Receptor
PDB id Resolution Class Description Source Keywords
6HRX 1.87 Å NON-ENZYME: TRANSCRIPT_TRANSLATE ETHR2 IN COMPLEX WITH COMPOUND 2 (BDM72201) MYCOBACTERIUM TUBERCULOSIS H37RV HELIX-TURN-HELIX TETR-FAMILY COMPLEX INHIBITOR DRUG DESITUBERCULOSIS ETHIONAMIDE DNA BINDING PROTEIN
Ref.: A FRAGMENT-BASED APPROACH TOWARDS THE DISCOVERY OF N-SUBSTITUTED TROPINONES AS INHIBITORS OF MYCOBACTE TUBERCULOSIS TRANSCRIPTIONAL REGULATOR ETHR2. EUR J MED CHEM V. 167 426 2019
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GO8 B:301;
A:301;
 Valid;
Valid;
 none;
none;
 ic50 = 0.00000001 M
209.271 C8 H11 N5 S CC(C)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6HS2 1.87 Å NON-ENZYME: TRANSCRIPT_TRANSLATE ETHR2 IN COMPLEX WITH COMPOUND 31 (BDM76150) MYCOBACTERIUM TUBERCULOSIS (STRAIN ATCH37RV) HELIX-TURN-HELIX TETR-FAMILY COMPLEX INHIBITOR DRUG DESITUBERCULOSIS ETHIONAMIDE DNA BINDING PROTEIN
Ref.: A FRAGMENT-BASED APPROACH TOWARDS THE DISCOVERY OF N-SUBSTITUTED TROPINONES AS INHIBITORS OF MYCOBACTE TUBERCULOSIS TRANSCRIPTIONAL REGULATOR ETHR2. EUR J MED CHEM V. 167 426 2019
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 308 families.
1 6HRX ic50 = 0.00000001 M GO8 C8 H11 N5 S CC(C)Sc1[n....
2 6HS0 ic50 = 0.00000001 M GNW C11 H15 Cl N2 c1cc(cc(c1....
3 6HRW ic50 = 1 uM GNK C15 H18 Cl N O c1cc(ccc1C....
4 5ICJ - 69Y C17 H19 F3 N2 O2 c1ccc(cc1)....
5 5N7O - 69Y C17 H19 F3 N2 O2 c1ccc(cc1)....
6 6HRZ - GO2 C8 H8 N4 S [H]/N=C(/N....
7 6HRY - GOE C10 H15 N3 O CCCNC(=O)N....
8 6HS1 ic50 = 0.00000001 M GO5 C16 H20 Cl N O c1cc(ccc1C....
9 6HS2 ic50 = 0.00000001 M GNZ C16 H18 F3 N O c1cc(ccc1C....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 266 families.
1 6HRX ic50 = 0.00000001 M GO8 C8 H11 N5 S CC(C)Sc1[n....
2 6HS0 ic50 = 0.00000001 M GNW C11 H15 Cl N2 c1cc(cc(c1....
3 6HRW ic50 = 1 uM GNK C15 H18 Cl N O c1cc(ccc1C....
4 5ICJ - 69Y C17 H19 F3 N2 O2 c1ccc(cc1)....
5 5N7O - 69Y C17 H19 F3 N2 O2 c1ccc(cc1)....
6 6HRZ - GO2 C8 H8 N4 S [H]/N=C(/N....
7 6HRY - GOE C10 H15 N3 O CCCNC(=O)N....
8 6HS1 ic50 = 0.00000001 M GO5 C16 H20 Cl N O c1cc(ccc1C....
9 6HS2 ic50 = 0.00000001 M GNZ C16 H18 F3 N O c1cc(ccc1C....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 220 families.
1 6HRX ic50 = 0.00000001 M GO8 C8 H11 N5 S CC(C)Sc1[n....
2 6HS0 ic50 = 0.00000001 M GNW C11 H15 Cl N2 c1cc(cc(c1....
3 6HRW ic50 = 1 uM GNK C15 H18 Cl N O c1cc(ccc1C....
4 5ICJ - 69Y C17 H19 F3 N2 O2 c1ccc(cc1)....
5 5N7O - 69Y C17 H19 F3 N2 O2 c1ccc(cc1)....
6 6HRZ - GO2 C8 H8 N4 S [H]/N=C(/N....
7 6HRY - GOE C10 H15 N3 O CCCNC(=O)N....
8 6HS1 ic50 = 0.00000001 M GO5 C16 H20 Cl N O c1cc(ccc1C....
9 6HS2 ic50 = 0.00000001 M GNZ C16 H18 F3 N O c1cc(ccc1C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GO8; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 GO8 1 1
2 8WT 0.630435 0.902439
3 3D3 0.509091 0.705882
Similar Ligands (3D)
Ligand no: 1; Ligand: GO8; Similar ligands found: 756
No: Ligand Similarity coefficient
1 6N4 0.9615
2 BDI 0.9497
3 MD6 0.9473
4 N2M 0.9469
5 ZHA 0.9462
6 EYV 0.9460
7 2FX 0.9451
8 3VX 0.9433
9 FF2 0.9409
10 GO2 0.9407
11 7PJ 0.9407
12 ZYQ 0.9401
13 NPA 0.9397
14 N91 0.9371
15 DHY 0.9366
16 EVF 0.9365
17 HBI 0.9352
18 DHC 0.9343
19 9BF 0.9324
20 QIV 0.9321
21 4BX 0.9304
22 EXD 0.9302
23 36E 0.9299
24 0FK 0.9296
25 SG2 0.9293
26 JG8 0.9287
27 ONZ 0.9285
28 N7I 0.9285
29 MAJ 0.9283
30 VXX 0.9282
31 SKF 0.9271
32 CIY 0.9266
33 ZIP 0.9247
34 EYY 0.9243
35 IAC 0.9237
36 8U3 0.9233
37 Y3L 0.9231
38 I2E 0.9231
39 BZ2 0.9231
40 EGR 0.9230
41 EYJ 0.9229
42 IOP 0.9229
43 B41 0.9228
44 SYE 0.9226
45 F4E 0.9218
46 BZE 0.9218
47 V1T 0.9208
48 TSR 0.9207
49 428 0.9202
50 E7S 0.9200
51 ICB 0.9193
52 JND 0.9193
53 GJK 0.9190
54 AX3 0.9188
55 2K8 0.9187
56 YTX 0.9186
57 6Q3 0.9185
58 ALE 0.9183
59 XDE 0.9183
60 ZEC 0.9177
61 D8Q 0.9168
62 LDP 0.9167
63 JF1 0.9166
64 H4E 0.9164
65 R9Y 0.9163
66 ZYR 0.9162
67 9ZE 0.9162
68 TMG 0.9159
69 N1E 0.9159
70 UFO 0.9153
71 8XL 0.9153
72 G6P 0.9149
73 AC2 0.9149
74 KTW 0.9147
75 15N 0.9143
76 FER 0.9142
77 0JD 0.9142
78 E1T 0.9139
79 H4B 0.9139
80 61M 0.9137
81 8Y7 0.9134
82 N8Y 0.9134
83 N2I 0.9133
84 ZEZ 0.9133
85 HA5 0.9133
86 C9M 0.9132
87 PH2 0.9131
88 8ZE 0.9129
89 MXD 0.9128
90 4XF 0.9128
91 7AP 0.9127
92 1PS 0.9127
93 ESI 0.9126
94 PLP 0.9126
95 ABF 0.9124
96 ESP 0.9120
97 TSS 0.9118
98 XCG 0.9116
99 HHR 0.9116
100 0W1 0.9116
101 7PS 0.9112
102 BSA 0.9111
103 ESX 0.9108
104 APS 0.9105
105 8HC 0.9104
106 8W9 0.9104
107 7MX 0.9104
108 S7G 0.9102
109 BPY 0.9098
110 CH9 0.9098
111 SRO 0.9097
112 M5H 0.9094
113 TRP 0.9094
114 3VQ 0.9094
115 5E5 0.9091
116 RSV 0.9086
117 BGP 0.9086
118 5B2 0.9085
119 5TY 0.9085
120 KMY 0.9083
121 42J 0.9082
122 H7Y 0.9081
123 SNO 0.9080
124 AEH 0.9079
125 6QF 0.9077
126 6FZ 0.9071
127 GNM 0.9069
128 ZON 0.9066
129 PLR 0.9065
130 LTN 0.9064
131 7I2 0.9064
132 F2W 0.9063
133 ARP 0.9062
134 IOS 0.9061
135 X0U 0.9060
136 2UD 0.9058
137 8NX 0.9058
138 QBM 0.9057
139 1M2 0.9055
140 4WL 0.9053
141 IL5 0.9051
142 6HP 0.9051
143 4BY 0.9048
144 2O6 0.9048
145 ZSP 0.9047
146 3XH 0.9046
147 9FE 0.9046
148 JP2 0.9046
149 2BG 0.9045
150 1F1 0.9044
151 SLS 0.9043
152 KDV 0.9043
153 HHS 0.9042
154 ZZZ 0.9042
155 JF2 0.9041
156 BIO 0.9039
157 QME 0.9039
158 AN3 0.9036
159 XQI 0.9032
160 C9E 0.9031
161 9F8 0.9030
162 M78 0.9029
163 GZ2 0.9025
164 A5P 0.9025
165 J6W 0.9024
166 2HC 0.9024
167 ZRK 0.9023
168 MUK 0.9023
169 XI7 0.9022
170 KLV 0.9021
171 3ZB 0.9019
172 0SY 0.9019
173 MUX 0.9019
174 AMR 0.9019
175 DTR 0.9017
176 LNR 0.9017
177 MPP 0.9017
178 9CA 0.9016
179 8NB 0.9016
180 4AB 0.9015
181 4NZ 0.9013
182 JTH 0.9010
183 2KU 0.9009
184 L21 0.9008
185 12T 0.9005
186 TZM 0.9004
187 CXH 0.9003
188 P1J 0.9001
189 FCD 0.8999
190 BQ2 0.8999
191 X04 0.8998
192 PBN 0.8996
193 BG6 0.8995
194 P80 0.8995
195 GJP 0.8994
196 F5C 0.8993
197 B21 0.8991
198 ANC 0.8991
199 FYR 0.8991
200 H2B 0.8987
201 EOL 0.8986
202 4Z9 0.8984
203 1A7 0.8983
204 DAH 0.8983
205 4BL 0.8983
206 0HN 0.8983
207 LVD 0.8982
208 L22 0.8981
209 4AU 0.8981
210 4FE 0.8980
211 CTE 0.8980
212 535 0.8980
213 9FL 0.8976
214 ZME 0.8976
215 GOE 0.8976
216 X48 0.8974
217 P9E 0.8973
218 HRM 0.8973
219 15E 0.8973
220 KYN 0.8971
221 3EB 0.8968
222 M6P 0.8967
223 RNO 0.8967
224 S0D 0.8966
225 5WU 0.8964
226 C2Y 0.8961
227 BCU 0.8961
228 1IT 0.8960
229 BHS 0.8959
230 H35 0.8959
231 9UL 0.8957
232 KF5 0.8957
233 2QV 0.8955
234 4LW 0.8954
235 NAG 0.8952
236 363 0.8951
237 PIQ 0.8951
238 EUE 0.8950
239 PPY 0.8950
240 MPV 0.8950
241 ZZA 0.8949
242 YOF 0.8948
243 MFZ 0.8948
244 4NP 0.8947
245 ZEA 0.8947
246 ATX 0.8944
247 6NT 0.8944
248 6DP 0.8944
249 EN1 0.8941
250 3IL 0.8940
251 68A 0.8939
252 2ZM 0.8936
253 IPD 0.8935
254 9R5 0.8934
255 ITE 0.8934
256 3H2 0.8933
257 36M 0.8933
258 0HO 0.8933
259 JAW 0.8932
260 7ZL 0.8932
261 5WT 0.8932
262 A7H 0.8932
263 EQA 0.8932
264 UNJ 0.8931
265 XRS 0.8931
266 M4E 0.8931
267 C0W 0.8931
268 HSX 0.8930
269 LL1 0.8929
270 AY4 0.8929
271 3VW 0.8928
272 BP7 0.8928
273 1QV 0.8927
274 5WS 0.8926
275 6HO 0.8925
276 N0Z 0.8924
277 PMP 0.8924
278 2FQ 0.8923
279 5WN 0.8923
280 0J5 0.8922
281 54X 0.8919
282 1VK 0.8919
283 PBA 0.8919
284 27B 0.8918
285 DTE 0.8916
286 TCA 0.8916
287 NVU 0.8916
288 BVA 0.8915
289 YE6 0.8915
290 344 0.8915
291 1QP 0.8912
292 92P 0.8912
293 QX4 0.8912
294 5VU 0.8911
295 DEE 0.8909
296 3Y7 0.8909
297 5GT 0.8909
298 F52 0.8908
299 DNF 0.8908
300 AJV 0.8908
301 M02 0.8907
302 R2P 0.8906
303 D3G 0.8904
304 NEU 0.8902
305 HPT 0.8901
306 PUE 0.8900
307 5NI 0.8900
308 TCR 0.8899
309 E35 0.8899
310 HBO 0.8898
311 4MB 0.8898
312 MR1 0.8898
313 YO5 0.8897
314 3Z8 0.8896
315 MPU 0.8895
316 JB8 0.8895
317 BGU 0.8894
318 3NY 0.8893
319 3SU 0.8892
320 NLA 0.8891
321 ODK 0.8890
322 4R1 0.8890
323 YF3 0.8890
324 XFE 0.8890
325 3A9 0.8889
326 6NI 0.8888
327 EUH 0.8888
328 1SS 0.8887
329 MP5 0.8884
330 BZQ 0.8884
331 55D 0.8882
332 FC2 0.8882
333 SB7 0.8881
334 NBG 0.8881
335 EV2 0.8878
336 P7Y 0.8878
337 IWT 0.8878
338 S60 0.8877
339 30G 0.8876
340 HCI 0.8876
341 HC4 0.8875
342 FWD 0.8874
343 14W 0.8874
344 2LT 0.8874
345 1FE 0.8874
346 OSB 0.8873
347 FZM 0.8873
348 QH3 0.8873
349 795 0.8873
350 K4V 0.8872
351 0FR 0.8869
352 6J9 0.8868
353 6KT 0.8868
354 STT 0.8867
355 QMS 0.8867
356 27K 0.8867
357 GXG 0.8866
358 XEN 0.8866
359 8WO 0.8866
360 LSQ 0.8865
361 PO6 0.8864
362 6FB 0.8864
363 S0E 0.8864
364 4V2 0.8863
365 CWS 0.8863
366 TZP 0.8862
367 ABI 0.8861
368 PRO GLY 0.8860
369 6ME 0.8860
370 JCZ 0.8859
371 3R4 0.8859
372 KTJ 0.8858
373 6VD 0.8858
374 M3Q 0.8858
375 22L 0.8858
376 5F5 0.8858
377 5OB 0.8857
378 GVY 0.8857
379 JDN 0.8857
380 S8D 0.8855
381 0XT 0.8855
382 0DF 0.8854
383 4KL 0.8854
384 XDK 0.8854
385 78P 0.8852
386 3QV 0.8851
387 MMS 0.8850
388 GB4 0.8850
389 G14 0.8850
390 1L5 0.8850
391 4CM 0.8849
392 DQU 0.8848
393 AP6 0.8845
394 RKV 0.8844
395 BL0 0.8844
396 FSU 0.8843
397 848 0.8842
398 HA6 0.8841
399 GZV 0.8841
400 3LJ 0.8841
401 2HU 0.8840
402 2JX 0.8838
403 PXP 0.8838
404 M1Z 0.8837
405 B2J 0.8837
406 B62 0.8837
407 IYR 0.8837
408 NAL 0.8837
409 2P3 0.8837
410 NFZ 0.8836
411 XIZ 0.8836
412 VNL 0.8835
413 3R6 0.8835
414 NQH 0.8835
415 RA7 0.8835
416 HX4 0.8833
417 BZ3 0.8832
418 CK2 0.8832
419 C0H 0.8832
420 8YH 0.8832
421 4I8 0.8830
422 4RU 0.8830
423 CHQ 0.8827
424 TYR 0.8827
425 YPN 0.8826
426 5JT 0.8826
427 0J4 0.8825
428 PNP 0.8824
429 GA2 0.8824
430 B5A 0.8824
431 GXD 0.8823
432 B4O 0.8823
433 B56 0.8823
434 DRG 0.8822
435 GLP 0.8822
436 39O 0.8821
437 FDR 0.8820
438 BB4 0.8820
439 ZRL 0.8819
440 MQB 0.8819
441 DXK 0.8818
442 D2G 0.8818
443 5RO 0.8817
444 KWB 0.8817
445 6L6 0.8816
446 YZM 0.8816
447 1HN 0.8816
448 4OG 0.8813
449 JYT 0.8813
450 AA 0.8812
451 TB8 0.8812
452 3J8 0.8812
453 AH9 0.8810
454 PRF 0.8810
455 BNF 0.8809
456 KP2 0.8809
457 KUF 0.8808
458 L99 0.8808
459 MS0 0.8807
460 AM4 0.8806
461 KLS 0.8805
462 PJW 0.8805
463 EV0 0.8803
464 4ZD 0.8801
465 2QU 0.8800
466 NIY 0.8800
467 0NX 0.8799
468 CWD 0.8798
469 12R 0.8798
470 EMZ 0.8798
471 0FO 0.8796
472 PPT 0.8796
473 MES 0.8795
474 ITW 0.8795
475 LJ4 0.8794
476 5XC 0.8793
477 R9G 0.8792
478 ANF 0.8791
479 S24 0.8790
480 258 0.8790
481 YE7 0.8790
482 K3Q 0.8789
483 4NS 0.8789
484 LJ3 0.8788
485 657 0.8787
486 CUH 0.8787
487 1SV 0.8786
488 D6G 0.8786
489 MQG 0.8786
490 CX4 0.8786
491 X0T 0.8786
492 CR1 0.8784
493 1HR 0.8782
494 94W 0.8782
495 AZY 0.8782
496 BPU 0.8781
497 6MW 0.8780
498 3N0 0.8780
499 NEO 0.8779
500 2HQ 0.8778
501 78Y 0.8777
502 A5E 0.8777
503 F31 0.8777
504 GNW 0.8776
505 3D8 0.8776
506 MBP 0.8775
507 LIP 0.8775
508 78U 0.8774
509 4YO 0.8773
510 6J5 0.8773
511 F9Y 0.8772
512 6C8 0.8770
513 JXK 0.8770
514 M01 0.8770
515 2GQ 0.8770
516 BIK 0.8769
517 96Z 0.8768
518 2WU 0.8768
519 N9J 0.8768
520 PMM 0.8768
521 7MW 0.8767
522 0P6 0.8766
523 F06 0.8765
524 NBV 0.8765
525 0TU 0.8765
526 7O4 0.8764
527 4CN 0.8763
528 XHP 0.8760
529 C4E 0.8760
530 263 0.8759
531 A5H 0.8759
532 2LW 0.8759
533 AJ1 0.8758
534 M3E 0.8756
535 CC5 0.8756
536 VM1 0.8756
537 RCV 0.8756
538 AJY 0.8755
539 SJK 0.8754
540 FT6 0.8753
541 FQX 0.8751
542 0UL 0.8750
543 3TC 0.8750
544 E3X 0.8750
545 67Y 0.8750
546 A9B 0.8746
547 X11 0.8745
548 7VP 0.8745
549 7EH 0.8743
550 44V 0.8742
551 G1P 0.8741
552 TWO 0.8741
553 HL4 0.8741
554 PLP PMP 0.8741
555 PZP 0.8741
556 833 0.8741
557 2JK 0.8739
558 B2E 0.8738
559 QIF 0.8737
560 WA2 0.8736
561 EXL 0.8736
562 DBS 0.8736
563 7L4 0.8733
564 92O 0.8731
565 EE8 0.8730
566 S98 0.8729
567 M6D 0.8729
568 OOG 0.8727
569 92G 0.8727
570 1Z6 0.8727
571 6ZW 0.8727
572 AJG 0.8725
573 5F8 0.8725
574 5V7 0.8721
575 4FF 0.8721
576 5OO 0.8720
577 NFM 0.8720
578 TU0 0.8720
579 6C9 0.8719
580 9NB 0.8718
581 SQ7 0.8718
582 EQW 0.8717
583 TOH 0.8716
584 8TX 0.8715
585 PPN 0.8715
586 PRZ 0.8715
587 AZM 0.8715
588 8G6 0.8715
589 ETV 0.8714
590 LZ5 0.8713
591 2D2 0.8713
592 3IP 0.8712
593 FK8 0.8712
594 3IB 0.8712
595 F40 0.8712
596 2LY 0.8712
597 QUB 0.8711
598 S7D 0.8710
599 GHM 0.8710
600 KCH 0.8710
601 28S 0.8708
602 ZIQ 0.8708
603 OA1 0.8707
604 8IG 0.8706
605 BK9 0.8706
606 GDL 0.8705
607 UAN 0.8705
608 FHC 0.8703
609 RVE 0.8703
610 A6W 0.8702
611 P81 0.8701
612 R4E 0.8700
613 PEY 0.8700
