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Receptor
PDB id Resolution Class Description Source Keywords
5Z21 2.3 Å EC: 1.1.1.28 THE TERNARY STRUCTURE OF D-LACTATE DEHYDROGENASE FROM FUSOBA NUCLEATUM WITH NADH AND OXAMATE FUSOBACTERIUM NUCLEATUM SUBSP. NUCLEAT(STRAIN ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131) TERNARY COMPLEX ROSSMANN FOLD DEHYDROGENASE NADH BINDINGOXIDOREDUCTASE
Ref.: STRUCTURAL BASIS OF SEQUENTIAL ALLOSTERIC TRANSITIO TETRAMERIC D-LACTATE DEHYDROGENASES FROM THREE GRAM BACTERIA. BIOCHEMISTRY V. 57 5388 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
OXM A:402;
D:402;
C:402;
B:402;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
89.05 C2 H3 N O3 C(=O)...
NAI D:401;
A:401;
C:401;
B:401;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
665.441 C21 H29 N7 O14 P2 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5Z21 2.3 Å EC: 1.1.1.28 THE TERNARY STRUCTURE OF D-LACTATE DEHYDROGENASE FROM FUSOBA NUCLEATUM WITH NADH AND OXAMATE FUSOBACTERIUM NUCLEATUM SUBSP. NUCLEAT(STRAIN ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131) TERNARY COMPLEX ROSSMANN FOLD DEHYDROGENASE NADH BINDINGOXIDOREDUCTASE
Ref.: STRUCTURAL BASIS OF SEQUENTIAL ALLOSTERIC TRANSITIO TETRAMERIC D-LACTATE DEHYDROGENASES FROM THREE GRAM BACTERIA. BIOCHEMISTRY V. 57 5388 2018
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 5Z21 - NAI C21 H29 N7 O14 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 5Z21 - NAI C21 H29 N7 O14 P2 c1nc(c2c(n....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1J49 - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
2 5Z21 - NAI C21 H29 N7 O14 P2 c1nc(c2c(n....
3 5Z20 - OXM C2 H3 N O3 C(=O)(C(=O....
4 4ZGS - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: OXM; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 OXM 1 1
2 MLM 0.466667 0.607143
3 PYM 0.461538 0.636364
4 HGY 0.4 0.904762
Ligand no: 2; Ligand: NAI; Similar ligands found: 262
No: Ligand ECFP6 Tc MDL keys Tc
1 NAI 1 1
2 0WD 0.814815 0.986842
3 NDP 0.803738 0.986842
4 AP0 0.743119 0.961039
5 NMN AMP PO4 0.704348 0.960526
6 NAX 0.663717 0.961538
7 A2D 0.659574 0.933333
8 80F 0.65 0.925926
9 6V0 0.649123 0.986842
10 TXE 0.62931 0.948052
11 BA3 0.628866 0.933333
12 AP5 0.622449 0.933333
13 B4P 0.622449 0.933333
14 TXD 0.62069 0.923077
15 AR6 0.613861 0.907895
16 APR 0.613861 0.907895
17 EAD 0.609375 0.961538
18 SAP 0.607843 0.8625
19 AGS 0.607843 0.8625
20 ADP 0.606061 0.907895
21 HEJ 0.60396 0.907895
22 50T 0.60396 0.871795
23 ATP 0.60396 0.907895
24 AN2 0.6 0.896104
25 AT4 0.6 0.873418
26 A22 0.598131 0.921053
27 AQP 0.598039 0.907895
28 5FA 0.598039 0.907895
29 M33 0.594059 0.896104
30 CA0 0.594059 0.909091
31 AD9 0.592233 0.884615
32 NAJ PZO 0.592 0.935897
33 P1H 0.590909 0.9375
34 ACP 0.588235 0.884615
35 4AD 0.587156 0.886076
36 A1R 0.587156 0.851852
37 PRX 0.582524 0.8375
38 ANP 0.580952 0.884615
39 3OD 0.580357 0.909091
40 SRP 0.579439 0.873418
41 ADX 0.578431 0.821429
42 OAD 0.576577 0.909091
43 5AL 0.575472 0.896104
44 NAJ PYZ 0.573643 0.890244
45 A3R 0.572727 0.851852
46 ADJ 0.569106 0.890244
47 UP5 0.566667 0.960526
48 ACQ 0.566038 0.884615
49 9X8 0.5625 0.8625
50 A 0.561224 0.881579
51 AMP 0.561224 0.881579
52 ATF 0.555556 0.873418
53 6YZ 0.550459 0.884615
54 8QN 0.54955 0.896104
55 25L 0.547826 0.921053
56 4TC 0.544715 0.935897
57 AMO 0.544643 0.897436
58 PAJ 0.544643 0.853659
59 ADQ 0.544643 0.909091
60 ABM 0.544554 0.858974
61 NPW 0.544 0.949367
62 WAQ 0.54386 0.851852
63 LAD 0.54386 0.831325
64 PR8 0.54386 0.821429
65 DQV 0.541667 0.946667
66 DG1 0.541353 0.986842
