Receptor
PDB id Resolution Class Description Source Keywords
6ORF 1.7 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF SPGH29 STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 (SATCC BAA-334 / TIGR4) GLYCOSIDE HYDROLASE HYDROLASE
Ref.: TWO COMPLEMENTARY ALPHA-FUCOSIDASES FROMSTREPTOCOCC PNEUMONIAEPROMOTE COMPLETE DEGRADATION OF HOST-DERI CARBOHYDRATE ANTIGENS. J.BIOL.CHEM. V. 294 12670 2019
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO A:508;
A:507;
A:504;
B:504;
A:506;
A:505;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
 submit data
62.068 C2 H6 O2 C(CO)...
NDG FUC GAL C:1;
D:1;
 Valid;
Valid;
 none;
none;
 submit data
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6ORH 1.62 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF SPGH29 STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 (SATCC BAA-334 / TIGR4) GLYCOSIDE HYDROLASE HYDROLASE
Ref.: TWO COMPLEMENTARY ALPHA-FUCOSIDASES FROMSTREPTOCOCC PNEUMONIAEPROMOTE COMPLETE DEGRADATION OF HOST-DERI CARBOHYDRATE ANTIGENS. J.BIOL.CHEM. V. 294 12670 2019
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 312 families.
1 6OR4 - NAG GAL FUC n/a n/a
2 6ORH - NDG FUC GAL FUC n/a n/a
3 6ORF - NDG FUC GAL n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 261 families.
1 6OR4 - NAG GAL FUC n/a n/a
2 6ORH - NDG FUC GAL FUC n/a n/a
3 6ORF - NDG FUC GAL n/a n/a
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 214 families.
1 4OUE - IPT C9 H18 O5 S CC(C)S[C@H....
2 6OR4 - NAG GAL FUC n/a n/a
3 6ORH - NDG FUC GAL FUC n/a n/a
4 6ORF - NDG FUC GAL n/a n/a
5 6TR4 - FUC C6 H12 O5 C[C@H]1[C@....
6 6TR3 - FUL C6 H12 O5 C[C@H]1[C@....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: NDG FUC GAL; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: NDG FUC GAL; Similar ligands found: 9
No: Ligand Similarity coefficient
1 NDG FUC GAL 1.0000
2 NAG FUC GAL 0.9753
3 MAG FUC GAL 0.9323
4 NAG GAL FUC 0.9217
5 BGC FUC GAL 0.9021
6 NDG GAL FUC 0.8928
7 MAG FUC SGA 0.8868
8 NAG FUC SGA 0.8867
9 MAG FUC G4S 0.8810
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6ORH; Ligand: NDG FUC GAL FUC; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6orh.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 6ORH; Ligand: NDG FUC GAL FUC; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 6orh.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
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