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Receptor
PDB id Resolution Class Description Source Keywords
6H3O 2.5 Å EC: 1.-.-.- ALCOHOL OXIDASE FROM PHANEROCHAETE CHRYSOSPORIUM MUTANT F101 PHANEROCHAETE CHRYSOSPORIUM ALCOHOL OXIDASE OCTAMER FAD-BINDING DOMAIN MUTANT F101S OXIDOREDUCTASE
Ref.: STRUCTURE-BASED ENGINEERING OF PHANEROCHAETE CHRYSO ALCOHOL OXIDASE FOR ENHANCED OXIDATIVE POWER TOWARD GLYCEROL. BIOCHEMISTRY V. 57 6209 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL H:702;
B:702;
Invalid;
Invalid;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
FAD D:701;
H:701;
B:701;
E:701;
A:701;
C:701;
F:701;
G:701;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6H3O 2.5 Å EC: 1.-.-.- ALCOHOL OXIDASE FROM PHANEROCHAETE CHRYSOSPORIUM MUTANT F101 PHANEROCHAETE CHRYSOSPORIUM ALCOHOL OXIDASE OCTAMER FAD-BINDING DOMAIN MUTANT F101S OXIDOREDUCTASE
Ref.: STRUCTURE-BASED ENGINEERING OF PHANEROCHAETE CHRYSO ALCOHOL OXIDASE FOR ENHANCED OXIDATIVE POWER TOWARD GLYCEROL. BIOCHEMISTRY V. 57 6209 2018
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 318 families.
1 6H3O - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 280 families.
1 6H3O - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 5HSA - FAS C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 6H3O - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6H3O; Ligand: FAD; Similar sites found with APoc: 696
This union binding pocket(no: 1) in the query (biounit: 6h3o.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 4B2D FBP 1.09489
2 4RPL FAD 1.25313
3 4RPL 3UC 1.25313
4 4HY1 19X 1.28205
5 1MUU NAD 1.37615
6 1MV8 NAD 1.37615
7 3NT6 FAD 1.39373
8 3NTA FAD 1.39373
9 3NTD FAD 1.41593
10 3OKP GDD 1.52284
11 3OKA GDD 1.5748
12 2IZ1 ATR 1.68776
13 3PT9 SAH 1.68971
14 2ZUX RAM 1.69205
15 1MO9 FAD 1.72084
16 1MO9 KPC 1.72084
17 4DMG SAM 1.78117
18 4KOA NDP 1.8018
19 1YQZ FAD 1.82648
20 5EVY FAD 1.82648
21 3OFK SAH 1.85185
22 1VJT NAD 1.86335
23 1OBB NAD 1.875
24 1LTH NAD 1.88088
25 4MOP 2H5 1.89573
26 5YB7 ORN 1.89655
27 5YB7 FAD 1.89655
28 2E5V FAD 1.90678
29 4KRG SAH 1.93133
30 1BXK NAD 1.97183
31 1Q19 SSC 1.98807
32 1DJN ADP 1.99693
33 2WPF WPF 2.0202
34 2WPF FAD 2.0202
35 4RSL FAD 2.02247
36 4IP7 FBP 2.02578
37 3O7W SAM 2.04082
38 2NVK NAP 2.04918
39 2NVK FAD 2.04918
40 4DSG FAD 2.06612
41 4DSG UDP 2.06612
42 3AYI HCI 2.08044
43 3AYI FAD 2.08044
44 3L4S NAD 2.08333
45 3L4S 3PG 2.08333
46 3OJO NAD 2.08817
47 1L1E SAH 2.09059
48 1RJD SAM 2.09581
49 3DMH SAM 2.09974
50 1DSS NAD 2.1021
51 4XFR CIT 2.10773
52 2JJQ SAH 2.11765
53 4BJZ P3A 2.12264
54 4BJZ FAD 2.12264
55 1F8F NAD 2.15633
56 2FK8 SAM 2.20126
57 5TUK FAD 2.20588
58 2YVF FAD 2.20588
59 2YVF NAD 2.20588
60 1NYT NAP 2.21402
61 5ZBC FAD 2.21729
62 5WP5 SAH 2.24033
63 5FWA J7C 2.24215
64 2QQF A1R 2.27273
65 4HXY NDP 2.28311
66 5DX1 SFG 2.29226
67 5DX0 SFG 2.29226
68 5DXA SFG 2.29226
69 5DX8 SFG 2.29226
70 5DWQ SFG 2.29226
71 3X0D SAH 2.30415
72 3QOX SAH 2.34742
73 1DL2 NAG NAG BMA 2.34834
74 3MB5 SAM 2.35294
75 5G3U FDA 2.36407
76 5G3U ITW 2.36407
77 2GNB MAN 2.38095
78 1Q8P MAN MMA 2.38095
79 2PHF MAN MAN BMA MAN 2.38095
80 2PHR MAN MAN BMA MAN 2.38095
81 2GNM MAN 2.38095
82 2PHW MAN MAN MAN BMA MAN MAN MAN 2.38095
83 2PHU MAN MAN MAN BMA MAN 2.38095
84 1Q8S MAN MMA 2.38095
85 2GMM MAN MAN 2.38095
86 4YCA NDP 2.38095
87 1Q8V MAN MAN 2.38095
88 2GND MAN 2.38095
89 2PHU MAN MAN 2.38095
90 4BVA NDP 2.38806
91 3A06 NDP 2.39362
92 2R4J 13P 2.39521
93 2R4J FAD 2.39521
94 3MN9 ATP 2.40642
95 1KNR FAD 2.40741
96 3TLJ SAH 2.41287
97 3U31 NAD 2.41379
98 4EMI FAD 2.43902
99 4TXI FAD 2.43902
100 4EMI NAD 2.43902
101 5TUF TDC 2.44499
102 5TUF FAD 2.44499
103 5NA1 FAD 2.45098
104 5TS5 FAD 2.47934
105 1F3L SAH 2.49221
106 1I9G SAM 2.5
107 5W71 PLP 2.5
108 5WXU FLC 2.50522
109 4FMS BDP 2.51889
110 2VAR KDG 2.55591
111 2VAR KDF 2.55591
112 4CNK FAD 2.55754
113 4CNK MEU 2.55754
114 5UR0 NAD 2.5788
115 3VPH OXM 2.58065
116 3VPH NAD 2.58065
117 4D04 NAP 2.58303
118 4D04 FAD 2.58303
119 3KLJ FAD 2.5974
120 4PTZ FMN 2.6178
121 3WBF NAP 2.62295
122 3NYC IAR 2.62467
123 3NYC FAD 2.62467
124 3QJ4 FAD 2.63158
125 4AF5 CIT 2.63158
126 6MDE MEV 2.64026
127 3A25 SAM 2.65781
128 4R5M NAP 2.65957
129 1CDO NAD 2.6738
130 2YX1 SFG 2.67857
131 2JEN GLC GLC XYS XYS 2.68199
132 2NPX FAD 2.68456
133 2NPX NAD 2.68456
134 6FDF SAH 2.69461
135 1V6A TRE 2.71084
136 5EOW FAD 2.71605
137 1GAD NAD 2.72727
138 5BRT FAD 2.73038
139 5BRT CH9 2.73038
140 4CUB GAL NAG 2.73224
141 2Y6Q FAD 2.76382
142 2Y6Q I7T 2.76382
143 4MIG G3F 2.77778
144 1PNO NAP 2.77778
145 3UCL NAP 2.79232
146 3UCL CYH 2.79232
147 3UCL FAD 2.79232
148 5LD5 NAD 2.7933
149 1O94 ADP 2.8125
150 3GU3 SAH 2.8169
151 1YS4 NAP 2.82486
152 1OJ4 ANP 2.82686
153 1LDN NAD 2.8481
154 1F8G NAD 2.86458
155 2F1K NAP 2.86738
156 1REO FAD 2.88066
157 4ZRN NAD 2.88462
158 2B4R AES 2.89855
159 2B4R NAD 2.89855
160 1DJL NAP 2.89855
161 2VSS V55 2.89855
162 1WY7 SAH 2.89855
163 4D3F NAP 2.90323
164 1X87 NAD 2.90381
165 1GZ4 ATP 2.90381
166 5U8U FAD 2.9106
167 3GF4 UPG 2.91859
168 1Z45 NAD 2.91859
169 5JJR SAH 2.91859
170 3GF4 FAD 2.91859
171 1V8B NAD 2.92276
172 1V59 NAD 2.92887
173 1V59 FAD 2.92887
174 5UAO FAD 2.95749
175 2O07 MTA 2.96053
176 2O07 SPD 2.96053
177 5FUB SAH 2.96736
178 1YXM ADE 2.9703
179 5J32 IPM 2.97767
180 1JG3 ADN 2.97872
181 5D4V SAH 2.98507
182 3G2O SAM 3.01003
183 2BRY FAD 3.01811
184 2PV7 NAD 3.02013
185 2VVL FAD 3.0303
186 2VVM FAD 3.0303
187 1E1M NAP 3.04348
188 1E1M FAD 3.04348
189 6F3M NAD 3.04348
190 4USR FAD 3.04709
191 4USQ FAD 3.04709
192 1VQW FAD 3.06346
193 5WGR FAD 3.0722
194 1PN0 IPH 3.0722
195 1PN0 FAD 3.0722
196 1R18 SAH 3.0837
197 4PKI ATP 3.08642
198 4EIP FAD 3.09654
199 4EIP K2C 3.09654
200 2GV8 FAD 3.13199
201 2GVC FAD 3.13199
202 2GV8 NDP 3.13199
203 3GFB NAD 3.14286
204 5KOX RFP 3.15126
205 5KOX FAD 3.15126
206 6DUB SAH 3.15315
207 2D2I NAP 3.15789
208 2O4C NAD 3.15789
209 2Q1S NAI 3.18302
210 3GCZ SAM 3.19149
211 4RQU NAD 3.2
212 1F20 NAP 3.21839
213 5XNC MTA 3.2345
214 2H6T IVA VAL VAL STA ALA STA 3.23529
215 3HWW AKG 3.23741
216 6APV 3L4 3.24074
217 3VYW SAM 3.24675
