 
PDB ID
|
Resolution
|
Source
|
Class
|
Ligands
|
Binding Data
|
Molecular Weight (Da)
|
|---|---|---|---|---|---|---|
| 1IIH | 2.2 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | 3PG | Ki = 1.3 mM | 186.057 |
| 1KV5 | 1.65 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | SO4, PGA, GOL, DTT | Ki = 60 uM | 96.063, 156.031, 92.094, 154.251 |
| 1TRD | 2.5 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | PGH | Ki = 4 uM | 171.046 |
| 1TTI | 2.4 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | PGA | 156.031 | |
| 1TTJ | 2.4 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | PGH | 171.046 | |
| 2C7V | 2.2 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NI, NAP, MTX, ACT | Ki = 152 nM | 58.693, 743.405, 454.439, 59.044 |
| 2J27 | 1.15 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | SO4, PGA | Ki = 0.3 mM | 96.063, 156.031 |
| 2O2C | 1.58 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.9 | GOL, G6Q | 92.094, 260.136 | |
| 2O2D | 1.9 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.9 | GOL, CIT | 92.094, 192.124 | |
| 2V2C | 1.89 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | SO4, PGA | Ki = 0.39 mM | 96.063, 156.031 |
| 2V2H | 1.18 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | PGA, CL | Ki = 0.17 mM | 156.031, 35.453 |
| 2VEK | 1.6 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | TBU, CIT, ASF | 74.122, 192.124, 194.249 | |
| 2VEL | 2.3 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | PGA, CL | 156.031, 35.453 | |
| 2VEN | 2 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | CIT | 192.124 | |
| 2VZ0 | 1.9 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, D64 | Ki = 9.8 nM | 743.405, 250.298 |
| 2WBA | 2.3 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.8.1.12 | SO4, PG4, NDP, GOL, FAD | 96.063, 194.226, 745.421, 92.094, 785.55 | |
| 2WD7 | 1.9 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, VGD | Ki = 10.6 uM | 743.405, 167.596 |
| 2WD8 | 2.1 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | CL, VGF, NAP | Kd = 10.6 uM | 35.453, 368.259, 743.405 |
| 2X1R | 1.98 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | X1R, SO4 | 180.222, 96.063 | |
| 2X1S | 1.93 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | X1S, SO4 | 154.142, 96.063 | |
| 2X1T | 1.83 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | RES | 231.098 | |
| 2X2G | 1.9 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 5.3.1.1 | 3PG | 186.057 | |
| 2X9G | 1.1 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, LYA, ACT | Ki ~ 30 nM | 743.405, 427.411, 59.044 |
| 2X9N | 1.15 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, NA, DTD, D1D, AX3, ACT | Ki > 0.035 mM | 743.405, 22.99, 152.235, 152.235, 166.184, 59.044 |
| 2X9V | 1.3 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | TMQ, NAP, ACT | Ki ~ 70 nM | 370.426, 743.405, 59.044 |
| 3BMN | 1.98 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, GOL, EDO, AX3, ACT | Ki > 35 uM | 743.405, 92.094, 62.068, 166.184, 59.044 |
| 3BMO | 1.6 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, NA, GOL, DTT, ACT, D1D, AX4 | Ki = 5.4 uM | 743.405, 22.99, 92.094, 154.251, 59.044, 152.235, 232.305 |
| 3BMQ | 1.7 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, GOL, DTT, AX5, ACT | Ki = 3.2 uM | 743.405, 92.094, 154.251, 232.305, 59.044 |
| 3GN1 | 2 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, AX7, ACT | Ki = 288 uM | 743.405, 133.151, 59.044 |
| 3GN2 | 1.6 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, AX8, ACT | Ki = 0.4 uM | 743.405, 292.163, 59.044 |
| 3MCV | 1.7 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, MCV, ACT | Ki = 70 nM | 743.405, 330.405, 59.044 |
| 3W54 | 2.3 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME OXIDOREDUCTASES | GOL, RNB, SO4, FE, OH | ic50 = 0.2 nM | 92.094, 322.826, 96.063, 55.845, 17.007 |
| 4CL8 | 2.2 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, ACT, OZJ | 743.405, 59.044, 278.269 | |
| 4CLD | 1.77 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, JUO, ACT | Ki = 8.8 uM | 743.405, 260.318, 59.044 |
| 4CLE | 1.8 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, DTD, JR2 | Ki = 4.2 uM | 743.405, 152.235, 203.244 |
| 4CLH | 1.85 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | ACT, NAP, W8G | Ki = 8.6 uM | 59.044, 743.405, 235.309 |
| 4CLO | 1.88 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | GOL, NAP, XP0 | Ki = 0.19 uM | 92.094, 743.405, 303.361 |
| 4CLR | 1.75 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, FDB | Ki = 7.3 uM | 743.405, 164.165 |
| 4CLX | 1.85 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, Q0K, ACT | Ki = 1.2 uM | 743.405, 240.261, 59.044 |
| 4CM1 | 1.9 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | ACT, IQW, NAP, DTT | Ki = 0.32 uM | 59.044, 239.276, 743.405, 154.251 |
| 4CM3 | 1.95 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | DTU, NAP, ACT, KP2 | Ki = 0.4 uM | 154.251, 743.405, 59.044, 225.249 |
| 4CM4 | 1.81 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | GOL, NAP, ACT, 4NR | Ki = 0.48 uM | 92.094, 743.405, 59.044, 243.24 |
| 4CM5 | 1.99 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, NWJ | 743.405, 332.359 | |
| 4CM6 | 1.7 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, ACT, AOB | Ki = 0.137 uM | 743.405, 59.044, 277.281 |
| 4CM7 | 1.9 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | H0V, NAP, ACT | Ki = 0.26 uM | 253.302, 743.405, 59.044 |
| 4CM8 | 1.9 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | GOL, NAP, IZ9, ACT, DTT | Ki = 0.35 uM | 92.094, 743.405, 290.323, 59.044, 154.251 |
| 4CM9 | 1.9 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | ACT, DTT, NAP, YGL | Ki = 1.17 uM | 59.044, 154.251, 743.405, 302.33 |
| 4CMA | 1.85 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | M2N, NAP, ACT | Ki = 0.59 uM | 301.345, 743.405, 59.044 |
| 4CMB | 1.96 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, ACT, UEN | Ki = 0.56 uM | 743.405, 59.044, 325.383 |
| 4CMC | 1.85 | TRYPANOSOMA BRUCEI BRUCEI | ENZYME 1.5.1.33 | NAP, VS8 | Ki = 0.2 uM | 743.405, 383.489 |
