Receptor
PDB id Resolution Class Description Source Keywords
5TB5 2 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF FULL-LENGTH FARNESYLATED AND METHYLATED COMPLEX WITH PDE-DELTA (CRYSTAL FORM I - WITH PARTIALLY DISH YPERVARIABLE REGION) HOMO SAPIENS KRAS4B PDEDELTA PDE6DELTA RAS KRAS ONCOPROTEIN
Ref.: STRUCTURAL BASIS OF RECOGNITION OF FARNESYLATED AND METHYLATED KRAS4B BY PDE DELTA. PROC.NATL.ACAD.SCI.USA V. 113 E6766 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO B:201;
D:201;
Invalid;
Invalid;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
GDP C:202;
A:202;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
FAR C:201;
A:201;
Invalid;
Invalid;
none;
none;
submit data
206.367 C15 H26 CC=C(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5TB5 2 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF FULL-LENGTH FARNESYLATED AND METHYLATED COMPLEX WITH PDE-DELTA (CRYSTAL FORM I - WITH PARTIALLY DISH YPERVARIABLE REGION) HOMO SAPIENS KRAS4B PDEDELTA PDE6DELTA RAS KRAS ONCOPROTEIN
Ref.: STRUCTURAL BASIS OF RECOGNITION OF FARNESYLATED AND METHYLATED KRAS4B BY PDE DELTA. PROC.NATL.ACAD.SCI.USA V. 113 E6766 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 5TB5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 217 families.
1 5TB5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 5TB5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5TB5; Ligand: GDP; Similar sites found: 440
This union binding pocket(no: 1) in the query (biounit: 5tb5.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4QRH 0O2 0.0006816 0.45967 3.24324
2 3FIU POP 0.0154 0.41196 3.24324
3 4E03 ADP 0.00001575 0.51534 3.78378
4 1AQU A3P 0.006569 0.41035 3.78378
5 5L3W GDP 0.000003909 0.55134 4
6 2ZFI ADP 0.00001528 0.53908 4
7 4KBF AMP 0.00224 0.44181 4
8 2J5V PCA 0.00815 0.44022 4
9 4TMK T5A 0.006632 0.43031 4
10 5L3V GDP 0.000001145 0.57535 4.32432
11 1JI0 ATP 0.000008933 0.56702 4.32432
12 5H56 TYD 0.00003779 0.53415 4.32432
13 5H56 ADP 0.00003779 0.53415 4.32432
14 5L3S GNP 0.00000158 0.4886 4.32432
15 3B7G ANP 0.0003508 0.46892 4.32432
16 2Q2Y MKR 0.0003677 0.49799 4.66667
17 2Q2Y ADP 0.0003895 0.49799 4.66667
18 3BOS CDP 0.0001284 0.49537 4.66667
19 5I0H ADP BEF 0.0001718 0.4873 4.66667
20 2Y65 ADP 0.000002498 0.48186 4.66667
21 1P3D ANP 0.008449 0.40912 4.66667
22 3EZ2 ADP 0.00002901 0.53346 4.77387
23 3WY9 GDP 0.00000000004596 0.81496 4.86486
24 1YRB GDP 0.00000000001804 0.79634 4.86486
25 3WYA GDP 0.0000000001688 0.71194 4.86486
26 1D2E GDP 0.000000002862 0.67155 4.86486