218 1Q1R FAD 3.24826
219 3GWZ SAH 3.25203
220 3GXO SAH 3.25203
221 2ZFU SAH 3.25581
222 4MO2 FAD 3.26087
223 4MO2 FDA 3.26087
224 1D4O NAP 3.26087
225 1CF2 NAP 3.2641
226 3HDY FAD 3.27456
227 3HDY GDU 3.27456
228 3HDY FDA 3.27456
229 1GY8 NAD 3.27456
230 2C7G FAD 3.28947
231 2C7G ODP 3.28947
232 2WPB ZZI 3.28947
233 4U8P UDP 3.31384
234 4U8P FDA 3.31384
235 1L7N ALF 3.31754
236 3GDH SAH 3.3195
237 1GET NAP 3.33333
238 1GET FAD 3.33333
239 2HQM FAD 3.34029
240 3SSO SAH 3.34129
241 3CIF NAD 3.34262
242 3CIF G3H 3.34262
243 2AQJ FAD 3.34572
244 2AQJ TRP 3.34572
245 5ULP KB1 3.35821
246 1PL6 NAD 3.37079
247 5GZ6 NDP 3.37423
248 5GZ6 7C3 3.37423
249 1JQ3 AAT 3.37838
250 1FL2 FAD 3.37942
251 4YKG FAD 3.37942
252 4YKG NAD 3.37942
253 1H82 GZZ 3.38983
254 1H82 FAD 3.38983
255 1MVQ MMA 3.38983
256 4NEC SAH 3.40909
257 5HJM MTA 3.40909
258 3H8V ATP 3.42466
259 5J5Z FAD 3.42742
260 6GAR FAD 3.4384
261 2RGO FAD 3.45964
262 4JZ8 CIT 3.47003
263 1NPD NAD 3.47222
264 3K5I AIR 3.47395
265 2YY8 MTA 3.48259
266 4O6M C5P 3.49462
267 4OBW SAM 3.50195
268 5KKA 6V0 3.52564
269 2YG3 FAD 3.53201
270 1I1N SAH 3.53982
271 1I8T FAD 3.54223
272 3IHG FAD 3.5514
273 4GLL NAD 3.56083
274 3MAG SAH 3.58306
275 5Y77 FAD 3.59408
276 4OH4 ANP 3.6036
277 3G89 SAM 3.61446
278 1M2K APR 3.61446
279 4UCI SAM 3.61446
280 5MPT SAH 3.62319
281 1ZK7 FAD 3.64026
282 6AA8 NAD 3.64238
283 5JE8 NAD 3.64238
284 4J1Q NDP 3.66379
285 3ULK NDP 3.66599
286 1VI2 NAD 3.66667
287 1ZBQ NAD 3.66972
288 3S5W FAD 3.67171
289 3S5W NAP 3.67171
290 3K6V CIT 3.67232
291 1T9D PYD 3.68664
292 1YKF NAP 3.69318
293 5F1V 3VN 3.7037
294 5KJW 53C 3.74707
295 2DKH 3HB 3.75587
296 2DKH FAD 3.75587
297 1GZ6 NAI 3.76176
298 4IV9 FAD 3.7702
299 6DNT NAD 3.77907
300 1GQ2 NAP 3.78378
301 1PZM 5GP 3.79147
302 4JDR FAD 3.79747
303 2RBK VN4 3.83142
304 3ABI NAD 3.83562
305 5JWC FAD 3.83877
306 4YSX FAD 3.84615
307 3LU1 NAD 3.84615
308 1WG8 SAM 3.85965
309 1Q0S SAH 3.861
310 4NTC FAD 3.8806
311 3X0V FAD 3.8817
312 3EGI ADP 3.8835
313 5AYV NAP 3.8835
314 1J71 THR ILE THR SER 3.89222
315 5MZI FYK 3.90456
316 5MZI FAD 3.90456
317 2OOR NAD 3.90625
318 1L7E NAI 3.90625
319 1NM5 NAD 3.90625
320 2OOR TXP 3.90625
321 5BVA FAD 3.91198
322 4IWN GEK 3.93013
323 1PJS NAD 3.93873
324 5KMS FAD 3.95062
325 5KMS NAD 3.95062
326 6C8R SAH 3.95778
327 5FQD LVY 3.99061
328 3LAD FAD 3.9916
329 6FP4 FAD 4.01338
330 6FP4 E1T 4.01338
331 5W5R PYR 4.06699
332 2C3H GLC GLC 4.08163
333 2YYY NAP 4.08163
334 2XVF FAD 4.09483
335 2XVE FAD 4.09483
336 3E1T FAD 4.10156
337 2GMH FAD 4.10959
338 1ELI PYC 4.11311
339 5YF1 SFG 4.14365
340 4RDH AMP 4.16667
341 4RDI ATP 4.16667
342 1WVG APR 4.17827
343 2VT3 ATP 4.18605
344 5THY SAH 4.19753
345 5THZ SAH 4.19753
346 4KIB SAH 4.20168
347 2Q1W NAD 4.2042
348 5BUK FAD 4.22222
349 1E6W NAD 4.23077
350 1TL2 NDG 4.23729
351 3LCC SAH 4.25532
352 1RSG FAD 4.26357
353 2DT5 NAD 4.2654
354 2G5C NAD 4.27046
355 1FEC FAD 4.28571
356 1X7D NAD 4.28571
357 1YY5 FAD 4.2885
358 4EUE NAI 4.30622
359 1UZ4 IFL 4.31818
360 1Y8Q ATP 4.33526
361 4D79 ATP 4.34783
362 1WDK NAD 4.35897
