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Receptor
PDB id Resolution Class Description Source Keywords
5VLQ 2.29 Å NON-ENZYME: OTHER STRUCTURE OF THE TTLL3 GLYCYLASE XENOPUS TROPICALIS GLYCYLASE TUBULIN TTLL3 MICROTUBULE LIGASE
Ref.: CRYSTAL STRUCTURE OF TUBULIN TYROSINE LIGASE-LIKE 3 ESSENTIAL ARCHITECTURAL ELEMENTS UNIQUE TO TUBULIN MONOGLYCYLASES. PROC. NATL. ACAD. SCI. V. 114 6545 2017 U.S.A.
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP B:601;
A:601;
Valid;
Valid;
Atoms found LESS than expected: % Diff = 0;
Atoms found LESS than expected: % Diff = 0;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
SO4 A:602;
B:602;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5VLQ 2.29 Å NON-ENZYME: OTHER STRUCTURE OF THE TTLL3 GLYCYLASE XENOPUS TROPICALIS GLYCYLASE TUBULIN TTLL3 MICROTUBULE LIGASE
Ref.: CRYSTAL STRUCTURE OF TUBULIN TYROSINE LIGASE-LIKE 3 ESSENTIAL ARCHITECTURAL ELEMENTS UNIQUE TO TUBULIN MONOGLYCYLASES. PROC. NATL. ACAD. SCI. V. 114 6545 2017 U.S.A.
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 5VLQ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5VLQ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 5VLQ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5VLQ; Ligand: ANP; Similar sites found with APoc: 503
This union binding pocket(no: 1) in the query (biounit: 5vlq.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 1M0W ANP 1.01833
2 4UWH JXM 1.01868
3 4UAL 3FV 1.18845
4 2PZI AXX 1.18845
5 6EZ6 C5Z 1.18845
6 2XK9 XK9 1.24224
7 4FG8 ATP 1.26984
8 5MW8 ATP 1.27389
9 2ZV2 609 1.34228
10 5Y86 HRM 1.36054
11 3TPV ADE 1.36364
12 1O9J NAD 1.39721
13 4IOK ADP 1.43113
14 4IOK XPO 1.43113
15 4WB7 ATP 1.48148
16 5VZ0 ADP 1.52801
17 3RI1 3RH 1.59744
18 4UX9 ANP 1.64835
19 5HSA FAS 1.65913
20 5DEY 59T 1.6835
21 1QB7 ADE 1.69492
22 4FL3 ANP 1.69779
23 2AMV BIN 1.69779
24 1RE8 BD2 1.71429
25 4WB6 ATP 1.71429
26 3EFS ATP 1.71674
27 2VQD AP2 1.72414
28 4PU5 ANP 1.766
29 5YK1 ANP 1.76991
30 5TO8 7FM 1.77305
31 2VPQ ANP 1.77384
32 3PP0 03Q 1.77515
33 2GU8 796 1.78042
34 6BXI ANP 1.8018
35 4OH4 ANP 1.8018
36 3BZ3 YAM 1.81159
37 4E93 GUI 1.85676
38 6C1S EFV 1.86757
39 4JR7 GNP 1.87166
40 1Q8Y ADP 1.87668
41 1JPA ANP 1.92308
42 5JKG 6LF 1.92926
43 1VA6 P2S 1.9305
44 1VA6 ADP 1.9305
45 5NKB 8ZT 1.96078
46 4U98 ACP 1.98238
47 2QK4 ATP 1.99115
48 4WZH FMN 2.01729
49 5BV3 M7G 2.02899
50 5V49 MET 2.02952
51 1KJ8 ATP 2.04604
52 1KJ8 GAR 2.04604
