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Receptor
PDB id Resolution Class Description Source Keywords
5X62 2.2 Å EC: 2.1.1.22 CRYSTAL STRUCTURE OF A CARNOSINE N-METHYLTRANSFERASE BOUND B SACCHAROMYCES CEREVISIAE (STRAIN ATCC S288C) METHYLTRANSFERASE SAM ROSSMANN FOLD TRANSFERASE
Ref.: SUBSTRATE RECOGNITION MECHANISM OF THE PUTATIVE YEA CARNOSINE N-METHYLTRANSFERASE ACS CHEM. BIOL. V. 12 2164 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NA B:502;
Part of Protein;
none;
submit data
22.99 Na [Na+]
SAH B:501;
A:501;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5X62 2.2 Å EC: 2.1.1.22 CRYSTAL STRUCTURE OF A CARNOSINE N-METHYLTRANSFERASE BOUND B SACCHAROMYCES CEREVISIAE (STRAIN ATCC S288C) METHYLTRANSFERASE SAM ROSSMANN FOLD TRANSFERASE
Ref.: SUBSTRATE RECOGNITION MECHANISM OF THE PUTATIVE YEA CARNOSINE N-METHYLTRANSFERASE ACS CHEM. BIOL. V. 12 2164 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5X62 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5X62 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5X62 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5X62; Ligand: SAH; Similar sites found with APoc: 786
This union binding pocket(no: 1) in the query (biounit: 5x62.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 1MAI I3P None
2 3GWZ SAH 0.813008
3 3GXO SAH 0.813008
4 3OND NAD 0.985222
5 3OND ADN 0.985222
6 1I2B UPG 0.990099
7 1I2B NAD 0.990099
8 1I2B USQ 0.990099
9 1S7G APR 1.18577
10 1S7G NAD 1.18577
11 4BJZ FAD 1.23153
12 4BJZ P3A 1.23153
13 2Z3Y F2N 1.23153
14 2VVL FAD 1.23153
15 2VVM FAD 1.23153
16 3TKY SAH 1.3587
17 4G5H NAP 1.37741
18 4G5H UD7 1.37741
19 5JGL SAM 1.38408
20 3A4T SFG 1.45985
21 5MPT SAH 1.47783
22 6B3A SAM 1.47783
23 4X9M FAD 1.47783
24 3X0V FAD 1.47783
25 5MZI FYK 1.47783
26 5MZI FAD 1.47783
27 3GMB FAD 1.47783
28 3NTA FAD 1.47783
29 5Y77 FAD 1.47783
30 4RPL FAD 1.50376
31 4RPL 3UC 1.50376
32 1GY8 NAD 1.51134
33 3CTY FAD 1.5674
34 4LWP SAH 1.63043
35 4KIB SAH 1.68067
36 6B92 SAH 1.70068
37 2RAB NAD 1.72414
38 2RAB FAD 1.72414
39 6DEN TP9 1.72414
40 6DEN FAD 1.72414
41 6DEN G8A 1.72414
42 5JJR SAH 1.72414
43 4M52 FAD 1.72414
44 4YNU FAD 1.72414
45 4YNU LGC 1.72414
46 2YVF FAD 1.72414
47 2YVF NAD 1.72414
48 4M52 M52 1.72414
49 1MO9 FAD 1.72414
50 4MOP 2H5 1.72414
51 1MO9 KPC 1.72414