363 1PFK ADP 4.375
364 4ZEV M6P 4.39189
365 1C0I BE2 4.40771
366 1C0I FAD 4.40771
367 3K7M FAD 4.40835
368 5N5D SAM 4.42478
369 2VYN NAD 4.49102
370 1BXG NAD 4.49438
371 1BW9 NAD 4.49438
372 1BW9 PPY 4.49438
373 1C1X NAD 4.50704
374 1C1X HFA 4.50704
375 2EG5 SAH 4.56989
376 6BWL NAD 4.57317
377 3WV8 ATP 4.58716
378 4USF 6UI 4.60526
379 3ZNN FAD 4.61095
380 3ZNN 4WL 4.61095
381 3TKY SAH 4.61957
382 2P4Q FLC 4.62777
383 5FA5 MTA 4.63215
384 2JHP SAH 4.65839
385 5MGZ SAH 4.66102
386 4EMJ FAD 4.6729
387 5X62 SAH 4.6798
388 1E6E FAD 4.6875
389 2EFJ SAH 4.6875
390 1L3I SAH 4.6875
391 1A5Z NAD 4.70219
392 4CJX NAP 4.70219
393 3OA2 NAD 4.71698
394 3AB1 FAD 4.72222
395 2RGJ FAD 4.72637
396 4AP3 NAP 4.73588
397 4AP3 FAD 4.73588
398 1QO8 FAD 4.77032
399 3OZ2 FAD 4.78589
400 1WQ1 AF3 4.79042
401 2QA1 FAD 4.8
402 1J49 NAD 4.8048
403 4IF4 BEF 4.80769
404 1NVM NAD 4.80769
405 5W7M SAH 4.80769
406 3SQP FAD 4.81172
407 4EKQ NPO 4.81283
408 3NKS FAD 4.8218
409 1VM6 NAD 4.82456
410 1GV0 NAD 4.83871
411 1GUZ NAD 4.83871
412 5BW4 SAM 4.86891
413 2VDV SAM 4.87805
414 4MCC 21X 4.87805
415 5WP4 SAH 4.88798
416 5I39 FAD 4.90196
417 4C4A SAH 4.91551
418 4GQB 0XU 4.94186
419 6AIN FAD 5.02392
420 2PWY SAH 5.03876
421 3DXY SAM 5.04587
422 1Q9I TEO 5.06912
423 1Q9I FAD 5.06912
424 3C6K MTA 5.06912
425 3C6K SPD 5.06912
426 2P3V SRT 5.07812
427 5OVK NDP 5.07812
428 2HK9 ATR 5.09091
429 2HK9 NAP 5.09091
430 5X68 FAD 5.11509
431 4IMG NGF 5.11945
432 6GAS FAD 5.13595
433 1BZL FAD 5.14403
434 1BZL GCG 5.14403
435 5YEE ATP 5.14706
436 5LOG SAH 5.15021
437 5IGL BMF 5.16129
438 3RNM FAD 5.17241
439 3CBG SAH 5.17241
440 3WGT FAD 5.18732
441 3WGT QSC 5.18732
442 4USI AKG 5.19481
443 1D4D FAD 5.22273
444 5TWB FAD 5.23256
445 1LVL FAD 5.24017
446 1LVL NAD 5.24017
447 5DM1 SAH 5.24345
448 4B4U NAP 5.28053
449 4KRI SAH 5.31178
450 3ITJ FAD 5.32544
451 1IM8 SAI 5.32787
452 4L8V NAP 5.34125
453 4P8O 883 5.34759
454 4N49 SAM 5.37383
455 1PS9 FAD 5.37634
456 1PS9 NAP 5.37634
457 6CEP NAD 5.38922
458 1VDC FAD 5.40541
459 3H2B SAH 5.41872
460 2IID PHE 5.42169
461 2IID FAD 5.42169
462 1HDG NAD 5.42169
463 9LDB NAD 5.42169
464 2HJ9 AI2 5.42986
465 6BQ6 TER 5.43807
466 3BXO SAM 5.43933
467 1SC6 NAD 5.44554
468 6BT4 KPM 5.44554
469 1O0S NAI 5.45455
470 2Q0L FAD 5.46624
471 2Q0L NAP 5.46624
472 2ZXI FAD 5.49451
473 1RYI GOA 5.49738
474 1RYI FAD 5.49738
475 3NJ4 NAD 5.51724
476 2JB2 FAD 5.52147
477 2JB2 PHE 5.52147
478 6G3R ADP 5.52632
479 4M37 SAH 5.53936
480 4M38 SAH 5.53936
481 5JCM FAD 5.54324
482 5JCM ISD 5.54324
483 5JCM NAD 5.54324
484 3F8D FAD 5.57276
485 3FXU TSU 5.57377
486 4B52 RDF 5.59211
487 6D5X ATP 5.61225
488 1GTE FAD 5.68356
489 4UP3 FAD 5.73248
490 4UP3 NDP 5.73248
491 1X14 NAD 5.73566
492 1QAN SAH 5.7377
493 4OPC PGT 5.73951
494 4OPC FDA 5.73951
495 5KVA SAM 5.7554
496 5MIT NAP 5.8104
497 5MIT FAD 5.8104
498 5MBX SP5 5.83501
499 5MBX FAD 5.83501
500 2Q7V FAD 5.84615
501 2Q28 ADP 5.85106
502 2IVD FAD 5.85774
503 1P77 ATR 5.88235
504 3LKZ SFG 5.919
505 2DC1 NAD 5.9322
506 1XCL SAH 5.95745
507 4J36 1HR 5.99078
