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Receptor
PDB id Resolution Class Description Source Keywords
6CHH 2.3 Å EC: 2.-.-.- STRUCTURE OF HUMAN NNMT IN COMPLEX WITH BISUBSTRATE INHIBITO HOMO SAPIENS PROTEIN-SMALL MOLECULE BISUBSTRATE INHIBITOR COMPLEX TRANSFTRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: DISCOVERY OF BISUBSTRATE INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE (NNMT). J. MED. CHEM. V. 61 1541 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO B:302;
B:301;
Invalid;
Invalid;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
F0P D:301;
C:301;
A:301;
B:303;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
528.561 C24 H32 N8 O6 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5YJF 2.49 Å EC: 2.-.-.- CO-CRYSTAL STRUCTURE OF HUMAN NICOTINAMIDE N-METHYLTRANSFERA WITH SMALL MOLECULE ANALOG OF NICOTINAMIDE HOMO SAPIENS NNMT NA MNA T2D TRANSFERASE
Ref.: A SMALL MOLECULE INHIBITOR OF NICOTINAMIDE N-METHYLTRANSFERASE FOR THE TREATMENT OF METABOLIC DISORDERS. SCI REP V. 8 3660 2018
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 5YJF ic50 = 1.8 uM 8WO C8 H12 N2 O2 CN1CC(=CC=....
2 5XVQ ic50 = 9 uM 8GC C7 H9 N2 O C[n+]1cccc....
3 6CHH - F0P C24 H32 N8 O6 c1cc(cc(c1....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5YJI ic50 = 5 uM 8WO C8 H12 N2 O2 CN1CC(=CC=....
2 5XVK ic50 = 9 uM 8GC C7 H9 N2 O C[n+]1cccc....
3 5YJF ic50 = 1.8 uM 8WO C8 H12 N2 O2 CN1CC(=CC=....
4 5XVQ ic50 = 9 uM 8GC C7 H9 N2 O C[n+]1cccc....
5 6CHH - F0P C24 H32 N8 O6 c1cc(cc(c1....
50% Homology Family (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3KPV Kd = 180 uM ADE C5 H5 N5 c1[nH]c2c(....
2 3KQV - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 3KR2 Kd = 7.2 uM ET2 C7 H6 F N3 c1cc2c(cc1....
4 3KQY Kd = 15 uM ES0 C7 H7 N3 O c1cc2c(c(c....
5 3KQP Kd = 380 uM ES5 C9 H8 N2 c1cc2cc(cc....
6 2G70 Ki = 17 nM HNT C10 H12 N2 O3 c1cc2c(cc1....
7 3KQS Kd = 6.3 uM AX7 C7 H7 N3 c1ccc2c(c1....
8 3KQO Kd = 140 uM ES4 C5 H3 Cl N4 c1[nH]c2c(....
9 3HCD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 2G8N Ki = 0.063 uM F83 C16 H17 Cl N2 O3 S c1cc(ccc1N....
11 3HCB - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 3HCC Ki = 13 uM LT3 C12 H12 F3 N c1cc2c(c(c....
13 3KQW Kd = 97 uM ES9 C7 H5 Cl N2 c1cc2c(cc1....
14 2G72 Ki = 315 nM F21 C14 H19 F N2 O2 S2 c1cc2c(cc1....
15 3KQQ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
16 3HCA - OTR C8 H11 N O2 c1cc(ccc1[....
17 3KPU Kd = 690 uM ES1 C9 H7 N O c1ccc2c(c1....
18 1YZ3 Ki = 1.55 nM SKA C9 H9 Cl2 N c1cc(c(c2c....
19 2AN4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
20 2G71 Ki = 35 nM FTS C13 H16 F4 N2 O2 S c1cc2c(cc1....
21 1HNN Ki = 0.58 uM SKF C9 H12 N2 O2 S c1cc2c(cc1....
22 3KPW Kd = 14 uM 1SQ C9 H8 N2 c1ccc2c(c1....
23 3KR1 Kd = 1.8 uM VGD C7 H6 Cl N3 c1cc2c(cc1....
24 2AN3 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
25 3KPJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
26 3KQT Kd = 4.6 uM ES7 C8 H9 N3 Cn1c2ccccc....
27 2OBF Ki = 1.4 nM F83 C16 H17 Cl N2 O3 S c1cc(ccc1N....
28 2AN5 Ki = 2.1 uM TTL C10 H13 N O c1ccc2c(c1....
29 3KQM Kd = 170 uM ES3 C3 H3 Br N2 c1c(nc[nH]....
30 3KPY - SAH C14 H20 N6 O5 S c1nc(c2c(n....
31 5YJI ic50 = 5 uM 8WO C8 H12 N2 O2 CN1CC(=CC=....
32 5XVK ic50 = 9 uM 8GC C7 H9 N2 O C[n+]1cccc....
33 5YJF ic50 = 1.8 uM 8WO C8 H12 N2 O2 CN1CC(=CC=....
34 5XVQ ic50 = 9 uM 8GC C7 H9 N2 O C[n+]1cccc....
35 6CHH - F0P C24 H32 N8 O6 c1cc(cc(c1....
