Receptor
PDB id Resolution Class Description Source Keywords
5THZ 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF CURJ CARBON METHYLTRANSFERASE MOOREA PRODUCENS 3L METHYLTRANSFERASE TRANSFERASE LYASE
Ref.: DOMAIN ORGANIZATION AND ACTIVE SITE ARCHITECTURE OF POLYKETIDE SYNTHASE C-METHYLTRANSFERASE. ACS CHEM. BIOL. V. 11 3319 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH B:501;
A:501;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
FLC A:502;
Invalid;
none;
submit data
189.1 C6 H5 O7 C(C(=...
GOL B:502;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5THZ 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF CURJ CARBON METHYLTRANSFERASE MOOREA PRODUCENS 3L METHYLTRANSFERASE TRANSFERASE LYASE
Ref.: DOMAIN ORGANIZATION AND ACTIVE SITE ARCHITECTURE OF POLYKETIDE SYNTHASE C-METHYLTRANSFERASE. ACS CHEM. BIOL. V. 11 3319 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 5THZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 5THZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 5THZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 197
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 SXZ 0.692308 0.916667
6 DSH 0.692308 0.914286
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 ADN 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 AMP 0.529412 0.763158
36 A 0.529412 0.763158
37 5CA 0.525773 0.712644
38 ME8 0.524752 0.8125
39 M2T 0.52439 0.821918
40 6RE 0.523256 0.824324
41 GJV 0.522727 0.813333
42 AAT 0.515789 0.863014
43 LSS 0.515152 0.696629
44 KAA 0.514852 0.727273
45 J7C 0.511364 0.835616
46 A5A 0.510417 0.697674
47 SON 0.505495 0.805195
48 SRP 0.505155 0.805195
49 5AL 0.5 0.779221
50 VMS 0.5 0.681818
51 KH3 0.5 0.866667
52 ADX 0.5 0.694118
53 CA0 0.5 0.769231
54 AMP MG 0.5 0.74359
55 AMO 0.5 0.805195
56 54H 0.5 0.681818
57 AHX 0.49505 0.753086
58 TSB 0.494949 0.689655
59 53H 0.494949 0.674157
60 G5A 0.494737 0.712644
61 A2D 0.494382 0.74359
62 ABM 0.494382 0.74359
63 ZAS 0.494253 0.808219
64 A6D 0.490196 0.759494
65 8QN 0.49 0.779221
66 GEK 0.49 0.956522
67 GAP 0.489583 0.769231
68 A3S 0.48913 0.884058
69 AN2 0.48913 0.734177
70 S4M 0.488889 0.831169
71 SRA 0.488636 0.746835
72 LAD 0.485437 0.810127
73 52H 0.484848 0.674157
74 A12 0.483516 0.759494
75 BA3 0.483516 0.74359
76 AP2 0.483516 0.759494
77 AOC 0.483146 0.842857
78 NEC 0.483146 0.788732
79 Y3J 0.481481 0.768116
80 NVA LMS 0.480392 0.696629
81 VRT 0.479167 0.861111
82 50T 0.478723 0.734177
83 5AS 0.478261 0.655556
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 AP5 0.478261 0.74359
87 A3N 0.477778 0.830986
88 YSA 0.476636 0.712644
89 XAH 0.476636 0.768293
90 0XU 0.473684 0.897059
91 WAQ 0.471154 0.807692
92 NSS 0.470588 0.712644
93 5AD 0.468354 0.791045
94 ADP MG 0.468085 0.734177
95 AU1 0.468085 0.725
96 M33 0.468085 0.734177
97 MAO 0.467391 0.797468
98 TXA 0.466667 0.759494
99 A3G 0.466667 0.871429
100 NB8 0.466667 0.775
101 3AM 0.465909 0.727273
102 DAL AMP 0.465347 0.779221
103 ATP 0.463158 0.74359
104 ADP BEF 0.463158 0.716049
105 A3T 0.463158 0.842857
106 BEF ADP 0.463158 0.716049
107 ACP 0.463158 0.746835
108 7D7 0.4625 0.785714
109 LEU LMS 0.461538 0.677778
110 APC 0.458333 0.759494
111 AQP 0.458333 0.74359
112 APR 0.458333 0.766234
113 PRX 0.458333 0.746835
114 AR6 0.458333 0.766234
115 5FA 0.458333 0.74359
116 IOT 0.456897 0.761905
117 4AD 0.456311 0.794872
118 PAJ 0.456311 0.722892
119 WSA 0.45614 0.72093
120 FA5 0.453704 0.805195
121 YAP 0.453704 0.794872
122 RBY 0.453608 0.782051
123 ADV 0.453608 0.782051
124 ADP PO3 0.453608 0.763158
125 AD9 0.453608 0.725
126 SAP 0.453608 0.728395
127 AGS 0.453608 0.728395
128 PTJ 0.45283 0.731707
129 MHZ 0.452632 0.797468
130 00A 0.451923 0.740741
131 A3P 0.451613 0.74026
132 YLP 0.451327 0.771084
133 7MD 0.45045 0.768293
134 ALF ADP 0.45 0.707317
135 ADP ALF 0.45 0.707317
136 ATP MG 0.44898 0.734177
137 2VA 0.447917 0.819444
138 OOB 0.446602 0.779221
139 ANP 0.444444 0.725
140 ACQ 0.444444 0.746835
141 TAT 0.444444 0.7375
142 P5A 0.443396 0.719101
143 7D5 0.443182 0.708861
144 ARG AMP 0.442478 0.759036
145 A1R 0.442308 0.7625
146 YLC 0.439655 0.790123
147 2AM 0.438202 0.717949
148 DLL 0.438095 0.779221
149 A22 0.436893 0.734177
150 D3Y 0.436893 0.859155
151 TYR AMP 0.436364 0.782051
152 ATF 0.435644 0.716049
153 MYR AMP 0.435185 0.746988
154 SO8 0.434343 0.808219
155 3UK 0.433962 0.769231
156 OAD 0.433962 0.769231
157 TAD 0.433628 0.765432
158 25A 0.432692 0.74359
159 ANP MG 0.431373 0.707317
160 VO4 ADP 0.431373 0.734177
161 ADP VO4 0.431373 0.734177
162 9SN 0.431193 0.731707
163 TYM 0.431034 0.805195
164 PR8 0.429907 0.8
165 ADQ 0.428571 0.746835
166 YLB 0.42735 0.771084
167 3OD 0.425926 0.769231
168 FYA 0.425926 0.779221
169 1ZZ 0.425926 0.746988
170 PPS 0.425743 0.674419
171 NVA 2AD 0.424242 0.808219
172 MAP 0.423077 0.707317
173 A2P 0.421053 0.727273
174 4YB 0.421053 0.735632
175 ADP BMA 0.420561 0.746835
176 5SV 0.419048 0.731707
177 3NZ 0.416667 0.824324
178 YLA 0.416667 0.771084