27 4AG5 ADP 0.000006929 0.58024 4.86486
28 3B9Q MLI 0.00009365 0.52287 4.86486
29 3IO3 ADP 0.0006933 0.489 4.86486
30 1G6H ADP 0.000002741 0.46201 4.86486
31 1VHT BA3 0.0003729 0.46224 5.04587
32 1BG2 ADP 0.0000008595 0.48056 5.23077
33 5M04 GDP 0.0000000001602 0.78864 5.33333
34 2DPY ADP 0.00003513 0.53736 5.33333
35 3ZFD ANP 0.0002224 0.47235 5.33333
36 3FWY ADP 0.0000008278 0.58829 5.40541
37 1SQ5 ADP 0.000008014 0.5446 5.40541
38 5LB3 ADP 0.00006529 0.51635 5.40541
39 5J1J ANP 0.000003391 0.48391 5.40541
40 4IEE AGS 0.0005782 0.47038 5.40541
41 3DKP ADP 0.0002247 0.45655 5.40541
42 3VM7 GLC 0.01124 0.41694 5.40541
43 2Z5F A3P 0.009746 0.40625 5.40541
44 4KVX ACO 0.01371 0.40723 5.76923
45 4BAS GNP 0.00000009815 0.64004 5.94595
46 1FP6 ADP 0.000004189 0.55316 5.94595
47 1ION ADP 0.00002409 0.5158 5.94595
48 3COB ADP 0.0000005013 0.50493 5.94595
49 2ZPA ADP 0.00004204 0.47063 5.94595
50 3ZQ6 ADP ALF 0.000008899 0.44615 5.94595
51 5K5Z ANP 0.00007452 0.43193 5.94595
52 2ZE7 DST 0.004712 0.42928 5.94595
53 2ZE7 AMP 0.0102 0.41186 5.94595
54 1M7G ADX 0.00005775 0.52703 6
55 5I34 GDP 0.00002388 0.52274 6
56 1M7G ADP 0.00007786 0.51736 6
57 1M7G AV2 0.000005219 0.51214 6
58 4R43 GDP 0.00006988 0.50786 6
59 4D81 ADP 0.00008476 0.47939 6
60 3BER AMP 0.004429 0.42261 6
61 1GOJ ADP 0.0000001961 0.67396 6.48649
62 3E70 GDP 0.000001996 0.57244 6.48649
63 1YQT ADP 0.00001522 0.56305 6.48649
64 5IRN ADP 0.00003221 0.49739 6.48649
65 5BQ5 ADP BEF 0.00006524 0.49632 6.48649
66 1QF5 RPL 0.005979 0.47574 6.48649
67 1QF5 GDP 0.005979 0.47574 6.48649
68 3DZD ADP 0.0002986 0.45686 6.48649
69 2X7I CIT 0.001762 0.41884 6.48649
70 2ZJ5 ADP 0.0187 0.40314 6.48649
71 3IIJ ADP 0.000002003 0.58081 6.66667
72 2QZ4 ADP 0.00003618 0.50785 6.66667
73 3FYH ADP 0.000344 0.47947 6.66667
74 4QOS ADP 0.0002104 0.47344 6.66667
75 4TTQ ATP 0.0001201 0.4688 6.66667
76 3Q9L ATP 0.0001212 0.46394 6.66667
77 2GDJ ANP 0.0001709 0.46052 6.66667
78 1P9B GDP 0.002943 0.45559 6.66667
79 1KO8 6PG 0.0001247 0.45303 6.66667
80 2XAU ADP 0.0008577 0.44596 6.66667
81 2BEK ATP 0.0001438 0.43564 7.00389
82 1LVG ADP 0.0000009412 0.61576 7.02703
83 2XTN GTP 0.0000003825 0.61537 7.02703
84 1OXV ANP 0.00003379 0.47664 7.02703
85 3T34 GDP 0.000008577 0.47566 7.02703
86 2WHX ADP 0.00002196 0.46126 7.02703
87 5LTJ ADP 0.0002726 0.45983 7.02703
88 2JLR ANP 0.0003981 0.45047 7.02703
89 5MEX SZZ 0.01225 0.42174 7.02703
90 5MEX PAP 0.005402 0.41622 7.02703
91 3RC3 ANP 0.01031 0.40954 7.02703