508 4J36 FAD 5.99078
509 5J6H NCA 6
510 2FWP ICR 6.01093
511 2FWP CIT 6.01093
512 6EL3 NAP 6.03675
513 3GGO NAI 6.05096
514 3MCT SAH 6.06061
515 5X20 NAD 6.08974
516 1EJ0 SAM 6.11111
517 3FPZ AHZ 6.13497
518 5FJN FAD 6.14439
519 5FJN BE2 6.14439
520 1HYH NAD 6.14887
521 3G4Q MCH 6.16438
522 4TQG NDP 6.19195
523 4NAE 1GP 6.22222
524 1IXI 2HP 6.23053
525 2F5Z FAD 6.25
526 2V7O DRN 6.25
527 4NV0 MG7 6.26959
528 5OFW 9TW 6.27803
529 3VSE SAH 6.28141
530 2EJU SAH 6.34921
531 4REP FAD 6.46465
532 4JNA FAD 6.47059
533 1COY FAD 6.50888
534 1COY AND 6.50888
535 2XVM SAH 6.53266
536 3G5S FAD 6.54628
537 5KOK SAH 6.54912
538 4AT0 FAD 6.66667
539 6F92 MVL 6.75883
540 4C3Y FAD 6.79245
541 4C3Y ANB 6.79245
542 1OMO NAD 6.8323
543 2AOT SAH 6.84932
544 5K4W NAI 6.85358
545 4M52 FAD 6.86695
546 4M52 M52 6.86695
547 2A8X FAD 6.89655
548 3B1F NAD 6.89655
549 1WP4 NDP 6.92042
550 3AFH GSU 6.96721
551 2RGH FAD 7.00525
552 2VZ6 FEF 7.02875
553 1P1C SAH 7.03518
554 4YMH SAH 7.08333
555 2HNK SAH 7.11297
556 5N53 8NB 7.17949
557 2P41 SAH 7.21311
558 3Q72 GNP 7.22892
559 1CER NAD 7.25076
560 5O4J 9KH 7.29927
561 5O4J SAH 7.29927
562 5O4J PJL 7.29927
563 3A27 SAM 7.35294
564 5ZZB ATP 7.35294
565 1YKJ FAD 7.36041
566 1YKJ PHB 7.36041
567 3JWH SAH 7.37327
568 4BQS ADP 7.38636
569 2A92 NAI 7.47664
570 2DFV NAD 7.4928
571 1EBF NAD 7.5419
572 5YEC ATP 7.56302
573 1GG6 APL 7.63359
574 3FG2 FAD 7.67327
575 4TM3 FAD 7.67494
576 3Q9L ATP 7.69231
577 1QHH ATP 7.78443
578 5ERG SAM 7.78689
579 3T7S SAM 7.83582
580 5ZYN FAD 7.85563
581 1EZ4 NAD 7.86164
582 4CBX ATP 7.87402
583 1I36 NAP 7.95455
584 2CDU FAD 7.9646
585 2CDU ADP 7.9646
586 5AHS SIN 7.98005
587 3O5N BR0 8.03571
588 2UYQ SAM 8.06452
589 3DUW SAH 8.07175
590 1RP0 AHZ 8.09859
591 4ZJS 4P0 8.26087
592 3QV1 NAD 8.30861
593 2Z9I GLY ALA THR VAL 8.33333
594 3H9E NAD 8.3815
595 3KIF GDL 8.49057
596 4JK3 NAD 8.49421
597 3B20 NAD 8.55457
598 1LSS NAD 8.57143
599 1FWV SGA MAG FUC 8.95522
600 4LWP SAH 8.96739
601 2XYQ SAH 9.01639
602 2PT9 S4M 9.03427
603 2PT9 2MH 9.03427
604 3I53 SAH 9.03614
605 1LSH PLD 9.21659
606 2PEL LBT 9.32203
607 5DNK SAH 9.38628
608 1XTP SAI 9.44882
609 3LST SAH 9.48276
610 3A4T SFG 9.48905
611 4X1T UDP 9.55882
612 3GRU AMP 9.83051
613 2BES RES 9.88372
614 3L9W GSH 9.92736
615 3L9W AMP 9.92736
616 3LZW NAP 9.93976
617 3LZW FAD 9.93976
618 5ODQ FAD 9.96564
619 2YVJ NAI 10.0917
620 2YVJ FAD 10.0917
621 1NVT NAP 10.1045
622 4POW OP1 10.1887
623 1KYQ NAD 10.219
624 2I7C AAT 10.2473
625 1ZEM NAD 10.3053
626 3FUU ADN 10.3321
627 1TDF FAD 10.443
628 1TDF NAP 10.443
629 3HZT J60 10.4925
630 1J0X NAD 10.5422
631 5E9W SAH 10.5769
632 5E8J SAH 10.5769
633 5EZ7 FAD 10.9694
634 3OU2 SAH 11.0092
635 1G55 SAH 11.0787
636 4CQM NAP 11.1111
637 5L95 AMP 11.25
638 1JNR FAD 11.3333
639 5BJX NAD 11.4754
640 1ORR NAD 11.5274
641 1RM4 NDP 11.5727
642 1ZQ9 SAM 11.5789
643 4ZCC FAD 11.6071
644 4ZCC NAI 11.6071
645 3H5N ATP 11.6147
646 1XT8 CYS 11.6438
647 5CKS GAL 11.6809
648 5EES NAP 11.7409
649 5TH5 MET 11.7871
650 4QTU SAM 11.8519
651 3V1Y NAD 11.8694
