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Receptor

PDB id	Resolution	Class	Description	Source	Keywords
1LW4	1.9 Å	EC: 4.1.2.5	X-RAY STRUCTURE OF L-THREONINE ALDOLASE (LOW-SPECIFICITY) IN WITH L-ALLO-THREONINE	THERMOTOGA MARITIMA	PYRIDOXAL-5-PHOSPHATE PLP ENZYME PRODUCT COMPLEX THREONISTRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIATIVE NEWRESEARCH CENTER FOR STRUCTURAL GENOMICS NYSGXRC LYASE
Ref.:	X-RAY STRUCTURES OF THREONINE ALDOLASE COMPLEXES: S BASIS OF SUBSTRATE RECOGNITION BIOCHEMISTRY V. 41 11711 2002

Ligand

Ligand	Chain:Residue	Validity	Ligand Warnings	Binding Data	Molecular Weight (Da)	Formula	SMILES
CA	A:1056; B:1054; B:1057; B:1058; D:1055; D:1059;	Part of Protein; Part of Protein; Part of Protein; Part of Protein; Part of Protein; Part of Protein;	none; none; none; none; none; none;	submit data	40.078	Ca	[Ca+2...
CL	A:1060; A:1064; B:1063; B:1065; C:1061; D:1062;	Invalid; Invalid; Invalid; Invalid; Invalid; Invalid;	none; none; none; none; none; none;	submit data	35.453	Cl	[Cl-]
PLP	B:1053;	Valid;	none;	submit data	247.142	C8 H10 N O6 P	Cc1c(...
TLP	B:1050; C:1051; D:1052;	Valid; Valid; Valid;	none; none; none;	submit data	350.262	C12 H19 N2 O8 P	Cc1c(...

View in 3D viewer

90% Homology Family

Leader

PDB id	Resolution	Class	Description	Source	Keywords
1LW4	1.9 Å	EC: 4.1.2.5	X-RAY STRUCTURE OF L-THREONINE ALDOLASE (LOW-SPECIFICITY) IN WITH L-ALLO-THREONINE	THERMOTOGA MARITIMA	PYRIDOXAL-5-PHOSPHATE PLP ENZYME PRODUCT COMPLEX THREONISTRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIATIVE NEWRESEARCH CENTER FOR STRUCTURAL GENOMICS NYSGXRC LYASE
Ref.:	X-RAY STRUCTURES OF THREONINE ALDOLASE COMPLEXES: S BASIS OF SUBSTRATE RECOGNITION BIOCHEMISTRY V. 41 11711 2002

Members (2)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 2 families.
1	1LW5	-	PLG	C10 H15 N2 O7 P	Cc1c(c(c(c....
2	1LW4	-	PLP	C8 H10 N O6 P	Cc1c(c(c(c....

70% Homology Family (2)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 2 families.
1	1LW5	-	PLG	C10 H15 N2 O7 P	Cc1c(c(c(c....
2	1LW4	-	PLP	C8 H10 N O6 P	Cc1c(c(c(c....

50% Homology Family (4)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 1 families.
1	1LW5	-	PLG	C10 H15 N2 O7 P	Cc1c(c(c(c....
2	1LW4	-	PLP	C8 H10 N O6 P	Cc1c(c(c(c....
3	3WGC	-	PLG	C10 H15 N2 O7 P	Cc1c(c(c(c....
4	4LNL	-	PLG	C10 H15 N2 O7 P	Cc1c(c(c(c....

Polypharmacology

Similar Ligands (2D)

Ligand no: 1; Ligand: PLP; Similar ligands found: 71

No:	Ligand	ECFP6 Tc	MDL keys Tc
1	PLP	1	1
2	PZP	0.729167	0.843137
3	EXT	0.62069	0.8
4	EPC	0.603448	0.862745
5	AN7	0.603448	0.918367
6	FOO	0.59322	0.849057
7	PLR	0.58	0.895833
8	0JO	0.57377	0.803571
9	4LM	0.57377	0.818182
10	P3D	0.571429	0.704918
11	F0G	0.564516	0.865385
12	MPM	0.564516	0.814815
13	KOU	0.555556	0.836364
14	FEV	0.555556	0.803571
15	EVM	0.546875	0.821429
16	HCP	0.546875	0.77193
17	6DF	0.545455	0.811321
18	PXL	0.541667	0.659574
19	Z98	0.537313	0.75
20	PXP	0.537037	0.862745
21	PMP	0.527273	0.767857
22	P0P	0.527273	0.916667
23	PL6	0.522388	0.818182
24	GT1	0.517857	0.830189
25	FEJ	0.514706	0.851852
26	PFM	0.514706	0.803571
27	L7N	0.507246	0.647887
28	P70	0.5	0.833333
29	PL5	0.479452	0.775862
30	PUS	0.479452	0.707692
31	MPL	0.473684	0.836364
32	IN5	0.46875	0.758621
33	PLG	0.46875	0.75
34	P89	0.466667	0.714286
35	PLP PUT	0.463768	0.672131
36	5DK	0.460526	0.725806
37	EQJ	0.460526	0.725806
38	LUH	0.460526	0.686567
39	LUK	0.460526	0.686567
40	O1G	0.454545	0.75
41	PLP ABU	0.450704	0.706897
42	Q0P	0.45	0.762712
43	GLY PLP	0.447761	0.745455
44	PLT	0.439024	0.762712
45	X04	0.431034	0.851852
46	P1T	0.426471	0.714286
47	PDD	0.426471	0.762712
48	PP3	0.426471	0.762712
49	PDA	0.426471	0.762712
50	SER PLP	0.422535	0.781818
51	33P	0.42029	0.745763
52	IK2	0.42029	0.714286
53	CKT	0.42029	0.762712
54	PLP ALO	0.416667	0.796296
55	PLS	0.414286	0.779661
56	2BO	0.414286	0.793103
57	TLP	0.414286	0.793103
58	2BK	0.414286	0.793103
59	5PA	0.414286	0.714286
60	PMH	0.414286	0.619718
61	9TD	0.413793	0.671642
62	PLP 999	0.410959	0.796296
63	C6P	0.408451	0.75
64	PPD	0.408451	0.75
65	QLP	0.405405	0.681818
66	MP5	0.403509	0.666667
67	PLA	0.402778	0.703125
68	PY5	0.402778	0.703125
69	OJQ	0.402778	0.60274
70	PLP PHE	0.4	0.732143
71	HEY	0.4	0.703125