92 3FVQ ATP 0.0002152 0.43336 7.24234
93 4RD0 GDP 0.0000000009011 0.7346 7.33333
94 4PX9 ADP 0.0001083 0.50568 7.33333
95 1XKV ATP 0.0001779 0.47671 7.33333
96 5VGR GDP 0.0001619 0.45747 7.33333
97 3Q9T FAY 0.01684 0.41592 7.33333
98 3IUY AMP 0.003362 0.41404 7.33333
99 5IRR GSP 0.00000183 0.5047 7.56757
100 1T8U A3P 0.01309 0.40029 7.56757
101 1T5C ADP 0.000001936 0.46915 7.73639
102 4H1V GNP 0.000001777 0.54179 7.85908
103 1XPJ TLA 0.008908 0.4168 7.93651
104 2RCN GDP 0.000000000008438 0.835 8
105 2PZE ATP 0.000004964 0.59528 8
106 4WZ6 ATP 0.00001944 0.55718 8
107 4V03 ADP 0.000007114 0.53964 8
108 4RZ3 ADP 0.00001403 0.53223 8
109 1NJF AGS 0.00004736 0.51547 8
110 1NJF ADP 0.00004421 0.51206 8
111 4GOX A3P 0.000239 0.48491 8
112 4IDN GNP 0.0002482 0.42408 8
113 4P32 ADP 0.0005309 0.41074 8.03213
114 3EC1 GDP 0.0000000007111 0.73145 8.10811
115 3TK1 GDP 0.00000000006207 0.69002 8.10811
116 2VVG ADP 0.0000002104 0.67087 8.10811
117 3LRE ADP 0.0000002113 0.67085 8.10811
118 4LYA ATP 0.00001952 0.52678 8.10811
119 1CS4 GSP 0.000000033 0.52148 8.10811
120 1AZT GSP 0.0000000241 0.51521 8.10811
121 3TBK ANP 0.000268 0.49335 8.10811
122 5WRJ A3P 0.002076 0.44284 8.10811
123 2ZPT A3P 0.04623 0.40505 8.10811
124 2JAQ DCP 0.0007157 0.40009 8.10811
125 1JJV ATP 0.00001669 0.55978 8.64865
126 2OFW ADX 0.0001317 0.51999 8.64865
127 3UIE ANP 0.00004238 0.50475 8.64865
128 1R6B ADP 0.00006235 0.50352 8.64865
129 5M7P ADP 0.0002517 0.47739 8.64865
130 5HR5 ADP 0.0002448 0.47558 8.64865
131 5HR5 FLC 0.008559 0.4237 8.64865
132 3WXM GTP 0.00000001665 0.6847 8.66667
133 1KK1 GNP 0.0000000004577 0.67782 8.66667
134 3H4S ADP 0.0000006972 0.63893 8.66667
135 4YDS ATP 0.00001708 0.55298 8.66667
136 5GVR LMR 0.0001337 0.51544 8.66667
137 1TAD ALF 0.00000002635 0.51377 8.66667
138 1TAD GDP 0.00000002635 0.51377 8.66667
139 4FRZ ADP 0.00000276 0.49596 8.66667
140 1Z6T ADP 0.00005665 0.47482 8.66667
141 4LJ9 ACP 0.0003868 0.47272 8.66667
142 4FCW ADP 0.0001699 0.47047 8.66667
143 3ZS9 ADP ALF 0.00001159 0.44351 8.66667
144 2WOJ ADP ALF 0.00001266 0.44205 8.66667
145 1SKQ GDP 0.000000001582 0.65761 9.18919
146 5IFS ADP 0.00009415 0.48915 9.18919
147 1OE0 TTP 0.001018 0.46082 9.18919
148 1FNN ADP 0.0001428 0.45077 9.18919
149 4A4Z ANP 0.003424 0.42791 9.18919
150 5GOE GDP 0.000000006217 0.6773 9.33333
151 1G7C 5GP 0.0000001603 0.63268 9.33333
152 1JWY GDP 0.0000006151 0.59092 9.33333
153 1JWY ADP 0.00009503 0.47957 9.33333
154 2OZE AGS 0.003076 0.45669 9.33333
155 5CUQ NSC 0.01946 0.4075 9.33333
