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Receptor
PDB id Resolution Class Description Source Keywords
5T4J 2.23 Å NON-ENZYME: TRANSCRIPT_TRANSLATE PLP AND GABA TRIGGER GABR-MEDIATED TRANSCRIPTION REGULATION BACILLUS SUBSIDIES VIA EXTERNAL ALDIMINE FORMATION BACILLUS SUBTILIS GABR MOCR PLP GABA EXTERNAL ALDIMINE TRANSCRIPTION REGU
Ref.: PLP AND GABA TRIGGER GABR-MEDIATED TRANSCRIPTION RE IN BACILLUS SUBTILIS VIA EXTERNAL ALDIMINE FORMATIO PROC. NATL. ACAD. SCI. V. 114 3891 2017 U.S.A.
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PLP ABU B:501;
Valid;
none;
Kd = 2.6 mM
329.225 n/a P(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5T4J 2.23 Å NON-ENZYME: TRANSCRIPT_TRANSLATE PLP AND GABA TRIGGER GABR-MEDIATED TRANSCRIPTION REGULATION BACILLUS SUBSIDIES VIA EXTERNAL ALDIMINE FORMATION BACILLUS SUBTILIS GABR MOCR PLP GABA EXTERNAL ALDIMINE TRANSCRIPTION REGU
Ref.: PLP AND GABA TRIGGER GABR-MEDIATED TRANSCRIPTION RE IN BACILLUS SUBTILIS VIA EXTERNAL ALDIMINE FORMATIO PROC. NATL. ACAD. SCI. V. 114 3891 2017 U.S.A.
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 291 families.
1 5X03 - PLP ABU n/a n/a
2 5T4K - 76U C13 H20 F N2 O7 P Cc1c(c(c(c....
3 5T4J Kd = 2.6 mM PLP ABU n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 247 families.
1 5X03 - PLP ABU n/a n/a
2 5T4K - 76U C13 H20 F N2 O7 P Cc1c(c(c(c....
3 5T4J Kd = 2.6 mM PLP ABU n/a n/a
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 5X03 - PLP ABU n/a n/a
2 5T4K - 76U C13 H20 F N2 O7 P Cc1c(c(c(c....
3 5T4J Kd = 2.6 mM PLP ABU n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PLP ABU; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 PLP ABU 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5T4J; Ligand: PLP ABU; Similar sites found with APoc: 53
This union binding pocket(no: 1) in the query (biounit: 5t4j.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1T27 PCW 1.84502
2 1OXO IK2 1.91781
3 3OG9 MLT 2.39234
4 3WY2 BGC 2.46575
5 3PD6 PMP 2.73973
6 3PDB PMP 2.73973
7 1AJS PLA 3.0137
8 6DND PLP 3.0137
9 5W19 9TD 3.0137
10 5X2Z 3LM 3.83562
11 1TOI HCI 4.10959
12 1C7O PPG 4.10959
13 1JS3 PLP 142 4.38356
14 5MUJ RAM ARA RAM 8OQ RAM GAL XXM 8PK 4.38356
15 2HOX P1T 5.20548
16 1GEX PLP HSA 5.33708
17 4M2K PLP 5.47945
18 5F3I 5UJ 5.55556
19 6C3C EJ1 6.0274
20 4JX1 CAH 6.19469
21 3BWN PMP 6.30137
22 3BWN PMP PHE 6.30137
23 1E8G FCR 6.57534
24 1E8G FAD 6.57534
25 1LW4 TLP 6.62824
26 1LW4 PLP 6.62824
27 5LXT ACP 8.08989
28 2R5C C6P 14.5205
29 2R5E QLP 14.5205
30 6C92 EQJ 14.5205
31 6C8T EQJ 14.5205
32 6C9B EGV 14.5205
33 2X5F PLP 14.7945
34 4RKC PMP 18.9041
35 3EI9 PL6 20.5479
36 4JE5 PLP 22.7397
37 4JE5 PMP 22.7397
38 1XI9 PLP 23.2877
39 3CQ5 PMP 23.8356
40 4R5Z SIN 25.7534
41 4R5Z PMP 25.7534
42 1LC8 33P 25.8242
43 2R2N KYN 26.5753
44 2R2N PMP 26.5753
45 2X5D PLP 28.4932
46 5IWQ PLP 28.7671
47 1GDE GLU PLP 28.7671
48 1GCK ASP PLP 29.0411
49 4FL0 PLP 29.589
50 1UU1 PMP HSA 30.4478
51 1M7Y PPG 35.0685
52 2ZC0 PMP 43.0137
53 2ZYJ PGU 44.0806
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