52 3TKA SAM 1.72911
53 5U19 SAH 1.75953
54 5U19 827 1.75953
55 3LCV SAM 1.77936
56 6FDF SAH 1.79641
57 1ELI PYC 1.79949
58 5K0A FAD 1.81818
59 3KLJ FAD 1.81818
60 3RFV NAI 1.87266
61 3RFV 15L 1.87266
62 5Z3I ADE 1.88679
63 1ZK7 FAD 1.97044
64 1T9D P25 1.97044
65 5WKC FAD 1.97044
66 1T9D PYD 1.97044
67 1T9D 1MM 1.97044
68 1YBH FAD 1.97044
69 1T9D FAD 1.97044
70 4KGD TDP 1.97044
71 4KGD FAD 1.97044
72 5BUK FAD 1.97044
73 3CGD FAD 1.97044
74 3CGD COA 1.97044
75 3CGD NAD 1.97044
76 3EYA FAD 1.97044
77 3CGB FAD 1.97044
78 2R4J FAD 1.97044
79 2R4J 13P 1.97044
80 3SSO SAH 1.97044
81 2RGJ FAD 1.99005
82 6GFK SAH 1.99203
83 4YAC NAI 2.0202
84 5TWB FAD 2.03488
85 5FUB SAH 2.07715
86 4NTC FAD 2.08955
87 3CH6 311 2.0979
88 3CH6 NAP 2.0979
89 3C3Y SAH 2.1097
90 2WK1 SAH 2.12766
91 3ZV6 NAD 2.13523
92 3ZV6 4HB 2.13523
93 1ZBQ NAD 2.14067
94 3HB5 NAP 2.14067
95 3EF0 ALF 2.15054
96 4K26 SFF 2.17391
97 4K26 NDP 2.17391
98 6ECT SAM 2.18069
99 3LKZ SFG 2.18069
100 2A92 NAI 2.18069
101 1GZ6 NAI 2.19436
102 1DL5 SAH 2.2082
103 1PJS NAD 2.21675
104 1SQF SAM 2.21675
105 5W7R SAH 2.21675
106 1COY FAD 2.21675
107 5W7R 9Z7 2.21675
108 1COY AND 2.21675
109 2XVE FAD 2.21675
110 5I39 FAD 2.21675
111 2IID FAD 2.21675
112 2IID PHE 2.21675
113 3ICT FAD 2.21675
114 1EU1 MGD 2.21675
115 1D4D FAD 2.21675
116 2V3V MGD 2.21675
117 3L9W GSH 2.21675
118 4Z24 FAD 2.21675
119 4J36 FAD 2.21675
120 4J36 1HR 2.21675
121 3ICR FAD 2.21675
122 3ICS FAD 2.21675
123 1E1M NAP 2.21675
124 1E1M FAD 2.21675
125 4DSG UDP 2.21675
126 4DSG FAD 2.21675
127 5GSN NAP 2.21675
128 5GSN FAD 2.21675
129 4FWE FAD 2.21675
130 3L9W AMP 2.21675
131 1R6B ADP 2.21675
132 5MZN ADP 2.21675
133 5KMS NAD 2.22222
134 5KMS FAD 2.22222
135 4ITU NAI 2.23048
136 4ITU 1HS 2.23048
137 1IY8 NAD 2.24719
138 2A14 SAH 2.28137
139 3GFB NAD 2.28571
140 1U1I NAD 2.29592
141 2O07 SPD 2.30263
142 2O07 MTA 2.30263
143 5E72 SAM 2.31214
144 4PNE SAH 2.31788
145 1H0H MGD 2.33645
146 2EFJ SAH 2.34375
147 3FPF TNA 2.34899
148 3FPF MTA 2.34899
149 5F8F SFG 2.38727
150 1WY7 SAH 2.41546
151 2EG5 SAH 2.41935
152 4RDI ATP 2.43056
153 4RDH AMP 2.43056
154 4MO2 FDA 2.44565
155 4MO2 FAD 2.44565
156 1ZQ9 SAM 2.45614
157 2Q7V FAD 2.46154
158 4KRG SAH 2.46305
159 1FEC FAD 2.46305
160 4JDR FAD 2.46305
161 4D5G FAD 2.46305
162 4D5G TPP 2.46305
