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Receptor
PDB id Resolution Class Description Source Keywords
5N4M 1.59 Å NON-ENZYME: OTHER HUMAN MYELIN PROTEIN P2, MUTANT I43N HOMO SAPIENS FATTY ACID BINDING PROTEIN LIPID BINDING PROTEIN
Ref.: MOLECULAR MECHANISMS OF CHARCOT-MARIE-TOOTH NEUROPA LINKED TO MUTATIONS IN HUMAN MYELIN PROTEIN P2. SCI REP V. 7 6510 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MLT A:203;
Invalid;
none;
submit data
134.087 C4 H6 O5 C([C@...
PLM A:201;
Valid;
none;
submit data
256.424 C16 H32 O2 CCCCC...
VCA A:202;
Valid;
none;
submit data
282.461 C18 H34 O2 CCCCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4BVM 0.93 Å NON-ENZYME: OTHER THE PERIPHERAL MEMBRANE PROTEIN P2 FROM HUMAN MYELIN AT ATOM RESOLUTION HOMO SAPIENS MEMBRANE PROTEIN FABP ULTRAHIGH RESOLUTION
Ref.: ATOMIC RESOLUTION VIEW INTO THE STRUCTURE-FUNCTION RELATIONSHIPS OF THE HUMAN MYELIN PERIPHERAL MEMBRA PROTEIN P2 ACTA CRYSTALLOGR.,SECT.D V. 70 165 2014
Members (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 6EW4 - PLM C16 H32 O2 CCCCCCCCCC....
2 2WUT - PLM C16 H32 O2 CCCCCCCCCC....
3 4BVM - PLM C16 H32 O2 CCCCCCCCCC....
4 6EW2 - PLM C16 H32 O2 CCCCCCCCCC....
5 4D6B - PLM C16 H32 O2 CCCCCCCCCC....
6 6EW5 - PLM C16 H32 O2 CCCCCCCCCC....
7 5N4Q - PLM C16 H32 O2 CCCCCCCCCC....
8 4D6A - PLM C16 H32 O2 CCCCCCCCCC....
9 5N4P - PLM C16 H32 O2 CCCCCCCCCC....
10 5N4M - PLM C16 H32 O2 CCCCCCCCCC....
70% Homology Family (60)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1G74 Kd = 0.3 uM OLA C18 H34 O2 CCCCCCCCC=....
2 3FR5 ic50 = 0.069 uM I4A C22 H22 N2 O3 c1cc(cc(c1....
3 1LIE - PPI C3 H6 O2 CCC(=O)O
4 3FR4 ic50 = 0.049 uM F8A C21 H18 F3 N O2 c1ccc(c(c1....
5 2HNX - PLM C16 H32 O2 CCCCCCCCCC....
6 1ADL Kd = 4.4 uM ACD C20 H32 O2 CCCCCC=C/C....
7 5EDB Ki = 0.1 uM 5M8 C17 H12 Cl N O2 Cc1c(c(c2c....
8 1TOU ic50 = 1 uM B1V C12 H14 F3 N3 O2 S c1c(nc(nc1....
9 1LID - OLA C18 H34 O2 CCCCCCCCC=....
10 1LIF - STE C18 H36 O2 CCCCCCCCCC....
11 3JSQ - HNE C9 H16 O2 CCCCC[C@H]....
12 1TOW ic50 = 0.57 uM CRZ C16 H15 N O2 c1ccc2c(c1....
13 5EDC Ki = 0.022 uM 5M7 C21 H19 Cl N2 O2 c1ccc(cc1)....
14 5HZ8 Ki = 0.016 uM 65Z C21 H18 Cl2 N2 O2 c1ccc(cc1)....
15 3HK1 Ki = 0.67 uM B64 C14 H11 N O5 S2 COC(=O)c1c....
16 1LIC - PPI C3 H6 O2 CCC(=O)O
17 2NNQ Ki < 2 nM T4B C31 H26 N2 O3 CCc1c(c(nn....
