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Receptor
PDB id Resolution Class Description Source Keywords
6FYL 1.95 Å EC: 2.7.12.1 X-RAY STRUCTURE OF CLK2-KD(136-496)/CX-4945 AT 1.95A HOMO SAPIENS SPLICING PHOSPHOTRANSFERASE TRANSFERASE
Ref.: X-RAY STRUCTURES AND FEASIBILITY ASSESSMENT OF CLK2 INHIBITORS FOR PHELAN-MCDERMID SYNDROME. CHEMMEDCHEM V. 13 1997 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
3NG A:501;
Valid;
none;
ic50 = 7 nM
349.77 C19 H12 Cl N3 O2 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6FYL 1.95 Å EC: 2.7.12.1 X-RAY STRUCTURE OF CLK2-KD(136-496)/CX-4945 AT 1.95A HOMO SAPIENS SPLICING PHOSPHOTRANSFERASE TRANSFERASE
Ref.: X-RAY STRUCTURES AND FEASIBILITY ASSESSMENT OF CLK2 INHIBITORS FOR PHELAN-MCDERMID SYNDROME. CHEMMEDCHEM V. 13 1997 2018
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 6FYK ic50 = 10 nM EAZ C19 H24 N4 O Cc1c2cc(cc....
2 6FYL ic50 = 7 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
70% Homology Family (15)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 2WU7 ic50 = 530 nM V25 C15 H13 Cl2 N3 O2 CCOC(=O)c1....
2 2WU6 ic50 = 29.2 nM DKI C15 H13 F2 N7 O2 S2 c1cc(c(c(c....
3 6FYR - EAQ C20 H21 N6 O CC(C)(C)c1....
4 6FT7 - E6Q C16 H10 N2 O c1ccc(cc1)....
5 6FYP ic50 = 143 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
6 6FYV ic50 = 11 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
7 6FYK ic50 = 10 nM EAZ C19 H24 N4 O Cc1c2cc(cc....
8 6FYL ic50 = 7 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
9 2VAG ic50 = 19.7 nM V25 C15 H13 Cl2 N3 O2 CCOC(=O)c1....
10 5X8I ic50 = 2 nM SQZ C24 H16 F N5 O C[C@@H](c1....
11 6FT9 - E6W C16 H9 Br N2 O c1ccc(cc1)....
12 1Z57 - DBQ C11 H11 N5 O2 c1c[nH]c2c....
13 6FYO - EAQ C20 H21 N6 O CC(C)(C)c1....
14 6FT8 - E6T C16 H10 N2 O2 c1cc(cc(c1....
15 5J1W ic50 = 0.19 uM 6FB C11 H8 N4 c1cncc2c1c....
50% Homology Family (24)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5A4T ic50 = 1.3 uM AJG C10 H7 N3 O S CC(=O)N=C1....
2 5A4Q ic50 = 2.9 uM Y3L C9 H7 Cl N2 O S CC(=O)Nc1n....
3 6EIQ Ki = 383 nM B6Z C22 H25 N5 O2 S CN1CCN(CC1....
4 6EIF Ki = 104 nM B5T C18 H14 N4 O2 S c1cc(cnc1)....
5 6A1F ic50 = 0.33 uM 9OF C15 H17 N3 O CC1(Cc2cc(....
6 5A3X ic50 = 0.8 uM QIV C9 H8 N2 O2 S CC(=O)Nc1n....
7 4YLK ic50 = 0.18 uM 4E2 C16 H8 Cl I N2 O2 c1cc2c3c(c....
8 6A1G ic50 = 0.054 uM 9OL C21 H26 N4 CC1(Cc2cc(....
9 6EIL - B6B C17 H15 N5 O2 COc1ccc(cc....
10 6EIS Ki = 252 nM B6N C22 H12 F4 N4 O c1cc2c(cc1....
11 4MQ1 - 2C3 C25 H22 Cl2 N6 O4 COc1ncc2c(....
12 6EIJ Ki = 1680 nM B5Z C23 H26 N6 O3 S c1cc(cc(c1....