652 5IKB KAI 12.4514
653 1DL5 SAH 12.6183
654 1FP2 SAH 12.7841
655 6BJO DUY 12.8
656 4UXM BE7 12.8788
657 4UUU SAM 12.9032
658 5LWY OLB 13.0841
659 2HMT NAI 13.1944
660 5ZW3 SAH 13.3333
661 4Z0H NAD 13.4731
662 4J56 FAD 14.0351
663 5W7K SAH 14.1026
664 1UP7 NAD 14.3885
665 6CS9 PIO 14.6341
666 5ZZ6 ADP 15.8654
667 5ZZ6 NAD 15.8654
668 5N0J FAD 15.9544
669 3B1J NAD 16
670 5JCA FAD 16.0338
671 5JCA NDP 16.0338
672 5BWD FUM 16.6667
673 4II2 ATP 16.8675
674 3AD8 NAD 18.5644
675 3AD8 FAD 18.5644
676 3AD8 PYC 18.5644
677 3QFA FAD 19.8276
678 5ZZA ATP 19.8347
679 3BGD SAH 21.5385
680 4OGQ 7PH 23.5294
681 1NAA 6FA 23.6599
682 1NAA ABL 23.6599
683 5E1M SAH 24.4813
684 6F5Z SAH 24.5902
685 5EB4 FAD 24.6241
686 4B1X ATP 25
687 3GDN HBX 26.6795
688 3GDN FAD 26.6795
689 6F97 FAD 28.2486
690 4HA6 FAD 29.5276
691 4B1V ATP 31.25
692 3QVP FAD 42.3671
693 1GPE FAD 42.4191
694 5OC1 FAD 46.5487
695 4YNU LGC 48.3363
696 4YNU FAD 48.3363
Pocket No.: 2; Query (leader) PDB : 6H3O; Ligand: FAD; Similar sites found with APoc: 137
This union binding pocket(no: 2) in the query (biounit: 6h3o.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 2AJ4 ANP 0.912409
2 1V47 ADX 1.43266
3 5H6S HDH 1.4553
4 1TV5 N8E 1.80587
5 1KXP ATP 1.86667
6 5YPU ATP 1.90217
7 3DAG FEG 1.95531
8 2PZM NAD 2.12121
9 2PZM UDP 2.12121
10 3MN5 ATP 2.22841
11 5XGX DAS DLY 2.27848
12 3BXF 13P 2.35294
13 1UKG MMA 2.38095
14 2GND MAN MMA 2.38095
15 2PHT MAN MAN MAN BMA MAN 2.38095
16 2AUY NAG MAN MMA 2.38095
17 3A1I UNU 2.4952
18 5CK5 GDP 2.53165
19 2WT9 NIO 2.55319
20 4P83 U5P 2.74725
21 2YJP CYS 2.74914
22 1VAY AZA 2.78746
23 1NW5 SAM 2.82132
24 1NJJ GET 2.82353
25 4ZRN UPG 2.88462
26 3N8K D1X 2.90698
27 2IXE ATP 2.95203
28 2EB5 OXL 2.99625
29 2A42 ATP 3.07692
30 4WZ6 ATP 3.10345
31 4CP8 MLI 3.28542
32 2ZIF SAM 3.367
33 5TDF 7A3 3.39506
34 4PPF FLC 3.42857
35 2YY8 SAM 3.48259
36 5OJ7 AR6 3.4965
37 1XF1 CIT 3.53303
38 5A04 BGC 3.53982
39 5A04 NDP 3.53982
40 2FJK 13P 3.60656
41 1GJW GLC 3.61068
42 2GLX NDP 3.61446
43 3QX9 ATP 3.62319
44 5W8X UDP 3.66492
45 3UIM ANP 3.68098
46 1OFU GDP 3.75
47 2HFK E4H 3.76176
48 1KEW NAD 3.87812
49 2CST MAE 3.89294
50 1ZGA SAH 3.92157
51 2AWN ADP 4.19948
52 5LQ8 GB 4.25532
53 4Y30 SAH 4.2735
54 2BZG SAH 4.31034
55 2J5V PCA 4.35967
56 2ZHZ ATP 4.37158
57 1KYZ SAH 4.38356
58 1BGV GLU 4.45434
59 5F90 GLA GAL BGC 5VQ 4.48718
60 1HDR NAD 4.5082
61 1FP1 SAH 4.56989
62 4FZV SAM 4.60251
63 5DCH 1YO 4.6875
64 5A1T NAI 4.69208
65 3RFV 15L 4.86891
66 6H1U ASP 4.87805
67 2WZM NA7 4.947
68 3ACC 5GP 4.97238
69 1R6D NAD 5.04451
70 1R6D DAU 5.04451
71 3TTZ 07N 5.05051
72 3GFS FMN 5.17241
73 5NM7 GLY 5.26316
74 3LM9 ADP 5.29801
75 4PKG ATP 5.37634
76 5N6N SUC 5.41667
77 9LDT NAD 5.42169
78 4PL8 ATP 5.47945
79 3NJ4 AFX 5.51724
80 1ONI BEZ 5.7971
81 2HJ4 PNZ 5.81717
82 1P31 EPU 5.83717
83 3C3Y SAH 5.90717
84 4JLS 3ZE 5.92105
85 2W58 ADP 5.94059
86 2G50 ALA 6.03774
87 5LJI FMN 6.08108
88 1AE1 NAP 6.22711
89 5BQ5 ADP BEF 6.34921
90 3LL5 IP8 6.4257
91 2J9L ATP 6.48649
92 3GYQ SAM 6.61765
93 5IL1 SAM 6.66667
94 6BLD DXJ 6.68258
