Receptor
PDB id Resolution Class Description Source Keywords
5W7C 2.23 Å EC: 3.1.1.77 HUMAN ACYLOXYACYL HYDROLASE (AOAH), PROTEOLYTICALLY PROCESSE MUTANT, WITH LPS HOMO SAPIENS LIPOPOLYSACCHARIDE LPS GDSL ESTERASE SAPOSIN HYDROLASE
Ref.: CRYSTAL STRUCTURE OF THE MAMMALIAN LIPOPOLYSACCHARI DETOXIFIER. PROC. NATL. ACAD. SCI. V. 115 E896 2018 U.S.A.
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FTT B:202;
C:611;
D:611;
A:202;
 Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
 submit data
244.37 C14 H28 O3 CCCCC...
CA D:601;
D:602;
C:602;
C:601;
C:603;
D:603;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
none;
none;
 submit data
40.078 Ca [Ca+2...
NAG B:201;
A:201;
D:608;
C:608;
 Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
 submit data
221.208 C8 H15 N O6 CC(=O...
DAO FTT D:609;
C:609;
 Valid;
Valid;
 none;
none;
 submit data
425.674 n/a O=C(O...
NAG NAG E:1;
H:1;
F:1;
G:1;
 Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
 submit data
408.404 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5W7C 2.23 Å EC: 3.1.1.77 HUMAN ACYLOXYACYL HYDROLASE (AOAH), PROTEOLYTICALLY PROCESSE MUTANT, WITH LPS HOMO SAPIENS LIPOPOLYSACCHARIDE LPS GDSL ESTERASE SAPOSIN HYDROLASE
Ref.: CRYSTAL STRUCTURE OF THE MAMMALIAN LIPOPOLYSACCHARI DETOXIFIER. PROC. NATL. ACAD. SCI. V. 115 E896 2018 U.S.A.
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5W78 - MYR C14 H28 O2 CCCCCCCCCC....
2 5W7C - DAO FTT n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5W78 - MYR C14 H28 O2 CCCCCCCCCC....
2 5W7C - DAO FTT n/a n/a
3 5W7B - MYR C14 H28 O2 CCCCCCCCCC....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5W78 - MYR C14 H28 O2 CCCCCCCCCC....
2 5W7C - DAO FTT n/a n/a
3 5W7B - MYR C14 H28 O2 CCCCCCCCCC....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: DAO FTT; Similar ligands found: 15
No: Ligand ECFP6 Tc MDL keys Tc
1 DAO FTT 1 1
2 2JT 0.56 0.647059
3 G2A 0.56 0.647059
4 TGL 0.509091 0.8
5 56S 0.5 0.740741
6 FAW 0.474576 0.75
7 1EM 0.474576 0.75
8 L2C 0.474576 0.75
9 DDR 0.474576 0.75
10 DGA 0.474576 0.75
11 PX8 0.439394 0.609756
12 PX2 0.439394 0.609756
13 8ND 0.424242 0.6
14 PA8 0.424242 0.609756
15 LBR 0.424242 0.676471
Similar Ligands (3D)
Ligand no: 1; Ligand: DAO FTT; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5W7C; Ligand: DAO FTT; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5w7c.bio2) has 21 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback