Receptor
PDB id Resolution Class Description Source Keywords
6JZ3 1.5 Å EC: 3.-.-.- B-GLUCURONIDASE FROM RUMINOCOCCUS GNAVUS IN COMPLEX WITH URO DEOXYNOJIRIMYCIN RUMINOCOCCUS GNAVUS B-GLUCURONIDASE HYDROLASE
Ref.: SUBSTITUENT POSITION OF IMINOCYCLITOLS DETERMINES T POTENCY AND SELECTIVITY FOR GUT MICROBIAL XENOBIOTIC-REACTIVATING ENZYMES. J.MED.CHEM. V. 63 4617 2020
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MRD B:702;
 Invalid;
 none;
 submit data
118.174 C6 H14 O2 C[C@H...
CN0 A:701;
B:701;
 Valid;
Valid;
 none;
none;
 submit data
177.155 C6 H11 N O5 C1[C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6JZ2 1.29 Å EC: 3.-.-.- B-GLUCURONIDASE FROM RUMINOCOCCUS GNAVUS IN COMPLEX WITH URO ISOFAGOMINE AT 1.3 ANGSTROMS RESOLUTION RUMINOCOCCUS GNAVUS B-GLUCURONIDASE HYDROLASE
Ref.: SUBSTITUENT POSITION OF IMINOCYCLITOLS DETERMINES T POTENCY AND SELECTIVITY FOR GUT MICROBIAL XENOBIOTIC-REACTIVATING ENZYMES. J.MED.CHEM. V. 63 4617 2020
Members (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 312 families.
1 6JZ5 - BDP C6 H10 O7 [C@@H]1([C....
2 6JZ7 - CKU C9 H17 N O4 CCCN1C[C@@....
3 6JZ3 - CN0 C6 H11 N O5 C1[C@@H]([....
4 6JZ4 - EVA C6 H9 N O6 [C@@H]1([C....
5 6JZ6 - CKX C9 H17 N O4 CCC[C@H]1[....
6 6JZ8 - GCB C6 H8 O7 [C@@H]1([C....
7 6JZ2 - SJ5 C6 H11 N O4 C1[C@@H]([....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 261 families.
1 6JZ5 - BDP C6 H10 O7 [C@@H]1([C....
2 6JZ7 - CKU C9 H17 N O4 CCCN1C[C@@....
3 6JZ3 - CN0 C6 H11 N O5 C1[C@@H]([....
4 6JZ4 - EVA C6 H9 N O6 [C@@H]1([C....
5 6JZ6 - CKX C9 H17 N O4 CCC[C@H]1[....
6 6JZ8 - GCB C6 H8 O7 [C@@H]1([C....
7 6JZ2 - SJ5 C6 H11 N O4 C1[C@@H]([....
50% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 214 families.
1 3K4D Ki = 7750 nM EVA C6 H9 N O6 [C@@H]1([C....
2 5CZK Ki = 1.9 uM 57Z C21 H23 N3 O3 S Cc1cc(c2c(....
3 3LPF Ki = 208 nM Z77 C22 H25 N3 O3 S Cc1cc2c(cc....
4 6JZ5 - BDP C6 H10 O7 [C@@H]1([C....
5 6JZ7 - CKU C9 H17 N O4 CCCN1C[C@@....
6 6JZ3 - CN0 C6 H11 N O5 C1[C@@H]([....
7 6JZ4 - EVA C6 H9 N O6 [C@@H]1([C....
8 6JZ6 - CKX C9 H17 N O4 CCC[C@H]1[....
9 6JZ8 - GCB C6 H8 O7 [C@@H]1([C....