156 3BFX A3P 0.00238 0.40596 9.33333
157 4CVN ADP 0.0000033 0.58858 9.48905
158 1W5T ANP 0.0006651 0.46016 9.70874
159 1W5T ADP 0.001473 0.44002 9.70874
160 2WIC GNP 0.00000006473 0.64111 9.72973
161 1Y63 ADP 0.000007417 0.51713 9.72973
162 5MVR ADP 0.00002941 0.49256 10
163 4JLV ADP 0.0002097 0.49175 10
164 5MZN ADP 0.0003585 0.48705 10
165 2WJG GDP 0.000000002179 0.72094 10.2703
166 2QEN ADP 0.00005499 0.50517 10.2703
167 4XGU ADP 0.00008572 0.47066 10.2703
168 2XT3 ADP 0.0000006969 0.63753 10.6667
169 3H86 AP5 0.0002846 0.49812 10.6667
170 1IN4 ADP 0.00009879 0.49604 10.6667
171 2KIN ADP 0.0000007905 0.48071 10.6667
172 1OS1 ATP 0.0005939 0.47521 10.6667
173 1OS1 PYR 0.0006403 0.47521 10.6667
174 1UKZ ADP 0.0009574 0.47113 10.6667
175 4WOP CTP 0.0001023 0.45019 10.6667
176 1R0X ATP 0.0002653 0.44462 10.6667
177 2C77 GNP 0.000000007263 0.68922 10.8108
178 2C78 GNP 0.000000002235 0.60725 10.8108
179 4NON GDP 0.000000009931 0.52687 10.8108
180 1NY5 ADP 0.000205 0.45334 10.8108
181 4ZKD GDP 0.00000002755 0.52549 11.3333
182 2OBM ADP 0.0001161 0.52141 11.3333
183 4J0Q GDP 0.00000000009205 0.80032 11.3514
184 2FH5 GTP 0.00000000007389 0.67639 11.3514
185 1JJ7 ADP 0.000001629 0.62896 11.3514
186 1IWE IMP 0.0002933 0.54371 11.3514
187 5G41 AP5 0.0008646 0.48632 11.3514
188 1ZIN AP5 0.0007928 0.48272 11.3514
189 4R98 GNH 0.0000002156 0.62659 11.4391
190 2WJH GDP 0.00000001125 0.6527 11.4458
191 2WJH FLC 0.000003043 0.55624 11.4458
192 2PL3 ADP 0.0001775 0.49527 11.8919
193 2IXE ATP 0.0003464 0.47536 11.8919
194 5J1S ATP 0.0004009 0.40757 11.8919
195 1HTW ADP 0.00003148 0.50129 12
196 1U0J ADP 0.000768 0.42557 12
197 1G3Q ADP 0.00000226 0.56995 12.4324
198 3B5J 12D 0.00002709 0.54299 12.4324
199 4YMU ATP 0.00003619 0.52879 12.4324
200 1XX6 ADP 0.0001412 0.5144 12.4324
201 4U00 ADP 0.000002927 0.46137 12.4324
202 2FAH GDP 0.00009297 0.47944 12.6667
203 1B7T ADP 0.0002464 0.47035 12.6667
204 1KK8 BEF ADP 0.0001767 0.45503 12.6667
205 4PJ3 ANP 0.001485 0.4271 12.6667
206 4LC1 GDP 0.0000000007499 0.74285 12.973
207 3PQC GDP 0.00000001431 0.66101 12.973
208 1V8K ANP 0.00003134 0.52433 12.973
209 3A4M ADP 0.000003568 0.50353 12.973
210 5L3R GCP 0.000001541 0.48823 12.973
211 2XTZ GSP 0.000000007502 0.55754 13.3333
212 4PFO ADP 0.00003637 0.52733 13.3333
213 2FNA ADP 0.00006877 0.44262 13.3333
214 2VB6 ADP BEF 0.00005664 0.44057 13.3333
215 3EWA ANP 0.00006879 0.50818 13.354
216 3CNL GNP 0.00000000094 0.6624 13.3588
217 4KFU ACP 0.00001075 0.47705 13.5135
218 5E5U MLI 0.01372 0.40763 13.5135
