Receptor
PDB id Resolution Class Description Source Keywords
5TQZ 1.6 Å NON-ENZYME: OTHER FRUTAPIN COMPLEXED WITH ALPHA-D-GLUCOSE ARTOCARPUS ALTILIS PROTEIN PLANT LECTIN CARBOHYDRATE-BINDING PROTEIN
Ref.: FRUTAPIN, A LECTIN FROM ARTOCARPUS INCISA (BREADFRU CLONING, EXPRESSION AND MOLECULAR INSIGHTS. BIOSCI. REP. V. 37 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GLC A:201;
B:201;
D:201;
C:201;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
180.156 C6 H12 O6 C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5TQZ 1.6 Å NON-ENZYME: OTHER FRUTAPIN COMPLEXED WITH ALPHA-D-GLUCOSE ARTOCARPUS ALTILIS PROTEIN PLANT LECTIN CARBOHYDRATE-BINDING PROTEIN
Ref.: FRUTAPIN, A LECTIN FROM ARTOCARPUS INCISA (BREADFRU CLONING, EXPRESSION AND MOLECULAR INSIGHTS. BIOSCI. REP. V. 37 2017
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 5TQZ - GLC C6 H12 O6 C([C@@H]1[....
2 5M6O - MAN C6 H12 O6 C([C@@H]1[....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 1XXR - MAN C6 H12 O6 C([C@@H]1[....
2 5TQZ - GLC C6 H12 O6 C([C@@H]1[....
3 5M6O - MAN C6 H12 O6 C([C@@H]1[....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 2BMZ Kd = 0.2 mM XLM C12 H22 O10 CO[C@@H]1[....
2 1X1V - MMA C7 H14 O6 CO[C@@H]1[....
3 3MIT - MAN C6 H12 O6 C([C@@H]1[....
4 4PIK - MAN MAN n/a n/a
5 4PIT - MAN MAN n/a n/a
6 1C3N - MAN MAN n/a n/a
7 1C3M - MAN MAN n/a n/a
8 5TQZ - GLC C6 H12 O6 C([C@@H]1[....
9 5M6O - MAN C6 H12 O6 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GLC; Similar ligands found: 141
No: Ligand ECFP6 Tc MDL keys Tc
1 GAL 1 1
2 BMA 1 1
3 GXL 1 1
4 GLA 1 1
5 ALL 1 1
6 GLC 1 1
7 BGC 1 1
8 GIV 1 1
9 MAN 1 1
10 WOO 1 1
11 32O 0.653846 0.866667
12 RIB 0.653846 0.866667
13 FUB 0.653846 0.866667
14 Z6J 0.653846 0.866667
15 AHR 0.653846 0.866667
16 BMA BMA MAN 0.545455 0.823529
17 GLA BGC 0.511628 0.848485
18 LAK 0.511628 0.848485
19 BGC GLA 0.511628 0.848485
20 GLA BMA 0.511628 0.848485
21 MAN BMA 0.511628 0.848485
22 GLA GLC 0.511628 0.848485
23 GAL GAL 0.511628 0.848485
24 MLB 0.511628 0.848485
25 BMA GLA 0.511628 0.848485
26 BMA BMA BMA BMA BMA BMA MAN 0.5 0.823529
27 YDR 0.5 0.8
28 MAN BMA BMA BMA BMA BMA 0.5 0.823529
29 GLC GLC GLC GLC BGC 0.488889 0.848485
30 GLC GLC GLC 0.488889 0.848485
31 MAN MAN MAN 0.488889 0.848485
32 GLC GLC GLC GLC GLC BGC 0.488889 0.848485
33 BGP 0.461538 0.675
34 G6P 0.461538 0.675
35 M6P 0.461538 0.675
36 A6P 0.461538 0.675
37 M6D 0.461538 0.675
38 BG6 0.461538 0.675
39 SHG 0.457143 0.875
40 GAF 0.457143 0.875
41 G2F 0.457143 0.875
42 X6X 0.457143 0.777778