10 6JZ2 - SJ5 C6 H11 N O4 C1[C@@H]([....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: CN0; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 CN0 1 1
2 8WQ 0.425 0.794872
3 HY3 0.4 0.775
Similar Ligands (3D)
Ligand no: 1; Ligand: CN0; Similar ligands found: 1118
No: Ligand Similarity coefficient
1 BDP 0.9935
2 DOB 0.9785
3 GCU 0.9765
4 4AA 0.9759
5 DBH 0.9749
6 GCB 0.9748
7 IFL 0.9711
8 NOJ 0.9703
9 5CU 0.9702
10 ASO 0.9693
11 FA0 0.9687
12 G2F 0.9686
13 NOY 0.9682
14 DHB 0.9681
15 SJ5 0.9677
16 3HA 0.9653
17 BHA 0.9651
18 93K 0.9650
19 EVA 0.9647
20 LCN 0.9643
21 IJZ 0.9642
22 GLC 0.9638
23 4M0 0.9634
24 5QX 0.9633
25 3IT 0.9631
26 MYJ 0.9620
27 P9P 0.9608
28 INO 0.9596
29 BGC 0.9588
30 5NU 0.9586
31 K5W 0.9569
32 4NC 0.9558
33 FOT 0.9557
34 QSB 0.9555
35 SHG 0.9554
36 VNL 0.9554
37 3M0 0.9548
38 3F0 0.9533
39 DHK 0.9529
40 9TW 0.9529
41 MNM 0.9523
42 PA1 0.9512
43 CHB 0.9512
44 2HO 0.9510
45 LGC 0.9508
46 ADA 0.9496
47 TTL 0.9493
48 3FH 0.9492
49 G3F 0.9487
50 GDE 0.9487
51 6F0 0.9482
52 PXL 0.9481
53 NPO 0.9479
54 GTR 0.9478
55 IHB 0.9477
56 VNJ 0.9475
57 HQD 0.9475
58 SOE 0.9466
59 BE2 0.9462
60 SAL 0.9458
61 IFP 0.9457
62 B57 0.9453
63 GAB 0.9449
64 GCS 0.9440
65 CFF 0.9440
66 FYU 0.9439
67 AC6 0.9435
68 GCV 0.9430
69 J9W 0.9426
70 QSH 0.9424
71 PHB 0.9423
72 KJY 0.9422
73 3U4 0.9416
74 UEG 0.9415
75 HHA 0.9413
76 GAL 0.9408
77 ES6 0.9408
78 GRE 0.9408
79 SKM 0.9406
80 HMU 0.9405
81 L99 0.9404
82 8WO 0.9404
83 KOJ 0.9398
84 PXM 0.9396
85 KJU 0.9394
86 IPB 0.9392
87 FBV 0.9390
88 3NT 0.9388
89 URC 0.9386
90 94B 0.9385
91 BZX 0.9385
92 GXL 0.9382
93 PAB 0.9381
94 ZXD 0.9380
95 3WA 0.9375
96 IFM 0.9373
97 ORO 0.9372
98 5RO 0.9372
99 INE 0.9372
100 1F1 0.9364
101 DIU 0.9363
102 ICO 0.9363
103 8S0 0.9362
104 BMA 0.9362
105 HXX 0.9361
106 4HC 0.9361
107 MAN 0.9358
108 8H8 0.9355
109 I3A 0.9347
110 3PF 0.9346
111 SVD 0.9342
112 5RN 0.9342
113 4P5 0.9342
114 PBZ 0.9341
115 GCW 0.9340
116 X0V 0.9339
117 82I 0.9336
118 SRT 0.9336
119 5RG 0.9335
120 FBT 0.9333
121 HBD 0.9333
122 KBG 0.9331
123 948 0.9330
124 FE DB1 0.9329
125 6M1 0.9324
126 F31 0.9322
127 Z5P 0.9320
128 JKE 0.9320
129 AHR 0.9319
130 ZZT 0.9319
131 3HB 0.9318
132 XX2 0.9317
133 EKZ 0.9317
134 4JQ 0.9317
135 BZ3 0.9314
136 PNZ 0.9313
137 0HO 0.9311
138 D1X 0.9307
139 JLZ 0.9307
140 CLZ 0.9305
141 SYV 0.9302
142 OXZ 0.9300
143 GTQ 0.9299
144 9DG 0.9299
145 XAN 0.9297
146 2FY 0.9295
147 JTH 0.9294
148 M1Q 0.9294
149 SYA 0.9293
150 42C 0.9292
151 8TX 0.9289
152 R8V 0.9287
153 Q6T 0.9286
154 3XX 0.9285
155 MS9 0.9283
156 Z82 0.9280
157 LXC 0.9279
158 C2U 0.9279
159 4MA 0.9277
160 1LQ 0.9275
161 GIV 0.9275
162 9PY 0.9272
163 G4D 0.9272
164 53C 0.9271