179 48N 0.413793 0.753086
180 LPA AMP 0.413793 0.768293
181 AYB 0.413223 0.761905
182 QQY 0.413043 0.696203
183 ACK 0.413043 0.710526
184 JB6 0.412844 0.7625
185 BIS 0.412844 0.719512
186 PAP 0.41 0.730769
187 OVE 0.408602 0.7125
188 4UV 0.40708 0.75
189 AMP DBH 0.40708 0.746835
190 3AD 0.406977 0.852941
191 AF3 ADP 3PG 0.40678 0.743902
192 OMR 0.40678 0.738095
193 LAQ 0.405172 0.768293
194 A A 0.40367 0.74359
195 7C5 0.403509 0.789474
196 7MC 0.403361 0.75
197 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5THZ; Ligand: SAH; Similar sites found: 282
This union binding pocket(no: 1) in the query (biounit: 5thz.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1LSS NAD 0.004943 0.40711 None
2 2UVO NDG 0.01471 0.42287 1.16959
3 2UVO NAG 0.01471 0.42287 1.16959
4 4M00 SUC 0.01774 0.41435 1.48148
5 2GK6 ADP 0.02854 0.40395 1.48148
6 3X27 TRP 0.02753 0.4065 1.49254
7 2EJU SAH 0.0002035 0.47469 1.5873
8 2YY7 NAD 0.0004097 0.40529 1.60256
9 4BWL MN9 0.03408 0.40167 1.64474
10 5E1M PRO PRO LYS ARG ILE ALA 0.000003836 0.46064 1.65975
11 5E1M SAH 0.000003836 0.46064 1.65975
12 1DJN ADP 0.003959 0.40489 1.7284
13 5XVQ SAH 0.0000001153 0.58882 1.76056
14 5DT6 GLU 0.01863 0.41535 1.87266
15 2A14 SAH 0.0000005582 0.56718 1.90114
16 2CUN 3PG 0.02538 0.4054 1.97531
17 1E5Q NDP 0.0008572 0.405 1.97531
18 1X87 NAD 0.003989 0.40475 1.97531
19 3O7W SAM 0.0000008214 0.60245 2.04082
20 3BP1 GUN 0.02825 0.4009 2.06897
21 5LOG SAH 0.00008652 0.486 2.14592
22 1ELI PYC 0.004338 0.42164 2.31362
23 3FRH SAH 0.000009297 0.51153 2.37154
24 5XVK SAH 0.0000002002 0.57911 2.46914
25 2JJQ SAH 0.00001707 0.54064 2.46914
26 4N49 SAM 0.00002055 0.50753 2.46914
27 1PS9 FAD 0.007068 0.41544 2.46914
28 1YQT ADP 0.03106 0.40466 2.46914
29 4D42 NAP 0.002772 0.44058 2.48227
30 4D42 W0I 0.002772 0.44058 2.48227
31 1F3L SAH 0.0001971 0.46186 2.49221
32 1W6F ISZ 0.0239 0.41526 2.51799
33 3VC1 GST 0.00007642 0.40388 2.5641
34 3VC1 SAH 0.00007642 0.40388 2.5641
35 5M58 SAH 0.00002114 0.51233 2.6087
36 5JJR SAH 0.000007927 0.53659 2.71605
37 4UCI SAM 0.000007751 0.53107 2.71605
38 2WHX ADP 0.009899 0.43014 2.71605
39 2WPF FAD 0.03118 0.41361 2.71605
40 4IEE AGS 0.01778 0.41038 2.71605
41 5GJC ATP 0.01906 0.40483 2.71605
42 2WPF WPF 0.04744 0.40473 2.71605
43 3H8V ATP 0.004013 0.41779 2.73973
44 1BG2 ADP 0.03994 0.40206 2.76923
45 4ONQ SFG 0.000009221 0.53371 2.80112
46 3G89 SAM 0.000006456 0.56045 2.81124
47 1T5C ADP 0.01993 0.42002 2.86533
48 4N9Z V3L 0.002792 0.46455 2.96296
49 4JJJ CBI 0.0318 0.40194 2.96296
50 2BZG SAH 0.0004039 0.46161 3.01724
51 4FRZ ADP 0.0312 0.40517 3.10881
52 5JGL SAM 0.000001694 0.57288 3.11419
53 4RDH AMP 0.00559 0.41871 3.125
54 4RDI ATP 0.005315 0.41241 3.125
55 4C4A SAH 0.00001478 0.51901 3.17919
56 3M6W SAM 0.00001181 0.54143 3.20988
57 3QOX SAH 0.00003157 0.49 3.20988
58 4J1Q NDP 0.005741 0.40435 3.23276
59 1VMK GUN 0.01673 0.41748 3.2491
60 4D79 ATP 0.005685 0.41112 3.26087
61 2REG CHT 0.0397 0.40487 3.3557
62 1WY7 SAH 0.000003735 0.53305 3.38164
63 3LKZ SFG 0.000006698 0.5338 3.42679
64 3S1S SAH 0.000002427 0.53517 3.45679
65 3ICS ADP 0.01788 0.4024 3.45679
66 1G60 SAM 0.000007235 0.53236 3.46154
67 2W58 ADP 0.005501 0.43107 3.46535
68 2F5Z FAD 0.01106 0.40875 3.5865
69 3F4F UMP 0.008775 0.40969 3.59281
70 3EVF SAH 0.00006075 0.41664 3.61011
71 3EVF GTA 0.00007537 0.40266 3.61011
72 3I53 SAH 0.0001258 0.47436 3.61446
73 4KIB SAH 0.000001571 0.5106 3.64146
74 4CVN ADP 0.02543 0.40658 3.64964
75 3ELW SAM 0.00003855 0.40427 3.66667
76 1PR9 NAP 0.0008818 0.44528 3.68852
77 3COB ADP 0.01221 0.42973 3.7037
78 3NTD FAD 0.005047 0.4188 3.7037
79 1TZD ADP 0.03674 0.40697 3.7037
80 1BC5 SAH 0.00001291 0.50574 3.71747
81 2VT3 ATP 0.01641 0.40421 3.72093
82 1ZEM NAD 0.001272 0.40844 3.81679
83 3LCC SAH 0.00001672 0.52828 3.82979
84 1JJ7 ADP 0.02564 0.41071 3.84615
85 4M73 SAH 0.00000466 0.44716 3.85757
86 4M73 M72 0.000005344 0.44324 3.85757
87 1NV8 MEQ 0.0001241 0.44105 3.87324
88 1NV8 SAM 0.0001003 0.43917 3.87324
89 2OG2 MLI 0.01622 0.40317 3.89972
90 2ZWA SAH 0.000004286 0.53058 3.95062
91 5X62 SAH 0.0001807 0.48191 3.95062
92 5KVA SAM 0.00002433 0.49942 3.95683
93 5E72 SAM 0.000004365 0.53026 4.04624
94 1IXI 2HP 0.0103 0.42948 4.04984
95 2VDV SAM 0.00003978 0.52341 4.06504
96 4AG5 ADP 0.03343 0.40297 4.08163
97 2PX8 SAH 0.000008316 0.53568 4.08922
98 5ULP KB1 0.000002213 0.52855 4.10448
99 5CUQ NSC 0.00001141 0.52352 4.11985
100 5DM1 SAH 0.00009787 0.40415 4.11985
101 3MQ2 SAH 0.00002414 0.52112 4.12844
102 4WZ6 ATP 0.02226 0.41103 4.13793
103 1O94 ADP 0.004045 0.40027 4.16667
104 2HNK SAH 0.00004433 0.49346 4.1841
105 1RJD SAM 0.000003176 0.54173 4.19162
106 2VVG ADP 0.02126 0.41968 4.28571
107 2XT3 ADP 0.02155 0.41632 4.36047
108 1I1N SAH 0.00004339 0.45904 4.42478
109 3LCV SAM 0.000002321 0.53596 4.62633
110 4TTQ ATP 0.02009 0.40369 4.65116
111 3AFN NAP 0.009826 0.4009 4.65116
112 1KYZ SAH 0.0002286 0.47732 4.65753
113 4AZT SAM 0.000003016 0.55502 4.69136