67 1DG 0.541353 0.986842
68 00A 0.539823 0.875
69 NZQ 0.539683 0.974026
70 BIS 0.53913 0.851852
71 1ZZ 0.53913 0.811765
72 APC 0.537736 0.873418
73 OMR 0.536585 0.823529
74 OOB 0.535714 0.921053
75 25A 0.535714 0.907895
76 5SV 0.535714 0.797619
77 3UK 0.535088 0.909091
78 A12 0.533981 0.873418
79 AP2 0.533981 0.873418
80 B5V 0.530435 0.897436
81 DND 0.528455 0.922078
82 NXX 0.528455 0.922078
83 CNA 0.527559 0.922078
84 DLL 0.526316 0.921053
85 AHX 0.526316 0.864198
86 PTJ 0.525862 0.841463
87 ME8 0.525862 0.811765
88 FYA 0.525862 0.871795
89 NB8 0.525862 0.864198
90 B5M 0.525424 0.886076
91 YAP 0.525424 0.886076
92 SRA 0.524752 0.8375
93 SON 0.52381 0.873418
94 TAT 0.522936 0.873418
95 T99 0.522936 0.873418
96 ADP VO4 0.522523 0.871795
97 VO4 ADP 0.522523 0.871795
98 48N 0.520325 0.864198
99 YLP 0.520325 0.793103
100 YLB 0.52 0.793103
101 AU1 0.518868 0.884615
102 ADP PO3 0.518519 0.881579
103 9SN 0.516949 0.864198
104 DAL AMP 0.513274 0.871795
105 TXA 0.512821 0.897436
106 B5Y 0.512605 0.886076
107 FA5 0.512605 0.897436
108 GAP 0.509091 0.860759
109 9ZA 0.508772 0.851852
110 9ZD 0.508772 0.851852
111 4UU 0.508197 0.960526
112 YLC 0.507937 0.833333
113 T5A 0.507812 0.925926
114 RBY 0.504587 0.873418
115 ADV 0.504587 0.873418
116 TYR AMP 0.504132 0.8625
117 4UW 0.504 0.924051
118 TXP 0.503876 0.911392
119 ALF ADP 0.5 0.817073
120 G3A 0.5 0.8875
121 F2R 0.5 0.813953
122 TYM 0.5 0.897436
123 ADP ALF 0.5 0.817073
124 LAQ 0.5 0.811765
125 COD 0.496183 0.786517
126 139 0.496124 0.9125
127 YLA 0.496124 0.813953
128 G5P 0.495935 0.8875
129 AFH 0.495935 0.853659
130 XAH 0.495868 0.811765
131 BT5 0.492424 0.784091
132 AYB 0.492308 0.784091
133 A4P 0.492188 0.880952
134 GTA 0.491935 0.855422
135 4UV 0.491803 0.960526
136 A2R 0.491228 0.896104
137 MAP 0.486957 0.8625
138 NAD 0.484848 0.921053
139 XNP 0.484848 0.936709
140 UPA 0.484375 0.948052
141 7MD 0.483871 0.833333
142 ARG AMP 0.483871 0.781609
143 MYR AMP 0.483333 0.790698
144 NA7 0.483051 0.873418
145 YLY 0.477941 0.784091
146 ATR 0.477477 0.881579
147 AOC 0.47619 0.792208
148 ATP A A A 0.47541 0.894737
149 BTX 0.473684 0.793103
150 5AS 0.472222 0.736264
151 GA7 0.472 0.873418
152 LMS 0.471154 0.77907
153 NAQ 0.471014 0.864198
154 ADP BMA 0.470588 0.884615
155 N0B 0.467626 0.835294
156 A A 0.466667 0.883117
157 A3D 0.466667 0.909091
158 NJP 0.466165 0.910256
159 IOT 0.465649 0.784091
160 AF3 ADP 3PG 0.465116 0.809524
161 PAP 0.464286 0.894737
162 NAE 0.463768 0.886076
163 7MC 0.461538 0.813953
164 DZD 0.459259 0.876543
165 ZID 0.457143 0.909091
166 TAD 0.456693 0.853659
167 2A5 0.455357 0.8375
168 62F 0.453947 0.833333
169 AHZ 0.453125 0.790698
170 FB0 0.452055 0.76087
171 JB6 0.45082 0.851852
172 ITT 0.45045 0.857143
173 7D4 0.45045 0.825
174 LPA AMP 0.449612 0.790698
175 G5A 0.447368 0.755556
176 LEU LMS 0.446281 0.731183
177 M24 0.446043 0.843373
178 AVV 0.445378 0.841463
179 NDC 0.442177 0.864198
180 NSS 0.441667 0.775281
181 4TA 0.441176 0.890244
182 VMS 0.440678 0.764045
183 54H 0.440678 0.764045
184 7D3 0.440367 0.825
185 5CD 0.44 0.753247
186 PPS 0.439655 0.8
187 XYA 0.438776 0.789474
188 ADN 0.438776 0.789474
189 RAB 0.438776 0.789474
190 NDE 0.438356 0.897436
191 NVA LMS 0.438017 0.731183
192 AR6 AR6 0.4375 0.883117
193 TSB 0.436975 0.793103
194 53H 0.436975 0.755556
195 8X1 0.436975 0.731183
196 DTA 0.436893 0.759494
197 A2P 0.436364 0.868421
198 A3P 0.436364 0.881579
199 A5A 0.435897 0.781609
200 FNK 0.435065 0.840909
201 HFD 0.434783 0.8625
202 ODP 0.433824 0.924051
203 SFG 0.433628 0.725
204 Z5A 0.433566 0.858824
205 6FA 0.433333 0.835294