165 AFR 0.9270
166 TH7 0.9267
167 2ZM 0.9266
168 4A3 0.9265
169 5M0 0.9264
170 GUN 0.9264
171 OVV 0.9263
172 GLT 0.9262
173 DFB 0.9260
174 DGJ 0.9257
175 4XV 0.9257
176 7ZE 0.9257
177 V55 0.9256
178 J9Q 0.9256
179 92K 0.9256
180 FB1 0.9255
181 1P8 0.9255
182 MT5 0.9254
183 3OC 0.9252
184 KFH 0.9252
185 15L 0.9251
186 EUG 0.9251
187 ASC 0.9250
188 PFB 0.9250
189 9TZ 0.9250
190 GLU 0.9250
191 GLA 0.9248
192 LYL 0.9247
193 5QY 0.9247
194 CTS 0.9247
195 BNT 0.9247
196 B62 0.9247
197 FHB 0.9246
198 54G 0.9246
199 HMH 0.9245
200 F1A 0.9242
201 NSP 0.9240
202 97T 0.9237
203 RHU 0.9236
204 HBA 0.9236
205 DOR 0.9235
206 P72 0.9235
207 X05 0.9234
208 GAF 0.9231
209 GLF 0.9229
210 F05 0.9229
211 2H5 0.9228
212 SWA 0.9228
213 3A9 0.9228
214 WOO 0.9227
215 ANN 0.9227
216 ZB1 0.9225
217 3MG 0.9224
218 BEZ 0.9224
219 5GU 0.9222
220 4FH 0.9221
221 0R0 0.9220
222 3HM 0.9219
223 OXC 0.9218
224 BDF 0.9217
225 XYP 0.9215
226 AZF 0.9215
227 ODO 0.9214
228 4YO 0.9213
229 H42 0.9212
230 0HN 0.9211
231 1Y6 0.9208
232 JBK 0.9207
233 4SX 0.9207
234 DMJ 0.9206
235 FCR 0.9206
236 XXP 0.9205
237 VK3 0.9204
238 QX4 0.9204
239 5NI 0.9203
240 Q24 0.9201
241 GZL 0.9199
242 OA3 0.9198
243 DQU 0.9197
244 LT2 0.9196
245 6NT 0.9195
246 5DI 0.9193
247 3Z8 0.9192
248 2KA 0.9190
249 E7Z 0.9189
250 KGK 0.9189
251 SHA 0.9188
252 24B 0.9188
253 717 0.9187
254 AKH 0.9186
255 C2Y 0.9186
256 PBC 0.9184
257 5XC 0.9183
258 E5X 0.9183
259 9FL 0.9182
260 2FG 0.9181
261 3NY 0.9181
262 L7T 0.9180
263 7HQ 0.9180
264 0FN 0.9179
265 0P6 0.9179
266 B53 0.9177
267 GYE 0.9175
268 RAT 0.9174
269 UFV 0.9174
270 DHS 0.9173
271 12Q 0.9173
272 5MK 0.9173
273 F81 0.9172
274 7B4 0.9172
275 23J 0.9171
276 ABI 0.9170
277 BHO 0.9168
278 6NI 0.9168
279 LNR 0.9167
280 HNQ 0.9166
281 RPQ 0.9166
282 NNO 0.9165
283 DMD 0.9165
284 GJP 0.9165
285 M1E 0.9164
286 5OB 0.9164
287 XIY 0.9164
288 LDP 0.9163
289 MZB 0.9162
290 ISZ 0.9162
291 NCA 0.9158
292 NBZ 0.9158
293 PZI 0.9157
294 173 0.9157
295 261 0.9154
296 4Z4 0.9152
297 CFI 0.9152
298 KJH 0.9151
299 8XQ 0.9151
300 2EC 0.9149
301 7VS 0.9149
302 4XS 0.9148
303 D48 0.9148
304 6M4 0.9147
305 IP0 0.9145
306 2CK 0.9145
307 JAW 0.9144
308 23A 0.9143
309 ES2 0.9143
310 4XR 0.9142
311 7W1 0.9142
312 7B3 0.9141
313 4WL 0.9140
314 3RK 0.9136
315 7N0 0.9136
316 G3E 0.9135
317 TTY 0.9131
318 4VP 0.9131
319 FA1 0.9130
320 NIO 0.9126
321 HLZ 0.9125
322 UNU 0.9124
323 KKN 0.9123
324 COU 0.9122
325 DFU 0.9122
326 TSU 0.9121
327 2CL 0.9119
328 7ME 0.9116
329 3DM 0.9115
330 3ID 0.9114
331 R9S 0.9114
332 3SK 0.9112
333 MO8 0.9111
334 K17 0.9111
335 PZA 0.9111
336 X6X 0.9110
337 51R 0.9110
338 HPA 0.9109
339 7WV 0.9108
340 NAG 0.9108
341 FAN 0.9108