13 4YLL ic50 = 0.12 uM 4E3 C16 H8 Br I N2 O2 c1cc2c3c(c....
14 6EIR Ki = 575 nM B6H C25 H30 N6 O3 S CCC(=O)Nc1....
15 6FYR - EAQ C20 H21 N6 O CC(C)(C)c1....
16 6FT7 - E6Q C16 H10 N2 O c1ccc(cc1)....
17 6FYP ic50 = 143 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
18 6FYV ic50 = 11 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
19 6FYL ic50 = 7 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
20 4IFC - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
21 4IIR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
22 4IJP ic50 = 0.016 uM 1EH C20 H14 Cl N3 O2 S2 c1cc(c2cc(....
23 6FT8 - E6T C16 H10 N2 O2 c1cc(cc(c1....
24 5J1W ic50 = 0.19 uM 6FB C11 H8 N4 c1cncc2c1c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 3NG; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 3NG 1 1
2 E1B 0.461538 0.769231
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6FYL; Ligand: 3NG; Similar sites found with APoc: 492
This union binding pocket(no: 1) in the query (biounit: 6fyl.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 3OBT SLB 1.10193
2 3X01 AMP 1.10193
3 2VPQ ANP 1.37741
4 1I7L ATP 1.61812
5 5MW8 ATP 1.65289
6 3KAL ADP 1.65289
7 5W75 SUC 1.65289
8 3ZJX BOG 1.7301
9 4NZN 2OU 1.81818
10 4NZN ANP 1.81818
11 1CBK ROI 1.875
12 3JQM GTP 1.91083
13 3DNT ATP 1.92837
14 2YW2 ATP 1.92837
15 3E5P PPI 1.92837
16 3TPV ADE 1.92837
17 2B56 U5P 1.92837
18 1M1B SPV 2.0339
19 4OHU 2TK 2.07612
20 4OHU NAD 2.07612
21 4XMF HSM 2.17391
22 3PN1 IVH 2.20126
23 2HGS ADP 2.20386
24 2YRX AMP 2.20386
25 1F52 ADP 2.20386
26 1G51 AMP 2.20386
27 5NM7 GLY 2.25564
28 4RDL FUC GAL NDG FUC 2.27273
29 1IOW PHY 2.28758
30 1IOW ADP 2.28758
31 4P25 FUC GAL NAG FUC 2.31788
32 3BP1 GUN 2.41379
33 1Z2P I3S 2.46914
34 1Z2P ACP 2.46914
35 4OCJ NDG 2.47934
36 4OCV ANP 2.47934
37 4U98 ACP 2.47934
38 4PZ6 GMP 2.47934
39 3V4S ATP 2.47934
40 6C1S EFV 2.47934
41 1P6O HPY 2.48447
42 2CIG 1DG 2.51572
43 1GSA ADP 2.53165
44 4NFE BEN 2.53165
45 5I35 ANP 2.75482
46 2V58 LZJ 2.75482
47 2VQD AP2 2.75482
48 5T63 ALA ALA ALA ALA 2.75482
49 3AKK ADP 2.76923
50 1IA9 ANP 2.85714
51 3W0O HY0 2.86533
52 3W0O ADP 2.86533
53 6FS8 E4Z 2.92683
54 1OBD ATP 2.94118
55 3I0O ADP 2.94985
56 3UDZ ADP 3.0303
57 2IO8 ADP 3.0303
58 5DZT AMP 3.0303
59 6FL8 TIY 3.0303
60 6FL8 ADP 3.0303
