Receptor
PDB id Resolution Class Description Source Keywords
6DIM 1.81 Å EC: 3.1.4.- CRYSTAL STRUCTURE OF TDP1 CATALYTIC DOMAIN IN COMPLEX WITH Z FRAGMENT ZT1982 FROM COCKTAIL SOAK HOMO SAPIENS FRAGMENT-BASED DRUG DESIGN HYDROLASE-HYDROLASE INHIBITOR CO
Ref.: IDENTIFICATION OF A LIGAND BINDING HOT SPOT AND STR MOTIFS REPLICATING ASPECTS OF TYROSYL-DNA PHOSPHODI I (TDP1) PHOSPHORYL RECOGNITION BY CRYSTALLOGRAPHIC COCKTAIL SCREENING. NUCLEIC ACIDS RES. V. 47 10134 2019
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO B:702;
A:702;
B:705;
A:703;
B:704;
B:703;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
 submit data
62.068 C2 H6 O2 C(CO)...
GJP B:701;
A:701;
 Valid;
Valid;
 none;
none;
 submit data
189.167 C10 H7 N O3 c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6DJJ 1.74 Å EC: 3.1.4.- CRYSTAL STRUCTURE OF TDP1 CATALYTIC DOMAIN IN COMPLEX WITH C XZ532 HOMO SAPIENS FRAGMENT-BASED DRUG DESIGN HYDROLASE
Ref.: IDENTIFICATION OF A LIGAND BINDING HOT SPOT AND STR MOTIFS REPLICATING ASPECTS OF TYROSYL-DNA PHOSPHODI I (TDP1) PHOSPHORYL RECOGNITION BY CRYSTALLOGRAPHIC COCKTAIL SCREENING. NUCLEIC ACIDS RES. V. 47 10134 2019
Members (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 13 families.
1 6DJH - GNM C10 H6 Br N O3 c1cc2c(c(c....
2 6DJE - GNY C13 H13 N O3 CC(C)c1ccc....
3 6MJ5 - JTA C10 H6 N2 O5 c1cc2c(c(c....
4 6N17 ic50 = 1.01 mM K8Y C12 H11 N O7 c1cc(c(cc1....
5 6DIM - GJP C10 H7 N O3 c1ccc2c(c1....
6 6DJF - GNV C11 H7 N O5 c1cc2c(c(c....
7 6N19 ic50 = 0.96 mM K8V C13 H13 N O7 c1cc(c(cc1....
8 6DIE ic50 = 0.74 mM GHM C9 H6 O6 c1cc(c(cc1....
9 6DJI ic50 = 3.1 mM GOG C8 H6 O5 c1cc(c(c(c....
10 6DHU - GHM C9 H6 O6 c1cc(c(cc1....
11 6DJG - GNJ C10 H7 N O6 S c1cc2c(c(c....
12 6DJD ic50 = 7.2 mM GJP C10 H7 N O3 c1ccc2c(c1....
13 6DJJ ic50 = 80 uM GM7 C8 H7 N O4 c1cc(c(cc1....
14 6DIH ic50 = 1.9 mM GJS C8 H6 O5 c1cc(c(cc1....
70% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 12 families.
1 6DJH - GNM C10 H6 Br N O3 c1cc2c(c(c....
2 6DJE - GNY C13 H13 N O3 CC(C)c1ccc....
3 6MJ5 - JTA C10 H6 N2 O5 c1cc2c(c(c....
4 6N17 ic50 = 1.01 mM K8Y C12 H11 N O7 c1cc(c(cc1....
5 6DIM - GJP C10 H7 N O3 c1ccc2c(c1....
6 6DJF - GNV C11 H7 N O5 c1cc2c(c(c....
7 6N19 ic50 = 0.96 mM K8V C13 H13 N O7 c1cc(c(cc1....
8 6DIE ic50 = 0.74 mM GHM C9 H6 O6 c1cc(c(cc1....
9 6DJI ic50 = 3.1 mM GOG C8 H6 O5 c1cc(c(c(c....
10 6DHU - GHM C9 H6 O6 c1cc(c(cc1....
11 6DJG - GNJ C10 H7 N O6 S c1cc2c(c(c....
12 6DJD ic50 = 7.2 mM GJP C10 H7 N O3 c1ccc2c(c1....
13 6DJJ ic50 = 80 uM GM7 C8 H7 N O4 c1cc(c(cc1....
14 6DIH ic50 = 1.9 mM GJS C8 H6 O5 c1cc(c(cc1....
50% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 6DJH - GNM C10 H6 Br N O3 c1cc2c(c(c....
2 6DJE - GNY C13 H13 N O3 CC(C)c1ccc....
3 6MJ5 - JTA C10 H6 N2 O5 c1cc2c(c(c....
4 6N17 ic50 = 1.01 mM K8Y C12 H11 N O7 c1cc(c(cc1....
5 6DIM - GJP C10 H7 N O3 c1ccc2c(c1....
6 6DJF - GNV C11 H7 N O5 c1cc2c(c(c....
7 6N19 ic50 = 0.96 mM K8V C13 H13 N O7 c1cc(c(cc1....
8 6DIE ic50 = 0.74 mM GHM C9 H6 O6 c1cc(c(cc1....
9 6DJI ic50 = 3.1 mM GOG C8 H6 O5 c1cc(c(c(c....
10 6DHU - GHM C9 H6 O6 c1cc(c(cc1....
11 6DJG - GNJ C10 H7 N O6 S c1cc2c(c(c....
12 6DJD ic50 = 7.2 mM GJP C10 H7 N O3 c1ccc2c(c1....
13 6DJJ ic50 = 80 uM GM7 C8 H7 N O4 c1cc(c(cc1....
14 6DIH ic50 = 1.9 mM GJS C8 H6 O5 c1cc(c(cc1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GJP; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 GJP 1 1
2 GNV 0.461538 0.939394
Similar Ligands (3D)
Ligand no: 1; Ligand: GJP; Similar ligands found: 1063
No: Ligand Similarity coefficient
1 1HN 1.0000
2 4RU 1.0000
3 27B 1.0000
4 DNA 0.9783
5 GNM 0.9764
6 15N 0.9745
7 ANF 0.9742
8 E1T 0.9741
9 9ZE 0.9738
10 AA 0.9734
11 0JD 0.9734
12 AN3 0.9730
13 H5B 0.9728
14 ZYR 0.9675
15 PEY 0.9674
16 9CA 0.9654
17 THA 0.9644
18 SLS 0.9641
19 9FL 0.9640
20 6NT 0.9639
21 1IT 0.9624
22 68A 0.9622
23 1F1 0.9603
24 CH9 0.9601
25 0HO 0.9584
26 30G 0.9580
27 GDL 0.9578
28 6KT 0.9571
29 JAW 0.9570
30 BQ2 0.9567
31 8XL 0.9566
32 2ZM 0.9563
33 0HN 0.9562
34 8ZE 0.9562
35 2HU 0.9551
36 BZ2 0.9549
37 HA5 0.9546
38 DPT 0.9542
39 ESP 0.9541
40 ESX 0.9541
41 DRG 0.9538
42 N2I 0.9534
43 12T 0.9529
44 6QF 0.9525
45 5VL 0.9523
46 JG8 0.9522
47 5NI 0.9521
48 0FN 0.9519
49 3A9 0.9517
50 K97 0.9517
51 FDR 0.9513
52 0FK 0.9510
53 3NY 0.9509
54 JB8 0.9506
55 6NI 0.9503
56 JDN 0.9500
57 BCU 0.9497
58 NAG 0.9496
59 9R5 0.9494
60 ICB 0.9493
61 KMY 0.9489
62 3R4 0.9488
63 IAC 0.9488
64 5TY 0.9480
65 N1E 0.9477
66 ABI 0.9477
67 4BL 0.9475
68 6FZ 0.9472
69 SKF 0.9467
70 TTL 0.9465
71 BPY 0.9461
72 3J8 0.9460
73 8HC 0.9458
74 4BY 0.9457
75 SNO 0.9457
76 KYA 0.9453
77 2K8 0.9453
78 2FQ 0.9450
79 ANC 0.9449
80 PJW 0.9435
81 GO2 0.9427
82 MQN 0.9424
83 PH2 0.9414
84 N0Z 0.9412
85 X0U 0.9412
86 BEA 0.9412
87 NDG 0.9406
88 SKA 0.9400
89 8MO 0.9399
90 2KA 0.9398
91 428 0.9398
92 KDV 0.9395
93 4JQ 0.9395
94 2HC 0.9392
95 3ZB 0.9392
96 6FB 0.9386
97 J9Q 0.9386
98 3PF 0.9382
99 12Q 0.9380
100 9FE 0.9379
101 C2Y 0.9379
102 R9Y 0.9379
103 94W 0.9378
104 4NB 0.9377
105 92P 0.9374
106 M4E 0.9371
107 1A7 0.9370
108 LQ2 0.9370
109 D48 0.9370
110 5QY 0.9368
111 7W1 0.9367
112 UNJ 0.9363
113 344 0.9363
114 KTW 0.9362
115 XHP 0.9357
116 15E 0.9352
117 KJH 0.9349
118 0N7 0.9349
119 0TU 0.9346
120 TIY 0.9345
121 ESI 0.9345
122 B62 0.9345
123 97T 0.9343
124 S0E 0.9341
125 BNX 0.9341
126 6ME 0.9339
127 MAJ 0.9335
128 LDR 0.9335
129 4I8 0.9333
130 HHS 0.9329
131 BA5 0.9328
132 AJY 0.9324
133 CLZ 0.9321
134 E1K 0.9316
135 MSR 0.9316
136 9UL 0.9316
137 N2M 0.9315
138 BZJ 0.9315
139 5QX 0.9311
140 0FO 0.9311
141 HHR 0.9310
142 3QV 0.9309
143 BZ3 0.9307
144 HQD 0.9306
145 CWJ 0.9301
146 4AA 0.9301
147 1QP 0.9300
148 V1T 0.9299
149 HQT 0.9298
150 2LY 0.9295
151 A7H 0.9293
152 DQU 0.9293
153 4YO 0.9292
154 BGC 0.9291
155 4TU 0.9288
156 5RO 0.9288
157 G3E 0.9286
158 5XC 0.9284
159 4BZ 0.9284
160 PXL 0.9283
161 FQX 0.9281
162 4KL 0.9281
163 ST2 0.9280
164 3VX 0.9280
165 AJV 0.9279
166 RNO 0.9278
167 DNF 0.9278
168 BPN 0.9278
169 44W 0.9277
170 537 0.9277
171 AZ9 0.9276
172 2FY 0.9274
173 M2K 0.9273
174 PRF 0.9272
175 OTW 0.9271
176 8NX 0.9269
177 363 0.9268
178 MD6 0.9268
179 9AP 0.9266
180 54X 0.9266
181 SE2 0.9265
182 5OB 0.9262
183 L14 0.9261
184 2BG 0.9260
185 MVN 0.9259
186 ANN 0.9258
187 J6W 0.9258
188 AP4 0.9257
189 E7S 0.9252
190 5GT 0.9251
191 N91 0.9249
192 8WO 0.9249
193 2O6 0.9248
194 6VD 0.9248
195 0BP 0.9247
196 S7J 0.9246
197 PNZ 0.9246
198 JTH 0.9246
199 N8Y 0.9245
200 EVF 0.9244
201 NID 0.9242
202 EUE 0.9241
203 36E 0.9237
204 MS9 0.9237
205 4WL 0.9236
206 9KZ 0.9234
207 EA1 0.9230
208 QX4 0.9230
209 INE 0.9229
210 PPY 0.9228
211 VK3 0.9228
212 J5I 0.9227
213 86J 0.9221
214 44V 0.9220
215 AMH 0.9217
216 M5H 0.9215
217 0F9 0.9214
218 SYA 0.9212
219 FBF 0.9211
220 NQ 0.9211
221 ODO 0.9210
222 ICO 0.9210
223 9BF 0.9209
224 EN1 0.9209
225 P9E 0.9207
226 JP2 0.9206
227 5LA 0.9206
228 XIY 0.9206
229 IOP 0.9205
230 EXD 0.9204
231 IV2 0.9203
232 TGX 0.9202
233 E5X 0.9202
234 CTL 0.9201
235 HKD 0.9201
236 KJU 0.9200
237 MR1 0.9199
238 IOS 0.9197
239 SYV 0.9196
240 6RQ 0.9194
241 H42 0.9194
242 S8A 0.9192
243 ZEC 0.9191
244 39O 0.9190
245 5RN 0.9188
246 F31 0.9188
247 FBB 0.9187
248 ZZZ 0.9186
249 UFO 0.9186
250 4P5 0.9183
251 61M 0.9182
252 K2T 0.9181
253 5WU 0.9180
254 JND 0.9180
255 JLZ 0.9180
256 Z5P 0.9179
257 92K 0.9179
258 NGA 0.9177
259 PYQ 0.9177
260 37T 0.9177
261 F9Y 0.9176
262 TT4 0.9174
263 3AE 0.9173
264 259 0.9172
265 TTY 0.9172
266 03V 0.9172
267 HBO 0.9171
268 BNL 0.9170
269 CK2 0.9166
270 CN0 0.9165
271 RXA 0.9165
272 GF4 0.9164
