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Receptor
PDB id Resolution Class Description Source Keywords
5MGZ 1.9 Å EC: 2.1.1.284 STREPTOMYCES SPHEROIDES NOVO (8-DEMETHYLNOVBIOCIC ACID METHYLTRANSFERASE) WITH SAH STREPTOMYCES NIVEUS C METHYLTRANSFERASE NOVOBIOCIN BIOSYNTHESIS SAM DEPENDENTTRANSFERASE
Ref.: STRUCTURAL AND FUNCTIONAL BASIS OF C-METHYLATION OF SCAFFOLDS BY NOVO. ACS CHEM. BIOL. V. 12 374 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT A:303;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
SAH A:301;
B:301;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
GOL A:302;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5MGZ 1.9 Å EC: 2.1.1.284 STREPTOMYCES SPHEROIDES NOVO (8-DEMETHYLNOVBIOCIC ACID METHYLTRANSFERASE) WITH SAH STREPTOMYCES NIVEUS C METHYLTRANSFERASE NOVOBIOCIN BIOSYNTHESIS SAM DEPENDENTTRANSFERASE
Ref.: STRUCTURAL AND FUNCTIONAL BASIS OF C-METHYLATION OF SCAFFOLDS BY NOVO. ACS CHEM. BIOL. V. 12 374 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5MGZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 54 families.
1 5MGZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5M58 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 47 families.
1 5MGZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5M58 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5MGZ; Ligand: SAH; Similar sites found with APoc: 731
This union binding pocket(no: 1) in the query (biounit: 5mgz.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 5O0Z 9GB None
2 1ONI BEZ None
3 2PXX SAH 0.930233
4 5MPT SAH 1.27119
5 1G55 SAH 1.27119
6 1L5Y BEF 1.27119
7 4XUC SAM 1.37615
8 4XUC 43G 1.37615
9 2YY7 NAD 1.69492
10 1RP0 AHZ 1.69492
11 2WPB ZZI 1.69492
12 3D3W NAP 1.69492
13 1U1I NAD 1.69492
14 1M2K APR 1.69492
15 1PR9 NAP 1.69492
16 6C8R SAH 2.11864
17 1ORR NAD 2.11864
18 6C8R EQV 2.11864
19 6DEN TP9 2.11864
20 6DEN G8A 2.11864
21 6DEN FAD 2.11864
22 5ZYN FAD 2.11864
23 3CH6 NAP 2.11864
24 3CH6 311 2.11864
25 4D7E FAD 2.11864
26 4YNU LGC 2.11864
27 4YNU FAD 2.11864
28 2NYA MGD 2.11864
29 1RKX NAD 2.11864
30 3UCL CYH 2.11864
31 3UCL FAD 2.11864
32 3UCL NAP 2.11864
33 1AE1 NAP 2.11864
34 3HVJ 705 2.26244
35 2CHT TSA 2.3622
36 3VSE SAH 2.54237
37 4KGD FAD 2.54237
38 4KGD TDP 2.54237
39 1SB8 UD2 2.54237
40 1SB8 NAD 2.54237
41 4RPL FAD 2.54237
42 4RPL 3UC 2.54237
43 5FWA J7C 2.54237
44 4RDH AMP 2.54237
45 2Z3Y F2N 2.54237
46 4RDI ATP 2.54237
47 1XSE NDP 2.54237
48 1TL2 NDG 2.54237
49 1DMR PGD 2.54237
50 1EU1 MGD 2.54237