18 3FR2 ic50 = 0.59 uM 8CA C20 H19 N O2 c1ccc(cc1)....
19 2ANS Kd = 1.2 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
20 5HZ6 Ki = 0.016 uM 65Y C22 H22 Cl N O2 CC(C)c1ccc....
21 3WBG - 2AN C16 H13 N O3 S c1ccc(cc1)....
22 1B56 - PLM C16 H32 O2 CCCCCCCCCC....
23 5D4A - 57Q C17 H15 N O2 c1ccc(cc1)....
24 5Y0F Ki = 0.21 uM 8JO C18 H14 F N O5 S COc1ccc(c2....
25 5D47 Ki = 0.1 uM L19 C26 H24 N2 O3 COc1cnccc1....
26 5Y12 Ki = 0.59 uM 8JX C16 H19 N O5 S COc1ccc(c2....
27 5D48 Ki = 0.03 uM L96 C28 H31 N3 O3 Cc1c(c(n[n....
28 5D45 Ki = 0.12 uM 57P C26 H23 N O2 c1ccc(cc1)....
29 5Y0X Ki = 7.75 uM 8JR C18 H14 F N O5 S COc1ccc(c2....
30 5Y0G Ki = 0.2 uM 8JL C18 H14 F N O5 S COc1ccc(c2....
31 5Y13 Ki = 1.16 uM 8K0 C15 H16 Br N O4 S c1ccc2c(c1....
32 5URA Ki = 0.4 uM 8KS C28 H22 O4 c1ccc(cc1)....
33 1FDQ Kd = 53.4 nM HXA C22 H32 O2 CCC=C/CC=C....
34 4TKB - DAO C12 H24 O2 CCCCCCCCCC....
35 4TJZ - DKA C10 H20 O2 CCCCCCCCCC....
36 1HMT Kd = 1.64 uM STE C18 H36 O2 CCCCCCCCCC....
37 4TKJ - PLM C16 H32 O2 CCCCCCCCCC....
38 5HZ9 Ki = 0.093 uM 5M8 C17 H12 Cl N O2 Cc1c(c(c2c....
39 4WBK - STE C18 H36 O2 CCCCCCCCCC....
40 3WVM - STE C18 H36 O2 CCCCCCCCCC....
41 4TKH - MYR C14 H28 O2 CCCCCCCCCC....
42 1HMR Kd = 0.28 uM ELA C18 H34 O2 CCCCCCCCC=....
43 1HMS Kd = 0.43 uM OLA C18 H34 O2 CCCCCCCCC=....
44 2HMB - PLM C16 H32 O2 CCCCCCCCCC....
45 2Q9S - EIC C18 H32 O2 CCCCCC=C/C....
46 2QM9 Kd = 17 nM TDZ C24 H27 N O5 S Cc1c(c2c(c....
47 5BVT - PAM C16 H30 O2 CCCCCCC=C/....
48 4AZQ - G2A C23 H46 O4 CCCCCCCCCC....
49 4AZP Ki = 1.26 uM A9M C22 H45 N O2 CCCCCCCCCC....
50 5BVS - EIC C18 H32 O2 CCCCCC=C/C....
51 6EW4 - PLM C16 H32 O2 CCCCCCCCCC....
52 2WUT - PLM C16 H32 O2 CCCCCCCCCC....
53 4BVM - PLM C16 H32 O2 CCCCCCCCCC....
54 6EW2 - PLM C16 H32 O2 CCCCCCCCCC....
55 4D6B - PLM C16 H32 O2 CCCCCCCCCC....
56 6EW5 - PLM C16 H32 O2 CCCCCCCCCC....
57 5N4Q - PLM C16 H32 O2 CCCCCCCCCC....
58 4D6A - PLM C16 H32 O2 CCCCCCCCCC....
59 5N4P - PLM C16 H32 O2 CCCCCCCCCC....
60 5N4M - PLM C16 H32 O2 CCCCCCCCCC....