36 2A14 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: F0P; Similar ligands found: 67
No: Ligand ECFP6 Tc MDL keys Tc
1 F0P 1 1
2 62X 0.6 0.883117
3 K15 0.594595 0.906667
4 KB1 0.551724 0.905405
5 SA8 0.551402 0.891892
6 KH3 0.545455 0.894737
7 SAH 0.504505 0.915493
8 SFG 0.490909 0.9
9 SAI 0.477876 0.902778
10 5X8 0.477477 0.887324
11 S7M 0.474138 0.844156
12 EEM 0.469565 0.844156
13 EP4 0.460784 0.8
14 DZD 0.452555 0.814815
15 DQV 0.449612 0.7625
16 LAD 0.447154 0.8375
17 0UM 0.446281 0.905405
18 5CD 0.445545 0.805556
19 SMM 0.436975 0.8125
20 SAM 0.435897 0.844156
21 SXZ 0.432 0.893333
22 A5D 0.431034 0.810811
23 RAB 0.43 0.794521
24 XYA 0.43 0.794521
25 ADN 0.43 0.794521
26 CA0 0.429825 0.753086
27 MHZ 0.429825 0.825
28 MAO 0.428571 0.780488
29 DTA 0.428571 0.810811
30 A6D 0.427419 0.722892
31 KAA 0.424 0.733333
32 A 0.422018 0.725
33 AMP 0.422018 0.725
34 5N5 0.421569 0.819444
35 GJV 0.419643 0.818182
36 XAH 0.418605 0.795181
37 6RE 0.418182 0.805195
38 A4D 0.417476 0.794521
39 F2R 0.417266 0.776471
40 A3P 0.415929 0.725
41 OOB 0.414634 0.78481
42 DSH 0.414414 0.916667
43 SRP 0.413223 0.7875
44 YLB 0.411765 0.819277
45 YLC 0.411765 0.817073
46 AMO 0.41129 0.7875
47 MTA 0.411215 0.797297
48 FA5 0.410853 0.810127
49 ABM 0.410714 0.707317
50 YLP 0.410448 0.819277
51 ME8 0.409449 0.77381
52 A7D 0.408696 0.849315
53 SON 0.408696 0.7875
54 5AL 0.408333 0.7625
55 SRA 0.405405 0.690476
56 3UK 0.404762 0.775
57 3DH 0.40367 0.797297
58 M2T 0.401869 0.75641
59 AOC 0.401786 0.797297
60 SSA 0.401639 0.681319
61 GSU 0.401575 0.719101
62 B5V 0.401575 0.765432
63 WAQ 0.401575 0.835443
64 YAP 0.4 0.8
65 DSZ 0.4 0.7
66 LSS 0.4 0.666667
67 8PZ 0.4 0.7
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5YJF; Ligand: 8WO; Similar sites found with APoc: 363
This union binding pocket(no: 1) in the query (biounit: 5yjf.bio3) has 31 residues
No: Leader PDB Ligand Sequence Similarity
1 3R51 MMA None
2 5TVI O8N None
3 3OFK SAH None
4 2GN4 NDP 1.05634
5 2BD0 NAP 1.63934
6 3TLJ SAH 1.76056
7 3MA0 XYP 1.76056
8 1W6U NAP 1.76056
9 1W8D NAP 1.76056
10 1W73 NAP 1.76056
11 4Q9N NAI 1.76056
12 6FDF SAH 2.11268
13 5KOK S9T 2.11268
14 3HQ9 OXL 2.11268
15 3FSY SCA 2.11268
16 6GKV SAH 2.11268
17 5KOK R9T 2.11268
18 5OCM NAP 2.11268
19 5KOK SAH 2.11268
20 3HB5 NAP 2.11268
21 4O0L NDP 2.18182
22 4FN4 NAD 2.3622
23 3TVQ DQH 2.36686
24 5T2U NAP 2.41935
25 4LHD GLY 2.46479
26 3VSE SAH 2.46479
27 1L1E SAH 2.46479
28 2DPM SAM 2.46479
29 3FPF TNA 2.46479
30 3FPF MTA 2.46479
31 1TPY SAH 2.46479
32 1KPG SAH 2.46479
33 1KPH SAH 2.46479
34 2YY7 NAD 2.46479
35 1XG5 NAP 2.50896
36 6CI9 NAP 2.7027
37 3FRH SAH 2.7668
38 4NBU NAI 2.8
39 2IZ1 ATR 2.8169
40 4ONQ SFG 2.8169
41 3L9W AMP 2.8169
42 5K4W THR 2.8169
43 5U5G NAP 2.8169
44 1LSS NAD 2.85714
45 3A27 SAM 2.94118
46 1BC5 SAH 2.97398
47 2BZG SAH 3.01724
48 2DTX BMA 3.0303
49 5GT9 NAP 3.04183
50 4H69 10Y 3.09278
51 5OVK NDP 3.125
52 2ZWA SAH 3.16901
53 5E9W SAH 3.16901
54 1KGZ PRP 3.16901
55 1V35 NAI 3.16901
56 5FUB SAH 3.16901
57 3FPZ AHZ 3.16901
58 2Q46 NAP 3.16901
59 4RYV ZEA 3.22581
60 3NUG NAD 3.23887
61 3W6G FLC 3.24074
62 5U83 ZN8 3.30189
63 1P77 ATR 3.30882
64 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 3.34728
65 5DM1 SAH 3.37079
66 5DM1 5D7 3.37079
67 1G60 SAM 3.46154
68 2HMT NAI 3.47222
69 3A06 NDP 3.52113
70 4D42 W0I 3.52113
71 4D42 NAP 3.52113
72 5AZC PGT 3.52113
73 2PK3 A2R 3.52113
74 1MV8 NAD 3.52113
75 4N49 SAM 3.52113
76 1MUU NAD 3.52113
77 1T3D CYS 3.52113
78 1WG8 SAM 3.52113
79 1VE3 SAM 3.52423
80 4FC7 COA 3.61011
81 4FC7 NAP 3.61011
82 1BDB NAD 3.61011
83 1UAY ADN 3.71901
84 6BR7 BEF 3.7594
85 5MGZ SAH 3.81356
86 4Y9D NAI 3.87324
87 3ABI NAD 3.87324
88 3A4V PYR 3.87324
89 3A4V NAD 3.87324
90 4XUC SAM 3.87324
91 4XUC 43G 3.87324
92 6C4T NA7 3.87324
93 2IF8 ADP 3.87324
94 5LX9 OLB 3.87324
95 4IBF 1D5 3.87597
96 5M58 SAH 3.91304
97 5WHU SIA GAL GLC 4.02685
98 3HVJ 705 4.0724
99 5THZ SAH 4.22535
100 5THY SAH 4.22535
101 6D6Y SAH 4.22535
102 3PT9 SAH 4.22535
103 2ZIF SAM 4.22535
104 4D3F NAP 4.22535
105 6C4N NAP 4.22535
106 4C4A SAH 4.22535
107 2Q0L NAP 4.22535
108 5HYR EST 4.26357
109 5L95 AMP 4.30108
110 2RH4 EMO 4.33213
111 2WA2 SAM 4.34783
112 3EGI ADP 4.36893
113 1O5I NAD 4.41767
114 3FUU ADN 4.42804
115 1WUW TSU 4.44444
116 3DUW SAH 4.4843
117 3D3W NAP 4.5082
118 1Q7B NAP 4.5082
119 1PR9 NAP 4.5082
120 3I53 SAH 4.51807
121 5E8J SAH 4.54545
122 4YAC NAI 4.57746
123 3X0D SAH 4.57746
124 5YIF 8VR 4.57746
125 3NDJ JHZ 4.57746
126 3NDJ SAH 4.57746
127 5HJM MTA 4.57746
128 4UCI SAM 4.57746
129 3CH6 NAP 4.57746
130 3CH6 311 4.57746
131 5FWA J7C 4.57746
132 5VN0 NAI 4.57746
133 4G5H NAP 4.57746
134 4G5H UD7 4.57746
135 1G0N PHH 4.59364
136 1G0N NDP 4.59364
137 2NUO BGC 4.91803
138 2NU5 NAG 4.91803
139 2HYQ MAN MAN 4.91803
140 2GUD BMA 4.91803
141 2GUD MAN 4.91803
142 5BJX NAD 4.92958
143 5BJX UDP 4.92958
144 5CIC 51R 4.92958
145 1E5Q NDP 4.92958
146 6EL3 NAP 4.92958
147 5V6F MAN BMA MAN 4.92958
148 1ZEM NAD 4.96183
149 5XLX SAH 4.96454
150 3A25 SAM 4.98339
151 1NNU TCT 5
152 1NNU NAD 5
153 2PWY SAH 5.03876
154 1QXA GLY GLY GLY 5.10638
155 1UZN NAP 5.26316
156 2UYQ SAM 5.28169
157 4DCM SAM 5.28169
158 1RJD SAM 5.28169
159 1ZGS XMM 5.28169
160 1NV8 SAM 5.28169
161 1NV8 MEQ 5.28169
162 5W7B MYR 5.28169
163 5W7R 9Z7 5.28169
164 3MCT SAH 5.28169
165 3M6W SAM 5.28169
166 5W7R SAH 5.28169
167 3Q87 SAM 5.29412
168 5MPT SAH 5.31401
169 1IM8 SAI 5.32787
170 5X20 NAD 5.44872
171 3DXY SAM 5.50459
172 3QWI CUE 5.55556
173 3QWI NAP 5.55556
174 5FA5 MTA 5.6338
175 6ARJ BW4 5.6338
176 6ARJ SAH 5.6338
177 5X62 SAH 5.6338
178 4X60 3XV 5.6338
179 4X60 SFG 5.6338
180 5ICE 2H4 5.6338
181 5DX0 SFG 5.6338
182 5DWQ SFG 5.6338
183 5ICE SAH 5.6338
184 4GQB 0XU 5.6338
185 5IL1 SAM 5.6338
186 5K7U SAM 5.6338
187 4IWN GEK 5.67686
188 2AG5 NAD 5.69106
189 3RKR NAP 5.72519
190 4OBW SAM 5.83658
191 1GEG NAD 5.85938
192 1AE1 NAP 5.86081
193 3MB5 SAM 5.88235
194 4Y30 SAH 5.98592
195 4Y30 49L 5.98592
196 3O7W SAM 5.98592
197 5L1O 7PF 5.98592
198 3A4T SFG 5.98592
199 2JK0 ASP 5.98592
200 6B92 SAH 5.98592
201 5OKL PAM 6.33803
202 3VYW SAM 6.33803
203 5MLR GRQ 6.33803
204 5MLR NAP 6.33803
205 1V59 NAD 6.33803
206 4ITU NAI 6.33803
207 4ITU 1HS 6.33803
208 4URF NAD 6.45161
209 2HK9 ATR 6.54545
210 2XYQ SAH 6.55738
211 5O42 BGC 6.56934
212 5O42 9JW 6.56934
213 5O42 NAD 6.56934
214 4TUZ 36J 6.66667
215 4A6D SAM 6.69014
216 3H8V ATP 6.69014
217 4AZW SAM 6.69014
218 2E7Z MGD 6.69014
219 3C6K MTA 6.69014
220 3C6K SPD 6.69014
221 3GU3 SAH 6.69014
222 6GFK SAH 6.77291
223 3FZG SAM 7
224 5WP5 SAH 7.04225
225 1EJ0 SAM 7.22222
226 5FFF NAP 7.393
227 5FFF 5XC 7.393
228 1YXM ADE 7.39437
229 2JJQ SAH 7.39437
230 5XNC MTA 7.39437
231 5ERG SAM 7.39437
232 3GRU AMP 7.39437
233 2FK8 SAM 7.39437
234 5W3Y ACO 7.39437
235 3SJU NDP 7.52688
236 3VC1 SAH 7.69231
237 3VC1 GST 7.69231
238 5FEU NAP 7.74648
239 2HIM ASN 7.74648
240 4J1Q NDP 7.74648
241 5T9E NAP 7.74908
242 1QAN SAH 7.78689
243 3GCZ SAM 7.80142
244 3KO0 TFP 7.92079
245 1TL2 NDG 8.05085
246 3BGD SAH 8.07692
