Receptor
PDB id Resolution Class Description Source Keywords
2BX7 2.04 Å EC: 1.3.3.1 CRYSTAL STRUCTURE OF L. LACTIS DIHYDROOROTATE DEHYDROGENSE A COMPLEX WITH 3,5-DIHYDROXYBENZOATE LACTOCOCCUS LACTIS OXIDOREDUCTASE NUCLEOTIDE METABOLISM DIHYDROOROTATE DEHYDR
Ref.: INTERACTION OF BENZOATE PYRIMIDINE ANALOGUES WITH C DIHYDROOROTATE DEHYDROGENASE FROM LACTOCOCCUS LACTI BIOCHEMISTRY V. 46 5741 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
34D B:1313;
Valid;
none;
submit data
154.12 C7 H6 O4 c1c(c...
ACT A:1313;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
FMN A:1312;
B:1312;
Valid;
Valid;
none;
none;
submit data
456.344 C17 H21 N4 O9 P Cc1cc...
GOL A:1315;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
MG A:1314;
B:1314;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1OVD 2.25 Å EC: 1.3.3.1 THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDR IN COMPLEX WITH OROTATE LACTOCOCCUS LACTIS HOMODIMER ALPHA-BETA BARREL FLAVOPROTEIN OROTATE COMPLEXENZYME OXIDOREDUCTASE
Ref.: LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A M REVEAL IMPORTANT FACETS OF THE ENZYMATIC FUNCTION. J.BIOL.CHEM. V. 278 28812 2003
Members (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1JQX Kd = 95 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
2 1JQV Kd = 117 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
3 2DOR - ORO C5 H4 N2 O4 C1=C(NC(=O....
4 1DOR - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
5 1JRB Kd = 1450 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
6 1JUE - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
7 1OVD Kd = 7.6 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
8 1JRC Kd = 44 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
9 2BX7 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
10 2BSL Kd = 8 uM DHB C7 H6 O4 c1cc(c(cc1....
11 1JUB - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
70% Homology Family (21)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3C3N - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 2E6D - FUM C4 H4 O4 C(=C/C(=O)....
3 4WZH - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
4 1JQX Kd = 95 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
5 1JQV Kd = 117 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
6 2DOR - ORO C5 H4 N2 O4 C1=C(NC(=O....
7 1DOR - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
8 1JRB Kd = 1450 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
9 1JUE - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
10 1OVD Kd = 7.6 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
11 1JRC Kd = 44 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
12 2BX7 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
13 2BSL Kd = 8 uM DHB C7 H6 O4 c1cc(c(cc1....
14 1JUB - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
15 4EF8 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
16 3MJY Ki = 82.8 uM IJZ C5 H5 N3 O4 C1(=C(NC(=....
17 4EF9 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
18 3MHU Ki = 212.93 uM EJZ C5 H3 N3 O6 C1(=C(NC(=....
19 3TQ0 - FUM C4 H4 O4 C(=C/C(=O)....
20 2B4G - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
21 5XFV Kd = 0.000000012 uM FMN C17 H21 N4 O9 P Cc1cc2c(cc....
50% Homology Family (22)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3C3N - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 2E6D - FUM C4 H4 O4 C(=C/C(=O)....
3 4WZH - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
4 1JQX Kd = 95 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
5 1JQV Kd = 117 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
6 2DOR - ORO C5 H4 N2 O4 C1=C(NC(=O....
7 1DOR - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
8 1JRB Kd = 1450 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
9 1JUE - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
10 1OVD Kd = 7.6 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
11 1JRC Kd = 44 uM ORO C5 H4 N2 O4 C1=C(NC(=O....
12 2BX7 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
13 2BSL Kd = 8 uM DHB C7 H6 O4 c1cc(c(cc1....
14 1JUB - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
15 4EF8 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
16 3MJY Ki = 82.8 uM IJZ C5 H5 N3 O4 C1(=C(NC(=....
17 4EF9 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
18 3MHU Ki = 212.93 uM EJZ C5 H3 N3 O6 C1(=C(NC(=....
19 3TQ0 - FUM C4 H4 O4 C(=C/C(=O)....
20 2B4G - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
21 5XFV Kd = 0.000000012 uM FMN C17 H21 N4 O9 P Cc1cc2c(cc....
22 3OIX - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 34D; Similar ligands found: 10
No: Ligand ECFP6 Tc MDL keys Tc
1 34D 1 1
2 AW5 0.548387 0.8
3 3HB 0.4375 0.842105
4 GDE 0.433333 0.826087
5 5HN 0.424242 0.615385
6 E35 0.416667 0.76
7 13X 0.409091 0.842105
8 QSH 0.40625 0.64
9 FGZ 0.40625 0.64
10 PHB 0.4 0.842105
Ligand no: 2; Ligand: FMN; Similar ligands found: 18
No: Ligand ECFP6 Tc MDL keys Tc
1 FMN 1 1
2 RBF 0.75641 0.876712
3 9O9 0.574468 0.934211
4 RS3 0.571429 0.831169
5 FAD 0.543307 0.876543
6 FAS 0.543307 0.876543
7 FAE 0.539062 0.865854
8 UBG 0.534351 0.888889
9 5DD 0.475248 0.972603
10 LFN 0.475 0.643836
11 C3F 0.473684 0.74359
12 CF4 0.463918 0.734177
13 FAY 0.446043 0.864198
14 FNR 0.444444 0.909091
15 RFL 0.442857 0.845238
16 4LS 0.411215 0.875
17 1VY 0.406593 0.769231
18 DLZ 0.404494 0.782051
Similar Ligands (3D)
Ligand no: 1; Ligand: 34D; Similar ligands found: 989
No: Ligand Similarity coefficient
1 ORO 1.0000
2 D1X 0.9988
3 DOR 0.9985
4 OXC 0.9964
5 S76 0.9759
6 4CS 0.9729
7 UNC 0.9729
8 A13 0.9691
9 FOT 0.9689
10 HJP 0.9674
11 NMJ 0.9672
12 3NT 0.9670
13 IJZ 0.9666
14 WCE 0.9666
15 DHK 0.9665
16 2A7 0.9657
17 GAB 0.9637
18 OVV 0.9629
19 53C 0.9619
20 8GC 0.9615
21 FBU 0.9605
22 C2U 0.9605
23 BRT 0.9605
24 3AB 0.9603
25 3OC 0.9599
26 ZZ3 0.9596
27 2AL 0.9590
28 MJ2 0.9532
29 6OT 0.9527
30 DBH 0.9522
31 9MG 0.9522
32 BGC 0.9521
33 GUN 0.9515
34 1XN 0.9514
35 AS3 0.9506
36 EV0 0.9493
37 3HA 0.9486
38 AJ2 0.9483
39 PE0 0.9481
40 AZA 0.9481
41 KT7 0.9476
42 URC 0.9475
43 9DG 0.9475
44 4XV 0.9463
45 3BZ 0.9459
46 JBK 0.9454
47 3F0 0.9449
48 M6N 0.9447
49 7WR 0.9442
50 51R 0.9441
51 SKM 0.9441
52 4NC 0.9440
53 3MB 0.9439
54 DIU 0.9437
55 3IT 0.9435
56 3M0 0.9435
57 Q24 0.9432
58 BDP 0.9430
59 MUA 0.9429
60 Q6T 0.9426
61 GLC 0.9425
62 N5J 0.9424
63 1LM 0.9415
64 Q88 0.9415
65 M5K 0.9414
66 1LQ 0.9411
67 XAN 0.9409
68 1NP 0.9409
69 JBH 0.9409
70 AQO 0.9409
71 AZ8 0.9408
72 IGA 0.9406
73 P9P 0.9403
74 CHB 0.9401
75 7NI 0.9400
76 1SQ 0.9399
77 24W 0.9396
78 ES1 0.9393
79 GCU 0.9389
80 CFP 0.9388
81 GTQ 0.9387
82 J9T 0.9386
83 R8V 0.9386
84 AKH 0.9384
85 4XS 0.9382
86 J9W 0.9382
87 4HC 0.9381
88 5IQ 0.9381
89 5RG 0.9380
90 DHB 0.9377
91 FE DB1 0.9377
92 O72 0.9375
93 7MU 0.9374
94 141 0.9371
95 4YS 0.9370
96 JLZ 0.9367
97 CWM 0.9365
98 F12 0.9365
99 PZI 0.9364
100 INO 0.9363
101 6CS 0.9362
102 GTR 0.9361
103 5SG 0.9360
104 ES0 0.9360
105 DX4 0.9359
106 5M0 0.9358
107 NNO 0.9357
108 JPZ 0.9356
109 GYE 0.9356
110 4A3 0.9350
111 YH7 0.9350
112 II6 0.9348
113 A2F 0.9348
114 M1Q 0.9348
115 290 0.9347
116 5Q0 0.9346
117 QSB 0.9345
118 42C 0.9344
119 VNL 0.9339
120 MYJ 0.9338
121 FHB 0.9338
122 MEW 0.9334
123 HQY 0.9332
124 B55 0.9330
125 BOA 0.9330
126 8TX 0.9329
127 GCB 0.9326
128 G3F 0.9324
129 3ID 0.9324
130 QPR 0.9323
131 UFV 0.9319
132 BEZ 0.9318
133 SJ5 0.9318
134 DRL 0.9311
135 O2A 0.9308
136 7B4 0.9308
137 IPZ 0.9306
138 M1H 0.9306
139 HPA 0.9305
140 B2J 0.9304
141 A7W 0.9303
142 3HM 0.9303
143 93K 0.9302
144 7N0 0.9301
145 9TW 0.9297
146 R9S 0.9296
147 BEN 0.9296
148 BCP 0.9292
149 8S0 0.9291
150 M0Q 0.9287
151 IHB 0.9286
152 NCA 0.9284
153 4XH 0.9284
154 BTY 0.9279
155 AZG 0.9279
156 DQA 0.9278
157 JFJ 0.9277
158 6PC 0.9275
159 QBK 0.9274
160 GCS 0.9273
161 XCZ 0.9272
162 ADE 0.9271
163 NBZ 0.9270
164 M1E 0.9270
165 M0W 0.9270
166 GV9 0.9270
167 9TZ 0.9270
168 6GU 0.9269
169 5JQ 0.9269
170 KUF 0.9269
171 54G 0.9268
172 4ME 0.9267
173 D07 0.9266
174 PDC 0.9265
175 1XM 0.9262
176 10L 0.9262
177 FBW 0.9261
178 KIB 0.9261
179 6AP 0.9260
180 0W8 0.9259
181 NIO 0.9259
182 BAM 0.9259
183 1P3 0.9257
184 HH8 0.9257
185 BE2 0.9256
186 ADA 0.9254
187 EVA 0.9254
188 15L 0.9253
189 7VS 0.9253
190 495 0.9252
191 CWS 0.9251
192 75K 0.9249
193 2AK 0.9248
194 HHA 0.9248
195 PBC 0.9246
196 0P6 0.9246
197 F31 0.9243
198 GAL 0.9242
199 YCP 0.9242
200 FA3 0.9238
201 SAL 0.9237
202 069 0.9237
203 UNU 0.9236
204 MT0 0.9232
205 APZ 0.9230
206 5MK 0.9228
207 2D0 0.9228
208 3Z8 0.9226
209 PZA 0.9226
210 SVN 0.9225
211 9DA 0.9224
212 NCD 0.9223
213 2HO 0.9221
214 AIN 0.9220
215 9HX 0.9219
216 HLD 0.9218
217 4MU 0.9217
218 HLZ 0.9215
219 ADZ 0.9215
220 I3A 0.9214
221 AC0 0.9213
222 AZ9 0.9213
223 UAN 0.9212
224 LSA 0.9211
225 7WA 0.9210
226 OVM 0.9210
227 6MP 0.9209
228 K5W 0.9208
229 M1Z 0.9208
230 23A 0.9205
231 DIN 0.9203
232 4HM 0.9201
233 C2A 0.9200
234 8CM 0.9199
235 DMD 0.9196
236 JKZ 0.9193
237 2FG 0.9192
238 V55 0.9188
239 P3K 0.9186
240 XAZ 0.9186
241 12M 0.9183
242 MO8 0.9181
243 BP1 0.9180
244 0CU 0.9179
245 0FO 0.9177
246 HH5 0.9176
247 AX2 0.9175
248 1AL 0.9175
249 MRW 0.9173
250 NOJ 0.9171
251 HQD 0.9171
252 2ZX 0.9170
253 BTE 0.9170
254 5ZE 0.9169
255 1P7 0.9168
256 AHR 0.9168
257 7HP 0.9166
258 5JL 0.9165
259 KIA 0.9163
260 4M4 0.9163
261 5AN 0.9162
262 MAQ 0.9159
263 ES4 0.9159
264 6UA 0.9159
265 DBJ 0.9158
266 OTD 0.9157
267 SX1 0.9155
268 5WY 0.9154
269 DFB 0.9154
270 45L 0.9151
271 B60 0.9150
272 3AL 0.9150
273 6M4 0.9149
274 QIC 0.9148
275 0GZ 0.9148
276 PM6 0.9142
277 XQ0 0.9140
278 XX2 0.9140
279 4AA 0.9140
280 AX3 0.9138
281 SS1 0.9138
282 7HQ 0.9137
283 BR8 0.9136
284 4SV 0.9135
285 ERH 0.9133
286 JTH 0.9132
287 3FH 0.9132
288 8IG 0.9131
289 OW4 0.9130
290 IP0 0.9128
291 23J 0.9125
292 0N7 0.9125
293 F05 0.9124
294 6M9 0.9124
295 B62 0.9123
296 F0J 0.9122
297 TCZ 0.9122
298 QX4 0.9121
299 DQU 0.9120
300 KKN 0.9119
301 PHT 0.9119
302 ES6 0.9119
303 2PG 0.9117
304 XSP 0.9117
305 EUG 0.9117
306 QSC 0.9117
307 KFH 0.9114
308 261 0.9114
309 2DR 0.9114
310 8WO 0.9113
311 9EW 0.9109
312 FP1 0.9107
313 IFM 0.9106
314 DIE 0.9106
315 JBE 0.9104
316 HQJ 0.9104
317 3AY 0.9104
318 149 0.9104
319 FA6 0.9103
320 TWO 0.9102
321 IFP 0.9101
322 ICO 0.9099
323 XHP 0.9098
324 3Z7 0.9098
325 4SX 0.9098
326 GLA 0.9098
327 GIV 0.9098
328 DHS 0.9097
329 X0V 0.9097
330 GZL 0.9097
331 F81 0.9092
332 OTW 0.9092
333 KOJ 0.9091
334 G4D 0.9091
335 NFQ 0.9088
336 HZQ 0.9088
337 NTN 0.9088
338 ISZ 0.9087
339 EA1 0.9085
340 7MH 0.9082
341 4XR 0.9082
342 JIF 0.9080
343 BHO 0.9078
344 DNC 0.9078
345 VGL 0.9077
346 9KH 0.9075
347 LT2 0.9075
348 OMD 0.9074
349 SC2 0.9073
350 LGC 0.9071
351 M58 0.9071
352 CFI 0.9070
353 LZM 0.9070
354 KBB 0.9069
355 DBX 0.9069
356 0RW 0.9068
357 5RN 0.9068
358 VOH 0.9068
359 AY4 0.9068
360 HNQ 0.9064
361 J9Q 0.9064
362 QWN 0.9063
363 ISN 0.9063
364 67N 0.9062
365 97T 0.9060
366 3U4 0.9058
367 VXX 0.9058
368 LYL 0.9057
369 T6C 0.9057
370 2F6 0.9056
371 TZE 0.9055
372 HLR 0.9054
373 JKE 0.9054
374 7WV 0.9053
375 SXS 0.9053
376 42A 0.9053
377 CIT 0.9052
378 SYA 0.9052
379 SKA 0.9051
380 1GN 0.9051
381 4FH 0.9051
382 WDL 0.9050
383 FA0 0.9049
384 6VD 0.9049
385 QUZ 0.9049
386 CDV 0.9048
387 AGK 0.9048
388 AZF 0.9047
389 8WT 0.9047
390 LNR 0.9047
391 CN0 0.9047
392 5OB 0.9046
393 HQT 0.9046
394 FYU 0.9045
395 7W1 0.9044
396 6ME 0.9044
397 BNS 0.9044
398 1WD 0.9043
399 0W1 0.9043
400 2H5 0.9042
401 5NU 0.9041
402 G5V 0.9040
403 NID 0.9039
404 RSO 0.9039
405 R8S 0.9039
406 OXZ 0.9038
407 HXX 0.9038
408 2ZQ 0.9037
409 293 0.9036
410 HMH 0.9036
411 PRZ 0.9034
412 7WG 0.9033
413 60Q 0.9032
414 4Z4 0.9031
415 GAG 0.9030
416 NPY 0.9030
417 5QX 0.9027
418 SS2 0.9026
419 TRC 0.9025
420 44V 0.9024
421 35C 0.9022
422 DNF 0.9022
423 2A9 0.9021
424 EYK 0.9021
425 BZX 0.9021
426 ASO 0.9020
427 44W 0.9019
428 M2K 0.9019
429 KBG 0.9019
430 6TZ 0.9019
431 ASC 0.9019
432 ES7 0.9018
433 7W4 0.9016
434 GJS 0.9015
435 2LP 0.9015
436 AUD 0.9015
437 CCB 0.9013
438 UEG 0.9013
439 1F1 0.9012
440 EKZ 0.9011
441 HMU 0.9011
442 IV2 0.9011
443 RXA 0.9010
444 FBM 0.9010
445 DA4 0.9009
446 MVN 0.9009
447 3DM 0.9008
448 5WV 0.9008
449 OCH 0.9007
450 DOB 0.9006
451 L5V 0.9006
452 QXW 0.9005
453 VNJ 0.9004
454 KTA 0.9003
455 PD2 0.9003
456 BMA 0.9002
457 JR2 0.9001
458 8GK 0.8999
459 1DW 0.8998
460 NTM 0.8998
461 T9G 0.8997
462 TIU 0.8997
463 47J 0.8996
464 SHA 0.8995
465 E7Z 0.8995
466 EDR 0.8995
467 SHG 0.8994
468 HBD 0.8994
469 5CU 0.8994
470 2EC 0.8993
471 NQ 0.8992
472 QAS 0.8992
473 G6D 0.8991
474 M1A 0.8991
475 8XQ 0.8991
476 PFL 0.8991
477 GLT 0.8990
478 5WX 0.8990
479 7ZE 0.8988
480 SWD 0.8987
481 COU 0.8986
482 ZXD 0.8986
483 XQG 0.8985
484 AX7 0.8985
485 NIZ 0.8985
486 MBG 0.8984
487 FLC 0.8984
488 4M0 0.8984
489 YIO 0.8981
490 JZ3 0.8980
491 ZZT 0.8980
492 CXF 0.8980
493 INE 0.8980
494 FDB 0.8979
495 XYP 0.8978
496 NPO 0.8978
497 270 0.8977
498 GIF 0.8975
499 GBD 0.8975
500 0F9 0.8970
501 PXL 0.8970
502 BZ3 0.8970
503 QWW 0.8969
504 3SK 0.8969
505 TFU 0.8966
506 7ME 0.8966
507 14O 0.8966
508 1Y6 0.8966
509 GIO 0.8965
510 25W 0.8965
511 IT2 0.8964
512 OXQ 0.8964
513 2LY 0.8964
514 6XI 0.8963
515 H42 0.8962
516 TRA 0.8961
517 VK3 0.8961
518 M5N 0.8960
519 GJZ 0.8960
520 PFB 0.8958
521 QAT 0.8958
522 ONR 0.8955
523 SAF 0.8955
524 RM1 0.8955
525 YQA 0.8954
526 12B 0.8954
527 SWA 0.8954
528 8G0 0.8953
529 JBQ 0.8953
530 GM7 0.8952
531 ABV 0.8951
532 XM0 0.8950
533 NTZ 0.8950
534 PAB 0.8949
535 ZWZ 0.8949
536 GZ8 0.8948
537 GLY PRO 0.8947
538 AMC 0.8947
539 5B1 0.8947
540 KLW 0.8946
541 BHA 0.8946
542 2AQ 0.8945
543 FAN 0.8945
544 TBP 0.8944
545 Z5P 0.8944
546 ASP 0.8944
547 IPB 0.8943
548 LDP 0.8943
549 03V 0.8942
550 9PY 0.8942
551 G2H 0.8941
552 MWP 0.8941
553 5QY 0.8938
554 4ZC 0.8937
555 URF 0.8936
556 A29 0.8935
557 QX2 0.8934
558 JND 0.8934
559 BEA 0.8932
560 KJY 0.8931
561 MAN 0.8929
562 3WA 0.8929
563 NVU 0.8928
564 L99 0.8926
565 40E 0.8926
566 C2Y 0.8925
567 V6F 0.8925
568 3MA 0.8925
569 DEN 0.8924
570 ADK 0.8922
571 0HO 0.8922
572 C9E 0.8921
573 FEH 0.8921
574 ICT 0.8920
575 52C 0.8917
576 SVD 0.8917
577 X6X 0.8917
578 F9P 0.8916
579 QM1 0.8916
580 X0W 0.8916
581 5NI 0.8915
582 OVP 0.8914
583 FB2 0.8914
584 F60 0.8914
585 4JT 0.8913
586 PMB 0.8912
587 3XX 0.8912
588 GRE 0.8912
589 NK 0.8911
590 3MG 0.8910
591 5H1 0.8910
592 92P 0.8909
593 2K4 0.8909
594 6AI 0.8907
595 B53 0.8907
596 SOE 0.8906
597 RNS 0.8906
598 HY3 0.8905
599 ZZ8 0.8904
600 1X7 0.8904
601 EOL 0.8903
602 I1E 0.8903
603 HBX 0.8902
604 PYF 0.8902
605 K3Q 0.8902
606 FBV 0.8900
607 KYA 0.8900
608 AC6 0.8900
609 1DJ 0.8899
610 4FS 0.8899
611 IND 0.8898
612 329 0.8897
613 MCT 0.8895
614 AN0 0.8895
615 MLT 0.8894
616 HX3 0.8893
617 FRU 0.8892
618 FBG 0.8892
619 MXN 0.8892
620 4ZE 0.8891
621 3R6 0.8891
622 PQK 0.8889
623 FH2 0.8888
624 H7Y 0.8888
625 AEH 0.8888
626 GTL 0.8886
627 4P5 0.8886
628 NDM 0.8885
629 N7P 0.8885
630 GXL 0.8885
631 EQT 0.8884
632 FA1 0.8883
633 2MI 0.8883
634 PBZ 0.8883
635 LZ1 0.8882
636 MWM 0.8882
637 N3W 0.8881
638 SF9 0.8881
639 QY9 0.8878
640 EMZ 0.8877
641 OAA 0.8877
642 JAE 0.8873
643 TAG 0.8873
644 6M1 0.8872
645 GLY CYS 0.8871
646 G2F 0.8871
647 5MB 0.8871
648 PA1 0.8870
649 3NY 0.8868
650 60P 0.8868
651 R20 0.8868
652 BNT 0.8868
653 TEP 0.8867
654 BZI 0.8867
655 FUL 0.8865
656 EGR 0.8864
657 IDM 0.8864
658 6NT 0.8862
659 PHU 0.8862
660 2HU 0.8862
661 URQ 0.8862
662 MLE 0.8862
663 FDK 0.8861
664 5MI 0.8860
665 JFD 0.8859
666 SR1 0.8858
667 NXA 0.8857
668 3HP 0.8856
669 TDR 0.8856
670 P92 0.8856
671 ASN 0.8854
672 GAF 0.8853
673 IFL 0.8852
674 H4N 0.8850
675 XBZ 0.8850
676 IF7 0.8850
677 FB1 0.8849
678 2EH 0.8848
679 4HO 0.8846
680 BSX 0.8845
681 MZB 0.8845
682 PY7 0.8843
683 2YU 0.8843
684 5AC 0.8843
685 2ZM 0.8842
686 TM7 0.8841
687 ABN 0.8841
688 F5B 0.8840
689 GLU 0.8840
690 BZF 0.8838
691 BK9 0.8838
692 KYD 0.8837
693 0GY 0.8837
694 ES5 0.8835
695 WBU 0.8830
696 42J 0.8829
697 DAS 0.8829
698 JB5 0.8828
699 XXR 0.8827
700 MHK 0.8826
701 3DO 0.8826
702 M2H 0.8825
703 SOR 0.8825
704 A1U 0.8824
705 51F 0.8824
706 MPI 0.8824
707 LKA 0.8822
708 ABI 0.8822
709 82I 0.8820
710 92K 0.8819
711 DGJ 0.8819
712 2AC 0.8816
713 0HN 0.8816
714 GVH 0.8815
715 1MC 0.8815
716 KDF 0.8815
717 QOS 0.8813
718 43M 0.8813
719 DMJ 0.8812
720 34A 0.8811
721 XYD 0.8811
722 YSO 0.8811
723 4P0 0.8811
724 1P8 0.8809
725 OW7 0.8808
726 JZ4 0.8808
727 RMN 0.8807
728 282 0.8807
729 TPA 0.8807
730 4JJ 0.8807
731 P84 0.8807
732 6LW 0.8807
733 2MP 0.8806
734 TT4 0.8806
735 1LN 0.8805
736 ES9 0.8805
737 MZG 0.8804
738 URS 0.8803
739 LEU 0.8801
740 H76 0.8801
741 HT4 0.8801
742 CRS 0.8800
743 FK1 0.8799
744 CRN 0.8799
745 6F0 0.8798
746 TH0 0.8797
747 RIB 0.8794
748 NOY 0.8794
749 SYN 0.8793
750 NDH 0.8792
751 286 0.8791
752 GOG 0.8791
753 ICP 0.8790
754 PEZ 0.8787
755 BR9 0.8786
756 3CH 0.8781
757 RD4 0.8781
758 UFO 0.8780
759 0R1 0.8777
760 PAC 0.8777
761 173 0.8776
762 692 0.8776
763 0R0 0.8774
764 5XC 0.8774
765 463 0.8774
766 LMR 0.8773
767 FUF 0.8773
768 VGD 0.8772
769 11S 0.8770
770 3A9 0.8769
771 MFB 0.8767
772 RCO 0.8766
773 L3Q 0.8765
774 2TQ 0.8765
775 4H2 0.8765
776 5UC 0.8764
777 M4T 0.8763
778 7VJ 0.8763
779 MWJ 0.8762
780 6RQ 0.8761
781 CLW 0.8761
782 4CL 0.8761
783 URA 0.8760
784 ALL 0.8760
785 AKG 0.8758
786 CFA 0.8757
787 JZ2 0.8757
788 MR1 0.8757
789 284 0.8756
790 717 0.8755
791 HY1 0.8754
792 XXG 0.8752
793 PEA 0.8752
794 TH7 0.8751
795 APY 0.8750
796 GLN 0.8749
797 FUC 0.8748
798 PYJ 0.8747
799 CIG 0.8746
800 SYR 0.8746
801 NBE 0.8746
802 TM4 0.8745
803 27Y 0.8745
804 PYD 0.8743
805 SMN 0.8743
806 B3R 0.8742
807 6NI 0.8742
808 ES2 0.8740
809 WOO 0.8740
810 LT8 0.8739
811 A9O 0.8738
812 LFR 0.8738
813 LG3 0.8737
814 5JC 0.8737
815 1XA 0.8736
816 O7U 0.8735
817 6MH 0.8734
818 2MN 0.8734
819 RB5 0.8733
820 XYL 0.8733
821 CIZ 0.8731
822 B24 0.8731
823 DUB 0.8729
824 OHP 0.8728
825 R8A 0.8727
826 DEE 0.8726
827 M3T 0.8726
828 DYA 0.8725
829 ET2 0.8725
830 GP9 0.8724
831 CKU 0.8724
832 QUS 0.8723
833 57O 0.8723
834 5MH 0.8722
835 8W9 0.8722
836 ITN 0.8721
837 3SL 0.8716
838 HEW 0.8715
839 MS9 0.8715
840 A9P 0.8715
841 HIO 0.8714
842 AMG 0.8713
843 AH8 0.8712
844 PEP 0.8711
845 XIY 0.8711
846 HDH 0.8710
847 2CM 0.8710
848 PEL 0.8709
849 NCT 0.8709
850 HHQ 0.8705
851 R9Y 0.8705
852 M4E 0.8704
853 2MY 0.8703
854 KGK 0.8703
855 L7T 0.8702
856 BVF 0.8701
857 GVG 0.8701
858 23W 0.8701
859 BE7 0.8699
860 HKD 0.8698
861 39A 0.8698
862 P4B 0.8698
863 9RW 0.8696
864 CYT 0.8695
865 HGQ 0.8694
866 8NY 0.8694
867 271 0.8693
868 LG5 0.8692
869 FBT 0.8689
870 36R 0.8689
871 0LH 0.8687
872 LCN 0.8687
873 0V5 0.8687
874 JZ1 0.8682
875 26D 0.8681
876 GOX 0.8679
877 SYG 0.8678
878 FCR 0.8678
879 ENL 0.8678
880 8OZ 0.8678
881 5GU 0.8676
882 ZBT 0.8676
883 ZZ2 0.8676
884 2D3 0.8673
885 TTY 0.8670
886 4TU 0.8670
887 HBA 0.8669
888 MSN 0.8669
889 JA8 0.8669
890 285 0.8669
891 FQI 0.8663
892 ORN 0.8661
893 94N 0.8660
894 3CE 0.8660
895 XUL 0.8660
896 WOT 0.8660
897 Y8I 0.8660
898 PRO 0.8659
899 XBT 0.8658
900 4JO 0.8657
901 NGO 0.8656
902 8GF 0.8656
903 209 0.8655
904 MBD 0.8653
905 9CL 0.8652
906 RAT 0.8652
907 RM4 0.8651
908 PYG 0.8651
909 PIM 0.8650
910 4NG 0.8649
911 HA7 0.8649
912 TSS 0.8648
913 5NE 0.8647
914 XQI 0.8646
915 NIG 0.8645
916 RHU 0.8645
917 6R8 0.8643
918 FCB 0.8643
919 JZ9 0.8643
920 MRZ 0.8642
921 ODO 0.8642
922 FPK 0.8641
923 AOS 0.8639
924 SMV 0.8638
925 XQK 0.8637
926 95Z 0.8635
927 7D2 0.8635
928 GMN 0.8632
929 ROI 0.8630
930 3FA 0.8630
931 FBS 0.8628
932 1DV 0.8624
933 H33 0.8623
934 X09 0.8622
935 MFU 0.8622
936 TSU 0.8621
937 8NX 0.8620
938 ONL 0.8619
939 TLD 0.8619
940 SRT 0.8618
941 A09 0.8618
942 2FY 0.8617
943 HA5 0.8613
944 DIG 0.8613
945 1U1 0.8612
946 HDL 0.8611
947 VPR 0.8609
948 SLC 0.8608
949 6DP 0.8607
950 GLY LEU 0.8606
951 SAN 0.8604
952 CBF 0.8603
953 IDH 0.8600
954 1MR 0.8598
955 AOR 0.8596
956 RIP 0.8596
957 2C9 0.8595
958 DHY 0.8594
959 NBG 0.8593
960 JB8 0.8592
961 4AV 0.8591
962 4A5 0.8588
963 IAC 0.8586
964 BDF 0.8575
965 4JP 0.8575
966 SF6 0.8572
967 FLM 0.8568
968 4VP 0.8567
969 67X 0.8567
970 NLA 0.8566
971 H3M 0.8560
972 PKU 0.8559
973 F9Y 0.8558
974 8WZ 0.8558
975 2CG 0.8557
976 ICF 0.8556
977 OA3 0.8553
978 W8G 0.8552
979 TLA 0.8551
980 EXO 0.8545
981 2BG 0.8543
982 1M2 0.8543
983 DFU 0.8541
984 FPY 0.8539
985 QMP 0.8535
986 EJZ 0.8531
987 JYD 0.8529
988 CWJ 0.8526
989 DAL DAL 0.8523
Ligand no: 2; Ligand: FMN; Similar ligands found: 10
No: Ligand Similarity coefficient
1 7O6 0.9670
2 4X4 0.8996
3 4LU 0.8884
4 E2U 0.8865
5 HDF 0.8834
6 AFQ 0.8817
7 E2X 0.8805
8 E89 0.8698
9 1WJ 0.8673
10 FZZ 0.8606
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1OVD; Ligand: FMN; Similar sites found with APoc: 5
This union binding pocket(no: 1) in the query (biounit: 1ovd.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 1F76 FMN 40.5145
2 1F76 FMN 40.5145
3 1F76 FMN 40.5145
4 1F76 FMN 40.5145
5 1F76 ORO 40.5145
Pocket No.: 2; Query (leader) PDB : 1OVD; Ligand: FMN; Similar sites found with APoc: 13
This union binding pocket(no: 2) in the query (biounit: 1ovd.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 1F76 FMN 40.5145
2 1F76 FMN 40.5145
3 1F76 FMN 40.5145
4 1F76 FMN 40.5145
5 1F76 ORO 40.5145
6 1GTE FMN 42.4437
7 1GTE IUR 42.4437
8 1GTE FMN 42.4437
9 1GTE IUR 42.4437
10 1GTE IUR 42.4437
11 1GTE FMN 42.4437
12 1GTE FMN 42.4437
13 1GTE IUR 42.4437
Pocket No.: 3; Query (leader) PDB : 1OVD; Ligand: ORO; Similar sites found with APoc: 13
This union binding pocket(no: 3) in the query (biounit: 1ovd.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 1F76 FMN 40.5145
2 1F76 FMN 40.5145
3 1F76 FMN 40.5145
4 1F76 FMN 40.5145
5 1F76 ORO 40.5145
6 1GTE FMN 42.4437
7 1GTE IUR 42.4437
8 1GTE FMN 42.4437
9 1GTE IUR 42.4437
10 1GTE IUR 42.4437
11 1GTE FMN 42.4437
12 1GTE FMN 42.4437
13 1GTE IUR 42.4437
Pocket No.: 4; Query (leader) PDB : 1OVD; Ligand: ORO; Similar sites found with APoc: 5
This union binding pocket(no: 4) in the query (biounit: 1ovd.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 1F76 FMN 40.5145
2 1F76 FMN 40.5145
3 1F76 FMN 40.5145
4 1F76 FMN 40.5145
5 1F76 ORO 40.5145
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