163 2CDU FAD 2.46305
164 1FL2 FAD 2.46305
165 6ER9 NAP 2.46305
166 6ER9 FAD 2.46305
167 3G5S FAD 2.46305
168 1H82 FAD 2.46305
169 1H82 GZZ 2.46305
170 1Q8O MAN MMA 2.46305
171 4EIP FAD 2.46305
172 3P9C SAH 2.47253
173 1UAY ADN 2.47934
174 2Y6Q I7T 2.51256
175 2Y6Q FAD 2.51256
176 3EVF GTA 2.52708
177 3EVF SAH 2.52708
178 2CBZ ATP 2.53165
179 4D79 ATP 2.53623
180 6EQS BV8 2.54545
181 5E9W SAH 2.5641
182 5E8J SAH 2.5641
183 3RIY NAD 2.5641
184 6GAR FAD 2.5788
185 3QWI CUE 2.59259
186 3QWI NAP 2.59259
187 2PX8 SAH 2.60223
188 5ULP KB1 2.61194
189 2AWN ADP 2.62467
190 5EEH SAH 2.65957
191 5EEH P9P 2.65957
192 3ITJ FAD 2.66272
193 5ZW3 SAH 2.66667
194 3RKR NAP 2.67176
195 1XDS SAM 2.6738
196 1QZZ SAM 2.6738
197 3DUW SAH 2.69058
198 1RJD SAM 2.69461
199 5FA5 MTA 2.70936
200 5BVA FAD 2.70936
201 2ZWA SAH 2.70936
202 3AXB PRO 2.70936
203 3AXB FAD 2.70936
204 5JAQ NAI 2.70936
205 4NTD FAD 2.70936
206 3S5W FAD 2.70936
207 4YKG FAD 2.70936
208 4YKG NAD 2.70936
209 2IVD FAD 2.70936
210 5TS5 FAD 2.70936
211 1REO FAD 2.70936
212 5YB7 ORN 2.70936
213 5YB7 FAD 2.70936
214 1RSG FAD 2.70936
215 5MBX SP5 2.70936
216 5MBX FAD 2.70936
217 2NXE SAM 2.75591
218 3FPZ AHZ 2.76074
219 3VSE SAH 2.76382
220 4BLW AMP 2.76817
221 4BLW SAH 2.76817
222 1EJ0 SAM 2.77778
223 1WG8 SAM 2.80702
224 4E70 N7I 2.83505
225 3GCZ SAM 2.83688
226 5XLX SAH 2.83688
227 1FP2 SAH 2.84091
228 1FP2 HMO 2.84091
229 5HJM MTA 2.84091
230 6ECU SAH 2.8481
231 6ECW SAH 2.85714
232 1IM8 SAI 2.86885
233 1EDO NAP 2.86885
234 3LST SAH 2.87356
235 2Q0L FAD 2.89389
236 5O42 BGC 2.91971
237 5O42 9JW 2.91971
238 5O42 NAD 2.91971
239 4X7Y SAH 2.91971
240 5MLR NAP 2.91971
241 5MLR GRQ 2.91971
242 4JNA FAD 2.94118
243 5TUK FAD 2.94118
244 4RVG TYD 2.95567
245 4RVG SAM 2.95567
246 1GET FAD 2.95567
247 1GET NAP 2.95567
248 1V5F FAD 2.95567
249 1V5F TPP 2.95567
250 1LVL FAD 2.95567
251 5EB4 FAD 2.95567
252 6F7L FAD 2.95567
253 1Q1R FAD 2.95567
254 1LVL NAD 2.95567
255 2JB2 FAD 2.95567
256 2JB2 PHE 2.95567
257 2RGO FAD 2.95567
258 1G8K MGD 2.95567
259 1YY5 FAD 2.95567
260 2IS6 ADP 2.95567
261 3WQQ NDP 2.95567
262 3WQQ IB3 2.95567
263 5A3B APR 2.9703
264 1RLZ NAD 2.98103
265 5DF1 58X 2.98913
266 5DF1 NAP 2.98913
267 5CUQ NSC 2.99625
268 1I8T FAD 2.99728
269 4POO SAM 3
270 1XHL NDP 3.0303
271 4CQM NAP 3.06513