Ligand no: 2; Ligand: TLP; Similar ligands found: 79

No:	Ligand	ECFP6 Tc	MDL keys Tc
1	TLP	1	1
2	2BO	1	1
3	2BK	1	1
4	ILP	0.791045	0.934426
5	PDD	0.753846	0.966102
6	PP3	0.753846	0.966102
7	PDA	0.753846	0.966102
8	PLS	0.705882	0.95
9	C6P	0.695652	0.918033
10	PPD	0.695652	0.918033
11	PY5	0.685714	0.890625
12	IN5	0.681818	0.932203
13	PGU	0.666667	0.888889
14	PDG	0.666667	0.888889
15	7XF	0.666667	0.888889
16	ORX	0.662162	0.875
17	N5F	0.662162	0.875
18	LPI	0.657534	0.850746
19	QLP	0.657534	0.835821
20	PE1	0.653333	0.875
21	PY6	0.648649	0.863636
22	PLG	0.632353	0.918033
23	76U	0.626667	0.846154
24	CBA	0.621622	0.919355
25	33P	0.619718	0.885246
26	0PR	0.615385	0.903226
27	PL4	0.615385	0.875
28	P1T	0.605634	0.875
29	KAM	0.6	0.875
30	IK2	0.597222	0.846154
31	5PA	0.589041	0.875
32	EA5	0.576923	0.848485
33	PLA	0.573333	0.890625
34	AQ3	0.571429	0.861538
35	HEY	0.564103	0.861538
36	3LM	0.556962	0.863636
37	PMP	0.553846	0.881356
38	PMG	0.551282	0.863636
39	GT1	0.545455	0.786885
40	PXP	0.538462	0.844828
41	PSZ	0.5375	0.820895
42	PMH	0.526316	0.739726
43	RW2	0.518072	0.820895
44	PXG	0.518072	0.887097
45	PL2	0.5125	0.753623
46	DCS	0.5125	0.756757
47	7TS	0.5	0.746667
48	DN9	0.5	0.814286
49	CKT	0.493506	0.870968
50	9YM	0.47619	0.830769
51	PLP 2KZ	0.4625	0.854839
52	F0G	0.461538	0.816667
53	PL8	0.45977	0.753425
54	PLR	0.454545	0.745763
55	7B9	0.449438	0.785714
56	FEJ	0.445783	0.836066
57	PPG	0.443182	0.818182
58	P0P	0.442857	0.793103
59	OJQ	0.439024	0.72
60	KOU	0.4375	0.852459
61	PLP PMP	0.43662	0.833333
62	0JO	0.43038	0.738462
63	RMT	0.422222	0.787879
64	PLP 2TL	0.421687	0.933333
65	CAN PLP	0.420455	0.794118
66	PUS	0.420455	0.708333
67	1D0	0.419355	0.848485
68	PL6	0.416667	0.75
69	EVM	0.414634	0.83871
70	PLP	0.414286	0.793103
71	4LM	0.4125	0.777778
72	Z98	0.411765	0.8
73	AN7	0.410256	0.766667
74	EPC	0.410256	0.783333
75	PZP	0.408451	0.766667
76	PLP SER	0.407407	0.885246
77	LCS	0.406977	0.697368
78	FOO	0.405063	0.803279
79	FEV	0.402439	0.765625

Similar Ligands (3D)

Ligand no: 1; Ligand: PLP; Similar ligands found: 1073

No:	Ligand	Similarity coefficient
1	PLP PMP	0.9961
2	1QV	0.9694
3	NPL	0.9683
4	G6P	0.9654
5	BG6	0.9649
6	3LJ	0.9631
7	4R1	0.9560
8	GLP	0.9545
9	BGP	0.9523
10	A6P	0.9474
11	M6P	0.9460
12	M6D	0.9425
13	SG2	0.9396
14	5WN	0.9394
15	ZEC	0.9390
16	6HP	0.9380
17	YF3	0.9378
18	5OO	0.9376
19	F1P	0.9373
20	L21	0.9371
21	STT	0.9370
22	D6G	0.9355
23	CFA	0.9352
24	DHC	0.9347
25	N2M	0.9347
26	A5P	0.9318
27	QMS	0.9315
28	NQH	0.9306
29	4FE	0.9299
30	FER	0.9291
31	TU0	0.9290
32	2HC	0.9289
33	HSX	0.9261
34	GI1	0.9258
35	F5C	0.9256
36	QIF	0.9254
37	SKF	0.9244
38	DEZ	0.9242
39	F1X	0.9231
40	ZIP	0.9230
41	I2E	0.9230
42	RES	0.9219
43	EUE	0.9216
44	I59	0.9213
45	FT6	0.9206
46	M3Q	0.9204
47	F6P	0.9203
48	DY5	0.9198
49	51Y	0.9196
50	HC4	0.9196
51	P81	0.9196
52	GZV	0.9195
53	SG6	0.9195
54	IOS	0.9194
55	ZHA	0.9188
56	HPP	0.9186
57	EVF	0.9185
58	3VX	0.9182
59	DAH	0.9182
60	F06	0.9180
61	IOP	0.9178
62	P2L	0.9177
63	SYE	0.9176
64	RP3	0.9176
65	NBV	0.9175
66	R52	0.9174
67	R5P	0.9174
68	STV	0.9173
69	YOF	0.9170
70	MD6	0.9170
71	2VQ	0.9169
72	363	0.9169
73	657	0.9167
74	2GQ	0.9166
75	ABF	0.9165
76	GJK	0.9164
77	F52	0.9159
78	3Y7	0.9157
79	TA6	0.9153
80	1BW	0.9149
81	S7G	0.9148
82	XCG	0.9147
83	QIV	0.9147
84	CTE	0.9144
85	GXG	0.9144
86	ZON	0.9144
87	TRF	0.9144
88	5TY	0.9144
89	EUH	0.9143
90	GB4	0.9143
91	ENG	0.9141
92	GI3	0.9140
93	68A	0.9139
94	AHC	0.9135
95	SBK	0.9135
96	APS	0.9135
97	ST2	0.9135
98	X48	0.9132
99	MES	0.9129
100	S0W	0.9129
101	NAL	0.9127
102	GO8	0.9126
103	P7Y	0.9126
104	PPT	0.9125
105	TMG	0.9125
106	D1Y	0.9124
107	N91	0.9123
108	EXL	0.9123
109	P80	0.9122
110	4BX	0.9122
111	DX5	0.9122
112	PNP	0.9122
113	NAG	0.9118
114	LTN	0.9116
115	XIF XYP	0.9113
116	790	0.9113
117	XYP XIF	0.9110
118	BP7	0.9109
119	9BF	0.9108
120	AMR	0.9107
121	B41	0.9106
122	9F8	0.9106
123	4OG	0.9106
124	RGG	0.9106
125	MQG	0.9106
126	TRP	0.9105
127	C9M	0.9105
128	ARP	0.9103
129	2FX	0.9102
130	V1T	0.9102
131	E9S	0.9097
132	HBI	0.9097
133	EYJ	0.9095
134	HWD	0.9091
135	5WM	0.9089
136	505	0.9088
137	4Z9	0.9087
138	HA6	0.9086
139	LIP	0.9086
140	8U3	0.9083
141	O2Y	0.9083
142	MPP	0.9080
143	BNX	0.9080
144	IS2	0.9079
145	ALE	0.9078
146	GI4	0.9076
147	DBS	0.9069
148	3D3	0.9069
149	RVE	0.9067
150	T6Z	0.9067
151	NIY	0.9066
152	NTF	0.9066
153	CMU	0.9065
154	CPW	0.9065
155	4Z1	0.9064
156	MMS	0.9064
157	G1P	0.9064
158	5RP	0.9062
159	GB5	0.9060
160	1VQ	0.9059
161	4WF	0.9058
162	61M	0.9057
163	KYN	0.9055
164	CHQ	0.9055
165	P9T	0.9055
166	DTE	0.9054
167	8NX	0.9054
168	SJK	0.9053
169	IL5	0.9053
170	YO5	0.9051
171	FTV	0.9050
172	3M8	0.9049
173	A7H	0.9049
174	7PJ	0.9048
175	FF2	0.9048
176	FPL	0.9048
177	7AP	0.9047
178	EXD	0.9047
179	S0E	0.9043
180	JBZ	0.9043
181	NFM	0.9042
182	EZL	0.9042
183	ESI	0.9041
184	H35	0.9040
185	RP5	0.9040
186	EYY	0.9037
187	ZRK	0.9036
188	XFE	0.9035
189	D8Q	0.9034
190	EYV	0.9034
191	SXX	0.9034
192	ZEZ	0.9033
193	TZP	0.9031
194	5M2	0.9029
195	D9Z	0.9029
196	6Q3	0.9028
197	6J5	0.9026
198	LOT	0.9026
199	MBP	0.9025
200	TOM	0.9024
201	GRX	0.9024
202	4KR	0.9022
203	2KU	0.9021
204	IYR	0.9019
205	LVD	0.9019
206	3IL	0.9018
207	X0T	0.9018
208	KED	0.9018
209	0SY	0.9018
210	878	0.9018
211	57O	0.9018
212	KLV	0.9018
213	TB8	0.9016
214	F90	0.9015
215	JOV	0.9014
216	Y3L	0.9014
217	1PS	0.9014
218	EXR	0.9011
219	K25	0.9011
220	HXY	0.9010
221	FWD	0.9010
222	KF5	0.9010
223	2LT	0.9010
224	96Z	0.9009
225	ALN	0.9009
226	ENO	0.9009
227	WA2	0.9008
228	4XF	0.9008
229	KWB	0.9008
230	6ZX	0.9008
231	8MP	0.9007
232	F40	0.9007
233	IPD	0.9005
234	CCV	0.9005
235	4NS	0.9004
236	S0D	0.9004
237	MJ5	0.9004
238	ONZ	0.9002
239	7EH	0.9002
240	TNX	0.9002
241	TYR	0.9002
242	0FR	0.9001
243	GC2	0.9001
244	THA	0.9001
245	ESX	0.9001
246	EV2	0.9001
247	BY5	0.9000
248	N7I	0.8998
249	5GT	0.8997
250	AKD	0.8996
251	AJD	0.8996
252	NOK	0.8995
253	KTW	0.8995
254	4NP	0.8994
255	I4D	0.8994
256	DTR	0.8993
257	P9E	0.8993
258	N1E	0.8993
259	36E	0.8992
260	K3Q	0.8991
261	B61	0.8990
262	IPT	0.8990
263	LSQ	0.8989
264	FUZ	0.8989
265	AC2	0.8988
266	KYA	0.8988
267	2P3	0.8987
268	1FE	0.8985
269	ITW	0.8981
270	5E5	0.8980
271	5O6	0.8978
272	9E3	0.8978
273	CGW	0.8977
274	92G	0.8977
275	HPT	0.8977
276	BIO	0.8976
277	5OF	0.8976
278	4BY	0.8976
279	MFZ	0.8975
280	4BL	0.8975
281	848	0.8974
282	NPA	0.8972
283	GNM	0.8971
284	TCA	0.8971
285	7ZL	0.8970
286	PMM	0.8970
287	M9N	0.8970
288	RSV	0.8970
289	C82	0.8970
290	7L4	0.8969
291	DK1	0.8969
292	ZYQ	0.8968
293	IAC	0.8967
294	GO2	0.8966
295	OSB	0.8965
296	3JM	0.8965
297	JPQ	0.8964
298	QME	0.8964
299	ZEA	0.8963
300	B56	0.8963
301	AAN	0.8962
302	4CN	0.8962
303	YIP	0.8962
304	HHS	0.8959
305	MUX	0.8957
306	NFK	0.8957
307	3ZB	0.8957
308	833	0.8954
309	PA5	0.8953
310	3SU	0.8952
311	CIY	0.8951
312	4GP	0.8951
313	BWD	0.8951
314	5V7	0.8951
315	GA2	0.8950
316	3XH	0.8950
317	DNA	0.8950
318	B5A	0.8949
319	CWD	0.8948
320	2O8	0.8947
321	F34	0.8947
322	P4L	0.8946
323	EQW	0.8946
324	TYC	0.8945
325	H4B	0.8945
326	GTV	0.8943
327	78U	0.8942
328	ATX	0.8942
329	6QF	0.8942
330	0J5	0.8942
331	HBO	0.8941
332	YIE	0.8940
333	9GP	0.8940
334	2JK	0.8937
335	NHT	0.8936
336	54X	0.8936
337	ANC	0.8936
338	3D8	0.8935
339	CR1	0.8935
340	H5B	0.8935
341	CX4	0.8934
342	4AB	0.8934
343	89J	0.8934
344	GZ2	0.8933
345	C4E	0.8933
346	PQT	0.8933
347	Z25	0.8933
348	3RI	0.8933
349	A6W	0.8933
350	CH8	0.8932
351	5WS	0.8932
352	MXD	0.8932
353	2JX	0.8932
354	MPU	0.8932
355	7SX	0.8932
356	IBC	0.8931
357	9ZE	0.8931
358	GJP	0.8930
359	A4V	0.8930
360	3IP	0.8929
361	UQ1	0.8929
362	9KH	0.8929
363	WV7	0.8928
364	3IB	0.8928
365	CIP	0.8928
366	PVQ	0.8927
367	MAJ	0.8927
368	GRF	0.8925
369	Q5M	0.8925
370	CLU	0.8924
371	6N4	0.8923
372	QUB	0.8922
373	NBG	0.8922
374	SIZ	0.8921
375	3R4	0.8920
376	VC3	0.8920
377	FYR	0.8920
378	IWD	0.8920
379	DTY	0.8919
380	CXH	0.8918
381	5NN	0.8918
382	PVK	0.8917
383	PW1	0.8916
384	TSR	0.8916
385	6FB	0.8916
386	6DP	0.8915
387	X1P	0.8915
388	YIH	0.8914
389	8EU	0.8914
390	PPY	0.8914
391	R4E	0.8912
392	EGR	0.8911
393	GHQ	0.8911
394	JY2	0.8910
395	BQ2	0.8909
396	GDL	0.8909
397	JP2	0.8909
398	YZM	0.8908
399	AZC	0.8907
400	KMY	0.8907
401	22L	0.8907
402	BDI	0.8906
403	4MB	0.8905
404	YX1	0.8905
405	STZ	0.8905
406	NEU	0.8905
407	M3F	0.8904
408	5SP	0.8903
409	6GP	0.8903
410	0J4	0.8903
411	YKG	0.8903
412	M02	0.8902
413	H2B	0.8902
414	LTM	0.8900
415	8D6	0.8899
416	3VS	0.8898
417	TOH	0.8897
418	DER	0.8897
419	PFF	0.8897
420	GFP	0.8895
421	0OK	0.8895
422	BIE	0.8894
423	S0G	0.8894
424	4MX	0.8893
425	12T	0.8893
426	CC5	0.8892
427	PBA	0.8892
428	UNJ	0.8891
429	5AD	0.8890
430	X0U	0.8890
431	327	0.8889
432	PTS	0.8888
433	5WT	0.8886
434	5TO	0.8885
435	5WU	0.8885
436	0UL	0.8885
437	TLM	0.8884
438	EXG	0.8883
439	LL1	0.8883
440	0XR	0.8882
441	GI2	0.8882
442	CKA	0.8881
443	OUB	0.8880
444	DDU	0.8880
445	TL6	0.8879
446	FNA	0.8879
447	LJ3	0.8878
448	TYE	0.8878
449	6KT	0.8877
450	S3C	0.8876
451	GNW	0.8876
452	BL0	0.8875
453	JA5	0.8875
454	KG1	0.8875
455	5OY	0.8874
456	9VQ	0.8874
457	K82	0.8874
458	1X8	0.8874
459	EAE	0.8873
460	S24	0.8873
461	FCW	0.8872
462	BPY	0.8872
463	NLA	0.8872
464	2O6	0.8870
465	0W1	0.8870
466	5LA	0.8870
467	H4E	0.8865
468	M78	0.8865
469	12R	0.8865
470	52F	0.8864
471	1X4	0.8863
472	A5Q	0.8863
473	QUS	0.8862
474	BGN	0.8862
475	JXT	0.8862
476	FZM	0.8861
477	22T	0.8860
478	ZSP	0.8860
479	PE2	0.8859
480	8HC	0.8859
481	3B4	0.8858
482	XIZ	0.8858
483	YTX	0.8858
484	CMG	0.8858
485	B4O	0.8858
486	5VU	0.8857
487	MUR	0.8857
488	LZB	0.8857
489	2K8	0.8856
490	UN4	0.8856
491	3GX	0.8856
492	SB9	0.8855
493	DXK	0.8855
494	KP2	0.8854
495	ZIQ	0.8853
496	8XL	0.8853
497	4KL	0.8853
498	M5H	0.8852
499	C9E	0.8852
500	OQC	0.8852
501	0FK	0.8852
502	56N	0.8851
503	L3L	0.8851
504	1A7	0.8850
505	AVX	0.8850
506	67Y	0.8850
507	ALX	0.8849
508	ANF	0.8849
509	RNK	0.8848
510	XDL XYP	0.8848
511	XYS XYP	0.8847
512	AZY	0.8846
513	EYM	0.8846
514	EV3	0.8846
515	88L	0.8845
516	NPS	0.8845
517	GNR	0.8845
518	2JJ	0.8844
519	XYP XYP	0.8844
520	NIP	0.8844
521	EQA	0.8843
522	2CZ	0.8843
523	5B2	0.8843
524	LP8	0.8843
525	MUK	0.8843
526	C0W	0.8841
527	NEO	0.8841
528	96R	0.8841
529	TZM	0.8840
530	IBM	0.8839
531	OPA	0.8839
532	2UD	0.8838
533	27B	0.8838
534	SLY	0.8838
535	3N1	0.8837
536	S0I	0.8837
537	OTA	0.8837
538	NGA	0.8837
539	4BF	0.8836
540	3D1	0.8836
541	JCZ	0.8836
542	F69	0.8836
543	3L1	0.8835
544	78P	0.8835
545	GC3	0.8834
546	5P3	0.8833
547	1HN	0.8833
548	S0F	0.8833
549	WLH	0.8832
550	36M	0.8831
551	6C9	0.8828
552	OX2	0.8828
553	AA	0.8828
554	BHS	0.8827
555	CG8	0.8827
556	MFR	0.8827
557	S8G	0.8826
558	JYT	0.8826
559	GWM	0.8826
560	DX7	0.8825
561	C53	0.8824
562	HCI	0.8823
563	92O	0.8822
564	B21	0.8822
565	PHI	0.8821
566	XRS	0.8820
567	A1Y	0.8820
568	PRZ	0.8820
569	SOJ	0.8820
570	MTS	0.8819
571	SNO	0.8819
572	BEU	0.8819
573	KOM	0.8818
574	LDP	0.8818
575	GXD	0.8816
576	3GC	0.8816
577	CKX	0.8816
578	AVO	0.8816
579	6C5	0.8815
580	9R5	0.8815
581	SB7	0.8814
582	GL6	0.8814
583	SNY	0.8814
584	Q9P	0.8814
585	L8J	0.8813
586	BZ2	0.8813
587	JXK	0.8812
588	VFG	0.8812
589	2QC	0.8811
590	PO6	0.8810
591	4I8	0.8810
592	7MX	0.8809
593	EVO	0.8809
594	NRA	0.8809
595	AN3	0.8809
596	ICB	0.8809
597	4NZ	0.8809
598	XI7	0.8808
599	LOG	0.8808
600	ESP	0.8808
601	0JD	0.8806
602	E4P	0.8805
603	428	0.8805
604	EYA	0.8804
605	YE7	0.8804
606	8Y7	0.8803
607	K68	0.8802
608	AX3	0.8802
609	6J9	0.8801
610	OLU	0.8801
611	ST3	0.8801
612	FQX	0.8801
613	7I2	0.8800
614	5F1	0.8799
615	OIA	0.8799
616	PIQ	0.8799
617	NGT	0.8799
618	EAT	0.8798
619	2T6	0.8797
620	A5E	0.8797
621	YPN	0.8796
622	FUJ	0.8796
623	7FU	0.8796
624	CKI	0.8795
625	HJB	0.8795
626	6DQ	0.8794
627	4RU	0.8794
628	COL	0.8794
629	JAH	0.8794
630	JV4	0.8794
631	3WJ	0.8793
632	DT7	0.8793
633	ZZZ	0.8793
634	ZRL	0.8793
635	XYP XDN	0.8792
636	NCV	0.8791
637	MST	0.8791
638	344	0.8791
639	JR2	0.8790
640	LO1	0.8790
641	SWX	0.8788
642	N9J	0.8788
643	E9P	0.8787
644	RNO	0.8787
645	HHV	0.8786
646	55D	0.8786
647	T1N	0.8785
648	II4	0.8785
649	JF2	0.8785
650	NFZ	0.8784
651	HNT	0.8784
652	9FH	0.8784
653	PYU	0.8784
654	BPW	0.8783
655	2LB	0.8783
656	TXW	0.8782
657	3J8	0.8782
658	80G	0.8782
659	B2Y	0.8781
660	E7S	0.8781
661	1F1	0.8781
662	ARG	0.8781
663	3DT	0.8780
664	S2C	0.8780
665	535	0.8780
666	14W	0.8779
667	JVA	0.8779
668	SLS	0.8778
669	4FP	0.8776
670	5JT	0.8776
671	NPX	0.8776
672	2PK	0.8776
673	K37	0.8775
674	ZYV	0.8775
675	AZM	0.8775
676	B1J	0.8773
677	DBQ	0.8773
678	DHY	0.8772
679	HHT	0.8772
680	MW5	0.8771
681	0DF	0.8770
682	57D	0.8770
683	HRM	0.8770
684	BHQ	0.8770
685	4CM	0.8769
686	MQB	0.8769
687	K7H	0.8767
688	6L6	0.8766
689	DRG	0.8766
690	IQ5	0.8766
691	ZME	0.8765
692	GJB	0.8765
693	K80	0.8765
694	4TP	0.8764
695	9H2	0.8764
696	AM4	0.8764
697	XQI	0.8764
698	JHY	0.8763
699	S7D	0.8761
700	NGW	0.8761
701	ET0	0.8761
702	1AJ	0.8760
703	BM3	0.8760
704	HX8	0.8759
705	GNG	0.8759
706	78Y	0.8759
707	GHM	0.8759
708	HA5	0.8758
709	Y0V	0.8758
710	AWE	0.8758
711	CP7	0.8757
712	1L5	0.8757
713	6C8	0.8757
714	CUH	0.8756
715	CUT	0.8755
716	15N	0.8755
717	S8A	0.8754
718	J6W	0.8754
719	NDG	0.8754
720	BVS	0.8754
721	PBN	0.8753
722	54E	0.8753
723	ITE	0.8753
724	BK9	0.8753
725	1Q4	0.8752
726	Z21	0.8752
727	NVU	0.8752
728	L22	0.8751
729	NGS	0.8749
730	CKU	0.8749
731	BGU	0.8749
732	GPM	0.8749
733	537	0.8747
734	0OO	0.8746
735	GVY	0.8746
736	PH2	0.8746
737	2L1	0.8745
738	BB4	0.8745
739	VUP	0.8745
740	GP1	0.8745
741	RB2	0.8745
742	42J	0.8744
743	6ZW	0.8744
744	TCR	0.8744
745	L07	0.8743
746	CSN	0.8743
747	W8G	0.8742
748	HQ6	0.8742
749	NYJ	0.8742
750	B23	0.8742
751	9KZ	0.8741
752	BQ5	0.8741
753	PRL	0.8741
754	109	0.8740
755	9JT	0.8739
756	M01	0.8739
757	TWB	0.8739
758	4CF	0.8738
759	5E4	0.8738
760	AXX	0.8737
761	MIG	0.8737
762	D87	0.8737
763	27K	0.8737
764	FHV	0.8736
765	A73	0.8736
766	CG	0.8735
767	AY4	0.8735
768	NWD	0.8735
769	JTH	0.8734
770	E1K	0.8733
771	C09	0.8732
772	S7A	0.8732
773	F6R	0.8732
774	8ZE	0.8732
775	TLG	0.8731
776	DCN	0.8730
777	R9Y	0.8730
778	MIL	0.8730
779	3AK	0.8728
780	8RK	0.8727
781	6SD	0.8727
782	6FZ	0.8727
783	MAG	0.8726
784	BCU	0.8726
785	GNV	0.8725
786	3VQ	0.8725
787	S60	0.8724
788	DDC	0.8723
789	IQZ	0.8723
790	F95	0.8721
791	4LW	0.8721
792	8MO	0.8721
793	K97	0.8721
794	LJ4	0.8720
795	CL9	0.8720
796	8GK	0.8720
797	B52	0.8719
798	2LX	0.8718
799	TSS	0.8718
800	MPK	0.8717
801	MSR	0.8717
802	2PV	0.8716
803	AJG	0.8716
804	8NB	0.8715
805	RCV	0.8714
806	8W9	0.8714
807	BA5	0.8714
808	HJH	0.8714
809	1V1	0.8714
810	OAI	0.8710
811	RYV	0.8710
812	CPZ	0.8710
813	6HO	0.8709
814	512	0.8709
815	AUY	0.8707
816	BBY	0.8707
817	1U7	0.8707
818	092	0.8707
819	AOY	0.8707
820	5GL	0.8706
821	R9J	0.8705
822	9UL	0.8705
823	2L3	0.8704
824	MOK	0.8704
825	PH3	0.8703
826	MJW	0.8702
827	H4B NO	0.8700
828	LR5	0.8700
829	TWO	0.8700
830	NFA	0.8700
831	3JC	0.8700
832	FCD	0.8699
833	JF1	0.8699
834	UAY	0.8698
835	A7K	0.8698
836	DI6	0.8696
837	UFO	0.8696
838	ZYC	0.8693
839	N3W	0.8691
840	PHE	0.8691
841	JB8	0.8690
842	49O	0.8689
843	L1T	0.8689
844	2D2	0.8688
845	3WO	0.8687
846	3WN	0.8687
847	1SS	0.8687
848	25F	0.8687
849	1V3	0.8686
850	LR2	0.8685
851	A6H	0.8683
852	P93	0.8683
853	DPN	0.8683
854	DY8	0.8683
855	4AU	0.8681
856	8HH	0.8681
857	W23	0.8681
858	DUR	0.8681
859	JGB	0.8680
860	2QU	0.8679
861	36Y	0.8679
862	LR8	0.8677
863	N4E	0.8677
864	MPV	0.8677
865	VM1	0.8677
866	7NU	0.8676
867	1V4	0.8675
868	QR2	0.8675
869	A7Q	0.8674
870	977	0.8673
871	AJ1	0.8673
872	1VK	0.8672
873	4QY	0.8671
874	3QO	0.8669
875	28S	0.8668
876	P9I	0.8668
877	H75	0.8668
878	4NR	0.8667
879	R20	0.8667
880	M4B	0.8666
881	DX2	0.8666
882	BZE	0.8666
883	IFG	0.8666
884	HFA	0.8664
885	BZM	0.8664
886	HHR	0.8663
887	5S9	0.8663
888	7M2	0.8661
889	TJM	0.8660
890	EMZ	0.8659
891	8WT	0.8659
892	LQG	0.8658
893	9FE	0.8657
894	9NB	0.8657
895	M3P	0.8657
896	1YO	0.8656
897	IBP	0.8656
898	N2Y	0.8655
899	BRH	0.8654
900	CP6	0.8654
901	28A	0.8654
902	RE4	0.8654
903	BPS	0.8653
904	8OB	0.8652
905	Q9T	0.8652
906	5I5	0.8652
907	FDR	0.8652
908	CX6	0.8652
909	SRO	0.8652
910	Q0K	0.8651
911	DJN	0.8651
912	5DS	0.8650
913	96U	0.8649
914	4AF	0.8648
915	7FF	0.8648
916	OA4	0.8648
917	XJE	0.8648
918	XDK	0.8648
919	SX2	0.8648
920	2L2	0.8647
921	JDN	0.8646
922	108	0.8645
923	IQW	0.8645
924	3C4	0.8645
925	C8O	0.8643
926	N2I	0.8643
927	LNR	0.8643
928	0HN	0.8642
929	PBG	0.8641
930	HL4	0.8641
931	8OE	0.8640
932	BC3	0.8640
933	SQP	0.8639
934	DFL	0.8639
935	5NS	0.8638
936	20D	0.8638
937	HWH	0.8637
938	FSU	0.8636
939	A2G	0.8636
940	9CE	0.8636
941	0QW	0.8636
942	MZM	0.8636
943	PQZ	0.8635
944	SDF	0.8635
945	7M5	0.8633
946	KWQ	0.8632
947	4Z3	0.8632
948	92P	0.8631
949	YZ9	0.8631
950	8VR	0.8631
951	AU8	0.8630
952	0HO	0.8630
953	SSY	0.8630
954	S62	0.8629
955	JND	0.8629
956	AYS	0.8628
957	IPO	0.8628
958	DNC	0.8628
959	5F5	0.8628
960	JAW	0.8627
961	PUE	0.8626
962	2T4	0.8625
963	X2M	0.8625
964	RGK	0.8623
965	OOG	0.8621
966	692	0.8621
967	BZJ	0.8621
968	TYL	0.8621
969	H7Y	0.8620
970	CBE	0.8619
971	LWS	0.8618
972	CH9	0.8618
973	5F8	0.8618
974	AM1	0.8618
975	MS0	0.8617
976	22F	0.8616
977	6VD	0.8616
978	SCE	0.8615
979	7A9	0.8614
980	4NO	0.8613
981	TQU	0.8612
982	XG1	0.8611
983	LQ2	0.8611
984	5FL	0.8609
985	BCK	0.8609
986	1SV	0.8609
987	6PG	0.8608
988	7QY	0.8608
989	CLZ	0.8608
990	RDT	0.8607
991	3F4	0.8607
992	47V	0.8606
993	AEH	0.8602
994	PJW	0.8602
995	SZ5	0.8602
996	JGY	0.8602
997	7D7	0.8601
998	16G	0.8601
999	E3X	0.8601
1000	3W8	0.8600
1001	QZ8	0.8599
1002	4LV	0.8599
1003	P4T	0.8599
1004	3WK	0.8599
1005	14Z	0.8599
1006	1BN	0.8599
1007	ODK	0.8598
1008	F4E	0.8598
1009	21D	0.8596
1010	B0K	0.8595
1011	F02	0.8595
1012	KLK	0.8594
1013	GSY	0.8593
1014	2QV	0.8593
1015	R2P	0.8593
1016	ETS	0.8592
1017	M1Z	0.8591
1018	VGS	0.8590
1019	772	0.8590
1020	2WU	0.8589
1021	PRO GLY	0.8589
1022	NK5	0.8588
1023	2J1	0.8588
1024	4EU	0.8588
1025	GNJ	0.8588
1026	HX4	0.8587
1027	JRB	0.8586
1028	6FG	0.8586
1029	KLS	0.8584
1030	11X	0.8581
1031	W81	0.8581
1032	QBP	0.8580
1033	RKV	0.8579
1034	MNP	0.8579
1035	3A9	0.8578
1036	6C4	0.8575
1037	EE8	0.8574
1038	JPB	0.8574
1039	THM	0.8573
1040	2AN	0.8572
1041	G14	0.8570
1042	IQU	0.8569
1043	3G3	0.8567
1044	S98	0.8567
1045	XEN	0.8566
1046	JF8	0.8566
1047	6NT	0.8565
1048	AP6	0.8564
1049	AMQ	0.8564
1050	CUQ	0.8563
1051	68B	0.8562
1052	DCZ	0.8562
1053	FYJ	0.8561
1054	1M2	0.8560
1055	56D	0.8558
1056	L46	0.8557
1057	BNF	0.8556
1058	QQQ	0.8554
1059	FMQ	0.8551
1060	C2M	0.8550
1061	AEG	0.8547
1062	BP3	0.8545
1063	49P	0.8543
1064	API	0.8541
1065	6PB	0.8539
1066	B86	0.8536
1067	774	0.8535
1068	NE1	0.8533
1069	3WL	0.8530
1070	25O	0.8523
1071	2F6	0.8508
1072	XYS XYS	0.8506
1073	O9Q	0.8505

Ligand no: 2; Ligand: TLP; Similar ligands found: 18

No:	Ligand	Similarity coefficient
1	PLP ALO	0.9728
2	SER PLP	0.9495
3	PLP CYS	0.9246
4	HCP	0.9218
5	MPM	0.9209
6	PLI	0.9120
7	MET PLP	0.9051
8	PLP 2ML	0.9010
9	KET	0.9007
10	ASP PLP	0.9007
11	PLP MET	0.9000
12	PM9	0.8914
13	3QP	0.8851
14	L7N	0.8840
15	LEU PLP	0.8833
16	PLP GLY	0.8714
17	PLP AOA	0.8704
18	GLY PLP	0.8593

Similar Binding Sites (Proteins are less than 50% similar to leader)

Pocket No.: 1; Query (leader) PDB : 1LW4; Ligand: TLP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 1) in the query (biounit: 1lw4.bio1) has 21 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 2; Query (leader) PDB : 1LW4; Ligand: TLP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 2) in the query (biounit: 1lw4.bio1) has 21 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 3; Query (leader) PDB : 1LW4; Ligand: TLP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 3) in the query (biounit: 1lw4.bio1) has 20 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 4; Query (leader) PDB : 1LW4; Ligand: PLP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 4) in the query (biounit: 1lw4.bio1) has 19 residues
No:	Leader PDB	Ligand	Sequence Similarity

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