53 4KS7 X4Z 2.05479
54 5USZ SKE 2.07612
55 4BHN BH9 2.09581
56 2WU6 DKI 2.09974
57 3LXK MI1 2.14067
58 3KJD 78P 2.17391
59 3PN1 IVH 2.20126
60 2YRX AMP 2.21729
61 3K5I AIR 2.23325
62 3K5I ADP 2.23325
63 3SXS PP2 2.23881
64 6G34 5ID 2.2409
65 4OUC 5ID 2.2409
66 4ORM 2V6 2.24439
67 4ORM ORO 2.24439
68 4ORM FMN 2.24439
69 5JFS 6K0 2.27273
70 5AX9 4KT 2.27273
71 4ONA UW1 2.27273
72 3C0G 3AM 2.2792
73 5A3T MMK 2.2869
74 5XVH NAP 2.28758
75 3CGD COA 2.29167
76 3CGD FAD 2.29167
77 3CGD NAD 2.29167
78 6DEF GCP 2.30179
79 4GJ3 0XP 2.31788
80 2XVD AS6 2.31788
81 5OLK DTP 2.32558
82 4X8O AP5 2.33645
83 3MVH WFE 2.33918
84 2JDR L20 2.33918
85 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 2.33918
86 3DMH SAM 2.3622
87 3DLS ADP 2.38806
88 2PVF ACP 2.39521
89 2R5T ANP 2.41287
90 6AC9 ANP 2.43243
91 4H1V GNP 2.43902
92 1Z2P ACP 2.46914
93 1Z2P I3S 2.46914
94 2YQS UD1 2.46914
95 4PIO AVI 2.47678
96 6CMJ F6J 2.49221
97 2Z7R STU 2.49221
98 4EUU BX7 2.50784
99 2PUL ACP 2.51889
100 2HGS ADP 2.53165
101 4U0I 0LI 2.53968
102 5U6C 7YS 2.53968
103 3WO0 ALA 2.54669
104 3WO0 ADP 2.54669
105 3ALN ANP 2.54669
106 2X2M X2M 2.54777
107 3HZT J60 2.56959
108 2V2V V12 2.58303
109 2Q7D ANP 2.60116
110 1T36 ADP 2.6178
111 4YMJ 4EJ 2.63158
112 5WO4 B7V 2.64901
113 3R35 4CO 2.64901
114 4BTK DTQ 2.67062
115 5VJN ADE 2.6738
116 5AOV NAP 2.67857
117 3GC8 B45 2.7027
118 1SC6 NAD 2.72277
119 5NTW 98N 2.72374
120 4GA6 AMP 2.72904
121 1TKK ALA GLU 2.73224
122 6GQM F8H 2.7439
123 4FE2 ADP 2.7451
124 4USQ FAD 2.77008
125 2YAB AMP 2.77008
126 3F8D FAD 2.78638
127 3MGB GHP 3MY 3FG GHP GHP OMY 3FG 2.82132
128 5XLX SAH 2.83688
129 3VPD ANP 2.84698
130 5QIN J2V 2.8481
131 4A4X JUP 2.86738
132 4JYD SAH 2.87356
133 5EFQ ADP 2.88184
134 4EN4 GT0 2.88462
135 4EN4 ATP 2.88462
136 4EN4 GT1 2.88462
137 1IOW PHY 2.88625
138 1IOW ADP 2.88625
139 5X8I SQZ 2.88625
140 5AE9 OKO 2.88625
141 6H3O FAD 2.88625
142 5M06 ADP 2.89855
143 1EHI ADP 2.91777
144 4USF 6UI 2.96053
145 4CYI ATP 2.96804
146 6CQF F97 3.0303
147 2CSN CKI 3.0303
148 4AU8 Z3R 3.04054
149 6E2O S0L 3.05085
150 3GRU AMP 3.05085
151 3X01 AMP 3.05344
152 2WTX UDP 3.05603
153 2WTX VDO 3.05603
154 3VOT ADP 3.05882
155 1PFY MSP 3.0853
156 5UIU 8CG 3.09598
157 5OES ADP 3.10559
158 3TXO 07U 3.11615
159 5NI5 8YB 3.125
160 4S15 4D8 3.125
161 4NST ADP 3.1339
162 3CV9 VDX 3.15534
163 5KO1 6UY 3.18021
164 1TQP ATP 3.19149
165 5N87 N66 3.19489
166 4PNI KQQ 3.20856