272 1J1R ADE 3.06513
273 3A4M ADP 3.07692
274 3H8V ATP 3.08219
275 1W5F G2P 3.11615
276 5N0J FAD 3.1339
277 3MB5 SAM 3.13725
278 2FK8 SAM 3.14465
279 1RP0 AHZ 3.16901
280 5YJI SAH 3.16901
281 5YJI 8WO 3.16901
282 3X0D SAH 3.20197
283 3SQP FAD 3.20197
284 4AP3 FAD 3.20197
285 4AP3 NAP 3.20197
286 6FP4 FAD 3.20197
287 6FP4 E1T 3.20197
288 3GDN HBX 3.20197
289 3GDN FAD 3.20197
290 1YQZ FAD 3.20197
291 2DKH 3HB 3.20197
292 3IHG FAD 3.20197
293 2DKH FAD 3.20197
294 5BRT FAD 3.20197
295 5BRT CH9 3.20197
296 4K5S PM0 3.20197
297 4K5S FAD 3.20197
298 1UP7 NAD 3.20197
299 3QJ4 FAD 3.21637
300 5XNC MTA 3.2345
301 3VYW SAM 3.24675
302 2WA2 SAM 3.26087
303 3QV1 NAD 3.2641
304 5Z2L NDP 3.26531
305 2P41 SAH 3.27869
306 4Z0H NAD 3.29341
307 3LZW NAP 3.31325
308 3LZW FAD 3.31325
309 3CIF NAD 3.34262
310 3CIF G3H 3.34262
311 1ZGA SAH 3.36134
312 1JQ3 AAT 3.37838
313 5DLY SAH 3.38346
314 5DLY 5D7 3.38346
315 3C6K SPD 3.41207
316 3C6K MTA 3.41207
317 3NYC IAR 3.41207
318 3NYC FAD 3.41207
319 1MRH FMC 3.42205
320 3LAD FAD 3.44828
321 2GV8 FAD 3.44828
322 1VQW FAD 3.44828
323 2GVC FAD 3.44828
324 2XVF FAD 3.44828
325 4EMI NAD 3.44828
326 4EMI FAD 3.44828
327 2YG3 FAD 3.44828
328 4EMJ FAD 3.44828
329 1Q9I FAD 3.44828
330 1Q9I TEO 3.44828
331 1OC2 TDX 3.44828
332 1OC2 NAD 3.44828
333 5XWV NDP 3.44828
334 5XWV 8H6 3.44828
335 2GN4 NDP 3.48837
336 2GN4 UD1 3.48837
337 1G55 SAH 3.49854
338 6FHO FAD 3.50877
339 1GEG NAD 3.51562
340 3OZ2 FAD 3.52645
341 5KVA SAM 3.59712
342 2Q1W NAD 3.6036
343 1BDB NAD 3.61011
344 3GJ0 GDP 3.61991
345 3EVG SAH 3.63636
346 4ONQ SFG 3.64146
347 3GEG NAD 3.64372
348 3ELW GP3 3.66667
349 3ELW SAM 3.66667
350 2YVJ FAD 3.66972
351 3G2O SAM 3.67893
352 4A6D SAM 3.68272
353 5HXI 5HN 3.69393
354 5HXI FAD 3.69393
355 6D6Y SAH 3.69458
356 2OEM 1AE 3.69458
357 2C31 ADP 3.69458
358 2C31 TZD 3.69458
359 5NMX FAD 3.69458
360 5NMX NAP 3.69458
361 2NPX FAD 3.69458
362 2NPX NAD 3.69458
363 6AIN FAD 3.69458
364 6GKV SAH 3.7037
365 2ZIF SAM 3.7037
366 1F3L SAH 3.73832
367 3O7W SAM 3.7415
368 1XHC FAD 3.81471
369 5EZ7 FAD 3.82653
370 1KYZ SAH 3.83562
371 1KYZ FER 3.83562
372 5LOG SAH 3.86266
373 4X60 3XV 3.87597
374 4X60 SFG 3.87597
375 2PWY SAH 3.87597
376 2BZG SAH 3.87931
377 1G0N PHH 3.88693
378 1G0N NDP 3.88693
379 1EFV FAD 3.92157
380 1EFV AMP 3.92157
