Receptor
PDB id Resolution Class Description Source Keywords
2WA3 2.5 Å EC: 1.14.11.30 FACTOR INHIBITING HIF-1 ALPHA WITH 2-(3-HYDROXYPHENYL)-2-OXO ACID HOMO SAPIENS HYDROXYLASE DIOXYGENASE TRANSCRIPTION OXIDOREDUCTASE TRANSCRIPTION ACTIVATOR/INHIBITOR HYPOXIA
Ref.: STRUCTURAL BASIS FOR BINDING OF CYCLIC 2-OXOGLUTARA ANALOGUES TO FACTOR-INHIBITING HYPOXIA-INDUCIBLE FA BIOORG. MED. CHEM. LETT. V. 20 6125 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
A29 A:400;
Valid;
none;
ic50 = 1 mM
166.131 C8 H6 O4 c1cc(...
FE2 A:350;
Part of Protein;
none;
submit data
55.845 Fe [Fe+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2WA4 2.5 Å EC: 1.14.11.30 FACTOR INHIBITING HIF-1 ALPHA WITH N,3-DIHYDROXYBENZAMIDE HOMO SAPIENS HYDROXYLASE DIOXYGENASE TRANSCRIPTION OXIDOREDUCTASE TRANSCRIPTION ACTIVATOR/INHIBITOR HYPOXIA
Ref.: STRUCTURAL BASIS FOR BINDING OF CYCLIC 2-OXOGLUTARA ANALOGUES TO FACTOR-INHIBITING HYPOXIA-INDUCIBLE FA BIOORG. MED. CHEM. LETT. V. 20 6125 2010
Members (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5OPC ic50 = 29 uM A1Z C14 H11 Cl N2 O4 c1cc(cc(c1....
2 2W0X ic50 = 625 uM PD2 C7 H5 N O4 c1cnc(cc1C....
3 1MZF - AKG C5 H6 O5 C(CC(=O)O)....
4 2CGN - SIN C4 H6 O4 C(CC(=O)O)....
5 2WA4 ic50 = 18 uM 069 C7 H7 N O3 c1cc(cc(c1....
6 4Z2W - AKG C5 H6 O5 C(CC(=O)O)....
7 5OP8 ic50 = 66 uM A1H C13 H14 N8 O2 c1cn(nn1)C....
8 2WA3 ic50 = 1 mM A29 C8 H6 O4 c1cc(cc(c1....
9 4Z1V - OGA C4 H5 N O5 C(C(=O)O)N....
10 4AI8 ic50 > 100 uM DZA C6 H12 N2 O3 CN(C)NC(=O....
11 5OP6 ic50 = 21 uM A0W C19 H27 N3 O6 C1CCC(CC1)....
12 1MZE - TAR C4 H6 O6 [C@H]([C@@....
13 2YDE ic50 = 189 uM S2G C5 H8 O5 C(CC(=O)O)....
14 2YC0 ic50 = 1500 uM 2HG C5 H8 O5 C(CC(=O)O)....
70% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5OPC ic50 = 29 uM A1Z C14 H11 Cl N2 O4 c1cc(cc(c1....
2 2W0X ic50 = 625 uM PD2 C7 H5 N O4 c1cnc(cc1C....
3 1MZF - AKG C5 H6 O5 C(CC(=O)O)....
4 2CGN - SIN C4 H6 O4 C(CC(=O)O)....
5 2WA4 ic50 = 18 uM 069 C7 H7 N O3 c1cc(cc(c1....
6 4Z2W - AKG C5 H6 O5 C(CC(=O)O)....
7 5OP8 ic50 = 66 uM A1H C13 H14 N8 O2 c1cn(nn1)C....
8 2WA3 ic50 = 1 mM A29 C8 H6 O4 c1cc(cc(c1....
9 4Z1V - OGA C4 H5 N O5 C(C(=O)O)N....
10 4AI8 ic50 > 100 uM DZA C6 H12 N2 O3 CN(C)NC(=O....
11 5OP6 ic50 = 21 uM A0W C19 H27 N3 O6 C1CCC(CC1)....
12 1MZE - TAR C4 H6 O6 [C@H]([C@@....
