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Receptor
PDB id Resolution Class Description Source Keywords
5MW8 2.4 Å EC: 2.7.1.158 INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM M. MUSCUL COMPLEX WITH ATP AND IP5 MUS MUSCULUS PROTEIN STRUCTURE MAMMAL IPK INOSITOL KINASE TRANSFERASE
Ref.: THE CRYSTAL STRUCTURE OF MAMMALIAN INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE REVEALS A NEW ZINC-BINDING SITE AND KEY FEATURES FOR PROTEIN FUNC J. BIOL. CHEM. V. 292 10534 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:505;
A:504;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ACT A:506;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
ZN A:503;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
ATP A:501;
Valid;
none;
submit data
507.181 C10 H16 N5 O13 P3 c1nc(...
5MY A:502;
Valid;
none;
submit data
580.055 C6 H17 O21 P5 C1([C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5MW8 2.4 Å EC: 2.7.1.158 INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE FROM M. MUSCUL COMPLEX WITH ATP AND IP5 MUS MUSCULUS PROTEIN STRUCTURE MAMMAL IPK INOSITOL KINASE TRANSFERASE
Ref.: THE CRYSTAL STRUCTURE OF MAMMALIAN INOSITOL 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE REVEALS A NEW ZINC-BINDING SITE AND KEY FEATURES FOR PROTEIN FUNC J. BIOL. CHEM. V. 292 10534 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5MW8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5MW8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5MW8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ATP; Similar ligands found: 422
No: Ligand ECFP6 Tc MDL keys Tc
1 HEJ 1 1
2 ATP 1 1
3 5FA 0.985507 1
4 AQP 0.985507 1
5 AP5 0.927536 0.971831
6 B4P 0.927536 0.971831
7 BA3 0.913043 0.971831
8 ADP 0.9 1
9 A2D 0.884058 0.971831
10 AGS 0.84 0.945946
11 SAP 0.84 0.945946
12 6YZ 0.833333 0.972222
13 AT4 0.810811 0.958904
14 AN2 0.810811 0.985915
15 25L 0.809524 0.985915
16 AR6 0.802632 0.971831
17 APR 0.802632 0.971831
18 M33 0.8 0.958333
19 ACQ 0.794872 0.972222
20 TAT 0.794872 0.958904
21 T99 0.794872 0.958904
22 AD9 0.792208 0.972222
23 ACP 0.789474 0.972222
24 AMP 0.788732 0.971429
25 A 0.788732 0.971429
26 ANP 0.772152 0.972222
27 CA0 0.753247 0.945205
28 ADX 0.753247 0.873418
29 A22 0.746988 0.985915
30 50T 0.74359 0.958333
31 PRX 0.734177 0.893333
32 APC 0.734177 0.958904
33 ABM 0.733333 0.917808
34 ATF 0.731707 0.958904
35 ITT 0.730769 0.943662
36 7D4 0.730769 0.905405
37 ADQ 0.729412 0.945205
38 A3R 0.729412 0.907895
39 AP2 0.714286 0.958904
40 A12 0.714286 0.958904
41 A1R 0.709302 0.907895
42 SRA 0.706667 0.918919
43 5AL 0.698795 0.931507
44 HFD 0.695122 0.945946
45 9X8 0.693182 0.92
46 OAD 0.693182 0.945205
47 AU1 0.6875 0.972222
48 SRP 0.682353 0.906667
49 G5P 0.680851 0.921053
50 25A 0.678161 0.971831
51 3OD 0.677778 0.945205
52 4AD 0.670455 0.92
53 G3A 0.670213 0.921053
54 00A 0.662921 0.883117
55 RBY 0.662651 0.932432
56 ADP PO3 0.662651 0.943662
57 ADV 0.662651 0.932432
58 BIS 0.659341 0.933333
59 8QN 0.659091 0.931507
60 5SV 0.659091 0.848101
61 OOB 0.659091 0.931507
62 GTA 0.65625 0.886076
63 UP5 0.653061 0.92
64 AMO 0.651685 0.932432
65 PAJ 0.651685 0.884615