61 1OX5 1PR 3.0303
62 3TII ANP 3.0303
63 4MV1 ADP 3.0303
64 4XYM A12 3.04348
65 4XZ3 ACP 3.04348
66 3ETH ATP 3.09859
67 4CS9 AMP 3.1746
68 2XG5 EC5 3.21101
69 2XG5 EC2 3.21101
70 4GLW 0XT 3.27869
71 1PK8 ATP 3.30579
72 5MRH Q9Z 3.30579
73 6EAC ANP 3.30579
74 2QF7 AGS 3.30579
75 4OYA 1VE 3.30579
76 3FSY SCA 3.31325
77 1I06 TZL 3.33333
78 1F5F DHT 3.41463
79 1ZTH ADP 3.48837
80 1ZP9 ATP 3.48837
81 4I94 ANP 3.58127
82 2Z49 AMG 3.58127
83 4AZW ATP 3.58127
84 2Z48 A2G 3.58127
85 2Z48 NGA 3.58127
86 3BOF HCS 3.58127
87 5IM3 DTP 3.58127
88 5YJS SAL 3.58127
89 3WO0 ADP 3.85675
90 3WO0 ALA 3.85675
91 3VOT ADP 3.85675
92 1AUX AGS 3.85852
93 5ZCT ANP 3.92157
94 5GZ9 ANP 3.93443
95 1KDK DHT 3.9548
96 5AE9 OKO 4.13223
97 3WVR AMP 4.13223
98 4UWH JXM 4.13223
99 5OES ADP 4.13223
100 3ORQ ADP 4.13223
101 1M0W ANP 4.13223
102 6EZ6 C5Z 4.13223
103 1Z03 OCH 4.13223
104 3HQP OXL 4.13223
105 4LRJ ANP 4.14201
106 1TQP ATP 4.25532
107 5YK1 ANP 4.40771
108 4PU5 ANP 4.40771
109 4LY9 1YY 4.40771
110 4LY9 S6P 4.40771
111 5EXK 5AD 4.40771
112 4AVV CD 4.41176
113 2GTF P1R 4.44444
114 4GYI ADP 4.53401
115 3E3U NVC 4.56853
116 4JLS 3ZE 4.60526
117 2UYN 2KT 4.65116
118 5C03 AGS 4.67836
119 5EQY 5RA 4.6832
120 3KIF GDL 4.71698
121 3BU1 HSM 4.72973
122 2F9W PAU 4.79705
123 4B1L FRU 4.84848
124 1E4E ADP 4.95627
125 4WOV 3SM 5.04732
126 4FE2 ADP 5.09804
127 2BMB PMM 5.23416
128 1EHI ADP 5.23416
129 1KJ8 GAR 5.23416
130 1KJ8 ATP 5.23416
131 1M26 GAL A2G 5.26316
132 3VPD ANP 5.33808
133 6ES0 BW8 5.36278
134 2PUL ACP 5.50964
135 6AC9 ANP 5.50964
136 1VJ7 GPX 5.50964
137 4DFU QUE 5.59006
138 6G34 5ID 5.60224
139 4OUC 5ID 5.60224
140 2QX0 PH2 5.66038
141 3K5I ADP 5.78512
142 1Q8A HCS 5.78512
143 3K5I AIR 5.78512
144 2G30 ALA ALA PHE 5.81395
145 1PVC ILE SER GLU VAL 5.88235
146 1OIJ AKG 5.98007
147 5WL1 D3D 6.06061
148 5WL1 CUY 6.06061
149 6A5K SAM 6.06061
150 5D9G GLU ASN LEU TYR PHE GLN 6.09756
151 1Y7P RIP 6.27803
152 2PYW ADP 6.33609
153 5KJW 53C 6.33609
154 2WBV SIA 6.34921
155 4K55 H6P 6.45161
156 2VQ5 HBA 6.46766
157 3TDV GDP 6.53595
158 4CYI ATP 6.61157
159 5FCF GLY GLY GLY 6.61157
160 2GQS ADP 6.75105
161 2GQS C2R 6.75105
162 2GQR ADP 6.75105
163 1SQL GUN 6.84932
164 2IF8 ADP 6.88705
165 5VZ0 ADP 6.88705
166 3EEL 53T 7.04846
167 5KO1 6UY 7.06714
168 3VPC ADP 7.0922