114 3HVJ 705 0.00002018 0.42517 4.69136
115 5GVR LMR 0.007652 0.43849 4.70085
116 1NW5 SAM 0.00001883 0.51449 4.70219
117 1FUT 2GP 0.01452 0.4212 4.71698
118 1DL5 SAH 0.000007047 0.49392 4.73186
119 2AOT SAH 0.000004756 0.55954 4.79452
120 1JQD HSM 0.000161 0.44137 4.79452
121 1JQD SAH 0.00007889 0.43922 4.79452
122 3TKY SAH 0.00007288 0.46268 4.8913
123 1IM8 SAI 0.000009244 0.52216 4.91803
124 3X0D SAH 0.00004986 0.49629 4.93827
125 1NFQ NAI 0.004296 0.41492 4.93827
126 2AWN ADP 0.01387 0.42799 4.98688
127 3BXO SAM 0.0000022 0.58238 5.02092
128 2WA2 SAM 0.0000126 0.48424 5.07246
129 2HK9 ATR 0.01481 0.41026 5.09091
130 1XTP SAI 0.00001546 0.52384 5.11811
131 1I0B PEL 0.008876 0.4205 5.12048
132 2CDU ADP 0.01191 0.40018 5.18518
133 1Y8Q ATP 0.002438 0.40888 5.20231
134 1WG8 SAM 0.0000112 0.51044 5.26316
135 1QAN SAH 0.0000003118 0.57763 5.32787
136 2FK8 SAM 0.00002615 0.50312 5.34591
137 3GRU AMP 0.0002137 0.45633 5.42373
138 5IFK HPA 0.0206 0.41286 5.44872
139 3OU2 SAH 0.0000001519 0.56459 5.50459
140 2F6U CIT 0.02964 0.40308 5.55556
141 1XXR MAN 0.02379 0.41307 5.59006
142 1XDS SAM 0.0002196 0.48862 5.61497
143 1O5I NAD 0.001592 0.43158 5.62249
144 2DPM SAM 0.00009037 0.47586 5.6338
145 5JE0 AZ8 0.00001779 0.45632 5.66802
146 5JE0 SAH 0.00001779 0.45632 5.66802
147 1L3I SAH 0.000004667 0.50788 5.72917
148 2XOC ADE 0.006511 0.4331 5.74713
149 1F9V ADP 0.03089 0.40541 5.76369
150 1JJV ATP 0.008332 0.43253 5.82524
151 4FZV SAM 0.000001897 0.55116 5.85774
152 2WSB NAD 0.008013 0.4121 5.90551
153 3H2B SAH 0.000001558 0.56105 5.91133
154 3DZ6 M8E 0.008406 0.40364 5.97015
155 4URG C2E 0.02155 0.40956 5.98802
156 3FZG SAM 0.00001612 0.53523 6
157 1LVG ADP 0.02876 0.40378 6.06061
158 3UCL FAD 0.002926 0.4493 6.17284
159 3UCL NAP 0.003227 0.4493 6.17284
160 3UCL CYH 0.002926 0.4493 6.17284
161 1U1J MET 0.03041 0.40156 6.17284
162 1GOJ ADP 0.01902 0.42262 6.19718
163 3P2E SAH 0.00004471 0.49331 6.22222
164 4KRG SAH 0.000002255 0.56731 6.41975
165 5MW4 5JU 0.0001449 0.41185 6.41975
166 5K7U SAM 0.0008605 0.44718 6.59026
167 3PT9 SAH 0.0000004844 0.5899 6.66667
168 3DUW SAH 0.0002916 0.4633 6.72646
169 2XKO AKG 0.03721 0.40016 6.74157
170 4LWP SAH 0.0001379 0.48212 6.79348
171 4Y2H SAH 0.0003467 0.47018 6.81818
172 4Y2H 49K 0.0005545 0.46136 6.81818
173 1V59 NAD 0.002372 0.44468 6.91358
174 1Q0S SAH 0.00002394 0.48732 6.94981
175 2BES RES 0.0135 0.40831 6.97674
176 5IL1 SAM 0.0006586 0.45228 7
177 1I9G SAM 0.000002203 0.54842 7.14286
178 3TLJ SAH 0.000007365 0.51563 7.23861
179 3WMX NAD 0.0008967 0.41354 7.26257
180 3WMX THR 0.03893 0.40582 7.26257
181 4XUC 43G 0.00007631 0.42093 7.33945
182 4XUC SAM 0.00007631 0.42093 7.33945
183 4BQS ADP 0.02023 0.40354 7.38636
184 5XLX SAH 0.00007025 0.45658 7.44681
185 4NEC SAH 0.00002696 0.52499 7.57576
186 1YXM ADE 0.0002752 0.51966 7.59076
187 2NXE SAM 0.00004745 0.50246 7.65432
188 3EGV SAH 0.0001786 0.48213 7.65432
189 1ZQ9 SAM 0.0002755 0.46891 7.7193
190 2ZIF SAM 0.00001032 0.52572 7.74411
191 2EG5 SAH 0.00002573 0.53229 7.7957
192 3C3Y SAH 0.00002448 0.50959 8.01688
193 5GWX SAM 0.00002609 0.47307 8.09859
194 5GWX SAR 0.00002609 0.47307 8.09859
195 5DX1 SFG 0.0000618 0.46511 8.14815
196 5DX8 SFG 0.0002288 0.45512 8.14815
197 5DXA SFG 0.0002444 0.45396 8.14815
198 5DWQ SFG 0.0003537 0.44164 8.14815
199 5DX0 SFG 0.0003492 0.43654 8.14815
200 3GCZ SAM 0.000003527 0.55204 8.15603
201 1G55 SAH 0.0000005415 0.58079 8.16327
202 1TJY PAV 0.02266 0.40921 8.22785
203 3GDH SAH 0.0000002225 0.56714 8.29876
204 2OBF F83 0.0000009469 0.43525 8.3045
205 2OBF SAH 0.0000009469 0.43525 8.3045
206 5E9W SAH 0.000008551 0.56199 8.33333
207 5L53 NAP 0.001416 0.42644 8.33333
208 1KPH SAH 0.00009801 0.4744 8.36237
209 2ZFU SAH 0.00008188 0.48223 8.37209
210 1U2Z SAH 0.0005446 0.43985 8.64198
211 1DCP HBI 0.04671 0.40142 8.65385
212 1M0S CIT 0.008768 0.42596 8.6758
213 2XYQ SAH 0.0003364 0.4651 9.01639
214 3BGD SAH 0.0007199 0.43493 9.1358
215 1N2X SAM 0.000006926 0.51671 9.30233
216 5FA8 SAM 0.0001439 0.46329 9.31677
217 1L1E SAH 0.00003466 0.49797 9.40767
218 3KIF GDL 0.004363 0.44645 9.43396
219 2P41 SAH 0.00001251 0.52788 9.5082
220 4II2 ATP 0.006114 0.4032 9.63855
221 3EGI ADP 0.00009538 0.53243 9.70874
222 2CH5 NDG 0.0188 0.40135 9.79827
223 1SQF SAM 0.0000008511 0.57915 9.87654
224 5DNK SAH 0.0002583 0.4969 10.1235
225 4FN4 NAD 0.0003783 0.41171 10.1235
226 3A4T SFG 0.000003281 0.53538 10.219
227 2QZ4 ADP 0.009059 0.41276 10.3053
228 5HJM MTA 0.0003239 0.46133 10.5114
229 3EVG SAH 0.000005035 0.54525 10.5455
230 5FTW SAH 0.00001858 0.50938 10.5469
231 4QTU SAM 0.000003393 0.5465 10.5769
232 4YMH SAH 0.00002279 0.50564 10.8333
233 5BW4 SAM 0.00006967 0.50047 10.8614
234 1R18 SAH 0.00001443 0.5088 10.8642
235 3DXY SAM 0.00001699 0.54767 11.0092
236 4POO SAM 0.0001544 0.45592 11.5
237 4BLW SAH 0.000287 0.43476 11.7647
238 5GM1 SAH 0.000007161 0.51612 12.0988
239 5F8F SFG 0.000007625 0.55014 12.2016
240 4DCM SAM 0.00006202 0.5084 12.2667
