Receptor
PDB id Resolution Class Description Source Keywords
1PQ9 2.1 Å NON-ENZYME: SIGNAL_HORMONE HUMAN LXR BETA HORMONE RECEPTOR COMPLEXED WITH T0901317 COMP HOMO SAPIENS LXRB+T0901317 SPLIT TRANSCRIPTION REGULATION
Ref.: THE THREE-DIMENSIONAL STRUCTURE OF THE LIVER X RECE REVEALS A FLEXIBLE LIGAND-BINDING POCKET THAT CAN ACCOMMODATE FUNDAMENTALLY DIFFERENT LIGANDS. J.BIOL.CHEM. V. 278 38821 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
44B A:1501;
B:2501;
C:3501;
D:4501;
 Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
 submit data
341.173 C11 H8 F9 N O c1cc(...
BNS A:1500;
B:2500;
C:3500;
D:4500;
 Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
 submit data
158.175 C6 H6 O3 S c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3KFC 2.4 Å NON-ENZYME: SIGNAL_HORMONE COMPLEX STRUCTURE OF LXR WITH AN AGONIST HOMO SAPIENS NUCLEAR RECEPTOR LXR LIVER X RECEPTOR LXR AGONIST LXR LIDNA-BINDING METAL-BINDING NUCLEUS RECEPTOR TRANSCRIPTIOTRANSCRIPTION REGULATION ZINC-FINGER
Ref.: 4-(3-ARYLOXYARYL)QUINOLINE SULFONES ARE POTENT LIVE RECEPTOR AGONISTS. BIOORG.MED.CHEM.LETT. V. 20 209 2010
Members (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 289 families.
1 1PQ9 - BNS C6 H6 O3 S c1ccc(cc1)....
2 4RAK Ki = 14 nM 652 C28 H29 Cl N2 O3 S CC(C)(c1cc....
3 6S4T Ki = 0.00000079 M KVB C32 H24 F3 N O3 c1ccc(cc1)....
4 6K9H Ki = 600 nM D40 C22 H24 N2 O3 CC(C)(C)OC....
5 1UPV - 444 C17 H12 F9 N O3 S c1ccc(cc1)....
6 1PQ6 - 965 C33 H31 Cl F3 N O3 c1ccc(cc1)....
7 6S4N Kd = 1.6 uM KUW C24 H27 Cl N4 O5 S CC(C)N1C(=....
8 1UPW - 444 C17 H12 F9 N O3 S c1ccc(cc1)....
9 5JY3 Ki = 12 nM 6OX C29 H28 Cl2 F2 N2 O4 S CC(C)(c1cn....
10 3KFC ic50 = 2.8 nM 61X C23 H16 F3 N O3 S CS(=O)(=O)....
11 6S5K Ki = 0.00000079 M KWE C28 H28 N2 O2 c1ccc(cc1)....
70% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 214 families.
1 1PQ9 - BNS C6 H6 O3 S c1ccc(cc1)....
2 4RAK Ki = 14 nM 652 C28 H29 Cl N2 O3 S CC(C)(c1cc....
3 6S4T Ki = 0.00000079 M KVB C32 H24 F3 N O3 c1ccc(cc1)....
4 6K9H Ki = 600 nM D40 C22 H24 N2 O3 CC(C)(C)OC....
5 1UPV - 444 C17 H12 F9 N O3 S c1ccc(cc1)....
6 1PQ6 - 965 C33 H31 Cl F3 N O3 c1ccc(cc1)....
7 6S4N Kd = 1.6 uM KUW C24 H27 Cl N4 O5 S CC(C)N1C(=....
8 1UPW - 444 C17 H12 F9 N O3 S c1ccc(cc1)....
9 5JY3 Ki = 12 nM 6OX C29 H28 Cl2 F2 N2 O4 S CC(C)(c1cn....
10 3KFC ic50 = 2.8 nM 61X C23 H16 F3 N O3 S CS(=O)(=O)....
11 6S5K Ki = 0.00000079 M KWE C28 H28 N2 O2 c1ccc(cc1)....
50% Homology Family (40)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 220 families.
1 4Q0A Kd = 0.33 uM 4OA C24 H40 O3 C[C@H](CCC....
2 3A3Z - 2MV C29 H46 O4 C[C@H]1[C@....
3 1IE8 - KH1 C29 H48 O4 CCC(CC)(CC....
4 2HAS - C3O C30 H50 O4 CCCO[C@H]1....
