 34.1108
255 5C3R AKG 34.1108
Pocket No.: 3; Query (leader) PDB : 5LUN; Ligand: OGA; Similar sites found with APoc: 183
This union binding pocket(no: 3) in the query (biounit: 5lun.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 6B79 ORA None
2 3TTI KBI 1.13636
3 3OV6 MK0 1.70455
4 6C6O ENG 1.70455
5 2OO8 RAJ 1.89274
6 1OFL NGK GCD 1.98864
7 4BG4 ADP 1.98864
8 5GVL GI8 1.98864
9 5GVL PLG 1.98864
10 3A5Y KAA 2.02899
11 3ZXE PGZ 2.25564
12 3E9I XAH 2.27273
13 2GMH UQ5 2.27273
14 3DLG GWE 2.27273
15 4USF 6UI 2.30263
16 1F9V ADP 2.30548
17 3TCT 3MI 2.3622
18 3VBK COA 2.43902
19 2XK9 XK9 2.48447
20 1HXD BTN 2.49221
21 3SAO DBH 2.5
22 2HK9 SKM 2.54545
23 1VA6 ADP 2.55682
24 1VA6 P2S 2.55682
25 2RCU BUJ 2.55682
26 2XGT NSS 2.55682
27 4DXD 9PC 2.55682
28 1M15 ADP 2.55682
29 1M15 ARG 2.55682
30 3U2U UDP 2.6616
31 2X34 UQ8 2.76243
32 5UIU 8CG 2.78638
33 3BF1 ADP 2.81124
34 5LRT ADP 2.84091
35 2GVJ DGB 2.84091
36 4HWS 1B3 2.84091
37 2I7N ACO 2.84091
38 2J3M PRI 2.84091
39 3B6R ADP 2.84091
40 1U6R ADP 2.84091
41 4XTX 590 2.96296
42 1UYY BGC BGC 3.05344
43 2QIA U20 3.05344
44 4Z87 GDP 3.125
45 1X54 4AD 3.125
46 2RG0 CTT 3.125
47 4HWT 1B2 3.125
48 2QPU QPU 3.125
49 3HXU A5A 3.125
50 1TOI HCI 3.125
51 4J7H TLO 3.125
52 3NKS ACJ 3.125
53 2QPU QPS 3.125
54 1B7Y FYA 3.125
55 3RG9 NDP 3.33333
56 4HBM 0Y7 3.33333
57 3E5A VX6 3.35821
58 2XCG XCG 3.40909
59 4OYA 1VE 3.40909
60 5LY1 PPI 3.40909
61 3JU6 ANP 3.40909
62 5A0U CHT 3.40909
63 2Y6O 1N1 3.43643
64 6C0T EE4 3.45821
65 5VC5 96M 3.46021
66 4QMN DB8 3.54839
67 4YBN FAD 3.57143
68 1J3I WRA 3.57143
69 5W10 CMP 3.58974
70 4DQ2 BTX 3.65854
71 4RF7 ARG 3.69318
72 1YFS ALA 3.69318
73 3A16 PXO 3.69318
74 3JQ3 ADP 3.69318
75 3NZ1 3NY 3.83142
76 3I3X U22 3.861
77 5MJA 7O3 3.93443
78 6E1Q CFA 3.97727
79 4B2Z P5S 3.97727
80 5JKG 6LF 4.18006
81 1ELI PYC 4.26136
82 5AE2 FAD 4.26136
83 5AE2 FYC 4.26136
84 4EWH T77 4.36364
85 5CDH TLA 4.46429
86 6ALW BMJ 4.51389
87 2IU8 PLM 4.54545
88 4MPO AMP 4.57516
89 5D48 L96 4.60526
90 3GAY P6T 4.64396
91 5VNF VAL THR SER VAL VAL 4.82955
92 5U98 1KX 5.05051
93 5WL1 CUY 5.05051
94 5WL1 D3D 5.05051
95 6EWZ APC 5.06329
96 2YKL NLD 5.09259
97 3ITA AIC 5.11364
98 1VRP ADP 5.11364
99 3EFS BTN 5.15021
100 4N70 2HX 5.18293
101 3A5Z KAA 5.2356
102 5GZ9 ANP 5.2459
103 2YC5 6BC 5.26316
104 6GWR FEW 5.39683
105 2VL1 GLY GLY 5.39773
106 1ADO 13P 5.39773
107 5EXW 7DT 5.39773
108 1X7D ORN 5.42857
109 1W62 PYC 5.55556
110 5KJW 53C 5.68182