169 4R78 AMP 7.11974
170 2QK4 ATP 7.16253
171 4WOE 3S5 7.16253
172 1TZD ADP 7.27273
173 5YBL AKG 7.32484
174 3RE4 TO1 7.36434
175 4E93 GUI 7.43802
176 4Q5H ANP 7.47126
177 6CGD GNP 7.54098
178 6CGD AKN 7.54098
179 6DW2 HD4 7.59494
180 2AQX ATP 7.61246
181 2B99 RDL 7.69231
182 2Q7D ANP 7.80347
183 4ZS4 ATP 7.81759
184 2W5P CL8 8.05369
185 3PAK MAN 8.10811
186 6FQZ 6PG 8.26446
187 1W2D 4IP 8.30189
188 1W2D ADP 8.30189
189 5LXT ACP 8.39161
190 3PDT ADP 8.72727
191 1T36 ADP 8.81543
192 3VPB ADP 8.92857
193 5FI4 5XV 8.97833
194 2BKK ADP 9.09091
195 3TM0 B31 9.12547
196 3TM0 ANP 9.12547
197 6GR0 F8W 9.1954
198 4X3R 686 9.36639
199 5C1P ADP 9.47712
200 5OJI ISN 9.61539
201 2GCG DGY 10
202 1NBU PH2 10.084
203 4O1P ANP 10.1928
204 4OAV ACP 10.7438
205 4ZGP ADP 11.2628
206 3O5N BR0 11.6071
207 3CBC DBS 11.6162
208 4O4F ATP 11.6935
209 4O4F IHP 11.6935
210 6E8I PTR 11.8343
211 5C4L SIS 12.1495
212 5C4L 4XR 12.1495
213 4P5Z Q7M 13.0194
214 3VHE 42Q 13.0919
215 3PP0 03Q 13.3136
216 3Q60 ATP 13.4986
217 5WNL STU 13.7427
218 4Y85 499 13.8554
219 3KMW ATP 13.9535
220 4CCN OGA 14.2857
221 2CSN CKI 14.4781
222 2QLU ADE 14.6497
223 1DZK PRZ 14.6497
224 5JFS 6K0 14.9351
225 5K2M ADP 15.0943
226 3GNI ATP 15.1515
227 6GWR FEW 15.2381
228 4WW7 AMP 15.3257
229 4YZN 4K5 15.331
230 3LQV ADE 15.3846
231 5QIN J2V 16.1392
232 3UIM ANP 16.2577
233 5CEO 50D 16.6667
234 4G17 0VN 16.6667
235 3HAV ATP 16.7224
236 4YMJ 4EJ 16.7763
237 5MJA 7O3 17.0492
238 2XVD AS6 17.2185
239 5TA6 79D 17.3554
240 5CKW ANP 17.6309
241 2Y6O 1N1 17.8694
242 3ORK AGS 18.6495
243 3FC2 IBI 18.806
244 5HES 032 18.8925
245 4G31 0WH 19.0635
246 5DRB 5FJ 19.9313
247 3RWP ABQ 20.2572
248 5LVP ATP 20.5788
249 5M06 ADP 20.6522
250 3C1X CKK 22.0386
251 6GZD LCI 22.5895
252 5USZ SKE 22.8374
253 4IX4 ADP 23.1429
254 4IDT T28 23.3146
255 4PNI KQQ 23.416
256 4L9I 8PR 23.416
257 4WNK 453 23.9669
258 5VC5 96M 24.2215
259 2PZI AXX 24.2424
260 4Y0X ADP 24.2667
261 4XH0 ADP 24.5179
262 5DMZ ADP 24.7934
263 4DC2 ADE 25
264 1Y57 MPZ 25.0689
265 3VRY B43 25.0689
266 5T8O 76Z 25.2149
267 3PVW QRX 25.3444
268 5UKL SIX 25.3444
269 2H8H H8H 25.3444
270 4FL3 ANP 25.6198
271 3V8S 0HD 25.6198
272 5EOB 5QQ 25.7053
273 4OH4 ANP 25.8258
274 5LPZ ADP 25.9036
275 5HCY 60D 25.9819
276 6C0T EE4 26.2248
277 5UIU 8CG 26.3158