43 2FG 0.457143 0.875
44 G3F 0.457143 0.875
45 PA1 0.457143 0.777778
46 1GN 0.457143 0.777778
47 GCS 0.457143 0.777778
48 2H5 0.457143 0.875
49 LB2 0.454545 0.848485
50 BGC BMA 0.454545 0.848485
51 BGC GAL 0.454545 0.848485
52 MAL 0.454545 0.848485
53 GLC GAL 0.454545 0.848485
54 M3M 0.454545 0.848485
55 GLA GAL 0.454545 0.848485
56 MAB 0.454545 0.848485
57 GLC BGC 0.454545 0.848485
58 BMA BMA 0.454545 0.848485
59 LBT 0.454545 0.848485
60 MAL MAL 0.454545 0.823529
61 CBK 0.454545 0.848485
62 GLA GLA 0.454545 0.848485
63 MAN GLC 0.454545 0.848485
64 CBI 0.454545 0.848485
65 N9S 0.454545 0.848485
66 GAL GLC 0.454545 0.848485
67 BMA GAL 0.454545 0.848485
68 B2G 0.454545 0.848485
69 BGC GLC 0.454545 0.848485
70 LAT 0.454545 0.848485
71 GAL BGC 0.454545 0.848485
72 3MG 0.444444 0.875
73 TCB 0.444444 0.8
74 GLC SGC 0.444444 0.8
75 YIO 0.441176 0.870968
76 2GS 0.432432 0.875
77 BGC BGC 0.431818 0.848485
78 2M4 0.431818 0.848485
79 MAN MAN 0.431818 0.848485
80 AHR AHR 0.428571 0.764706
81 GLF 0.428571 0.84375
82 FUB AHR 0.428571 0.764706
83 CT3 0.416667 0.848485
84 GLC BGC GLC 0.416667 0.848485
85 MLR 0.416667 0.848485
86 GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
87 GLC GLC GLC GLC GLC 0.416667 0.848485
88 GAL FUC 0.416667 0.848485
89 BMA BMA BMA 0.416667 0.848485
90 CTR 0.416667 0.848485
91 BGC GLC GLC 0.416667 0.848485
92 BGC GLC GLC GLC GLC 0.416667 0.848485
93 MAN MAN BMA BMA BMA BMA 0.416667 0.848485
94 GLC GAL GAL 0.416667 0.848485
95 B4G 0.416667 0.848485
96 CEX 0.416667 0.848485
97 MAN BMA BMA BMA BMA 0.416667 0.848485
98 BMA BMA BMA BMA BMA 0.416667 0.848485
99 GLC BGC BGC BGC BGC BGC 0.416667 0.848485
100 CTT 0.416667 0.848485
101 GLC GLC BGC 0.416667 0.848485
102 DXI 0.416667 0.848485
103 GLC GLC BGC GLC GLC GLC GLC 0.416667 0.848485
104 BGC GLC GLC GLC 0.416667 0.848485
105 BGC BGC BGC GLC 0.416667 0.848485
106 BGC BGC BGC BGC BGC BGC 0.416667 0.848485
107 BMA BMA BMA BMA BMA BMA 0.416667 0.848485
108 MTT 0.416667 0.848485
109 BMA MAN BMA 0.416667 0.848485
110 BGC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
111 CE5 0.416667 0.848485
112 GAL GAL GAL 0.416667 0.848485
113 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.416667 0.848485
114 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
115 GLA GAL GLC 0.416667 0.848485
116 CE6 0.416667 0.848485
117 GLC BGC BGC BGC BGC 0.416667 0.848485
118 GLC BGC BGC 0.416667 0.848485
119 MAN BMA BMA 0.416667 0.848485
120 MT7 0.416667 0.848485
121 GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
122 CE8 0.416667 0.848485