51 4FC7 NAP 2.54237
52 4FC7 COA 2.54237
53 4XQC NAD 2.54237
54 4XQC 13D 2.54237
55 1WVG APR 2.54237
56 2C7G ODP 2.54237
57 2C7G FAD 2.54237
58 1Q1R FAD 2.54237
59 5Y2W PGA 2.5641
60 3CBG SAH 2.58621
61 2ZFU SAH 2.7907
62 3G2O SAM 2.9661
63 2YX1 SFG 2.9661
64 2EJU SAH 2.9661
65 3ELW SAM 2.9661
66 3ELW GP3 2.9661
67 3EVG SAH 2.9661
68 2DPM SAM 2.9661
69 3EVF SAH 2.9661
70 3EVF GTA 2.9661
71 3LKZ SFG 2.9661
72 4YAC NAI 2.9661
73 5ULP KB1 2.9661
74 4LHD GLY 2.9661
75 4Y9D NAI 2.9661
76 6FDF SAH 2.9661
77 5BVA FAD 2.9661
78 3GRU AMP 2.9661
79 2I7C AAT 2.9661
80 2E5V FAD 2.9661
81 4OPC FDA 2.9661
82 4OPC PGT 2.9661
83 2PX8 SAH 2.9661
84 5HSA FAS 2.9661
85 3ML1 MGD 2.9661
86 2Q7V FAD 2.9661
87 1EDO NAP 2.9661
88 4D79 ATP 2.9661
89 3HDY FDA 2.9661
90 3HDY GDU 2.9661
91 3VYW SAM 2.9661
92 3LU1 NAD 2.9661
93 5KMS NAD 2.9661
94 4GLL NAD 2.9661
95 3WDM ADN 2.9661
96 3LXD FAD 2.9661
97 5EZ7 FAD 2.9661
98 3HDY FAD 2.9661
99 2QA1 FAD 2.9661
100 5XNC MTA 3.2345
101 2VT3 ATP 3.25581
102 6ECU SAH 3.38983
103 5E9W SAH 3.38983
104 5E8J SAH 3.38983
105 5FTW SAH 3.38983
106 3NDJ SAH 3.38983
107 3NDJ JHZ 3.38983
108 4C4A SAH 3.38983
109 4BLW AMP 3.38983
110 3FUU ADN 3.38983
111 5BJX NAD 3.38983
112 5BJX UDP 3.38983
113 4N49 SAM 3.38983
114 2PT9 2MH 3.38983
115 1DL5 SAH 3.38983
116 6B3A SAM 3.38983
117 2JB2 FAD 3.38983
118 2JB2 PHE 3.38983
119 3U4C NDP 3.38983
120 3S1S SAH 3.38983
121 1I8T FAD 3.38983
122 1RSG FAD 3.38983
123 1YQZ FAD 3.38983
124 1H82 GZZ 3.38983
125 1QO8 FAD 3.38983
126 2IV2 MGD 3.38983
127 1H82 FAD 3.38983
128 3GD4 FAD 3.38983
129 1YY5 FAD 3.38983
130 1BXK NAD 3.38983
131 3GD4 NAD 3.38983
132 3WMX NAD 3.38983
133 2Q28 ADP 3.38983
134 4BLW SAH 3.38983
135 5TS5 FAD 3.38983
136 1VR0 3SL 3.38983
137 3AB1 FAD 3.38983
138 5EJ2 NAD 3.38983
139 1PN0 IPH 3.38983
140 1FEC FAD 3.38983
141 1PN0 FAD 3.38983
142 2PT9 S4M 3.38983
143 2GDZ NAD 3.38983
144 4NTC FAD 3.38983
145 6B3V ANP 3.38983
146 6B3V 7DQ 3.38983
147 1GPE FAD 3.38983
148 1Z45 NAD 3.38983
149 1XG5 NAP 3.38983
150 4DSG UDP 3.38983
151 4DSG FAD 3.38983
152 4BV6 FAD 3.38983
153 1G0N NDP 3.38983
154 3DUW SAH 3.58744
155 5L95 AMP 3.75
156 2EG5 SAH 3.81356
157 6ECW SAH 3.81356
158 2OBF SAH 3.81356
159 2OBF F83 3.81356
160 3GCZ SAM 3.81356
161 1JQ3 AAT 3.81356
162 1V59 NAD 3.81356
163 2ZWA SAH 3.81356
164 5YJF 8WO 3.81356
165 5YJI 8WO 3.81356
166 5YJI SAH 3.81356
167 4YAG NAI 3.81356
168 1I9G SAM 3.81356
169 5YJF SAH 3.81356
170 1GY8 NAD 3.81356
171 1IY8 NAD 3.81356
172 4WXJ GLU 3.81356