50% Homology Family (113)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 1G74 Kd = 0.3 uM OLA C18 H34 O2 CCCCCCCCC=....
2 3FR5 ic50 = 0.069 uM I4A C22 H22 N2 O3 c1cc(cc(c1....
3 1LIE - PPI C3 H6 O2 CCC(=O)O
4 3FR4 ic50 = 0.049 uM F8A C21 H18 F3 N O2 c1ccc(c(c1....
5 2HNX - PLM C16 H32 O2 CCCCCCCCCC....
6 1ADL Kd = 4.4 uM ACD C20 H32 O2 CCCCCC=C/C....
7 5EDB Ki = 0.1 uM 5M8 C17 H12 Cl N O2 Cc1c(c(c2c....
8 1TOU ic50 = 1 uM B1V C12 H14 F3 N3 O2 S c1c(nc(nc1....
9 1LID - OLA C18 H34 O2 CCCCCCCCC=....
10 1LIF - STE C18 H36 O2 CCCCCCCCCC....
11 3JSQ - HNE C9 H16 O2 CCCCC[C@H]....
12 1TOW ic50 = 0.57 uM CRZ C16 H15 N O2 c1ccc2c(c1....
13 5EDC Ki = 0.022 uM 5M7 C21 H19 Cl N2 O2 c1ccc(cc1)....
14 5HZ8 Ki = 0.016 uM 65Z C21 H18 Cl2 N2 O2 c1ccc(cc1)....
15 3HK1 Ki = 0.67 uM B64 C14 H11 N O5 S2 COC(=O)c1c....
16 1LIC - PPI C3 H6 O2 CCC(=O)O
17 2NNQ Ki < 2 nM T4B C31 H26 N2 O3 CCc1c(c(nn....
18 3FR2 ic50 = 0.59 uM 8CA C20 H19 N O2 c1ccc(cc1)....
19 2ANS Kd = 1.2 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
20 5HZ6 Ki = 0.016 uM 65Y C22 H22 Cl N O2 CC(C)c1ccc....
21 5L8O - CHD C24 H40 O5 C[C@H](CCC....
22 5L8N Kd = 31 uM 6RQ C9 H11 N3 Cc1cc2c(cc....
23 3WBG - 2AN C16 H13 N O3 S c1ccc(cc1)....
24 5HZ5 Ki = 0.086 uM 65X C21 H19 Cl N6 c1ccc(cc1)....
25 5UR9 Ki = 0.9 uM 8KS C28 H22 O4 c1ccc(cc1)....
26 1B56 - PLM C16 H32 O2 CCCCCCCCCC....
27 5D4A - 57Q C17 H15 N O2 c1ccc(cc1)....
28 5Y0F Ki = 0.21 uM 8JO C18 H14 F N O5 S COc1ccc(c2....
29 5D47 Ki = 0.1 uM L19 C26 H24 N2 O3 COc1cnccc1....
30 5Y12 Ki = 0.59 uM 8JX C16 H19 N O5 S COc1ccc(c2....
31 5D48 Ki = 0.03 uM L96 C28 H31 N3 O3 Cc1c(c(n[n....
32 5D45 Ki = 0.12 uM 57P C26 H23 N O2 c1ccc(cc1)....
33 5Y0X Ki = 7.75 uM 8JR C18 H14 F N O5 S COc1ccc(c2....
34 5Y0G Ki = 0.2 uM 8JL C18 H14 F N O5 S COc1ccc(c2....
35 5Y13 Ki = 1.16 uM 8K0 C15 H16 Br N O4 S c1ccc2c(c1....
36 5URA Ki = 0.4 uM 8KS C28 H22 O4 c1ccc(cc1)....
37 1FDQ Kd = 53.4 nM HXA C22 H32 O2 CCC=C/CC=C....
38 2G78 - REA C20 H28 O2 CC1=C(C(CC....
39 2CBS Ki = 6 nM R13 C23 H30 O2 CC(=C/C(=O....
40 1CBS - REA C20 H28 O2 CC1=C(C(CC....