247 3BGD PM6 8.07692
248 2AE2 PTO 8.07692
249 2AE2 NAP 8.07692
250 5THQ NDP 8.08823
251 4PIO SAH 8.09859
252 4PIO AVI 8.09859
253 3O03 NAP 8.09859
254 3ITJ CIT 8.09859
255 5T9F TYR 8.11808
256 4QTU SAM 8.14815
257 3TN7 NJP 8.17121
258 3GDH SAH 8.29876
259 1R18 SAH 8.37004
260 2PXX SAH 8.37209
261 5JJR SAH 8.4507
262 2EFJ SAH 8.4507
263 2EG5 SAH 8.4507
264 1XCL SAH 8.51064
265 4R6W PC 8.52713
266 4R6W SAH 8.52713
267 2AG8 NAP 8.74525
268 3JWH SAH 8.75576
269 5WP4 SAH 8.80282
270 3ELW GP3 8.80282
271 3ELW SAM 8.80282
272 2V6G NAP 8.80282
273 4CQM NAP 8.81226
274 5FTW SAH 8.98438
275 5CUQ NSC 8.98876
276 1JOT GAL A2G 9.02256
277 1UGY GLA GLC 9.02256
278 1JAC AMG 9.02256
279 1UGY GLA BGC 9.02256
280 1WS4 AMG 9.02256
281 1UGW GAL 9.02256
282 1WS4 GYP 9.02256
283 4AKB GAL 9.02256
284 1M26 GAL A2G 9.02256
285 1WS5 MMA 9.02256
286 1TOQ AMG 9.02256
287 1KUJ MMA 9.02256
288 3QOX SAH 9.15493
289 5MW4 5JU 9.15493
290 1XHL NDP 9.15493
291 4POO SAM 9.5
292 5DLY 5D7 9.50704
293 5DLY SAH 9.50704
294 2EJU SAH 9.50704
295 2P41 SAH 9.50704
296 3RJ5 NAD 9.50704
297 3B1F NAD 9.50704
298 3P9C SAH 9.50704
299 5W7M SAH 9.85915
300 2JHP SAH 9.85915
301 4DMG SAM 9.85915
302 1X87 NAD 9.85915
303 5L53 NAP 9.85915
304 3G2O SAM 10.0334
305 1P1C SAH 10.0503
306 3GWZ SAH 10.2113
307 3GXO SAH 10.2113
308 3TKY SAH 10.2113
309 2NXE SAM 10.2362
310 6DUB SAH 10.3604
311 1VL8 NAP 10.4869
312 1JQD SAH 10.5634
313 1JQD HSM 10.5634
314 2AOT SAH 10.5634
315 5CGE 51F 10.8303
316 4NBW NAD 10.8949
317 1JG3 ADN 11.0638
318 2PX8 SAH 11.1524
319 1NW5 SAM 11.6197
320 1DL5 SAH 11.6197
321 1XKQ NDP 11.7857
322 1Z3C SA8 12.0805
323 1G55 SAH 12.3239
324 2XVM SAH 12.5628
325 2BGM NAJ 12.5899
326 2VDV SAM 12.6016
327 4M38 SAH 12.6761
328 1ZQ9 SAM 12.6761
329 1KYZ SAH 12.6761
330 4M37 SAH 12.6761
331 2YX1 SFG 13.0282
332 4FZV SAM 13.0282
333 1N2X SAM 13.3803
334 5YF1 SFG 14.0845
335 5YF1 8V0 14.0845
336 5ZW3 SAH 14.2222
337 5EEH P9P 14.7887
338 5EEH SAH 14.7887
339 1I1N SAH 15.1408
340 3G89 SAM 16.0643
341 3LCC SAH 16.1702
342 3EVG SAH 17.0909
343 5E1M SAH 17.2535
344 5E1M PRO PRO LYS ARG ILE ALA 17.2535
345 3KIF GDL 17.9245
346 3WUR O4B 18.1287
347 1WY7 SAH 18.3575
348 5YEC ATP 18.4874
349 5GWX SAM 19.0141
350 5GWX SAR 19.0141
351 6GMN F4E 19.2308
352 2Y69 CHD 20.2703
353 1XDS SAM 20.7746
354 5DXA SFG 21.0526
355 5DX1 SFG 21.0526
356 5DX8 SFG 21.0526
357 4M73 SAH 21.4789
358 4M73 M72 21.4789
359 1QZZ SAM 22.8873
360 3DMH SAM 23.9437
361 3DMH GMP 23.9437
362 5W7K SAH 30.6338
363 1U2Z SAH 36.2676
Pocket No.: 2; Query (leader) PDB : 5YJF; Ligand: SAH; Similar sites found with APoc: 361
This union binding pocket(no: 2) in the query (biounit: 5yjf.bio3) has 34 residues
No: Leader PDB Ligand Sequence Similarity
1 3OFK SAH None
2 3R51 MMA None
3 3TL1 JRO None
4 1O68 KIV 1.09091
5 2BD0 NAP 1.63934
6 3TLJ SAH 1.76056
7 1W6U NAP 1.76056
8 4Q9N NAI 1.76056
9 1W8D NAP 1.76056
10 1W73 NAP 1.76056
11 5KOK SAH 2.11268
12 6FDF SAH 2.11268
13 3HQ9 OXL 2.11268
14 3FSY SCA 2.11268
15 5KOK S9T 2.11268
16 6GKV SAH 2.11268
17 1KYA XYD 2.11268
18 5OCM NAP 2.11268
19 5KOK R9T 2.11268
20 1DE6 RNS 2.11268
21 4O0L NDP 2.18182
22 4FN4 NAD 2.3622
23 5T2U NAP 2.41935
24 4LHD GLY 2.46479
25 1TPY SAH 2.46479
26 1KPG SAH 2.46479
27 1KPH SAH 2.46479
28 3VSE SAH 2.46479
29 1L1E SAH 2.46479
30 2DPM SAM 2.46479
31 3H5N ATP 2.46479
32 1XG5 NAP 2.50896
33 6CI9 NAP 2.7027
34 3FRH SAH 2.7668
35 1Q8Q MAN MMA 2.77778
36 1Q8S MAN MMA 2.77778
37 1UKG MMA 2.77778
38 2PHX MAN MAN 2.77778
39 2IZ1 ATR 2.8169
40 4ONQ SFG 2.8169
41 3AI0 PNW 2.8169
42 3L9W AMP 2.8169
43 4RQL SNE 2.8169
44 5U5G NAP 2.8169
45 1LSS NAD 2.85714
46 3A27 SAM 2.94118
47 1BC5 SAH 2.97398
48 2BZG SAH 3.01724
49 5GT9 NAP 3.04183
50 1Q0S SAH 3.0888
51 5OVK NDP 3.125
52 5E9W SAH 3.16901
53 4K90 MLA 3.16901
54 2ZWA SAH 3.16901
55 1V08 NTZ 3.16901
56 5FUB SAH 3.16901
57 2Q46 NAP 3.16901
58 4RYV ZEA 3.22581
59 3NUG NAD 3.23887
60 3W6G FLC 3.24074
61 5U83 ZN8 3.30189
62 1P77 ATR 3.30882
63 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 3.34728
64 5DM1 5D7 3.37079
65 5DM1 SAH 3.37079
66 5URY PAM 3.42466
67 1G60 SAM 3.46154
68 2HMT NAI 3.47222
69 2BMB PMM 3.48624
70 3A06 NDP 3.52113
71 3X01 AMP 3.52113
72 1WG8 SAM 3.52113
73 4D42 NAP 3.52113
74 4D42 W0I 3.52113
75 2PK3 A2R 3.52113
76 1MV8 NAD 3.52113
77 4N49 SAM 3.52113
78 1MUU NAD 3.52113
79 1T3D CYS 3.52113
80 1VE3 SAM 3.52423
81 4FC7 COA 3.61011
82 4FC7 NAP 3.61011
83 1UAY ADN 3.71901
84 6BR7 BEF 3.7594
85 5MGZ SAH 3.81356
86 4Y9D NAI 3.87324
87 4XDA RIB 3.87324
88 6C4T NA7 3.87324
89 2IF8 ADP 3.87324
90 3ABI NAD 3.87324
91 1FUT 2GP 3.87324
92 4XUC 43G 3.87324
93 4XUC SAM 3.87324
94 3A4V NAD 3.87324
95 3A4V PYR 3.87324
96 4IBF 1D5 3.87597
97 5M58 SAH 3.91304
98 5TQZ GLC 4
99 5WHU SIA GAL GLC 4.02685
100 5THZ SAH 4.22535
101 5THY SAH 4.22535
102 4C4A SAH 4.22535
103 6D6Y SAH 4.22535
104 3PT9 SAH 4.22535
105 2ZIF SAM 4.22535
106 4D3F NAP 4.22535
107 6C4N NAP 4.22535
108 2Q0L NAP 4.22535
109 1V7Z CRN 4.23077
110 5HYR EST 4.26357
111 5L95 AMP 4.30108
112 2RH4 EMO 4.33213
113 2WA2 SAM 4.34783
114 3EGI ADP 4.36893
115 1O5I NAD 4.41767
116 3FUU ADN 4.42804
117 3DUW SAH 4.4843
118 1Q7B NAP 4.5082
119 3I53 SAH 4.51807
120 5E8J SAH 4.54545
121 4YAC NAI 4.57746
122 3X0D SAH 4.57746
123 5YIF 8VR 4.57746
124 5HJM MTA 4.57746
125 4UCI SAM 4.57746
126 3NDJ SAH 4.57746
127 3NDJ JHZ 4.57746
128 5FWA J7C 4.57746
129 3DXW ICC 4.57746
130 5OUH L0B 4.87805
131 2NUO BGC 4.91803
132 2NU5 NAG 4.91803
133 2HYQ MAN MAN 4.91803
134 2GUD BMA 4.91803
135 2GUD MAN 4.91803
136 5CIC 51R 4.92958
137 1E5Q NDP 4.92958
138 5BJX NAD 4.92958
139 5BJX UDP 4.92958
140 5FXD H7Y 4.92958
141 6EL3 NAP 4.92958
142 2PT9 S4M 4.92958
143 1ZEM NAD 4.96183
144 5XLX SAH 4.96454
145 3A25 SAM 4.98339
146 2PWY SAH 5.03876
147 1QXA GLY GLY GLY 5.10638
148 1UZN NAP 5.26316
149 5W7R SAH 5.28169
150 4DCM SAM 5.28169
151 2UYQ SAM 5.28169
152 1RJD SAM 5.28169
153 5W7B MYR 5.28169
154 1ZGS XMM 5.28169
155 3MCT SAH 5.28169
156 1NV8 SAM 5.28169
157 1NV8 MEQ 5.28169
158 3M6W SAM 5.28169
159 5W7R 9Z7 5.28169
160 2PFZ PCA 5.28169
161 4CS9 AMP 5.29101
162 3Q87 SAM 5.29412
163 5MPT SAH 5.31401
164 1IM8 SAI 5.32787
165 5X20 NAD 5.44872
166 3DXY SAM 5.50459
167 2WT9 NIO 5.53191
168 5FA5 MTA 5.6338
169 5DX0 SFG 5.6338
170 6ARJ BW4 5.6338
171 6ARJ SAH 5.6338
172 5DWQ SFG 5.6338
173 5IL1 SAM 5.6338
174 5ICE 2H4 5.6338
175 4X60 SFG 5.6338
176 4X60 3XV 5.6338
177 5ICE SAH 5.6338
178 4GQB 0XU 5.6338
179 5X62 SAH 5.6338
180 5K7U SAM 5.6338
181 4IWN GEK 5.67686
182 2AG5 NAD 5.69106
183 3RKR NAP 5.72519
184 4OBW SAM 5.83658
185 1GEG NAD 5.85938
186 3MB5 SAM 5.88235
187 6B92 SAH 5.98592
188 4Y30 49L 5.98592
189 4Y30 SAH 5.98592
190 5L1O 7PF 5.98592
191 2JK0 ASP 5.98592
192 3A4T SFG 5.98592
193 3O7W SAM 5.98592
194 2WVZ KIF 5.98592
195 3TKA SAM 6.33803
196 1SQI 869 6.33803
197 1V59 NAD 6.33803
198 3VYW SAM 6.33803
199 4URF NAD 6.45161
200 2HK9 ATR 6.54545
201 2XYQ SAH 6.55738
202 5O42 BGC 6.56934
203 5O42 9JW 6.56934
204 5O42 NAD 6.56934
205 4TUZ 36J 6.66667
206 3GU3 SAH 6.69014
207 4A6D SAM 6.69014
208 3H8V ATP 6.69014
209 4AZW SAM 6.69014
210 3C6K MTA 6.69014
211 3C6K SPD 6.69014
212 6GFK SAH 6.77291
213 1SQL GUN 6.84932
214 3FZG SAM 7
215 5WP5 SAH 7.04225
216 1EJ0 SAM 7.22222
217 5FFF NAP 7.393
218 1YXM ADE 7.39437
219 2JJQ SAH 7.39437
220 2FK8 SAM 7.39437
221 5XNC MTA 7.39437
222 2Q1A 2KT 7.39437
223 3GRU AMP 7.39437
224 5ERG SAM 7.39437
225 5W3Y ACO 7.39437
226 3SJU NDP 7.52688
227 3VC1 GST 7.69231
228 3VC1 SAH 7.69231
229 2HIM ASN 7.74648
230 4PVR ASP 7.74648
231 2HIM ASP 7.74648
232 4BLW SAH 7.74648
233 4J1Q NDP 7.74648
234 5T9E NAP 7.74908
235 1QAN SAH 7.78689
236 3GCZ SAM 7.80142
237 3KO0 TFP 7.92079
238 1TL2 NDG 8.05085
239 3BGD PM6 8.07692
240 3BGD SAH 8.07692
241 5THQ NDP 8.08823
242 4PIO SAH 8.09859
243 4PIO AVI 8.09859
244 3O03 NAP 8.09859
245 3ITJ CIT 8.09859
246 4QTU SAM 8.14815
247 3TN7 NJP 8.17121
248 3GDH SAH 8.29876
249 1R18 SAH 8.37004
250 2PXX SAH 8.37209
251 2EG5 SAH 8.4507
252 5JJR SAH 8.4507
253 2EFJ SAH 8.4507
254 1XCL SAH 8.51064
255 4R6W PC 8.52713
256 4R6W SAH 8.52713
257 1K9J NAG MAN MAN MAN NAG 8.63309
258 2AG8 NAP 8.74525
259 3JWH SAH 8.75576
260 5WP4 SAH 8.80282
261 5A7V MAN 8.80282
262 3ELW SAM 8.80282
263 2V6G NAP 8.80282
264 4CQM NAP 8.81226
265 5FTW SAH 8.98438
266 5CUQ NSC 8.98876
267 4AKB GAL 9.02256
268 1UGW GAL 9.02256
269 1WS4 AMG 9.02256
270 1UGY GLA BGC 9.02256
271 1WS4 GYP 9.02256
272 1UGY GLA GLC 9.02256
273 1TOQ AMG 9.02256
274 1JOT GAL A2G 9.02256
275 1JAC AMG 9.02256
276 1WS5 MMA 9.02256
277 1KUJ MMA 9.02256
278 3LLZ GAL NGA 9.02256
279 2BJ4 OHT 9.12698
280 3QOX SAH 9.15493
281 5MW4 5JU 9.15493
282 1XHL NDP 9.15493
283 4POO SAM 9.5
284 5DLY 5D7 9.50704
285 5DLY SAH 9.50704
286 2EJU SAH 9.50704
287 2P41 SAH 9.50704
288 3B1F NAD 9.50704
289 5W7M SAH 9.85915
290 2JHP SAH 9.85915
291 4DMG SAM 9.85915
292 1X87 NAD 9.85915
293 5L53 NAP 9.85915
294 3G2O SAM 10.0334
295 5ICK FEZ 10.0437
296 1P1C SAH 10.0503
297 3GWZ SAH 10.2113
298 3GXO SAH 10.2113
299 3TKY SAH 10.2113
300 5Z20 OXM 10.2113
301 2QRD ADP 10.219
302 2NXE SAM 10.2362
303 6DUB SAH 10.3604
304 1FWV SGA MAG FUC 10.4478
305 1JQD SAH 10.5634
306 1JQD HSM 10.5634
307 2AOT SAH 10.5634
308 5CGE 51F 10.8303
309 4NBW NAD 10.8949
310 1JG3 ADN 11.0638
311 2PX8 SAH 11.1524
312 1NW5 SAM 11.6197
313 1DL5 SAH 11.6197
314 1XKQ NDP 11.7857
315 1Z3C SA8 12.0805
316 2WG9 OCA 12.3077
317 1G55 SAH 12.3239
318 1H5R G1P 12.3239
319 2XVM SAH 12.5628
320 2BGM NAJ 12.5899
321 2VDV SAM 12.6016
322 4M37 SAH 12.6761
323 4M38 SAH 12.6761
324 1ZQ9 SAM 12.6761
325 1KYZ SAH 12.6761
326 2YX1 SFG 13.0282
327 4FZV SAM 13.0282
328 1N2X SAM 13.3803
329 5AYI BGC 13.7324
330 5YF1 SFG 14.0845
331 5YF1 8V0 14.0845
332 5ZW3 SAH 14.2222
333 5EEH P9P 14.7887
334 5EEH SAH 14.7887
335 1I1N SAH 15.1408
336 6FHQ DE5 15.5172
337 3G89 SAM 16.0643
338 3RLB VIB 16.1458
339 3LCC SAH 16.1702
340 3EVG SAH 17.0909
341 5E1M PRO PRO LYS ARG ILE ALA 17.2535
342 5E1M SAH 17.2535
343 5JNW 6LJ 17.6101
344 3KIF GDL 17.9245
345 3WUR O4B 18.1287
346 1WY7 SAH 18.3575
347 5YEC ATP 18.4874
348 5GWX SAM 19.0141
349 5GWX SAR 19.0141
350 1XDS SAM 20.7746
351 3TTM PUT 20.7746
352 5DXA SFG 21.0526
353 5DX1 SFG 21.0526
354 5DX8 SFG 21.0526
355 4M73 SAH 21.4789
356 4M73 M72 21.4789
357 1QZZ SAM 22.8873
358 3DMH SAM 23.9437
359 3DMH GMP 23.9437
360 5W7K SAH 30.6338
361 1U2Z SAH 36.2676
Pocket No.: 3; Query (leader) PDB : 5YJF; Ligand: 8WO; Similar sites found with APoc: 88
This union binding pocket(no: 3) in the query (biounit: 5yjf.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 3KPE TM3 None