13 2YDE ic50 = 189 uM S2G C5 H8 O5 C(CC(=O)O)....
14 2YC0 ic50 = 1500 uM 2HG C5 H8 O5 C(CC(=O)O)....
50% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5OPC ic50 = 29 uM A1Z C14 H11 Cl N2 O4 c1cc(cc(c1....
2 2W0X ic50 = 625 uM PD2 C7 H5 N O4 c1cnc(cc1C....
3 1MZF - AKG C5 H6 O5 C(CC(=O)O)....
4 2CGN - SIN C4 H6 O4 C(CC(=O)O)....
5 2WA4 ic50 = 18 uM 069 C7 H7 N O3 c1cc(cc(c1....
6 4Z2W - AKG C5 H6 O5 C(CC(=O)O)....
7 5OP8 ic50 = 66 uM A1H C13 H14 N8 O2 c1cn(nn1)C....
8 2WA3 ic50 = 1 mM A29 C8 H6 O4 c1cc(cc(c1....
9 4Z1V - OGA C4 H5 N O5 C(C(=O)O)N....
10 4AI8 ic50 > 100 uM DZA C6 H12 N2 O3 CN(C)NC(=O....
11 5OP6 ic50 = 21 uM A0W C19 H27 N3 O6 C1CCC(CC1)....
12 1MZE - TAR C4 H6 O6 [C@H]([C@@....
13 2YDE ic50 = 189 uM S2G C5 H8 O5 C(CC(=O)O)....
14 2YC0 ic50 = 1500 uM 2HG C5 H8 O5 C(CC(=O)O)....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: A29; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 A29 1 1
2 3HB 0.588235 0.842105
3 53C 0.527778 0.65
4 BQ4 0.488372 0.826087
5 173 0.444444 0.789474
Similar Ligands (3D)
Ligand no: 1; Ligand: A29; Similar ligands found: 1235
No: Ligand Similarity coefficient
1 SAF 0.9784
2 J9T 0.9766
3 069 0.9722
4 HQJ 0.9682
5 8OZ 0.9678
6 6TZ 0.9619
7 5QY 0.9613
8 L5V 0.9604
9 3PF 0.9601
10 GVG 0.9590
11 R20 0.9584
12 7MU 0.9581
13 PPY 0.9573
14 CH9 0.9569
15 D48 0.9563
16 MQN 0.9552
17 G3E 0.9549
18 JG8 0.9544
19 M3H 0.9539
20 KTA 0.9535
21 TT4 0.9535
22 KUF 0.9532
23 XDK 0.9531
24 4PN 0.9530
25 NCT 0.9521
26 J5I 0.9517
27 PIY 0.9516
28 BNL 0.9515
29 J9N 0.9513
30 COU 0.9512
31 3LR 0.9508
32 OCH 0.9508
33 2HQ 0.9502
34 H42 0.9501
35 DHY 0.9500
36 NIZ 0.9498
37 CFI 0.9497
38 IWT 0.9496
39 4JQ 0.9495
40 PIM 0.9492
41 5RO 0.9485
42 86J 0.9485
43 FBB 0.9482
44 JA8 0.9482
45 SE2 0.9475
46 0F9 0.9475
47 ASC 0.9473
48 MPV 0.9473
49 JF6 0.9473
50 45L 0.9470
51 R2P 0.9466
52 2AQ 0.9464
53 ES2 0.9459
54 HIS 0.9451
55 HHH 0.9451
56 ISZ 0.9448
57 K97 0.9447
58 1P8 0.9446
59 HJH 0.9443
60 0TU 0.9443
61 6RQ 0.9439
62 JB5 0.9437
63 269 0.9434
64 J6W 0.9434
65 LNR 0.9434
66 L22 0.9430
67 K2T 0.9429
68 9FL 0.9426
69 4FS 0.9426
70 4V2 0.9425
71 KJU 0.9424
72 9CA 0.9423
73 BGC 0.9423
74 3C4 0.9419
75 0BP 0.9418
76 03V 0.9415
77 1WC 0.9415
78 DIN 0.9414
79 9R5 0.9412
80 HHI 0.9409
81 DHI 0.9409