66 2A5 0.650602 0.918919
67 MAP 0.647727 0.945946
68 3AT 0.647059 0.971831
69 AHX 0.644444 0.896104
70 DLL 0.644444 0.931507
71 ATR 0.642857 0.971429
72 PAP 0.642857 0.985714
73 PTJ 0.641304 0.896104
74 7D3 0.6375 0.905405
75 3UK 0.637363 0.918919
76 SON 0.634146 0.932432
77 A4P 0.633663 0.843373
78 ALF ADP 0.632184 0.87013
79 ADP ALF 0.632184 0.87013
80 PR8 0.630435 0.85
81 WAQ 0.630435 0.883117
82 LAD 0.630435 0.860759
83 B5V 0.630435 0.906667
84 AFH 0.628866 0.884615
85 LMS 0.628205 0.82716
86 GAP 0.627907 0.893333
87 DTP 0.627907 0.905405
88 VO4 ADP 0.625 0.931507
89 ADP VO4 0.625 0.931507
90 TXA 0.623656 0.932432
91 ME8 0.623656 0.839506
92 1ZZ 0.623656 0.839506
93 NB8 0.623656 0.896104
94 FYA 0.623656 0.905405
95 DQV 0.622449 0.958333
96 T5A 0.621359 0.841463
97 ADN 0.619718 0.84507
98 RAB 0.619718 0.84507
99 XYA 0.619718 0.84507
100 DAL AMP 0.611111 0.905405
101 9SN 0.610526 0.871795
102 48N 0.61 0.896104
103 AP0 0.607843 0.896104
104 9ZD 0.604396 0.907895
105 9ZA 0.604396 0.907895
106 FA5 0.604167 0.906667
107 B5M 0.604167 0.894737
108 YAP 0.604167 0.894737
109 B5Y 0.604167 0.894737
110 NAI 0.60396 0.907895
111 6V0 0.60396 0.896104
112 TXD 0.60396 0.907895
113 DND 0.60396 0.932432
114 NXX 0.60396 0.932432
115 NAX 0.60396 0.873418
116 ADP BMA 0.602151 0.918919
117 A2R 0.6 0.985915
118 OMR 0.598039 0.851852
119 TXE 0.598039 0.907895
120 XAH 0.597938 0.839506
121 7DT 0.593023 0.985714
122 AOC 0.592593 0.821918
123 4UV 0.591837 0.894737
124 DDS 0.590909 0.878378
125 139 0.590476 0.873418
126 CNA 0.584906 0.932432
127 6AD 0.58427 0.909091
128 5AS 0.583333 0.77907
129 5N5 0.581081 0.819444
130 GA7 0.58 0.906667
131 4UU 0.58 0.894737
132 4TC 0.576923 0.896104
133 ADJ 0.575472 0.851852
134 5CD 0.573333 0.805556
135 A4D 0.573333 0.819444
136 RGT 0.571429 0.958904
137 A3P 0.571429 0.971429
138 7D5 0.56962 0.878378
139 LAQ 0.568627 0.839506
140 F2R 0.564815 0.864198
141 80F 0.563636 0.841463
142 YLP 0.563107 0.819277
143 A A 0.5625 0.944444
144 UPA 0.561905 0.907895
145 AV2 0.56044 0.917808
146 COD 0.559633 0.811765
147 4UW 0.557692 0.860759
148 JB6 0.556701 0.883117
149 3AM 0.555556 0.929577
150 ATP A A A 0.555556 0.930556
151 A2P 0.552941 0.957143
152 TYM 0.552381 0.906667
153 NA7 0.552083 0.958904
154 EP4 0.551282 0.753247
155 MYR AMP 0.55102 0.817073
156 PPS 0.549451 0.873418
157 YLC 0.54717 0.839506
158 YLB 0.54717 0.819277
159 NAD 0.545455 0.931507
160 DAT 0.545455 0.905405
161 TYR AMP 0.544554 0.87013
162 G5A 0.544444 0.77907
163 M2T 0.544304 0.734177
164 DTA 0.544304 0.786667
165 3DH 0.54321 0.773333
166 128 0.542857 0.776471
167 AHZ 0.538462 0.817073
168 GTP 0.537634 0.92
169 SSA 0.537634 0.8
170 MTA 0.5375 0.773333
171 IOT 0.537037 0.831325
172 A3D 0.535714 0.918919
173 ARG AMP 0.533981 0.829268
174 7MD 0.533981 0.8625
175 AR6 AR6 0.533981 0.917808
176 YLA 0.53211 0.819277
177 AMP DBH 0.529412 0.893333
178 IMO 0.529412 0.929577
179 TAD 0.528846 0.884615
180 AYB 0.527273 0.809524
181 A5A 0.526882 0.807229
182 HDV 0.526882 0.893333
183 TSB 0.526316 0.819277
184 EAD 0.525424 0.873418
185 2AM 0.52439 0.943662
186 6RE 0.52381 0.759494
187 7DD 0.522727 0.985714