342 1WC 0.9107
343 1GN 0.9105
344 P3K 0.9103
345 NIZ 0.9102
346 1KP 0.9102
347 JZ3 0.9101
348 ISN 0.9100
349 5WV 0.9099
350 LKA 0.9098
351 44V 0.9097
352 HDH 0.9097
353 ALL 0.9097
354 FBM 0.9096
355 PRZ 0.9096
356 A7W 0.9095
357 FP1 0.9095
358 BTE 0.9095
359 57O 0.9095
360 URF 0.9095
361 4RU 0.9094
362 6ME 0.9093
363 FRU 0.9091
364 PHU 0.9091
365 HH5 0.9088
366 HJP 0.9086
367 4HM 0.9086
368 QIC 0.9086
369 680 0.9084
370 G5V 0.9081
371 293 0.9081
372 2AL 0.9080
373 6CS 0.9080
374 YIO 0.9079
375 SE2 0.9079
376 15E 0.9078
377 QWN 0.9077
378 6PC 0.9076
379 AMH 0.9075
380 A13 0.9074
381 N2I 0.9074
382 J9T 0.9073
383 N3W 0.9072
384 1U6 0.9069
385 UNC 0.9069
386 RIP 0.9069
387 AW5 0.9068
388 M0Q 0.9066
389 SOR 0.9065
390 DQA 0.9065
391 DBX 0.9064
392 FUD 0.9064
393 TYL 0.9063
394 ES7 0.9061
395 449 0.9061
396 IF7 0.9060
397 R9Y 0.9060
398 WBU 0.9058
399 VOH 0.9058
400 Q88 0.9056
401 T9G 0.9055
402 DIN 0.9054
403 HQT 0.9054
404 KBB 0.9053
405 DQN 0.9052
406 TAG 0.9051
407 4NG 0.9051
408 TGX 0.9051
409 8WT 0.9050
410 3BZ 0.9050
411 BZ2 0.9050
412 149 0.9048
413 7W4 0.9048
414 25W 0.9048
415 4SV 0.9047
416 34D 0.9047
417 FGZ 0.9046
418 286 0.9044
419 BAM 0.9041
420 HQJ 0.9041
421 03V 0.9040
422 SW7 0.9039
423 SAN 0.9038
424 NGT 0.9037
425 4CS 0.9036
426 BPN 0.9036
427 6FZ 0.9034
428 1LN 0.9034
429 NK 0.9033
430 SS1 0.9033
431 4FS 0.9032
432 12T 0.9031
433 ADE 0.9031
434 H62 0.9031
435 XXR 0.9030
436 VXX 0.9029
437 F0J 0.9029
438 P84 0.9029
439 XX3 0.9028
440 JB5 0.9026
441 M2K 0.9026
442 9MG 0.9025
443 EA1 0.9024
444 OCH 0.9024
445 2AQ 0.9022
446 42J 0.9021
447 2LP 0.9020
448 XYS 0.9016
449 XCZ 0.9016
450 X09 0.9014
451 NDH 0.9013
452 ES5 0.9013
453 M1H 0.9012
454 15N 0.9012
455 QY9 0.9012
456 2CZ 0.9010
457 MBG 0.9010
458 FCA 0.9010
459 TEP 0.9010
460 EYK 0.9009
461 PD2 0.9009
462 K3Q 0.9008
463 CTL 0.9007
464 JDN 0.9007
465 1SQ 0.9006
466 4ME 0.9005
467 OAA 0.9005
468 52C 0.9004
469 XM0 0.9003
470 WCE 0.9002
471 4NM 0.9002
472 5SG 0.9000
473 EPR 0.9000
474 3MB 0.9000
475 N2Z 0.8997
476 N5J 0.8996
477 0F9 0.8995
478 M0W 0.8994
479 1XA 0.8994
480 86J 0.8993
481 RMN 0.8993
482 PQK 0.8991
483 DEE 0.8991
484 HIS 0.8991
485 4ZA 0.8991
486 5IQ 0.8990
487 1NP 0.8990
488 SX1 0.8990
489 DIE 0.8990
490 O2A 0.8989
491 1WD 0.8988
492 NID 0.8987
493 9KH 0.8987
494 5NS 0.8987
495 BSX 0.8986
496 YSO 0.8986
497 SYG 0.8986
498 BCU 0.8985
499 JPZ 0.8984
500 YCP 0.8984
501 4M4 0.8983
502 0MK 0.8983
503 R8A 0.8983
504 QXW 0.8981
505 OTR 0.8981
506 JBH 0.8980
507 1PT 0.8980
508 K32 0.8980
509 NGO 0.8979
510 3DO 0.8978
511 PYQ 0.8978
512 D3M 0.8978
513 36E 0.8978
514 FDR 0.8978
515 F60 0.8976
516 NQ 0.8976
517 TWO 0.8976
518 ARB 0.8975
519 LSA 0.8975
