-->
Receptor
PDB id Resolution Class Description Source Keywords
6F7L 2.5 Å EC: 1.-.-.- CRYSTAL STRUCTURE OF LKCE R326Q MUTANT IN COMPLEX WITH ITS S STREPTOMYCES ROCHEI AMINE OXYDASE CYCLASE POST-PKS ENZYME TAYLORING ENZYME FLAVOPROTEIN
Ref.: INSIGHTS INTO A DUAL FUNCTION AMIDE OXIDASE/MACROCY FROM LANKACIDIN BIOSYNTHESIS. NAT COMMUN V. 9 3998 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT B:504;
B:505;
B:503;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
59.044 C2 H3 O2 CC(=O...
GOL A:506;
B:509;
B:508;
B:507;
B:511;
B:510;
A:505;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
CA A:502;
B:502;
A:503;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
40.078 Ca [Ca+2...
CWH B:506;
A:504;
Valid;
Valid;
none;
none;
submit data
515.68 C27 H49 N O8 C[C@@...
FAD A:501;
B:501;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6F7L 2.5 Å EC: 1.-.-.- CRYSTAL STRUCTURE OF LKCE R326Q MUTANT IN COMPLEX WITH ITS S STREPTOMYCES ROCHEI AMINE OXYDASE CYCLASE POST-PKS ENZYME TAYLORING ENZYME FLAVOPROTEIN
Ref.: INSIGHTS INTO A DUAL FUNCTION AMIDE OXIDASE/MACROCY FROM LANKACIDIN BIOSYNTHESIS. NAT COMMUN V. 9 3998 2018
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 318 families.
1 6F7L - CWH C27 H49 N O8 C[C@@H]1[C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 280 families.
1 6F7L - CWH C27 H49 N O8 C[C@@H]1[C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 6F7L - CWH C27 H49 N O8 C[C@@H]1[C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: CWH; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 CWH 1 1
Ligand no: 2; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6F7L; Ligand: FAD; Similar sites found with APoc: 921
This union binding pocket(no: 1) in the query (biounit: 6f7l.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 5C2N NAG None
2 6CS9 PIO None
3 1PNO NAP 1.11111
4 2RGH FAD 1.13122
5 2RGO FAD 1.13122
6 4L8V NAP 1.18694
7 1X14 NAD 1.24688
8 4RW3 SHV 1.3245
9 6D6Y SAH 1.35747
10 3OJO NAD 1.39211
11 2DPM SAM 1.40845
12 3GFB NAD 1.42857
13 5AOV NAP 1.4881
14 3VSE SAH 1.50754
15 5KOK SAH 1.51134
16 5W75 GDP 1.53061
17 3DMH SAM 1.5748
18 4U8P FDA 1.58371
19 4U8P UDP 1.58371
20 2A8X FAD 1.58371
21 2CDU FAD 1.58371
22 4M52 FAD 1.58371
23 5DNK SAH 1.58371
24 4MIG G3F 1.58371
25 4M52 M52 1.58371
26 2CDU ADP 1.58371
27 1GUZ NAD 1.6129
28 4KRI SAH 1.61663
29 5JE0 SAH 1.61943
30 5JE0 AZ8 1.61943
31 2JJQ SAH 1.64706
32 3A25 SAM 1.66113
33 2AOT SAH 1.71233
34 5ZI2 NAD 1.73913
35 5ZI2 ADP 1.73913
36 3QPB R1P 1.77305
37 1CF2 NAP 1.78042
38 4D04 FAD 1.80995
39 4D04 NAP 1.80995
40 2DKH 3HB 1.80995
41 2DKH FAD 1.80995
42 3HQP FDP 1.80995
43 1YQZ FAD 1.82648
44 5W7Q GDP 1.87668
45 3K56 IS3 1.8797
46 6HKE LMR 1.88679
47 5Z21 NAI 1.95531
48 5I39 FAD 1.96078
49 1YKF NAP 1.98864
50 1YP4 ADP 1.99557
51 5DX8 SFG 2.00573
52 5DWQ SFG 2.00573
53 5UR0 NAD 2.00573
54 5DXA SFG 2.00573
55 5DX1 SFG 2.00573
56 5DX0 SFG 2.00573
57 3Q3C NAD 2.00669
58 3FIU AMP 2.00803
59 1GPE FAD 2.0362
60 3QVP FAD 2.0362
61 5ZYN FAD 2.0362