111 4DHY S41 5.68182
112 5LIA 6XN 5.68182
113 2WKQ FMN 5.72289
114 3EM0 CHD 5.7971
115 5NKB 8ZT 5.88235
116 2DQU CPD 5.93607
117 1G51 AMO 5.96591
118 6E08 NAP 5.96591
119 1ERB ETR 6.01093
120 3CBC DBS 6.06061
121 5VCV 1N1 6.10932
122 5HWV MBN 6.15385
123 1FHX 4IP 6.20155
124 1S4M LUM 6.48464
125 5W4W 9WG 6.53409
126 4KBA 1QM 6.53409
127 3SXS PP2 6.71642
128 5L2R MLA 6.81818
129 1KZN CBN 6.82927
130 4BVA T3 6.86567
131 5OCG 9R5 6.87831
132 4MOB ADP 6.92771
133 4F4P 0SB 6.95971
134 4R38 RBF 7.14286
135 2Z77 HE7 7.19424
136 2X32 OTP 7.26257
137 3IWD M2T 7.35294
138 4NS3 NAD 7.38636
139 6FA4 D1W 7.51445
140 5FUI APY 7.57576
141 3GC8 B45 7.67045
142 1QKQ MAN 7.74648
143 4TWP AXI 7.74908
144 1V3S ATP 7.75862
145 4QAC KK3 7.8341
146 6B3V ANP 7.89474
147 6B3V 7DQ 7.89474
148 4JLS 3ZE 7.89474
149 1IND EOT 7.90698
150 2Z3U CRR 7.95455
151 4IEN GDP 7.97546
152 4PXL NAD 8.23864
153 5A89 FMN 8.33333
154 5A89 ADP 8.33333
155 5HCY 60D 8.45921
156 4CS4 AXZ 8.75912
157 4CS4 ANP 8.75912
158 3HAZ NAD 8.80682
159 4F7E 0SH 8.83392
160 1WPY BTN 9.3617
161 5UKL SIX 9.375
162 2H8H H8H 9.375
163 5W71 PLP 9.375
164 5W71 9YM 9.375
165 1KTG AMP 10.1449
166 1HZP DAO 10.1493
167 3VRY B43 10.5114
168 1PZO CBT 10.6464
169 5VKM GAL SIA 10.7955
170 5TVF CGQ 12.3077
171 4CSV STI 12.3636
172 5ANU 58T 12.6582
173 2DXU BT5 12.766
174 2Z6C FMN 13.1783
175 1IS3 LAT 13.3333
176 1LNM DTX 13.587
177 3WG3 A2G GAL NAG FUC 14.6067
178 2AG4 OLA 15.2439
179 2II3 CAO 15.2672
180 1SU2 ATP 16.3522
181 3T50 FMN 20.3125
182 2AZ5 307 31.7568
183 2GU8 796 40
Pocket No.: 4; Query (leader) PDB : 5LUN; Ligand: ARG; Similar sites found with APoc: 194
This union binding pocket(no: 4) in the query (biounit: 5lun.bio2) has 27 residues
No: Leader PDB Ligand Sequence Similarity
1 6B79 ORA None
2 5BQS 4VN 1.85759
3 6EOZ AKG 1.94805
4 6EOZ 58K 1.94805
5 4Y3O OGA 1.98864
6 4CCK OGA 1.98864
7 4CCO OGA 1.98864
8 6EXF LYS 1.98864
9 5FWJ MMK 1.98864
10 1OFL NGK GCD 1.98864
11 5A3T MMK 1.98864
12 2EAE FUL 1.98864
13 2PNC CLU 1.98864
14 4Y9T PA1 2.02312
15 1LSH PLD 2.19436
16 2JIG PD2 2.23214
17 2A1X AKG 2.27273
18 1KTC NGA 2.27273
19 1F9V ADP 2.30548
20 1KGI T4A 2.3622
21 1VC9 ATP 2.38095
22 3ZJX BOG 2.42215
23 3SAO DBH 2.5
24 3SAO NKN 2.5
25 2HK9 SKM 2.54545
26 5NCJ HL5 2.61194
27 5NCJ SIN 2.61194
28 5EQU AKG 2.62295
29 5EXK 5AD 2.71903
30 1OS7 AKG 2.82686
31 1OS7 TAU 2.82686
32 3TDC 0EU 2.84091
33 2GVJ DGB 2.84091
34 1QY1 PRZ 2.87356
35 5I0U DCY 3
36 1UYY BGC BGC 3.05344