520 5Q0 0.8974
521 ISE 0.8974
522 4YS 0.8973
523 92P 0.8973
524 NGW 0.8973
525 KYD 0.8973
526 O72 0.8972
527 F9P 0.8972
528 INS 0.8972
529 ES1 0.8971
530 FA3 0.8971
531 4FA 0.8971
532 KP6 0.8970
533 JBQ 0.8969
534 FDK 0.8969
535 PHE 0.8969
536 HQY 0.8968
537 NDG 0.8968
538 FUC 0.8968
539 NTM 0.8968
540 PE0 0.8967
541 1LM 0.8966
542 JB8 0.8966
543 MR1 0.8965
544 NVU 0.8965
545 GJZ 0.8965
546 BNS 0.8965
547 GOG 0.8964
548 TLA 0.8964
549 CXF 0.8964
550 GYP 0.8964
551 AJ2 0.8963
552 MRW 0.8963
553 GF4 0.8963
554 826 0.8962
555 0N7 0.8961
556 QSC 0.8961
557 M5K 0.8961
558 TT4 0.8961
559 3AB 0.8960
560 AEH 0.8959
561 I1N 0.8956
562 4JT 0.8954
563 0LH 0.8954
564 XQ0 0.8954
565 TIU 0.8954
566 OHP 0.8953
567 SN4 0.8952
568 FUL 0.8952
569 1P3 0.8951
570 CWM 0.8950
571 RXA 0.8950
572 NTZ 0.8950
573 ISD 0.8949
574 5WX 0.8948
575 8GC 0.8948
576 PRF 0.8947
577 XXG 0.8946
578 AZ8 0.8946
579 AZ9 0.8946
580 M58 0.8946
581 RIB 0.8945
582 5H1 0.8944
583 MLT 0.8944
584 OVM 0.8944
585 2K4 0.8943
586 9KT 0.8943
587 PEP 0.8943
588 L5V 0.8942
589 0JD 0.8941
590 DHQ 0.8940
591 GTK 0.8939
592 7MU 0.8939
593 FH2 0.8938
594 GIM 0.8938
595 4J8 0.8938
596 7HP 0.8938
597 J5I 0.8937
598 6M9 0.8937
599 60P 0.8937
600 7VJ 0.8937
601 MJ2 0.8937
602 M6N 0.8936
603 4TU 0.8935
604 MEW 0.8934
605 GM7 0.8933
606 27B 0.8932
607 6AI 0.8932
608 174 0.8930
609 PBA 0.8930
610 069 0.8929
611 JBE 0.8929
612 DNF 0.8926
613 PMB 0.8926
614 NMJ 0.8925
615 32X 0.8923
616 9R5 0.8923
617 PAC 0.8919
618 PQ0 0.8919
619 EN1 0.8919
620 HIO 0.8917
621 0W1 0.8917
622 NCT 0.8916
623 8GK 0.8916
624 FUF 0.8916
625 AQO 0.8915
626 MFB 0.8915
627 3C4 0.8915
628 GOX 0.8914
629 5JQ 0.8914
630 TAR 0.8914
631 ADZ 0.8911
632 ONR 0.8911
633 QAS 0.8910
634 67N 0.8908
635 4P0 0.8908
636 7NI 0.8907
637 NPY 0.8907
638 2ZV 0.8905
639 JAE 0.8905
640 FBW 0.8904
641 DBJ 0.8902
642 AEF 0.8902
643 DX3 0.8902
644 RSO 0.8901
645 MQN 0.8901
646 FBS 0.8901
647 T6C 0.8901
648 5HY 0.8900
649 9ZE 0.8900
650 KYA 0.8900
651 AKG 0.8900
652 M1A 0.8898
653 2LY 0.8898
654 QX2 0.8897
655 FDB 0.8897
656 FB2 0.8897
657 6AP 0.8895
658 FBA 0.8895
659 PJW 0.8895
660 FBU 0.8893
661 HY1 0.8892
662 H33 0.8892
663 SRO 0.8892
664 QBK 0.8891
665 HHT 0.8890
666 EV0 0.8890
667 TFU 0.8890
668 ARP 0.8889
669 QWW 0.8889
670 GLO 0.8889
671 EXD 0.8889
672 MSR 0.8889
673 6GU 0.8887
674 4JL 0.8886
675 5HN 0.8885
676 IDM 0.8885
677 9FE 0.8884
678 TPA 0.8884
679 QPR 0.8883
680 AZA 0.8883
681 GZQ 0.8883
682 GVG 0.8883
683 3GQ 0.8883
684 AMG 0.8882
685 AEZ 0.8882
686 YQA 0.8880
687 GOO 0.8880
688 2HQ 0.8879
689 BEA 0.8878
690 QUZ 0.8878
691 CLW 0.8877
692 BEN 0.8877
693 SS2 0.8877
694 FBB 0.8876
695 2BG 0.8876
696 PHT 0.8876
697 CWS 0.8876