41 2FR3 Kd = 2 nM REA C20 H28 O2 CC1=C(C(CC....
42 3CWK Kd = 250 nM REA C20 H28 O2 CC1=C(C(CC....
43 3CBS Ki = 58 nM R12 C20 H24 O3 Cc1cc(c(c(....
44 2G79 Kd = 120 nM RET C20 H28 O CC1=C(C(CC....
45 2G7B - AZE C20 H30 CC=C(/C)C=....
46 1CBQ - RE9 C20 H28 O2 CC(=C/C(=O....
47 4TKB - DAO C12 H24 O2 CCCCCCCCCC....
48 4TJZ - DKA C10 H20 O2 CCCCCCCCCC....
49 1HMT Kd = 1.64 uM STE C18 H36 O2 CCCCCCCCCC....
50 4TKJ - PLM C16 H32 O2 CCCCCCCCCC....
51 5HZ9 Ki = 0.093 uM 5M8 C17 H12 Cl N O2 Cc1c(c(c2c....
52 4WBK - STE C18 H36 O2 CCCCCCCCCC....
53 3WVM - STE C18 H36 O2 CCCCCCCCCC....
54 4TKH - MYR C14 H28 O2 CCCCCCCCCC....
55 1HMR Kd = 0.28 uM ELA C18 H34 O2 CCCCCCCCC=....
56 1HMS Kd = 0.43 uM OLA C18 H34 O2 CCCCCCCCC=....
57 2HMB - PLM C16 H32 O2 CCCCCCCCCC....
58 3VG3 - PLM C16 H32 O2 CCCCCCCCCC....
59 3B2H - PLM C16 H32 O2 CCCCCCCCCC....
60 3B2K - PLM C16 H32 O2 CCCCCCCCCC....
61 3VG6 - PLM C16 H32 O2 CCCCCCCCCC....
62 3VG5 - PLM C16 H32 O2 CCCCCCCCCC....
63 3VG7 - PLM C16 H32 O2 CCCCCCCCCC....
64 3STM - PLM C16 H32 O2 CCCCCCCCCC....
65 3VG2 - PLM C16 H32 O2 CCCCCCCCCC....
66 3B2I - PLM C16 H32 O2 CCCCCCCCCC....
67 3B2L - PLM C16 H32 O2 CCCCCCCCCC....
68 3B2J - PLM C16 H32 O2 CCCCCCCCCC....
69 3VG4 - PLM C16 H32 O2 CCCCCCCCCC....
70 1OPB Kd = 50 nM RET C20 H28 O CC1=C(C(CC....
71 2Q9S - EIC C18 H32 O2 CCCCCC=C/C....
72 2QM9 Kd = 17 nM TDZ C24 H27 N O5 S Cc1c(c2c(c....
73 2QO4 - CHD C24 H40 O5 C[C@H](CCC....
74 2QO6 - CHD C24 H40 O5 C[C@H](CCC....
75 2QO5 - CHD C24 H40 O5 C[C@H](CCC....
76 1TW4 - CHD C24 H40 O5 C[C@H](CCC....
77 5BVT - PAM C16 H30 O2 CCCCCCC=C/....
78 3ELZ - CHD C24 H40 O5 C[C@H](CCC....
79 3EM0 - CHD C24 H40 O5 C[C@H](CCC....
80 4AZQ - G2A C23 H46 O4 CCCCCCCCCC....
81 4AZP Ki = 1.26 uM A9M C22 H45 N O2 CCCCCCCCCC....
82 5LJG - PLM C16 H32 O2 CCCCCCCCCC....
83 5LJC Kd = 65 nM RTL C20 H30 O CC1=C(C(CC....
84 5HBS Kd = 18.5 nM RTL C20 H30 O CC1=C(C(CC....
85 5H8T Kd = 18.5 nM RTL C20 H30 O CC1=C(C(CC....
86 5LJE Kd = 250 nM RTL C20 H30 O CC1=C(C(CC....
87 5LJD Kd = 70 nM RTL C20 H30 O CC1=C(C(CC....
88 5LJB Kd = 4.5 nM RTL C20 H30 O CC1=C(C(CC....
89 1CRB - RTL C20 H30 O CC1=C(C(CC....
90 5HA1 Kd = 64.1 nM RNE C20 H31 N CC1=C(C(CC....
91 4QZU Kd = 2 nM RTL C20 H30 O CC1=C(C(CC....
92 4QYN Kd = 2 nM RTL C20 H30 O CC1=C(C(CC....
93 2RCT - RTL C20 H30 O CC1=C(C(CC....
94 4QZT Kd = 2 nM RTL C20 H30 O CC1=C(C(CC....
95 1VYF Kd = 9 nM OLA C18 H34 O2 CCCCCCCCC=....
96 1VYG Kd = 10 nM ACD C20 H32 O2 CCCCCC=C/C....
97 2FT9 - CHD C24 H40 O5 C[C@H](CCC....
98 2FTB - OLA C18 H34 O2 CCCCCCCCC=....
99 1ICM - MYR C14 H28 O2 CCCCCCCCCC....
100 1ICN - OLA C18 H34 O2 CCCCCCCCC=....
101 2IFB Ki = 3.6 uM PLM C16 H32 O2 CCCCCCCCCC....
102 5BVS - EIC C18 H32 O2 CCCCCC=C/C....
103 6EW4 - PLM C16 H32 O2 CCCCCCCCCC....
104 2WUT - PLM C16 H32 O2 CCCCCCCCCC....
105 4BVM - PLM C16 H32 O2 CCCCCCCCCC....
106 6EW2 - PLM C16 H32 O2 CCCCCCCCCC....
107 4D6B - PLM C16 H32 O2 CCCCCCCCCC....
108 6EW5 - PLM C16 H32 O2 CCCCCCCCCC....
109 5N4Q - PLM C16 H32 O2 CCCCCCCCCC....
110 4D6A - PLM C16 H32 O2 CCCCCCCCCC....
111 5N4P - PLM C16 H32 O2 CCCCCCCCCC....
112 5N4M - PLM C16 H32 O2 CCCCCCCCCC....
113 1KQW - RTL C20 H30 O CC1=C(C(CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PLM; Similar ligands found: 62
No: Ligand ECFP6 Tc MDL keys Tc
1 MYR 1 1
2 EW8 1 1
3 TDA 1 1
4 F15 1 1
5 PLM 1 1
6 STE 1 1
7 X90 1 1
8 DAO 1 1
9 KNA 1 1
10 DCR 1 1
11 F23 1 1
12 11A 1 1
13 DKA 1 1
14 OCA 0.956522 1
15 SHV 0.833333 0.952381
16 KTC 0.793103 0.875
17 AZ1 0.73913 0.64
18 6NA 0.72 0.904762
19 ELA 0.71875 0.954545
20 OLA 0.71875 0.954545
21 NER 0.71875 0.954545
22 VCA 0.666667 0.954545
23 PAM 0.666667 0.954545
24 PML 0.625 0.6
25 3LA 0.606061 0.8
26 LEA 0.6 0.809524
27 MYZ 0.588235 0.909091
28 12H 0.586207 0.615385
29 ODD 0.567568 0.913043
30 BRC 0.566667 0.666667
31 14V 0.555556 0.740741
32 M12 0.545455 0.869565
33 14U 0.542857 0.703704
34 EIC 0.538462 0.913043
35 EOD 0.538462 0.7
36 D0G 0.5 0.954545
37 BMJ 0.5 0.954545
38 BNV 0.5 0.954545
39 BUA 0.48 0.666667
40 RCL 0.468085 0.84
41 FTT 0.459459 0.807692
42 HXD 0.459459 0.807692
43 56S 0.459459 0.653846
44 ODT 0.452381 0.782609
45 3X1 0.444444 0.818182
46 LNL 0.44186 0.826087
47 9J6 0.441176 0.666667
48 OOA 0.441176 0.76
49 CUY 0.435897 0.68