614 4XS 0.8699
615 I3E 0.8698
616 CFA 0.8697
617 O2Y 0.8696
618 B61 0.8695
619 ALN 0.8695
620 774 0.8692
621 GRX 0.8692
622 I4D 0.8691
623 JXT 0.8690
624 4A5 0.8690
625 PQT 0.8689
626 DEW 0.8689
627 4TB 0.8688
628 HPP 0.8688
629 28N 0.8688
630 9GP 0.8688
631 505 0.8688
632 5NN 0.8686
633 5GV 0.8686
634 ZYV 0.8685
635 5AD 0.8685
636 9JT 0.8683
637 EWG 0.8682
638 WSD 0.8682
639 0XR 0.8681
640 MVN 0.8680
641 F6P 0.8678
642 4NM 0.8677
643 E9S 0.8676
644 CUT 0.8676
645 F1X 0.8675
646 IQ5 0.8675
647 OTW 0.8674
648 3GX 0.8672
649 ENO 0.8671
650 CWJ 0.8671
651 IBP 0.8671
652 S0G 0.8671
653 6C5 0.8671
654 6ZX 0.8671
655 5GU 0.8670
656 TXW 0.8668
657 WS7 0.8666
658 0LH 0.8665
659 259 0.8665
660 TIA 0.8665
661 SWX 0.8662
662 D1G 0.8662
663 U13 0.8662
664 268 0.8661
665 CXP 0.8659
666 6FG 0.8658
667 FUZ 0.8657
668 YIE 0.8657
669 J0Z 0.8657
670 K37 0.8656
671 C82 0.8656
672 264 0.8655
673 HXY 0.8655
674 ASE 0.8654
675 4VS 0.8653
676 4Z1 0.8650
677 JY2 0.8649
678 JOV 0.8648
679 22T 0.8647
680 C53 0.8645
681 1EB 0.8645
682 1X4 0.8644
683 TA6 0.8642
684 SNY 0.8640
685 E1P 0.8640
686 AOT 0.8639
687 B5D 0.8638
688 QUS 0.8637
689 M6Z 0.8634
690 1ZC 0.8633
691 5DL 0.8632
692 B55 0.8631
693 PRL 0.8631
694 HNT 0.8630
695 SQ4 0.8630
696 Q5M 0.8629
697 DTY 0.8627
698 5FL 0.8626
699 3VS 0.8621
700 BHQ 0.8621
701 SXX 0.8617
702 M6H 0.8617
703 A6P 0.8616
704 MUR 0.8614
705 JRB 0.8612
706 20J 0.8609
707 LEL 0.8607
708 5LD 0.8607
709 1P7 0.8605
710 IPT 0.8605
711 3QO 0.8605
712 UN1 0.8604
713 5B1 0.8603
714 2J5 0.8603
715 AVX 0.8602
716 J38 0.8599
717 GB5 0.8597
718 HNM 0.8596
719 372 0.8594
720 NIP 0.8593
721 0OK 0.8592
722 CWM 0.8588
723 8MP 0.8587
724 RD4 0.8585
725 FPL 0.8581
726 2PV 0.8578
727 4TP 0.8575
728 LO1 0.8575
729 RGG 0.8574
730 L15 0.8568
731 ZZU 0.8564
732 DT7 0.8564
733 CKA 0.8563
734 LZ2 0.8562
735 2CZ 0.8562
736 WLH 0.8562
737 E4P 0.8561
738 EYM 0.8560
739 9VQ 0.8559
740 M3P 0.8558
741 64E 0.8557
742 7FU 0.8557
743 OW7 0.8556
744 NK5 0.8555
745 OVP 0.8549
746 MJ5 0.8549
747 DE7 0.8542
748 5JL 0.8541
749 UAY 0.8539
750 UA5 0.8537
751 HL6 0.8537
752 CS2 0.8526
753 JGB 0.8524
754 AOY 0.8519
755 HHV 0.8518
756 F90 0.8518
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6HS2; Ligand: GNZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6hs2.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
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