62 3E1T FAD 2.0362
63 4AT0 FAD 2.0362
64 1BZL FAD 2.0362
65 3BRE C2E 2.0362
66 2I3G NAP 2.0362
67 1BZL GCG 2.0362
68 1GZ4 ATP 2.0362
69 4HXY NDP 2.0362
70 1G51 AMP 2.0362
71 5AHW CMP 2.04082
72 3HJ1 UTP 2.06718
73 3NJ4 NAD 2.06897
74 3NJ4 AFX 2.06897
75 3V1Y NAD 2.07715
76 3B8I OXL 2.09059
77 4Z0H NAD 2.09581
78 1DSS NAD 2.1021
79 1ZQ9 SAM 2.10526
80 3RK0 AMP 2.1097
81 1SOW NAD 2.13415
82 1KYQ NAD 2.18978
83 1NW5 SAM 2.19436
84 3FUU ADN 2.21402
85 4TQK NAG 2.21675
86 3QWI NAP 2.22222
87 3QWI CUE 2.22222
88 2RGJ FAD 2.23881
89 5OFW 9TW 2.24215
90 2YY7 NAD 2.24359
91 5BW4 SAM 2.24719
92 1FEC FAD 2.26244
93 1O0S NAI 2.26244
94 1PN0 FAD 2.26244
95 1PN0 IPH 2.26244
96 1VI2 NAD 2.26244
97 2ZJ1 ARJ 2.26244
98 4EDF UPG 2.26244
99 2ZJ1 NAD 2.26244
100 4ISS TAR 2.26244
101 1H5Q NAP 2.26415
102 4NEC SAH 2.27273
103 1KEV NDP 2.2792
104 3MQ2 SAH 2.29358
105 3WBF NAP 2.29508
106 5H81 NAP 2.31362
107 4DKX GDP 2.31481
108 4JK3 NAD 2.3166
109 4J4H NAI 2.3166
110 4J4H 1J1 2.3166
111 5TWB FAD 2.32558
112 2VT3 ATP 2.32558
113 5Y8L NAD 2.37288
114 5Y8L HUI 2.37288
115 5ZXD ATP 2.38095
116 1CER NAD 2.41692
117 1F8F NAD 2.42588
118 2HQM FAD 2.48869
119 2NVK FAD 2.48869
120 2IZ1 ATR 2.48869
121 4TXI FAD 2.48869
122 2NVK NAP 2.48869
123 2BRY FAD 2.48869
124 1COY FAD 2.48869
125 6FP4 FAD 2.48869
126 4C4A SAH 2.48869
127 6FP4 E1T 2.48869
128 1GQ2 NAP 2.48869
129 1COY AND 2.48869
130 1A5Z NAD 2.50784
131 1HKU NAD 2.51397
132 5CGE 51F 2.52708
133 2DC1 NAD 2.54237
134 4DMG SAM 2.54453
135 3GGO ENO 2.54777
136 3GGO NAI 2.54777
137 5N0J FAD 2.5641
138 5N53 8NB 2.5641
139 5KKA 6V0 2.5641
140 1ZK7 FAD 2.56959
141 3M89 GSP 2.57611
142 3VPH NAD 2.58065
143 3VPH OXM 2.58065
144 2XVF FAD 2.58621
145 1V1A KDG 2.589
146 1RYI GOA 2.6178
147 1RYI FAD 2.6178
148 5F8F SFG 2.65252
149 5MPT SAH 2.657
150 3A06 NDP 2.65957
151 2EV9 NAP 2.6616
152 2EV9 SKM 2.6616
153 4RQU NAD 2.66667
154 1GEE NAD 2.68199
155 3DUW SAH 2.69058
156 4ZVV NAD 2.71084
157 1HDG NAD 2.71084
158 4ZVV GN0 2.71084
159 4J56 FAD 2.71493
160 1NAA 6FA 2.71493
161 1NAA ABL 2.71493
162 1ZGS XMM 2.71493
163 5UAO FAD 2.71493
164 1GOJ ADP 2.71493
165 5FA5 MTA 2.71493
166 3IWJ NAD 2.71493
167 1UWK NAD 2.71493
168 1UWK URO 2.71493
169 5H6S HDH 2.71493
170 1V8B NAD 2.71493
171 5WP4 SAH 2.71493
172 1ZGA SAH 2.71493
173 4LWP SAH 2.71739
174 1GEG NAD 2.73438
175 1BG2 ADP 2.76923
176 1UKG MMA 2.77778
177 2GND MAN MMA 2.77778
178 1Q8P MAN MMA 2.77778
179 2PHF MAN MAN 2.77778
180 2PHX MAN MAN 2.77778
181 2PHW MAN MAN 2.77778
182 1Q8V MAN MAN 2.77778
183 1Q8S MAN MMA 2.77778
184 2PHR MAN MAN 2.77778
185 1Q8Q MAN MMA 2.77778
186 2PHF MAN MAN BMA MAN 2.77778
187 2PHU MAN MAN 2.77778
188 2PHR MAN MAN BMA MAN 2.77778
189 2GND MAN 2.77778
190 2PHT MAN MAN MAN 2.77778
191 2PHT MAN MAN MAN BMA MAN 2.77778
192 2GN3 MAN 2.77778
193 2AUY NAG MAN MMA 2.77778
194 2AR6 NAG MAN 2.77778
195 2AR6 NAG MAN MAN MAN NAG 2.77778
196 1Q8O MAN MMA 2.77778
197 4DXD GDP 2.77778
198 2PXX SAH 2.7907
199 2XVE FAD 2.80172
200 1WG8 SAM 2.80702