37 4NAO AKG 3.06748
38 2OG7 SIN 3.125
39 5JWP AKG 3.125
40 2Y0I AKG 3.125
41 5X7Q GLC GLC GLC GLC GLC 3.125
42 4BG1 IVL 3.125
43 4BG1 OGA 3.125
44 2QPU QPU 3.125
45 2XUM OGA 3.15186
46 3P3N AKG 3.15186
47 4B7E OGA 3.15186
48 2WA4 069 3.15186
49 1J3R 6PG 3.15789
50 2ZMF CMP 3.1746
51 2GC0 PAN 3.19149
52 5HV0 AKG 3.22581
53 3T0W DIW 3.25203
54 5LXB 7A9 3.30579
55 5EW9 5VC 3.32103
56 5LY1 PPI 3.40909
57 5LY2 OGA 3.40909
58 5FWE OGA 3.40909
59 6H8P OGA 3.40909
60 5A0U CHT 3.40909
61 4ZXA H8N 3.57143
62 5W10 CMP 3.58974
63 4OCT AKG 3.6036
64 6FXR AKG 3.69318
65 4RF7 ARG 3.69318
66 4WOE ADP 3.69318
67 1YFS ALA 3.69318
68 3A16 PXO 3.69318
69 3JQ3 ADP 3.69318
70 2IUW AKG 3.78151
71 1OGX EQU 3.81679
72 5YBL AKG 3.82166
73 3NZ1 3NY 3.83142
74 4RFR RHN 3.94089
75 5OX6 A1Z 3.96825
76 5L6G XYP 3.97727
77 2WBP SIN 3.97727
78 2WBP ZZU 3.97727
79 2ET1 GLV 3.9801
80 5TFZ 7BC 4
81 1DRY AAG 4.01235
82 1DRY AKG 4.01235
83 1Q6I FK5 4.01786
84 3SCH TB6 4.0404
85 3HQR OGA 4.06504
86 3MPB FRU 4.06504
87 1ELI PYC 4.26136
88 4IE6 UN9 4.26136
89 4UF0 MMK 4.26136
90 2J5B TYE 4.31034
91 4M26 AKG 4.3956
92 4M26 SIN 4.3956
93 4M26 ZZU 4.3956
94 1DMY AZM 4.43548
95 6GNO XDI 4.44444
96 1N5S ADL 4.46429
97 2FCU AKG 4.47284
98 6F6D AKG 4.54545
99 5HV7 RBL 4.54545
100 1YKD CMP 4.54545
101 4MPO AMP 4.57516
102 4JZR 4JR 4.62963
103 6F4T OGA 4.70588
104 5VNF VAL THR SER VAL VAL 4.82955
105 1LRH NLA 4.90798
106 5LX9 OLB 4.92958
107 5WL1 D3D 5.05051
108 5WL1 CUY 5.05051
109 6EWZ APC 5.06329
110 1DZK PRZ 5.09554
111 6FOF LAT 5.10204
112 1U8X G6P 5.11364
113 3ITA AIC 5.11364
114 1VRP ADP 5.11364
115 5ZM4 9FU 5.22876
116 5ZM4 AKG 5.22876
117 4XCB AKG 5.36398
118 4XCB HY0 5.36398
119 2VL1 GLY GLY 5.39773
120 3PUR 2HG 5.39773
121 3N9P OGA 5.39773
122 3N9Q OGA 5.39773
123 3N9O OGA 5.39773
124 5Y4K AKR 5.39773
125 4L4J NAG NAG BMA MAN NAG 5.42986
126 1NX4 AKG 5.49451
127 6D61 4AA 5.64103
128 5KJW 53C 5.68182
129 3KV4 OGA 5.68182
130 3N29 NSD 5.68182
131 3WW2 LPK 5.85938
132 3WW2 SF6 5.85938
133 1ZZ7 S0H 6.06061
134 5HWV MBN 6.15385
135 1FHX 4IP 6.20155
136 4LIT AKG 6.25
137 2NZ2 CIR 6.25
138 4HSJ 6PC 6.32184
139 5AIG VPR 6.4
140 4UEC MGT 6.52174
141 4BXF AKG 6.53409
142 5L2R MLA 6.81818
143 4IU6 FZ1 6.81818
144 5OCG 9R5 6.87831
145 4MOB ADP 6.92771
146 4QM9 CYS 6.93642
147 5JSP DQY 6.96517
148 1UNB AKG 7.07396
149 1UNB PN1 7.07396
150 3AVR OGA 7.10227
151 2RDQ AKG 7.29167
152 4OJ8 AKG 7.50853
153 4OJ8 2TQ 7.50853
154 6FA4 D1W 7.51445
