Receptor
PDB id Resolution Class Description Source Keywords
7RNT 1.9 Å EC: 3.1.27.3 CRYSTAL STRUCTURE OF THE TYR45TRP MUTANT OF RIBONUCLEASE T1 IN A COMPLEX WITH 2'-ADENYLIC ACID ASPERGILLUS ORYZAE HYDROLASE(ENDORIBONUCLEASE)
Ref.: CRYSTAL STRUCTURE OF THE TYR45TRP MUTANT OF RIBONUCLEASE T1 IN A COMPLEX WITH 2'-ADENYLIC ACID. EUR.J.BIOCHEM. V. 201 199 1991
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
2AM A:105;
Valid;
none;
submit data
347.221 C10 H14 N5 O7 P c1nc(...
CA A:106;
Part of Protein;
none;
submit data
40.078 Ca [Ca+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1RNT 1.9 Å EC: 3.1.27.3 RESTRAINED LEAST-SQUARES REFINEMENT OF THE CRYSTAL STRUCTURE OF THE RIBONUCLEASE T1(ASTERISK)2(PRIME)- G UANYLIC ACID COMPLEX AT 1.9 ANGSTROMS RESOLUTION ASPERGILLUS ORYZAE HYDROLASE(ENDORIBONUCLEASE)
Ref.: RESTRAINED LEAST-SQUARES REFINEMENT OF THE CRYSTAL STRUCTURE OF THE RIBONUCLEASE T1(ASTERISK)2(PRIME)-GUANYLIC ACID COMPLEX AT 1.9 ANGSTROMS RESOLUTION ACTA CRYSTALLOGR.,SECT.B V. 43 548 1987
Members (54)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 6GSP - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
2 1TRP - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
3 5GSP - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
4 7RNT - 2AM C10 H14 N5 O7 P c1nc(c2c(n....
5 1FYS - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
6 1LOV - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
7 6RNT Kd = 4.3 mM 2AM C10 H14 N5 O7 P c1nc(c2c(n....
8 1RGA - G C10 H14 N5 O8 P c1nc2c(n1[....
9 1RLS - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
10 1LOW - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
11 1I2F - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
12 1DET Kd = 50 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
13 1HZ1 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
14 5BIR Kd = 255 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
15 1FZU - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
16 1B2M - G U34 n/a n/a
17 1BVI - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
18 1I2E - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
19 1G02 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
20 1BIR Kd = 138 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
21 1RNT Kd = 6.5 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
22 3BIR Kd = 112 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
23 1CH0 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
24 1I3I - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
25 4GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
26 2AAD - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
27 5HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
28 3BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
29 3SYU Kd = 50 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
30 1I0V - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
31 1RHL - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
32 1I2G - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
33 1I0X - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
34 1RGK Kd = 49 uM 2AM C10 H14 N5 O7 P c1nc(c2c(n....
35 1I3F - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
36 1LRA - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
37 4HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
38 2RNT - GPG C20 H25 N10 O12 P c1nc2c(n1[....
39 2BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
40 5BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
41 2BIR - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
42 1RGC - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
43 1GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
44 2HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
45 1HYF - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
46 7GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
47 3GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
48 3HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
49 1LOY - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
50 1BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
51 2GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
52 1RGL Kd = 37 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
53 1TRQ - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
54 4BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
70% Homology Family (57)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6GSP - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
2 1TRP - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
3 5GSP - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
4 7RNT - 2AM C10 H14 N5 O7 P c1nc(c2c(n....
5 1FYS - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
6 1LOV - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
7 6RNT Kd = 4.3 mM 2AM C10 H14 N5 O7 P c1nc(c2c(n....
8 1RGA - G C10 H14 N5 O8 P c1nc2c(n1[....
9 1RLS - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
10 1LOW - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
11 1I2F - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
12 1DET Kd = 50 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
13 1HZ1 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
14 5BIR Kd = 255 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
15 1FZU - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
16 1B2M - G U34 n/a n/a
17 1BVI - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
18 1I2E - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
19 1G02 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
20 1BIR Kd = 138 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
21 1RNT Kd = 6.5 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
22 3BIR Kd = 112 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
23 1CH0 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
24 1I3I - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
25 4GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
26 2AAD - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
27 5HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
28 3BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
29 3SYU Kd = 50 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
30 1I0V - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
31 1RHL - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
32 1I2G - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
33 1I0X - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
34 1RGK Kd = 49 uM 2AM C10 H14 N5 O7 P c1nc(c2c(n....
35 1I3F - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
36 1LRA - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
37 4HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
38 2RNT - GPG C20 H25 N10 O12 P c1nc2c(n1[....
39 2BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
40 5BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
41 2BIR - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
42 1RGC - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
43 1GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
44 2HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
45 1HYF - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
46 7GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
47 3GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
48 3HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
49 1LOY - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
50 1BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
51 2GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
52 1RGL Kd = 37 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
53 1TRQ - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
54 4BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
55 1RMS - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
56 1RDS - GPC C19 H24 F N8 O11 P c1nc2c(n1[....
57 1FUT - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
50% Homology Family (60)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6GSP - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
2 1TRP - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
3 5GSP - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
4 7RNT - 2AM C10 H14 N5 O7 P c1nc(c2c(n....
5 1FYS - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
6 1LOV - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
7 6RNT Kd = 4.3 mM 2AM C10 H14 N5 O7 P c1nc(c2c(n....
8 1RGA - G C10 H14 N5 O8 P c1nc2c(n1[....
9 1RLS - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
10 1LOW - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
11 1I2F - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
12 1DET Kd = 50 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
13 1HZ1 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
14 5BIR Kd = 255 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
15 1FZU - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
16 1B2M - G U34 n/a n/a
17 1BVI - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
18 1I2E - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
19 1G02 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
20 1BIR Kd = 138 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
21 1RNT Kd = 6.5 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
22 3BIR Kd = 112 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
23 1CH0 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
24 1I3I - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
25 4GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
26 2AAD - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
27 5HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
28 3BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
29 3SYU Kd = 50 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
30 1I0V - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
31 1RHL - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
32 1I2G - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
33 1I0X - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
34 1RGK Kd = 49 uM 2AM C10 H14 N5 O7 P c1nc(c2c(n....
35 1I3F - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
36 1LRA - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
37 4HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
38 2RNT - GPG C20 H25 N10 O12 P c1nc2c(n1[....
39 2BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
40 5BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
41 2BIR - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