188 V3L 0.521739 0.971831
189 AVV 0.520833 0.896104
190 BTX 0.517857 0.841463
191 NAE 0.517241 0.894737
192 52H 0.515789 0.77907
193 54H 0.515789 0.788235
194 VMS 0.515789 0.788235
195 NSS 0.515464 0.8
196 BT5 0.513274 0.831325
197 NAQ 0.512821 0.871795
198 ZAS 0.511905 0.766234
199 J7C 0.511628 0.769231
200 A3N 0.511628 0.786667
201 5X8 0.511111 0.763158
202 53H 0.510417 0.77907
203 8X1 0.510417 0.752809
204 5CA 0.510417 0.8
205 NVA LMS 0.510204 0.752809
206 ARU 0.510204 0.860759
207 AF3 ADP 3PG 0.509259 0.8375
208 ZID 0.508475 0.918919
209 P1H 0.508197 0.851852
210 OVE 0.505882 0.905405
211 S4M 0.505747 0.666667
212 LEU LMS 0.50505 0.752809
213 LPA AMP 0.504673 0.817073
214 7MC 0.504587 0.841463
215 DZD 0.5 0.884615
216 FB0 0.5 0.804598
217 MAO 0.5 0.759036
218 DSZ 0.5 0.8
219 LSS 0.5 0.761364
220 DSH 0.5 0.725
221 P5A 0.5 0.744444
222 NDE 0.495935 0.932432
223 N0B 0.495798 0.819277
224 M24 0.495726 0.85
225 YLY 0.495726 0.809524
226 NJP 0.495575 0.945946
227 9K8 0.49505 0.714286
228 MGP 0.494737 0.884615
229 6C6 0.494624 0.881579
230 NAJ PZO 0.491379 0.848101
231 0WD 0.491228 0.921053
232 6G0 0.489583 0.884615
233 GJV 0.488636 0.75
234 6FA 0.488189 0.841463
235 5AD 0.486842 0.746479
236 KAA 0.485149 0.752809
237 GSU 0.485149 0.77907
238 71V 0.483146 0.907895
239 NEC 0.482759 0.746667
240 A3G 0.482759 0.8
241 ODP 0.482456 0.909091
242 FAS 0.48062 0.851852
243 FAD 0.48062 0.851852
244 7D7 0.480519 0.743243
245 FDA 0.480315 0.833333
246 N6P 0.48 0.915493
247 2SA 0.479167 0.932432
248 GP3 0.478723 0.921053
249 4TA 0.478261 0.807229
250 SFG 0.478261 0.75
251 G A A A 0.478261 0.871795
252 AMP NAD 0.478261 0.905405
253 NPW 0.477876 0.886076
254 NDP 0.477876 0.921053
255 NDC 0.47619 0.871795
256 YSA 0.47619 0.77907
257 NAJ PYZ 0.475 0.807229
258 MGO 0.474227 0.860759
259 GDP 0.473684 0.92
260 NZQ 0.473684 0.909091
261 TXP 0.473684 0.921053
262 6IA 0.473684 0.8375
263 A7D 0.472527 0.776316
264 SFD 0.469231 0.734043
265 A5D 0.468085 0.786667
266 SA8 0.468085 0.707317
267 ZDA 0.468085 0.864865
268 12D 0.46789 0.785714
269 PGS 0.467391 0.883117
270 MHZ 0.467391 0.697674
271 8PZ 0.466667 0.8
272 62F 0.466165 0.8625
273 DA 0.465909 0.878378
274 D5M 0.465909 0.878378
275 GGZ 0.464646 0.825
276 SAH 0.463158 0.74359
277 SAI 0.463158 0.734177
278 FAY 0.462687 0.8625
279 Y3J 0.4625 0.726027
280 PO4 PO4 A A A A PO4 0.460784 0.902778
281 AAM 0.460674 0.971429
282 RFL 0.459259 0.821429
283 SMM 0.459184 0.686047
284 HF7 0.459184 0.893333
285 AMZ 0.458824 0.916667
286 C2R 0.458824 0.90411
287 SAM 0.458333 0.690476
288 A3S 0.456522 0.810811
289 FNK 0.455224 0.804598
290 U A 0.453782 0.907895
291 7C5 0.453704 0.818182
292 EEM 0.453608 0.690476
293 AAT 0.453608 0.707317
294 XNP 0.452991 0.873418
295 A G 0.452991 0.883117
296 PRT 0.45283 0.931507
297 AIR 0.451219 0.901408
298 62X 0.45098 0.666667
299 DCA 0.45 0.823529
300 ETB 0.45 0.833333
301 GSP 0.45 0.873418
302 U A G G 0.449153 0.883117
303 NIA 0.448276 0.822785
304 A3T 0.446809 0.821918
305 A A A 0.446602 0.905405
306 K15 0.446602 0.682353
307 PUA 0.446281 0.884615
308 6K6 0.445545 0.930556
309 GEK 0.445545 0.7375
310 4YB 0.445455 0.761364