155 1GT4 UNA 7.54717
156 5FUI APY 7.57576
157 4NPL AKG 7.6
158 1QKQ MAN 7.74648
159 4JLS 3ZE 7.89474
160 5NW7 9C2 7.95455
161 4FFG 0U8 7.95455
162 6F6J CUW 8.37989
163 6F6J SIN 8.37989
164 1OIJ AKG 8.9701
165 1OIK AKG 8.9701
166 1OIK C26 8.9701
167 1Y9Q MED 9.375
168 5W71 PLP 9.375
169 5C1M OLC 9.6
170 5C5T AKG 10.0877
171 4ZU4 4TG 10.1351
172 1KTG AMP 10.1449
173 5TZO 7V7 10.6383
174 5VKM GAL SIA 10.7955
175 5Y02 HBX 11.215
176 4P7X AKG 11.6438
177 4P7X YCP 11.6438
178 4YEE 4CQ 12.2222
179 3A76 SPD 12.5
180 5XEG AKG 12.5541
181 4RLT FSE 13.6054
182 4G7A AZM 15.3226
183 1GP6 QUE 16.1932
184 1GP6 SIN 16.1932
185 1GP6 DH2 16.1932
186 5ABX MGP 19.5122
187 1H2M OGA 21.1538
188 4QXB OGA 23.5294
189 5O9W AKG 24.7159
190 1ODM ASV 25.6798
191 4CCN OGA 25.7143
192 1H2K OGA 26.8293
193 5C3R AKG 34.1108
194 5C3R HMU 34.1108
Pocket No.: 5; Query (leader) PDB : 5LUN; Ligand: ARG; Similar sites found with APoc: 8
This union binding pocket(no: 5) in the query (biounit: 5lun.bio4) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 3NYQ MCA 1.70455
2 4IVG ANP 1.70455
3 3OV6 MK0 1.70455
4 4W6Z ETF 1.72911
5 1JQ3 AAT 2.36486
6 2R40 20E 3.04183
7 3OVR 5SP 3.50877
8 4LIX AG8 6.53409
Pocket No.: 6; Query (leader) PDB : 5LUN; Ligand: OGA; Similar sites found with APoc: 33
This union binding pocket(no: 6) in the query (biounit: 5lun.bio4) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 4OAS 2SW None
2 5DX9 T6P 1.58228
3 4IJP 1EH 1.70455
4 3H78 BE2 1.70455
5 1YIQ PQQ 2.27273
6 2IXC TRH 2.47525
7 6BFN DL1 2.63158
8 3N0Y APC 2.7933
9 5BNS 4VM 2.83912
10 3TYZ PAB 2.85714
11 5DXI TRE 2.98013
12 6H8P OGA 3.40909
13 1OI6 TMP 3.41463
14 4JH6 FCN 3.62319
15 1PZL MYR 3.79747
16 1OGX EQU 3.81679
17 1QIN GIP 3.82514
18 3PQB VGP 3.97727
19 2P8B NSK 3.97727
20 1ULE GLA GAL NAG 4
21 4GGZ BTN 4.34783
22 4Y24 TD2 4.54545
23 2C1Q BTN 4.7619
24 3L5R 47X 4.91803
25 4WVO 3UZ 5.13595
26 1IGJ DGX 5.9633
27 3WDX BGC BGC GLC 6.37584
28 2WQP WQP 6.59026
29 4QCK ASD 7.10227
30 5MBC FMN 7.38636
31 1R5L VIV 7.63359
32 5BVE 4VG 8.23864
33 5Y02 HBX 11.215
Pocket No.: 7; Query (leader) PDB : 5LUN; Ligand: OGA; Similar sites found with APoc: 63
This union binding pocket(no: 7) in the query (biounit: 5lun.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 1HBK COA None
3 3T5M AMP 2.08333
4 5EY0 GTP 2.18978
5 1M2Z BOG 2.33463
6 1VC9 ATP 2.38095
7 3G3N TC8 2.51572
8 6CB2 OLC 2.73038
9 3TDC 0EU 2.84091
10 2OZ5 7XY 3.04054
11 2AOT 2PM 3.08219