123 CEY 0.416667 0.848485
124 BGC BGC BGC 0.408163 0.848485
125 BGC BGC BGC BGC BGC 0.408163 0.848485
126 GLC BGC BGC BGC BGC BGC BGC 0.408163 0.848485
127 SGC SGC BGC 0.408163 0.8
128 GLC BGC BGC BGC 0.408163 0.848485
129 BGC BGC BGC ASO BGC BGC ASO 0.408163 0.848485
130 BGC BGC BGC GLC BGC BGC 0.408163 0.848485
131 TRE 0.405405 0.848485
132 1LL 0.405405 0.771429
133 TDG 0.405405 0.771429
134 BM3 0.404762 0.7
135 NDG 0.404762 0.7
136 NAG 0.404762 0.7
137 HSQ 0.404762 0.7
138 A2G 0.404762 0.7
139 NGA 0.404762 0.7
140 FUB AHR AHR 0.4 0.764706
141 AHR AHR AHR 0.4 0.764706
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5TQZ; Ligand: GLC; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5tqz.bio1) has 10 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5TQZ; Ligand: GLC; Similar sites found: 97
This union binding pocket(no: 2) in the query (biounit: 5tqz.bio1) has 11 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4M00 SUC 0.00003992 0.52084 2.66667
2 1D4D FAD 0.01011 0.44857 2.66667
3 1QO8 FAD 0.01753 0.43434 2.66667
4 2FAV APR 0.01887 0.41196 2.66667
5 2Y6Q FAD 0.02991 0.40781 2.66667
6 2Y6Q I7T 0.04855 0.40781 2.66667
7 1Q8O MAN MMA 0.0000003558 0.63382 3.33333
8 1Q8V MAN MAN MAN 0.0000004875 0.63094 3.33333
9 2GN3 MMA 0.000000557 0.62404 3.33333
10 2GN3 MAN 0.0000005049 0.62313 3.33333
11 2PHF MAN MAN BMA MAN 0.0000009605 0.61801 3.33333
12 2GNB MAN 0.0000007044 0.61569 3.33333
13 2AR6 NAG MAN MAN MAN NAG 0.000002622 0.61433 3.33333
14 1Q8V MAN MAN 0.0000006233 0.61314 3.33333
15 2PHF MAN MAN 0.000000931 0.61276 3.33333
16 2GNM MAN 0.0000006363 0.60876 3.33333
17 2AR6 NAG MAN 0.000002359 0.60631 3.33333
18 2GND MAN 0.000000263 0.60437 3.33333
19 2PHU MAN MAN 0.0000004261 0.59356 3.33333
20 2GMM MAN MAN 0.000002849 0.57728 3.33333
21 2PHT MAN MAN MAN 0.0000005235 0.56891 3.33333
22 1Q8P MAN MMA 0.0000005525 0.54935 3.33333
23 2PHX MAN MAN MAN MAN 0.0000007206 0.54466 3.33333
24 1UKG MMA 0.00001186 0.54288 3.33333
25 2GND MAN MMA 0.0000009597 0.53997 3.33333
26 2PHW MAN MAN 0.0000009595 0.53992 3.33333
27 2PHR MAN MAN 0.000001053 0.53834 3.33333
28 1Q8S MAN MMA 0.000008676 0.53442 3.33333
29 1Q8Q MAN MMA 0.00001202 0.52751 3.33333
30 2PHR MAN MAN BMA MAN 0.0000007711 0.52695 3.33333
31 2PHX MAN MAN 0.00002068 0.51438 3.33333
32 2PHW MAN MAN MAN BMA MAN MAN MAN 0.000001005 0.50775 3.33333
33 2PHU MAN MAN MAN BMA MAN 0.000001056 0.50734 3.33333
34 2PHT MAN MAN MAN BMA MAN 0.000001198 0.50552 3.33333
35 2AUY NAG MAN MMA 0.000001785 0.48777 3.33333
36 2GMP NAG MAN 0.0003685 0.45804 3.33333