42 1RGC - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
43 1GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
44 2HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
45 1HYF - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
46 7GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
47 3GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
48 3HOH - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
49 1LOY - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
50 1BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
51 2GSP - SGP C10 H12 N5 O6 P S c1nc2c(n1[....
52 1RGL Kd = 37 uM 2GP C10 H14 N5 O8 P c1nc2c(n1[....
53 1TRQ - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
54 4BU4 - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
55 1RMS - 3GP C10 H14 N5 O8 P c1nc2c(n1[....
56 1RDS - GPC C19 H24 F N8 O11 P c1nc2c(n1[....
57 3AGO - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
58 3AHW - 2AM C10 H14 N5 O7 P c1nc(c2c(n....
59 3AGN - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
60 1FUT - 2GP C10 H14 N5 O8 P c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 2AM; Similar ligands found: 237
No: Ligand ECFP6 Tc MDL keys Tc
1 2AM 1 1
2 OVE 0.828125 0.957747
3 A2P 0.80597 0.956522
4 ATR 0.739726 0.971014
5 3AM 0.691176 0.956522
6 A2R 0.683544 0.930556
7 A22 0.675 0.930556
8 NA7 0.642857 0.905405
9 A3P 0.635135 0.942857
10 ADN 0.6 0.842857
11 RAB 0.6 0.842857
12 XYA 0.6 0.842857
13 7D5 0.591549 0.902778
14 AMP 0.589041 0.942857
15 A 0.589041 0.942857
16 25A 0.588235 0.916667
17 PAP 0.5875 0.957143
18 V3L 0.573171 0.916667
19 PPS 0.566265 0.848101
20 7D7 0.560606 0.763889
21 25L 0.549451 0.930556
22 ABM 0.545455 0.890411
23 A2D 0.545455 0.916667
24 ADP 0.544304 0.943662
25 101 0.539474 0.902778
26 SRA 0.539474 0.891892
27 7D3 0.538462 0.90411
28 AN2 0.5375 0.930556
29 2A5 0.536585 0.917808
30 5N5 0.536232 0.816901
31 PO4 PO4 A A A A PO4 0.533333 0.901408
32 AMP MG 0.532468 0.864865
33 AP2 0.531646 0.905405
34 A12 0.531646 0.905405
35 BA3 0.531646 0.916667
36 SAP 0.53012 0.893333
37 AGS 0.53012 0.893333
38 NDP 0.529412 0.87013
39 NPW 0.529412 0.8375
40 5CD 0.528571 0.777778
41 A4D 0.528571 0.816901
42 B4P 0.525 0.916667
43 AP5 0.525 0.916667
44 ATP 0.52439 0.943662
45 TXP 0.524272 0.87013
46 NZQ 0.524272 0.858974
47 ODP 0.519231 0.858974
48 NJP 0.519231 0.893333
49 SON 0.518519 0.88
50 5FA 0.518072 0.943662
51 AQP 0.518072 0.943662
52 APC 0.518072 0.905405
53 XNP 0.514286 0.848101
54 7D4 0.512195 0.90411
55 CA0 0.512195 0.891892
56 ADX 0.512195 0.825
57 M33 0.512195 0.90411
58 AU1 0.512195 0.917808
59 EP4 0.506849 0.727273
60 ACP 0.506024 0.917808
61 50T 0.506024 0.930556
62 AR6 0.5 0.916667
63 TAT 0.5 0.905405
64 M2T 0.5 0.708861
65 ACQ 0.5 0.917808
66 APR 0.5 0.916667
67 5AD 0.5 0.742857
68 PRX 0.5 0.866667
69 DTA 0.5 0.76
70 ADQ 0.494505 0.917808
71 ADV 0.494118 0.88
72 RBY 0.494118 0.88
73 AD9 0.494118 0.917808
74 ADP MG 0.493976 0.853333
75 A3G 0.493671 0.797297
76 MTA 0.493333 0.746667
77 Y3J 0.492958 0.722222
78 ATF 0.488636 0.905405
79 AV2 0.488636 0.916667
80 2VA 0.488095 0.797297
81 ADP BEF 0.488095 0.831169
82 BEF ADP 0.488095 0.831169
83 2GP 0.487805 0.905405
84 103 0.487179 0.835616
85 ACK 0.487179 0.913043
86 QQY 0.487179 0.863014
87 3AD 0.486111 0.828571
88 OAD 0.483871 0.891892
89 ANP 0.482759 0.917808
90 6RE 0.481013 0.75641
91 3DH 0.480519 0.746667
92 NAP 0.477876 0.891892
93 5AL 0.477273 0.878378
94 ADP PO3 0.476744 0.888889
95 DA 0.475 0.902778
96 D5M 0.475 0.902778
97 NEC 0.475 0.767123
98 AOC 0.475 0.794521
99 QQX 0.474359 0.851351
100 1DG 0.473684 0.87013
101 TAP 0.473684 0.857143
102 DG1 0.473684 0.87013
103 CC5 0.471429 0.788732
104 SO8 0.471264 0.786667
105 VRT 0.471264 0.766234
106 ATP MG 0.471264 0.853333
107 5X8 0.470588 0.736842
108 5AS 0.46988 0.755814
109 NA0 0.469565 0.88
110 ZAS 0.468354 0.74026
111 ADP BMA 0.468085 0.891892
112 5SV 0.467391 0.822785
113 SRP 0.466667 0.88
