Receptor
PDB id Resolution Class Description Source Keywords
6ar2 1.55 Å NON-ENZYME: OTHER STRUCTURE OF HUMAN SLMAP FHA DOMAIN IN COMPLEX WITH PMST2 HOMO SAPIENS HIPPO SLMAP FHA PHOSPHO-MST2 MEMBRANE PROTEIN
Ref.: SAV1 PROMOTES HIPPO KINASE ACTIVATION THROUGH ANTAG THE PP2A PHOSPHATASE STRIPAK. ELIFE V. 6 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GLU GLU GLU ASP GLY TPO MET LYS ARG ASN C:376;
D:376;
 Valid;
Valid;
 Atoms found LESS than expected: % Diff = 0.414;
Atoms found LESS than expected: % Diff = 0.414;
 submit data
769.795 n/a S(CCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6AR2 1.55 Å NON-ENZYME: OTHER STRUCTURE OF HUMAN SLMAP FHA DOMAIN IN COMPLEX WITH PMST2 HOMO SAPIENS HIPPO SLMAP FHA PHOSPHO-MST2 MEMBRANE PROTEIN
Ref.: SAV1 PROMOTES HIPPO KINASE ACTIVATION THROUGH ANTAG THE PP2A PHOSPHATASE STRIPAK. ELIFE V. 6 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 6AR2 - GLU GLU GLU ASP GLY TPO MET LYS ARG ASN n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 6AR2 - GLU GLU GLU ASP GLY TPO MET LYS ARG ASN n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6AR2 - GLU GLU GLU ASP GLY TPO MET LYS ARG ASN n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GLU GLU GLU ASP GLY TPO MET LYS ARG ASN; Similar ligands found: 18
No: Ligand ECFP6 Tc MDL keys Tc
1 GLU GLU GLU ASP GLY TPO MET LYS ARG ASN 1 1
2 ALA ARG TPO LYS 0.454545 0.887097
3 LYS ARG LYS ARG LYS ARG LYS ARG LYS ARG 0.452174 0.66129
4 ALA ARG VAL SER MET ARG ARG MET SEP ASN 0.430769 0.876923
5 ALA ARG LYS SEP THR GLY GLY LYS 0.429577 0.861538
6 GLY ASP GLU VAL LYS VAL PHE ARG 0.424658 0.712121
7 ILE LYS ARG SER LYS LYS ASN SER LEU ALA 0.420168 0.676923
8 LEU GLY GLY ALA LYS GLN ARG GLY ASP VAL 0.41791 0.746032
9 VAL ARG MET 0.417391 0.698413
10 ARG HIS LYS ALY LEU MET PHE LYS 0.410256 0.626667
11 GLN ILE LYS VAL ARG VAL ASP MET VAL 0.409722 0.796875
12 ALA ARG THR LYS GLN THR ALA ARG 0.409449 0.734375
13 THR ARG SER GLY ALY VAL MET ARG ARG LEU 0.408759 0.78125
14 GLU LEU LYS TPO GLU ARG TYR 0.407895 0.814286
15 GLU ALY ARG 0.406504 0.714286
16 ALA ARG THR LYS GLN THR ALA ARG LYS 0.404412 0.75
17 GLU LEU ARG ARG LYS MET MET TYR MET 0.40411 0.742857
18 LYS GLY GLY ALA ALY ARG HIS ARG LYS ILE 0.4 0.638889
Similar Ligands (3D)
Ligand no: 1; Ligand: GLU GLU GLU ASP GLY TPO MET LYS ARG ASN; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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