311 S7M 0.444444 0.690476
312 Z5A 0.443548 0.77907
313 1DG 0.443548 0.921053
314 DG1 0.443548 0.921053
315 0T1 0.442623 0.823529
316 COA 0.442623 0.823529
317 WSA 0.442478 0.788235
318 8BR 0.43956 0.906667
319 8Q2 0.438596 0.772727
320 101 0.438202 0.878378
321 IDP 0.4375 0.918919
322 NVA 2AD 0.4375 0.759494
323 9JJ 0.435714 0.8625
324 NAP 0.435484 0.945205
325 APU 0.434783 0.894737
326 A U 0.434783 0.87013
327 7RP 0.433333 0.928571
328 A6D 0.432692 0.722892
329 AMX 0.432 0.833333
330 J7V 0.432 0.833333
331 TAP 0.432 0.907895
332 COS 0.432 0.804598
333 CAO 0.432 0.795455
334 30N 0.432 0.752688
335 V1N 0.431193 0.917808
336 649 0.429825 0.744444
337 P5F 0.429577 0.823529
338 NA0 0.428571 0.932432
339 SCO 0.428571 0.823529
340 CMX 0.428571 0.823529
341 7RA 0.428571 0.957747
342 0UM 0.427184 0.698795
343 GAV 0.427184 0.884615
344 QQY 0.426966 0.815789
345 1RB 0.426966 0.885714
346 ACK 0.426966 0.861111
347 G1R 0.425743 0.907895
348 GCP 0.425743 0.896104
349 FAM 0.425197 0.804598
350 FCX 0.425197 0.795455
351 ACO 0.425197 0.795455
352 GNH 0.424242 0.907895
353 F2N 0.423611 0.813953
354 GKE 0.422018 0.884615
355 GDD 0.422018 0.884615
356 GDC 0.422018 0.884615
357 HAX 0.421875 0.804598
358 3AD 0.421687 0.805556
359 9GM 0.421569 0.896104
360 GNP 0.421569 0.896104
361 FA9 0.42069 0.864198
362 TM1 0.420561 0.77381
363 KB1 0.420561 0.698795
364 H6Y 0.42 0.945205
365 2MC 0.419847 0.769231
366 3KK 0.418605 0.804598
367 FYN 0.418605 0.823529
368 S8M 0.417476 0.759494
369 7L1 0.417323 0.795455
370 2VA 0.416667 0.8
371 26A 0.416667 0.763158
372 NHD 0.416667 0.905405
373 QQX 0.41573 0.805195
374 CA6 0.415385 0.729167
375 OXK 0.415385 0.804598
376 COK 0.415385 0.804598
377 SOP 0.415385 0.804598
378 MCD 0.415385 0.804598
379 YE1 0.413534 0.813953
380 RMB 0.413043 0.873239
381 FAI 0.413043 0.916667
382 AS 0.413043 0.833333
383 CO6 0.412214 0.804598
384 1VU 0.412214 0.795455
385 CMC 0.412214 0.804598
386 NMX 0.412214 0.76087
387 SXZ 0.411215 0.710843
388 ANZ 0.410714 0.8
389 SCA 0.410448 0.804598
390 CAJ 0.409091 0.804598
391 SCD 0.409091 0.823529
392 EO7 0.408602 0.788235
393 D3Y 0.407767 0.789474
394 CC5 0.407407 0.816901
395 KH3 0.40708 0.674419
396 A C A C 0.406504 0.848101
397 SLU 0.406504 0.770115
398 G 0.40625 0.906667
399 5GP 0.40625 0.906667
400 A1S 0.406015 0.804598
401 IVC 0.406015 0.813953
402 MLC 0.406015 0.804598
403 3HC 0.406015 0.813953
404 1HE 0.406015 0.786517
405 BCO 0.406015 0.804598
406 GTG 0.405405 0.886076
407 NMN AMP PO4 0.404959 0.87013
408 3D1 0.404762 0.773333
409 3L1 0.404762 0.773333
410 2BA 0.404255 0.915493
411 CMP 0.404255 0.901408
412 VRT 0.40404 0.769231
413 SO8 0.40404 0.789474
414 MCA 0.402985 0.795455
415 COO 0.402985 0.804598
416 CAA 0.402985 0.813953
417 3NZ 0.401869 0.782051
418 G2R 0.401869 0.884615
419 ZZB 0.4 0.77381
420 2FA 0.4 0.813333
421 MC4 0.4 0.76087
422 2CP 0.4 0.795455
Ligand no: 2; Ligand: 5MY; Similar ligands found: 21
No: Ligand ECFP6 Tc MDL keys Tc
1 5IP 1 1
2 5MY 1 1
3 I5P 1 1
4 IP5 1 1
5 I4P 0.782609 1
6 I0P 0.730769 0.965517
7 4IP 0.714286 0.965517
8 IHP 0.652174 1
9 I6P 0.652174 1
10 I3P 0.6 0.933333
11 I3S 0.6 0.933333
12 IP2 0.571429 0.933333
13 ITP 0.533333 0.933333
14 2IP 0.5 0.933333
15 2YN 0.454545 0.965517
16 I7P 0.454545 0.965517
17 I8P 0.454545 0.965517
18 I4D 0.451613 0.9
19 5A3 0.428571 0.8
20 4WZ 0.428571 0.8
21 5A2 0.428571 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5MW8; Ligand: ATP; Similar sites found with APoc: 567
This union binding pocket(no: 1) in the query (biounit: 5mw8.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 2BOS GLA GAL None
2 2BOS GLA GAL GLC None
3 1DCP HBI None
4 4JLS 3ZE None
5 4OCJ NDG 1.05541
6 4WOE 3S5 1.06157
7 4WOE ADP 1.06157
8 4BTK DTQ 1.18694
9 3K5I ADP 1.24069
10 3K5I AIR 1.24069
11 5VLQ ANP 1.27389
12 4NFN 2KC 1.2945
13 4WHZ 3NL 1.2987
14 4PU5 ANP 1.3245
15 2R5T ANP 1.34048
16 1ZNY GDP 1.44928
17 5T96 79J 1.46199
18 4O1P ANP 1.4862
19 3B2Q ATP 1.49254
20 4FE2 ADP 1.56863
21 4FE2 AIR 1.56863
22 2WU6 DKI 1.5748
23 5OKT 9XK 1.59236
24 2QLU ADE 1.59236
25 5VCV 1N1 1.60772
26 1I7L ATP 1.61812
27 6FYL 3NG 1.65289
28 3GGF GVD 1.66113
29 1ZX5 LFR 1.66667
30 5JZJ AN2 1.6835
31 2GQR ADP 1.68776
32 4L9I 8PR 1.69851
33 5MRH Q9Z 1.69851
34 2HGS ADP 1.69851
35 4KBA 1QM 1.69851
36 5W4W 9WG 1.69851
37 6EZ6 C5Z 1.69851
38 5AE9 OKO 1.69851
39 6C1S EFV 1.69851
40 3WO0 ALA 1.70213
41 3WO0 ADP 1.70213
42 3THR C2F 1.70648
43 4TO8 FLC 1.71233
44 2VQD AP2 1.72414
45 1E4E ADP 1.74927
46 2JDR L20 1.75439
47 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 1.75439
48 3MVH WFE 1.75439
49 3D91 REM 1.75953
50 2PVF ACP 1.79641
51 5LPZ ADP 1.80723
52 3ALN ANP 1.83486
53 4K33 ACP 1.84615
54 5ZTN CUR 1.8648
55 1GSA ADP 1.89873
56 3VSV XYS 1.91083
57 5DXT 5H5 1.91083
58 4X7Q 3YR 1.92308
59 3CMJ SRT 1.93548
60 4XH0 ADP 1.98511
61 1TB3 FMN 1.98864
62 1O9U ADZ 2
63 2CFC KPC 2
64 4GYI ADP 2.01511
65 5LPB ADP 2.02703
66 5AWM ANP 2.03046
67 3IT1 TLA 2.04678
68 1RJW ETF 2.0649
69 4WNP 3RJ 2.09059
70 4NFE BEN 2.1097
71 3VOT ADP 2.11765
72 2BMB PMM 2.12314
73 4D1J DGJ 2.12314
74 4OYA 1VE 2.12766
75 4A4X JUP 2.15054
76 3ZGJ RMN 2.15633
77 4DFU QUE 2.17391
78 5DMZ ADP 2.19178
79 2IF8 ADP 2.20386
80 2HK5 1BM 2.22222
81 1SDW IYT 2.2293
82 4IJP 1EH 2.23464
83 3WVR AMP 2.23714
84 1JPA ANP 2.24359
85 3ORK AGS 2.2508
86 3ETH ATP 2.25352
87 1W2D ADP 2.26415
88 1W2D 4IP 2.26415
89 3DNT ATP 2.27273
90 1OKE BOG 2.28426
91 5C1P ADP 2.28758
92 5C1P DAL DAL 2.28758
93 5GZ9 ANP 2.29508
94 5MJA 7O3 2.29508
95 3SLS ANP 2.30263
96 4USF 6UI 2.30263
97 1MJT ITU 2.30548
98 2XVD AS6 2.31788
99 2J7T 274 2.31788
100 5IGI GMP 2.32558
101 5IGI ZIT 2.32558
102 1M0W ANP 2.33546
103 3M2W L8I 2.34114
104 4G31 0WH 2.34114
105 4ZGP ADP 2.38908
106 2Y6O 1N1 2.4055
107 3C1X CKK 2.41287
108 3ZJX BOG 2.42215
109 2VPQ ANP 2.43902
110 3G5D 1N1 2.44755
111 3VPD ANP 2.4911
112 2YAB AMP 2.49307
113 4GO7 THR 2.5
114 4CYI ATP 2.51142
115 3LXN MI1 2.51572
116 4IDT T28 2.52809
117 5LI1 ANP 2.54237
118 3E7S AT2 2.5522
119 1OFZ FUC 2.5641
120 5UR1 YY9 2.57235
121 5T8O 76Z 2.5788
122 1U5R ATP 2.58621
123 3NW7 LGV 2.60586
124 3EKK GS2 2.60586
125 1IR3 ANP 2.61438
126 3BU5 ATP 2.61438
127 5NKB 8ZT 2.61438
128 4YMJ 4EJ 2.63158
129 3VRY B43 2.64317
130 5IH1 GDP 2.64901
131 5IH1 6BQ 2.64901
132 3TM0 B31 2.6616
133 3TM0 ANP 2.6616