201 3G89 SAM 2.81124
202 2VDV SAM 2.84553
203 2G5C NAD 2.84698
204 5KVS NAP 2.85714
205 1QAN SAH 2.86885
206 3ZNN FAD 2.88184
207 3ZNN 4WL 2.88184
208 5E9W SAH 2.88462
209 3O9Z NAD 2.88462
210 3O9Z AKG 2.88462
211 1V2F HCI 2.88714
212 1EQ2 NAP 2.90323
213 4M37 SAH 2.91545
214 4M38 SAH 2.91545
215 3MAG SAH 2.9316
216 1V59 FAD 2.94118
217 1P77 ATR 2.94118
218 3LAD FAD 2.94118
219 2QA1 FAD 2.94118
220 3ABI NAD 2.94118
221 4DSG UDP 2.94118
222 4DSG FAD 2.94118
223 1CDO NAD 2.94118
224 3TLJ SAH 2.94118
225 1V59 NAD 2.94118
226 5X62 SAH 2.95567
227 2EG5 SAH 2.95699
228 4YUW 4JU 2.96053
229 4YUW S4M 2.96053
230 5EOW FAD 2.96296
231 1FWV SGA MAG FUC 2.98507
232 2DBZ NAP 2.99401
233 2J5V RGP 2.99728
234 5DN9 NAD 3.02198
235 3S5W NAP 3.02376
236 3S5W FAD 3.02376
237 1I36 NAP 3.0303
238 3MCT SAH 3.0303
239 2ZIF SAM 3.0303
240 1ZBQ NAD 3.0581
241 6B92 SAH 3.06122
242 4BJZ FAD 3.06604
243 4BJZ P3A 3.06604
244 5GZ6 NDP 3.06748
245 5GZ6 7C3 3.06748
246 1Q0S SAH 3.0888
247 4OBW SAM 3.11284
248 1UP7 NAD 3.11751
249 5O9F 9ON 3.125
250 5O9F NAD 3.125
251 1EZ4 NAD 3.14465
252 1XTP SAI 3.14961
253 5KOX RFP 3.15126
254 5KOX FAD 3.15126
255 2O4C NAD 3.15789
256 5TC4 NAD 3.16456
257 1E1M FAD 3.16742
258 1E1M NAP 3.16742
259 5XLS URA 3.16742
260 2JHP SAH 3.16742
261 3B1F NAD 3.16742
262 3PT9 SAH 3.16742
263 4OB6 S2T 3.16742
264 4XQC 13D 3.16742
265 4XQC NAD 3.16742
266 2VL8 CTS 3.16742
267 2VL8 UDP 3.16742
268 2EJU SAH 3.1746
269 5OC1 FAD 3.18584
270 5TUK FAD 3.18627
271 3UU7 2OH 3.18725
272 1RM0 D6P 3.18949
273 1RM0 NAI 3.18949
274 4JJF FE9 3.19767
275 4JJF N2I 3.19767
276 3LL5 IP8 3.21285
277 1SC6 NAD 3.21782
278 1GV0 NAD 3.22581
279 2RH4 EMO 3.2491
280 1C3V NDP 3.26531
281 3C8F MT2 3.26531
282 2YX1 SFG 3.27381
283 5BJX NAD 3.27869
284 5BJX UDP 3.27869
285 4CP8 MLI 3.28542
286 2C7G ODP 3.28947
287 2C7G FAD 3.28947
288 5CAE COA 3.29114
289 3BAZ NAP 3.3033
290 5NUF NAD 3.31325
291 2DT5 NAD 3.31754
292 6GAS FAD 3.32326
293 1AX2 NDG GAL 3.34728
294 5D4V SAH 3.35821
295 3T7S SAM 3.35821
296 2X6T NAP 3.36134
297 4ONQ SFG 3.36134
298 1FNZ A2G 3.37553
299 2ZXI FAD 3.39367
300 5UAV NDP 3.39367
301 3NB0 G6P 3.39367
302 5UAV TFB 3.39367
303 4XDY NAI 3.39367
304 5E4R NAP 3.39367
305 4ZNO SUC 3.39367
306 5JJR SAH 3.39367
307 1X9I G6Q 3.39367
308 5CX6 CDP 3.39367
309 1C3M MAN MAN 3.40136
310 4D3S BOG 3.41297
311 5TOW NAI 3.4398
312 5TOW ADN 3.4398
313 3H2B SAH 3.44828
314 1GZ6 NAI 3.44828
315 2XOC ADE 3.44828
316 1NE7 AGP 3.46021
317 1NPD NAD 3.47222
318 2JHF NAD 3.47594
319 1D1T NAD 3.48525
320 2PWY SAH 3.48837
321 5X20 NAD 3.52564
322 5N5D SAM 3.53982
323 5A04 NDP 3.53982
324 5A04 BGC 3.53982
325 2NXE SAM 3.54331
326 2GZ3 NAP 3.55191
327 1J5P NAD 3.55731
328 5FUB SAH 3.56083
329 3L4S NAD 3.57143
330 3L4S 3PG 3.57143
331 3SSO SAH 3.57995
332 1WQ1 AF3 3.59281
333 1J49 NAD 3.6036
334 5A96 GTP 3.61446
335 5MIT FAD 3.61991
336 5MIT NAP 3.61991
337 3SQP FAD 3.61991
338 1D4D FAD 3.61991
339 4EIP FAD 3.61991
340 4EIP K2C 3.61991
341 6F3N ADN 3.61991
342 6F3N NAD 3.61991