12 3OPT AKG 3.125
13 3T0W DIW 3.25203
14 2WMC MGP 3.37079
15 4PSR FUL 3.40909
16 4RD0 GDP 3.40909
17 6D50 GCB 3.40909
18 2HXT EHM 3.69318
19 6GSG RCO 3.97727
20 5L6G XYP 3.97727
21 3MPB FRU 4.06504
22 2WDA L42 4.26136
23 2J5B TYE 4.31034
24 1X8X TYR 4.34783
25 5DG2 GAL GLC 4.44444
26 5HV7 RBL 4.54545
27 4MRP GSH 4.56026
28 4DE3 DN8 4.56274
29 2YMZ LAT 4.61538
30 5LX9 OLB 4.92958
31 6FOF LAT 5.10204
32 1NU4 MLA 5.15464
33 2BHW NEX 5.17241
34 3WW2 SF6 5.85938
35 1DTL BEP 6.21118
36 2NZ2 CIR 6.25
37 2V95 HCY 6.25
38 4HSJ 6PC 6.32184
39 5GM5 CBI 6.36364
40 5AIG VPR 6.4
41 1JW0 GUA 6.96203
42 3WUD GLC GAL 7.35294
43 1TV5 N8E 7.38636
44 1LNX URI 7.40741
45 2PRG BRL 7.95455
46 3MYZ TFX 8
47 5CHR 4NC 8.0292
48 1TW4 CHD 8.8
49 3DOO SKM 9.02527
50 1Y9Q MED 9.375
51 5C1M OLC 9.6
52 5C1M 4VO 9.6
53 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 9.62343
54 2VDY HCY 10.2273
55 6CGN DA 10.7955
56 1ZDQ MSM 11.0119
57 5Y02 MXN 11.215
58 4YEE 4CQ 12.2222
59 2Y69 CHD 17.1429
60 1A78 TDG 20.8955
61 5W97 CHD 26.087
62 5ZCO CHD 26.087
63 4OGQ 2WD 27.5862
Pocket No.: 8; Query (leader) PDB : 5LUN; Ligand: ARG; Similar sites found with APoc: 56
This union binding pocket(no: 8) in the query (biounit: 5lun.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 1HBK COA None
3 3T5M AMP 2.08333
4 5EY0 GTP 2.18978
5 4USF 6UI 2.30263
6 1M2Z BOG 2.33463
7 3G3N TC8 2.51572
8 6CB2 OLC 2.73038
9 1U6R ADP 2.84091
10 2OZ5 7XY 3.04054
11 2AOT 2PM 3.08219
12 3T03 3T0 3.16901
13 2WMC MGP 3.37079
14 4PSR FUL 3.40909
15 4RD0 GDP 3.40909
16 6D50 GCB 3.40909
17 4JH6 FCN 3.62319
18 2HXT EHM 3.69318
19 6GSG RCO 3.97727
20 2WDA L42 4.26136
21 1X8X TYR 4.34783
22 5DG2 GAL GLC 4.44444
23 4MRP GSH 4.56026
24 4DE3 DN8 4.56274
25 2YMZ LAT 4.61538
26 2XMY CDK 5.03356
27 1NU4 MLA 5.15464
28 2BHW NEX 5.17241
29 3CBC DBS 6.06061
30 1DTL BEP 6.21118
31 2V95 HCY 6.25
32 5GM5 CBI 6.36364
33 4KBA 1QM 6.53409
34 3WUD GLC GAL 7.35294
35 1TV5 N8E 7.38636
36 1LNX URI 7.40741
37 2PRG BRL 7.95455
38 3MYZ TFX 8
39 5CHR 4NC 8.0292
40 1TW4 CHD 8.8
41 3DOO SKM 9.02527
42 5C1M 4VO 9.6
43 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 9.62343
44 2VDY HCY 10.2273
45 6CGN DA 10.7955
46 5Y02 MXN 11.215
47 3PDT ADP 11.2727
48 5TVF CGQ 12.3077
49 1IS3 LAT 13.3333
50 1LNM DTX 13.587
51 2Y69 CHD 17.1429
52 1A78 TDG 20.8955
53 5FLJ QUE 21.5054
54 5W97 CHD 26.087
55 5ZCO CHD 26.087
56 4OGQ 2WD 27.5862
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