2 2DT9 THR None
3 4O1M NAD 1.76056
4 1NZY BCA 1.85874
5 1YYE 196 1.86567
6 1PZM 5GP 1.89573
7 5T96 79J 2.11268
8 2O07 MTA 2.11268
9 5TED SKM 2.21239
10 3S1S SAH 2.46479
11 3H5N ATP 2.46479
12 6HKE LMR 2.46479
13 1Q8S MAN MMA 2.77778
14 1Q8Q MAN MMA 2.77778
15 1UKG MMA 2.77778
16 2PHX MAN MAN 2.77778
17 4PZ6 GMP 2.8169
18 4NBT NAD 2.91667
19 5WBF LAC 2.96296
20 2VWA PTY 2.9703
21 1Q0S SAH 3.0888
22 1XXR MAN 3.10559
23 4K90 MLA 3.16901
24 1DMH MCT 3.16901
25 5WXU FLC 3.16901
26 1V08 NTZ 3.16901
27 3NVD OAN 3.16901
28 1OBB NAD 3.16901
29 2CFC KPC 3.2
30 1KZL CRM 3.36538
31 1MZV AMP 3.40426
32 4PBG BGP 3.52113
33 3X01 AMP 3.52113
34 5HSS 64Z 3.52113
35 1Y8Q ATP 3.52113
36 1FLJ GSH 3.84615
37 1B09 PC 3.8835
38 2VT3 ATP 4.18605
39 4IF4 BEF 4.32692
40 3PCJ INO 4.5
41 3DXW ICC 4.57746
42 4D1J DGJ 4.57746
43 2PT9 S4M 4.92958
44 3NMV PYV 5.05618
45 3LEK BCW 5.22876
46 3MAG SAH 5.28169
47 4CS9 AMP 5.29101
48 4DOO DAO 5.36585
49 3C3Y SAH 5.48523
50 2OEM 1AE 5.98592
51 3TDC 0EU 5.98592
52 5CKS GAL 5.98592
53 3TKA SAM 6.33803
54 2JC9 ADN 6.69014
55 3GCM 5GP 7.31707
56 5OFW 9TW 7.62332
57 4C2W ANP 7.69231
58 5JDC 6JP 8.09859
59 1ZX5 LFR 8.09859
60 1NXJ TLA 8.19672
61 2B4Q NAP 8.33333
62 5C2N NAG 8.33333
63 5TH5 MET 8.36502
64 3WMX NAD 8.4507
65 5N53 8NB 8.71795
66 5A7V MAN 8.80282
67 3LLZ GAL NGA 9.02256
68 1VJT NAD 9.15493
69 3N8K D1X 9.30233
70 3EVF GTA 9.38628
71 2IDV M7G 9.60452
72 3BY9 SIN 10
73 5ICK FEZ 10.0437
74 5ZZ6 ADP 10.0962
75 3TKY N7I 10.2113
76 2QRD ADP 10.219
77 1FWV SGA MAG FUC 10.4478
78 3HPY MCT 10.5634
79 3O94 NCA 10.9005
80 2Q28 ADP 11.2676
81 1IY8 NAD 11.6105
82 1J0I GLC GLC GLC 11.9718
83 2WG9 OCA 12.3077
84 5H9Q TD2 13.5484
85 3I7S PYR 13.7324
86 3KIH GDL 14.433
87 4WGF HX2 15.122
88 5X3R 7Y3 28.7805
Pocket No.: 4; Query (leader) PDB : 5YJF; Ligand: SAH; Similar sites found with APoc: 89
This union binding pocket(no: 4) in the query (biounit: 5yjf.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 5TVI O8N None
2 3KPE TM3 None
3 2DT9 THR None
4 4O1M NAD 1.76056
5 1NZY BCA 1.85874
6 1YYE 196 1.86567
7 1PZM 5GP 1.89573
8 5T96 79J 2.11268
9 2O07 MTA 2.11268
10 5TED SKM 2.21239
11 3S1S SAH 2.46479
12 3FPF TNA 2.46479
13 3FPF MTA 2.46479
14 6HKE LMR 2.46479
15 2YY7 NAD 2.46479
16 4NBU NAI 2.8
17 4PZ6 GMP 2.8169
18 4NBT NAD 2.91667
19 5WBF LAC 2.96296
20 2VWA PTY 2.9703
21 1XXR MAN 3.10559
22 1KGZ PRP 3.16901
23 1DMH MCT 3.16901
24 5WXU FLC 3.16901
25 3FPZ AHZ 3.16901
26 1V35 NAI 3.16901
27 3NVD OAN 3.16901
28 1OBB NAD 3.16901
29 2CFC KPC 3.2
30 1KZL CRM 3.36538
31 1MZV AMP 3.40426
32 4PBG BGP 3.52113
33 5AZC PGT 3.52113
34 5HSS 64Z 3.52113
35 1Y8Q ATP 3.52113
36 1FLJ GSH 3.84615
37 5LX9 OLB 3.87324
38 1B09 PC 3.8835
39 3HVJ 705 4.0724
40 2VT3 ATP 4.18605
41 4IF4 BEF 4.32692
42 3PCJ INO 4.5
43 3D3W NAP 4.5082
44 1PR9 NAP 4.5082
45 4D1J DGJ 4.57746
46 1NNU NAD 5
47 1NNU TCT 5
48 3NMV PYV 5.05618
49 3LEK BCW 5.22876
50 3MAG SAH 5.28169
51 4DOO DAO 5.36585
52 3C3Y SAH 5.48523
53 3QWI CUE 5.55556
54 1AE1 NAP 5.86081
55 2OEM 1AE 5.98592
56 3TDC 0EU 5.98592
57 5CKS GAL 5.98592
58 5OKL PAM 6.33803
59 2JC9 ADN 6.69014
60 3GCM 5GP 7.31707
61 5OFW 9TW 7.62332
62 4C2W ANP 7.69231
63 5JDC 6JP 8.09859
64 1ZX5 LFR 8.09859
65 1NXJ TLA 8.19672
66 2B4Q NAP 8.33333
67 5C2N NAG 8.33333
68 5TH5 MET 8.36502
69 3WMX NAD 8.4507
70 5N53 8NB 8.71795
71 3ELW GP3 8.80282
72 1VJT NAD 9.15493
73 3N8K D1X 9.30233
74 3EVF GTA 9.38628
75 2IDV M7G 9.60452
76 3BY9 SIN 10
77 5ZZ6 ADP 10.0962
78 3TKY N7I 10.2113
79 3HPY MCT 10.5634
80 3O94 NCA 10.9005