173 6F3M NAD 3.81356
174 6F3N NAD 3.81356
175 6F3N ADN 3.81356
176 1KEW NAD 3.81356
177 1Y8Q ATP 3.81356
178 4K26 SFF 3.81356
179 4K26 NDP 3.81356
180 3KLJ FAD 3.81356
181 4D04 FAD 3.81356
182 4D04 NAP 3.81356
183 1V59 FAD 3.81356
184 1BZL FAD 3.81356
185 4II2 ATP 3.81356
186 5TTJ FAD 3.81356
187 3LZW NAP 3.81356
188 1E6W NAD 3.81356
189 3LZW FAD 3.81356
190 6F9Q NAD 3.81356
191 1VL8 NAP 3.81356
192 5U8U FAD 3.81356
193 4REP FAD 3.81356
194 1E3W NAD 3.81356
195 6ER9 FAD 3.81356
196 6ER9 NAP 3.81356
197 6GAS FAD 3.81356
198 3GDN HBX 3.81356
199 3GDN FAD 3.81356
200 2IZ1 ATR 3.81356
201 2WET FAD 3.81356
202 3QPB URA 3.81356
203 5BRT FAD 3.81356
204 5BRT CH9 3.81356
205 5OC1 FAD 3.81356
206 5DF1 NAP 3.81356
207 5DF1 58X 3.81356
208 1EK6 NAI 3.81356
209 1EK6 UPG 3.81356
210 6CI9 NAP 3.81356
211 4B63 ORN 3.81356
212 4B63 FAD 3.81356
213 4B63 NAP 3.81356
214 3EYA FAD 3.81356
215 1Q8V MAN MAN MAN 3.81356
216 6DNT NAD 3.81356
217 5OJI NAP 3.81356
218 5OJI ISN 3.81356
219 1Q8P MAN MMA 3.81356
220 5JWC FAD 3.81356
221 1DCP HBI 3.84615
222 2CUL FAD 3.87931
223 5ZW3 SAH 4
224 2GN4 NDP 4.06977
225 2GN4 UD1 4.06977
226 6ARJ SAH 4.23729
227 6ARJ BW4 4.23729
228 1YBH FAD 4.23729
229 4YUW 4JU 4.23729
230 5DX8 SFG 4.23729
231 5DXA SFG 4.23729
232 2WA2 SAM 4.23729
233 5DX1 SFG 4.23729
234 5DX0 SFG 4.23729
235 5DWQ SFG 4.23729
236 4YUW S4M 4.23729
237 4ZRN NAD 4.23729
238 4ZRN UPG 4.23729
239 4UCI SAM 4.23729
240 5UFN SAH 4.23729
241 1O97 AMP 4.23729
242 1T9D P25 4.23729
243 1ZK7 FAD 4.23729
244 1T9D PYD 4.23729
245 1T9D 1MM 4.23729
246 5WKC FAD 4.23729
247 5N0J FAD 4.23729
248 1O97 FAD 4.23729
249 5M67 NAD 4.23729
250 5M67 3D1 4.23729
251 5M67 ADE 4.23729
252 1U7T TDT 4.23729
253 1T9D FAD 4.23729
254 3GF4 FAD 4.23729
255 2ZJ1 NAD 4.23729
256 5MBX SP5 4.23729
257 5MBX FAD 4.23729
258 2ZJ1 ARJ 4.23729
259 1RM0 NAI 4.23729
260 1RM0 D6P 4.23729
261 5EB4 FAD 4.23729
262 1XHC FAD 4.23729
263 2V3V MGD 4.23729
264 4CNK FAD 4.23729
265 4MCC 21X 4.23729
266 3GF4 UPG 4.23729
267 2Q46 NAP 4.23729
268 3U31 NAD 4.23729
269 5VN0 FAD 4.23729
270 2NVK FAD 4.23729
271 5VN0 NAI 4.23729
272 1KYQ NAD 4.23729
273 1VHW ADN 4.23729
274 6BQ6 TER 4.23729
275 4NBW NAD 4.23729
276 4RL4 PPV 4.24528
277 4IF4 BEF 4.32692
278 2VPY MGD 4.34783
279 5JCM ISD 4.43459
280 5JCM FAD 4.43459
281 5JCM NAD 4.43459
282 3I53 SAH 4.51807
283 2EFJ SAH 4.66102
284 3GWZ SAH 4.66102
285 5YF1 SFG 4.66102
286 3GXO SAH 4.66102
287 2A14 SAH 4.66102
288 1UAY ADN 4.66102
289 5FUB SAH 4.66102
290 5YF1 8V0 4.66102
291 3DMH SAM 4.66102
292 1WG8 SAM 4.66102
293 1YXM ADE 4.66102
294 5W7R SAH 4.66102
295 5W7R 9Z7 4.66102
296 1NJR XYL 4.66102
297 5FJN BE2 4.66102
298 5FJN FAD 4.66102
299 1X87 NAD 4.66102
300 3DMH GMP 4.66102
301 3OND NAD 4.66102
302 3OND ADN 4.66102
303 1ZEM NAD 4.66102
304 1XKQ NDP 4.66102
305 2WSB NAD 4.66102
306 5NMX FAD 4.66102
307 6H3O FAD 4.66102
308 1PJS NAD 4.66102
309 2CDU FAD 4.66102
310 5NMX NAP 4.66102
311 3CTY FAD 4.66102
312 1ZBQ NAD 4.66102
313 2DKH FAD 4.66102
314 2DKH 3HB 4.66102
315 2CDU ADP 4.66102
316 5MLR GRQ 4.66102
317 5MLR NAP 4.66102
318 2XYQ SAH 4.66102
319 2ZXI FAD 4.66102
320 4J36 FAD 4.66102
321 4J36 1HR 4.66102
322 2ZWI C5P 4.66102
323 1FUT 2GP 4.71698
324 2HK9 ATR 4.72727
325 4JCA CIT 4.79042
326 1MUU NAD 4.81651
327 3FPZ AHZ 4.90798
328 4POO SAM 5
329 5HJM MTA 5.08475
330 4Y30 49L 5.08475
331 4RVG TYD 5.08475
332 4RVG SAM 5.08475
333 3PT9 SAH 5.08475
334 3A4T SFG 5.08475
335 6BWL NAD 5.08475
336 2IVF MGD 5.08475
337 4JNA FAD 5.08475
338 2HQM FAD 5.08475
339 4MIG G3F 5.08475
340 4HXY NDP 5.08475
341 3RKR NAP 5.08475
342 3ZNN 4WL 5.08475
343 3ZNN FAD 5.08475
344 4Z24 FAD 5.08475
345 4Y30 SAH 5.08475
346 3ICT FAD 5.08475
347 1LVL NAD 5.08475
348 1LVL FAD 5.08475
349 2BD0 NAP 5.32787
350 3LCV SAM 5.50847
351 4DMG SAM 5.50847
352 3A27 SAM 5.50847
353 1U2Z SAH 5.50847
354 1NW5 SAM 5.50847
355 4RSL FAD 5.50847
356 3ZV6 4HB 5.50847
357 3ZV6 NAD 5.50847
358 2Q1W NAD 5.50847
359 5TWB FAD 5.50847
360 4EUE NAI 5.50847
361 5O4J SAH 5.50847
362 4MO2 FDA 5.50847
363 4MO2 FAD 5.50847
364 5O4J 9KH 5.50847
365 5O4J PJL 5.50847
366 4PIO AVI 5.50847
367 1XHL NDP 5.50847
368 1I2B UPG 5.50847
369 1I2B NAD 5.50847
370 1I2B USQ 5.50847
371 4PIO SAH 5.50847
372 3QJ4 FAD 5.50847
373 6EL3 NAP 5.50847
374 2R4J FAD 5.50847
375 2R4J 13P 5.50847
376 2V6G NAP 5.50847
377 5CGM MAL 5.50847
378 4X60 SFG 5.50847
379 2A8X FAD 5.50847
380 4X60 3XV 5.50847
381 1XCL SAH 5.53191
382 5J5Z FAD 5.64516
383 3O7W SAM 5.9322
384 4TQG NDP 5.9322
385 1ZGA SAH 5.9322
386 1EFV FAD 5.9322
387 1EFV AMP 5.9322
388 5O42 NAD 5.9322
389 5O42 BGC 5.9322
390 5O42 9JW 5.9322
391 1OC2 TDX 5.9322
392 1OC2 NAD 5.9322
393 2VVM FAD 5.9322
394 2VVL FAD 5.9322
395 5BUK FAD 5.9322
396 5F2K OCA 5.9322
397 5F2K SAH 5.9322
398 5WGR FAD 5.9322
399 1RLZ NAD 5.9322
400 4A34 FUL 6.12245
401 1XTP SAI 6.29921
402 1XDS SAM 6.35593
403 5ICE 2H4 6.35593
404 5ICE SAH 6.35593
405 3BGD SAH 6.35593
406 3A25 SAM 6.35593
407 1QAN SAH 6.35593
408 2P41 SAH 6.35593
409 3BGD PM6 6.35593