206 SSA 0.432203 0.775281
207 J7C 0.431193 0.702381
208 DTP 0.431034 0.825
209 P5A 0.430894 0.723404
210 AMP NAD 0.430657 0.896104
211 5N5 0.43 0.766234
212 DSZ 0.429752 0.775281
213 LSS 0.429752 0.73913
214 52H 0.428571 0.755556
215 SFD 0.427632 0.731959
216 9K8 0.427419 0.712766
217 6AD 0.42735 0.831325
218 EP4 0.427184 0.707317
219 FDA 0.426667 0.870588
220 ARU 0.42623 0.788235
221 6RE 0.425926 0.694118
222 A4D 0.425743 0.766234
223 5CA 0.425 0.775281
224 3DH 0.424528 0.725
225 AV2 0.423729 0.835443
226 AMP DBH 0.421875 0.860759
227 U A 0.421429 0.923077
228 DAT 0.421053 0.825
229 5X8 0.421053 0.7375
230 GSU 0.419355 0.755556
231 MTA 0.419048 0.725
232 3AT 0.418803 0.883117
233 ETB 0.41844 0.786517
234 DCA 0.41844 0.777778
235 FAD 0.418301 0.845238
236 FAS 0.418301 0.845238
237 A3N 0.418182 0.759494
238 F2N 0.417178 0.850575
239 7D5 0.415094 0.8
240 A U 0.414815 0.910256
241 YSA 0.414062 0.775281
242 0T1 0.412587 0.777778
243 A C A C 0.411348 0.8875
244 2AM 0.411215 0.857143
245 9JJ 0.409938 0.855422
246 M2T 0.409524 0.690476
247 KAA 0.408 0.731183
248 7C5 0.407692 0.790123
249 3AM 0.407407 0.844156
250 NAP 0.406897 0.909091
251 8PZ 0.40625 0.795455
252 PUA 0.405594 0.9
253 FAY 0.405063 0.855422
254 P5F 0.404908 0.83908
255 EEM 0.403361 0.670455
256 COA 0.402778 0.777778
257 RFL 0.402516 0.816092
258 GJV 0.401786 0.686047
259 SA8 0.401709 0.686047
260 U A C C 0.401408 0.898734
261 WSA 0.4 0.784091
262 G A A A 0.4 0.841463
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5Z21; Ligand: NAI; Similar sites found with APoc: 1065
This union binding pocket(no: 1) in the query (biounit: 5z21.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 5N2I NAP None
2 1Z0N BCD None
3 3RGQ 5P5 None
4 5WGR FAD 1.11732
5 3PUN FUC GAL NDG FUC 1.26582
6 5G3U FDA 1.39665
7 5G3U ITW 1.39665
8 1E1M FAD 1.39665
9 1E1M NAP 1.39665
10 4B63 ORN 1.39665
11 4B63 NAP 1.39665
12 4B63 FAD 1.39665
13 3QVP FAD 1.39665
14 3GF4 FAD 1.39665
15 3VSE SAH 1.39665
16 3GF4 UPG 1.39665
17 1BXK NAD 1.40845
18 5DOZ NDP 1.47929
19 4ZCC FAD 1.4881
20 4ZCC NAI 1.4881
21 2Q7V FAD 1.53846
22 4O1M NAD 1.5873
23 2O07 SPD 1.64474
24 2O07 MTA 1.64474
25 2WPF WPF 1.67598
26 2WPF FAD 1.67598
27 4R5M NAP 1.67598
28 1BZL FAD 1.67598
29 1BZL GCG 1.67598
30 3SQP FAD 1.67598
31 4R5M 4NO 1.67598
32 2JB2 PHE 1.67598
33 2JB2 FAD 1.67598
34 4RPL FAD 1.67598
35 4RPL 3UC 1.67598
36 3S5W NAP 1.67598
37 3FWN ATR 1.67598
38 3S5W FAD 1.67598
39 2IVD FAD 1.67598
40 4D7E FAD 1.67598
41 1QMG APX 1.67598
42 3ZV6 4HB 1.77936
43 3ZV6 NAD 1.77936
44 4GLL NAD 1.78042
45 1HDG NAD 1.80723
46 3VGL BGC 1.86916
47 1DLJ NAI 1.95531
48 1D1T NAD 1.95531
49 1DLJ UGA 1.95531
50 1UP7 NAD 1.95531
51 2NVK NAP 1.95531
52 3L4S NAD 1.95531
53 2GV8 FAD 1.95531
54 4BJZ P3A 1.95531
55 4BJZ FAD 1.95531
56 3L4S 3PG 1.95531
57 2VVL FAD 1.95531
58 2VVM FAD 1.95531
59 2R4J FAD 1.95531
60 2R4J 13P 1.95531
61 3GDN FAD 1.95531
62 3GDN HBX 1.95531
63 5EZ7 FAD 1.95531
64 2NVK FAD 1.95531
65 5TTJ FAD 1.95531
66 2GVC FAD 1.95531
67 1VQW FAD 1.95531
68 4DMG SAM 1.95531
69 4PIV NDP 1.95531
70 2GV8 NDP 1.95531
71 3HDY FAD 1.95531
72 3HDY GDU 1.95531
73 3HDY FDA 1.95531
74 3G5S FAD 1.95531
75 1WVG APR 1.95531
76 6F7L FAD 1.95531
77 4FXQ G9L 1.95652
78 1RKX NAD 1.96078
79 4Y9D NAI 1.96721
80 5N0J FAD 1.9943
81 2EWM NAD 2.00803
82 3ZNN FAD 2.01729
83 3ZNN 4WL 2.01729
84 4W6Z 8ID 2.01729
85 1LLU NAD 2.04678
86 2BKA NDP 2.06612
87 1WP4 NDP 2.07612
88 2CVZ NDP 2.07612
89 3H4V NAP 2.08333
90 3H4V DVP 2.08333
91 1VDC FAD 2.1021
92 5K4W NAI 2.18069
93 5K4W THR 2.18069
94 1LDN NAD 2.21519
95 3AY6 NAI 2.23048
96 1Q0H NDP 2.23464
97 1Q0H FOM 2.23464
98 2CDU FAD 2.23464
99 5GSN FAD 2.23464
100 5GSN NAP 2.23464
101 1O0S NAI 2.23464
102 1H82 GZZ 2.23464
103 1H82 FAD 2.23464
104 5GSN MMZ 2.23464
105 1U8X NAD 2.23464
106 1KEW NAD 2.23464
107 1D4D FAD 2.23464
108 4G5H NAP 2.23464
109 4G5H UD7 2.23464
110 5JCM NAD 2.23464
111 5JCM ISD 2.23464
112 5JCM FAD 2.23464
113 4HXY NDP 2.23464
114 2CDU ADP 2.23464
115 4X9M FAD 2.23464
116 5XWV NDP 2.23464
117 4MIG G3F 2.23464
118 6FP4 E1T 2.23464
119 5XWV 8H6 2.23464
120 6FP4 FAD 2.23464
121 4MO2 FDA 2.23464
122 6C4M NAP 2.23464
123 1LVL NAD 2.23464
124 4MO2 FAD 2.23464
125 5EB4 FAD 2.23464
126 1KEW TYD 2.23464
127 1PGP 6PG 2.23464
128 1LVL FAD 2.23464
129 4Y1B NAP 2.23464
130 2Q1S NAI 2.23464
131 4USQ FAD 2.23464
132 5KKA 6V0 2.24359
133 2Q0L NAP 2.2508
134 2Q0L FAD 2.2508
135 5NM7 GLY 2.25564
136 5AYV KPL 2.26537
137 5AYV NAP 2.26537
138 2DTX BMA 2.27273
139 4YUW S4M 2.30263
140 4YUW 4JU 2.30263
141 2ZAT NAP 2.30769
142 6DNT NAD 2.32558
143 3AFN NAP 2.32558
144 4NBW NAD 2.33463
145 3WLE NAD 2.34604
146 5OJL TXP 2.34899
147 1XSE NDP 2.37288
148 1RPN NDP 2.38806
149 5A96 GTP 2.40964
150 5K0A FAD 2.42424
151 1LUA NAP 2.43902
152 2CVQ NDP 2.44648
153 3CH6 311 2.44755
154 3CH6 NAP 2.44755
155 5GZ6 NDP 2.45399
156 5GZ6 7C3 2.45399
157 3FPZ AHZ 2.45399
158 3U4C NDP 2.4911
159 1F06 NDP 2.5
160 1F06 2NP 2.5
161 1XKQ NDP 2.5
162 1LTH NAD 2.50784
163 3CTY FAD 2.50784
164 2IZ1 ATR 2.51397
165 1GQ2 NAP 2.51397
166 3KLJ FAD 2.51397
167 5OC1 FAD 2.51397
168 3WMX NAD 2.51397
169 2VZ0 D64 2.51397
170 2VZ0 NAP 2.51397
171 5JDI NAP 2.51397
172 4CM9 NAP 2.51397
173 4CLR NAP 2.51397
174 3BMO NAP 2.51397
175 3BMN NAP 2.51397
176 5JDC NAP 2.51397
177 3JQF NAP 2.51397
178 3JQA NAP 2.51397
179 4CM4 NAP 2.51397
180 5JCJ NAP 2.51397
181 3BMQ NAP 2.51397
182 4CM8 NAP 2.51397
183 3JQ9 NAP 2.51397
184 4CMI NAP 2.51397
185 3JQG NAP 2.51397
186 5K6A NAP 2.51397
187 5YAP NAI 2.51397
188 3NT6 FAD 2.51397
189 5MLR NAP 2.51397
190 5MLR GRQ 2.51397
191 5YAP 8S0 2.51397
192 5E4R NAP 2.51397
193 3JQ7 NAP 2.51397
194 4CME NAP 2.51397
195 4CLO NAP 2.51397
196 5JWC FAD 2.51397
197 3V1U NAD 2.51397
198 3NTA FAD 2.51397
199 3JQ8 NAP 2.51397
200 1H9A NAP 2.51397
201 3JQB NAP 2.51397
202 6FHO FAD 2.51397
203 5L4S NAP 2.51572
204 5L4S 6KX 2.51572
205 2RH4 EMO 2.52708
206 2ZL4 ALA ALA ALA ALA 2.55102
207 1SB8 UD2 2.55682
208 1SB8 NAD 2.55682
209 5X20 NAD 2.5641
210 3VPH NAD 2.58065
211 3VPH OXM 2.58065
212 5EJ2 NAD 2.5974
213 5TWB FAD 2.61628
214 4XDZ NDP 2.62391
215 5X9D 80F 2.63158
216 1R6D NAD 2.67062
217 1R6D DAU 2.67062
218 1U7T TDT 2.68199
219 1U7T NAD 2.68199
220 3FPF TNA 2.68456
221 3FPF MTA 2.68456
222 3CMC NAD 2.69461
223 1JQ3 AAT 2.7027
224 4EA7 JB2 2.72727
225 4EA7 COA 2.72727
226 5YSS NAD 2.73438
227 1LDM NAD 2.73556
228 2DKN NAI 2.7451
229 3ICC NAP 2.7451
230 5OCM NAP 2.74914
231 3RJ5 NAD 2.75591
232 4RDH AMP 2.77778
233 4RDI ATP 2.77778
234 1N5D NDP 2.77778
235 2VT3 ATP 2.7907
236 1GZ4 ATP 2.7933
237 5U8U FAD 2.7933
238 4J36 1HR 2.7933
239 4J36 FAD 2.7933
240 5BJX NAD 2.7933
241 5BJX UDP 2.7933
242 1XHC FAD 2.7933
243 5TS5 FAD 2.7933
244 1RYD NDP 2.7933
245 5GUD 2IT 2.7933
246 3OZ2 FAD 2.7933
247 5GUD NDP 2.7933
248 6F97 FAD 2.7933
249 5XWC 8GL 2.7933
250 5XWC NAP 2.7933
251 5XWC 2IT 2.7933
252 3NTD FAD 2.7933
253 5GUD CIT 2.7933
254 1UWK URO 2.7933
255 1UWK NAD 2.7933
256 1T26 NAI 2.79503
257 1T26 GBD 2.79503
258 1E7S NAP 2.80374
259 1BXG NAD 2.80899
260 1BW9 NAD 2.80899
261 1C1X NAD 2.8169
262 4REP FAD 2.82828
263 1JAY NAP 2.83019
264 2BD0 NAP 2.86885
265 1OC2 NAD 2.87356
266 1OC2 TDX 2.87356
267 1EK6 NAI 2.87356
268 1EK6 UPG 2.87356
269 5GWT SIN 2.8777
270 5GWT NAD 2.8777
271 1ORR NAD 2.88184
272 5ZBC FAD 2.88248
273 5CGE 51F 2.88809
274 4D79 ATP 2.89855
275 3EGI ADP 2.91262
276 5XVH NAP 2.94118
277 4NTD FAD 2.94118
278 3ITJ FAD 2.95858
279 3ITJ CIT 2.95858
280 2RI1 GLP 2.97872
281 5JE8 NAD 2.98013
282 1W73 NAP 2.98013
283 1W8D NAP 2.98013
284 1W6U NAP 2.98013
285 4PLG NAI 2.99401
286 4PLG OXM 2.99401
287 5NUF NAD 3.01205
288 5NUE NAD 3.01205
289 4FWE FAD 3.01508
290 5Z2F NAP 3.01887
291 4YAC NAI 3.0303
292 1XHL NDP 3.0303
293 5GT9 NAP 3.04183
294 4FK7 P34 3.05677
295 5MIT NAP 3.0581
296 5MIT FAD 3.0581
297 1MUU NAD 3.07263
298 5CAE SIN 3.07263
299 5Y77 FAD 3.07263
300 5CAE COA 3.07263
301 5MZI FYK 3.07263
302 5MZI FAD 3.07263
303 2YVF FAD 3.07263
304 2YVF NAD 3.07263
305 4RSL FAD 3.07263
306 3AXB PRO 3.07263
307 6C4N NAP 3.07263
308 3AXB FAD 3.07263
309 2C7G FAD 3.07263
310 2C7G ODP 3.07263
311 1RSG FAD 3.07263
312 1PS9 FAD 3.07263
313 1YY5 FAD 3.07263
314 5HSA FAS 3.07263
315 2DKH 3HB 3.07263
316 1OBB NAD 3.07263
317 3NKS FAD 3.07263
318 1PS9 NAP 3.07263
319 3DAG FEG 3.07263
320 1M2W NAD 3.07263
321 2RGH FAD 3.07263
322 4USR FAD 3.07263
323 2DKH FAD 3.07263
324 5UAO FAD 3.07263
325 2J5V PCA 3.07263
326 2AWN ADP 3.07263
327 3Q9T FAY 3.07263
328 3KO8 NAD 3.07263
329 1LJ8 NAD 3.07263
330 1N1G BCP 3.07263
331 3C3Y SAH 3.07263
332 2ZXI FAD 3.07263
333 4A0S NAP 3.07263
334 1OAA OAA 3.0888
335 3A28 NAD 3.10078
336 5ZW3 SAH 3.11111
337 6GNA FAD 3.125
338 2QZZ EMF 3.14465
339 2QZZ NAP 3.14465
340 2WSB NAD 3.14961
341 1VKF CIT 3.19149
342 1HYE NAP 3.19489
343 2YYY NAP 3.207
344 3WV8 ATP 3.21101
345 3QJ4 FAD 3.21637
346 3V0H I3P 3.24484
347 4K26 SFF 3.26087
348 4K26 NDP 3.26087
349 3QV1 NAD 3.2641
350 4NTC FAD 3.28358
351 1KYQ NAD 3.28467
352 1JA9 NDP 3.28467
353 1YJQ NAP 3.30033
354 6F9Q NAD 3.30882
355 4RF2 NAP 3.30882
356 5T9E NAP 3.32103
357 1PZG A3D 3.32326
358 1V59 NAD 3.35196
359 4RQU NAD 3.35196
360 5VN0 NAI 3.35196
361 4EDF UPG 3.35196
362 1V59 FAD 3.35196
363 1QO8 FAD 3.35196
364 5ZYN FAD 3.35196
365 3K7M FAD 3.35196
366 5FJN BE2 3.35196
367 5FJN FAD 3.35196
368 2QA1 FAD 3.35196
369 2C5A NAD 3.35196
370 2C5A GDC 3.35196
371 3EF0 ALF 3.35196
372 5KVS NAP 3.35196
373 5VN0 FAD 3.35196
374 5KVS 6XR 3.35196
375 1SOW NAD 3.35366
376 4Q9N NAI 3.3557
377 4IF4 BEF 3.36538
378 1JG3 ADN 3.40426
379 2I3G NAP 3.40909
380 5UAV NDP 3.41615
381 5UAV TFB 3.41615
382 2AOT SAH 3.42466
383 3C1O NAP 3.42679
384 2PT9 2MH 3.42679
385 2PT9 S4M 3.42679
386 5J5Z FAD 3.42742
387 1X7D ORN 3.42857
388 1X7D NAD 3.42857
389 5LOG SAH 3.43348
390 3CBG SAH 3.44828
391 1SBR VIB 3.5
392 5E9W SAH 3.52564
393 1G0N NDP 3.53357
394 1G0N PHH 3.53357
395 4FN4 NAD 3.54331
396 1FL2 FAD 3.54839
397 1RM4 NDP 3.56083
398 1ZK4 NAP 3.58566
399 3WBF NAP 3.60656
400 3WBF API 3.60656
401 3FXU TSU 3.60656
402 1BDB NAD 3.61011
403 6GAS FAD 3.62538
404 1RM0 D6P 3.63128
405 2JHF NAD 3.63128
406 1RM0 NAI 3.63128
407 1VKO NAD 3.63128
408 3T31 DCQ 3.63128
409 3T31 FAD 3.63128
410 2GZ3 NAP 3.63128
411 1E5Q NDP 3.63128
412 3AYI FAD 3.63128
413 3AYI HCI 3.63128
414 5G4L NDP 3.63128
415 2DM6 IMN 3.63128
416 2XVE FAD 3.63128
417 2XVF FAD 3.63128
418 1H6C NDP 3.63128
419 2DM6 NAP 3.63128
420 4EUE NAI 3.63128
421 1I8T FAD 3.63128
422 1H6C SIN 3.63128
423 1ELI PYC 3.63128
424 1L1E SAH 3.63128
425 3LU1 NAD 3.63128
426 1CZA G6P 3.63128
427 4O0L NDP 3.63636
428 5EES NAP 3.64372
429 2YVJ NAI 3.66972
430 2YVJ FAD 3.66972
431 1YS4 NAP 3.67232
432 3WQQ IB3 3.68852
433 3WQQ NDP 3.68852
434 5T9F NAP 3.69004
435 5T9F TYR 3.69004
436 3OFK SAH 3.7037
437 5A9A UTP 3.7037