95 3D3W NAP 6.96721
96 1VHZ APR 7.07071
97 1U2Z SAH 7.3903
98 1QR0 COA 7.45614
99 5IFS ADP 7.59494
100 5ZI9 FLC 7.69231
101 5YRF GLC GLC 7.74648
102 3ZG6 APR 7.77027
103 1H5T TYD 7.84983
104 2YVE MBT 8.10811
105 2IV3 UDP 8.18713
106 5F8F SFG 8.22281
107 5BSZ SAH 8.4
108 3VY6 BGC BGC 8.51064
109 2FF6 ATP 8.66667
110 2BOS GLA GAL GLC NBU 8.82353
111 2RCN GDP 8.93855
112 2WK1 SAH 9.21986
113 3AB4 THR 10.1124
114 3KIH GDL 10.3093
115 4UBP HAE 11.1111
116 1G6H ADP 11.284
117 5BJX UDP 11.4754
118 4JWX 1N4 11.7857
119 3F4F UMP 11.976
120 1UNQ 4IP 12
121 1UJ5 5RP 13.6564
122 1HGX 5GP 14.2077
123 2J9D ADP 14.2857
124 3D36 ADP 15.2174
125 2PBD ATP 16.2791
126 4MZU COA 16.6667
127 2OFW ADX 16.8269
128 2QQC AG2 16.9811
129 1N13 AG2 17.3077
130 1QH9 LAC 19.3966
131 3SJH ATP 20.3704
132 2FF3 ATP 26.6667
133 4KXQ APR 26.6667
134 2D1K ATP 34.375
135 2PAV ATP 37.5
136 5C2N NAG 41.6667
137 5OC1 ANN 46.5487
Pocket No.: 3; Query (leader) PDB : 6H3O; Ligand: FAD; Similar sites found with APoc: 56
This union binding pocket(no: 3) in the query (biounit: 6h3o.bio1) has 41 residues
No: Leader PDB Ligand Sequence Similarity
1 1TV5 A26 1.80587
2 2V51 ATP 1.85676
3 5DNC ASN 1.87075
4 1YQT ADP 2.04461
5 1UZN NAP 2.42915
6 4A59 AMP 2.45499
7 3BY9 SIN 2.69231
8 4P6G 2FZ 3.09735
9 2V7Y ADP 3.14342
10 5EGM 5NY 3.40426
11 5C9P FUC 3.41207
12 1HXD BTN 3.42679
13 3CNL GNP 3.43511
14 4LS3 HIS 3.6036
15 4YUW S4M 3.61842
16 4YUW 4JU 3.61842
17 5AEW BNL 3.7234
18 2VMG MBG 3.82166
19 4PQG NAG 4.10959
20 2GQR ADP 4.21941
21 2NV2 GLN 4.41176
22 4MO4 ACP 4.58221
23 4YMX ARG 5
24 1O8B ABF 5.02283
25 1RZX ACE VAL LYS GLU SER LEU VAL 5.10204
26 1NJR XYL 5.28169
27 2D3S TNR 5.3719
28 1FQK ALF 5.44218
29 1R6B ADP 5.83717
30 2PX8 SAH 5.94796
31 2DT9 THR 5.98802
32 1M26 GAL A2G 6.01504
33 1N8V BDD 6.25
34 3QPB URA 6.38298
35 3HBN UDP 6.38298
36 1JPA ANP 6.73077
37 2JK0 ASP 6.76923
38 2WG9 OCA 6.92308
39 3NY4 SMX 7.16981
40 5HVJ ANP 7.30159
41 1A0J BEN 7.62332
42 1XXA ARG 7.69231
43 3B6O TMP 8.09717
44 3EVG SAH 8.36364
45 2Q97 ATP 8.52713
46 2FMD MAN MAN 8.75
47 1HSL HIS 9.66387
48 5HX1 UMP 10.8696
49 5FA8 SAM 11.1801
50 5AHW CMP 11.5646
51 1LSZ NDG NAG NAG NAG 12.9252
52 1SQF SAM 20.2797
53 3HYK A3P 22.1311
54 1QD0 RR6 25
55 3DZ6 M8E 25.3731
56 1LOB MMA 28.8462
Pocket No.: 4; Query (leader) PDB : 6H3O; Ligand: FAD; Similar sites found with APoc: 76
This union binding pocket(no: 4) in the query (biounit: 6h3o.bio1) has 41 residues
No: Leader PDB Ligand Sequence Similarity
1 6BOC EU7 None
2 5TE1 7A2 0.921659
3 3VM7 GLC 1.42276
4 1CT9 AMP 1.44665
5 1QHG ATP 1.5361
6 3IWK NAD 1.59046
7 5HTX ADP 1.59453
8 5LY3 ADP 2.08333
9 1QMG APX 2.09924
10 6EWR PMP 2.10773
11 3KC1 2T6 2.37389
12 2GMP NAG MAN 2.38095
13 2AR6 NAG MAN MAN MAN NAG 2.38095
14 4TQK NAG 2.46305
15 5XLS URA 2.52874
16 4EFH ADP 2.66667
17 1GEE NAD 2.68199
18 3ERR AMP 2.79851
19 2WW4 ADP 2.82686
20 4R8L ASP 2.85714
21 4D52 GXL 2.85714
22 4D4U FUC GAL NAG 2.85714
23 5VLQ ANP 2.88625
24 2B3B GLC 3
25 6GNF ADP 3.125
26 3S6X SIA GAL BGC 3.38462
27 2F6U CIT 3.4188
28 1T9D P22 3.68664