381 4GQB 0XU 3.92465
382 6EL3 NAP 3.93701
383 2PZM UDP 3.93939
384 2PZM NAD 3.93939
385 3NDJ JHZ 3.94089
386 3NDJ SAH 3.94089
387 3PT9 SAH 3.94089
388 2WPF FAD 3.94089
389 2WPF WPF 3.94089
390 5HSA FAS 3.94089
391 4D7E FAD 3.94089
392 4RSL FAD 3.94089
393 4D04 FAD 3.94089
394 4D04 NAP 3.94089
395 3LXD FAD 3.94089
396 5JCM FAD 3.94089
397 5JCM NAD 3.94089
398 5JCM ISD 3.94089
399 4DXD GDP 3.94089
400 3NT6 FAD 3.94089
401 5THY SAH 3.95062
402 5THZ SAH 3.95062
403 5ICE SAH 3.97727
404 5ICE 2H4 3.97727
405 4Y30 SAH 3.9886
406 4Y30 49L 3.9886
407 2GDZ NAD 4.11985
408 5TUF FAD 4.15648
409 5TUF TDC 4.15648
410 5U8U FAD 4.18719
411 3QOX SAH 4.18719
412 5VN0 NAI 4.18719
413 5VN0 FAD 4.18719
414 4OPC PGT 4.18719
415 4OPC FDA 4.18719
416 1X87 NAD 4.18719
417 3NTD FAD 4.18719
418 1P3D UMA 4.21053
419 1XCL SAH 4.25532
420 5MIT FAD 4.28135
421 5MIT NAP 4.28135
422 5KOK SAH 4.28212
423 5KOK R9T 4.28212
424 5KOK S9T 4.28212
425 5UR0 NAD 4.29799
426 4D0N GDP 4.32432
427 4FN4 NAD 4.33071
428 1Y63 ADP 4.34783
429 1JJV ATP 4.36893
430 4M37 SAH 4.37318
431 4M38 SAH 4.37318
432 5N5D SAM 4.42478
433 3NKS FAD 4.4335
434 2A8X FAD 4.4335
435 3NJ4 AFX 4.4335
436 3NJ4 NAD 4.4335
437 2ZXI FAD 4.4335
438 2ZJ1 ARJ 4.4335
439 2ZJ1 NAD 4.4335
440 2W58 ADP 4.45545
441 4ZCC NAI 4.46429
442 4ZCC FAD 4.46429
443 2EJU SAH 4.49735
444 3I53 SAH 4.51807
445 1L1E SAH 4.52962
446 3WV8 ATP 4.58716
447 3BGD SAH 4.61538
448 3BGD PM6 4.61538
449 4TQG NDP 4.64396
450 3OID NDP 4.65116
451 2NVK FAD 4.6798
452 4REP FAD 4.6798
453 4HA6 FAD 4.6798
454 5WGR FAD 4.6798
455 6H3O FAD 4.6798
456 5KOX RFP 4.6798
457 5KOX FAD 4.6798
458 4UCI SAM 4.6798
459 6C5B SAH 4.69208
460 2Q46 NAP 4.74308
461 3GRU AMP 4.74576
462 6C8R SAH 4.74934
463 6C8R EQV 4.74934
464 1JQD HSM 4.79452
465 1JQD SAH 4.79452
466 4NBU NAI 4.8
467 1DJL NAP 4.83092
468 2UYQ SAM 4.83871
469 5DM1 SAH 4.86891
470 5DM1 5D7 4.86891
471 1VL8 NAP 4.86891
472 1KPH SAH 4.87805
473 1KPG SAH 4.87805
474 4BUZ OAD 4.87805
475 4BUZ OCZ 4.87805
476 4BUZ NAD 4.87805
477 1YC5 NCA 4.87805
478 3MAG SAH 4.88599
479 5OJ7 AR6 4.8951
480 4KRI SAH 4.92611
481 1GPE FAD 4.92611
482 4MIG G3F 4.92611
483 3S1S SAH 4.92611
484 3E1T FAD 4.92611
485 1NM5 NAD 4.92611
486 1NM5 NAP 4.92611
487 1V8B NAD 4.92611
488 3F8D FAD 4.95356
489 3U4C NDP 4.98221