273 SNU 0.9163
274 FA0 0.9163
275 1M2 0.9162
276 1L5 0.9162
277 B56 0.9161
278 INO 0.9161
279 1VK 0.9159
280 LI6 0.9159
281 TSR 0.9157
282 HRM 0.9157
283 52C 0.9156
284 BPU 0.9155
285 1KP 0.9152
286 TOF 0.9152
287 BK9 0.9150
288 OW7 0.9150
289 BIK 0.9148
290 9KT 0.9148
291 PD2 0.9148
292 DHB 0.9148
293 4FS 0.9147
294 2HQ 0.9146
295 F4E 0.9145
296 A2G 0.9144
297 GCU 0.9144
298 DIN 0.9143
299 209 0.9143
300 CKA 0.9143
301 RD4 0.9141
302 28N 0.9141
303 PQ0 0.9140
304 L22 0.9140
305 ES5 0.9139
306 0FR 0.9139
307 4ZA 0.9138
308 TMG 0.9136
309 KTJ 0.9135
310 PFL 0.9133
311 K4V 0.9132
312 OCH 0.9132
313 N3W 0.9127
314 FF2 0.9125
315 MQG 0.9124
316 QIV 0.9123
317 2AQ 0.9123
318 XCG 0.9122
319 HDL 0.9121
320 COU 0.9121
321 M78 0.9120
322 PMP 0.9120
323 X48 0.9120
324 FHB 0.9119
325 2CZ 0.9117
326 LR5 0.9117
327 TZF 0.9116
328 PQK 0.9113
329 CFA 0.9112
330 8W9 0.9110
331 VNL 0.9110
332 CPZ 0.9109
333 S60 0.9107
334 KW8 0.9105
335 XDK 0.9102
336 CHB 0.9102
337 ST3 0.9101
338 5NS 0.9101
339 A5E 0.9100
340 3DM 0.9100
341 C9E 0.9098
342 OQC 0.9098
343 DOB 0.9097
344 4LW 0.9097
345 SN4 0.9096
346 PRL 0.9096
347 HQJ 0.9096
348 3MG 0.9095
349 A29 0.9093
350 BGU 0.9093
351 BHA 0.9092
352 BDP 0.9091
353 KUF 0.9091
354 NNO 0.9089
355 P9P 0.9089
356 4NM 0.9088
357 4ME 0.9088
358 MRW 0.9087
359 JB5 0.9087
360 NOK 0.9086
361 A7W 0.9085
362 Y3L 0.9084
363 4A3 0.9083
364 E3D 0.9081
365 4M0 0.9081
366 4NC 0.9080
367 3R6 0.9078
368 6TZ 0.9077
369 GLC 0.9076
370 5NE 0.9076
371 LL1 0.9074
372 TSS 0.9073
373 IWT 0.9072
374 5CU 0.9071
375 N2Z 0.9069
376 XAZ 0.9067
377 HNT 0.9066
378 3HM 0.9066
379 3XR 0.9065
380 GVG 0.9065
381 EYV 0.9062
382 HX4 0.9062
383 5GU 0.9058
384 5WV 0.9057
385 ET2 0.9056
386 JRB 0.9055
387 BHQ 0.9054
388 ITE 0.9054
389 C1M 0.9054
390 JU2 0.9053
391 5NU 0.9052
392 BP7 0.9051
393 0W1 0.9050
394 G12 0.9050
395 5WY 0.9049
396 AY4 0.9048
397 6BL 0.9046
398 93K 0.9046
399 LNR 0.9044
400 BBK 0.9044
401 ZB1 0.9043
402 NOY 0.9043
403 L99 0.9043
404 MEW 0.9043
405 PDC 0.9043
406 MUA 0.9042
407 C53 0.9040
408 4NZ 0.9040
409 PIM 0.9040
410 SRO 0.9040
411 SNG 0.9039
412 8WT 0.9036
413 ROI 0.9036
414 7O4 0.9035
415 NOJ 0.9034
416 KJ5 0.9034
417 SG2 0.9033
418 NDH 0.9033
419 LZ2 0.9031
420 YZM 0.9029
421 2FX 0.9029
422 ONR 0.9029
423 X8D 0.9029
424 APS 0.9029
425 3VS 0.9029
426 0P6 0.9029
427 LT2 0.9029
428 3GQ 0.9028
429 ZSP 0.9026
430 ES2 0.9024
431 ASO 0.9023
432 IFL 0.9018
433 L46 0.9018
434 B57 0.9018
435 AJ2 0.9018
436 DX3 0.9017