29 1KAE NAD 3.68664
30 3CV2 OXL 3.7594
31 3QFU ADP 3.80711
32 5FUS DAO 3.83275
33 1M2W NAD 3.85396
34 5LVP ATP 3.85852
35 2PXX SAH 4.18605
36 4BGB ADP 4.30769
37 6GYT GLY LEU GLY ALY GLY GLY ALA ALY ALA 4.34783
38 2Z49 AMG 4.39815
39 2Z48 NGA 4.39815
40 3DVA TPW 4.43925
41 4UYG 73B 4.4586
42 4ZLU ADP 4.47427
43 4LOC OXM 4.90506
44 1ZGS XMM 4.9217
45 1QCI ADE 4.96183
46 3RGG AIR 5.03145
47 1H5Q NAP 5.28302
48 3BBH SFG 5.36585
49 5TSH ANP 5.61225
50 5E5U MLI 5.68182
51 5FPE 3TR 5.68475
52 4P5E N6P 5.92105
53 1Q8Y ADE 6.43432
54 1T5B FMN 6.46766
55 1XKV ATP 6.61626
56 1DKU AP2 6.62461
57 5W10 CMP 6.66667
58 2NGR AF3 7.32984
59 1OYF MHN 7.43802
60 1VKF CIT 7.44681
61 6FLZ MMA 7.63889
62 5YRI GLC GLC 7.74648
63 1UCN ADP 7.89474
64 4TR9 38D 8.13008
65 4F8L AES 8.27586
66 4JAL SAH 8.38323
67 6AR9 3L4 8.45588
68 2BOS GLA GAL GLC 8.82353
69 4NBT NAD 9.58333
70 2VE3 REA 10.1351
71 2OQ5 BEN 10.3448
72 1WUW TSU 15.5556
73 1L6O SER LEU LYS LEU MET THR THR VAL 15.7895
74 1GXS BEZ 17.0886
75 1APZ ASP 17.284
76 3U9Z ADP 27.5862
Pocket No.: 5; Query (leader) PDB : 6H3O; Ligand: FAD; Similar sites found with APoc: 27
This union binding pocket(no: 5) in the query (biounit: 6h3o.bio1) has 40 residues
No: Leader PDB Ligand Sequence Similarity
1 2ZWS PLM 0.928793
2 3GD8 GOL 1.79372
3 6G14 G4P 2.04082
4 1USI PHE 2.31214
5 2QPU QPU 2.71605
6 2VSU V55 2.90909
7 5MRH Q9Z 2.91859
8 3KN5 ANP 3.07692
9 4HMX FMN 3.25581
10 2JKY 5GP 3.75587
11 1NML CIT 3.98773
12 4ZM4 PLP 4.25056
13 1SDW IYT 4.4586
14 6FBA D48 5.15759
15 1P9B HDA 5.20362
16 1XFF GLU 5.41667
17 1BKC INN 5.46875
18 1FTH A3P 5.7377
19 5AZC PGT 6.33333
20 4RL4 PPV 6.60377
21 2WA2 SAM 7.97101
22 3UKR CKH 8.98876
23 1SQ5 ADP 9.09091
24 5XQL C2E 9.27835
25 6FX2 FUC C4W NAG BMA MAN NAG GAL 9.30233
26 3QMN A3P 11.6279
27 5HP8 PYR 12.0968
Pocket No.: 6; Query (leader) PDB : 6H3O; Ligand: FAD; Similar sites found with APoc: 36
This union binding pocket(no: 6) in the query (biounit: 6h3o.bio1) has 41 residues
No: Leader PDB Ligand Sequence Similarity
1 2NZ2 ASP 1.45278
2 2Q89 6CS 2.33463
3 2AR6 NAG MAN 2.38095
4 1Q8Q MAN MMA 2.38095
5 4ZLA BES 2.39044
6 2BHZ MAL 2.65781
7 1OYY AGS 2.86807
8 4PZ6 GMP 2.97767
9 1VMK GUN 3.61011
10 5N6C NAD 4
11 5Z21 NAI 4.18994
12 1E3W NAD 4.21456
13 3AY6 BGC 4.46097
14 2HIM ASN 5.02793
15 4RKS MEV 5.04451
16 1W3T 3GR 5.10204
17 3LTW HLZ 5.35714
18 4KAX 4IP 5.59006
19 5JBX MLI 5.74713
20 6FOG OXL 5.80357
21 5U75 SIA GAL NDG FUC 5.95238
22 4RUS NAG 7.14286
23 1J1R ADE 7.66284
24 5YRJ BGC GLC 7.74648
25 5YRG BGC GLC 7.74648
26 2UYP PPI 7.75194
27 2X61 CH 7.75194
28 1LK7 DER 7.86026
29 5OD2 GLC 8.95197
30 4YDU ADP 9.0379
31 2A9G ARG 9.09091
32 5H4S RAM 9.15493
33 3FZG SAM 11
34 6CZY PMP 12.7072
35 4WAS COO 12.9121
36 3IP8 B85 18.9516
Pocket No.: 7; Query (leader) PDB : 6H3O; Ligand: FAD; Similar sites found with APoc: 27
This union binding pocket(no: 7) in the query (biounit: 6h3o.bio1) has 40 residues
No: Leader PDB Ligand Sequence Similarity
1 5OBU ANP 1.70132
2 1UWK NAD 1.97487
3 1UWK URO 1.97487
4 4WOE ADP 1.99693
5 5T96