50 6UL 0.435897 0.68
51 CNS 0.435897 0.68
52 5UF 0.432432 0.807692
53 243 0.428571 0.807692
54 1QW 0.418605 0.606061
55 GYM 0.418605 0.606061
56 O8N 0.413793 0.75
57 1DO 0.413793 0.75
58 PL3 0.413793 0.75
59 OC9 0.413793 0.75
60 DE1 0.413793 0.75
61 F09 0.413793 0.75
62 T25 0.403846 0.677419
Ligand no: 2; Ligand: VCA; Similar ligands found: 54
No: Ligand ECFP6 Tc MDL keys Tc
1 VCA 1 1
2 PAM 1 1
3 ELA 0.939394 1
4 OLA 0.939394 1
5 NER 0.939394 1
6 MYZ 0.852941 0.954545
7 EIC 0.725 0.956522
8 ODD 0.675 0.956522
9 X90 0.666667 0.954545
10 TDA 0.666667 0.954545
11 STE 0.666667 0.954545
12 EW8 0.666667 0.954545
13 F15 0.666667 0.954545
14 MYR 0.666667 0.954545
15 F23 0.666667 0.954545
16 DCR 0.666667 0.954545
17 11A 0.666667 0.954545
18 DAO 0.666667 0.954545
19 KNA 0.666667 0.954545
20 PLM 0.666667 0.954545
21 DKA 0.666667 0.954545
22 OCA 0.636364 0.954545
23 RCL 0.625 0.88
24 LNL 0.613636 0.869565
25 SHV 0.606061 0.909091
26 KTC 0.564103 0.84
27 ODT 0.555556 0.826087
28 T25 0.54717 0.709677
29 AZ1 0.53125 0.615385
30 10X 0.529412 0.645161
31 6NA 0.529412 0.863636
32 10Y 0.529412 0.645161
33 3X1 0.525 0.863636
34 243 0.519231 0.846154
35 MVC 0.519231 0.617647
36 VA 0.511111 0.692308
37 OLC 0.490566 0.617647
38 OLB 0.490566 0.617647
39 ACD 0.488889 0.956522
40 EOD 0.468085 0.677419
41 78N 0.444444 0.617647
42 78M 0.444444 0.617647
43 3LA 0.44186 0.769231
44 LEA 0.441176 0.772727
45 T24 0.438596 0.769231
46 BRC 0.435897 0.64
47 M12 0.428571 0.833333
48 MPG 0.425926 0.617647
49 9OD 0.422222 0.72
50 14V 0.413043 0.714286
51 BMJ 0.4 0.913043
52 D0G 0.4 0.913043
53 14U 0.4 0.678571
54 BNV 0.4 0.913043
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4BVM; Ligand: VCA; Similar sites found with APoc: 123
This union binding pocket(no: 1) in the query (biounit: 4bvm.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 3UUA 0CZ None
2 4TUZ 36J None
3 4MG9 27K None
4 2ET1 GLV None
5 1KJ1 MAN None
6 5H9Q TD2 None
7 2QA8 GEN None
8 4P6W MOF None
9 4MGB XDH None
10 4MG7 27H None
11 4TV1 36M None
12 2ZFZ ARG None
13 1UO5 PIH None
14 3WW2 LPK None
15 1M2Z DEX None
16 4P6X HCY None
17 4GGZ BTN None
18 4WG0 CHD None
19 5K21 6QF None
20 2BWA GLC BGC None
21 2Q1H AS4 None
22 4CPH LH4 None
23 5L7G 6QE None
24 1IS3 LAT None