343 4OE4 NAD 3.61991
344 6BQ6 TER 3.61991
345 4NS3 NAD 3.61991
346 1OBB NAD 3.61991
347 3HAD NAD 3.61991
348 1D2E GDP 3.61991
349 5OYH T99 3.62694
350 1W6U NAP 3.64238
351 1L3I SAH 3.64583
352 3WV8 ATP 3.66972
353 6F3M NAD 3.69565
354 1LVL FAD 3.71179
355 1LVL NAD 3.71179
356 2VHW NAI 3.71353
357 3BOS CDP 3.71901
358 1OMO NAD 3.72671
359 3VGL BGC 3.73832
360 4YCA NDP 3.7415
361 2FZW NAD 3.75335
362 1LDN NAD 3.79747
363 2CDC XYP 3.82514
364 2CDC XYS 3.82514
365 2CDC NAP 3.82514
366 2VAR KDF 3.83387
367 3GDN HBX 3.84615
368 3GDN FAD 3.84615
369 5HSA FAS 3.84615
370 5BRT FAD 3.84615
371 1KNR FAD 3.84615
372 5BRT CH9 3.84615
373 1DLJ NAI 3.84615
374 2BQP GLC 3.84615
375 1G60 SAM 3.84615
376 1DLJ UGA 3.84615
377 5ZI9 FLC 3.84615
378 1RM4 NDP 3.85757
379 5YF1 SFG 3.8674
380 3L9W AMP 3.87409
381 3L9W GSH 3.87409
382 4NTC FAD 3.8806
383 1KK1 GNP 3.90244
384 5BVA FAD 3.91198
385 3LZW FAD 3.91566
386 3LZW NAP 3.91566
387 3WY9 GDP 3.91705
388 3MB5 SAM 3.92157
389 1I9G SAM 3.92857
390 3FPZ AHZ 3.98773
391 3B1Q NOS 3.98773
392 5MB4 NAG 3.99003
393 4UP4 NDG 3.99003
394 4UP4 NAG 3.99003
395 1JNR FAD 4
396 2RHO GDP 4
397 1R37 NAD 4.03458
398 1Y8Q ATP 4.04624
399 1NX0 ALA LYS ALA ILE ALA 4.04624
400 1F3L SAH 4.04984
401 1NYT NAP 4.05904
402 4TM3 FAD 4.06321
403 6F97 FAD 4.0724
404 4OPC PGT 4.0724
405 4OPC FDA 4.0724
406 5YB7 FAD 4.0724
407 5YB7 ORN 4.0724
408 3G5S FAD 4.0724
409 4XZ3 COA 4.0724
410 1VJT NAD 4.0724
411 1LTH NAD 4.07523
412 1GR0 NAD 4.08719
413 1LLU NAD 4.09357
414 1DL5 SAH 4.10095
415 2WD7 NAP 4.10448
416 1O9P MLA 4.10628
417 1ZH8 NAP 4.11765
418 4LJ9 ACP 4.12979
419 1C0I FAD 4.13223
420 1C0I BE2 4.13223
421 4LRJ ANP 4.14201
422 1SAY PYR 4.15512
423 2HMT NAI 4.16667
424 3CIF NAD 4.17827
425 3CIF G3H 4.17827
426 2ZFU SAH 4.18605
427 1SQF SAM 4.1958
428 3NYC FAD 4.19948
429 3NYC IAR 4.19948
430 5YEC ATP 4.20168
431 3FG2 FAD 4.20792
432 2OQ2 A3P 4.21456
433 3VYW SAM 4.22078
434 1RP0 AHZ 4.22535
435 5YRF GLC GLC 4.22535
436 5YRI GLC GLC 4.22535
437 2GCG NDP 4.24242
438 3ZLB ANP 4.27136
439 3QJ4 FAD 4.29864
440 4YKG NAD 4.29864
441 4YKG FAD 4.29864
442 4HA6 FAD 4.29864
443 4C3Y FAD 4.29864
444 3X0D SAH 4.29864
445 4LHD GLY 4.29864
446 4C3Y ANB 4.29864
447 3OND NAD 4.29864
448 3OND ADN 4.29864
449 3IWK NAD 4.29864
450 5HS2 CTP 4.31034
451 1PHP ADP 4.31472
452 1W6F ISZ 4.31655
453 5ZJ5 NAI 4.32099
454 4XDZ NDP 4.37318
455 6F9Q NAD 4.41176
456 3ITJ CIT 4.43787
457 3ITJ FAD 4.43787
458 5NM7 GLY 4.51128
459 1MO9 KPC 4.52489
460 1MO9 FAD 4.52489
461 1VDC FAD 4.52489
462 5WGR FAD 4.52489
463 4XFR CIT 4.52489
464 2IXB NAD 4.52489
465 5THY SAH 4.52489
466 2GJP MAL 4.52489
467 2IXB A2G 4.52489
468 5A1S FLC 4.52489
469 5A9A UTP 4.52675
470 1UXG FUM 4.53074
471 1UXG NAD 4.53074
472 3H5N ATP 4.53258
473 1DIG NAP 4.57516
474 1QPG MAP 4.57831
475 1ZEM NAD 4.58015
476 2CUN 3PG 4.63415
477 5JCM FAD 4.65632
478 5JCM NAD 4.65632
479 5JCM ISD 4.65632
480 2YVF FAD 4.65686
481 2YVF NAD 4.65686
482 2UVO NAG 4.67836
483 2FK8 SAM 4.71698
484 5O42 NAD 4.74453