37 1M15 ADP 0.0295 0.41815 3.33333
38 1M15 ARG 0.0295 0.41815 3.33333
39 4J36 FAD 0.0218 0.41638 3.33333
40 2GCG NDP 0.02499 0.41282 3.33333
41 4J36 1HR 0.04522 0.40594 3.33333
42 4GKY MAN 0.002597 0.40051 3.33333
43 3ZYR NAG NAG BMA MAN MAN NAG NAG 0.000004184 0.41696 4
44 3ZYR ASN NAG NAG BMA MAN MAN NAG NAG 0.000004759 0.41636 4
45 3TKY SAH 0.0153 0.41473 4
46 2JFN GLU 0.008053 0.41218 4
47 5HCY 60D 0.04343 0.41193 4
48 1GQG DCD 0.02146 0.41127 4
49 2R75 01G 0.03781 0.40709 4
50 1RJD SAM 0.02795 0.40387 4
51 1CCW TAR 0.02875 0.40049 4
52 4OYA 1VE 0.02989 0.43794 4.66667
53 3LE7 ADE 0.002086 0.4228 4.66667
54 3KU0 ADE 0.006825 0.40794 4.66667
55 1KOJ PAN 0.02558 0.40505 4.66667
56 2CUN 3PG 0.002268 0.4258 5.33333
57 2BQP GLC 0.000006316 0.55364 6
58 1OFS SUC 0.00000664 0.53777 6
59 1ELI PYC 0.00533 0.4575 6
60 2X6T NAP 0.006086 0.45298 6
61 5C5H 4YB 0.008374 0.43937 6
62 3O2Q PRO THR SEP PRO SER TYR 0.01544 0.41504 6
63 2HQM FAD 0.04702 0.4122 6
64 4UP3 FAD 0.0388 0.40945 6.66667
65 1VPE ANP 0.02554 0.40527 6.66667
66 5X8G S0N 0.01841 0.43906 7.33333
67 3GDN FAD 0.01753 0.43773 7.33333
68 2BME GNP 0.02359 0.40873 7.33333
69 1WPQ NAD 0.0289 0.40318 7.33333
70 4C3Y FAD 0.04183 0.40987 8
71 1DJL NAP 0.04021 0.40709 8
72 2A92 NAI 0.02807 0.40413 8
73 4HKP TKW 0.03487 0.40339 8
74 4HAT GNP 0.007347 0.44228 8.66667
75 5UWI GNP 0.008699 0.43661 8.66667
76 3QVP FAD 0.0247 0.42747 8.66667
77 1TKB N1T 0.02905 0.41928 8.66667
78 4JWH SAH 0.02271 0.40466 8.66667
79 1ZC3 GNP 0.01313 0.42959 9.33333
80 3OVR 5SP 0.009722 0.42592 9.33333
81 1WQ1 AF3 0.004425 0.40772 9.33333
82 2F5Z FAD 0.03233 0.42159 9.375
83 4J56 FAD 0.04927 0.40012 10
84 4ZGS NAD 0.01185 0.42671 10.6667
85 4RPL FAD 0.02384 0.43937 12.6667
86 4RPL 3UC 0.02544 0.43837 12.6667
87 2YVJ NAI 0.01183 0.41675 12.6667
88 5UWT GNP 0.006715 0.44349 13.0435
89 4BV6 FAD 0.03248 0.42176 14.6667
90 1U6R ADP 0.02266 0.40383 14.6667
91 1CXZ GSP 0.03093 0.40109 15.1163
92 1BXG NAD 0.005457 0.44757 15.3333
93 5G5G FAD 0.02599 0.42186 15.3333
94 1LES GLC FRU 0.000003659 0.56022 15.3846
95 1LOB MMA 0.00004631 0.4619 15.3846
96 3QV1 NAD 0.03478 0.40262 17.0732
97 3CB2 GDP 0.01197 0.41216 26
Pocket No.: 3; Query (leader) PDB : 5TQZ; Ligand: GLC; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 5tqz.bio1) has 11 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 5TQZ; Ligand: GLC; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5tqz.bio1) has 11 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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