114 GAP 0.465909 0.866667
115 3AT 0.465909 0.943662
116 3L1 0.465753 0.794521
117 3D1 0.465753 0.794521
118 A3S 0.464286 0.808219
119 S4M 0.463415 0.662791
120 NVA 2AD 0.45977 0.786667
121 MAO 0.457831 0.73494
122 00A 0.457447 0.833333
123 DSH 0.45679 0.721519
124 MAP 0.456522 0.893333
125 ALF ADP 0.455556 0.820513
126 ADP ALF 0.455556 0.820513
127 DAT 0.453488 0.90411
128 SFG 0.453488 0.723684
129 A3T 0.453488 0.819444
130 APU 0.45283 0.893333
131 A A A 0.452632 0.853333
132 OOB 0.451613 0.878378
133 8QN 0.451613 0.878378
134 J7C 0.451219 0.766234
135 A3N 0.451219 0.783784
136 ANP MG 0.450549 0.844156
137 VO4 ADP 0.450549 0.878378
138 ADP VO4 0.450549 0.878378
139 A A 0.447917 0.916667
140 PR8 0.447917 0.825
141 A1R 0.446809 0.881579
142 4AD 0.446809 0.868421
143 AMO 0.446809 0.88
144 PAJ 0.446809 0.858974
145 GJV 0.445783 0.746835
146 0WD 0.445455 0.87013
147 NMN AMP PO4 0.445455 0.820513
148 UPA 0.443396 0.881579
149 PTJ 0.443299 0.846154
150 1ZZ 0.443299 0.792683
151 3OD 0.443299 0.891892
152 BIS 0.443299 0.881579
153 FYA 0.443299 0.878378
154 A5D 0.443182 0.76
155 SA8 0.443182 0.682927
156 DLL 0.442105 0.878378
157 AHX 0.442105 0.87013
158 AR6 AR6 0.441176 0.864865
159 DAL AMP 0.44086 0.853333
160 GGZ 0.44086 0.822785
161 CO7 0.439024 0.781609
162 TM1 0.438776 0.771084
163 SAH 0.438202 0.717949
164 SAI 0.438202 0.708861
165 G5A 0.438202 0.755814
166 3UK 0.4375 0.866667
167 S7M 0.434783 0.666667
168 SMM 0.434783 0.662791
169 9SN 0.434343 0.822785
170 5F1 0.434211 0.72973
171 OMR 0.433962 0.804878
172 AS 0.433735 0.855263
173 DTP 0.433333 0.90411
174 LAD 0.43299 0.835443
175 WAQ 0.43299 0.833333
176 SP1 0.432099 0.84
177 RP1 0.432099 0.84
178 A7D 0.430233 0.773333
179 ATP A A A 0.43 0.876712
180 NB8 0.428571 0.846154
181 TXA 0.428571 0.88
182 EEM 0.428571 0.666667
183 JB6 0.428571 0.833333
184 ME8 0.428571 0.792683
185 TSB 0.425532 0.77381
186 MHZ 0.425287 0.694118
187 MYR AMP 0.424242 0.771084
188 A5A 0.423913 0.761905
189 2BA 0.423529 0.887324
190 CMP 0.423529 0.9
191 ENP 0.42268 0.866667
192 ARJ 0.421053 0.746479
193 N01 0.421053 0.853333
194 GEK 0.421053 0.691358
195 SSA 0.419355 0.776471
196 NOC 0.418919 0.760563
197 P5A 0.418367 0.722222
198 SAM 0.417582 0.666667
199 DDS 0.417582 0.876712
200 YAP 0.415842 0.844156
201 FA5 0.415842 0.855263
202 52H 0.414894 0.735632
203 54H 0.414894 0.744186
204 VMS 0.414894 0.744186
205 AFH 0.413462 0.858974
206 ANZ 0.413462 0.820513
207 AAT 0.413043 0.703704
208 A U 0.412844 0.844156
209 XAH 0.411765 0.814815
210 NAI 0.411215 0.857143
211 ZDA 0.411111 0.837838
212 53H 0.410526 0.735632
213 5CA 0.410526 0.776471
214 D3Y 0.410526 0.786667
215 5J9 0.41 0.728395
216 K15 0.408163 0.658824
217 A6D 0.408163 0.698795
218 4UV 0.407767 0.844156
219 V1N 0.407767 0.890411
220 LAQ 0.40566 0.792683
221 ETB 0.405172 0.809524
222 DCA 0.405172 0.8
223 3NZ 0.40404 0.779221
224 G3A 0.403846 0.87013
225 AP0 0.40367 0.846154
226 5HG 0.402597 0.723684
227 AFX 0.402597 0.675325
228 NSS 0.402062 0.755814
229 0UM 0.402062 0.695122
230 LSS 0.402062 0.719101
231 DSZ 0.402062 0.755814
232 48N 0.401869 0.846154
233 PUA 0.401709 0.858974
234 7MD 0.4 0.8375
235 4UU 0.4 0.844156
236 G5P 0.4 0.87013
237 0XU 0.4 0.701299
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1RNT; Ligand: 2GP; Similar sites found: 13
This union binding pocket(no: 1) in the query (biounit: 1rnt.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4V03 ADP 0.006933 0.41123 None
2 4DXJ 0M9 0.01321 0.40199 None
3 4DXJ IPE 0.01603 0.40064 None
4 3LQV ADE 0.005034 0.44133 3.84615
5 2XK9 XK9 0.0158 0.40434 4.80769
6 2X4Z X4Z 0.01621 0.40271 7.69231
7 3ZS9 ADP ALF 0.00919 0.40193 7.69231
8 4GYI ADP 0.008829 0.41032 8.65385
9 5LNE A2G GAL 0.01464 0.40928 9.61539
10 3DGY 2GP 0.000001197 0.62686 10.3093
11 4AXD ANP 0.01309 0.41024 10.5769
12 4N70 2HX 0.01939 0.41048 11.5385
13 3BFV ADP 0.01469 0.40377 26.9231
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