167 5WNL STU 3.21637
168 1YKI NFZ 3.22581
169 1YKI FMN 3.22581
170 4NFN 2KC 3.23625
171 3I0O ADP 3.24484
172 3FHI ANP 3.24675
173 5HES 032 3.25733
174 2IBY COA 3.29114
175 2IF8 ADP 3.30579
176 3O84 HTJ 3.30882
177 4H3Q ANP 3.31492
178 3O0G 3O0 3.3557
179 2H8H H8H 3.36449
180 1SZD APR 3.367
181 6ESN BWE 3.37079
182 3UG4 AHR 3.37302
183 1JQ3 AAT 3.37838
184 6F3G CJN 3.38983
185 4GYI ADP 3.39559
186 5XVG 8FX 3.41297
187 4E1Z 0MX 3.43643
188 2WMH GAL FUC 3.44234
189 3LXN MI1 3.45912
190 4Y0X ADP 3.46667
191 4PZ6 GMP 3.47395
192 6CI9 NAP 3.4749
193 4XZ3 ACP 3.47826
194 1U59 STU 3.48432
195 1ZP9 ATP 3.48837
196 3RE4 TO1 3.48837
197 1ZTH ADP 3.48837
198 5A6N U7E 3.53357
199 3RHZ UDP 3.53982
200 3KJI ADP 3.54331
201 4BFM ANP 3.59281
202 1OBD ATP 3.59477
203 3SRV S19 3.61011
204 4CSV STI 3.63636
205 5LI1 ANP 3.67232
206 2C6Q NDP 3.7037
207 5LI9 ACP 3.71429
208 4FF8 14S 3.71517
209 3IDB ANP 3.72671
210 5FA8 SAM 3.72671
211 4P5Z Q7M 3.73514
212 4OAV PO4 PO4 A A A A PO4 3.73514
213 4OAV ACP 3.73514
214 3I6I NDP 3.75723
215 4RFM 3P6 3.7594
216 1L1Q 9DA 3.76344
217 2QCS ANP 3.78007
218 6ES0 BW8 3.78549
219 3DAK ANP 3.7931
220 5VC5 96M 3.80623
221 5I35 ANP 3.81679
222 1HGX 5GP 3.82514
223 1EP2 ORO 3.83142
224 1EP2 FAD 3.83142
225 4YZN 4K5 3.83275
226 3C3N FMN 3.84615
227 1GUZ NAD 3.87097
228 4WTV ATP 3.89105
229 5AVF TAU 3.89105
230 6FL8 ADP 3.90492
231 6FL8 TIY 3.90492
232 3UDZ ADP 3.90492
233 3HAV ATP 3.90492
234 3EKK GS2 3.90879
235 3NW7 LGV 3.90879
236 3BU5 ATP 3.92157
237 5W4W 9WG 3.92749
238 4KBA 1QM 3.92749
239 5GZ9 ANP 3.93443
240 4E5N NAD 3.93939
241 4FMU 0UM 3.95683
242 2OFV 242 3.97112
243 1Y57 MPZ 3.9823
244 5ZBC FAD 3.99113
245 4K33 ACP 4
246 4NW6 2NS 4.02477
247 6C0T EE4 4.03458
248 5EW9 5VC 4.05904
249 2OO8 RAJ 4.10095
250 4OTH DRN 4.10557
251 5COU ATP 4.11765
252 5HVJ ANP 4.12698
253 4ZGS NAD 4.14508
254 2AQX ATP 4.15225
255 3KRL KRL 4.1791
256 3G5D 1N1 4.1958
257 6FNU FAD 4.22078
258 4G17 0VN 4.24242
259 5UR1 YY9 4.24448
260 3ZQ6 ADP ALF 4.24448
261 5G3U ITW 4.25532
262 5G3U FDA 4.25532
263 3UN3 G16 4.26065
264 4LXH C1E 4.33213
265 1CM8 ANP 4.35967
266 3VRY B43 4.40529
267 4CQE CQE 4.41426
268 5EKO N17 4.41426
269 2R7K AMZ 4.43213
270 2R7K ACP 4.43213
271 4ZGP ADP 4.43686
272 2HK5 1BM 4.44444
273 2BZZ AP5 4.44444
274 5OKT 9XK 4.4586
275 4QTB 38Z 4.47368
276 4IDT T28 4.49438
277 1FP6 ADP 4.49827
278 4B5P ACO 4.5
279 4DQ2 BTX 4.57317
280 3GQI ACP 4.60123
281 4KXL 6C6 4.60526