278 5VCV 1N1 26.3666
279 3DAK ANP 26.5517
280 6BFN DL1 26.6082
281 1OPK P16 26.7218
282 3TXO 07U 26.9122
283 3H9R TAK 26.9697
284 1FIW PBZ 27.2727
285 4Y8D 49J 27.3529
286 5W4W 9WG 27.4924
287 4KBA 1QM 27.4924
288 4UAL 3FV 27.5482
289 4OTH DRN 27.566
290 5HVJ ANP 27.619
291 3LXN MI1 27.673
292 3KRL KRL 27.7612
293 3ZRM ZRM 27.8237
294 4FF8 14S 27.8237
295 1RE8 BD2 28
296 2QCS ANP 28
297 3IDB ANP 28
298 3FHI ANP 28
299 1JPA ANP 28.2051
300 5LI9 ACP 28.2857
301 6GQM F8H 28.3537
302 4U0I 0LI 28.5714
303 5DBX ANP 28.6585
304 3ALN ANP 28.7462
305 5NKB 8ZT 28.7582
306 3F7Z 34O 28.8571
307 1U59 STU 28.9199
308 2JDR L20 28.9474
309 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 28.9474
310 5LPB ADP 29.0541
311 4GJ3 0XP 29.1391
312 4ASE AV9 29.1785
313 2PVF ACP 29.3413
314 4CLI 5P8 29.3578
315 1IR3 ANP 29.4118
316 1O9U ADZ 29.4286
317 1K3A ACP 29.4314
318 6F3G CJN 29.4915
319 4UXL 5P8 29.5031
320 4E1Z 0MX 29.5533
321 6GIN IR2 29.5681
322 2WQN ADP 29.6774
323 4QMN DB8 29.6774
324 5Y80 IRE 29.7125
325 4Y93 746 29.7521
326 1U5R ATP 29.8851
327 3E8N ATP 29.912
328 3E8N VRA 29.912
329 5LI1 ANP 29.9435
330 3EKK GS2 29.9674
331 2GU8 796 30
332 4WB6 ATP 30
333 4WB7 ATP 30
334 5U6C 7YS 30.1587
335 3NW7 LGV 30.2932
336 4M69 ANP 30.3514
337 4K33 ACP 30.4615
338 5OKT 9XK 30.5732
339 2R5T ANP 30.5785
340 1VJY 460 30.6931
341 5DH3 5BS 30.7937
342 3LXK MI1 30.8869
343 4EWH T77 30.9091
344 2OO8 RAJ 30.9148
345 3GQI ACP 30.9816
346 3TTI KBI 31.1295
347 3PTG 932 31.1295
348 4WHZ 3NL 31.1295
349 3BU5 ATP 31.3725
350 4UX9 ANP 31.405
351 4AT3 LTI 31.4381
352 3G5D 1N1 31.4685
353 2X2M X2M 31.5287
354 3RI1 3RH 31.6294
355 4YZC STU 31.6804
356 4BTK DTQ 31.7507
357 6BXI ANP 31.8318
358 3TKI S25 31.8885
359 4IZY 1J2 31.9559
360 2HY0 306 31.9876
361 3MVH WFE 32.1637
362 4USF 6UI 32.2368
363 5WO4 B7V 32.4503
364 5JKG 6LF 32.4759
365 3GGF GVD 32.5581
366 4AG8 AXI 32.5949
367 4N70 2HX 32.622
368 5JGA 6KC 32.6984
369 2Z7R STU 32.7103
370 4XV1 904 32.8767
371 3SLS ANP 32.8947
372 1BYG STU 33.0935
373 2J7T 274 33.1126
374 5AX9 4KT 33.1169
375 5UR1 YY9 33.119
376 5DEY 59T 33.3333
377 5TO8 7FM 33.3333
378 2A19 ANP 33.4507
379 4CSV STI 33.4545
380 4BHN BH9 33.5329
381 3PLS ANP 33.557
382 2HK5 1BM 33.7037
383 4CRL C1I 33.8843
384 1XJD STU 33.913
385 3CY2 MB9 34.0764
386 6C7Y ADP 34.2657