490 2PT9 2MH 4.98442
491 2PT9 S4M 4.98442
492 1P1C SAH 5.02513
493 4M73 SAH 5.04451
494 4M73 M72 5.04451
495 3MCT SAH 5.05051
496 5MW4 5JU 5.08982
497 5F2K OCA 5.16304
498 5F2K SAH 5.16304
499 5WP5 SAH 5.17241
500 3A25 SAM 5.17241
501 6F97 FAD 5.17241
502 4XQC 13D 5.17241
503 4XQC NAD 5.17241
504 5G3U FDA 5.17241
505 3UCL CYH 5.17241
506 3UCL FAD 5.17241
507 3UCL NAP 5.17241
508 4LHD GLY 5.17241
509 5G3U ITW 5.17241
510 3T7S SAM 5.22388
511 4Y9D NAI 5.2459
512 4USQ FAD 5.26316
513 4PIO AVI 5.26316
514 4PIO SAH 5.26316
515 2C5A GDC 5.27704
516 2C5A NAD 5.27704
517 3GU3 SAH 5.28169
518 2DTX BMA 5.30303
519 2BD0 NAP 5.32787
520 5GM1 SAH 5.38721
521 1Q0S SAH 5.40541
522 1DSS NAD 5.40541
523 5WP4 SAH 5.41872
524 5DNK SAH 5.41872
525 1BZL GCG 5.41872
526 1BZL FAD 5.41872
527 4R6W PC 5.42636
528 4R6W SAH 5.42636
529 5W7M SAH 5.44872
530 2DFV NAD 5.4755
531 3MQ2 SAH 5.50459
532 3FUU ADN 5.53506
533 2OBF SAH 5.53633
534 2OBF F83 5.53633
535 4YJK URA 5.55556
536 1PNO NAP 5.55556
537 2Q1S NAI 5.57029
538 1TPY SAH 5.57491
539 5BW4 SAM 5.61798
540 1UDB NAD 5.6213
541 1UDB UFG 5.6213
542 3G89 SAM 5.62249
543 5J60 FAD 5.625
544 5YJF 8WO 5.6338
545 5YJF SAH 5.6338
546 2IV2 MGD 5.66502
547 2QA1 FAD 5.66502
548 6GAS FAD 5.74018
549 2OOR TXP 5.74713
550 3WGT FAD 5.76369
551 3WGT QSC 5.76369
552 4L2I FAD 5.78035
553 3HDY GDU 5.79345
554 3HDY FDA 5.79345
555 3HDY FAD 5.79345
556 1V59 FAD 5.85774
557 1V59 NAD 5.85774
558 5UFN SAH 5.88235
559 4B63 ORN 5.91133
560 4B63 FAD 5.91133
561 4B63 NAP 5.91133
562 5FJN BE2 5.91133
563 5FJN FAD 5.91133
564 4N49 SAM 5.91133
565 4KP7 NAP 5.91133
566 4KP7 1UQ 5.91133
567 4AT0 FAD 5.91133
568 1JG3 ADN 5.95745
569 3KU0 ADE 5.9761
570 5JCA FAD 5.98592
571 5JCA NDP 5.98592
572 3DMH SAM 6.03675
573 3DMH GMP 6.03675
574 4URF NAD 6.04839
575 4UP3 FAD 6.05096
576 1O97 FAD 6.06061
577 1O97 AMP 6.06061
578 4IWN GEK 6.11354
579 3GF4 FAD 6.15385
580 3GF4 UPG 6.15385
581 1U2Z SAH 6.15764
582 6F3M NAD 6.15764
583 2GAG NAD 6.17284
584 2GAG FAD 6.17284
585 2GAG FOA 6.17284
586 3AD8 NAD 6.18812
587 3AD8 FAD 6.18812
588 3AD8 PYC 6.18812
589 5FA8 SAM 6.21118
590 3P2E SAH 6.22222
591 5L95 AMP 6.25
592 2HNK SAH 6.27615
593 6HOY TSN 6.29139
594 6HOY AR6 6.29139
595 3FRH SAH 6.32411
596 4DMG SAM 6.36132
597 4AZW SAM 6.36943
598 2BRY FAD 6.40394
599 4TXI FAD 6.40394