219 2CBZ ATP 0.0000008555 0.64413 13.9241
220 2HCJ GDP 0.00000000001831 0.83436 14
221 3U6B GDP 0.00000000002339 0.8292 14
222 5JBQ GDP 0.00000000008037 0.78871 14
223 3U6K GDP 0.0000000001356 0.77797 14
224 1D8T GDP 0.00000000006292 0.72784 14
225 4P3Y GDP 0.00000000002371 0.72444 14
226 4G5G GDP 0.00000000009384 0.72092 14
227 2BVN GNP 0.000000000584 0.70067 14
228 4PC3 GDP 0.000000001871 0.67999 14
229 1F9V ADP 0.000002541 0.60201 14
230 5N69 ADP 0.00001624 0.50986 14
231 3KTA AP5 0.0001607 0.46725 14
232 4IOK ADP 0.003667 0.46488 14
233 4IOK XPO 0.003024 0.46442 14
234 2B8W ALF 5GP 0.0007964 0.46237 14
235 5XDR ADP 0.0006072 0.45793 14
236 1YTM ATP 0.0001773 0.44053 14
237 3QF7 ANP 0.0005309 0.42745 14
238 4NCN GTP 0.0000000006072 0.60938 14.0541
239 4TMZ GSP 0.0000000006905 0.60775 14.0541
240 1OYY AGS 0.003528 0.42729 14.0541
241 5TVF PUT 0.02091 0.40465 14.1176
242 1MKY GDP 0.00000000001572 0.82222 14.5946
243 3CX8 GSP 0.00000002807 0.68178 14.5946
244 1ZCB GDP 0.00000002147 0.67949 14.5946
245 3AB3 GDP 0.00000001594 0.67346 14.5946
246 3RLF ANP 0.0002513 0.48389 14.5946
247 2AWN ADP 0.0000002425 0.47493 14.5946
248 1QHG ATP 0.00642 0.40874 14.6667
249 4HI0 GDP 0.00000002336 0.5899 15.1351
250 5FTB ANP 0.0001983 0.47459 15.6757
251 4OI4 ATP 0.0007498 0.46173 15.6757
252 5FHD ADP ALF 0.0001518 0.43855 15.6757
253 4QM7 GTP 0.00001152 0.54488 15.7895
254 3ZIA ADP 0.00006155 0.50027 16
255 3ZIA ATP 0.00004165 0.49563 16
256 1PUJ GNP 0.00000000437 0.66375 16.2162
257 2IYL GDP 0.0000009935 0.59521 16.2162
258 4ZG4 VO4 ADP 0.00002108 0.45195 16.2162
259 1QHH ATP 0.006235 0.41122 16.5217
260 4KAX GTP 0.000000002944 0.60466 16.568
261 3NHB ADP 0.00001143 0.56901 16.6667
262 4HSE ADP 0.00001597 0.53079 16.7568
263 5EE5 GTP 0.0000000002387 0.76139 16.9591
264 2X77 GDP 0.0000000001626 0.76101 17.2973
265 4BQS ADP 0.00003407 0.52262 17.2973
266 4PPF FLC 0.0000107 0.57925 17.8378
267 1IHU AF3 0.000002211 0.49832 17.8378
268 1IHU ADP 0.000002509 0.48635 17.8378
269 2ZR9 DTP 0.000225 0.48385 17.8378
270 4MKF AP5 0.001054 0.47772 17.8378
271 3N5C GDP 0.0000000005452 0.74939 17.9012
272 3PCR GTP 0.000000003157 0.59367 17.9012
273 3VMF GTP 0.00000000914 0.54947 18
274 2CHG ANP 0.00006916 0.50062 19.4595
275 2D7D ADP 0.0004766 0.44356 19.4595
276 1D2N ANP 0.001673 0.40246 19.4595
277 5CK5 GDP 0.0000000001072 0.70319 20
278 3W5J GDP 0.0000003539 0.64631 20.5405
279 3DEF GDP 0.0000002289 0.61038 20.5405
280 5H67 ATP 0.002654 0.42836 21.25
281 1GOT GDP 0.0000000432 0.65659 21.3333
282 5X40 ACP 0.0005739 0.46715 21.3333
283 2OM2 GDP 0.00000003665 0.58467 22
284 1Y3A GDP 0.00000002404 0.56875 22
285 1FQJ GDP 0.00000002455 0.56413 22
286 1GP2 GDP 0.00000003554 0.56176 22
287 1FQK GDP 0.00000009636 0.54598 22
288 1SVK ALF GDP 0.000000009136 0.52227 22
289 2ODE ALF GDP 0.00000002896 0.51282 22
290 1BH2 GSP 0.00000009458 0.49994 22
291 1FQK ALF 0.007921 0.42392 22
292 1FQJ ALF 0.008415 0.42229 22
293 2C04 GCP 0.00006296 0.47953 22.1622
294 4XTR ADP 0.000007454 0.5029 22.6667
295 4XTR ATP 0.000009756 0.47038 22.6667
296 4XVU ATP 0.00001068 0.46923 22.6667
297 3VX3 ADP 0.00001988 0.52799 22.7027
298 2V7Q ATP 0.00003875 0.50651 22.7027
299 2V7Q ADP 0.00002759 0.49383 22.7027
300 1W0J ADP 0.00004453 0.49188 22.7027
301 1W0J ADP BEF 0.0001022 0.45613 22.7027
302 2CK3 ANP 0.000115 0.45451 22.7027
303 2CK3 ADP 0.0001117 0.42945 22.7027
304 5HCN GCP 0.0000000001633 0.76092 23.2432
305 5FG3 GDP 0.00000000001699 0.73135 23.2432
306 1NRJ GTP 0.00000003951 0.58052 23.7838
307 1G7S GDP 0.0000000009378 0.72591 24.3243
308 1DAR GDP 0.000000005366 0.70243 24.3243
309 2GK6 ADP 0.0004734 0.42598 24.6667
310 4B47 GDP 0.00000000001186 0.84352 25.4054
311 3T1O GDP 0.0000000137 0.66186 25.4054
312 3T12 GDP ALF 0.00000003695 0.56898 25.4054
313 3KJI ADP 0.0007181 0.48365 25.4054
314 4M9Q GNP 0.000000001521 0.61486 25.9459
315 2W83 GTP 0.0000000009991 0.61047 25.9459
316 2A5F GTP 0.000000002278 0.58599 26.4865
317 1WF3 GNP 0.0000000103 0.53527 27.027
318 3DOE GTP 0.0000000002873 0.62718 27.5676
319 4DCT GDP 0.0000000000385 0.78985 28.1081
320 1O3Y GTP 0.000000001349 0.72982 29.1892
321 1MR3 G3D 0.0000000003996 0.71422 29.1892
322 1J2J GTP 0.000000000516 0.61794 29.1892
323 2J59 GTP 0.0000000006688 0.61541 29.1892
324 1S9D GDP 0.00000000136 0.71846 29.7297
325 1RE0 GDP 0.000000000123 0.69913 29.7297
326 5KSP GDP 0.00000001141 0.67587 29.7297
327 5KSZ GCP 0.00000003302 0.64466 29.7297
328 5KUT GDP 0.0000000002153 0.72542 30.2703
329 3AQ4 GDP 0.000000000908 0.69872 30.2703
330 4YLG GDP 0.0000000005843 0.67979 30.2703
331 1ZD9 GDP 0.0000000002289 0.67841 30.2703
332 1ZJ6 G3D 0.0000000006865 0.73216 30.8108
333 1YZG GDP 0.0000000008203 0.72859 31.2849
334 2QN6 GDP 0.0000000000555 0.81099 33.3333
335 1R4A GNP 0.00000000004743 0.63753 33.3333
336 2IS6 ADP 0.00002617 0.49225 34
337 3A1S GDP 0.00000006679 0.64048 35.1351
338 2ZEJ GDP 0.00000001559 0.53228 35.3261
339 1F6B GDP 0.00000001159 0.65207 35.6757
340 1WDT GTP 0.000001651 0.52898 36.2162