698 ZWZ 0.8875
699 AAS 0.8875
700 OW4 0.8875
701 URS 0.8874
702 FIX 0.8874
703 KUF 0.8873
704 AX7 0.8873
705 AMS 0.8872
706 5VL 0.8871
707 LZ2 0.8871
708 YRL 0.8870
709 ET2 0.8869
710 LI6 0.8869
711 HTP 0.8869
712 BTY 0.8869
713 GZ8 0.8869
714 PZM 0.8869
715 259 0.8869
716 CPZ 0.8869
717 OMD 0.8867
718 ABV 0.8867
719 M4S 0.8866
720 H7Y 0.8864
721 EOL 0.8863
722 TSS 0.8863
723 2XX 0.8863
724 FLV 0.8863
725 4MU 0.8862
726 MVL 0.8862
727 141 0.8860
728 FLC 0.8860
729 K2T 0.8860
730 PYG 0.8859
731 EMZ 0.8858
732 AZG 0.8857
733 LAO 0.8857
734 2ZQ 0.8857
735 GJS 0.8856
736 14O 0.8855
737 3Z7 0.8855
738 XHP 0.8854
739 64K 0.8854
740 428 0.8854
741 0TU 0.8853
742 APZ 0.8852
743 2MI 0.8849
744 1XM 0.8849
745 G6D 0.8847
746 37T 0.8847
747 GXY 0.8847
748 F12 0.8847
749 PH2 0.8847
750 YH7 0.8846
751 4XH 0.8846
752 TOF 0.8846
753 0CU 0.8846
754 06B 0.8845
755 AIN 0.8843
756 3CU 0.8842
757 PHH 0.8842
758 6VD 0.8842
759 EXO 0.8842
760 SVN 0.8841
761 44W 0.8841
762 8CM 0.8840
763 2HU 0.8839
764 3R6 0.8839
765 CWJ 0.8839
766 LZM 0.8838
767 DS0 0.8838
768 5WY 0.8838
769 HDL 0.8838
770 ROR 0.8837
771 JZ1 0.8837
772 24W 0.8837
773 IGA 0.8836
774 JZ4 0.8835
775 7WR 0.8835
776 LMR 0.8834
777 RM1 0.8833
778 TNX 0.8832
779 PRY 0.8832
780 DHY 0.8832
781 QAT 0.8832
782 0FO 0.8832
783 ROI 0.8831
784 XAZ 0.8831
785 A29 0.8831
786 95Z 0.8831
787 7MH 0.8831
788 KTA 0.8830
789 DRL 0.8830
790 JKZ 0.8830
791 Q02 0.8829
792 JFJ 0.8829
793 1AL 0.8828
794 JND 0.8827
795 B55 0.8826
796 GDL 0.8826
797 FHN 0.8826
798 DNA 0.8826
799 ZZ8 0.8824
800 0RW 0.8824
801 GV9 0.8822
802 ARA 0.8819
803 L14 0.8819
804 4VY 0.8819
805 LPK 0.8818
806 A2F 0.8817
807 8ZE 0.8816
808 TBS 0.8815
809 M4E 0.8814
810 329 0.8814
811 2O6 0.8814
812 75K 0.8813
813 2D0 0.8813
814 DX4 0.8812
815 MA3 0.8812
816 W81 0.8812
817 KIB 0.8811
818 94W 0.8809
819 2A9 0.8808
820 PFL 0.8808
821 BRT 0.8808
822 8NX 0.8807
823 1HN 0.8806
824 60Q 0.8806
825 C2B 0.8806
826 HHR 0.8806
827 5MI 0.8805
828 GIF 0.8805
829 IDH 0.8805
830 SOL 0.8804
831 VGD 0.8803
832 IPZ 0.8803
833 3BU 0.8802
834 AGK 0.8801
835 39A 0.8801
836 8W9 0.8801
837 DC5 0.8801
838 6RQ 0.8800
839 RAM 0.8799
840 GAG 0.8799
841 M4T 0.8798
842 270 0.8796
843 ASP 0.8796
844 KLW 0.8794
845 R20 0.8794
846 SEP 0.8793
847 ICB 0.8793
848 VGL 0.8792
849 12B 0.8791
850 42A 0.8791
851 P92 0.8790
852 FCB 0.8789
853 GBD 0.8789
854 HHH 0.8788
855 SR1 0.8787
856 OTW 0.8786
857 1DW 0.8784
858 MSN 0.8783
859 E7S 0.8782
860 MUA 0.8781
861 SYN 0.8781
862 SKA 0.8780
863 MXN 0.8779
864 XDE 0.8779
865 CH9 0.8778
866 9RW 0.8776
867 MCT 0.8774
868 M3H 0.8774
869 BNF 0.8773
870 AC0 0.8772
871 5VM 0.8771
872 11S 0.8771
873 2GS 0.8770
874 F5B 0.8769