437 K3Q 0.9016
438 HDH 0.9016
439 2JK 0.9016
440 PIY 0.9016
441 W81 0.9015
442 LOG 0.9014
443 URC 0.9014
444 KYN 0.9013
445 TYL 0.9013
446 7VP 0.9012
447 KF5 0.9012
448 8CM 0.9011
449 4MU 0.9011
450 ES7 0.9011
451 IHB 0.9011
452 92G 0.9010
453 67N 0.9010
454 E7Z 0.9009
455 XQ0 0.9008
456 F4K 0.9007
457 FLV 0.9007
458 S0G 0.9005
459 JBZ 0.9004
460 BTY 0.9003
461 2EC 0.9001
462 BZE 0.8999
463 M6Z 0.8998
464 4V2 0.8998
465 ARP 0.8998
466 AQO 0.8998
467 2QC 0.8998
468 BNT 0.8998
469 7B3 0.8997
470 AM4 0.8996
471 657 0.8995
472 4HC 0.8995
473 GO8 0.8994
474 CLW 0.8994
475 M5K 0.8994
476 GZL 0.8994
477 8NB 0.8993
478 EVA 0.8992
479 VGD 0.8992
480 QBK 0.8992
481 ALE 0.8991
482 TXW 0.8991
483 0J4 0.8990
484 M1Q 0.8989
485 NLA 0.8989
486 FHC 0.8989
487 MYJ 0.8988
488 4AB 0.8987
489 36R 0.8987
490 3VQ 0.8985
491 2HO 0.8985
492 R20 0.8983
493 KKN 0.8983
494 QSB 0.8983
495 UAN 0.8982
496 SOE 0.8982
497 CC5 0.8981
498 GCS 0.8978
499 I3E 0.8977
500 X11 0.8977
501 A7N 0.8976
502 4Z4 0.8975
503 1P8 0.8975
504 CWS 0.8975
505 APZ 0.8974
506 8S0 0.8974
507 K7H 0.8973
508 4CM 0.8973
509 R8V 0.8973
510 GXY 0.8971
511 BIO 0.8971
512 GDE 0.8971
513 8G0 0.8969
514 173 0.8969
515 DNC 0.8969
516 G3F 0.8969
517 226 0.8968
518 J9W 0.8967
519 GVY 0.8966
520 2GQ 0.8966
521 TWO 0.8966
522 Q71 0.8965
523 5VM 0.8964
524 4JT 0.8964
525 CFF 0.8963
526 KGK 0.8961
527 JTA 0.8959
528 K44 0.8959
529 H4B 0.8959
530 SHA 0.8958
531 0XT 0.8958
532 DEW 0.8957
533 H33 0.8957
534 AZ8 0.8957
535 QMS 0.8955
536 HBI 0.8953
537 H2B 0.8953
538 M6N 0.8953
539 KJY 0.8952
540 VXX 0.8951
541 SKM 0.8951
542 G2F 0.8950
543 M1A 0.8950
544 ISN 0.8950
545 PFB 0.8950
546 MAG 0.8949
547 F2W 0.8948
548 FDB 0.8948
549 4XF 0.8947
550 Q77 0.8946
551 ZHA 0.8945
552 FUD 0.8945
553 2A9 0.8944
554 PE0 0.8944
555 2AK 0.8944
556 XX2 0.8943
557 0OK 0.8943
558 ASC 0.8941
559 I3A 0.8939
560 VC3 0.8938
561 4NS 0.8937
562 DEE 0.8937
563 RH1 0.8935
564 M3H 0.8935
565 N4E 0.8935
566 9TW 0.8935
567 L5V 0.8935
568 B55 0.8934
569 5VJ 0.8933
570 PHB 0.8932
571 NCT 0.8931
572 JF2 0.8930
573 GCB 0.8930
574 549 0.8930
575 PLP 0.8930
576 DDU 0.8929
577 ZYQ 0.8929
578 EV2 0.8928
579 Z13 0.8926
580 OA3 0.8926
581 HIS 0.8926
582 MPV 0.8925
583 8TX 0.8924
584 I4D 0.8922
585 75K 0.8922
586 JF1 0.8921
587 GNY 0.8919
588 K68 0.8919
589 2H5 0.8918
590 717 0.8917
591 K32 0.8917
592 5GV 0.8916
593 4NP 0.8916
594 OVM 0.8916
595 RM1 0.8915
596 Q24 0.8915
597 SJK 0.8915
598 EWG 0.8913
599 7MW 0.8911
600 DMD 0.8910
601 3IT 0.8910
602 5JQ 0.8909
603 E3X 0.8909
604 AZM 0.8908
605 3MB 0.8907
606 9FH 0.8906
607 J9N 0.8906
608 505 0.8905
609 O2A 0.8905
610 ZME 0.8905
611 6ZW 0.8905
612 EE8 0.8904
613 SQ4 0.8903
614 7W4 0.8903
615 6E8 0.8903
616 2GS 0.8901
617 G14 0.8901
618 3HA 0.8900
619 PHH 0.8899
620 DK1 0.8897
621 7ZE 0.8896
622 TEP 0.8895
623 IQ5 0.8895
624 4JC 0.8893
625 ZZA 0.8892
626 MP5 0.8891
627 MAQ 0.8891
628 0NX 0.8890
629 1Z6 0.8890
630 7VS 0.8890
631 2F6 0.8888
632 2UZ 0.8888
633 HC4 0.8888
634 PRZ 0.8886
635 4HM 0.8886
636 36Y 0.8885
637 Y0V 0.8885
638 NPO 0.8884
639 7FU 0.8883
640 B60 0.8883
641 LP8 0.8882
642 TCA 0.8882
643 PBA 0.8880
644 DRL 0.8880
645 L7T 0.8879
646 ZVO 0.8879
647 78U 0.8878
648 DHC 0.8878
649 QPR 0.8878
650 3VW 0.8877
651 GC2 0.8877
652 ADA 0.8876
653 JA8 0.8875
654 M4S 0.8874
655 YTX 0.8872
656 9H2 0.8872
657 X0W 0.8870
658 PO6 0.8869
659 PXM 0.8869
660 TRP 0.8869
661 TCR 0.8869
662 795 0.8868
663 3W8 0.8868
664 GF1 0.8868
665 AX7 0.8867
666 QQQ 0.8867
667 HBD 0.8866
668 CNI 0.8865
669 2F8 0.8863
670 82I 0.8863
671 3ID 0.8861
672 MO8 0.8860
673 F1A 0.8860
674 56D 0.8859
675 QUS 0.8858
676 E7R 0.8858
677 GTR 0.8858
678 DHK 0.8857
679 2ZQ 0.8854
680 3Z8 0.8854
681 1WC 0.8854
682 PAB 0.8853
683 86L 0.8852
684 JWB 0.8851
685 4HB 0.8851
686 LDP 0.8851
687 1U6 0.8851
688 7WR 0.8850
689 LEL 0.8849
690 6HO 0.8848
691 NGT 0.8847
692 BVA 0.8846
693 7MX 0.8845
694 JCZ 0.8844
695 4MA 0.8843
696 20J 0.8842
697 8D6 0.8841
698 ABV 0.8841
699 PBZ 0.8841
700 XDE 0.8838
701 XFE 0.8837
702 GZ2 0.8837
703 RA7 0.8836
704 GSY 0.8835
705 P80 0.8835
706 AMR 0.8834
707 PHE 0.8833
708 J9T 0.8832
709 7HQ 0.8831
710 4MB 0.8830
711 ODK 0.8829
712 GAL 0.8828
713 826 0.8828
714 WS7 0.8828
715 X0V 0.8826
716 DPZ 0.8825
717 OW4 0.8824
718 3N1 0.8823
719 L1Q 0.8821
720 6X9 0.8821
721 KT7 0.8821
722 BM3 0.8820
723 4XV 0.8820
724 OVP 0.8819
725 MNS 0.8819
726 HHI 0.8819
727 9TF 0.8817
728 11S 0.8817
729 4AN 0.8817
730 6J9 0.8816
731 5F5 0.8816
732 49O 0.8816
733 CTS 0.8815
734 JAE 0.8815
735 SHG 0.8815
736 AES 0.8815
737 IL5 0.8814
738 DBH 0.8814
739 5JL 0.8813
740 IPD 0.8812
741 VM1 0.8812
742 QMR 0.8811
743 B4O 0.8810
744 C82 0.8810
745 GCW 0.8808
746 4FH 0.8808
747 DC5 0.8807
748 1Y6 0.8806
749 5V7 0.8806
750 L1O 0.8805
751 ENO 0.8805
752 F02 0.8802
753 HNL 0.8802
754 HNK 0.8802
755 GHM 0.8801
756 069 0.8801
757 Z82 0.8800
758 4SX 0.8799
759 IPB 0.8798
760 NSG 0.8797
761 1QV 0.8796
762 NGW 0.8795
763 LGC 0.8794
764 0J5 0.8794
765 OTR 0.8794
766 36M 0.8793
767 B1J 0.8793
768 Q6T 0.8792
769 P7Y 0.8790
770 BHS 0.8790
771 PH3 0.8790
772 QSH 0.8790
773 2J2 0.8788
774 7MU 0.8788
775 3F0 0.8788
776 KIB 0.8787
777 B5D 0.8787
778 5AD 0.8785
779 J38 0.8785
780 7NI 0.8784
781 2J1 0.8783
782 XM0 0.8783
783 A5P 0.8782
784 G5V 0.8780
785 B53 0.8780
786 WSD 0.8780
787 5SJ 0.8779
788 5E5 0.8777
789 K22 0.8777
790 3M0 0.8777
791 174 0.8776
792 IQZ 0.8776
793 I2E 0.8774
794 FGZ 0.8774
795 SOR 0.8773
796 PUE 0.8773
797 TBS 0.8773
798 JAH 0.8772
799 XIZ 0.8772
800 7MK 0.8770
801 P72 0.8770
802 9NB 0.8769
803 MXD 0.8769
804 TYR 0.8768
805 PZM 0.8768
806 680 0.8767
807 QX2 0.8766
808 B52 0.8766
809 FZM 0.8766
810 PX7 0.8766
811 7I2 0.8766
812 D3G 0.8763
813 MUR 0.8760
814 PA1 0.8759
815 A5H 0.8758
816 XM5 0.8758
817 6DP 0.8757
818 H4N 0.8756
819 UEG 0.8756
820 7ME 0.8756
821 CXH 0.8755
822 1P7 0.8755
823 X0T 0.8753
824 5OO 0.8753
825 NPA 0.8749
826 K25 0.8749
827 8U3 0.8745
828 NRA 0.8745
829 1DR 0.8745
830 AC6 0.8744
831 BZX 0.8744
832 HJ7 0.8742
833 QWN 0.8740
834 X05 0.8739
835 32X 0.8739
836 ES9 0.8738
837 WS6 0.8737
838 4XS 0.8737
839 EUG 0.8734
840 1XA 0.8734
841 KLK 0.8733
842 GCV 0.8731
843 8XQ 0.8731
844 78Y 0.8730
845 MS0 0.8730
846 QBP 0.8729
847 EKZ 0.8729
848 4FA 0.8728
849 Q02 0.8727
850 KOJ 0.8726
851 II4 0.8726
852 6R8 0.8724
853 FK1 0.8723
854 2MI 0.8723
855 K82 0.8722
856 KBZ 0.8722
857 9PY 0.8722
858 R2P 0.8722
859 LUM 0.8721
860 M0W 0.8720
861 3Y7 0.8720
862 2D0 0.8720
863 FYU 0.8719
864 IFP 0.8719
865 JBK 0.8719
866 42C 0.8718
867 LR8 0.8718
868 42A 0.8717
869 6L6 0.8717
870 DBJ 0.8716
871 LAO 0.8714
872 GAF 0.8714
873 P92 0.8713
874 XXP 0.8713
875 TH7 0.8713
876 HHH 0.8712
877 AHR 0.8712
878 JY4 0.8711
879 67X 0.8710
880 8IG 0.8710
881 270 0.8709
882 5B1 0.8708
883 2WU 0.8708
884 DNQ 0.8707
885 ZXD 0.8706
886 BY5 0.8705
887 CTE 0.8705
888 TZM 0.8705
889 AKH 0.8705
890 2LW 0.8703
891 5MI 0.8703
892 EGR 0.8702
893 RVE 0.8702
894 QWW 0.8700
895 5H1 0.8700
896 LFN 0.8700
897 091 0.8700
898 NVU 0.8699
899 HMH 0.8699
900 SWA 0.8698
901 39Z 0.8698
902 AX3 0.8698
903 42J 0.8697
904 S0D 0.8697
905 DE5 0.8696
906 14O 0.8696
907 5WT 0.8696
908 2BX 0.8696
909 UFV 0.8696
910 VUP 0.8695
911 NSP 0.8695
912 YH7 0.8694
913 8H8 0.8693
914 S98 0.8692
915 54Z 0.8691
916 BSP 0.8690
917 F60 0.8690
918 MAN 0.8690
919 CIT 0.8690
920 MFZ 0.8689
921 7B4 0.8686
922 582 0.8685
923 Z21 0.8683
924 LKA 0.8683
925 0W8 0.8682
926 MOK 0.8681
927 9DG 0.8679
928 YRL 0.8678