341 2QTV GNP 0.00000003768 0.54514 36.7568
342 1FZQ GDP 0.0000000001308 0.77871 37.2973
343 4ZI2 GNP 0.0000000008885 0.62208 37.2973
344 4GOJ GNP 0.000000000907 0.6217 37.8378
345 5DI3 GNP 0.000000001287 0.61774 37.8378
346 5KDO GDP 0.00000004676 0.582 37.8378
347 2GJ8 ALF GDP 0.000000003419 0.55053 37.8378
348 1M2O GNP 0.00000003354 0.53517 37.8378
349 1GWN GTP 0.000000006369 0.69185 41.0811
350 1M7B GTP 0.000000002583 0.62127 41.0811
351 1SVI GDP 0.0000000000711 0.80577 42.1622
352 3GJ7 GDP 0.000000000008563 0.83469 43.2432
353 3GJ8 GDP 0.00000000001903 0.80396 43.2432
354 3GJ5 GDP 0.00000000002173 0.80131 43.2432
355 3GJX GTP 0.0000000001678 0.78195 43.2432
356 3GJ4 GDP 0.000000000007113 0.76923 43.2432
357 3M1I GTP 0.00000000008056 0.60194 43.2432
358 3WYF GTP 0.0000000001011 0.5867 43.2432
359 3WYG GTP 0.0000000001966 0.57951 43.2432
360 4DKX GDP 0.000000000001112 0.87662 43.7838
361 3GJ0 GDP 0.000000000006194 0.84134 43.7838
362 3GJ3 GDP 0.00000000001069 0.83015 43.7838
363 3RAB GNP 0.00000000003861 0.80885 43.7838
364 5UWP GNP 0.00000000005949 0.80642 43.7838
365 4HAT GNP 0.00000000006478 0.80466 43.7838
366 5UWI GNP 0.00000000006295 0.80211 43.7838
367 5UWT GNP 0.00000000006956 0.80006 43.7838
368 5BXQ GDP 0.0000000000117 0.77989 43.7838
369 5UWQ GNP 0.00000000004465 0.60867 43.7838
370 5UWJ GNP 0.00000000005104 0.60687 43.7838
371 5UWO GNP 0.0000000000552 0.60664 43.7838
372 5UWU GNP 0.00000000005355 0.60651 43.7838
373 5UWW GNP 0.00000000005672 0.60583 43.7838
374 5UWR GNP 0.00000000006029 0.60537 43.7838
375 5DHF GNP 0.00000000006556 0.60426 43.7838
376 5UWH GNP 0.00000000006856 0.604 43.7838
377 3REF GDP 0.00000000265 0.60375 43.7838
378 1IBR GNP 0.00000000007725 0.60277 43.7838
379 5UWS GNP 0.00000000007476 0.59049 43.7838
380 5DI9 GNP 0.00000000008473 0.58889 43.7838
381 1WA5 GTP 0.0000000001583 0.55044 43.7838
382 2EW1 GNP 0.000000000004456 0.8456 44.3243
383 2W2X GSP 0.00000000163 0.62939 44.8649
384 1Z0J GTP 0.00000000003377 0.61112 44.8649
385 1YVD GNP 0.00000000002141 0.82092 45.4054
386 1DS6 GDP 0.000000000003335 0.78083 45.4054
387 1A4R GNH 0.0000000003682 0.68805 45.4054
388 1A4R GDP 0.0000000002882 0.67211 45.4054
389 1NF3 GNP 0.000000002955 0.56537 45.4054
390 2NGR GDP 0.00000000009509 0.77175 45.9459
391 1GRN GDP 0.0000000001884 0.75446 45.9459
392 4DID GDP 0.00000000005249 0.75194 45.9459
393 4YC7 GNP 0.000000000725 0.73899 45.9459
394 4ITR GDP 0.0000000002526 0.67509 45.9459
395 2WKQ GTP 0.0000000009494 0.60667 45.9459
396 3E5H GNP 0.0000000002463 0.60185 45.9459