282 3GGF GVD 4.65116
283 1NY5 ADP 4.65116
284 2RG0 CBI 4.65116
285 3M2W L8I 4.68227
286 3E8N VRA 4.69208
287 3E8N ATP 4.69208
288 4H3P ANP 4.69613
289 5BVE 4VG 4.70914
290 3ETH ATP 4.78873
291 4M69 ANP 4.79233
292 4U44 3D9 4.81928
293 5FVJ ACO 4.81928
294 5TT6 ATP 4.82234
295 3C1X CKK 4.82574
296 3APT FAD 4.83871
297 4NZN ANP 4.84848
298 4NZN 2OU 4.84848
299 3F7Z 34O 4.85714
300 1V0O INR 4.86111
301 5T8O 76Z 4.87106
302 1Q1R FAD 4.87239
303 4WNP 3RJ 4.87805
304 3B2Q ATP 4.90405
305 4IEN GDP 4.90798
306 2WAT COA 4.91803
307 4YZC STU 4.93827
308 3TKI S25 4.95356
309 2PGJ N1C 4.96183
310 3VPC ADP 4.96454
311 2HY0 306 4.96894
312 6GIN IR2 4.98339
313 2JLD AG1 5
314 6A1G 9OL 5
315 3BIY 01K 5
316 1I9G SAM 5
317 2F57 23D 5.04732
318 1BW9 PPY 5.05618
319 1C1X HFA 5.07042
320 1OKE BOG 5.07614
321 4MV1 ADP 5.12821
322 5L8L ADP 5.12821
323 5VCV 1N1 5.14469
324 6AR9 3L4 5.14706
325 2Y6O 1N1 5.15464
326 4TWP AXI 5.16605
327 2F2U M77 5.22388
328 5C1P DAL DAL 5.22876
329 5C1P ADP 5.22876
330 6DNT EPZ 5.23256
331 4O4F ATP 5.24194
332 4O4F IHP 5.24194
333 5TDF ADP 5.24691
334 1E4E ADP 5.24781
335 3SLS ANP 5.26316
336 4U0W 16G 5.28455
337 1ST0 GTG 5.34125
338 1DAK ADP 5.35714
339 1DAK DPU 5.35714
340 3V8S 0HD 5.36585
341 4BAE RWX 5.36585
342 6GWR FEW 5.39683
343 2QLU ADE 5.41401
344 4WNB 4BN 5.42636
345 4X7Q 3YR 5.44872
346 2O0J ADP 5.45455
347 5EY0 GTP 5.47445
348 5EQY 5RA 5.48628
349 5HTL C2E 5.51724
350 4I6H 1C8 5.51948
351 3AKK ADP 5.53846
352 2V58 LZJ 5.56793
353 3ORQ ADP 5.57029
354 2QF7 AGS 5.60272
355 3KAL ADP 5.61122
356 2J7T 274 5.62914
357 3GF4 FAD 5.64103
358 3GF4 UPG 5.64103
359 6FW2 MTE 5.66449
360 1LO8 4CA 5.67376
361 2EV9 NAP 5.70342
362 2EV9 SKM 5.70342
363 5DH3 5BS 5.71429
364 4YNM SAM 5.75221
365 5ZAI COA 5.79151
366 4XV1 904 5.82192
367 1NBU PH2 5.88235
368 4L3L 5FI 5.92105
369 3V4S ATP 5.94315
370 3V4S ADP 5.94315
371 4JGP PYR 5.99078
372 4AT3 LTI 6.02007
373 4DC2 ADE 6.06061
374 4OCJ NDG 6.0686
375 5Y80 IRE 6.08108
376 5DXT 5H5 6.11205
377 4QMN DB8 6.12903
378 4Y93 746 6.27803
379 4I94 ANP 6.33333
380 3ZS7 ATP 6.33333
381 3GNI ATP 6.42674
382 4K81 GTP 6.43275
383 3DJV C3P 6.45161
384 4R78 AMP 6.47249
385 1BYG STU 6.47482
386 5FI4 5XV 6.50155
387 1JV1 UD1 6.53465
388 2V7O DRN 6.54762
389 4OCV ANP 6.59631
390 4G31 0WH 6.68896
391 5LVP ATP 6.75241
392 3RWP ABQ 6.75241
393 4JBI NDP 6.75676
394 3KN5 ANP 6.76923
395 4Z24 FAD 6.79117
396 3TM0 B31 6.84411