410 4FN4 NAD 6.35593
411 1V5F FAD 6.35593
412 1V5F TPP 6.35593
413 1ELI PYC 6.35593
414 5J60 FAD 6.35593
415 4AT0 FAD 6.35593
416 3E1T FAD 6.35593
417 4U8P UDP 6.35593
418 4U8P FDA 6.35593
419 3Q87 SAM 6.4
420 2BZG SAH 6.46552
421 5TVI O8N 6.52174
422 1P1C SAH 6.53266
423 5X62 SAH 6.77966
424 6D6Y SAH 6.77966
425 5T67 JHZ 6.77966
426 5T67 SAH 6.77966
427 6C5B SAH 6.77966
428 4D5G FAD 6.77966
429 4D5G TPP 6.77966
430 2EWM NAD 6.77966
431 4MOP 2H5 6.77966
432 5I39 FAD 6.77966
433 2C31 TZD 6.77966
434 2C31 ADP 6.77966
435 5MIT FAD 6.77966
436 5MIT NAP 6.77966
437 1RYI GOA 6.77966
438 5W3Y ACO 6.77966
439 1RYI FAD 6.77966
440 2UYQ SAM 6.77966
441 4CQM NAP 6.77966
442 3QWI NAP 6.77966
443 1SQL GUN 6.84932
444 1KQF MGD 6.91244
445 4QAR ADE 6.96517
446 3FRH SAH 7.20339
447 4ONQ SFG 7.20339
448 3P9C SAH 7.20339
449 5XLX SAH 7.20339
450 2YG3 FAD 7.20339
451 1REO FAD 7.20339
452 2XVE FAD 7.20339
453 4HA6 FAD 7.20339
454 3K7M FAD 7.20339
455 5D4V SAH 7.20339
456 5GZ9 MAN 7.20339
457 2XVF FAD 7.20339
458 4CPB GAL CN8 7.43802
459 1RJD SAM 7.62712
460 1BC5 SAH 7.62712
461 3SQP FAD 7.62712
462 1Q9I TEO 7.62712
463 1Q9I FAD 7.62712
464 2RAB NAD 7.62712
465 2FR1 NDP 7.62712
466 4DA6 GA2 7.62712
467 4E70 N7I 7.62712
468 2RAB FAD 7.62712
469 4AP3 FAD 7.62712
470 4AP3 NAP 7.62712
471 3IHG FAD 7.62712
472 1GPJ CIT 7.62712
473 2HMT NAI 7.63889
474 3K1X DBX 7.69231
475 3L9W AMP 7.74818
476 3L9W GSH 7.74818
477 2PWY SAH 7.75194
478 2FKA BEF 7.75194
479 1G8S MET 7.82609
480 1BDB NAD 7.94224
481 5N5D SAM 7.9646
482 2VDV SAM 8.05085
483 1FP2 SAH 8.05085
484 1FP2 HMO 8.05085
485 3O03 NAP 8.05085
486 6GAR FAD 8.05085
487 2WPF WPF 8.05085
488 3TKA SAM 8.05085
489 2WPF FAD 8.05085
490 2RH4 EMO 8.05085
491 2ZL4 ALA ALA ALA ALA 8.16327
492 5Z75 NAD 8.25688
493 1R6D NAD 8.30861
494 1R6D DAU 8.30861
495 3OFK SAH 8.33333
496 1KYZ SAH 8.47458
497 5XHA FRU 8.47458
498 4ITU NAI 8.47458
499 4ITU 1HS 8.47458
500 3ABI NAD 8.47458
501 3X0V FAD 8.47458
502 1KYZ FER 8.47458
503 3C6K SPD 8.66142
504 3C6K MTA 8.66142
505 3NYC IAR 8.66142
506 3NYC FAD 8.66142
507 5BSZ SAH 8.8983
508 1QZZ SAM 8.8983
509 3TKY SAH 8.8983
510 5K0A FAD 8.8983
511 2IID FAD 8.8983
512 2IID PHE 8.8983
513 5GWT SIN 8.8983
514 5GWT NAD 8.8983
515 5CUQ NSC 8.98876
516 3TLJ SAH 9.11528
517 1R18 SAH 9.2511
518 5JGL SAM 9.32203
519 1IM8 SAI 9.32203
520 2AOT SAH 9.32203
521 5BW4 SAM 9.32203
522 1SQF SAM 9.32203
523 4FZV SAM 9.32203
524 4LWP SAH 9.32203
525 1JQD SAH 9.32203
526 1JQD HSM 9.32203
527 1V8B NAD 9.32203