134 1K3A ACP 2.67559
135 3HAV ATP 2.67559
136 1Y7P RIP 2.69058
137 6BXI ANP 2.7027
138 4OH4 ANP 2.7027
139 3FSY SCA 2.71084
140 4WB7 ATP 2.71605
141 1CM8 ANP 2.7248
142 4AZW ATP 2.76008
143 4ONA UW1 2.76008
144 5UIU 8CG 2.78638
145 5KO1 6UY 2.82686
146 1DKU AP2 2.83912
147 5HVJ ANP 2.85714
148 3RI1 3RH 2.8754
149 5M06 ADP 2.89855
150 3ORQ ADP 2.91777
151 3NOJ PYR 2.94118
152 6CGD GNP 2.95082
153 6CGD AKN 2.95082
154 5Y86 HRM 2.9724
155 5IM3 DTP 2.9724
156 3DLS ADP 2.98507
157 1C3X 8IG 3.00752
158 4L77 CNL 3.01508
159 4H3Q ANP 3.03867
160 4H3P ANP 3.03867
161 5BVE 4VG 3.04709
162 6F3G CJN 3.05085
163 5I35 ANP 3.05344
164 3DUV KDO 3.05344
165 1NJJ GET 3.05882
166 2ZX2 RAM 3.07692
167 4NW6 2NS 3.09598
168 3V4S ATP 3.10078
169 3V4S ADP 3.10078
170 4YZN 4K5 3.13589
171 4Y93 746 3.13901
172 4WB6 ATP 3.14286
173 2QCS ANP 3.14286
174 1RE8 BD2 3.14286
175 4AZC NGW 3.16742
176 5A6N U7E 3.18021
177 5OES ADP 3.18471
178 3PVW QRX 3.18471
179 4WNK 453 3.18471
180 5UKL SIX 3.18471
181 5JKG 6LF 3.21543
182 5EKO N17 3.2345
183 5OLK DTP 3.25581
184 2GU8 796 3.2641
185 2V7O DRN 3.27381
186 3KRL KRL 3.28358
187 4BHN BH9 3.29341
188 1VJY 460 3.30033
189 4GJ3 0XP 3.31126
190 4U44 3D9 3.31325
191 2JLD AG1 3.33333
192 4I94 ANP 3.33333
193 5TV6 PML 3.33333
194 3TK1 GDP 3.33333
195 5EFQ ADP 3.35821
196 4OUC 5ID 3.36134
197 6G34 5ID 3.36134
198 5H2U 1N1 3.37079
199 3AKK ADP 3.38462
200 5LDQ NAP 3.38983
201 5TDF ADP 3.39506
202 4ZS4 ATP 3.39703
203 5DZT AMP 3.39703
204 4RF7 ARG 3.39703
205 1T36 ORN 3.39703
206 1T36 ADP 3.39703
207 6CZ3 FLJ 3.40909
208 1OI6 TMP 3.41463
209 1QVJ RP5 3.42466
210 5DRB 5FJ 3.43643
211 4E1Z 0MX 3.43643
212 4M3P HCS 3.44828
213 2AQX ATP 3.46021
214 5USZ SKE 3.46021
215 3K4Z CBI 3.46021
216 1ZTH ADP 3.48837
217 3RE4 TO1 3.48837
218 1ZP9 ATP 3.48837
219 5JGA 6KC 3.49206
220 4K37 SAM 3.51351
221 6BYF CIT 3.52941
222 1OUK 084 3.55191
223 2V58 LZJ 3.56347
224 4UAL 3FV 3.57995
225 4BFM ANP 3.59281
226 1IOW ADP 3.59477
227 1IOW PHY 3.59477
228 3W9K MYR 3.59712
229 3IGO ANP 3.60934
230 5TA6 79D 3.60934
231 1VMK GUN 3.61011
232 3AQV TAK 3.62319
233 5DBX ANP 3.65854
234 4CLI 5P8 3.66972
235 4AT3 LTI 3.67893
236 2B9J ADP 3.68272
237 2B9F ADP 3.68272
238 2B9H ADP 3.68272
239 6CQF F97 3.7037
240 4YZC STU 3.7037
241 4NM5 ADP 3.71353
242 6E2O S0L 3.72881
243 2Z7R STU 3.73832
244 5NM7 GLY 3.7594
245 2YRX AMP 3.7694
246 3ZRM ZRM 3.77358
247 4CC6 L5Y 3.77358
248 1ZEI CRS 3.77358
249 3HMO STU 3.80117
250 5T48 MGP 3.80435
251 2PYW ADP 3.80952
252 2FUE M1P 3.81679
253 4OCV ANP 3.82166
254 1OPK P16 3.82166
255 4LOO SB4 3.87812
256 5JDA AMP 3.89972
257 5MY8 RXZ 3.91645
258 2OFV 242 3.97112
259 3UIM ANP 3.98773
260 1TZD ADP 4
261 3F7Z 34O 4
262 2H6B 3C4 4
263 3PLS ANP 4.02685
264 2QF7 AGS 4.03397
265 2XK9 XK9 4.03727
266 4QM9 CYS 4.04624
267 5Y80 IRE 4.05405
268 5WNL STU 4.09357
269 5XVG 8FX 4.09556
270 3SXS PP2 4.10448
271 3DAK ANP 4.13793
272 3PP0 03Q 4.14201
273 5N87 N66 4.15335
274 1NBU PH2 4.20168
275 2YAK OSV 4.21053
276 4Y85 499 4.21687
277 4AUA 4AU 4.23453
278 5LXM ADP 4.24028
279 4FL3 ANP 4.24628
280 2H8H H8H 4.24628
281 2RIF AMP 4.25532
282 6GZD LCI 4.27807
283 5AVF TAU 4.28016
