Receptor
PDB id Resolution Class Description Source Keywords
5z8a 1.4 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF GENB1 FROM MICROMONOSPORA ECHINOSPORA I WITH JI-20A AND PLP (EXTERNAL ALDIMINE) MICROMONOSPORA ECHINOSPORA AMINOTRANSFERASE PLP-BINDING TRANSFERASE
Ref.: COMPLETE RECONSTITUTION OF THE DIVERSE PATHWAYS OF GENTAMICIN B BIOSYNTHESIS. NAT. CHEM. BIOL. V. 15 295 2019
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PLP JIA A:501;
B:501;
 Valid;
Valid;
 none;
none;
 submit data
715.715 n/a P(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5Z8A 1.4 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF GENB1 FROM MICROMONOSPORA ECHINOSPORA I WITH JI-20A AND PLP (EXTERNAL ALDIMINE) MICROMONOSPORA ECHINOSPORA AMINOTRANSFERASE PLP-BINDING TRANSFERASE
Ref.: COMPLETE RECONSTITUTION OF THE DIVERSE PATHWAYS OF GENTAMICIN B BIOSYNTHESIS. NAT. CHEM. BIOL. V. 15 295 2019
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 313 families.
1 5Z8A - PLP JIA n/a n/a
2 6CBO - DOW C20 H36 N5 O11 P Cc1c(c(c(c....
3 5Z8K - PLP XXX n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 277 families.
1 5Z8A - PLP JIA n/a n/a
2 5Z8K - PLP XXX n/a n/a
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5Z8A - PLP JIA n/a n/a
2 6CBO - DOW C20 H36 N5 O11 P Cc1c(c(c(c....
3 5Z8K - PLP XXX n/a n/a
4 6CBN - OZY C31 H56 N7 O18 P Cc1c(c(c(c....
5 6CBK - PMP C8 H13 N2 O5 P Cc1c(c(c(c....
6 6CBL - DOW C20 H36 N5 O11 P Cc1c(c(c(c....
7 6CBM - OZY C31 H56 N7 O18 P Cc1c(c(c(c....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: PLP JIA; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 PLP JIA 1 1
2 PLP XXX 0.72807 0.942029
Similar Ligands (3D)
Ligand no: 1; Ligand: PLP JIA; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5Z8A; Ligand: PLP JIA; Similar sites found with APoc: 2
This union binding pocket(no: 1) in the query (biounit: 5z8a.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 3A8U PLP 6.40732
2 4ADC PLP 30.6636
Pocket No.: 2; Query (leader) PDB : 5Z8A; Ligand: PLP JIA; Similar sites found with APoc: 3
This union binding pocket(no: 2) in the query (biounit: 5z8a.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 3A8U PLP 6.40732
2 6S4G PMP 24.714
3 4ADC PLP 30.6636
APoc FAQ
Feedback