438 3I6I NDP 3.75723
439 4JNA FAD 3.82353
440 1UDB UFG 3.84615
441 1UDB NAD 3.84615
442 6CI9 NAP 3.861
443 5AHO TLA 3.86905
444 2FKA BEF 3.87597
445 2I7C AAT 3.88693
446 1EJ0 SAM 3.88889
447 1PL6 NAD 3.91061
448 1X87 NAD 3.91061
449 1U1I NAD 3.91061
450 2JHP SAH 3.91061
451 4AP3 FAD 3.91061
452 4AP3 NAP 3.91061
453 1PL6 572 3.91061
454 4CNK FAD 3.91061
455 3LAD FAD 3.91061
456 2HMT NAI 3.91061
457 4XQC NAD 3.91061
458 2AQJ FAD 3.91061
459 2AQJ TRP 3.91061
460 4M52 FAD 3.91061
461 5J7X FAD 3.91061
462 2RGO FAD 3.91061
463 4XQC 13D 3.91061
464 4M52 M52 3.91061
465 2A8X FAD 3.91061
466 4J1Q NDP 3.91061
467 5NA1 FAD 3.91061
468 1Q1R FAD 3.91061
469 4UZI IMD 3.91061
470 4RVU NDP 3.91061
471 5BVA FAD 3.91198
472 2PZM NAD 3.93939
473 2PZM UDP 3.93939
474 1XG5 NAP 3.94265
475 5KVA SAM 3.95683
476 3WGT FAD 4.03458
477 3WGT QSC 4.03458
478 5Y8L NAD 4.0678
479 5Y8L HUI 4.0678
480 4CJX NAP 4.07523
481 1VL0 NAI 4.10959
482 1ZH8 NAP 4.11765
483 1VL8 NAP 4.11985
484 1KOL NAD 4.18994
485 1U3U BNF 4.18994
486 1U3U NAD 4.18994
487 3A06 NDP 4.18994
488 1C3V NDP 4.18994
489 4MOP 2H5 4.18994
490 6ER9 FAD 4.18994
491 6ER9 NAP 4.18994
492 3LXD FAD 4.18994
493 3A06 FOM 4.18994
494 4KOA NDP 4.2042
495 4KP7 NAP 4.21546
496 4KP7 1UQ 4.21546
497 2GLX NDP 4.21687
498 3HAD NAD 4.22078
499 1KEV NDP 4.2735
500 5L4L NAP 4.27632
501 2GN4 NDP 4.36047
502 2GN4 UD1 4.36047
503 4NBU NAI 4.4
504 3GEG NAD 4.45344
505 1CDO NAD 4.46927
506 1DJN ADP 4.46927
507 1O94 ADP 4.46927
508 2IID PHE 4.46927
509 2IID FAD 4.46927
510 1P31 EPU 4.46927
511 4J56 FAD 4.46927
512 1COY FAD 4.46927
513 3QWI CUE 4.46927
514 1COY AND 4.46927
515 1ZBQ NAD 4.46927
516 1GZ6 NAI 4.46927
517 3QWI NAP 4.46927
518 5NII FAD 4.46927
519 1P3D UMA 4.46927
520 5D4V SAH 4.47761
521 2WQ4 SFU 4.48718
522 4L8F MTX 4.48718
523 4PLT NAI 4.53172
524 4PLT OXM 4.53172
525 6AIN FAD 4.54545
526 2FZW NAD 4.55764
527 2QRK AMP 4.56853
528 1UYY BGC BGC 4.58015
529 4JBI NDP 4.59459
530 5B4T 3HR 4.61538
531 5B4T NAD 4.61538
532 1XCL SAH 4.68085
533 3Q3C NAD 4.68227
534 2F5Z FAD 4.6875
535 1GEG NAD 4.6875
536 2DT5 NAD 4.73934
537 5U5G NAP 4.74576
538 1F8F NAD 4.7486
539 1I2B USQ 4.7486
540 1I2B NAD 4.7486
541 1I2B UPG 4.7486
542 3CGD FAD 4.7486
543 3CGD COA 4.7486
544 3CGD NAD 4.7486
545 1GPE FAD 4.7486
546 3CGB FAD 4.7486
547 3X0V FAD 4.7486
548 1TB4 PEJ 4.7486
549 2RGJ FAD 4.7486
550 2HNK SAH 4.7486
551 3LN9 FLC 4.7486
552 3DUW SAH 4.7486
553 5N5D SAM 4.7486
554 5X2N ALA 4.7486
555 4GKV NAD 4.7619
556 5FI3 NAP 4.7619
557 1DSS NAD 4.8048
558 2ZB3 NDP 4.81586
559 1O5I NAD 4.81928
560 3GMB FAD 4.81928
561 1VM6 NAD 4.82456
562 5T2U NAP 4.83871
563 2JAH NDP 4.8583
564 5Y1G NAD 4.87805
565 5Y1G AKB 4.87805
566 1DIG NAP 4.90196
567 1DIG L37 4.90196
568 5VKT NAP 4.97238
569 3HVJ 705 4.97738
570 1WPQ NAD 5.02793
571 5BUK FAD 5.02793
572 4YT4 FE9 5.02793
573 2RAB NAD 5.02793
574 2VTD LKM 5.02793
575 2RAB FAD 5.02793
576 2C5S AMP 5.02793
577 3OID NDP 5.03876
578 5FFF NAP 5.05837
579 6CEP NAD 5.08982
580 6CEP OXM 5.08982
581 1LC3 NAD 5.10204
582 5O42 9JW 5.10949
583 5O42 BGC 5.10949
584 5O42 NAD 5.10949
585 1V6A TRE 5.12048
586 1DRV A3D 5.12821
587 5UR0 NAD 5.15759
588 1NYT NAP 5.16605
589 6BWL NAD 5.18293
590 1Y8Q ATP 5.20231
591 4ITU 1HS 5.20446
592 4ITU NAI 5.20446
593 3K5I AIR 5.21092
594 1NVT NAP 5.22648
595 4JJF FE9 5.23256
596 4JJF N2I 5.23256
597 2JAP NDP 5.26316
598 1NV8 MEQ 5.28169
599 1NV8 SAM 5.28169
600 6F3N NAD 5.30726
601 6F3N ADN 5.30726
602 1GR0 NAD 5.30726
603 6F3M NAD 5.30726
604 2Y6Q I7T 5.30726
605 2Z3Y F2N 5.30726
606 5EOW FAD 5.30726
607 3E1T FAD 5.30726
608 4DPL NAP 5.30726