600 3AYI HCI 6.40394
601 3AYI FAD 6.40394
602 4IV9 FAD 6.40394
603 5ODQ FAD 6.40394
604 3ZG6 APR 6.41892
605 4XUC 43G 6.42202
606 4XUC SAM 6.42202
607 1M2K APR 6.4257
608 4HSU FAD 6.45161
609 4GUT FAD 6.45161
610 2CUL FAD 6.46552
611 1G16 GDP 6.47059
612 2PXX SAH 6.51163
613 5ERG SAM 6.52742
614 5OJI ISN 6.53846
615 5OJI NAP 6.53846
616 1PR9 NAP 6.55738
617 3D3W NAP 6.55738
618 4RDN 6MD 6.58683
619 1VE3 SAM 6.60793
620 3GDH SAH 6.639
621 2JHP SAH 6.65025
622 4EUE NAI 6.65025
623 3Q9T FAY 6.65025
624 1Z3C SA8 6.71141
625 5MGZ SAH 6.77966
626 2YX1 SFG 6.84524
627 1NW5 SAM 6.89655
628 1PN0 FAD 6.89655
629 1PN0 IPH 6.89655
630 4YAG NAI 6.92042
631 3AB1 FAD 6.94444
632 4LH7 1X8 7.12074
633 3UOY NAP 7.14286
634 3UOY FAD 7.14286
635 1XKQ NDP 7.14286
636 1GTE FAD 7.14286
637 1QHH ATP 7.18563
638 3LCC SAH 7.23404
639 3TLJ SAH 7.23861
640 4CVN ADP 7.29927
641 2VDV SAM 7.31707
642 1NVM NAD 7.37179
643 3H2B SAH 7.38916
644 5M67 NAD 7.38916
645 5M67 3D1 7.38916
646 5M67 ADE 7.38916
647 5M58 SAH 7.3913
648 3TNF GNP 7.47126
649 1XTP SAI 7.48031
650 2VPY MGD 7.50988
651 5O74 GDP 7.61421
652 4C3Y ANB 7.63547
653 4C3Y FAD 7.63547
654 3WDM ADN 7.66284
655 3EGI ADP 7.76699
656 1Y8Q ATP 7.80347
657 1L3I SAH 7.8125
658 1E6E FAD 7.8125
659 4C4A SAH 7.88177
660 5E1M SAH 7.88382
661 5E1M PRO PRO LYS ARG ILE ALA 7.88382
662 5BJX NAD 7.9235
663 5BJX UDP 7.9235
664 4FZV SAM 7.94979
665 2V6G NAP 7.96703
666 4DCM SAM 8
667 6ARJ BW4 8.02292
668 6ARJ SAH 8.02292
669 5DXA SFG 8.02292
670 5DX1 SFG 8.02292
671 5DX8 SFG 8.02292
672 5DWQ SFG 8.02292
673 5DX0 SFG 8.02292
674 5ZHO A2G GLA FUC 8.02469
675 1JA9 NDP 8.0292
676 3UVD MB3 8.06452
677 3ZNN 4WL 8.06916
678 3ZNN FAD 8.06916
679 2DPM SAM 8.09859
680 5EJ2 NAD 8.11688
681 2I7C AAT 8.12721
682 3QFA FAD 8.12808
683 1BC5 SAH 8.17844
684 2AOT SAH 8.21918
685 4YUW S4M 8.22368
686 4YUW 4JU 8.22368
687 3O03 NAP 8.24742
688 3OU2 SAH 8.25688
689 4NEC SAH 8.33333
690 2HMT NAI 8.33333
691 4YRY FAD 8.33333
692 4YRY NAD 8.33333
693 1NAA 6FA 8.37438
694 1NAA ABL 8.37438
695 1KYQ NAD 8.39416
696 1NV8 MEQ 8.4507
697 1NV8 SAM 8.4507
698 3A27 SAM 8.45588
699 4OBW SAM 8.56031
700 1LSS NAD 8.57143
701 3HVJ 705 8.59729
702 3GJ4 GDP 8.59729
703 5FWA J7C 8.62069
704 1RRC ADP 8.63787
705 3GJ8 GDP 8.69565
706 2B4R NAD 8.69565
707 2B4R AES 8.69565
708 3JWH SAH 8.75576
709 1G60 SAM 8.84615
710 5X68 FAD 8.95141
711 1N2X SAM 8.9701
712 3VC1 SAH 8.97436
713 3VC1 GST 8.97436
714 3FZG SAM 9
715 1QAN SAH 9.01639
716 3SJ7 NDP 9.12698
717 1FP1 SAH 9.13978
718 2XYQ SAH 9.31034
719 3GD4 NAD 9.60591
720 3GD4 FAD 9.60591
721 6CI9 NAP 9.65251
722 4USR FAD 9.69529
723 2ZFU SAH 9.76744
724 2HQM FAD 9.85222
725 4BV6 FAD 9.85222
726 1QO8 FAD 9.85222
727 5GWX SAR 9.85915
728 5GWX SAM 9.85915
729 1P72 ADP 9.88024
730 3BJE URA 10.0287
731 4RUS NAG 10.084
732 2RH4 EMO 10.1083
733 5FTW SAH 10.1562
734 1I1N SAH 10.177
735 1WA5 GTP 10.2273
736 1UWK URO 10.3448
737 1UWK NAD 10.3448
738 3U31 NAD 10.3448
739 5JE0 SAH 10.5263
740 5JE0 AZ8 10.5263
741 3IIJ ADP 10.5556
742 2WSB NAD 10.6299
743 6DUB SAH 10.8108
744 5YEC ATP 10.9244
745 6F9Q NAD 11.0294
746 2XVM SAH 11.0553
747 4QTU SAM 11.0577
748 1I9G SAM 11.0714
749 1DMR PGD 11.0837
750 6BQ6 TER 11.1782
751 5BSZ SAH 11.2
752 3GJ7 GDP 11.2245
753 1RYI FAD 11.5183
754 1RYI GOA 11.5183
755 4YSX FAD 11.5385
756 4CNK FAD 11.7647
757 1R18 SAH 11.8943
758 3DXY SAM 11.9266
759 5YRG BGC GLC 11.9718
760 2Q28 ADP 12.069
761 1XSE NDP 12.2034
762 5T67 JHZ 12.5616
763 5T67 SAH 12.5616
764 6F5Z SAH 13.1148
765 3OFK SAH 13.4259
766 1DIG NAP 14.0523
767 5W7K SAH 14.1026
768 4YMH SAH 14.1667
769 3CBG SAH 14.2241
770 4TM3 FAD 14.2857
771 3Q87 SAM 15.2
772 5OC1 FAD 15.5172
773 4II2 ATP 15.6627
774 2EWM NAD 15.6627
775 4J56 FAD 15.7895
776 2JJQ SAH 16.2562
777 2F5Z FAD 16.9951
778 3BXO SAM 17.1548
779 5J5Z FAD 17.2414
780 1NJR XYL 17.2535
781 3CH5 GDP 17.3077
782 3RNM FAD 17.734
783 3PFG SAM 22.0532
784 3PFG TLO 22.0532
785 3GJ5 GDP 23.5294
786 4YMZ 13P 27.49
Pocket No.: 2; Query (leader) PDB : 5X62; Ligand: SAH; Similar sites found with APoc: 19
This union binding pocket(no: 2) in the query (biounit: 5x62.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 2GK6 ADP 1.47783
2 1OBB NAD 1.47783
3 1R6D DAU 1.48368
4 1R6D NAD 1.48368
5 4HSE ADP 1.76322
6 2IZ1 ATR 1.97044
7 5GSN MMZ 2.21675
8 5TTJ FAD 2.21675
9 2JK0 ASP 5.23077
10 1Z0J GTP 5.29412
11 2QE0 NAP 6.15764
12 4GUS FAD 6.45161
13 3NGL NAP 7.24638
14 5BXQ GDP 8.33333
15 4TTQ ATP 8.37209
16 1KQF MGD 11.0599
17 5YRJ BGC GLC 11.9718
18 4X9D U5P 12.6761
19 1VG9 GDP 16.2162
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