929 Q7A 0.8677
930 QXW 0.8676
931 DHR 0.8673
932 64C 0.8673
933 2PK 0.8673
934 21D 0.8671
935 MQB 0.8671
936 HNQ 0.8671
937 2PV 0.8671
938 LZM 0.8670
939 F5C 0.8669
940 FE DB1 0.8667
941 M0Q 0.8667
942 HLD 0.8666
943 ADZ 0.8665
944 GCO 0.8663
945 1ZC 0.8663
946 6HP 0.8663
947 1LQ 0.8660
948 FA1 0.8659
949 NTZ 0.8659
950 2K4 0.8658
951 JVN 0.8658
952 HCI 0.8657
953 6AI 0.8657
954 M1H 0.8656
955 GUN 0.8656
956 1AL 0.8655
957 MHK 0.8654
958 WV7 0.8654
959 D07 0.8653
960 NDD 0.8653
961 GLA 0.8653
962 5RG 0.8653
963 Q88 0.8652
964 K17 0.8651
965 YE7 0.8651
966 NGO 0.8650
967 BZQ 0.8650
968 PFF 0.8650
969 8NY 0.8650
970 0SY 0.8650
971 QMP 0.8649
972 X04 0.8648
973 HHA 0.8648
974 ES0 0.8648
975 AZA 0.8648
976 1NP 0.8648
977 RKV 0.8646
978 EMO 0.8643
979 M1E 0.8642
980 5MB 0.8640
981 LIP 0.8640
982 SWX 0.8639
983 HA7 0.8639
984 AU8 0.8638
985 XAN 0.8637
986 6SD 0.8635
987 BOA 0.8635
988 V55 0.8633
989 X09 0.8633
990 GTQ 0.8632
991 AMS 0.8631
992 141 0.8631
993 M45 0.8630
994 5F8 0.8630
995 ISZ 0.8630
996 1SQ 0.8629
997 CWM 0.8628
998 NDM 0.8624
999 MPK 0.8623
1000 7A2 0.8622
1001 TSU 0.8622
1002 BHO 0.8622
1003 JR2 0.8621
1004 FLC 0.8620
1005 CCV 0.8619
1006 PHU 0.8618
1007 WUB 0.8617
1008 ZRK 0.8617
1009 AAN 0.8616
1010 DHY 0.8613
1011 CFI 0.8613
1012 39A 0.8613
1013 P81 0.8612
1014 4FF 0.8612
1015 1XM 0.8612
1016 NIZ 0.8609
1017 K34 0.8609
1018 GXL 0.8606
1019 8GK 0.8606
1020 2AL 0.8605
1021 AJG 0.8605
1022 NBG 0.8604
1023 22L 0.8604
1024 RUY 0.8602
1025 0UL 0.8602
1026 0GZ 0.8601
1027 X6X 0.8597
1028 K37 0.8591
1029 6AP 0.8591
1030 DUR 0.8589
1031 EMZ 0.8587
1032 JGB 0.8583
1033 QIC 0.8582
1034 DXK 0.8581
1035 F69 0.8580
1036 9LI 0.8579
1037 DGJ 0.8578
1038 SJ5 0.8578
1039 AEF 0.8572
1040 FCR 0.8570
1041 4LV 0.8569
1042 FA3 0.8567
1043 XQG 0.8565
1044 5M0 0.8565
1045 06B 0.8564
1046 54G 0.8564
1047 TXQ 0.8564
1048 THM 0.8562
1049 FBS 0.8556
1050 SW7 0.8553
1051 XI7 0.8552
1052 L13 0.8544
1053 K5W 0.8541
1054 F0J 0.8539
1055 STT 0.8539
1056 GZQ 0.8536
1057 1GN 0.8536
1058 TIU 0.8536
1059 HX3 0.8528
1060 KP2 0.8526
1061 5FL 0.8525
1062 XXG 0.8516
1063 PIQ 0.8507
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6DJJ; Ligand: GM7; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6djj.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 6DJJ; Ligand: GM7; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 6djj.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
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