875 FEH 0.8769
876 DPZ 0.8768
877 8OZ 0.8766
878 RB5 0.8765
879 KJ5 0.8764
880 B0D 0.8763
881 PIY 0.8762
882 4ZC 0.8761
883 BBK 0.8761
884 NSG 0.8760
885 2AS 0.8760
886 TZE 0.8759
887 I1E 0.8758
888 PIM 0.8758
889 SMN 0.8757
890 EQT 0.8757
891 JG8 0.8757
892 EGR 0.8754
893 REL 0.8754
894 TSR 0.8753
895 OAF 0.8753
896 XYD 0.8752
897 495 0.8752
898 2PG 0.8751
899 JXN 0.8750
900 S24 0.8750
901 7WG 0.8750
902 MT0 0.8749
903 MWP 0.8749
904 260 0.8748
905 SNU 0.8747
906 XUL 0.8745
907 IAC 0.8745
908 UNJ 0.8745
909 1P7 0.8744
910 AX3 0.8744
911 GTL 0.8744
912 CGB 0.8743
913 Q71 0.8742
914 TDR 0.8741
915 1AB 0.8740
916 F4E 0.8740
917 KT7 0.8739
918 5FN 0.8739
919 4JJ 0.8737
920 AL0 0.8737
921 RNS 0.8736
922 ZZ3 0.8736
923 GIO 0.8736
924 1IT 0.8735
925 B5D 0.8735
926 RM4 0.8734
927 0W8 0.8734
928 7D2 0.8733
929 SF9 0.8732
930 ZZZ 0.8732
931 36R 0.8732
932 XQK 0.8732
933 HLR 0.8731
934 3SL 0.8731
935 KDV 0.8731
936 9EW 0.8730
937 NOK 0.8730
938 HA5 0.8730
939 JXZ 0.8728
940 5JL 0.8728
941 HA7 0.8728
942 AJV 0.8727
943 GLN 0.8727
944 2FQ 0.8726
945 UFO 0.8726
946 5MB 0.8725
947 KIA 0.8723
948 4CL 0.8722
949 ARW 0.8722
950 HZQ 0.8720
951 FSW 0.8719
952 QMP 0.8717
953 MVN 0.8717
954 5WU 0.8716
955 FA6 0.8716
956 ADK 0.8712
957 290 0.8712
958 3RI 0.8710
959 BNL 0.8710
960 GLY PRO 0.8709
961 505 0.8709
962 ABN 0.8709
963 XBZ 0.8707
964 1SA 0.8707
965 HKD 0.8706
966 EDR 0.8705
967 APS 0.8703
968 10L 0.8703
969 5NE 0.8702
970 G1O 0.8700
971 IV2 0.8700
972 4HO 0.8699
973 C2A 0.8699
974 2AC 0.8698
975 JZ2 0.8694
976 2TQ 0.8694
977 H4N 0.8693
978 4BZ 0.8693
979 2MN 0.8692
980 CFP 0.8692
981 PEL 0.8691
982 28N 0.8691
983 LT8 0.8690
984 BOA 0.8690
985 PX7 0.8690
986 XQG 0.8689
987 61M 0.8689
988 CIT 0.8689
989 H76 0.8687
990 MMA 0.8687
991 4JM 0.8685
992 HQ9 0.8685
993 6XI 0.8684
994 7MK 0.8683
995 BR9 0.8683
996 2AK 0.8683
997 AMC 0.8681
998 DHR 0.8681
999 PEA 0.8681
1000 36Y 0.8681
1001 9CA 0.8680
1002 HH8 0.8680
1003 JUG 0.8679
1004 HFB 0.8678
1005 1A7 0.8678
1006 8IG 0.8677
1007 G3H 0.8675
1008 5JC 0.8675
1009 MZG 0.8675
1010 G3P 0.8675
1011 5B1 0.8675
1012 H5B 0.8673
1013 5UC 0.8672
1014 6KX 0.8672
1015 271 0.8672
1016 I3E 0.8670
1017 EJZ 0.8670
1018 2D3 0.8670
1019 BK9 0.8669
1020 1QP 0.8669
1021 A2G 0.8668
1022 40E 0.8667
1023 GNM 0.8666
1024 R2B 0.8665
1025 MWJ 0.8664
1026 ES9 0.8661
1027 BM3 0.8661
1028 2A7 0.8659
1029 SLC 0.8657
1030 3QM 0.8656
1031 TEO 0.8655
1032 BCF 0.8651
1033 M5N 0.8651
1034 BPY 0.8649
1035 45L 0.8649
1036 PYD 0.8647
1037 E35 0.8645
1038 RSF 0.8644
1039 8K2 0.8643
1040 FK8 0.8642
1041 ES0 0.8641
1042 MAJ 0.8641
1043 264 0.8640
1044 3CE 0.8639
1045 3V4 0.8639
1046 F9Y 0.8639
1047 1WG 0.8639
1048 FPI 0.8638