397 2NGR AF3 0.01154 0.41173 45.9459
398 2Y8E GNP 0.00000000008123 0.6113 46.3687
399 1E96 GTP 0.000000001368 0.73584 46.4865
400 1I4D GDP 0.000000000003866 0.86714 47.027
401 1HE1 GDP 0.0000000002746 0.65663 47.027
402 2FJU GSP 0.0000000004814 0.64766 47.027
403 1HE1 AF3 0.01164 0.41156 47.027
404 4D0G GTP 0.000000000002805 0.85097 47.5676
405 3Q72 GNP 0.0000000000004116 0.79377 47.5676
406 1CXZ GSP 0.000000003077 0.70985 47.5676
407 3SBD GNP 0.000000001526 0.57462 47.5676
408 1KMQ GNP 0.000000001259 0.73121 47.8261
409 1Z0F GDP 0.0000000000001031 0.90846 48.1081
410 1Z0A GDP 0.0000000000002224 0.87743 48.1081
411 3LXR GDP 0.000000000004515 0.81857 48.1081
412 4D0N GDP 0.000000000004792 0.77555 48.1081
413 2G77 GDP 0.00000000001273 0.7469 48.1081
414 4XSH GSP 0.0000000001067 0.69031 48.1081
415 5IRC GDP 0.000000005373 0.68015 48.1081
416 1Z0K GTP 0.000000000008373 0.67313 48.1081
417 5JCP GDP ALF 0.000000001045 0.67026 48.1081
418 1G4U GDP 0.0000000003935 0.66914 48.1081
419 1TX4 ALF GDP 0.0000000008047 0.61196 48.1081
420 1MH1 GNP 0.00000000007866 0.60277 48.1081
421 1YZQ GNP 0.00000000005112 0.60385 48.2353
422 2BME GNP 0.0000000000131 0.83098 48.6486
423 2D7C GTP 0.00000000003081 0.81347 48.6486
424 2GCN GDP 0.00000000007165 0.78564 48.6486
425 1RYH GNP 0.00000000002669 0.78384 48.6486
426 2GCO GNP 0.00000000007716 0.77214 48.6486
427 1Z2A GDP 0.00000000006296 0.65023 48.6486
428 2F9L GDP 0.0000000000652 0.64471 48.6486
429 4XOI GTP 0.000000001583 0.5882 48.8889
430 1Z06 GNP 0.000000000002396 0.86204 49.1892
431 2A5J GDP 0.000000000001138 0.84551 49.1892
432 3BC1 GNP 0.00000000002116 0.82116 49.1892
433 1OIX GDP 0.00000000004622 0.80518 49.1892
434 3Q85 GNP 0.000000000003563 0.77878 49.1892
435 1OIV GDP 0.000000000006102 0.84661 49.7297
436 3RWO GDP 0.00000000004845 0.80421 49.7297
437 1KY3 GDP 0.00000000001784 0.79656 49.7297
438 4U5X GNP 0.0000000002446 0.75334 49.7297
439 2HV8 GTP 0.00000000002861 0.6253 49.7297
440 4C4P GNP 0.00000000002016 0.61585 49.7297
Pocket No.: 2; Query (leader) PDB : 5TB5; Ligand: GDP; Similar sites found: 7
This union binding pocket(no: 2) in the query (biounit: 5tb5.bio2) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2DT9 THR 0.01819 0.40147 3.33333
2 3LEK BCW 0.03313 0.40055 4.57516
3 4TQK NAG 0.02512 0.40003 5.33333
4 3QKT ANP 0.0009243 0.40425 5.40541
5 4KOT CE3 0.02248 0.40327 6.79012
6 4OHY ANP 0.001202 0.40053 9.33333
7 1A8S PPI 0.02708 0.40193 17.2973
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