387 4X7Q 3YR 34.2949
388 4CQE CQE 34.5324
389 4NFN 2KC 34.6278
390 3DLS ADP 34.9254
391 1ZY5 ANP 34.9835
392 4U44 3D9 35.241
393 4NW6 2NS 35.2941
394 3SRV S19 35.3791
395 2ZV2 609 35.5705
396 4EUU BX7 35.7367
397 3AQV TAK 35.8696
398 3BZ3 YAM 35.8696
399 4F4P 0SB 35.8974
400 5H2U 1N1 35.9551
401 2YAB AMP 36.0111
402 4I6H 1C8 36.039
403 6CZ3 FLJ 36.3636
404 4RFM 3P6 36.4662
405 6E2O S0L 37.2881
406 2RIO ADP 37.4656
407 5UPK ANP 37.5723
408 3SXS PP2 37.6866
409 2F2U M77 37.741
410 4A4X JUP 37.9928
411 4TWP AXI 38.0074
412 6CQF F97 38.3838
413 2V7O DRN 38.6905
414 5JZJ AN2 39.3939
415 3C0G 3AM 39.6011
416 3GC8 B45 39.6694
417 2F57 23D 39.7476
418 4WNP 3RJ 40.0697
419 2OFV 242 40.0722
420 5FBN 5WF 40.2214
421 3HZT J60 40.4959
422 4ONA UW1 40.4959
423 5AWM ANP 40.6091
424 2WEL K88 40.6728
425 3IGO ANP 40.7714
426 4H3Q ANP 41.1602
427 4F9C 0SX 41.2742
428 4QTB 38Z 41.3158
429 4KS7 X4Z 41.4384
430 5IH9 6BF 41.4925
431 4LOO SB4 41.5512
432 4BFM ANP 41.6168
433 3FHR P4O 41.6667
434 4H3P ANP 41.7127
435 2JLD AG1 41.8733
436 4C2V YJA 42.1053
437 5EKO N17 42.1488
438 5EH0 5NW 42.2481
439 5EFQ ADP 42.3631
440 1OUK 084 42.4242
441 5OMY 9YE 42.4552
442 4NM5 ADP 42.9752
443 2VZ6 FEF 43.131
444 4C2W ANP 43.3692
445 3KN5 ANP 43.3846
446 1CM8 ANP 43.5262
447 6CMJ F6J 43.6137
448 2B9F ADP 43.6261
449 3E7O 35F 43.8889
450 2B9H ADP 43.9093
451 2B9I ADP 43.9093
452 2B9J ADP 43.9093
453 2XK9 XK9 44.0994
454 2VN9 GVD 44.186
455 5EYK 5U5 44.2029
456 5BVE 4VG 44.3213
457 5XVG 8FX 44.3686
458 4NST ADP 44.7293
459 4JR7 GNP 44.9198
460 4L3L 5FI 45.0658
461 5G1X ADP 45.2632
462 5L8L ADP 45.2632
463 3GC0 AMP 45.2888
464 4FG8 ATP 45.3968
465 5LXM ADP 45.583
466 5ODT ADP 45.9364
467 2YAK OSV 45.9649
468 5YF9 NIO 46.0177
469 5HQ0 LZ9 46.0265
470 6GU6 1QK 46.0265
471 1Q8Y ADP 46.281
472 1Q8Y ADE 46.281
473 2PVN P63 46.3068
474 5A6N U7E 46.6431
475 1PHK ATP 46.6443
476 5EW9 5VC 46.8635
477 2BPM 529 46.9256
478 3M2W L8I 47.1572
479 3E5A VX6 47.7612
480 4CFU 2WC 47.8548
481 4AU8 Z3R 47.973
482 4BCQ TJF 48.1728
483 4BCM T7Z 48.1728
484 3O0G 3O0 48.2877
485 1UNH IXM 48.2877
486 6GUE FB8 48.6755
487 3PE2 E1B 48.9614
488 1V0O INR 49.3056
489 5MY8 RXZ 49.3113
490 4BCN T9N 49.3333
491 2XMY CDK 49.6644
492 5LMK 6ZK 49.8316
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