528 1JG3 ADN 9.3617
529 1N2X SAM 9.74576
530 6B92 SAH 9.74576
531 5ERG SAM 9.74576
532 6GFK SAH 9.74576
533 2RC8 DSN 9.74576
534 3VC1 GST 9.74576
535 3VC1 SAH 9.74576
536 5IL1 SAM 9.74576
537 3AYI HCI 9.74576
538 3AYI FAD 9.74576
539 5K7U SAM 9.74576
540 3P2E SAH 9.77778
541 4MA7 P2Z 9.85915
542 3GEG NAD 10.1695
543 5JJR SAH 10.1695
544 2JJQ SAH 10.1695
545 6F97 FAD 10.1695
546 5GT9 NAP 10.1695
547 1TZJ A3B 10.1695
548 4W6Z 8ID 10.1695
549 4NTD FAD 10.2941
550 5C2N NAG 10.4167
551 1FP1 SAH 10.5932
552 1G60 SAM 10.5932
553 2NXE SAM 10.5932
554 3PFG SAM 10.5932
555 3PFG TLO 10.5932
556 5DM1 SAH 10.5932
557 5DM1 5D7 10.5932
558 2RGO FAD 10.5932
559 1D4D FAD 10.5932
560 5FEU NAP 10.5932
561 5FFF 5XC 10.5932
562 5FFF NAP 10.5932
563 2IVD FAD 10.5932
564 2AE2 PTO 10.5932
565 2AE2 NAP 10.5932
566 2AG5 NAD 10.5932
567 3NUG NAD 10.5932
568 2JHP SAH 11.0169
569 4G5H UD7 11.0169
570 4G5H NAP 11.0169
571 3NJ4 AFX 11.0169
572 3NJ4 NAD 11.0169
573 4C3Y ANB 11.0169
574 4C3Y FAD 11.0169
575 4YDD MD1 11.0169
576 4YDD MGD 11.0169
577 3JWH SAH 11.0599
578 1WUW TSU 11.1111
579 3QFA FAD 11.2069
580 4M37 SAH 11.4407
581 6CZ7 MGD 11.4407
582 1NAA ABL 11.4407
583 1NAA 6FA 11.4407
584 3FGZ BEF 11.7188
585 4L2I FAD 11.7871
586 1F3L SAH 11.8644
587 5ME4 HP4 11.8644
588 3WGT FAD 11.8644
589 3WGT QSC 11.8644
590 2F5Z FAD 11.8644
591 3DXY SAM 11.9266
592 6GKV SAH 12.2881
593 3RNM FAD 12.2881
594 1R27 MGD 12.2881
595 3GMB FAD 12.2881
596 3OU2 SAH 12.3853
597 2ZIF SAM 12.7119
598 2BRY FAD 12.7119
599 4A59 AMP 12.7119
600 4TXI FAD 12.7119
601 4GKV NAD 12.7976
602 3FZG SAM 13
603 4KRG SAH 13.1356
604 5E72 SAM 13.1356
605 1UWK URO 13.1356
606 1UWK NAD 13.1356
607 4USQ FAD 13.1356
608 5KOK SAH 13.5593
609 5KOK S9T 13.5593
610 1COY FAD 13.5593
611 1COY AND 13.5593
612 5KOK R9T 13.5593
613 4YMH SAH 13.9831
614 5JAQ NAI 13.9831
615 5HXI 5HN 13.9831
616 5FA8 SAM 14.2857
617 3GDH SAH 14.4068
618 1UDB UFG 14.4068
619 1UDB NAD 14.4068
620 2O07 SPD 14.4068
621 2O07 MTA 14.4068
622 1OBB NAD 14.4068
623 5HJO XD3 14.4578
624 4URF NAD 14.5161
625 4KIB SAH 14.8305
626 5THY SAH 14.8305
627 3MB5 SAM 14.8305
628 5THZ SAH 14.8305
629 5E1M PRO PRO LYS ARG ILE ALA 14.8305
630 5E1M SAH 14.8305
631 4GUS FAD 14.8305
632 4HSU FAD 14.8305
633 4NBU NAI 14.8305
634 4GUT FAD 14.8305
635 4FWE FAD 14.8305
636 5EEH P9P 15.1596
637 5EEH SAH 15.1596
638 4M73 SAH 15.2542
639 4M73 M72 15.2542
640 3G89 SAM 15.678
641 1LSS NAD 15.7143
642 4J56 FAD 15.7895
643 1Q0S SAH 15.8301
644 3EGI ADP 16.0194