241 1O8B ABF 0.02832 0.40007 12.3288
242 1G6H ADP 0.0371 0.40147 12.4514
243 1P77 ATR 0.02101 0.41092 12.5
244 5L95 AMP 0.007051 0.40372 12.5
245 1AE1 NAP 0.001539 0.43504 12.8205
246 5KOK SAH 0.00001573 0.51785 12.8463
247 5KOK S9T 0.00004753 0.42726 12.8463
248 5KOK R9T 0.0001479 0.41705 12.8463
249 3FUU ADN 0.0002994 0.4628 13.2841
250 3DMH SAM 0.0000134 0.51537 13.3333
251 3DMH GMP 0.00004043 0.45732 13.3333
252 3H4S ADP 0.01878 0.41991 13.3333
253 4U00 ADP 0.02823 0.40859 13.5246
254 5N5D SAM 0.00006378 0.46228 14.1593
255 4OBW SAM 0.000004087 0.54923 14.3969
256 5MGZ SAH 0.00006733 0.49068 14.8305
257 4PIO AVI 0.00007491 0.42408 15.1703
258 4PIO SAH 0.00006983 0.42097 15.1703
259 4IWN GEK 0.00001609 0.50186 15.8025
260 2PT9 S4M 0.001534 0.41257 15.8879
261 3T7S SAM 0.000008179 0.53599 16.0448
262 2BOS GLA GAL GLC NBU 0.01665 0.41622 16.1765
263 2BOS GLA GAL GLC 0.02039 0.41024 16.1765
264 3BFV ADP 0.01344 0.40841 16.6052
265 1QZZ SAM 0.0003175 0.48111 16.7901
266 4KRI SAH 0.000002462 0.54639 17.7778
267 1Z3C SA8 0.00003607 0.44797 17.7852
268 1JG3 ADN 0.0004999 0.45755 17.8723
269 1KPG SAH 0.00006695 0.48124 18.8153
270 4PNE SAH 0.000001275 0.54651 19.2053
271 2KIN ADP 0.0356 0.40549 20
272 5E8J SAH 0.00000464 0.56718 20.4545
273 3GU3 SAH 0.00002342 0.54817 23.2394
274 4M38 SAH 0.00003012 0.50054 23.8095
275 1XCL SAH 0.0002044 0.4192 23.8298
276 3OFK SAH 0.000001273 0.55237 24.537
277 5FA5 MTA 0.0005712 0.46418 25
278 1EJ0 SAM 0.0000009909 0.57625 27.2222
279 1P1C SAH 0.0001755 0.45979 28.1407
280 1TPY SAH 0.00007079 0.48024 29.2683
281 4R6W SAH 0.00002659 0.44674 29.845
282 5MPT SAH 0.000000000001383 0.8334 44.1975
Pocket No.: 2; Query (leader) PDB : 5THZ; Ligand: SAH; Similar sites found: 16
This union binding pocket(no: 2) in the query (biounit: 5thz.bio2) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1WD4 AHR 0.02258 0.40035 1.23457
2 5MZN ADP 0.02349 0.40365 1.7284
3 3ITJ CIT 0.02812 0.41318 2.07101
4 4PX9 ADP 0.01846 0.40474 3.76712
5 2ZFI ADP 0.01845 0.40072 3.82514
6 3A4M ADP 0.02442 0.40278 3.84615
7 3NHB ADP 0.02671 0.40173 5.22876
8 1VHT BA3 0.01078 0.40421 5.50459
9 5K6A NAP 0.01073 0.40423 5.55556
10 5BWD FUM 0.0204 0.40795 5.67901
11 4JLS 3ZE 0.0215 0.40601 6.17284
12 4F8L AES 0.02835 0.40439 6.2069
13 5DJ5 GR2 0.007531 0.4242 6.36704
14 2Z48 A2G 0.02971 0.4011 6.91358
15 2CJZ PTR 0.008703 0.43035 7.21311
16 5TVF CGQ 0.01323 0.40382 8.77193
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