284 1IA9 ANP 4.28571
285 1ZY5 ANP 4.29043
286 3BF8 MLA 4.31373
287 6C0T EE4 4.32277
288 5UPK ANP 4.32432
289 3GC8 B45 4.32432
290 4XYM A12 4.34783
291 4XZ3 ACP 4.34783
292 4EWH T77 4.36364
293 5DEY 59T 4.3771
294 1Y57 MPZ 4.42478
295 5EW9 5VC 4.42804
296 1T27 PCW 4.42804
297 2R7K ACP 4.43213
298 2R7K AMZ 4.43213
299 3VHE 42Q 4.45682
300 2PZI AXX 4.4586
301 5CDH TLA 4.46429
302 4RT1 C2E 4.46429
303 3E5A VX6 4.47761
304 2YW2 ATP 4.48113
305 5F90 LMR 4.48718
306 5F90 GLA GAL BGC 5VQ 4.48718
307 5F90 GLA GAL 4.48718
308 3AB4 THR 4.49438
309 2DTJ THR 4.49438
310 5EO8 TFU 4.50161
311 4QMN DB8 4.51613
312 4ASE AV9 4.53258
313 3FHI ANP 4.54545
314 4NST ADP 4.5584
315 2A19 ANP 4.57143
316 4IX4 ADP 4.57143
317 4LH7 1X8 4.64396
318 1OIJ AKG 4.65116
319 4JGT PYR 4.68227
320 3GNI ATP 4.69208
321 3E8N ATP 4.69208
322 3E8N VRA 4.69208
323 1MEX RAC 4.69484
324 1YQC GLV 4.70588
325 4LRJ ANP 4.73373
326 3TII ANP 4.73684
327 1UCD U5P 4.73684
328 3FHR P4O 4.7619
329 4M69 ANP 4.79233
330 4KS7 X4Z 4.79452
331 1SQL GUN 4.79452
332 4NTO 1PW 4.83092
333 4NZN 2OU 4.84848
334 4NZN ANP 4.84848
335 1V0O INR 4.86111
336 2Z49 AMG 4.86111
337 4U0I 0LI 4.88323
338 3KLL MAL 4.88323
339 3TKI S25 4.95356
340 3TTI KBI 4.9569
341 3VPC ADP 4.96454
342 2HY0 306 4.96894
343 6BFN DL1 4.97076
344 6A1G 9OL 5
345 5BWD FUM 5
346 2XMY CDK 5.03356
347 5EH0 5NW 5.03876
348 2F57 23D 5.04732
349 2CSN CKI 5.05051
350 2GQS ADP 5.06329
351 4AG8 AXI 5.06329
352 4AU8 Z3R 5.06757
353 3FC2 IBI 5.07463
354 4FG8 ATP 5.07937
355 2QK4 ATP 5.0885
356 4KVL PLM 5.09554
357 4MV1 ADP 5.12821
358 6AC9 ANP 5.13514
359 4IZY 1J2 5.14905
360 3DGY 2GP 5.15464
361 5FBN 5WF 5.16605
362 4PNI KQQ 5.16934
363 3BP1 GUN 5.17241
364 4N70 2HX 5.18293
365 3KYF 5GP 5GP 5.19481
366 6GUE FB8 5.22388
367 5EQY 5RA 5.23691
368 4P5Z Q7M 5.26316
369 4B52 RDF 5.26316
370 4OTH DRN 5.27859
371 2BPM 529 5.28302
372 3MPB FRU 5.28455
373 5C4L 4XR 5.29595
374 5C4L SIS 5.29595
375 5CEO 50D 5.33333
376 4CFU 2WC 5.34351
377 4BCM T7Z 5.34351
378 4BCN T9N 5.34351
379 4BCQ TJF 5.34351
380 3HZT J60 5.35332
381 4M1U A2G MBG 5.38721
382 3CY2 MB9 5.41401
383 4CRL C1I 5.41872
384 5LMK 6ZK 5.42636
385 2VZ6 FEF 5.43131
386 2RCA GLY 5.47945
387 2WQN ADP 5.48387
388 3RK1 ATP 5.48523
389 3HQ9 OXL 5.50725
390 5Y4R C2E 5.51724
391 5SWI BMA 5.52017
392 5HES 032 5.53746
393 4DC2 ADE 5.55556
394 6ALW BNV 5.55556
395 1YXM ADE 5.61056
396 4JR7 GNP 5.61497
397 1CBK ROI 5.625
398 4EUU BX7 5.64263
399 3PN1 IVH 5.66038
400 3C0G 3AM 5.69801
401 5DH3 5BS 5.71429
402 5HCY 60D 5.74018
403 2WEL K88 5.8104
404 3E7O 35F 5.83333
405 3X01 AMP 5.85242
406 4OX5 DAL 5.88235
407 3KMW ATP 5.90406
408 6CMJ F6J 5.919
409 2WEI VGG 5.92335
410 5WBF LAC 5.92593
411 3OYW TDG 5.97015
412 5YK1 ANP 5.97345
413 5CKW ANP 5.9867
414 4UX9 ANP 6.04396
415 5KBE IPH 6.11354
416 2IO8 ADP 6.15711
417 2CFM AMP 6.15711
418 4XV1 904 6.16438
419 5AX9 4KT 6.16883
420 4I6H 1C8 6.16883
421 3PDT ADP 6.18182
422 4GID 0GH 6.18557
423 5LI9 ACP 6.28571
424 2VN9 GVD 6.31229
425 5OCQ CIT 6.31579
426 3PTG 932 6.33609
427 5VZ0 ADP 6.36943
428 2ZV2 609 6.37584
429 1PHK ATP 6.37584
430 6GQM F8H 6.40244
431 4WW7 AMP 6.41711
432 3RWP ABQ 6.43087