397 3TM0 ANP 6.84411
398 5TH5 7C5 6.84411
399 3W0O ADP 6.87679
400 3W0O HY0 6.87679
401 4CC6 L5Y 6.91824
402 1VJY 460 6.93069
403 2IO8 ADP 6.94669
404 4XYM A12 6.95652
405 1XJD STU 6.95652
406 6BSM E7D 6.96517
407 6BTP E8J 6.96517
408 5TA6 79D 6.98324
409 5JGA 6KC 6.98413
410 4CRL C1I 7.01754
411 5C03 AGS 7.01754
412 2QG6 NMN 7.03518
413 5HQ0 LZ9 7.14286
414 6GU6 1QK 7.14286
415 3T7V SAM 7.14286
416 4AUA 4AU 7.16612
417 4CFU 2WC 7.26073
418 1OPK P16 7.27273
419 6GUE FB8 7.28477
420 4BCM T7Z 7.30897
421 4BCN T9N 7.33333
422 2XMY CDK 7.38255
423 2PVN P63 7.38636
424 5LMK 6ZK 7.40741
425 3FC2 IBI 7.46269
426 6EMU SAM 7.61421
427 4MZQ 1VU 7.63889
428 3JVH HHV 7.65027
429 3ORK AGS 7.71704
430 1ZY5 ANP 7.92079
431 2YW2 ATP 8.01887
432 1U5R ATP 8.04598
433 3H9R TAK 8.25688
434 5EPL 5R0 PHE ALA LEU ELY 5R5 8.33333
435 2R40 20E 8.36502
436 6C7Y ADP 8.54701
437 2WEL K88 8.56269
438 2BKK ADP 8.71212
439 1KYQ NAD 8.75912
440 5YF9 NIO 8.84956
441 2GQR ADP 8.86076
442 3VSV XYP 8.93417
443 3VSV XYS 8.93417
444 1TZD ADP 9.09091
445 1GSA ADP 9.17722
446 4JLS 3ZE 9.21053
447 2GQS ADP 9.2827
448 2VN9 GVD 9.30233
449 1MZV AMP 9.3617
450 1W2D 4IP 9.43396
451 1W2D ADP 9.43396
452 4EWH T77 9.45455
453 1X87 NAD 9.61887
454 1GS5 ANP 9.68992
455 1GS5 NLG 9.68992
456 1IA9 ANP 10
457 5YW5 ADE 10.0559
458 5JZJ AN2 10.101
459 5H2U 1N1 10.1124
460 5ZCT ANP 10.1307
461 2B9J ADP 10.1983
462 2B9F ADP 10.1983
463 2B9H ADP 10.1983
464 2B9I ADP 10.1983
465 2VZ6 FEF 10.2236
466 6CZ3 FLJ 10.2273
467 5FBN 5WF 10.3321
468 4F9C 0SX 10.4167
469 1IK4 PGH 10.5263
470 1UNH IXM 10.5769
471 6FCH PRP 10.6742
472 3VPB ADP 10.7143
473 4A4Z ANP 10.8659
474 4Y8D 49J 11.4286
475 2GAG NAD 11.4286
476 2A19 ANP 11.6197
477 5L0U 660 11.9048
478 3GC0 AMP 12.1581
479 3VHE 42Q 12.5348
480 5WXH ALA ARG THR M3L GLN THR ALA 12.6984
481 5ODT ADP 13.0435
482 5QB1 F1C 13.1687
483 4HBM 0Y7 13.3333
484 2PYW ADP 13.5714
485 4ASE AV9 13.5977
486 3E5A VX6 13.6364
487 3AQV TAK 13.7681
488 3AD8 NAD 14.1414
489 1M3U KPL 14.3939
490 5UPK ANP 14.5833
491 2BPM 529 14.717
492 3KMW ATP 14.7287
493 4BCQ TJF 14.8855
494 4AG8 AXI 15.1899
495 5L0S UDP 16.6667
496 5EYK 5U5 16.9492
497 4C2W ANP 19.2308
498 2QX0 PH2 22.0126
499 4C2V YJA 22.7273
500 3ZRM ZRM 31.25
501 4NM5 ADP 37.5
502 5V22 SAH 40
503 5JLB SAH 42.8571
504 1O9U ADZ 50
Pocket No.: 2; Query (leader) PDB : 5VLQ; Ligand: ANP; Similar sites found with APoc: 109