25 3AI3 SOL 1.50376
26 6GNO XDI 2.25564
27 4A7W GTP 2.25564
28 2R40 EPH 2.25564
29 1M13 HYF 2.25564
30 1I82 BGC BGC 2.25564
31 1YYE 196 2.25564
32 3HP9 CF1 2.25564
33 6D61 4AA 2.25564
34 4J24 EST 2.25564
35 3OLL EST 2.25564
36 4OIT BMA 2.65487
37 4OIT MAN 2.65487
38 1NKI PPF 3.00752
39 5DG2 GAL GLC 3.00752
40 1P0Z FLC 3.05344
41 5C1M OLC 3.7594
42 4WGF HX2 3.7594
43 1LOP SIN ALA PRO ALA NIT 3.7594
44 5GLT BGC GAL NAG GAL 3.7594
45 2YMZ LAT 3.84615
46 4JNJ BTN 4.34783
47 1N5S ADL 4.46429
48 4URG C2E 4.51128
49 5LWY OLB 4.51128
50 2FCU AKG 4.51128
51 2WHL MAN BMA BMA 4.51128
52 2R5V HHH 4.51128
53 5O0J GLC 4.51128
54 2JIG PD2 4.51128
55 2GWH PCI 4.51128
56 2ZSC BTN 4.51128
57 1ZS6 ADP 4.51128
58 4EKQ NPO 4.51128
59 1L0I PSR 5.12821
60 2P7Q GG6 5.26316
61 3ZGJ RMN 5.26316
62 5ML3 DL3 5.26316
63 4ZU4 4TG 5.26316
64 3Q8U ADP 5.26316
65 2D5X L35 5.26316
66 5JSP DQY 5.26316
67 3I4X DST 5.26316
68 5XQW 8EU 5.26316
69 1SLT NDG GAL 5.26316
70 4B1M FRU FRU 5.94595
71 4YZ5 DAN 6.01504
72 1C1L GAL BGC 6.01504
73 1ZDT PEF 6.01504
74 4WVO 3UZ 6.01504
75 2YKL NLD 6.01504
76 1SQI 869 6.76692
77 3B00 16A 6.76692
78 1ULE GLA GAL NAG 6.76692
79 2HZL PYR 6.76692
80 5NBP BGC BGC BGC 6.76692
81 1JGU HBC 6.76692
82 5UC9 MYR 6.76692
83 3FAL LO2 7.5188
84 2VDY HCY 7.5188
85 4JAW GAL NGT 7.5188
86 3WUD GLC GAL 8.27068
87 4OGQ 7PH 8.27068
88 5INJ 6C7 8.27068
89 3M3E GAL A2G NPO 8.27068
90 4YLZ LAT NAG GAL 8.27068
91 4W6Z ETF 8.27068
92 1WW5 SGA BGC 8.27068
93 3NB0 G6P 8.27068
94 5VNF VAL THR SER VAL VAL 8.27068
95 5T7I LAT NAG GAL 8.27068
96 5Y02 HBX 8.41121
97 1A78 TDG 9.02256
98 2JBM SRT 9.02256
99 2D6M LBT 9.02256
100 3NNT DQA 9.77444
101 1L7P SEP 9.77444
102 3RY9 1CA 9.77444
103 5HCN DAO 10.5263
104 1Q7E MET 11.2782
105 3WV6 GAL BGC 11.2782
106 3WG3 A2G GAL NAG FUC 11.2782
107 5TPV TYD 12.0301
108 2GGH NLQ 12.0301
109 1GJW GLC 12.782
110 1SR7 MOF 12.782
111 2BP1 FLC 12.782
112 3KP6 SAL 13.5338
113 4E2J MOF 13.5338
114 6FOF LAT 14.2857
115 5W7B MYR 15.0376
116 1VR0 3SL 15.7895
117 2BCG GER 15.7895
118 5FXD H7Y 16.5414
119 5LGA 6VH 17.2932
120 3PGU OLA 21.0526
121 3STK PLM 30.303
122 1LFO OLA 31.25
123 1MDC PLM 39.3939
Pocket No.: 2; Query (leader) PDB : 4BVM; Ligand: PLM; Similar sites found with APoc: 105
This union binding pocket(no: 2) in the query (biounit: 4bvm.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 3UUA 0CZ None
2 4MG9 27K None
3 1KJ1 MAN None
4 5H9Q TD2 None
5 4P6X HCY None
6 4TV1 36M None
7 4MGB XDH None
8 5L7G 6QE None
9 1UO5 PIH None
10 4MG7 27H None
11 1M2Z DEX None
12 2QA8 GEN None
13 5K21 6QF None
14 2AG4 LP3 None
15 4WG0 CHD None
16 1IS3 LAT None
17 4GGZ BTN None
18 2Q1H AS4 None
19 5WGQ EST None
20 6GNO XDI 2.25564
21 4A7W GTP 2.25564
22 2R40 EPH 2.25564
23 1YYE 196 2.25564
24 4RZB NFQ 2.25564
25 1U3R 338 2.25564
26 3OLL EST 2.25564
27 6D61 4AA 2.25564
28 4OIT BMA 2.65487
29 4OIT MAN 2.65487
30 1NKI PPF 3.00752
31 1WUB OTP 3.00752
32 5DG2 GAL GLC 3.00752
33 1P0Z FLC 3.05344
34 4WGF HX2 3.7594
35 2YMZ LAT 3.84615
36 4JNJ BTN 4.34783
37 1N5S ADL 4.46429
38 4URG C2E 4.51128
39 5LWY OLB 4.51128
40 2FCU AKG 4.51128
41 1ZS6 ADP 4.51128
42 2R5V HHH 4.51128
43 4EKQ NPO 4.51128
44 2ZSC BTN 4.51128
45 2Q0D ATP 4.51128
46 1L0I PSR 5.12821
47 3ZGJ RMN 5.26316
48 4EE7 PIS 5.26316
49 5ML3 DL3 5.26316
50 2P7Q GG6 5.26316
51 4ZU4 4TG 5.26316
52 2D5X L35 5.26316
53 5MWY YNU 5.26316
54 5XQW 8EU 5.26316
55 3I4X DST 5.26316
56 3Q8U ADP 5.26316
57 5JSP DQY 5.26316
58 1SLT NDG GAL 5.26316
59 4B1M FRU FRU 5.94595
60 1C1L GAL BGC 6.01504
61 1ZDT PEF 6.01504
62 5G5W R8C 6.01504
63 4WVO 3UZ 6.01504
64 1HG4 LPP 6.01504
65 4YZ5 DAN 6.01504
66 1SQI 869 6.76692
67 2GVV DI9 6.76692
68 2YFB SIN 6.76692
69 2HZL PYR 6.76692
70 5NBP BGC BGC BGC 6.76692
71 1ULE GLA GAL NAG 6.76692
72 5UC9 MYR 6.76692
73 4CCK OGA 7.5188
74 2VDY HCY 7.5188
75 3WUD GLC GAL 8.27068
76 5INJ 6C7 8.27068
77 4OGQ 7PH 8.27068
78 3M3E GAL A2G NPO 8.27068
79 4W6Z ETF 8.27068
80 1WW5 SGA BGC 8.27068
81 3NB0 G6P 8.27068
82 5VNF VAL THR SER VAL VAL 8.27068
83 5Y02 HBX 8.41121
84 1A78 TDG 9.02256
85 2JBM SRT 9.02256
86 2D6M LBT 9.02256
87 3NNT DQA 9.77444
88 1L7P SEP 9.77444
89 5HCN DAO 10.5263
90 1Q7E MET 11.2782
91 3WV6 GAL BGC 11.2782
92 1GJW GLC 12.782
93 1SR7 MOF 12.782
94 2BP1 FLC 12.782
95 5WL1 CUY 13.1313
96 3KP6 SAL 13.5338
97 4E2J MOF 13.5338
98 5UFS 1TA 13.5338
99 6FOF LAT 14.2857
100 5W7B MYR 15.0376
101 5FXD H7Y 16.5414
102 4JH6 FCN 21.8045
103 3STK PLM 30.303
104 1LFO OLA 31.25
105 1MDC PLM 39.3939
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