485 5O42 BGC 4.74453
486 5O42 9JW 4.74453
487 1PJS NAD 4.75113
488 4MOP 2H5 4.75113
489 4RDH AMP 4.75113
490 4RDI ATP 4.75113
491 4D79 ATP 4.75113
492 1EBF NAD 4.75113
493 5Y77 FAD 4.75113
494 5M67 NAD 4.75113
495 5M67 ADE 4.75113
496 2WHX ADP 4.75113
497 5M67 3D1 4.75113
498 4G6I RS3 4.7619
499 1H5R THM 4.77816
500 1H5S TMP 4.77816
501 1DCP HBI 4.80769
502 2WPF WPF 4.84848
503 2WPF FAD 4.84848
504 5ULP KB1 4.85075
505 2D5A COA 4.86111
506 1X87 NAD 4.90018
507 5LX9 OLB 4.92958
508 2XWL CTP 4.93274
509 4B4U NAP 4.9505
510 3K5I AIR 4.96278
511 3Q9N COA 4.96454
512 3AYI FAD 4.97738
513 3AYI HCI 4.97738
514 2GVC FAD 4.97738
515 3KLJ FAD 4.97738
516 1I8T FAD 4.97738
517 1VQW FAD 4.97738
518 2GV8 FAD 4.97738
519 2GV8 NDP 4.97738
520 1VKO NAD 4.97738
521 1LJ8 NAD 4.97738
522 4CQM NAP 4.97738
523 4WBD CIT 4.97738
524 1M2W NAD 4.97738
525 2D2I NAP 5
526 2HNK SAH 5.02092
527 3AD8 NAD 5.05051
528 3AD8 PYC 5.05051
529 3AD8 FAD 5.05051
530 1PL6 NAD 5.05618
531 1PL6 572 5.05618
532 4J36 1HR 5.06024
533 4J36 FAD 5.06024
534 5GVR LMR 5.12821
535 3SJ7 NDP 5.15873
536 4XDA RIB 5.17799
537 5THZ SAH 5.18518
538 1PS9 FAD 5.20362
539 1QO8 FAD 5.20362
540 2E5V FAD 5.20362
541 5EZ7 FAD 5.20362
542 1PS9 NAP 5.20362
543 1Q3Q ANP 5.20362
544 4URF NAD 5.24194
545 2YYY NAP 5.24781
546 4USQ FAD 5.26316
547 5EES NAP 5.26316
548 1MUU NAD 5.27523
549 1MV8 NAD 5.27523
550 4FZV SAM 5.29248
551 3DAG FEG 5.30726
552 3P2E SAH 5.33333
553 4CNK FAD 5.37084
554 3MMH SME 5.38922
555 5MZI FAD 5.42299
556 5MZI FYK 5.42299
557 1HYH NAD 5.42986
558 4EA7 JB2 5.45455
559 4EA7 COA 5.45455
560 2XYQ SAH 5.51724
561 5T9E NAP 5.53506
562 1GET NAP 5.55556
563 1GET FAD 5.55556
564 3JQA NAP 5.55556
565 3JQ7 NAP 5.55556
566 4CM4 NAP 5.55556
567 3JQ9 NAP 5.55556
568 3BMO NAP 5.55556
569 3BMQ NAP 5.55556
570 3JQF NAP 5.55556
571 4CM8 NAP 5.55556
572 4CMI NAP 5.55556
573 3JQG NAP 5.55556
574 3JQ8 NAP 5.55556
575 4CLR NAP 5.55556
576 3JQG AX6 5.55556
577 3BMN NAP 5.55556
578 4CM9 NAP 5.55556
579 4CME NAP 5.55556
580 3JQB NAP 5.55556
581 4CLO NAP 5.55556
582 1L1E SAH 5.57491
583 4G5G GDP 5.58376
584 3U6K GDP 5.58376
585 3MEH THP 5.59441
586 3CBG SAH 5.60345
587 1U3U BNF 5.61497
588 1U3U NAD 5.61497
589 1KJ8 GAR 5.6266
590 1P0F NAP 5.63003
591 3AB1 FAD 5.65611
592 3GF4 FAD 5.65611
593 3GF4 UPG 5.65611
594 1GAD NAD 5.65611
595 1QMG APX 5.65611
596 2VYN NAD 5.65611
597 1TDF FAD 5.6962
598 1TDF NAP 5.6962
599 1X7D NAD 5.71429
600 4TSK NDP 5.71429
601 4GAH 0ET 5.74163
602 4EUE NAI 5.74163
603 2Y65 ADP 5.75342
604 4YSX FAD 5.76923
605 2AHR NAP 5.79151
606 5LD5 NAD 5.86592
607 5BUK FAD 5.88235
608 2A92 NAI 5.88235
609 4RPL FAD 5.88235
610 4RPL 3UC 5.88235
611 1GTE FAD 5.88235
612 1OFU GDP 5.88235
613 2AQJ FAD 5.88235
614 1O5O U5P 5.88235
615 2AQJ TRP 5.88235
616 3B20 NAD 5.8997
617 3B1J NAD 5.8997
618 1YS4 NAP 5.9322
619 5AHO TLA 5.95238
620 2VVG ADP 6
621 4KOA NDP 6.00601
622 9LDT NAD 6.0241
623 9LDB NAD 6.0241
624 4UP5 94W 6.06061
625 1H82 FAD 6.1086
626 1H82 GZZ 6.1086
627 3IHG FAD 6.1086
628 6AM8 TRP 6.1086
629 1T26 NAI 6.1086
630 1T26 GBD 6.1086
631 5G6U TRP 6.13027
632 1JAY NAP 6.13208
633 5EVY FAD 6.16438
634 1DJN ADP 6.17284
635 1E6E FAD 6.25
636 1O94 ADP 6.25
637 5L95 AMP 6.25
638 1Z82 NDP 6.26866
639 4BVA NDP 6.26866
640 3KB6 NAD 6.28743
641 3OZ2 FAD 6.29723
642 4REP FAD 6.33484
643 4EMI FAD 6.33484
644 1Q1R FAD 6.33484
645 4JDR FAD 6.33484
646 3NTA FAD 6.33484
647 4EMI NAD 6.33484
648 6AA8 NAD 6.33484
649 5IDB BMA 6.33803
650 5IDB MAN 6.33803
651 3WGT FAD 6.34006
652 3WGT QSC 6.34006
653 5T9C G3P 6.34328
654 1G0N PHH 6.36042
655 1G0N NDP 6.36042
656 5Z20 NAI 6.37681
657 3LCC SAH 6.38298
658 2YVJ FAD 6.42202
659 2YVJ NAI 6.42202
660 3O7W SAM 6.46258
661 4USI AKG 6.49351
662 1ONI BEZ 6.52174
663 1KOL NAD 6.53266
664 1LK7 DER 6.55022
665 2NUO BGC 6.55738
666 2GUC MAN 6.55738
667 2GUD MAN 6.55738
668 2HYQ MAN MAN 6.55738
669 2HYR BGC GLC 6.55738
670 2NU5 NAG 6.55738
671 5TS5 FAD 6.56109
672 3NT6 FAD 6.56109
673 3NTD FAD 6.56109
674 2R4J 13P 6.56109
675 2R4J FAD 6.56109
676 2CVZ NDP 6.57439
677 6CEP NAD 6.58683
678 6CEP OXM 6.58683
679 1T5C ADP 6.59026
680 1OC2 TDX 6.6092
681 1OC2 NAD 6.6092
682 5OVK NDP 6.64062
683 4YNU LGC 6.65499
684 4YNU FAD 6.65499
685 5N6C NAD 6.66667
686 1JI0 ATP 6.66667
687 4NBT NAD 6.66667
688 1ELI PYC 6.6838
689 5EB4 FAD 6.78733
690 2GMH FAD 6.78733
691 5JWC FAD 6.78733
692 4AP3 NAP 6.78733
693 4AP3 FAD 6.78733
694 3F8D FAD 6.81115
695 6BII NAP 6.90691
696 1FK8 NAD 7.00389
697 2Q0L FAD 7.01357
698 2Q0L NAP 7.01357
699 3GRU AMP 7.01357
700 5U8U FAD 7.01357
701 1P31 EPU 7.01357
702 1WPQ NAD 7.01357
703 5AYV NAP 7.01357
704 5AYV KPL 7.01357
705 3WLE NAD 7.03812
706 1R18 SAH 7.04846
707 5E1M SAH 7.05394
708 4GKV NAD 7.14286
709 2V51 ATP 7.1618
710 4Z94 ATP 7.1618
711 1SQK ADP 7.1618
712 2F1K NAP 7.16846
713 4B1V ATP 7.18085
714 5KVA SAM 7.19424
715 2PAV ATP 7.2
716 2A3Z ATP 7.2
717 2DFV NAD 7.20461
718 1EJ0 SAM 7.22222
719 1V6A TRE 7.22892
720 5ZZA ATP 7.23861
721 4ZCC FAD 7.23982
722 4ZCC NAI 7.23982
723 1REO FAD 7.23982
724 2IID FAD 7.23982
725 2IID PHE 7.23982
726 3QH2 3NM 7.23982
727 1LDM NAD 7.29483
728 1UI0 URA 7.31707
729 1DRV A3D 7.32601
730 5TUF TDC 7.33496
731 5TUF FAD 7.33496
732 1NVM NAD 7.37179
733 2Q7V FAD 7.38462
734 2BTO GTP 7.40741
735 2QMC GTB 7.42706
736 1IXE CIT 7.42706
737 2JB2 FAD 7.46606
738 2JB2 PHE 7.46606
739 1R55 097 7.47664
740 3MN9 ATP 7.48663
741 3MN5 ATP 7.52089
742 1J0X NAD 7.53012
743 4C5N ACP 7.6087
744 4PU6 ASP 7.63359
745 4JNA FAD 7.64706
746 6AIN FAD 7.6555
747 6DUB SAH 7.65766
748 5J5Z FAD 7.66129
749 3A4T SFG 7.66423
750 1RJW ETF 7.66962
751 5X68 FAD 7.67263
752 3RNM FAD 7.67677
753 3HDY FAD 7.69231
754 3HDY FDA 7.69231
755 3HDY GDU 7.69231
756 1IYB 5GP 7.69231
757 1F9A ATP 7.7381
758 3AFN NAP 7.75194
759 4URG C2E 7.78443
760 5FII PHE 7.84314
761 2BKX F6R 7.85124
762 2O07 MTA 7.89474
763 2O07 SPD 7.89474
764 1XK9 P34 7.90698
765 1Q9I FAD 7.91855
766 1Q9I TEO 7.91855
767 5KMS NAD 7.91855
768 5KMS FAD 7.91855
769 1FUR MLT 7.91855
770 4UP3 FAD 7.96178
771 4UP3 NDP 7.96178
772 4EFH ADP 8
773 1LUA NAP 8.01394
774 2F5Z FAD 8.01688
775 5DYO FLU 8.01887
776 1U1W 3HA 8.05369
777 4DPL NAP 8.07799
778 4XW2 SIM 8.08081
779 1JQ3 AAT 8.10811
780 3FPF TNA 8.1448
781 3FPF MTA 8.1448
782 4QTU SAM 8.14815
783 3OA2 NAD 8.1761
784 3H8V ATP 8.21918
785 4PL8 ATP 8.21918
786 4JBL MET 8.25959
787 5NA1 FAD 8.33333
788 2VSS ACO 8.33333
789 4YMH SAH 8.33333
790 5ERG SAM 8.35509
791 2Y6Q FAD 8.37104
792 2Y6Q I7T 8.37104
793 4RYV ZEA 8.3871
794 4EMJ FAD 8.41121
795 4MO2 FAD 8.42391
796 4MO2 FDA 8.42391
797 1E3I CXF 8.51064
798 5UI2 SUC 8.51735
799 4MCC 21X 8.53659
800 1SWG BTN 8.59375
801 1BW9 NAD 8.59729
802 1BXG NAD 8.59729
803 1C1X NAD 8.59729
804 1YKJ PHB 8.62944
805 1YKJ FAD 8.62944
806 2FF3 ATP 8.66667
807 2FF6 ATP 8.66667
808 1VBO MAN 8.72483
809 5FJN FAD 8.77193
810 5FJN BE2 8.77193
811 2BOS GLA GAL GLC NBU 8.82353
812 2BOS GLA GAL GLC 8.82353
813 5ZZB ATP 8.82353
814 3IWD M2T 8.82353
815 3ULK NDP 8.9613
816 1WP4 NDP 8.99654
817 3FZG SAM 9
818 3LKZ SFG 9.03427
819 4CJX NAP 9.09091
820 5HWK BEZ 9.16667
821 6GAR FAD 9.16905
822 5EIN NAP 9.25926
823 5WP5 SAH 9.27602
824 1H2B NAJ 9.27602
825 5ODQ FAD 9.28571
826 5ODQ 9SB 9.28571
827 2YN4 39J 9.32203
828 1F8G NAD 9.375
829 2HK9 ATR 9.45455
830 2HK9 NAP 9.45455
831 3NKS FAD 9.50226
832 4PC3 GDP 9.57447
833 3G2O SAM 9.699
834 3K7M FAD 9.72851
835 3QV1 NAD 9.7561
836 1IM8 SAI 9.83607
837 5O4J 9KH 9.85401
838 5O4J PJL 9.85401
839 5O4J SAH 9.85401
840 2OOR NAD 9.89583
841 1NM5 NAD 9.89583
842 1L7E NAI 9.89583
843 5N2I NAP 9.91379
844 3UCL CYH 9.95475
845 3UCL NAP 9.95475
846 3UCL FAD 9.95475
847 3ORF NAD 9.95475
848 2Q1S NAI 10.0796
849 2B4R AES 10.1449
850 2B4R NAD 10.1449
851 3H9E NAD 10.4046
852 1OFS SUC 10.4167
853 1I7M CG 10.4478
854 1W5F G2P 10.4816
855 1M0S CIT 10.5023
856 4RSL FAD 10.6335
857 2PV7 NAD 10.7383
858 2PT9 S4M 10.9034
859 5CHR 4NC 10.9489
860 4POO SAM 11
861 5LWY OLB 11.215
862 5E8J SAH 11.3636
863 5CK5 GDP 11.3924
864 5ZW3 SAH 11.5556
865 1P1C SAH 11.5578
866 1WDK NAD 11.7949
867 4CBX ATP 11.811
868 4JLS 3ZE 11.8421
869 1JG3 ADN 11.9149
870 3KP6 SAL 11.9205
871 1D4O NAP 11.9565
872 5ZBC FAD 11.991
873 3U9Z ADP 12.069
874 2I7C AAT 12.3675
875 4IV9 FAD 12.6697
876 1YJQ NAP 12.8713
877 5YEE ATP 13.2353
878 1SZ2 BGC 13.253
879 5G3U FDA 13.3484
880 5G3U ITW 13.3484
881 4W6Z 8ID 13.5447
882 2XVM SAH 13.5678
883 2NPX FAD 13.5747
884 2NPX NAD 13.5747
885 1NVT NAP 13.5889
886 5YPU ATP 13.6364
887 4II2 ATP 14.1104
888 2IVD FAD 14.2259
889 2NU8 COA 14.2361
890 5MBX SP5 14.2534
891 5MBX FAD 14.2534
892 3QFA FAD 14.6552
893 2Q1W NAD 14.7147
894 4D3F NAP 14.8387
895 5XFI NAG NAG BMA MAN MAN NAG GAL NAG 15.0327
896 5JE8 NAD 15.2318
897 3DXY SAM 16.055
898 3LTW HLZ 16.4286
899 5ZZ6 NAD 16.8269
900 5ZZ6 ADP 16.8269
901 3OFK SAH 17.5926
902 2VVM FAD 18.0995
903 2VVL FAD 18.0995
904 1FL2 FAD 19.3548
905 4USR FAD 19.6676
906 5JCA FAD 19.7183
907 5JCA NDP 19.7183
908 1LSS NAD 20
909 1O6Z NAD 20.462
910 6F5Z SAH 21.3115
911 3Q87 SAM 21.6
912 1O8B ABF 21.9178
913 3GDH SAH 22.4066
914 3JWH SAH 23.0415
915 2YG3 FAD 23.9819
916 1LOF MAN BMA NAG NAG MAN NAG GAL GAL 24.3094
917 1LOB MMA 24.3094
918 1YY5 FAD 25.7919
919 1RSG FAD 26.2443
920 3EGI ADP 27.1845
921 3X0V FAD 27.3756
Pocket No.: 2; Query (leader) PDB : 6F7L; Ligand: CWH; Similar sites found with APoc: 10
This union binding pocket(no: 2) in the query (biounit: 6f7l.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 3GQT UFO 2.00501
2 3B9Z CO2 3.60825
3 6BR9 PGV 3.62117
4 3BM1 FMN 3.82514
5 4YMX ARG 3.84615
6 3HYW DCQ 3.84615
7 3KO0 TFP 3.9604
8 3A76 SPD 6.25
9 5Z84 CHD 10.7143
10 1RV1 IMZ 27.0588
Pocket No.: 3; Query (leader) PDB : 6F7L; Ligand: FAD; Similar sites found with APoc: 121
This union binding pocket(no: 3) in the query (biounit: 6f7l.bio1) has 36 residues
No: Leader PDB Ligand Sequence Similarity
1 5TCI 79V 1.44928
2 3DMH GMP 1.5748
3 6EL3 NAP 1.5748
4 6APL C5P 1.58371
5 5TPC GAL SIA NGA GAL SIA 1.64706
6 4KRG SAH 1.80995
7 6ECU SAH 1.89873
8 6ARJ BW4 2.00573
9 6ARJ SAH 2.00573
10 3S1S SAH 2.0362
11 1Y7I SAL 2.23881
12 4KIB SAH 2.2409
13 1BXK NAD 2.25352
14 2Q3M MLA 2.26244
15 6GKV SAH 2.2792
16 2QES ADE 2.29885
17 3TKA SAM 2.30548
18 4JGT PYR 2.34114
19 5KJW 53C 2.34192
20 6C8R SAH 2.37467
21 2G37 FAD 2.44648
22 1NV8 MEQ 2.46479
23 1NV8 SAM 2.46479
24 4QAR ADE 2.48756
25 5FWA J7C 2.48869
26 2ZWA SAH 2.48869
27 3GWZ SAH 2.48869
28 1I1N SAH 2.65487
29 4GQB 0XU 2.71493
30 5T67 JHZ 2.71493
31 2PHW MAN MAN MAN BMA MAN MAN MAN 2.77778
32 2GMP NAG MAN 2.77778
33 2GNB MAN 2.77778
34 5W7K SAH 2.88462
35 1G55 SAH 2.91545
36 4AZW SAM 2.94118
37 4HE2 AMP 2.95858
38 4WOH 4NP 3.01205
39 5XH2 NPO 3.05344
40 5XNC MTA 3.16742
41 3GU3 SAH 3.16901
42 5KXE 6Y2 3.29218
43 3BXO SAM 3.34728
44 3NDJ SAH 3.36538
45 3NDJ JHZ 3.36538
46 4E3Q PMP 3.39367
47 2BZG SAH 3.44828
48 1KPG SAH 3.48432
49 1KPH SAH 3.48432
50 1N8V BDD 3.57143
51 6FOG OXL 3.57143
52 4YMZ 13P 3.58566
53 3EVG SAH 3.63636
54 3C6K MTA 3.67454
55 3C6K SPD 3.67454
56 2WCI GSH 3.7037
57 2OUA AES 3.7234
58 2KIN ADP 3.78151
59 2VAR KDG 3.83387
60 3HYW DCQ 3.84615
61 5OBU ANP 3.84615
62 6FDF SAH 3.89222
63 4UP4 GAL NAG 3.99003
64 1WY7 SAH 4.0724
65 3U31 NAD 4.13793
66 5YRL GLC GLC 4.22535
67 5YRG BGC GLC 4.22535
68 5YRJ BGC GLC 4.22535
69 5YRM BGC GLC 4.22535
70 5BSH PRO 4.33213
71 4IWN GEK 4.36681
72 5NGZ 2BG 4.56853
73 5EI3 5O8 4.60829
74 2FKA BEF 4.65116
75 5YVT NAI 4.71976
76 4IRP UDP 4.78088
77 5BSZ SAH 4.8
78 5HJM MTA 4.82955
79 2D3S TNR 4.95868
80 3OU2 SAH 5.04587
81 5FPE 3TR 5.16796
82 6GFK SAH 5.17928
83 1Y4Z PCI 5.20362
84 2PNZ UDP 5.22088
85 5Z3I ADE 5.28302
86 3GCZ SAM 5.31915
87 3LST SAH 5.45977
88 4PTN PYR 5.53936
89 3BMO AX4 5.55556
90 3BMQ AX5 5.55556
91 1XXR MAN 5.59006
92 1FP1 SAH 5.64516
93 1QCI ADE 5.72519
94 2P41 SAH 5.90164
95 1TPY SAH 6.27178
96 3EWP APR 6.33484
97 4N49 SAM 6.54206
98 6ECT SAM 6.54206
99 2HXW FLC 6.75105
100 1KYZ SAH 6.84932
101 3BGD SAH 6.92308
102 4DCM SAM 6.93333
103 1EWK GLU 7.01357
104 2PX8 SAH 7.0632
105 3I7S PYR 7.19178
106 4UZI IMD 7.23982