609 3UOY NAP 5.30726
610 3UOY FAD 5.30726
611 4YKG NAD 5.30726
612 3GD4 FAD 5.30726
613 2Y6Q FAD 5.30726
614 3GD4 NAD 5.30726
615 5TUF TDC 5.30726
616 4BV6 FAD 5.30726
617 2WET FAD 5.30726
618 1X14 NAD 5.30726
619 4YKG FAD 5.30726
620 1Q9I TEO 5.30726
621 1Q9I FAD 5.30726
622 5TUF FAD 5.30726
623 1CT9 AMP 5.30726
624 1T9D P25 5.30726
625 1T9D FAD 5.30726
626 1T9D PYD 5.30726
627 1T9D 1MM 5.30726
628 2C29 NAP 5.34125
629 1I9G SAM 5.35714
630 4BVA NDP 5.37313
631 4BVA T3 5.37313
632 3SJU NDP 5.37634
633 6FDF SAH 5.38922
634 4JK3 NAD 5.40541
635 4J4H NAI 5.40541
636 4J4H 1J1 5.40541
637 3GGO ENO 5.41401
638 3GGO NAI 5.41401
639 9LDT NAD 5.42169
640 9LDB NAD 5.42169
641 1FK8 NAD 5.44747
642 2F5X ASP 5.44872
643 3O26 NDP 5.46624
644 1O8B ABF 5.47945
645 1GUZ NAD 5.48387
646 3H9E NAD 5.49133
647 4POO SAM 5.5
648 4OM8 NAD 5.50162
649 5YB7 FAD 5.51724
650 5YB7 ORN 5.51724
651 1P1C SAH 5.52764
652 3FUU ADN 5.53506
653 5EIN NAP 5.55556
654 5A1T NAI 5.57185
655 5A1T OXM 5.57185
656 4OOE FOM 5.58659
657 4OOE NDP 5.58659
658 1YKF NAP 5.58659
659 3NYC FAD 5.58659
660 3NYC IAR 5.58659
661 4TM3 FAD 5.58659
662 1GTE FAD 5.58659
663 4YNU LGC 5.58659
664 4YNU FAD 5.58659
665 4HA6 FAD 5.58659
666 1GY8 NAD 5.58659
667 5MQ6 NDP 5.58659
668 2ZB4 5OP 5.60224
669 2ZB4 NAP 5.60224
670 2A92 NAI 5.60748
671 5TUK FAD 5.63725
672 3NUG NAD 5.66802
673 4XB2 NDP 5.67164
674 4XB2 HSE 5.67164
675 4ZNO SUC 5.67164
676 5O9F 9ON 5.68182
677 5O9F NAD 5.68182
678 2G5C NAD 5.69395
679 2OWZ CIT 5.72289
680 1PR9 NAP 5.7377
681 3D3W NAP 5.7377
682 3TWO NDP 5.74713
683 6FA4 D1W 5.78035
684 6GNC FAD 5.78231
685 2HJR APR 5.86592
686 5U5N NAD 5.86592
687 4EIP FAD 5.86592
688 1YQZ FAD 5.86592
689 4U8P FDA 5.86592
690 4U8P UDP 5.86592
691 1PJS NAD 5.86592
692 4EIP K2C 5.86592
693 1P77 ATR 5.88235
694 1KJ8 GAR 5.88235
695 2WD7 NAP 5.97015
696 1Z82 NDP 5.97015
697 5WQP NAP 5.98291
698 2GDZ NAD 5.99251
699 4E13 NAD 6.00707
700 1YQD NAP 6.01093
701 1H5Q NAP 6.03774
702 2AG8 NAP 6.08365
703 5Z75 NAD 6.11621
704 4YRY NAD 6.14525
705 4YRY FAD 6.14525
706 5MBX FAD 6.14525
707 5MBX SP5 6.14525
708 4IV9 FAD 6.14525
709 1GET FAD 6.14525
710 1GET NAP 6.14525
711 1MXH DHF 6.14525
712 3FG2 FAD 6.14525
713 4C3Y FAD 6.14525
714 4C3Y ANB 6.14525
715 1MXH NAP 6.14525
716 2V6G NAP 6.14525
717 1EDO NAP 6.14754
718 5ZI9 FLC 6.15385
719 2B4Q NAP 6.15942
720 1MV8 NAD 6.19266
721 5A04 NDP 6.19469
722 5A04 BGC 6.19469
723 1G6H ADP 6.22568
724 2PK3 A2R 6.23053
725 3H5N ATP 6.23229
726 5J60 FAD 6.25
727 5OVK NDP 6.25
728 3QH2 3NM 6.33484
729 3SJ7 NDP 6.34921
730 4D42 NAP 6.38298
731 4D42 W0I 6.38298
732 1M0S CIT 6.39269
733 4ZRN UPG 6.41026
734 4ZRN NAD 6.41026
735 2VHW NAI 6.42458
736 1E3I CXF 6.42458
737 3OJO NAD 6.42458
738 1FEC FAD 6.42458
739 5JCA NDP 6.42458
740 5JCA FAD 6.42458
741 3L9W AMP 6.42458
742 2HQM FAD 6.42458
743 2B9W FAD 6.42458
744 5NMX NAP 6.42458
745 3L9W GSH 6.42458
746 2Q1W NAD 6.42458
747 5X68 FAD 6.42458
748 4TQG NDP 6.42458
749 4U7W NDP 6.42458
750 5MSO NAP 6.42458
751 5NMX FAD 6.42458
752 2CUL FAD 6.46552
753 4USI AKG 6.49351
754 2AE2 PTO 6.53846
755 2AE2 NAP 6.53846
756 4JDR FAD 6.54008
757 4B7X NAP 6.54762
758 1A5Z NAD 6.58307
759 4UP3 FAD 6.6879
760 4UP3 NDP 6.6879
761 3LZW NAP 6.70391
762 1KNR FAD 6.70391
763 1IY8 NAD 6.70391
764 3LZW FAD 6.70391
765 2X6T NAP 6.72269
766 2YY7 NAD 6.73077
767 1WOQ BGC 6.74157
768 5I7A 68Q 6.74847
769 3ORF NAD 6.77291
770 4D3F NAP 6.77419
771 2DC1 NAD 6.77966
772 1NAA 6FA 6.83919
773 1NAA ABL 6.83919
774 1ZEM NAD 6.87023
775 2QUN FUD 6.89655
776 6A3J SOE 6.98324
777 2FR1 NDP 6.98324
778 3AB1 FAD 6.98324
779 5KMS NAD 6.98324
780 4Z24 FAD 6.98324
781 5BRT CH9 6.98324
782 6A3J NAI 6.98324
783 1Z45 NAD 6.98324
784 5KMS FAD 6.98324
785 5BRT FAD 6.98324
786 3FZG SAM 7
787 1RJW ETF 7.07965
788 4MP8 MLI 7.07965
789 4MP8 NAD 7.07965
790 1GV0 NAD 7.09677
791 5ODQ FAD 7.14286
792 1H2B NAJ 7.24234
793 5LD5 NAD 7.26257
794 4OPC FDA 7.26257
795 4OPC PGT 7.26257
796 6C4T NA7 7.26257
797 2YG3 FAD 7.26257
798 5HXI FAD 7.26257
799 1YB5 NAP 7.26257
800 4TXI FAD 7.26257
801 2BRY FAD 7.26257
802 5HXI 5HN 7.26257
803 5OJI NAP 7.26257
804 5OJI ISN 7.26257
805 5TC4 NAD 7.27848
806 3MAG SAH 7.49186
807 2NPX NAD 7.5419
808 4MDH NAD 7.5419
809 3UCL NAP 7.5419
810 3UCL CYH 7.5419
811 3UCL FAD 7.5419
812 1C0I BE2 7.5419
813 1C0I FAD 7.5419
814 5MDH NAD 7.5419
815 3GRU AMP 7.5419
816 1K3T BRZ 7.5419
817 2NPX FAD 7.5419
818 3WXB NDP 7.5419
819 3A4V PYR 7.57098
820 3A4V NAD 7.57098
821 2CFC NAD 7.6
822 1LES GLC FRU 7.69231
823 2VOH CIT 7.69231
824 4L8V NAP 7.71513
825 1EQ2 NAP 7.74194
826 3MCT SAH 7.74411
827 5ZI2 ADP 7.82123
828 5ZI2 NAD 7.82123
829 1MO9 FAD 7.82123
830 1MO9 KPC 7.82123
831 2Q2V NAD 7.84314
832 5JY6 NAD 7.86517
833 2NXE SAM 7.87402
834 4D04 NAP 7.93358
835 4D04 FAD 7.93358
836 6AA8 NAD 8.10056
837 3ETG GLU 8.10056
838 3ETG GTP 8.10056
839 1REO FAD 8.10056
840 3ICS ADP 8.10056
841 3ICT ADP 8.10056
842 3ULK NDP 8.10056
843 3ICS FAD 8.10056
844 3ICR FAD 8.10056
845 3ICT FAD 8.10056
846 3ETG NDP 8.10056
847 5EPO NAP 8.10056
848 6A0S HSE 8.13253
849 6A0S NDP 8.13253
850 6BQ6 TER 8.1571
851 1B8U NAD 8.20669
852 1B8U OAA 8.20669
853 5H81 NAP 8.37989
854 2F1K NAP 8.37989
855 1PN0 FAD 8.37989
856 1PN0 IPH 8.37989
857 4XZ3 COA 8.37989
858 4DSG FAD 8.37989
859 4DSG UDP 8.37989
860 4XYM COA 8.37989
861 2JJQ SAH 8.37989
862 5THQ NDP 8.45588
863 1NFQ NAI 8.46154
864 5Z2L NDP 8.57143
865 5DF1 NAP 8.65922
866 5DF1 58X 8.65922
867 1UAY ADN 8.65922
868 1N9G NAP 8.65922
869 3TN7 NJP 8.65922
870 3VYW SAM 8.65922
871 1UJ5 5RP 8.81057
872 5W3K 9TY 8.82353
873 5W3K NDP 8.82353
874 3H8V ATP 8.90411
875 3O03 NAP 8.93471
876 3SSO SAH 8.93855
877 1HDR NAD 8.93855
878 5DNK SAH 8.93855
879 2NU8 COA 9.02778
880 1WMA NDP 9.05797
881 1WMA AB3 9.05797
882 1UXG NAD 9.06149
883 1UXG FUM 9.06149
884 5FUI APY 9.09091
885 5O4J PJL 9.12409
886 5O4J SAH 9.12409
887 5O4J 9KH 9.12409
888 4TSK NDP 9.14286
889 1AE1 NAP 9.15751
890 4EMI NAD 9.21788
891 1VJT NAD 9.21788
892 4EMI FAD 9.21788
893 3IHG FAD 9.21788
894 1R37 NAD 9.2219
895 2B5W NAP 9.2437
896 2AHR NAP 9.26641
897 5OVL NAP 9.33333
898 4J7U YTZ 9.375
899 4J7U NAP 9.375
900 1EZ4 NAD 9.43396
901 2HK9 NAP 9.45455
902 2HK9 ATR 9.45455
903 4KVL PLM 9.49721
904 5I39 FAD 9.49721
905 3A2Q ACA ACA 9.49721
906 4KWI 1TJ 9.5057
907 4KWI NAP 9.5057
908 1NVM NAD 9.56522
909 1Z6Z NAP 9.57447
910 1E3W NAD 9.57854
911 4YSX FAD 9.61539
912 1E6W NAD 9.61539
913 3G89 SAM 9.63855
914 4URF NAD 9.67742
915 4YAG NAI 9.68858
916 2PV7 NAD 9.73154
917 4XDY NAI 9.76331
918 2CDC XYP 9.77654
919 2CDC XYS 9.77654
920 1YKJ FAD 9.77654
921 1YKJ PHB 9.77654
922 2CDC NAP 9.77654
923 2E5V FAD 9.77654
924 3NGL NAP 9.78261
925 3V1Y NAD 9.79228
926 2XYQ SAH 9.83607
927 3GFB NAD 10.0559
928 1F8G NAD 10.0559
929 1NM5 NAD 10.0559
930 5KOX RFP 10.0559
931 1L7E NAI 10.0559
932 5KOX FAD 10.0559
933 2OOR NAD 10.0559
934 3HB5 NAP 10.0917
935 3VZS NAP 10.1167
936 3VZS CAA 10.1167
937 4IDC NDP 10.241
938 4IDC 1XX 10.241
939 4EMJ FAD 10.2804
940 2BOS GLA GAL GLC NBU 10.2941
941 1P0F NAP 10.3352
942 2GMH FAD 10.3352
943 5O98 NAP 10.4101
944 1FWV SGA MAG FUC 10.4478
945 3DXY SAM 10.5505
946 1WDK NAD 10.6145
947 3OA2 NAD 10.6145
948 3AD8 NAD 10.8374
949 3AD8 FAD