This union binding pocket(no: 2) in the query (biounit: 5vlq.bio2) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 5U8U FAD 1.0395
2 5ZYN FAD 1.06157
3 4V24 GYR 1.34771
4 8CAT NDP 1.3834
5 2WZF UDP 1.52381
6 3ZIU LSS 1.52801
7 2WOX NDP 1.63599
8 2BVL GLC 1.65746
9 2BVL UDP 1.65746
10 2Z23 LYS LYS LYS 1.74081
11 1RPN NDP 1.79104
12 5O59 GS1 GLC GS1 1.86047
13 4ZS4 ATP 1.9544
14 5MJA 7O3 1.96721
15 5V49 8WA 2.02952
16 3TBK ANP 2.03735
17 2V0C ANZ 2.03735
18 5IH9 6BF 2.08955
19 1RQ5 CTT 2.29508
20 2AF6 BRU 2.32558
21 3GD4 FAD 2.34834
22 3GD4 NAD 2.34834
23 2YOH WMJ 2.38095
24 4YSL GSH 2.38095
25 3Q60 ATP 2.42588
26 4BV6 FAD 2.43408
27 2I7C AAT 2.4735
28 4CJX 9L9 2.50784
29 5WP5 SAH 2.64766
30 5VJN IR8 2.6738
31 2DBZ NAP 2.69461
32 4XCZ T3Q 2.71647
33 4XCZ FON 2.71647
34 5L4L NAP 2.71647
35 2YAK OSV 2.80702
36 2PID YSA 2.80899
37 1QAN SAH 2.86885
38 1VG8 GNP 2.89855
39 2BJK NAD 2.90698
40 4POO SAM 3
41 3PLS ANP 3.02013
42 6GNA FAD 3.125
43 2FB3 MET 3.23529
44 5NII FAD 3.23625
45 2OD9 A1R NCA 3.24675
46 2QQF A1R 3.24675
47 5LKT BCO 3.2872
48 3MMG GLU THR VAL ARG PHE GLN SER ASP 3.3195
49 1EZ0 NAP 3.33333
50 4IJP 1EH 3.35196
51 4N70 2HX 3.35366
52 5UIV ADP 3.52423
53 1V59 NAD 3.55649
54 4WNK 453 3.56537
55 4F4P 0SB 3.663
56 1CBK ROI 3.75
57 2Q1W NAD 3.9039
58 4L6C 0BT 3.9604
59 1K3A ACP 4.01338
60 3PVW QRX 4.05405
61 5L9O GOP 4.10448
62 4PO2 ASN ARG LEU LEU LEU THR GLY 4.25532
63 3ICR FAD 4.42177
64 3ICT FAD 4.42177
65 3ICS FAD 4.42177
66 3E7O 35F 4.44444
67 5UIJ TYD 4.44444
68 6GZD LCI 4.54545
69 3LOO B4P 4.65753
70 3MB5 SAM 4.70588
71 5AGR A52 4.74138
72 5CKS 52L 4.8433
73 1YBU APC 4.8913
74 5TDF 7A3 5.24691
75 4P5E N6P 5.26316
76 3IQE H4M 5.30035
77 3IQE F42 5.30035
78 1KUV CA5 5.31401
79 1F9A ATP 5.35714
80 3TTI KBI 5.38793
81 4Z5W TYS ILE TYS THR GLN 5.43294
82 1ERB ETR 5.46448
83 1NAA ABL 5.91497
84 1NAA 6FA 5.91497
85 1JNR FAD 6
86 6APV 3L4 6.01852
87 3BP1 GUN 6.2069
88 4LNP VAL PRO PRO PRO ARG PRO PRO PRO PRO GLU 6.55738
89 3KOX Z98 6.61157
90 4JD0 1KH 6.77291
91 6BSL EVV 6.93069
92 2Y6Q I7T 7.03518
93 4ELG 52J 7.22892
94 2X61 NGA GAL SIA 7.36434
95 1FDQ HXA 8.39695
96 4INI AMP 8.46154
97 3QVP FAD 8.48896
98 4QTU SAM 9.13461
99 4B7H NDP 9.90291
100 3KV8 FAH 10.7914
101 5W5R PYR 11.0048
102 3WBZ ATP 11.0701
103 5G1X ADP 11.1111
104 1ZQ9 SAM 11.5789
105 5LXM ADP 15.7895
106 1ZPR CB3 15.9091
107 6G96 ACO 16.4773
108 1U3G THF 18.5185
109 1KO8 6PG 19.4286
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