81 2Q28 ADP 11.2676
82 1IY8 NAD 11.6105
83 1J0I GLC GLC GLC 11.9718
84 5H9Q TD2 13.5484
85 3I7S PYR 13.7324
86 3KIH GDL 14.433
87 4WGF HX2 15.122
88 2Y69 CHD 20.2703
89 5X3R 7Y3 28.7805
Pocket No.: 5; Query (leader) PDB : 5YJF; Ligand: SAH; Similar sites found with APoc: 31
This union binding pocket(no: 5) in the query (biounit: 5yjf.bio4) has 34 residues
No: Leader PDB Ligand Sequence Similarity
1 4Y9T PA1 1.7341
2 2F5X ASP 1.76056
3 6BE0 COA 2.46479
4 1SQS TLA 2.47934
5 5GVR LMR 2.5641
6 4TQK NAG 2.8169
7 4I4S LAT 3.42466
8 1V6A TRE 3.52113
9 1NC4 DOF 3.72093
10 1NC2 DOE 3.72093
11 4NFE BEN 3.79747
12 4AZI OAN 4.57746
13 2OFW ADX 4.80769
14 2HYR BGC GLC 4.91803
15 2GUC MAN 4.91803
16 1M3U KPL 4.92424
17 4B3J COA 5.28169
18 1C3M MAN MAN 5.44218
19 3GXA MET 5.45455
20 4DE3 DN8 5.70342
21 4KQP GLN 6.03448
22 5ZZO FLC 6.46766
23 4B5W PYR 6.64062
24 1MXG ACR 6.69014
25 6MVU K4V 6.69014
26 3E4O SIN 7.39437
27 1GXS BEZ 8.22785
28 4AIA ADK 9.57447
29 3PMA SCR 10.3448
30 3A76 SPD 11.9318
31 5Y02 MXN 13.0841
Pocket No.: 6; Query (leader) PDB : 5YJF; Ligand: 8WO; Similar sites found with APoc: 32
This union binding pocket(no: 6) in the query (biounit: 5yjf.bio4) has 31 residues
No: Leader PDB Ligand Sequence Similarity
1 4JZ8 CIT 1.76056
2 1SQS TLA 2.47934
3 1UWK NAD 3.16901
4 1UWK URO 3.16901
5 4I4S LAT 3.42466
6 1V6A TRE 3.52113
7 2WSB NAD 3.54331
8 1NC4 DOF 3.72093
9 1NC2 DOE 3.72093
10 4NFE BEN 3.79747
11 4X1B MLI 4.22535
12 2QCX PF1 4.56274
13 5VN0 FAD 4.57746
14 1TO9 HMH 4.61538
15 2GUC MAN 4.91803
16 2HYR BGC GLC 4.91803
17 5FXD H7Y 4.92958
18 2PT9 2MH 4.92958
19 1C3M MAN MAN 5.44218
20 3GXA MET 5.45455
21 4DE3 DN8 5.70342
22 3IR1 MET 6.12245
23 5ZZO FLC 6.46766
24 4B5W PYR 6.64062
25 4MG8 27J 6.66667
26 1MXG ACR 6.69014
27 1K9J NAG MAN MAN MAN NAG 8.63309
28 4AIA ADK 9.57447
29 5Y02 MXN 13.0841
30 5AYI BGC 13.7324
31 2ZFZ ARG 22.7848
32 5NNT DPV 24.3243
Pocket No.: 7; Query (leader) PDB : 5YJF; Ligand: SAH; Similar sites found with APoc: 27
This union binding pocket(no: 7) in the query (biounit: 5yjf.bio2) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 1RZM PEP 2.11268
2 4KFU ACP 2.11268
3 1RRM APR 2.46479
4 2GN3 MAN 2.77778
5 2GN3 MMA 2.77778
6 6M7X JD7 2.8169
7 5X30 HCS 2.8169
8 5WAN URA 3.16901
9 5MB4 NDG 3.16901
10 3CYQ AMU 3.62319
11 5NM7 GLY 3.7594
12 1WUW TSU 4.44444
13 5V6F MAN BMA MAN 4.92958
14 6BK3 B2S 5.6338
15 1JT2 FER 5.97015
16 1YNS HPO 6.51341
17 4MG8 27J 6.66667
18 1T10 F6P 6.69014
19 2P7Q GG6 6.76692
20 4KVL PLM 7.04225
21 5CGM MAL 7.04225
22 4V3I ASP LEU THR ARG PRO 7.39437
23 3NHB ADP 7.39437
24 5YRV 5AD 8.4507
25 3TFC PEP 8.80282
26 2UZH IPE 10.9091
27 5W97 CHD 21.2766
Pocket No.: 8; Query (leader) PDB : 5YJF; Ligand: 8WO; Similar sites found with APoc: 29
This union binding pocket(no: 8) in the query (biounit: 5yjf.bio2) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 1RZM PEP 2.11268
2 4KFU ACP 2.11268
3 6BE0 COA 2.46479
4 1RRM APR 2.46479
5 2GN3 MAN 2.77778
6 2GN3 MMA 2.77778
7 4TQK NAG 2.8169
8 6M7X JD7 2.8169
9 5X30 HCS 2.8169
10 5WAN URA 3.16901
11 5MB4 NDG 3.16901
12 3CYQ AMU 3.62319
13 5NM7 GLY 3.7594
14 6BK3 B2S 5.6338
15 1JT2 FER 5.97015
16 4KQP GLN 6.03448
17 1YNS HPO 6.51341
18 1T10 F6P 6.69014
19 2P7Q GG6 6.76692
20 1SQL GUN 6.84932
21 4KVL PLM 7.04225
22 5CGM MAL 7.04225
23 4V3I ASP LEU THR ARG PRO 7.39437
24 2Q1A 2KT 7.39437
25 3NHB ADP 7.39437
26 5YRV 5AD 8.4507
27 3TFC PEP 8.80282
28 2UZH IPE 10.9091
29 5W97 CHD 21.2766
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