433 3KN5 ANP 6.46154
434 4CQE CQE 6.47482
435 5YF9 NIO 6.48968
436 4UXL 5P8 6.52174
437 3ZIA ADP 6.52174
438 1OBD ATP 6.53595
439 5EOB 5QQ 6.58307
440 3V8S 0HD 6.58537
441 4TWP AXI 6.64207
442 4Y0X ADP 6.66667
443 4D52 GXL 6.66667
444 4FGC PQ0 6.66667
445 1Q8Y ADE 6.70241
446 1Q8Y ADP 6.70241
447 2AG4 OLA 6.70732
448 2AG4 LP3 6.70732
449 5CPR 539 6.71642
450 1UNH IXM 6.73077
451 5LVP ATP 6.75241
452 3HRD MCN 6.75676
453 5A96 GTP 6.82731
454 3IDB ANP 6.8323
455 4O4F ATP 6.85484
456 4O4F IHP 6.85484
457 5AYE BMA BMA 6.86567
458 5JBX COA 6.89655
459 5JBX MLI 6.89655
460 3N7S 3N7 6.95652
461 3LXK MI1 7.03364
462 4U98 ACP 7.04846
463 4XMF HSM 7.06522
464 3SCH TB6 7.07071
465 5EVY SAL 7.07763
466 2RIO ADP 7.14286
467 4Y8D 49J 7.14286
468 6CZI 38E 7.14286
469 5OMY 9YE 7.16113
470 5ZCT ANP 7.18954
471 1BYG STU 7.19424
472 2XOC ADP 7.27969
473 2X2M X2M 7.32484
474 4F4P 0SB 7.32601
475 1NX4 AKG 7.32601
476 2PVN P63 7.38636
477 4PZ6 GMP 7.44417
478 5TO8 7FM 7.44681
479 2Q7D ANP 7.51445
480 2QX0 PH2 7.54717
481 4L3L 5FI 7.56579
482 4QTB 38Z 7.63158
483 1OGX EQU 7.63359
484 6GIN IR2 7.6412
485 3TXO 07U 7.64873
486 3I0O ADP 7.66962
487 1EHI ADP 7.69231
488 2GOO NDG 7.84314
489 4G17 0VN 7.87879
490 5QIN J2V 7.91139
491 6A4R ASP 7.92453
492 1KJ8 GAR 7.92839
493 1KJ8 ATP 7.92839
494 2RDE C2E 7.96813
495 1Z2P ACP 8.02469
496 1Z2P I3S 8.02469
497 2ZL7 FUC GAL NGA 8.13559
498 6G33 5ID 8.25959
499 6E8I PTR 8.28402
500 6FYV 3NG 8.30861
501 3PE2 E1B 8.30861
502 3W0O ADP 8.30946
503 3W0O HY0 8.30946
504 6GU6 1QK 8.33333
505 1U59 STU 8.36237
506 5X8I SQZ 8.3815
507 3N1S 5GP 8.40336
508 3GQI ACP 8.40708
509 6DW2 HD4 8.43882
510 5JFS 6K0 8.44156
511 4CS9 AMP 8.46561
512 3TDV GDP 8.49673
513 1TQP ATP 8.51064
514 3KAL ADP 8.70488
515 5C03 AGS 8.77193
516 3GC0 AMP 8.81459
517 3Q60 ATP 8.89488
518 3VPB ADP 8.92857
519 4F9C 0SX 9.02778
520 5LN8 GAL 9.16031
521 4JGP PYR 9.21659
522 3O0G 3O0 9.39597
523 4WOV 3SM 9.46372
524 4GLW 0XT 9.5082
525 2RC8 DSN 9.52381
526 5IH9 6BF 9.55224
527 5LXT ACP 9.79021
528 2XSB GDL 10.0671
529 4E93 GUI 10.0796
530 3BZ3 YAM 10.5072
531 4RFM 3P6 10.5263
532 5VC5 96M 10.7266
533 2W5P CL8 10.7383
534 4OAV ACP 10.828
535 4Z4P SAH 10.8434
536 5ODT ADP 10.8696
537 1XJD STU 11.3043
538 5WO4 B7V 11.5894
539 2PUL ACP 11.8388
540 1PK8 ATP 11.8483
541 4UWH JXM 11.8896
542 2DT9 THR 11.976
543 6C7Y ADP 12.2378
544 2BKK ADP 12.426
545 3SRV S19 12.6354
546 3LQV ADE 12.8205
547 3BXO UPP 12.9707
548 5U6C 7YS 13.0159
549 2F2U M77 13.1841
550 5L8L ADP 13.6752
551 1ZUI SKM 13.6905
552 3ZO7 K6H 13.8298
553 5HQ0 LZ9 14.2857
554 1AUX AGS 14.4695
555 2WTN FER 14.741
556 3KIV ACA 15.1899
557 3CF6 SP1 15.5689
558 3H9R TAK 20.1835
559 5EYK 5U5 20.339
560 4Q5H ANP 20.5128
561 1J3R 6PG 21.5789
562 5K2M ADP 22.6415
563 4C2W ANP 23.0769
564 5G1X ADP 25.3968
565 4C2V YJA 27.2727
566 2B9I ADP 28.5714
567 5XG5 A2G 32.4138
Pocket No.: 2; Query (leader) PDB : 5MW8; Ligand: 5MY; Similar sites found with APoc: 2
This union binding pocket(no: 2) in the query (biounit: 5mw8.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1ODM ASV 2.41692
2 2BW7 ECS 3.19635
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