5 1S0Z - EB1 C30 H46 O3 CCC(CC)(C=....
6 3AZ1 - DS2 C27 H38 O5 CCC(CC)(c1....
7 1IE9 - VDX C27 H44 O3 C[C@H](CCC....
8 2HAM - C33 C30 H50 O3 CCC[C@H]1[....
9 2HB8 - MVD C28 H46 O3 C[C@H]1[C@....
10 3CS4 - COV C28 H44 O4 C[C@]12CCC....
11 1S19 - MC9 C27 H40 O3 C[C@H](C=C....
12 3M7R - VDX C27 H44 O3 C[C@H](CCC....
13 3A40 - 23R C29 H46 O4 C[C@H]1[C@....
14 3AUR - CA9 C27 H42 O3 C[C@H]1[C@....
15 3KPZ - ZNE C28 H41 N O3 S C[C@H](CCC....
16 1TXI - TX5 C26 H40 O3 C[C@H](CC#....
17 1DB1 Kd = 0.55 nM VDX C27 H44 O3 C[C@H](CCC....
18 4G2I - 0VQ C25 H26 F6 O3 CC/C(=CC=C....
19 3CS6 - 0CO C28 H44 O4 C[C@]12CCC....
20 3AZ2 - DS3 C30 H44 O5 CCC(CC)(c1....
21 3AZ3 - DS6 C31 H46 O5 CCC(CC)(c1....
22 5YT2 - 90O C29 H48 O4 C[C@H](CCC....
23 5GIE Kd = 769.2 nM VDP C37 H53 N O4 C[C@H](C[C....
24 2HB7 - O1C C30 H50 O4 C[C@H](CCC....
25 3VHW - VHW C34 H50 O7 CCC1(CC/C(....
26 2HAR - OCC C30 H50 O5 C[C@H](CCC....
27 5GID Kd = 769.2 nM VDP C37 H53 N O4 C[C@H](C[C....
28 3TKC - FMV C28 H40 O4 C[C@H](c1c....
29 4ITE - TEY C30 H48 N4 O3 C[C@H](CCC....
30 1PQ9 - BNS C6 H6 O3 S c1ccc(cc1)....
31 4RAK Ki = 14 nM 652 C28 H29 Cl N2 O3 S CC(C)(c1cc....
32 6S4T Ki = 0.00000079 M KVB C32 H24 F3 N O3 c1ccc(cc1)....
33 6K9H Ki = 600 nM D40 C22 H24 N2 O3 CC(C)(C)OC....
34 1UPV - 444 C17 H12 F9 N O3 S c1ccc(cc1)....
35 1PQ6 - 965 C33 H31 Cl F3 N O3 c1ccc(cc1)....
36 6S4N Kd = 1.6 uM KUW C24 H27 Cl N4 O5 S CC(C)N1C(=....
37 1UPW - 444 C17 H12 F9 N O3 S c1ccc(cc1)....
38 5JY3 Ki = 12 nM 6OX C29 H28 Cl2 F2 N2 O4 S CC(C)(c1cn....
39 3KFC ic50 = 2.8 nM 61X C23 H16 F3 N O3 S CS(=O)(=O)....
40 6S5K Ki = 0.00000079 M KWE C28 H28 N2 O2 c1ccc(cc1)....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 44B; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 44B 1 1
Ligand no: 2; Ligand: BNS; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 BNS 1 1
2 FB2 0.521739 0.65
3 A09 0.464286 0.622222
Similar Ligands (3D)
Ligand no: 1; Ligand: 44B; Similar ligands found: 1
No: Ligand Similarity coefficient
1 T11 0.8877
Ligand no: 2; Ligand: BNS; Similar ligands found: 978
No: Ligand Similarity coefficient
1 PBC 1.0000
2 NBZ 1.0000
3 UNU 1.0000
4 NTN 1.0000
5 BEZ 1.0000
6 NIO 1.0000
7 PZA 1.0000
8 BAM 1.0000
9 BEN 1.0000
10 NCA 1.0000
11 6PC 1.0000
12 SS2 0.9994
13 QSC 0.9974
14 M58 0.9967
15 AC0 0.9892
16 VGL 0.9878
17 YCP 0.9855
18 RSO 0.9831
19 SMV 0.9821
20 SS1 0.9776
21 TZC 0.9769
22 JBN 0.9739
23 FOA 0.9727
24 C21 0.9715
25 PYC 0.9711
26 TP5 0.9709
27 2PC 0.9705
28 PHB 0.9699
29 JZ5 0.9695
30 NPO 0.9694
31 ISZ 0.9688
32 PMB 0.9685
33 GAB 0.9685
34 CFI 0.9682
35 FEH 0.9681
36 IT2 0.9670
37 MXN 0.9669
38 1Y6 0.9668
39 BHO 0.9664
40 PRO 0.9653
41 BE2 0.9653
42 ABN 0.9650
43 SAL 0.9647
44 271 0.9646
45 PAB 0.9646
46 FAN 0.9639
47 CXF 0.9634
48 MRZ 0.9633
49 P72 0.9633
50 IP0 0.9632
51 AMC 0.9631
52 PBZ 0.9629
53 JZ7 0.9622
54 7N0 0.9621
55 40E 0.9614
56 I1E 0.9611
57 QY9 0.9604
58 3AB 0.9599
59 HY1 0.9597
60 AC6 0.9596
61 3NT 0.9596
62 3U4 0.9594
63 PYJ 0.9591
64 282 0.9590
65 MNN 0.9585
66 4MA 0.9583
67 VNJ 0.9582
68 OAA 0.9581
69 ES6 0.9580
70 53C 0.9580
71 FBM 0.9576
72 Z82 0.9575
73 SYN 0.9574
74 GAG 0.9563
75 HBD 0.9563
76 PZI 0.9562
77 1MR 0.9557
78 F9P 0.9551
79 APY 0.9549
80 1DJ 0.9548
81 9CL 0.9546
82 B24 0.9545
83 COI 0.9542
84 PEA 0.9541
85 3SK 0.9538
86 HBX 0.9538
87 PAC 0.9536
88 NMJ 0.9536
89 3OC 0.9527
90 273 0.9527
91 NIZ 0.9523
92 NBE 0.9522
93 60P 0.9522
94 FQI 0.9521
95 PRS 0.9520
96 4CS 0.9518
97 FPI 0.9517
98 OK7 0.9517
99 PYF 0.9515
100 URQ 0.9513
101 14J 0.9512
102 5AC 0.9508
103 PY7 0.9507
104 7WG 0.9507
105 OVV 0.9505
106 PEL 0.9504
107 JKE 0.9499
108 1WD 0.9497
109 4SV 0.9495
110 3HB 0.9493
111 LMR 0.9492
112 WCE 0.9491
113 HBA 0.9484
114 DYA 0.9480
115 IDM 0.9474
116 ZBT 0.9473
117 TZL 0.9473
118 HIO 0.9468
119 7A8 0.9461
120 7WV 0.9459
121 GBD 0.9457
122 JAB 0.9457
123 PHU 0.9455
124 UYA 0.9455
125 GJZ 0.9453
126 54D 0.9452
127 1DU 0.9452
128 268 0.9450
129 MLT 0.9443
130 F05 0.9442
131 SW7 0.9440
132 258 0.9437
133 XBT 0.9435
134 TFB 0.9433
135 OXQ 0.9427
136 UY7 0.9426
137 2RH 0.9422
138 6M4 0.9422
139 LEU 0.9419
140 ASN 0.9418
141 3BZ 0.9415
142 K7M 0.9413
143 FBW 0.9412
144 DPR 0.9407
145 ASP 0.9406
146 TLA 0.9405
147 BE7 0.9394
148 8GC 0.9393
149 TEO 0.9387
150 CEE 0.9381
151 DBH 0.9377
152 TZE 0.9376
153 T2C 0.9376
154 CRN 0.9375
155 XCZ 0.9370
156 DHB 0.9370
157 TSU 0.9369
158 PCA 0.9360
159 4JL 0.9359
160 4VP 0.9357
161 SRT 0.9354
162 SAN 0.9353
163 3HA 0.9348
164 FBJ 0.9347
165 P9P 0.9346
166 4NC 0.9345
167 M6W 0.9344
168 JYD 0.9342
169 2CK 0.9342
170 BP9 0.9341
171 T9G 0.9340
172 FE DB1 0.9339
173 HZP 0.9339
174 FBV 0.9335
175 1PT 0.9335
176 9TW 0.9330
177 DAS 0.9329
178 4J8 0.9326
179 HSM 0.9324
180 FUM 0.9318
181 MZW 0.9316
182 3F0 0.9314
183 FBS 0.9312
184 OTR 0.9309
185 NXA 0.9309
186 SIN 0.9307
187 1P3 0.9306
188 TPA 0.9301
189 4P5 0.9299
190 FB1 0.9298
191 NYL 0.9297
192 FBA 0.9295
193 1SA 0.9294
194 3M0 0.9293
195 MUC 0.9291
196 DS0 0.9287
197 SYG 0.9285
198 HDH 0.9285
199 XM0 0.9281
200 GLU 0.9279
201 ORO 0.9277
202 9X7 0.9276
203 AMS 0.9276
204 AAS 0.9276
205 FP1 0.9275
206 K34 0.9275
207 QSB 0.9275
208 3SL 0.9274
209 HYP 0.9273
210 INO 0.9272
211 93K 0.9272
212 51R 0.9271
213 IHG 0.9271
214 URS 0.9271
215 HVQ 0.9267
216 J9T 0.9267
217 C2B 0.9265
218 IHB 0.9264
219 SHA 0.9261
220 FCR 0.9260
221 BVC 0.9260
222 BZX 0.9260
223 M4T 0.9259
224 OHG 0.9258
225 9RW 0.9253
226 R9S 0.9252
227 ITN 0.9252
228 49F 0.9245
229 2LP 0.9244
230 PEP 0.9243
231 8K2 0.9241
232 2HO 0.9241
233 JZ1 0.9240
234 069 0.9237
235 NVI 0.9237
236 MYJ 0.9235
237 4JM 0.9232
238 4FA 0.9232
239 1DQ 0.9231
240 HY3 0.9230
241 MAE 0.9227
242 GRO 0.9226
243 BVG 0.9225
244 CHB 0.9225
245 98J 0.9224
246 AEF 0.9222
247 YRL 0.9221
248 JZ3 0.9221
249 BHA 0.9220
250 BSX 0.9219
251 KIV 0.9217
252 AHB 0.9215
253 R8A 0.9214
254 N4B 0.9213
255 KOJ 0.9213
256 1DV 0.9211
257 IPB 0.9211
258 AHR 0.9210
259 261 0.9210
260 PPR 0.9210
261 GZ3 0.9210
262 SJ5 0.9209
263 AL0 0.9207
264 ROR 0.9203
265 NK 0.9203
266 1LN 0.9203
267 173 0.9202
268 RBJ 0.9202
269 RMN 0.9201
270 SPA 0.9199
271 IOM 0.9198
272 JZ4 0.9195
273 GUA 0.9195
274 265 0.9194
275 45L 0.9192
276 PRY 0.9190
277 C2A 0.9189
278 DFB 0.9189
279 DOB 0.9188
280 HX2 0.9188
281 5NU 0.9188
282 GYE 0.9187
283 D1X 0.9187
284 PRI 0.9187
285 51F 0.9187
286 HSE 0.9185
287 SMN 0.9185
288 IZC 0.9185
289 FA0 0.9184
290 HPS 0.9180
291 MZ0 0.9180
292 286 0.9179
293 5CU 0.9178
294 4MV 0.9177
295 HHA 0.9173
296 HL5 0.9172
297 717 0.9170
298 TH7 0.9168
299 HPA 0.9166
300 MLE 0.9166
301 H8N 0.9165
302 8OZ 0.9165
303 NVA 0.9162
304 PRA 0.9160
305 XX2 0.9160
306 THR 0.9160
307 264 0.9159
308 PKU 0.9156
309 4M0 0.9155
310 NMG 0.9153
311 4XR 0.9153
312 RHU 0.9151
313 CIZ 0.9148
314 1AB 0.9148
315 JZ9 0.9144
316 O7U 0.9144
317 174 0.9142
318 BRT 0.9139
319 DHK 0.9137
320 MAK 0.9137
321 K5W 0.9136
322 SPV 0.9136
323 G3H 0.9135
324 G3P 0.9135
325 HCS 0.9135
326 7MU 0.9134
327 826 0.9130
328 LNR 0.9127
329 HSO 0.9126
330 IFM 0.9126
331 9YL 0.9126
332 R2B 0.9125
333 R67 0.9125
334 0R0 0.9124
335 DOR 0.9123
336 AZF 0.9123
337 1LQ 0.9122
338 OXZ 0.9122
339 QMP 0.9121
340 DHS 0.9119
341 2AL 0.9119
342 5HN 0.9118
343 KYD 0.9117
344 RB5 0.9117
345 XYL 0.9117
346 GTQ 0.9116
347 LT1 0.9115
348 RSF 0.9115
349 RIB 0.9114
350 SC2 0.9113
351 M3H 0.9112
352 TAR 0.9111
353 BNF 0.9111
354 I4B 0.9107
355 JFJ 0.9107
356 EDG 0.9104
357 L99 0.9104
358 PEQ 0.9102
359 IQ0 0.9100
360 DEN 0.9100
361 OXC 0.9098
362 2EZ 0.9097
363 RBL 0.9092
364 G2H 0.9091
365 DCL 0.9091
366 JBE 0.9090
367 4JU 0.9090
368 IND 0.9087
369 2CO 0.9086
370 69O 0.9085
371 9TZ 0.9083
372 54G 0.9083
373 SYC 0.9082
374 WOT 0.9080
375 UGC 0.9077
376 JLZ 0.9076
377 SVD 0.9074
378 5RG 0.9074
379 ORN 0.9073
380 EKZ 0.9069
381 6M1 0.9069
382 4SX 0.9068
383 AX7 0.9067
384 4CH 0.9066
385 3QM 0.9065
386 7B4 0.9065
387 5M0 0.9063
388 1GP 0.9063
389 KTA 0.9063
390 5MK 0.9059
391 ASC 0.9058
392 SVN 0.9056
393 URP 0.9056
394 AGK 0.9055
395 IPZ 0.9055
396 6F0 0.9054
397 X0V 0.9054
398 MLA 0.9053
399 LZ1 0.9053
400 GRE 0.9052
401 LDP 0.9050
402 2AS 0.9050
403 6M9 0.9050
404 270 0.9049
405 EDR 0.9048
406 NLE 0.9048
407 BZI 0.9047
408 BML 0.9045
409 269 0.9044
410 34D 0.9044
411 2MI 0.9040
412 SHF 0.9040
413 13P 0.9040
414 HC4 0.9039
415 2MH 0.9039
416 XUL 0.9039
417 278 0.9037
418 GIF 0.9035
419 QUZ 0.9035
420 CXL 0.9034
421 TAG 0.9033
422 MLI 0.9032
423 NPY 0.9031
424 QDK 0.9030
425 HMH 0.9030
426 PIY 0.9029
427 AKG 0.9029
428 ABV 0.9027
429 B85 0.9027
430 2PG 0.9026
431 LYL 0.9025
432 SX1 0.9023
433 GXE 0.9021
434 H95 0.9020
435 4ZA 0.9020
436 ADE 0.9017
437 OHP 0.9016
438 IFP 0.9015
439 3FH 0.9015
440 GP9 0.9014
441 B40 0.9013
442 URF 0.9013
443 4JT 0.9012
444 24B 0.9012
445 0R1 0.9012
446 NNO 0.9010
447 DHR 0.9009
448 PBA 0.9009
449 DGN 0.9008
450 4NM 0.9008
451 PGA 0.9007
452 PBE 0.9007
453 ZXD 0.9007
454 BZF 0.9006
455 23W 0.9006
456 PIM 0.9002
457 0V5 0.9001
458 KMT 0.8999
459 4AA 0.8999
460 GVH 0.8998
461 HGW 0.8996
462 SD4 0.8993
463 TTO 0.8993
464 IMR 0.8993
465 6CS 0.8993
466 2DR 0.8989
467 PSE 0.8989
468 HAI 0.8988
469 MPI 0.8987
470 ASO 0.8987
471 23A 0.8985
472 IF7 0.8985
473 BZ3 0.8984
474 CSS 0.8984
475 LDU 0.8984
476 3HL 0.8983
477 GLC 0.8983
478 BDP 0.8982
479 8CL 0.8981
480 HDA 0.8980
481 SNE 0.8977
482 ANN 0.8976
483 4A3 0.8976
484 GLN 0.8976
485 PG3 0.8975
486 P3K 0.8974
487 DGJ 0.8971
488 GLY ALA 0.8970
489 RM1 0.8970
490 Q88 0.8969
491 280 0.8967
492 G4D 0.8967
493 7HP 0.8967
494 CN0 0.8965
495 449 0.8965
496 FBT 0.8965
497 GZL 0.8965
498 P92 0.8963
499 5QY 0.8961
500 XSP 0.8960
501 4FH 0.8958
502 R1X 0.8954
503 A13 0.8954
504 HHN 0.8953
505 FHB 0.8953
506 MCT 0.8952
507 J9Q 0.8951
508 WBU 0.8951
509 FPY 0.8951
510 ZZ3 0.8950
511 DQY 0.8950
512 ABU 0.8947
513 0RW 0.8947
514 CP 0.8946
515 0CT 0.8946
516 3HR 0.8946
517 R9M 0.8945
518 93B 0.8945
519 LLQ 0.8944
520 MBN 0.8944
521 TYL 0.8942
522 GDE 0.8939
523 G2F 0.8939
524 PIH 0.8939
525 MRY 0.8938
526 3AL 0.8936
527 3HM 0.8936
528 ONL 0.8935
529 FBU 0.8935
530 CMS 0.8935
531 9EW 0.8934
532 I3A 0.8933
533 HQE 0.8932
534 DA1 0.8931
535 VAL 0.8931
536 PCR 0.8930
537 S0H 0.8930
538 1P8 0.8929
539 FPN 0.8928
540 SAF 0.8927
541 E5X 0.8927
542 AW5 0.8924
543 ILE 0.8923
544 24W 0.8922
545 C5J 0.8922
546 XIY 0.8922
547 5MB 0.8921
548 HMU 0.8920
549 ICF 0.8919
550 EHM 0.8919
551 3PY 0.8919
552 2IM 0.8917
553 NOJ 0.8917
554 9ON 0.8917
555 4HO 0.8916
556 2FY 0.8916
557 NSP 0.8916
558 KBB 0.8915
559 MED 0.8915
560 4HS 0.8914
561 2IT 0.8913
562 GGL 0.8913
563 2HG 0.8912
564 3XX 0.8912
565 LG4 0.8911
566 5OB 0.8911
567 MJ2 0.8910
568 CYH 0.8907
569 HIS 0.8906
570 THE 0.8906
571 PLQ 0.8905
572 AMH 0.8904
573 FA1 0.8904
574 J1Z 0.8902
575 AAE 0.8902
576 RNT 0.8899
577 2AC 0.8899
578 14O 0.8895
579 42J 0.8895
580 IPH 0.8895
581 H42 0.8895
582 IFL 0.8894
583 DBX 0.8892
584 ICC 0.8892
585 TDR 0.8891
586 5H1 0.8891
587 IPU 0.8891
588 AC5 0.8890
589 SWD 0.8890
590 4WL 0.8889
591 DE5 0.8889
592 4ZE 0.8889
593 SEP 0.8888
594 F60 0.8887
595 284 0.8885
596 PXY 0.8885
597 92K 0.8885
598 263 0.8885
599 25R 0.8885
600 PGH 0.8885
601 HX3 0.8884
602 RJY 0.8884
603 NCT 0.8883
604 TIU 0.8882
605 2ZV 0.8882
606 RNS 0.8882
607 OGA 0.8882
608 97T 0.8881
609 HLR 0.8881
610 FYU 0.8880
611 OVP 0.8880
612 LER 0.8878
613 S76 0.8876
614 2K4 0.8876
615 2FT 0.8875
616 MWM 0.8875
617 ECE 0.8874
618 IVA 0.8874
619 JAE 0.8873
620 XBZ 0.8873
621 4JJ 0.8873
622 1MC 0.8872
623 4CL 0.8869
624 FK8 0.8869
625 6AI 0.8869
626 F81 0.8867
627 SKM 0.8867
628 47J 0.8866
629 4JP 0.8865
630 NEQ 0.8864
631 6OT 0.8862
632 ZGL 0.8861
633 XYD 0.8860
634 ALO 0.8860
635 3V4 0.8859
636 PHE 0.8859
637 5MI 0.8858
638 A1U 0.8857
639 QOS 0.8857
640 BTE 0.8857
641 XLS 0.8856
642 EYK 0.8855
643 MS9 0.8854
644 ES2 0.8852
645 CYS 0.8851
646 DMG 0.8850
647 V1L 0.8849
648 IJZ 0.8848
649 URA 0.8847
650 COU 0.8846
651 CRS 0.8845
652 EV0 0.8845
653 NOY 0.8845
654 3PG 0.8844
655 JBK 0.8844
656 TTL 0.8843
657 Q6T 0.8842
658 H3M 0.8842
659 8WO 0.8842
660 HGQ 0.8841
661 Z6J 0.8840
662 J9N 0.8840
663 34A 0.8839
664 4H2 0.8839
665 TH0 0.8839
666 ES9 0.8839
667 C2U 0.8839
668 2MP 0.8838
669 42C 0.8837
670 MZG 0.8837
671 MET 0.8836
672 LCN 0.8836
673 ZZT 0.8836
674 4P0 0.8835
675 PYD 0.8835
676 ICP 0.8835
677 2A7 0.8834
678 FK1 0.8834
679 4JN 0.8833
680 1SQ 0.8833
681 HIU 0.8831
682 OVM 0.8830
683 4XV 0.8828
684 PMF 0.8826
685 ODO 0.8825
686 APG 0.8825
687 FOT 0.8825
688 23J 0.8825
689 HVK 0.8823
690 1DW 0.8822
691 4VY 0.8822
692 275 0.8820
693 JZ2 0.8820
694 3AP 0.8820
695 AS3 0.8820
696 2KT 0.8820
697 4Z4 0.8818
698 AKB 0.8817
699 HEW 0.8817
700 N2Z 0.8817
701 GAL 0.8816
702 SN4 0.8815
703 PAF 0.8812
704 HXX 0.8812
705 BR9 0.8811
706 B2J 0.8810
707 HQJ 0.8810
708 LEA 0.8809
709 OPE 0.8809
710 3CH 0.8808
711 4BZ 0.8808
712 HPY 0.8807
713 27Y 0.8807
714 4AP 0.8806
715 JB5 0.8806
716 G5V 0.8805
717 N5J 0.8805
718 RUU 0.8804
719 RCO 0.8804
720 XRG 0.8803
721 5RN 0.8803
722 3ID 0.8803
723 MWJ 0.8802
724 11S 0.8802
725 H4N 0.8802
726 BVF 0.8801
727 1M2 0.8798
728 03V 0.8797
729 GOJ 0.8796
730 5UC 0.8796
731 P2D 0.8796
732 3IT 0.8796
733 DMD 0.8795
734 FW5 0.8794
735 GLY GLY 0.8794
736 FUB 0.8794
737 A29 0.8792
738 M2H 0.8789
739 B3R 0.8788
740 TM7 0.8788
741 DIU 0.8788
742 7VD 0.8787
743 IOL 0.8787
744 52C 0.8786
745 4XS 0.8786
746 82I 0.8785
747 2AP 0.8784
748 AEG 0.8784
749 GVG 0.8784
750 SGL 0.8783
751 BEW 0.8783
752 JF6 0.8782
753 MR1 0.8781
754 M45 0.8781
755 MNM 0.8781
756 A2Q 0.8781
757 0TR 0.8781
758 5WV 0.8780
759 8H8 0.8780
760 HHH 0.8780
761 PAH 0.8780
762 E7Z 0.8777
763 DTL 0.8777
764 2CL 0.8777
765 7HQ 0.8777
766 BPN 0.8777
767 2YU 0.8776
768 5JC 0.8776
769 MLM 0.8775
770 XYP 0.8775
771 10L 0.8774
772 3Z7 0.8774
773 LG3 0.8773
774 285 0.8773
775 2XX 0.8773
776 5MH 0.8771
777 CIG 0.8771
778 3HP 0.8771
779 L5V 0.8771
780 JBH 0.8771
781 PAE 0.8768
782 1NP 0.8768
783 M3T 0.8765
784 HT4 0.8764
785 ICO 0.8763
786 ES5 0.8763
787 DUC 0.8762
788 CTS 0.8762
789 1LM 0.8761
790 5IQ 0.8761
791 ISN 0.8760
792 4FS 0.8760
793 0OC 0.8759
794 F31 0.8758
795 HRZ 0.8758
796 X1S 0.8758
797 L3Q 0.8757
798 CWM 0.8757
799 E60 0.8757
800 1DH 0.8754
801 A8C 0.8754
802 JPZ 0.8754
803 KG7 0.8754
804 AKH 0.8753
805 DGY 0.8753
806 5Q0 0.8752
807 L60 0.8751
808 2AQ 0.8751
809 ES0 0.8750
810 67N 0.8750
811 1F1 0.8750
812 ADA 0.8747
813 AT3 0.8746
814 HHQ 0.8746
815 MWP 0.8745
816 9PO 0.8744
817 HL4 0.8743
818 KKN 0.8743
819 4HM 0.8742
820 ES1 0.8742
821 4YS 0.8741
822 25T 0.8741
823 BCU 0.8739
824 DSN 0.8739
825 MZB 0.8737
826 43M 0.8736
827 RUY 0.8736
828 O72 0.8735
829 5SG 0.8735
830 LG5 0.8735
831 8NY 0.8733
832 CYT 0.8730
833 PLU 0.8730
834 TB6 0.8729
835 OCH 0.8729
836 M1A 0.8729
837 BGC 0.8727
838 LGA 0.8727
839 GG6 0.8726
840 26D 0.8726
841 H76 0.8725
842 PZM 0.8724
843 2D0 0.8723
844 9HX 0.8722
845 8GF 0.8720
846 2BG 0.8719
847 IDH 0.8719
848 CPZ 0.8719
849 2F6 0.8717
850 MEQ 0.8717
851 PIS 0.8716
852 6MP 0.8715
853 4HP 0.8714
854 DGL 0.8712
855 UFV 0.8710
856 7WA 0.8708
857 HQY 0.8706
858 MPD 0.8706
859 DEE 0.8704
860 BP1 0.8702
861 GAF 0.8700
862 SSN 0.8699
863 CTL 0.8697
864 9DA 0.8696
865 1SP 0.8695
866 DAL DAL 0.8694
867 1P7 0.8694
868 LRH 0.8690
869 2A9 0.8687
870 SOE 0.8687
871 XXG 0.8686
872 MSE 0.8686
873 HH8 0.8685
874 MSR 0.8684
875 4XH 0.8683
876 GTR 0.8682
877 SYM 0.8682
878 XQ0 0.8682
879 FLA 0.8678
880 NDH 0.8677
881 ES7 0.8677
882 GCU 0.8676
883 GLA 0.8675
884 SER 0.8674
885 ABA 0.8673
886 1SH 0.8671
887 DMJ 0.8671
888 ET2 0.8669
889 BHH 0.8668
890 EVA 0.8668
891 3DO 0.8667
892 ES4 0.8667
893 7W4 0.8667
894 5NI 0.8666
895 ACH 0.8666
896 FPK 0.8665
897 6X8 0.8664
898 3PP 0.8663
899 4XX 0.8663
900 9TY 0.8662
901 PM6 0.8659
902 4ZC 0.8659
903 QIC 0.8656
904 MAN 0.8656
905 DQA 0.8653
906 LYS 0.8653
907 5XC 0.8652
908 CEJ 0.8652
909 8GL 0.8651
910 DFU 0.8651
911 GXL 0.8648
912 SME 0.8647
913 C2N 0.8646
914 FA3 0.8646
915 7MH 0.8645
916 V55 0.8645
917 OMD 0.8645
918 4JO 0.8645
919 TMZ 0.8643
920 260 0.8643
921 NK1 0.8642
922 IUR 0.8641
923 DCY 0.8641
924 RIP 0.8639
925 CAQ 0.8637
926 HCI 0.8635
927 VGD 0.8633
928 FUC 0.8633
929 3YP 0.8633
930 2CH 0.8631
931 152 0.8631
932 36R 0.8629
933 SR1 0.8628
934 FBB 0.8628
935 PYG 0.8626
936 1WC 0.8625
937 Y8I 0.8623
938 0MK 0.8621
939 PRZ 0.8620
940 X6X 0.8619
941 FUL 0.8617
942 ADZ 0.8617
943 24T 0.8616
944 CLW 0.8615
945 J0Z 0.8615
946 HTS 0.8612
947 K2T 0.8610
948 32O 0.8606
949 4JC 0.8605
950 8WT 0.8605
951 KVP 0.8604
952 B09 0.8602
953 938 0.8601
954 9X6 0.8600
955 2FG 0.8600
956 6MH 0.8600
957 2H5 0.8597
958 HFA 0.8597
959 DHY 0.8595
960 PEZ 0.8594
961 M4S 0.8590
962 YHO 0.8590
963 DTU 0.8583
964 JIF 0.8580
965 EUG 0.8567
966 JA8 0.8564
967 T6C 0.8561
968 2EC 0.8561
969 ICB 0.8555
970 4PN 0.8551
971 5VM 0.8550
972 DBB 0.8550
973 SDD 0.8531
974 6TZ 0.8526
975 BMA 0.8525
976 LGC 0.8516
977 LZM 0.8514
978 NF3 0.8510
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3KFC; Ligand: 61X; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3kfc.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 3KFC; Ligand: 61X; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 3kfc.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 3KFC; Ligand: 61X; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 3kfc.bio2) has 42 residues
No: Leader PDB Ligand Sequence Similarity
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