645 2PZM UDP 16.1017
646 2PZM NAD 16.1017
647 1NV8 MEQ 16.1017
648 1ZQ9 SAM 16.1017
649 1NV8 SAM 16.1017
650 1GZ6 NAI 16.1017
651 3AD8 PYC 16.1616
652 3AD8 FAD 16.1616
653 2GAG FAD 16.1616
654 2GAG FOA 16.1616
655 3AD8 NAD 16.1616
656 2GAG NAD 16.1616
657 5LOG SAH 16.309
658 3ZIA ADP 16.3934
659 4DCM SAM 16.5254
660 1S7G NAD 16.5254
661 1S7G APR 16.5254
662 2BGM NAJ 16.9065
663 3LCC SAH 16.9492
664 3LST SAH 16.9492
665 2DTX BMA 16.9492
666 3SSO SAH 16.9492
667 5DNK SAH 17.3729
668 3AXB PRO 17.7966
669 4EMI FAD 17.7966
670 4EMJ FAD 17.7966
671 3H8V ATP 17.8082
672 4GQB 0XU 18.1818
673 3GU3 SAH 18.2203
674 2FK8 SAM 18.2203
675 6DUB SAH 18.4685
676 6ECT SAM 18.6441
677 4A6D SAM 18.6441
678 2HNK SAH 18.6441
679 6F5Z SAH 19.0476
680 4M38 SAH 19.0476
681 1TPY SAH 19.0678
682 5U19 827 19.0678
683 5U19 SAH 19.0678
684 3S5W FAD 19.4915
685 4KRI SAH 19.9153
686 3EF0 ALF 19.9153
687 5FA5 MTA 20
688 5GWX SAR 20.339
689 5GWX SAM 20.339
690 1Z3C SA8 20.7627
691 1I1N SAH 20.7965
692 1VE3 SAM 21.1454
693 3FPF TNA 21.1864
694 3FPF MTA 21.1864
695 4OBW SAM 21.7899
696 4YSX FAD 21.8085
697 1L1E SAH 22.0339
698 3X0D SAH 22.0339
699 4QTU SAM 22.1154
700 3H2B SAH 22.6601
701 5YEC ATP 22.6891
702 1WY7 SAH 22.7053
703 5MW4 5JU 22.8814
704 3QOX SAH 22.8814
705 3T7S SAM 23.3051
706 3MQ2 SAH 23.3945
707 3BXO SAM 23.7288
708 5F8F SFG 24.1525
709 5DLY SAH 24.1525
710 5DLY 5D7 24.1525
711 4IWN GEK 24.4541
712 5W7K SAH 24.5763
713 4PNE SAH 24.5763
714 1G8K MGD 24.5763
715 1KPG SAH 25
716 5GM1 SAH 25.4237
717 4R6W PC 25.5814
718 4R6W SAH 25.5814
719 1KPH SAH 25.8475
720 4X9M FAD 25.8475
721 4NEC SAH 26.2712
722 2XVM SAH 26.6332
723 1E5Q NDP 26.6949
724 5WP5 SAH 27.1186
725 4AZW SAM 27.5424
726 1L3I SAH 27.6042
727 5W7M SAH 28.8136
728 5WP4 SAH 29.2373
729 1EJ0 SAM 30.5556
730 5JE0 AZ8 32.2034
731 5JE0 SAH 32.2034
Pocket No.: 2; Query (leader) PDB : 5MGZ; Ligand: SAH; Similar sites found with APoc: 21
This union binding pocket(no: 2) in the query (biounit: 5mgz.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 1LNX URI None
2 3A3B RBF 1.57895
3 2JK0 ASP 1.69492
4 1GEG NAD 2.9661
5 1A5V Y3 3.16456
6 2PHX MAN MAN MAN MAN 3.81356
7 1UKG MMA 3.81356
8 3CGB FAD 4.23729
9 5KVA SAM 4.31655
10 1BW9 NAD 4.66102
11 4RF7 ARG 4.66102
12 3W6X HZP 4.80349
13 2J5V RGP 5.08475
14 4M0R 644 6.77966
15 1NML CIT 6.77966
16 3A4V PYR 7.20339
17 3A4V NAD 7.20339
18 5UAO FAD 7.62712
19 1OCU PIB 8.02469
20 2FZW NAD 8.8983
21 5HXI FAD 13.9831
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