Receptor
PDB id Resolution Class Description Source Keywords
5V3D 1.54 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF FOSFOMYCIN RESISTANCE PROTEIN FROM KLEB PNEUMONIAE WITH BOUND FOSFOMYCIN KLEBSIELLA PNEUMONIAE FOSA FOSAKP FOSFOMYCIN GLUTATHIONE TRANSFERASE TRANSFERA
Ref.: STRUCTURE AND DYNAMICS OF FOSA-MEDIATED FOSFOMYCIN RESISTANCE IN KLEBSIELLA PNEUMONIAE AND ESCHERICHIA ANTIMICROB. AGENTS V. 61 2017 CHEMOTHER.
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
K B:202;
A:202;
Part of Protein;
Part of Protein;
none;
none;
submit data
39.098 K [K+]
MN A:204;
A:201;
Part of Protein;
Part of Protein;
none;
none;
submit data
54.938 Mn [Mn+2...
EDO B:203;
Invalid;
none;
submit data
62.068 C2 H6 O2 C(CO)...
FCN A:205;
A:203;
Valid;
Valid;
none;
none;
submit data
138.059 C3 H7 O4 P C[C@H...
PEG A:201;
Invalid;
none;
submit data
106.12 C4 H10 O3 C(COC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5V3D 1.54 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF FOSFOMYCIN RESISTANCE PROTEIN FROM KLEB PNEUMONIAE WITH BOUND FOSFOMYCIN KLEBSIELLA PNEUMONIAE FOSA FOSAKP FOSFOMYCIN GLUTATHIONE TRANSFERASE TRANSFERA
Ref.: STRUCTURE AND DYNAMICS OF FOSA-MEDIATED FOSFOMYCIN RESISTANCE IN KLEBSIELLA PNEUMONIAE AND ESCHERICHIA ANTIMICROB. AGENTS V. 61 2017 CHEMOTHER.
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 5V3D - FCN C3 H7 O4 P C[C@H]1[C@....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5V3D - FCN C3 H7 O4 P C[C@H]1[C@....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 19 families.
1 1NKI Kd ~ 0.2 uM PPF C H3 O5 P C(=O)(O)P(....
2 1LQP - FCN C3 H7 O4 P C[C@H]1[C@....
3 5V3D - FCN C3 H7 O4 P C[C@H]1[C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FCN; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 FCN 1 1
2 FM4 0.481481 0.903226
3 FV1 0.433333 0.848485
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5V3D; Ligand: FCN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5v3d.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5V3D; Ligand: FCN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5v3d.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
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