1049 7WA 0.8636
1050 RBJ 0.8636
1051 0FK 0.8636
1052 GCO 0.8635
1053 IPM 0.8635
1054 NGA 0.8634
1055 8NY 0.8634
1056 3HP 0.8631
1057 OXQ 0.8628
1058 HPS 0.8627
1059 2YU 0.8626
1060 BBF 0.8625
1061 2CQ 0.8625
1062 4JC 0.8624
1063 MBD 0.8623
1064 2CM 0.8622
1065 4HP 0.8622
1066 GT0 0.8620
1067 BE7 0.8617
1068 MFU 0.8617
1069 2MY 0.8613
1070 TH0 0.8611
1071 6OT 0.8610
1072 DEN 0.8609
1073 2C2 0.8609
1074 GWM 0.8606
1075 H8N 0.8605
1076 DUB 0.8604
1077 JZ9 0.8604
1078 B60 0.8600
1079 2FT 0.8599
1080 X0W 0.8597
1081 E1T 0.8595
1082 A9P 0.8595
1083 7CZ 0.8592
1084 5CL 0.8591
1085 IBF 0.8588
1086 DJN 0.8588
1087 FFP 0.8582
1088 150 0.8581
1089 1XN 0.8580
1090 2BX 0.8578
1091 K8X 0.8574
1092 M1Z 0.8573
1093 JXW 0.8572
1094 MHK 0.8572
1095 4AV 0.8571
1096 K6X 0.8571
1097 EHM 0.8565
1098 YTX 0.8564
1099 ENL 0.8564
1100 KW8 0.8560
1101 PEY 0.8558
1102 FUB 0.8557
1103 ALE 0.8556
1104 CBF 0.8554
1105 A09 0.8552
1106 PCI 0.8550
1107 BZI 0.8542
1108 BZF 0.8541
1109 3MH 0.8540
1110 94N 0.8538
1111 NBG 0.8532
1112 CFA 0.8531
1113 AS3 0.8526
1114 TRA 0.8526
1115 MAQ 0.8521
1116 TLD 0.8520
1117 UQ 0.8514
1118 M6Z 0.8512
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6JZ2; Ligand: SJ5; Similar sites found with APoc: 21
This union binding pocket(no: 1) in the query (biounit: 6jz2.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 6NCZ FYJ 41.0866
2 6NCZ FYJ 41.0866
3 6NCZ FYJ 41.0866
4 6NCZ FYJ 41.0866
5 6NCZ FYJ 41.0866
6 6NCZ FYJ 41.0866
7 6NCZ FYJ 41.0866
8 6NCZ FYJ 41.0866
9 6NCZ FYJ 41.0866
10 6NCZ FYJ 41.0866
11 6NCZ FYJ 41.0866
12 6NCZ FYJ 41.0866
13 6D50 GCB 42.4448
14 6D50 GCB 42.4448
15 6D6W GCU 44.3869
16 6D6W GCU 44.3869
17 6D6W GCU 44.3869
18 6D6W GCU 44.3869
19 6D6W GCU 44.3869
20 6D6W GCU 44.3869
21 6D6W GCU 44.3869
Pocket No.: 2; Query (leader) PDB : 6JZ2; Ligand: SJ5; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 6jz2.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 6JZ2; Ligand: SJ5; Similar sites found with APoc: 21
This union binding pocket(no: 3) in the query (biounit: 6jz2.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 6NCZ FYJ 41.0866
2 6NCZ FYJ 41.0866
3 6NCZ FYJ 41.0866
4 6NCZ FYJ 41.0866
5 6NCZ FYJ 41.0866
6 6NCZ FYJ 41.0866
7 6NCZ FYJ 41.0866
8 6NCZ FYJ 41.0866
9 6NCZ FYJ 41.0866
10 6NCZ FYJ 41.0866
11 6NCZ FYJ 41.0866
12 6NCZ FYJ 41.0866
13 6D50 GCB 42.4448
14 6D50 GCB 42.4448
15 6D6W GCU 44.3869
16 6D6W GCU 44.3869
17 6D6W GCU 44.3869
18 6D6W GCU 44.3869
19 6D6W GCU 44.3869
20 6D6W GCU 44.3869
21 6D6W GCU 44.3869
Pocket No.: 4; Query (leader) PDB : 6JZ2; Ligand: SJ5; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 6jz2.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback