Receptor
PDB id Resolution Class Description Source Keywords
2G9V 2.15 Å EC: 2.4.1.1 THE CRYSTAL STRUCTURE OF GLYCOGEN PHOSPHORYLASE IN COMPLEX W 4R,5R)-5-HYDROXYMETHYLPIPERIDINE-3,4-DIOL AND PHOSPHATE ORYCTOLAGUS CUNICULUS GLYCOGEN PHOSPHORYLASE CATALYTIC SITE RATIONAL INHIBITOR DTRANSFERASE
Ref.: IMINOSUGARS AS POTENTIAL INHIBITORS OF GLYCOGENOLYS STRUCTURAL INSIGHTS INTO THE MOLECULAR BASIS OF GLY PHOSPHORYLASE INHIBITION. J.MED.CHEM. V. 49 5687 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
IFM A:998;
 Valid;
 none;
 Ki = 5.2 uM
147.172 C6 H13 N O3 C1[C@...
PO4 A:996;
A:997;
 Invalid;
Invalid;
 none;
none;
 submit data
94.971 O4 P [O-]P...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2AMV 2.3 Å EC: 2.4.1.1 THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYL- DIHYDROPYRIDINE-DICARBOXYLIC ACID ORYCTOLAGUS CUNICULUS GLYCOGEN PHOSPHORYLASE GLYCOGEN METABOLISM DIABETES INHIBGLYCOSYLTRANSFERASE TRANSFERASE
Ref.: THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYLDIHYDROPYRIDINE-DICARBOXYLIC ACID COMPOUND, A POTENT INHIBITOR. STRUCTURE V. 5 1413 1997
Members (171)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3MRT ic50 = 200 uM 12E C13 H18 N4 O5 S c1cnccc1/C....
2 1AXR Ki = 540 uM HTP C7 H12 N3 O4 c1c2[n+]([....
3 1FTY - GL7 C9 H14 N2 O7 CN1C(=O)[C....
4 3MQF ic50 = 5.7 uM 20X C14 H18 F N3 O5 S c1cc(ccc1/....
5 3MS7 ic50 = 370 uM 22S C14 H18 Cl N3 O5 S c1ccc(c(c1....
6 4EKY Ki = 303 uM D1J C15 H20 N2 O7 CCCC#CC1=C....
7 1C50 ic50 = 334 nM CHI C23 H23 Cl F N3 O3 c1cc(ccc1C....
8 6F3R Ki = 1.19 uM CKZ C21 H21 N3 O5 c1ccc-2c(c....
9 5MCB Ki = 2.5 mM CGG C16 H18 O9 c1cc(c(cc1....
10 3L7D Ki = 6.55 mM DK5 C17 H18 F N3 O5 c1ccc(cc1)....
11 1WUY ic50 = 1.6 uM BN3 C18 H15 Cl3 N2 O5 c1cc(c(cc1....
12 2PRI Ki = 1.23 mM D6G C6 H13 O8 P C1[C@H]([C....
13 6Y5O Ki = 3.89 uM O9Z C15 H9 F O4 c1cc(ccc1C....
14 1NOK Ki = 700 uM NTZ C6 H10 N4 O4 C([C@@H]1[....
15 1WV0 ic50 = 2.9 uM BN4 C20 H20 Cl2 N2 O5 Cc1c(c(ccc....
16 5OWY - B0W C15 H17 N3 O7 c1cc(ccc1c....
17 1E1Y ic50 = 2.5 uM CPB C21 H20 Cl N O5 C[N@]1CC[C....
18 1B4D Ki = 15.6 uM CRA C9 H16 N2 O8 COC(=O)N[C....
19 6R0I Ki = 9.7 uM JNB C19 H21 N O6 c1ccc(cc1)....
20 4MI6 Ki = 48.68 uM 26V C20 H29 N O6 c1cc2c(cc1....
21 2QRM Ki = 92.5 uM M09 C14 H18 N2 O8 c1cc(ccc1C....
22 3G2I Ki = 13.7 uM RUG C9 H15 N3 O6 c1c(nnn1[C....
23 1XL0 Ki = 145.2 uM OX2 C9 H14 N2 O6 Cc1nnc(o1)....
24 5LRE - KS3 C18 H19 N3 O5 c1ccc2cc(c....
25 1GPY Kd ~ 25 uM G6P C6 H13 O9 P C([C@@H]1[....
26 2GJ4 ic50 = 319 nM 2TH C16 H13 Cl N2 O2 S c1ccc2c(c1....
27 2GPA - GLC C6 H12 O6 C([C@@H]1[....
28 1P4G Ki = 1.8 mM CGF C7 H14 N4 O6 C([C@@H]1[....
29 1Z6Q ic50 = 74 nM 195 C28 H18 N4 O11 c1cc(cc(c1....
30 3NC4 ic50 = 26.6 uM 26O C14 H19 N3 O6 S c1ccc(c(c1....
31 2AMV Ki = 1.6 nM BIN C20 H21 Cl N O6 CC[n+]1c(c....
32 3MS4 ic50 = 524.3 uM 21N C15 H18 F3 N3 O5 S c1cc(ccc1/....
33 3L79 Ki = 3.46 mM DKX C10 H13 F N2 O6 C1=CN(C(=O....
34 2QRH Ki = 19.6 uM M08 C14 H17 N O6 c1ccc(cc1)....
35 1WW3 Ki = 75 uM NTF C8 H12 F3 N O6 C([C@@H]1[....
36 3MTD ic50 = 340.5 uM 25E C14 H19 N3 O6 S c1cc(ccc1/....
37 1FU4 - GL9 C10 H15 N3 O8 CC(=O)NN1C....
38 1P2B - GLC GLC GLC GLC GLC n/a n/a
39 2FFR - DL6 C8 H14 N4 O6 C([C@@H]1[....
40 1WUT ic50 = 1.9 uM BN2 C21 H21 Cl3 N2 O5 c1ccc(c(c1....
41 2G9U ic50 = 0.84 uM G27 C15 H23 N O3 c1ccc(cc1)....
42 6F3U Ki = 11.5 uM CNK C18 H19 N3 O5 c1ccc2c(c1....
43 4CTN Ki = 10 uM M8P C19 H18 N2 O7 S c1ccc2cc(c....
44 2GM9 ic50 = 41 nM 3TH C16 H12 Cl N3 O2 S c1ccc2c(c1....
45 6S52 Ki = 162.3 uM KVN C13 H16 N4 O5 c1ccc(cc1)....
46 1NOI Ki = 700 uM NTZ C6 H10 N4 O4 C([C@@H]1[....
47 4MHO Ki = 8.25 uM 26M C20 H23 N O7 c1ccc(cc1)....
48 3MT9 ic50 = 25.7 uM 18O C14 H18 N4 O7 S c1cc(ccc1/....
49 4CTM Ki = 24 uM MIF C8 H12 N2 O6 S C([C@@H]1[....
50 3SYR Ki = 7.9 uM GPK C10 H13 F N2 O7 C1=C(C(=O)....
51 6S4O Ki = 4.58 uM KV5 C19 H20 N2 O5 c1ccc2cc(c....
52 3G2N - OAK C13 H17 N O6 c1ccc(cc1)....
53 3NP7 ic50 = 95 uM Z15 C12 H15 Cl O7 c1c(c(cc(c....
54 2F3Q Ki = 0.22 mM 6GP C9 H15 N O8 COC(=O)C(=....
55 4YUA Ki = 13.4 uM REF C14 H6 O8 c1c2c-3c(c....
56 2IEI ic50 = 0.121 uM FRX C20 H19 Cl N4 O4 S c1ccc2c(c1....
57 4EL0 Ki = 32.4 uM D1K C15 H20 N2 O7 CCCC1=CC2=....
58 1WW2 Ki = 32 uM NBG C8 H15 N O6 CC(=O)N[C@....
59 4EL5 Ki = 4.7 uM D1M C12 H14 N2 O7 C#CC1=CN(C....
60 4MI3 Ki = 75.29 uM 26R C19 H29 N O6 C[C@H](Cc1....
61 3L7C Ki = 3.67 mM DK4 C10 H12 F2 N2 O6 C1=C(C(=O)....
62 6S4R Ki = 26.2 uM KVH C19 H19 N O5 S c1ccc2cc(c....
63 1FTQ - IMP C10 H13 N4 O8 P c1nc2c(n1[....
64 3T3E Ki = 1.02 uM GPQ C10 H13 Cl N2 O7 C1=C(C(=O)....
65 3GPB Kd = 9.5 mM G1P C6 H13 O9 P C([C@@H]1[....
66 2QRG Ki = 6.6 uM M07 C15 H19 N O7 COc1ccc(cc....
67 3L7B Ki = 4.01 mM DKZ C10 H14 F N3 O5 C1=CN(C(=O....
68 3AMV Ki = 10.8 nM BIN C20 H21 Cl N O6 CC[n+]1c(c....
69 5OX1 Ki = 1.95 uM B1K C15 H19 N3 O6 COc1ccc(cc....
70 2PRJ Ki = 32 uM NBG C8 H15 N O6 CC(=O)N[C@....
71 1C8L ic50 = 6.9 nM BIN C20 H21 Cl N O6 CC[n+]1c(c....
72 1XC7 Ki = 5.1 mM GL6 C8 H18 N O8 P COP(=O)(N[....
73 3MSC ic50 = 484.2 uM 24S C14 H18 N4 O7 S c1ccc(c(c1....
74 1FU7 - CR1 C8 H15 N O7 COC(=O)N[C....
75 4MRA ic50 = 33.5 uM QUE C15 H10 O7 c1cc(c(cc1....
76 5LRC Ki = 7 uM 73E C14 H17 N3 O5 c1ccc(cc1)....
77 2G9R ic50 = 0.84 uM G27 C15 H23 N O3 c1ccc(cc1)....
78 1FTW - GL5 C8 H12 N2 O8 C([C@@H]1[....
79 4MIC Ki = 4.98 uM 26Y C18 H25 N O6 CC(C)c1ccc....
80 1Z62 Ki = 16 uM IAA C18 H13 N3 O4 C1C=CC=C2C....
81 2SKD - IMP C10 H13 N4 O8 P c1nc2c(n1[....
82 5GPB - GPM C7 H15 O8 P C([C@@H]1[....
83 2G9V Ki = 5.2 uM IFM C6 H13 N O3 C1[C@@H]([....
84 3MT7 ic50 = 93.2 uM 16O C14 H18 Br N3 O5 S c1cc(ccc1/....
85 5OWZ Ki = 111 uM B0Z C15 H16 F3 N3 O5 c1cc(ccc1c....
86 2QRQ Ki = 7.9 uM S13 C15 H21 N O6 Cc1ccc(cc1....
87 5LRF Ki = 0.41 uM KS3 C18 H19 N3 O5 c1ccc2cc(c....
88 1A8I Ki = 3 uM GLS C8 H12 N2 O7 C([C@@H]1[....
89 8GPB Kd = 250 uM AMP C10 H14 N5 O7 P c1nc(c2c(n....
90 6F3J Ki = 4.42 uM CKQ C21 H21 N3 O7 c1cc(ccc1c....
91 3SYM Ki = 27.1 uM GP0 C11 H15 F N2 O8 C1=C(C(=O)....
92 1GG8 Ki = 1 mM GLG C7 H13 N O6 C([C@@H]1[....
93 3T3G Ki = 3.27 uM GPU C10 H13 Br N2 O7 C1=C(C(=O)....
94 5LRD Ki = 1.7 uM KS2 C15 H19 N3 O5 Cc1ccc(cc1....
95 3NP9 ic50 = 39.8 uM Z2T C13 H17 Cl O7 COc1cc(c(c....
96 1Z8D - AMP C10 H14 N5 O7 P c1nc(c2c(n....
97 6QA6 Ki = 2.11 uM HT8 C18 H18 N2 O6 c1ccc2cc(c....
98 3G2L Ki = 135.9 uM LEW C18 H19 N3 O5 c1ccc2c(c1....
99 4MI9 Ki = 376.87 uM 26W C18 H27 N O6 CCc1ccc(cc....
100 3G2J - 9GP C8 H15 N O7 C([C@@H]1[....
101 1P4J Ki = 0.88 mM CBF C7 H13 N O7 C([C@@H]1[....
102 1GGN Ki = 3.1 uM GLS C8 H12 N2 O7 C([C@@H]1[....
103 3L7A Ki = 46.42 uM DKY C17 H18 F N3 O6 c1ccc(cc1)....
104 1KTI Ki = 370 uM AZC C9 H16 N2 O7 CC(=O)NC(=....
105 2GPB Ki = 2 mM GLC C6 H12 O6 C([C@@H]1[....
106 6F3S Ki = 2.38 uM CKW C20 H21 N3 O5 c1ccc(cc1)....
107 2F3P Ki = 0.71 mM 4GP C8 H13 N O8 C([C@@H]1[....
108 5OX3 Ki = 2.9 uM B1N C14 H17 N3 O6 c1cc(ccc1c....
109 6S4P Ki = 158 uM KVE C19 H19 N O5 S c1ccc2cc(c....
110 1LWN - GLC C6 H12 O6 C([C@@H]1[....
111 1P29 - GLC GLC GLC GLC GLC n/a n/a
112 1XKX Ki = 8.6 uM IMK C14 H18 N2 O5 Cc1ccc2c(c....
113 2SKE - IMP C10 H13 N4 O8 P c1nc2c(n1[....
114 1FS4 - CRA C9 H16 N2 O8 COC(=O)N[C....
115 1GFZ Ki ~ 0.15 mM CFF C8 H10 N4 O2 Cn1cnc2c1C....
116 3S0J ic50 = 169.9 uM Z15 C12 H15 Cl O7 c1c(c(cc(c....
117 6S4K Ki = 310 uM KVW C15 H17 N O5 S c1ccc(cc1)....
118 1WV1 ic50 = 2.8 uM BN5 C20 H20 Cl2 N2 O5 Cc1c(cccc1....
119 6S51 Ki = 326 uM KVQ C15 H17 N O5 S c1ccc(cc1)....
120 6F3L Ki = 5.05 uM CJW C19 H19 N3 O7 c1cc(cc2c1....
121 6Y5C Ki = 21.36 uM O9T C16 H12 O4 Cc1ccc(cc1....
122 6R0H Ki = 56.1 uM JN2 C19 H20 F N O6 c1cc(cc(c1....
123 2F3S Ki = 0.92 mM 7GP C10 H17 N O8 CCOC(=O)C(....
124 6Y55 Ki = 2.23 uM O9Q C16 H12 O4 Cc1cccc(c1....
125 3T3D Ki = 12.39 uM CJB C10 H14 N2 O7 C1=CN(C(=O....
126 1K08 Ki = 4.6 uM BZD C14 H18 N2 O7 c1ccc(cc1)....
127 6QA8 Ki = 9 uM HTE C14 H16 N2 O6 c1ccc(cc1)....
128 5JTT Ki = 0.28 uM 6MY C15 H18 N2 O5 c1ccc(cc1)....
129 3G2H Ki = 151.3 uM KOT C14 H17 N3 O5 c1ccc(cc1)....
130 1C8K ic50 = 1 uM CPB C21 H20 Cl N O5 C[N@]1CC[C....
131 3MTA ic50 = 50.4 uM 22O C14 H18 Br N3 O5 S c1cc(cc(c1....
132 2QN1 - 0AS C30 H48 O5 C[C@@H]1CC....
133 5OX0 Ki = 33.5 uM B1H C14 H17 N4 O7 c1cc(ccc1c....
134 3MRV ic50 = 180 uM 16F C14 H19 N3 O6 S c1cc(cc(c1....
135 2PYD Ki = 1.7 mM GLC C6 H12 O6 C([C@@H]1[....
136 1P4H Ki = 0.31 mM CR6 C9 H16 N2 O7 CC(=O)N[C@....
137 4GPB - GFP C6 H12 F O8 P C([C@@H]1[....
138 1FU8 - CR6 C9 H16 N2 O7 CC(=O)N[C@....
139 5MEM Ki = 71 nM 7LS C23 H22 N4 O7 c1ccc2c(c1....
140 2SKC - GLC C6 H12 O6 C([C@@H]1[....
141 3MT8 ic50 = 28.3 uM 17T C14 H18 Cl N3 O5 S c1cc(ccc1/....
142 1LWO - GLC C6 H12 O6 C([C@@H]1[....
143 1K06 Ki = 4.6 uM BZD C14 H18 N2 O7 c1ccc(cc1)....
144 4YI3 Ki = 4.95 uM 4D0 C22 H26 N2 O7 c1ccc(cc1)....
145 5JTU Ki = 0.031 uM 6NE C19 H20 N2 O5 c1ccc2cc(c....
146 4MHS Ki = 5.14 uM 26Q C21 H23 N O6 c1ccc(cc1)....
147 5OX4 Ki = 0.67 uM B1W C14 H18 N4 O5 c1cc(ccc1c....
148 1XL1 Ki = 76 uM TH1 C14 H17 N O5 S Cc1ccc2c(c....
149 1H5U ic50 = 178 nM CHI C23 H23 Cl F N3 O3 c1cc(ccc1C....
150 2QRP Ki = 0.63 uM S06 C18 H21 N O6 c1ccc2cc(c....
151 3NPA ic50 = 136.4 uM Z57 C12 H15 Br O7 c1c(c(cc(c....
152 1P2G Ki = 7.4 mM GLC GLC GLC GLC GLC GLC GLC GLC n/a n/a
153 4Z5X Ki = 1730 uM GDE C7 H6 O5 c1c(cc(c(c....
154 4YI5 Ki = 2.53 uM 4D1 C19 H26 N2 O7 CC(C)c1ccc....
155 1NOJ Ki = 700 uM NTZ C6 H10 N4 O4 C([C@@H]1[....
156 2F3U Ki = 1.41 mM 8GP C11 H18 N2 O7 C1CC1NC(=O....
157 1UZU Ki = 13.8 uM INR C16 H10 N2 O5 S c1ccc2c(c1....
158 4CTO Ki = 9 uM M7C C15 H16 N2 O7 S c1ccc(cc1)....
159 3G2K Ki = 16.1 uM SKY C18 H19 N3 O5 c1ccc2cc(c....
160 6QA7 Ki = 13 uM HTW C18 H18 N2 O6 c1ccc2c(c1....
161 1Z6P ic50 = 0.9 uM 194 C21 H14 N2 O8 c1ccc(c(c1....
162 2PYI Ki = 179 uM DL8 C16 H20 N4 O6 c1ccc(cc1)....
163 3MRX ic50 = 406.5 uM 17S C15 H21 N3 O6 S COc1ccc(cc....
164 2IEG ic50 = 0.135 uM FRY C18 H15 Cl N4 O3 S c1ccc2c(c1....
165 2G9Q ic50 = 0.84 uM 1AB C5 H11 N O3 C1[C@H]([C....
166 3MTB ic50 = 23.2 uM 23V C14 H18 Cl N3 O5 S c1cc(cc(c1....
167 2OFF Ki = 0.46 uM OFF C23 H20 O10 c1cc(ccc1C....
168 1P2D - GLC GLC n/a n/a
169 1HLF Ki = 2.3 uM GL4 C8 H12 N2 O6 S C([C@@H]1[....
170 3MS2 ic50 = 192.4 uM 18S C15 H21 N3 O5 S Cc1ccc(cc1....
171 6S4H Ki = 68.6 uM KUQ C15 H18 N2 O5 c1ccc(cc1)....
70% Homology Family (185)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3MRT ic50 = 200 uM 12E C13 H18 N4 O5 S c1cnccc1/C....
2 1AXR Ki = 540 uM HTP C7 H12 N3 O4 c1c2[n+]([....
3 1FTY - GL7 C9 H14 N2 O7 CN1C(=O)[C....
4 3MQF ic50 = 5.7 uM 20X C14 H18 F N3 O5 S c1cc(ccc1/....
5 3MS7 ic50 = 370 uM 22S C14 H18 Cl N3 O5 S c1ccc(c(c1....
6 4EKY Ki = 303 uM D1J C15 H20 N2 O7 CCCC#CC1=C....
7 1C50 ic50 = 334 nM CHI C23 H23 Cl F N3 O3 c1cc(ccc1C....
8 6F3R Ki = 1.19 uM CKZ C21 H21 N3 O5 c1ccc-2c(c....
9 5MCB Ki = 2.5 mM CGG C16 H18 O9 c1cc(c(cc1....
10 3L7D Ki = 6.55 mM DK5 C17 H18 F N3 O5 c1ccc(cc1)....
11 1WUY ic50 = 1.6 uM BN3 C18 H15 Cl3 N2 O5 c1cc(c(cc1....
12 2PRI Ki = 1.23 mM D6G C6 H13 O8 P C1[C@H]([C....
13 6Y5O Ki = 3.89 uM O9Z C15 H9 F O4 c1cc(ccc1C....
14 1NOK Ki = 700 uM NTZ C6 H10 N4 O4 C([C@@H]1[....
15 1WV0 ic50 = 2.9 uM BN4 C20 H20 Cl2 N2 O5 Cc1c(c(ccc....
16 5OWY - B0W C15 H17 N3 O7 c1cc(ccc1c....
17 1E1Y ic50 = 2.5 uM CPB C21 H20 Cl N O5 C[N@]1CC[C....
18 1B4D Ki = 15.6 uM CRA C9 H16 N2 O8 COC(=O)N[C....
19 6R0I Ki = 9.7 uM JNB C19 H21 N O6 c1ccc(cc1)....
20 4MI6 Ki = 48.68 uM 26V C20 H29 N O6 c1cc2c(cc1....
21 2QRM Ki = 92.5 uM M09 C14 H18 N2 O8 c1cc(ccc1C....
22 3G2I Ki = 13.7 uM RUG C9 H15 N3 O6 c1c(nnn1[C....
23 1XL0 Ki = 145.2 uM OX2 C9 H14 N2 O6 Cc1nnc(o1)....
24 5LRE - KS3 C18 H19 N3 O5 c1ccc2cc(c....
25 1GPY Kd ~ 25 uM G6P C6 H13 O9 P C([C@@H]1[....
26 2GJ4 ic50 = 319 nM 2TH C16 H13 Cl N2 O2 S c1ccc2c(c1....
27 2GPA - GLC C6 H12 O6 C([C@@H]1[....
28 1P4G Ki = 1.8 mM CGF C7 H14 N4 O6 C([C@@H]1[....
29 1Z6Q ic50 = 74 nM 195 C28 H18 N4 O11 c1cc(cc(c1....
30 3NC4 ic50 = 26.6 uM 26O C14 H19 N3 O6 S c1ccc(c(c1....
31 2AMV Ki = 1.6 nM BIN C20 H21 Cl N O6 CC[n+]1c(c....
32 3MS4 ic50 = 524.3 uM 21N C15 H18 F3 N3 O5 S c1cc(ccc1/....
33 3L79 Ki = 3.46 mM DKX C10 H13 F N2 O6 C1=CN(C(=O....
34 2QRH Ki = 19.6 uM M08 C14 H17 N O6 c1ccc(cc1)....
35 1WW3 Ki = 75 uM NTF C8 H12 F3 N O6 C([C@@H]1[....
36 3MTD ic50 = 340.5 uM 25E C14 H19 N3 O6 S c1cc(ccc1/....
37 1FU4 - GL9 C10 H15 N3 O8 CC(=O)NN1C....
38 1P2B - GLC GLC GLC GLC GLC n/a n/a
39 2FFR - DL6 C8 H14 N4 O6 C([C@@H]1[....
40 1WUT ic50 = 1.9 uM BN2 C21 H21 Cl3 N2 O5 c1ccc(c(c1....
41 2G9U ic50 = 0.84 uM G27 C15 H23 N O3 c1ccc(cc1)....
42 6F3U Ki = 11.5 uM CNK C18 H19 N3 O5 c1ccc2c(c1....
43 4CTN Ki = 10 uM M8P C19 H18 N2 O7 S c1ccc2cc(c....
44 2GM9 ic50 = 41 nM 3TH C16 H12 Cl N3 O2 S c1ccc2c(c1....
45 6S52 Ki = 162.3 uM KVN C13 H16 N4 O5 c1ccc(cc1)....
46 1NOI Ki = 700 uM NTZ C6 H10 N4 O4 C([C@@H]1[....
47 4MHO Ki = 8.25 uM 26M C20 H23 N O7 c1ccc(cc1)....
48 3MT9 ic50 = 25.7 uM 18O C14 H18 N4 O7 S c1cc(ccc1/....
49 4CTM Ki = 24 uM MIF C8 H12 N2 O6 S C([C@@H]1[....
50 3SYR Ki = 7.9 uM GPK C10 H13 F N2 O7 C1=C(C(=O)....
51 6S4O Ki = 4.58 uM KV5 C19 H20 N2 O5 c1ccc2cc(c....
52 3G2N - OAK C13 H17 N O6 c1ccc(cc1)....
53 3NP7 ic50 = 95 uM Z15 C12 H15 Cl O7 c1c(c(cc(c....
54 2F3Q Ki = 0.22 mM 6GP C9 H15 N O8 COC(=O)C(=....
55 4YUA Ki = 13.4 uM REF C14 H6 O8 c1c2c-3c(c....
56 2IEI ic50 = 0.121 uM FRX C20 H19 Cl N4 O4 S c1ccc2c(c1....
57 4EL0 Ki = 32.4 uM D1K C15 H20 N2 O7 CCCC1=CC2=....
58 1WW2 Ki = 32 uM NBG C8 H15 N O6 CC(=O)N[C@....
59 4EL5 Ki = 4.7 uM D1M C12 H14 N2 O7 C#CC1=CN(C....
60 4MI3 Ki = 75.29 uM 26R C19 H29 N O6 C[C@H](Cc1....
61 3L7C Ki = 3.67 mM DK4 C10 H12 F2 N2 O6 C1=C(C(=O)....
62 6S4R Ki = 26.2 uM KVH C19 H19 N O5 S c1ccc2cc(c....
63 1FTQ - IMP C10 H13 N4 O8 P c1nc2c(n1[....
64 3T3E Ki = 1.02 uM GPQ C10 H13 Cl N2 O7 C1=C(C(=O)....
65 3GPB Kd = 9.5 mM G1P C6 H13 O9 P C([C@@H]1[....
66 2QRG Ki = 6.6 uM M07 C15 H19 N O7 COc1ccc(cc....
67 3L7B Ki = 4.01 mM DKZ C10 H14 F N3 O5 C1=CN(C(=O....
68 3AMV Ki = 10.8 nM BIN C20 H21 Cl N O6 CC[n+]1c(c....
69 5OX1 Ki = 1.95 uM B1K C15 H19 N3 O6 COc1ccc(cc....
70 2PRJ Ki = 32 uM NBG C8 H15 N O6 CC(=O)N[C@....
71 1C8L ic50 = 6.9 nM BIN C20 H21 Cl N O6 CC[n+]1c(c....
72 1XC7 Ki = 5.1 mM GL6 C8 H18 N O8 P COP(=O)(N[....
73 3MSC ic50 = 484.2 uM 24S C14 H18 N4 O7 S c1ccc(c(c1....
74 1FU7 - CR1 C8 H15 N O7 COC(=O)N[C....
75 4MRA ic50 = 33.5 uM QUE C15 H10 O7 c1cc(c(cc1....
76 5LRC Ki = 7 uM 73E C14 H17 N3 O5 c1ccc(cc1)....
77 2G9R ic50 = 0.84 uM G27 C15 H23 N O3 c1ccc(cc1)....
78 1FTW - GL5 C8 H12 N2 O8 C([C@@H]1[....
79 4MIC Ki = 4.98 uM 26Y C18 H25 N O6 CC(C)c1ccc....
80 1Z62 Ki = 16 uM IAA C18 H13 N3 O4 C1C=CC=C2C....
81 2SKD - IMP C10 H13 N4 O8 P c1nc2c(n1[....
82 5GPB - GPM C7 H15 O8 P C([C@@H]1[....
83 2G9V Ki = 5.2 uM IFM C6 H13 N O3 C1[C@@H]([....
84 3MT7 ic50 = 93.2 uM 16O C14 H18 Br N3 O5 S c1cc(ccc1/....
85 5OWZ Ki = 111 uM B0Z C15 H16 F3 N3 O5 c1cc(ccc1c....
86 2QRQ Ki = 7.9 uM S13 C15 H21 N O6 Cc1ccc(cc1....
87 5LRF Ki = 0.41 uM KS3 C18 H19 N3 O5 c1ccc2cc(c....
88 1A8I Ki = 3 uM GLS C8 H12 N2 O7 C([C@@H]1[....
89 8GPB Kd = 250 uM AMP C10 H14 N5 O7 P c1nc(c2c(n....
90 6F3J Ki = 4.42 uM CKQ C21 H21 N3 O7 c1cc(ccc1c....
91 3SYM Ki = 27.1 uM GP0 C11 H15 F N2 O8 C1=C(C(=O)....
92 1GG8 Ki = 1 mM GLG C7 H13 N O6 C([C@@H]1[....
93 3T3G Ki = 3.27 uM GPU C10 H13 Br N2 O7 C1=C(C(=O)....
94 5LRD Ki = 1.7 uM KS2 C15 H19 N3 O5 Cc1ccc(cc1....
95 3NP9 ic50 = 39.8 uM Z2T C13 H17 Cl O7 COc1cc(c(c....
96 1Z8D - AMP C10 H14 N5 O7 P c1nc(c2c(n....
97 6QA6 Ki = 2.11 uM HT8 C18 H18 N2 O6 c1ccc2cc(c....
98 3G2L Ki = 135.9 uM LEW C18 H19 N3 O5 c1ccc2c(c1....
99 4MI9 Ki = 376.87 uM 26W C18 H27 N O6 CCc1ccc(cc....
100 3G2J - 9GP C8 H15 N O7 C([C@@H]1[....
101 1P4J Ki = 0.88 mM CBF C7 H13 N O7 C([C@@H]1[....
102 1GGN Ki = 3.1 uM GLS C8 H12 N2 O7 C([C@@H]1[....
103 3L7A Ki = 46.42 uM DKY C17 H18 F N3 O6 c1ccc(cc1)....
104 1KTI Ki = 370 uM AZC C9 H16 N2 O7 CC(=O)NC(=....
105 2GPB Ki = 2 mM GLC C6 H12 O6 C([C@@H]1[....
106 6F3S Ki = 2.38 uM CKW C20 H21 N3 O5 c1ccc(cc1)....
107 2F3P Ki = 0.71 mM 4GP C8 H13 N O8 C([C@@H]1[....
108 5OX3 Ki = 2.9 uM B1N C14 H17 N3 O6 c1cc(ccc1c....
109 6S4P Ki = 158 uM KVE C19 H19 N O5 S c1ccc2cc(c....
110 1LWN - GLC C6 H12 O6 C([C@@H]1[....
111 1P29 - GLC GLC GLC GLC GLC n/a n/a
112 1XKX Ki = 8.6 uM IMK C14 H18 N2 O5 Cc1ccc2c(c....
113 2SKE - IMP C10 H13 N4 O8 P c1nc2c(n1[....
114 1FS4 - CRA C9 H16 N2 O8 COC(=O)N[C....
115 1GFZ Ki ~ 0.15 mM CFF C8 H10 N4 O2 Cn1cnc2c1C....
116 3S0J ic50 = 169.9 uM Z15 C12 H15 Cl O7 c1c(c(cc(c....
117 6S4K Ki = 310 uM KVW C15 H17 N O5 S c1ccc(cc1)....
118 1WV1 ic50 = 2.8 uM BN5 C20 H20 Cl2 N2 O5 Cc1c(cccc1....
119 6S51 Ki = 326 uM KVQ C15 H17 N O5 S c1ccc(cc1)....
120 6F3L Ki = 5.05 uM CJW C19 H19 N3 O7 c1cc(cc2c1....
121 6Y5C Ki = 21.36 uM O9T C16 H12 O4 Cc1ccc(cc1....
122 6R0H Ki = 56.1 uM JN2 C19 H20 F N O6 c1cc(cc(c1....
123 2F3S Ki = 0.92 mM 7GP C10 H17 N O8 CCOC(=O)C(....
124 6Y55 Ki = 2.23 uM O9Q C16 H12 O4 Cc1cccc(c1....
125 3T3D Ki = 12.39 uM CJB C10 H14 N2 O7 C1=CN(C(=O....
126 1K08 Ki = 4.6 uM BZD C14 H18 N2 O7 c1ccc(cc1)....
127 6QA8 Ki = 9 uM HTE C14 H16 N2 O6 c1ccc(cc1)....
128 5JTT Ki = 0.28 uM 6MY C15 H18 N2 O5 c1ccc(cc1)....
129 3G2H Ki = 151.3 uM KOT C14 H17 N3 O5 c1ccc(cc1)....
130 1C8K ic50 = 1 uM CPB C21 H20 Cl N O5 C[N@]1CC[C....
131 3MTA ic50 = 50.4 uM 22O C14 H18 Br N3 O5 S c1cc(cc(c1....
132 2QN1 - 0AS C30 H48 O5 C[C@@H]1CC....
133 5OX0 Ki = 33.5 uM B1H C14 H17 N4 O7 c1cc(ccc1c....
134 3MRV ic50 = 180 uM 16F C14 H19 N3 O6 S c1cc(cc(c1....
135 2PYD Ki = 1.7 mM GLC C6 H12 O6 C([C@@H]1[....
136 1P4H Ki = 0.31 mM CR6 C9 H16 N2 O7 CC(=O)N[C@....
137 4GPB - GFP C6 H12 F O8 P C([C@@H]1[....
138 1FU8 - CR6 C9 H16 N2 O7 CC(=O)N[C@....
139 5MEM Ki = 71 nM 7LS C23 H22 N4 O7 c1ccc2c(c1....
140 2SKC - GLC C6 H12 O6 C([C@@H]1[....
141 3MT8 ic50 = 28.3 uM 17T C14 H18 Cl N3 O5 S c1cc(ccc1/....
142 1LWO - GLC C6 H12 O6 C([C@@H]1[....
143 1K06 Ki = 4.6 uM BZD C14 H18 N2 O7 c1ccc(cc1)....
144 4YI3 Ki = 4.95 uM 4D0 C22 H26 N2 O7 c1ccc(cc1)....
145 5JTU Ki = 0.031 uM 6NE C19 H20 N2 O5 c1ccc2cc(c....
146 4MHS Ki = 5.14 uM 26Q C21 H23 N O6 c1ccc(cc1)....
147 5OX4 Ki = 0.67 uM B1W C14 H18 N4 O5 c1cc(ccc1c....
148 1XL1 Ki = 76 uM TH1 C14 H17 N O5 S Cc1ccc2c(c....
149 1H5U ic50 = 178 nM CHI C23 H23 Cl F N3 O3 c1cc(ccc1C....
150 2QRP Ki = 0.63 uM S06 C18 H21 N O6 c1ccc2cc(c....
151 3NPA ic50 = 136.4 uM Z57 C12 H15 Br O7 c1c(c(cc(c....
152 1P2G Ki = 7.4 mM GLC GLC GLC GLC GLC GLC GLC GLC n/a n/a
153 4Z5X Ki = 1730 uM GDE C7 H6 O5 c1c(cc(c(c....
154 4YI5 Ki = 2.53 uM 4D1 C19 H26 N2 O7 CC(C)c1ccc....
155 1NOJ Ki = 700 uM NTZ C6 H10 N4 O4 C([C@@H]1[....
156 2F3U Ki = 1.41 mM 8GP C11 H18 N2 O7 C1CC1NC(=O....
157 1UZU Ki = 13.8 uM INR C16 H10 N2 O5 S c1ccc2c(c1....
158 4CTO Ki = 9 uM M7C C15 H16 N2 O7 S c1ccc(cc1)....
159 3G2K Ki = 16.1 uM SKY C18 H19 N3 O5 c1ccc2cc(c....
160 6QA7 Ki = 13 uM HTW C18 H18 N2 O6 c1ccc2c(c1....
161 1Z6P ic50 = 0.9 uM 194 C21 H14 N2 O8 c1ccc(c(c1....
162 2PYI Ki = 179 uM DL8 C16 H20 N4 O6 c1ccc(cc1)....
163 3MRX ic50 = 406.5 uM 17S C15 H21 N3 O6 S COc1ccc(cc....
164 2IEG ic50 = 0.135 uM FRY C18 H15 Cl N4 O3 S c1ccc2c(c1....
165 2G9Q ic50 = 0.84 uM 1AB C5 H11 N O3 C1[C@H]([C....
166 3MTB ic50 = 23.2 uM 23V C14 H18 Cl N3 O5 S c1cc(cc(c1....
167 2OFF Ki = 0.46 uM OFF C23 H20 O10 c1cc(ccc1C....
168 1P2D - GLC GLC n/a n/a
169 1HLF Ki = 2.3 uM GL4 C8 H12 N2 O6 S C([C@@H]1[....
170 3MS2 ic50 = 192.4 uM 18S C15 H21 N3 O5 S Cc1ccc(cc1....
171 6S4H Ki = 68.6 uM KUQ C15 H18 N2 O5 c1ccc(cc1)....
172 1L5R ic50 = 0.145 uM 700 C22 H20 Cl N3 O4 c1ccc(cc1)....
173 1EM6 ic50 = 6 nM CP4 C24 H24 Cl2 N4 O4 c1cc2c(cc1....
174 1L5Q ic50 = 0.145 uM 700 C22 H20 Cl N3 O4 c1ccc(cc1)....
175 1EXV ic50 = 45 nM 700 C22 H20 Cl N3 O4 c1ccc(cc1)....
176 1L7X ic50 = 0.145 uM 700 C22 H20 Cl N3 O4 c1ccc(cc1)....
177 3DDS ic50 = 506 nM 26B C29 H35 N3 O5 Cc1cc(c(c(....
178 1FC0 - NBG C8 H15 N O6 CC(=O)N[C@....
179 3CEM Kd = 24 nM AVD C23 H12 Cl2 F2 N2 O5 c1ccc(c(c1....
180 2ATI ic50 = 23 nM IHU C15 H12 Cl F N2 O4 COc1ccc(cc....
181 1L5S ic50 = 0.145 uM 700 C22 H20 Cl N3 O4 c1ccc(cc1)....
182 1FA9 - GLC C6 H12 O6 C([C@@H]1[....
183 1XOI ic50 = 0.057 uM 288 C18 H24 Cl N3 O3 c1cc2c(cc1....
184 3DDW ic50 = 1067 nM 055 C27 H22 Cl N3 O4 Cc1cccc(c1....
185 2ZB2 ic50 = 0.9 uM A46 C17 H15 Cl N2 O3 c1cc(ccc1[....
50% Homology Family (192)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3MRT ic50 = 200 uM 12E C13 H18 N4 O5 S c1cnccc1/C....
2 1AXR Ki = 540 uM HTP C7 H12 N3 O4 c1c2[n+]([....
3 1FTY - GL7 C9 H14 N2 O7 CN1C(=O)[C....
4 3MQF ic50 = 5.7 uM 20X C14 H18 F N3 O5 S c1cc(ccc1/....
5 3MS7 ic50 = 370 uM 22S C14 H18 Cl N3 O5 S c1ccc(c(c1....
6 4EKY Ki = 303 uM D1J C15 H20 N2 O7 CCCC#CC1=C....
7 1C50 ic50 = 334 nM CHI C23 H23 Cl F N3 O3 c1cc(ccc1C....
8 6F3R Ki = 1.19 uM CKZ C21 H21 N3 O5 c1ccc-2c(c....
9 5MCB Ki = 2.5 mM CGG C16 H18 O9 c1cc(c(cc1....
10 3L7D Ki = 6.55 mM DK5 C17 H18 F N3 O5 c1ccc(cc1)....
11 1WUY ic50 = 1.6 uM BN3 C18 H15 Cl3 N2 O5 c1cc(c(cc1....
12 2PRI Ki = 1.23 mM D6G C6 H13 O8 P C1[C@H]([C....
13 6Y5O Ki = 3.89 uM O9Z C15 H9 F O4 c1cc(ccc1C....
14 1NOK Ki = 700 uM NTZ C6 H10 N4 O4 C([C@@H]1[....
15 1WV0 ic50 = 2.9 uM BN4 C20 H20 Cl2 N2 O5 Cc1c(c(ccc....
16 5OWY - B0W C15 H17 N3 O7 c1cc(ccc1c....
17 1E1Y ic50 = 2.5 uM CPB C21 H20 Cl N O5 C[N@]1CC[C....
18 1B4D Ki = 15.6 uM CRA C9 H16 N2 O8 COC(=O)N[C....
19 6R0I Ki = 9.7 uM JNB C19 H21 N O6 c1ccc(cc1)....
20 4MI6 Ki = 48.68 uM 26V C20 H29 N O6 c1cc2c(cc1....
21 2QRM Ki = 92.5 uM M09 C14 H18 N2 O8 c1cc(ccc1C....
22 3G2I Ki = 13.7 uM RUG C9 H15 N3 O6 c1c(nnn1[C....
23 1XL0 Ki = 145.2 uM OX2 C9 H14 N2 O6 Cc1nnc(o1)....
24 5LRE - KS3 C18 H19 N3 O5 c1ccc2cc(c....
25 1GPY Kd ~ 25 uM G6P C6 H13 O9 P C([C@@H]1[....
26 2GJ4 ic50 = 319 nM 2TH C16 H13 Cl N2 O2 S c1ccc2c(c1....
27 2GPA - GLC C6 H12 O6 C([C@@H]1[....
28 1P4G Ki = 1.8 mM CGF C7 H14 N4 O6 C([C@@H]1[....
29 1Z6Q ic50 = 74 nM 195 C28 H18 N4 O11 c1cc(cc(c1....
30 3NC4 ic50 = 26.6 uM 26O C14 H19 N3 O6 S c1ccc(c(c1....
31 2AMV Ki = 1.6 nM BIN C20 H21 Cl N O6 CC[n+]1c(c....
32 3MS4 ic50 = 524.3 uM 21N C15 H18 F3 N3 O5 S c1cc(ccc1/....
33 3L79 Ki = 3.46 mM DKX C10 H13 F N2 O6 C1=CN(C(=O....
34 2QRH Ki = 19.6 uM M08 C14 H17 N O6 c1ccc(cc1)....
35 1WW3 Ki = 75 uM NTF C8 H12 F3 N O6 C([C@@H]1[....
36 3MTD ic50 = 340.5 uM 25E C14 H19 N3 O6 S c1cc(ccc1/....
37 1FU4 - GL9 C10 H15 N3 O8 CC(=O)NN1C....
38 1P2B - GLC GLC GLC GLC GLC n/a n/a
39 2FFR - DL6 C8 H14 N4 O6 C([C@@H]1[....
40 1WUT ic50 = 1.9 uM BN2 C21 H21 Cl3 N2 O5 c1ccc(c(c1....
41 2G9U ic50 = 0.84 uM G27 C15 H23 N O3 c1ccc(cc1)....
42 6F3U Ki = 11.5 uM CNK C18 H19 N3 O5 c1ccc2c(c1....
43 4CTN Ki = 10 uM M8P C19 H18 N2 O7 S c1ccc2cc(c....
44 2GM9 ic50 = 41 nM 3TH C16 H12 Cl N3 O2 S c1ccc2c(c1....
45 6S52 Ki = 162.3 uM KVN C13 H16 N4 O5 c1ccc(cc1)....
46 1NOI Ki = 700 uM NTZ C6 H10 N4 O4 C([C@@H]1[....
47 4MHO Ki = 8.25 uM 26M C20 H23 N O7 c1ccc(cc1)....
48 3MT9 ic50 = 25.7 uM 18O C14 H18 N4 O7 S c1cc(ccc1/....
49 4CTM Ki = 24 uM MIF C8 H12 N2 O6 S C([C@@H]1[....
50 3SYR Ki = 7.9 uM GPK C10 H13 F N2 O7 C1=C(C(=O)....
51 6S4O Ki = 4.58 uM KV5 C19 H20 N2 O5 c1ccc2cc(c....
52 3G2N - OAK C13 H17 N O6 c1ccc(cc1)....
53 3NP7 ic50 = 95 uM Z15 C12 H15 Cl O7 c1c(c(cc(c....
54 2F3Q Ki = 0.22 mM 6GP C9 H15 N O8 COC(=O)C(=....
55 4YUA Ki = 13.4 uM REF C14 H6 O8 c1c2c-3c(c....
56 2IEI ic50 = 0.121 uM FRX C20 H19 Cl N4 O4 S c1ccc2c(c1....
57 4EL0 Ki = 32.4 uM D1K C15 H20 N2 O7 CCCC1=CC2=....
58 1WW2 Ki = 32 uM NBG C8 H15 N O6 CC(=O)N[C@....
59 4EL5 Ki = 4.7 uM D1M C12 H14 N2 O7 C#CC1=CN(C....
60 4MI3 Ki = 75.29 uM 26R C19 H29 N O6 C[C@H](Cc1....
61 3L7C Ki = 3.67 mM DK4 C10 H12 F2 N2 O6 C1=C(C(=O)....
62 6S4R Ki = 26.2 uM KVH C19 H19 N O5 S c1ccc2cc(c....
63 1FTQ - IMP C10 H13 N4 O8 P c1nc2c(n1[....
64 3T3E Ki = 1.02 uM GPQ C10 H13 Cl N2 O7 C1=C(C(=O)....
65 3GPB Kd = 9.5 mM G1P C6 H13 O9 P C([C@@H]1[....
66 2QRG Ki = 6.6 uM M07 C15 H19 N O7 COc1ccc(cc....
67 3L7B Ki = 4.01 mM DKZ C10 H14 F N3 O5 C1=CN(C(=O....
68 3AMV Ki = 10.8 nM BIN C20 H21 Cl N O6 CC[n+]1c(c....
69 5OX1 Ki = 1.95 uM B1K C15 H19 N3 O6 COc1ccc(cc....
70 2PRJ Ki = 32 uM NBG C8 H15 N O6 CC(=O)N[C@....
71 1C8L ic50 = 6.9 nM BIN C20 H21 Cl N O6 CC[n+]1c(c....
72 1XC7 Ki = 5.1 mM GL6 C8 H18 N O8 P COP(=O)(N[....
73 3MSC ic50 = 484.2 uM 24S C14 H18 N4 O7 S c1ccc(c(c1....
74 1FU7 - CR1 C8 H15 N O7 COC(=O)N[C....
75 4MRA ic50 = 33.5 uM QUE C15 H10 O7 c1cc(c(cc1....
76 5LRC Ki = 7 uM 73E C14 H17 N3 O5 c1ccc(cc1)....
77 2G9R ic50 = 0.84 uM G27 C15 H23 N O3 c1ccc(cc1)....
78 1FTW - GL5 C8 H12 N2 O8 C([C@@H]1[....
79 4MIC Ki = 4.98 uM 26Y C18 H25 N O6 CC(C)c1ccc....
80 1Z62 Ki = 16 uM IAA C18 H13 N3 O4 C1C=CC=C2C....
81 2SKD - IMP C10 H13 N4 O8 P c1nc2c(n1[....
82 5GPB - GPM C7 H15 O8 P C([C@@H]1[....
83 2G9V Ki = 5.2 uM IFM C6 H13 N O3 C1[C@@H]([....
84 3MT7 ic50 = 93.2 uM 16O C14 H18 Br N3 O5 S c1cc(ccc1/....
85 5OWZ Ki = 111 uM B0Z C15 H16 F3 N3 O5 c1cc(ccc1c....
86 2QRQ Ki = 7.9 uM S13 C15 H21 N O6 Cc1ccc(cc1....
87 5LRF Ki = 0.41 uM KS3 C18 H19 N3 O5 c1ccc2cc(c....
88 1A8I Ki = 3 uM GLS C8 H12 N2 O7 C([C@@H]1[....
89 8GPB Kd = 250 uM AMP C10 H14 N5 O7 P c1nc(c2c(n....
90 6F3J Ki = 4.42 uM CKQ C21 H21 N3 O7 c1cc(ccc1c....
91 3SYM Ki = 27.1 uM GP0 C11 H15 F N2 O8 C1=C(C(=O)....
92 1GG8 Ki = 1 mM GLG C7 H13 N O6 C([C@@H]1[....
93 3T3G Ki = 3.27 uM GPU C10 H13 Br N2 O7 C1=C(C(=O)....
94 5LRD Ki = 1.7 uM KS2 C15 H19 N3 O5 Cc1ccc(cc1....
95 3NP9 ic50 = 39.8 uM Z2T C13 H17 Cl O7 COc1cc(c(c....
96 1Z8D - AMP C10 H14 N5 O7 P c1nc(c2c(n....
97 6QA6 Ki = 2.11 uM HT8 C18 H18 N2 O6 c1ccc2cc(c....
98 3G2L Ki = 135.9 uM LEW C18 H19 N3 O5 c1ccc2c(c1....
99 4MI9 Ki = 376.87 uM 26W C18 H27 N O6 CCc1ccc(cc....
100 3G2J - 9GP C8 H15 N O7 C([C@@H]1[....
101 1P4J Ki = 0.88 mM CBF C7 H13 N O7 C([C@@H]1[....
102 1GGN Ki = 3.1 uM GLS C8 H12 N2 O7 C([C@@H]1[....
103 3L7A Ki = 46.42 uM DKY C17 H18 F N3 O6 c1ccc(cc1)....
104 1KTI Ki = 370 uM AZC C9 H16 N2 O7 CC(=O)NC(=....
105 2GPB Ki = 2 mM GLC C6 H12 O6 C([C@@H]1[....
106 6F3S Ki = 2.38 uM CKW C20 H21 N3 O5 c1ccc(cc1)....
107 2F3P Ki = 0.71 mM 4GP C8 H13 N O8 C([C@@H]1[....
108 5OX3 Ki = 2.9 uM B1N C14 H17 N3 O6 c1cc(ccc1c....
109 6S4P Ki = 158 uM KVE C19 H19 N O5 S c1ccc2cc(c....
110 1LWN - GLC C6 H12 O6 C([C@@H]1[....
111 1P29 - GLC GLC GLC GLC GLC n/a n/a
112 1XKX Ki = 8.6 uM IMK C14 H18 N2 O5 Cc1ccc2c(c....
113 2SKE - IMP C10 H13 N4 O8 P c1nc2c(n1[....
114 1FS4 - CRA C9 H16 N2 O8 COC(=O)N[C....
115 1GFZ Ki ~ 0.15 mM CFF C8 H10 N4 O2 Cn1cnc2c1C....
116 3S0J ic50 = 169.9 uM Z15 C12 H15 Cl O7 c1c(c(cc(c....
117 6S4K Ki = 310 uM KVW C15 H17 N O5 S c1ccc(cc1)....
118 1WV1 ic50 = 2.8 uM BN5 C20 H20 Cl2 N2 O5 Cc1c(cccc1....
119 6S51 Ki = 326 uM KVQ C15 H17 N O5 S c1ccc(cc1)....
120 6F3L Ki = 5.05 uM CJW C19 H19 N3 O7 c1cc(cc2c1....
121 6Y5C Ki = 21.36 uM O9T C16 H12 O4 Cc1ccc(cc1....
122 6R0H Ki = 56.1 uM JN2 C19 H20 F N O6 c1cc(cc(c1....
123 2F3S Ki = 0.92 mM 7GP C10 H17 N O8 CCOC(=O)C(....
124 6Y55 Ki = 2.23 uM O9Q C16 H12 O4 Cc1cccc(c1....
125 3T3D Ki = 12.39 uM CJB C10 H14 N2 O7 C1=CN(C(=O....
126 1K08 Ki = 4.6 uM BZD C14 H18 N2 O7 c1ccc(cc1)....
127 6QA8 Ki = 9 uM HTE C14 H16 N2 O6 c1ccc(cc1)....
128 5JTT Ki = 0.28 uM 6MY C15 H18 N2 O5 c1ccc(cc1)....
129 3G2H Ki = 151.3 uM KOT C14 H17 N3 O5 c1ccc(cc1)....
130 1C8K ic50 = 1 uM CPB C21 H20 Cl N O5 C[N@]1CC[C....
131 3MTA ic50 = 50.4 uM 22O C14 H18 Br N3 O5 S c1cc(cc(c1....
132 2QN1 - 0AS C30 H48 O5 C[C@@H]1CC....
133 5OX0 Ki = 33.5 uM B1H C14 H17 N4 O7 c1cc(ccc1c....
134 3MRV ic50 = 180 uM 16F C14 H19 N3 O6 S c1cc(cc(c1....
135 2PYD Ki = 1.7 mM GLC C6 H12 O6 C([C@@H]1[....
136 1P4H Ki = 0.31 mM CR6 C9 H16 N2 O7 CC(=O)N[C@....
137 4GPB - GFP C6 H12 F O8 P C([C@@H]1[....
138 1FU8 - CR6 C9 H16 N2 O7 CC(=O)N[C@....
139 5MEM Ki = 71 nM 7LS C23 H22 N4 O7 c1ccc2c(c1....
140 2SKC - GLC C6 H12 O6 C([C@@H]1[....
141 3MT8 ic50 = 28.3 uM 17T C14 H18 Cl N3 O5 S c1cc(ccc1/....
142 1LWO - GLC C6 H12 O6 C([C@@H]1[....
143 1K06 Ki = 4.6 uM BZD C14 H18 N2 O7 c1ccc(cc1)....
144 4YI3 Ki = 4.95 uM 4D0 C22 H26 N2 O7 c1ccc(cc1)....
145 5JTU Ki = 0.031 uM 6NE C19 H20 N2 O5 c1ccc2cc(c....
146 4MHS Ki = 5.14 uM 26Q C21 H23 N O6 c1ccc(cc1)....
147 5OX4 Ki = 0.67 uM B1W C14 H18 N4 O5 c1cc(ccc1c....
148 1XL1 Ki = 76 uM TH1 C14 H17 N O5 S Cc1ccc2c(c....
149 1H5U ic50 = 178 nM CHI C23 H23 Cl F N3 O3 c1cc(ccc1C....
150 2QRP Ki = 0.63 uM S06 C18 H21 N O6 c1ccc2cc(c....
151 3NPA ic50 = 136.4 uM Z57 C12 H15 Br O7 c1c(c(cc(c....
152 1P2G Ki = 7.4 mM GLC GLC GLC GLC GLC GLC GLC GLC n/a n/a
153 4Z5X Ki = 1730 uM GDE C7 H6 O5 c1c(cc(c(c....
154 4YI5 Ki = 2.53 uM 4D1 C19 H26 N2 O7 CC(C)c1ccc....
155 1NOJ Ki = 700 uM NTZ C6 H10 N4 O4 C([C@@H]1[....
156 2F3U Ki = 1.41 mM 8GP C11 H18 N2 O7 C1CC1NC(=O....
157 1UZU Ki = 13.8 uM INR C16 H10 N2 O5 S c1ccc2c(c1....
158 4CTO Ki = 9 uM M7C C15 H16 N2 O7 S c1ccc(cc1)....
159 3G2K Ki = 16.1 uM SKY C18 H19 N3 O5 c1ccc2cc(c....
160 6QA7 Ki = 13 uM HTW C18 H18 N2 O6 c1ccc2c(c1....
161 1Z6P ic50 = 0.9 uM 194 C21 H14 N2 O8 c1ccc(c(c1....
162 2PYI Ki = 179 uM DL8 C16 H20 N4 O6 c1ccc(cc1)....
163 3MRX ic50 = 406.5 uM 17S C15 H21 N3 O6 S COc1ccc(cc....
164 2IEG ic50 = 0.135 uM FRY C18 H15 Cl N4 O3 S c1ccc2c(c1....
165 2G9Q ic50 = 0.84 uM 1AB C5 H11 N O3 C1[C@H]([C....
166 3MTB ic50 = 23.2 uM 23V C14 H18 Cl N3 O5 S c1cc(cc(c1....
167 2OFF Ki = 0.46 uM OFF C23 H20 O10 c1cc(ccc1C....
168 1P2D - GLC GLC n/a n/a
169 1HLF Ki = 2.3 uM GL4 C8 H12 N2 O6 S C([C@@H]1[....
170 3MS2 ic50 = 192.4 uM 18S C15 H21 N3 O5 S Cc1ccc(cc1....
171 6S4H Ki = 68.6 uM KUQ C15 H18 N2 O5 c1ccc(cc1)....
172 2AV6 - BGC GLC GLC GLC GLC n/a n/a
173 1L6I - GLC GLC GLC GLC GLC n/a n/a
174 1L5W - GLC GLC GLC GLC n/a n/a
175 2AW3 - BGC GLC GLC GLC GLC n/a n/a
176 1QM5 Ki = 1.5 uM GLC GLC GLC SGC PO4 GLC n/a n/a
177 1L5V - G1P C6 H13 O9 P C([C@@H]1[....
178 2AZD - BGC GLC GLC GLC n/a n/a
179 1L5R ic50 = 0.145 uM 700 C22 H20 Cl N3 O4 c1ccc(cc1)....
180 1EM6 ic50 = 6 nM CP4 C24 H24 Cl2 N4 O4 c1cc2c(cc1....
181 1L5Q ic50 = 0.145 uM 700 C22 H20 Cl N3 O4 c1ccc(cc1)....
182 1EXV ic50 = 45 nM 700 C22 H20 Cl N3 O4 c1ccc(cc1)....
183 1L7X ic50 = 0.145 uM 700 C22 H20 Cl N3 O4 c1ccc(cc1)....
184 3DDS ic50 = 506 nM 26B C29 H35 N3 O5 Cc1cc(c(c(....
185 1FC0 - NBG C8 H15 N O6 CC(=O)N[C@....
186 3CEM Kd = 24 nM AVD C23 H12 Cl2 F2 N2 O5 c1ccc(c(c1....
187 2ATI ic50 = 23 nM IHU C15 H12 Cl F N2 O4 COc1ccc(cc....
188 1L5S ic50 = 0.145 uM 700 C22 H20 Cl N3 O4 c1ccc(cc1)....
189 1FA9 - GLC C6 H12 O6 C([C@@H]1[....
190 1XOI ic50 = 0.057 uM 288 C18 H24 Cl N3 O3 c1cc2c(cc1....
191 3DDW ic50 = 1067 nM 055 C27 H22 Cl N3 O4 Cc1cccc(c1....
192 2ZB2 ic50 = 0.9 uM A46 C17 H15 Cl N2 O3 c1cc(ccc1[....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: IFM; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 GIF 1 1
2 IFM 1 1
3 3RK 0.464286 0.815789
4 7K2 0.403846 0.837209
Similar Ligands (3D)
Ligand no: 1; Ligand: IFM; Similar ligands found: 1237
No: Ligand Similarity coefficient
1 OXZ 1.0000
2 AZF 1.0000
3 DFB 1.0000
4 MLI 1.0000
5 PYG 0.9853
6 DBH 0.9849
7 23A 0.9844
8 3HA 0.9835
9 3M0 0.9829
10 F81 0.9825
11 JZ3 0.9824
12 3DM 0.9808
13 3F0 0.9807
14 FYU 0.9788
15 MBD 0.9786
16 NOJ 0.9781
17 AHR 0.9775
18 P3K 0.9768
19 BTE 0.9762
20 LYL 0.9758
21 2CM 0.9755
22 2MY 0.9751
23 2C9 0.9737
24 LCN 0.9737
25 NK 0.9735
26 GLC 0.9733
27 G2F 0.9725
28 DMJ 0.9723
29 GMN 0.9722
30 ASO 0.9719
31 1AB 0.9713
32 SJ5 0.9709
33 HPA 0.9704
34 XYS 0.9700
35 MAN 0.9699
36 6MH 0.9696
37 DUB 0.9693
38 0R0 0.9691
39 3FA 0.9687
40 R8A 0.9687
41 TM4 0.9684
42 FLM 0.9683
43 IFL 0.9683
44 XYP 0.9682
45 MNM 0.9671
46 URF 0.9671
47 FFP 0.9668
48 NOY 0.9665
49 DIE 0.9665
50 LXC 0.9660
51 BE2 0.9657
52 FE DB1 0.9656
53 R2B 0.9651
54 3CE 0.9650
55 286 0.9648
56 261 0.9646
57 HBA 0.9641
58 FP1 0.9634
59 BGC 0.9633
60 WBU 0.9626
61 SAL 0.9624
62 AGK 0.9623
63 3XX 0.9617
64 8H8 0.9614
65 3MC 0.9612
66 3MH 0.9610
67 94N 0.9606
68 HHA 0.9602
69 1LQ 0.9601
70 HGQ 0.9597
71 ZZT 0.9594
72 F05 0.9592
73 JZ1 0.9591
74 2XX 0.9589
75 ADE 0.9585
76 3IT 0.9585
77 GRE 0.9571
78 IJZ 0.9569
79 RIB 0.9563
80 Q88 0.9560
81 9DG 0.9560
82 64K 0.9558
83 B57 0.9557
84 CRS 0.9555
85 7B4 0.9553
86 SYN 0.9548
87 C2A 0.9541
88 260 0.9539
89 GAB 0.9538
90 7HP 0.9537
91 1LN 0.9532
92 6UA 0.9531
93 4VP 0.9529
94 1XX 0.9526
95 HXX 0.9526
96 3U4 0.9525
97 T6C 0.9523
98 3NT 0.9523
99 GLF 0.9522
100 6F0 0.9522
101 HMU 0.9521
102 ES6 0.9519
103 ARB 0.9515
104 HBX 0.9512
105 GUN 0.9506
106 53C 0.9504
107 7MH 0.9504
108 BSX 0.9500
109 FOT 0.9500
110 BZX 0.9500
111 XAN 0.9498
112 I3A 0.9495
113 URA 0.9493
114 GAL 0.9488
115 3HB 0.9482
116 PRY 0.9481
117 LGC 0.9478
118 3SK 0.9477
119 OVV 0.9477
120 JZ4 0.9476
121 BDF 0.9476
122 PA1 0.9474
123 BMA 0.9471
124 3Z7 0.9470
125 AFR 0.9466
126 KOJ 0.9465
127 26D 0.9465
128 4AA 0.9464
129 NEQ 0.9463
130 K5W 0.9462
131 KP6 0.9461
132 EDG 0.9461
133 G5V 0.9459
134 948 0.9458
135 FUC 0.9458
136 6M1 0.9456
137 RIP 0.9454
138 4SV 0.9447
139 82I 0.9446
140 DFU 0.9444
141 FUL 0.9443
142 ABN 0.9442
143 XM0 0.9440
144 GCS 0.9440
145 284 0.9440
146 JKE 0.9439
147 Q6T 0.9438
148 VNJ 0.9434
149 BDP 0.9433
150 B53 0.9433
151 94B 0.9432
152 G3F 0.9432
153 AKH 0.9432
154 ORO 0.9428
155 4PW 0.9427
156 HJP 0.9426
157 1WD 0.9422
158 DOB 0.9422
159 2LP 0.9421
160 C2U 0.9421
161 XYL 0.9419
162 RB5 0.9419
163 RB0 0.9419
164 KBG 0.9418
165 FA0 0.9418
166 URC 0.9417
167 SOE 0.9416
168 5WX 0.9413
169 SHG 0.9411
170 2DR 0.9410
171 24B 0.9408
172 5CU 0.9408
173 32O 0.9406
174 3WA 0.9405
175 APY 0.9403
176 1PT 0.9401
177 6HQ 0.9399
178 KJY 0.9394
179 JBK 0.9392
180 0MK 0.9391
181 5RG 0.9390
182 54G 0.9389
183 5NU 0.9386
184 NSP 0.9384
185 IP0 0.9380
186 ARA 0.9379
187 IDM 0.9379
188 TMZ 0.9378
189 95Z 0.9377
190 D1X 0.9377
191 QOS 0.9375
192 AMC 0.9373
193 CN0 0.9373
194 KYD 0.9372
195 BEW 0.9370
196 3FH 0.9370
197 TMT 0.9369
198 23W 0.9369
199 HIO 0.9365
200 ROR 0.9364
201 7WV 0.9364
202 ZZ3 0.9363
203 BHA 0.9363
204 PYJ 0.9361
205 HX3 0.9361
206 Z6J 0.9360
207 MCT 0.9358
208 GOO 0.9357
209 QDK 0.9356
210 7HQ 0.9355
211 A1U 0.9354
212 GTQ 0.9352
213 2AC 0.9350
214 2H5 0.9350
215 BEZ 0.9350
216 RP7 0.9348
217 V55 0.9348
218 4M0 0.9347
219 XQG 0.9345
220 5DI 0.9344
221 3V4 0.9344
222 L3Q 0.9342
223 8S0 0.9340
224 HMH 0.9340
225 1MR 0.9339
226 4CH 0.9338
227 FRU 0.9337
228 4ZE 0.9337
229 4HO 0.9337
230 KIB 0.9336
231 8TX 0.9336
232 6M4 0.9334
233 MSN 0.9333
234 ICC 0.9330
235 ECE 0.9330
236 MWM 0.9330
237 1MC 0.9329
238 B24 0.9329
239 285 0.9325
240 XBZ 0.9325
241 3OC 0.9325
242 BEN 0.9324
243 TDR 0.9323
244 H76 0.9323
245 BML 0.9322
246 INO 0.9322
247 KIA 0.9321
248 JFJ 0.9321
249 RCO 0.9321
250 S76 0.9320
251 FUF 0.9320
252 NBZ 0.9318
253 ZWZ 0.9317
254 2A7 0.9316
255 5M0 0.9316
256 NCA 0.9316
257 LDU 0.9315
258 ADK 0.9314
259 NBE 0.9314
260 PAF 0.9313
261 R1X 0.9312
262 YSO 0.9312
263 6LW 0.9310
264 BZ3 0.9308
265 BAM 0.9307
266 HPY 0.9306
267 ZB1 0.9305
268 NIO 0.9305
269 7VS 0.9305
270 3BZ 0.9305
271 0TR 0.9303
272 2CH 0.9303
273 MRY 0.9303
274 1P8 0.9303
275 TBP 0.9302
276 OXC 0.9301
277 DIU 0.9299
278 MZG 0.9295
279 DOR 0.9295
280 34A 0.9294
281 OAA 0.9294
282 HTS 0.9293
283 FAN 0.9293
284 4H2 0.9292
285 TM7 0.9291
286 4CL 0.9290
287 3ZQ 0.9289
288 HH5 0.9287
289 BVF 0.9286
290 PZA 0.9286
291 FBT 0.9286
292 TH7 0.9285
293 PY7 0.9284
294 XYD 0.9284
295 27Y 0.9284
296 BP9 0.9284
297 3CH 0.9283
298 PXL 0.9283
299 5QX 0.9283
300 SWA 0.9282
301 ICP 0.9281
302 PYD 0.9281
303 GIV 0.9281
304 2MP 0.9280
305 6MP 0.9279
306 42C 0.9279
307 IDH 0.9279
308 60P 0.9278
309 GAG 0.9278
310 4NC 0.9278
311 KPL 0.9276
312 7CZ 0.9275
313 NMJ 0.9275
314 M0Q 0.9275
315 B3R 0.9274
316 9CL 0.9274
317 271 0.9273
318 F0J 0.9272
319 P9P 0.9271
320 G4D 0.9270
321 LG3 0.9270
322 MYJ 0.9270
323 4JJ 0.9269
324 6PC 0.9266
325 TFU 0.9265
326 DHB 0.9264
327 2HO 0.9264
328 HT4 0.9262
329 SEJ 0.9262
330 UNU 0.9262
331 BR9 0.9261
332 PXM 0.9261
333 RM1 0.9260
334 2YU 0.9260
335 8EZ 0.9259
336 ADZ 0.9259
337 SHA 0.9259
338 5RN 0.9258
339 4HC 0.9258
340 CXF 0.9257
341 5UC 0.9257
342 UEG 0.9256
343 PHB 0.9256
344 9DA 0.9255
345 CYT 0.9255
346 SNE 0.9255
347 LKA 0.9254
348 JZ7 0.9254
349 DGJ 0.9254
350 9HX 0.9254
351 6X8 0.9254
352 CIG 0.9253
353 NPO 0.9252
354 4DX 0.9249
355 HZP 0.9248
356 MMA 0.9248
357 LG5 0.9247
358 DMV 0.9245
359 FPI 0.9245
360 IMR 0.9244
361 8GF 0.9243
362 JZ2 0.9242
363 HY1 0.9242
364 MFB 0.9241
365 GCB 0.9241
366 ICO 0.9240
367 9TW 0.9240
368 5MK 0.9239
369 6KX 0.9238
370 12M 0.9238
371 FCA 0.9238
372 93K 0.9237
373 BDR 0.9235
374 0P6 0.9235
375 GXL 0.9234
376 3MA 0.9233
377 3MG 0.9233
378 OHG 0.9233
379 PZI 0.9232
380 O7U 0.9228
381 3DO 0.9228
382 MWJ 0.9228
383 PEL 0.9227
384 9TZ 0.9227
385 KIV 0.9227
386 CHB 0.9227
387 SRT 0.9226
388 XXR 0.9225
389 PAB 0.9225
390 M3T 0.9224
391 VAH 0.9224
392 JIF 0.9223
393 DUC 0.9222
394 TZE 0.9219
395 GAF 0.9219
396 SVN 0.9219
397 HEW 0.9218
398 NDM 0.9218
399 51F 0.9215
400 EUG 0.9215
401 4CS 0.9215
402 PEA 0.9214
403 ABE 0.9211
404 43M 0.9211
405 GCU 0.9211
406 DBJ 0.9210
407 TEP 0.9210
408 PBC 0.9209
409 CRN 0.9208
410 SYG 0.9208
411 GLA 0.9207
412 TH0 0.9207
413 ES2 0.9207
414 DIG 0.9206
415 7WA 0.9206
416 ARW 0.9205
417 FCB 0.9205
418 2ZV 0.9203
419 4HM 0.9203
420 IPZ 0.9203
421 9MG 0.9202
422 938 0.9201
423 URQ 0.9200
424 IF7 0.9199
425 SS2 0.9197
426 5MH 0.9197
427 OVM 0.9197
428 9EW 0.9196
429 13X 0.9196
430 PM6 0.9195
431 XUL 0.9194
432 M1E 0.9194
433 THE 0.9191
434 HLZ 0.9191
435 DHK 0.9191
436 5JC 0.9190
437 RSF 0.9190
438 BR8 0.9189
439 LER 0.9189
440 8WO 0.9189
441 INE 0.9188
442 CAQ 0.9187
443 X6X 0.9186
444 ALL 0.9185
445 TLA 0.9184
446 XIY 0.9184
447 GDE 0.9183
448 ASN 0.9182
449 10L 0.9181
450 DHS 0.9180
451 PFB 0.9180
452 IHB 0.9180
453 VNL 0.9178
454 2FG 0.9177
455 GBD 0.9177
456 278 0.9174
457 RAM 0.9174
458 CIZ 0.9174
459 2CK 0.9174
460 EV0 0.9173
461 275 0.9173
462 1GN 0.9173
463 HLR 0.9172
464 JBE 0.9172
465 IPB 0.9172
466 ES4 0.9171
467 40O 0.9171
468 AZA 0.9171
469 1XM 0.9170
470 ES0 0.9170
471 7VJ 0.9170
472 3AB 0.9169
473 149 0.9168
474 717 0.9168
475 9X7 0.9167
476 D3M 0.9166
477 VK3 0.9166
478 H3M 0.9165
479 4XX 0.9164
480 CWM 0.9164
481 4XR 0.9164
482 RM4 0.9164
483 AS3 0.9162
484 QSC 0.9162
485 IGA 0.9162
486 5ZE 0.9159
487 LSA 0.9159
488 PYF 0.9158
489 24W 0.9157
490 SWD 0.9156
491 FUB 0.9155
492 N5J 0.9155
493 AX2 0.9154
494 2ZX 0.9154
495 4ZC 0.9154
496 5WY 0.9152
497 2AL 0.9152
498 JFD 0.9151
499 4MA 0.9151
500 HYA 0.9150
501 DQN 0.9150
502 BP1 0.9148
503 DEN 0.9148
504 282 0.9148
505 SX1 0.9147
506 AZG 0.9147
507 PBZ 0.9147
508 ALO 0.9144
509 67N 0.9144
510 RNS 0.9144
511 YTB 0.9143
512 3AY 0.9143
513 FB1 0.9142
514 MRZ 0.9141
515 FBA 0.9141
516 HHQ 0.9141
517 2EC 0.9140
518 YCP 0.9140
519 Z82 0.9140
520 RSO 0.9139
521 WDL 0.9138
522 AC0 0.9138
523 R8S 0.9138
524 EXO 0.9137
525 DTU 0.9136
526 141 0.9135
527 6AI 0.9135
528 4JL 0.9133
529 FPY 0.9133
530 MZW 0.9133
531 5AN 0.9133
532 UNC 0.9133
533 RBL 0.9131
534 SS1 0.9131
535 AC6 0.9131
536 293 0.9130
537 FBV 0.9130
538 CEE 0.9127
539 3MB 0.9127
540 GLT 0.9126
541 BNS 0.9126
542 0RW 0.9126
543 WOO 0.9123
544 4JO 0.9122
545 280 0.9122
546 GIO 0.9120
547 2A9 0.9119
548 1Y6 0.9119
549 25W 0.9118
550 AW5 0.9118
551 6CS 0.9117
552 G6D 0.9117
553 290 0.9117
554 YH7 0.9117
555 BOA 0.9115
556 GYE 0.9114
557 5AC 0.9114
558 WCE 0.9114
559 EVA 0.9113
560 A2F 0.9112
561 6AP 0.9112
562 XLS 0.9111
563 ERH 0.9111
564 9YL 0.9111
565 2K4 0.9110
566 3Z8 0.9110
567 2MH 0.9109
568 4JU 0.9109
569 MBG 0.9107
570 34D 0.9106
571 LRH 0.9105
572 HYP 0.9104
573 MAK 0.9104
574 F60 0.9103
575 6M9 0.9103
576 JZ9 0.9102
577 39A 0.9100
578 QSB 0.9100
579 OHP 0.9099
580 1DW 0.9098
581 1XN 0.9098
582 8GC 0.9098
583 TTY 0.9096
584 5H1 0.9095
585 BAE 0.9094
586 270 0.9092
587 ZXD 0.9091
588 EQT 0.9091
589 35C 0.9091
590 VAL 0.9091
591 J9W 0.9091
592 RHU 0.9090
593 4YS 0.9090
594 A65 0.9089
595 ISD 0.9089
596 YHO 0.9088
597 34V 0.9087
598 4M4 0.9086
599 5SG 0.9086
600 XQ0 0.9086
601 Y8I 0.9086
602 R9S 0.9085
603 TAR 0.9085
604 5IQ 0.9085
605 5MB 0.9085
606 15L 0.9085
607 ASC 0.9084
608 GOG 0.9084
609 2D0 0.9084
610 1NP 0.9083
611 14O 0.9083
612 LMR 0.9083
613 8WT 0.9083
614 AUD 0.9082
615 M58 0.9080
616 JPZ 0.9080
617 5Q0 0.9080
618 HQY 0.9080
619 ES1 0.9080
620 TLD 0.9078
621 ILE 0.9078
622 IPH 0.9078
623 AHB 0.9076
624 PRF 0.9074
625 MLT 0.9073
626 SVD 0.9073
627 4XV 0.9071
628 IUR 0.9070
629 IND 0.9070
630 93Q 0.9070
631 1SQ 0.9070
632 47J 0.9069
633 0R1 0.9069
634 CEJ 0.9068
635 MS9 0.9068
636 GVH 0.9067
637 5MI 0.9066
638 JBQ 0.9066
639 B2J 0.9065
640 HH8 0.9064
641 7NI 0.9063
642 2ZQ 0.9063
643 TAG 0.9062
644 LZ1 0.9061
645 YIO 0.9060
646 1LM 0.9059
647 5RO 0.9059
648 BZF 0.9058
649 680 0.9058
650 2CL 0.9057
651 II6 0.9056
652 OXQ 0.9056
653 INS 0.9056
654 40E 0.9055
655 M1H 0.9055
656 LDP 0.9054
657 8LG 0.9054
658 M2H 0.9054
659 ITN 0.9054
660 0CT 0.9052
661 4XH 0.9052
662 C2B 0.9051
663 6GU 0.9050
664 MPI 0.9050
665 HQD 0.9050
666 B0D 0.9049
667 G3P 0.9049
668 LZM 0.9049
669 PAV 0.9048
670 ES9 0.9047
671 2AS 0.9046
672 TNE 0.9046
673 CAM 0.9046
674 NTM 0.9044
675 HY3 0.9043
676 92Z 0.9041
677 1P3 0.9041
678 JTH 0.9041
679 1U6 0.9040
680 1AN 0.9040
681 BZI 0.9039
682 PDC 0.9039
683 5HN 0.9037
684 O72 0.9036
685 XX2 0.9036
686 CFP 0.9034
687 M1A 0.9031
688 FP2 0.9030
689 JBH 0.9029
690 KT7 0.9029
691 T9G 0.9028
692 DX4 0.9027
693 RUU 0.9027