82 ES5 0.9407
83 VGD 0.9400
84 CWS 0.9399
85 BPY 0.9397
86 I1E 0.9396
87 BHO 0.9394
88 0N7 0.9393
89 15E 0.9392
90 1IT 0.9389
91 KT7 0.9389
92 GLC 0.9386
93 M1Z 0.9384
94 AOT 0.9382
95 2F6 0.9382
96 ET2 0.9381
97 HA5 0.9377
98 MSR 0.9377
99 3HP 0.9375
100 94W 0.9371
101 8WO 0.9371
102 VNL 0.9370
103 DNF 0.9370
104 ICO 0.9369
105 EDR 0.9367
106 SRO 0.9364
107 BEA 0.9363
108 LT2 0.9360
109 1A7 0.9359
110 46P 0.9357
111 ONR 0.9356
112 APG 0.9356
113 INO 0.9356
114 1L5 0.9354
115 S2P 0.9352
116 CLW 0.9352
117 463 0.9351
118 4YO 0.9350
119 5GU 0.9350
120 FDR 0.9347
121 36R 0.9347
122 A7W 0.9347
123 0P6 0.9347
124 XQ0 0.9346
125 4LW 0.9344
126 OGA 0.9344
127 N8Y 0.9343
128 BCU 0.9342
129 6ME 0.9342
130 QBK 0.9341
131 M4T 0.9340
132 3ID 0.9340
133 KKN 0.9340
134 AJV 0.9339
135 GZL 0.9338
136 FBM 0.9338
137 BZ2 0.9338
138 0HN 0.9337
139 DHB 0.9337
140 5RN 0.9337
141 OMD 0.9337
142 ZYR 0.9336
143 AZ9 0.9336
144 N2I 0.9335
145 AX3 0.9334
146 0JD 0.9334
147 PAC 0.9334
148 TIU 0.9333
149 6FZ 0.9332
150 TTL 0.9331
151 39O 0.9327
152 QUS 0.9326
153 15N 0.9322
154 XAZ 0.9322
155 B62 0.9321
156 KTJ 0.9320
157 4A3 0.9320
158 HQD 0.9319
159 4CS 0.9319
160 GAB 0.9319
161 NNO 0.9316
162 MYJ 0.9316
163 4NC 0.9315
164 MRW 0.9314
165 12T 0.9313
166 VXX 0.9313
167 0FO 0.9313
168 4MU 0.9313
169 6NT 0.9309
170 K34 0.9308
171 93K 0.9308
172 92K 0.9307
173 SHA 0.9307
174 5XC 0.9307
175 FHB 0.9307
176 FEH 0.9306
177 SMN 0.9306
178 J9Q 0.9305
179 52C 0.9305
180 12Q 0.9305
181 8CM 0.9302
182 URC 0.9302
183 PO6 0.9301
184 9FE 0.9301
185 MUA 0.9300
186 BZE 0.9299
187 DQU 0.9298
188 DMD 0.9298
189 9ZE 0.9297
190 RMN 0.9297
191 ALE 0.9295
192 ISN 0.9295
193 QY9 0.9295
194 E1T 0.9294
195 XHP 0.9294
196 PHU 0.9293
197 1P7 0.9293
198 D3G 0.9292
199 1KP 0.9292
200 F9P 0.9291
201 3QV 0.9290
202 TGX 0.9289
203 M2K 0.9289
204 AN3 0.9289
205 P9P 0.9289
206 I3A 0.9289
207 TOF 0.9288
208 E35 0.9287
209 5VM 0.9286
210 EN1 0.9286
211 3HM 0.9286
212 ICB 0.9284
213 OVV 0.9283
214 LDP 0.9282
215 Q03 0.9281
216 N2Z 0.9280
217 CK2 0.9279
218 9RW 0.9277
219 7VP 0.9277
220 263 0.9276
221 CHB 0.9276
222 HX4 0.9272
223 2FQ 0.9271
224 2HO 0.9271
225 8ZE 0.9269
226 PBA 0.9269
227 SNU 0.9269
228 ES7 0.9269
229 R9Y 0.9267
230 PJW 0.9267
231 97T 0.9267
232 JFJ 0.9266
233 MUC 0.9264
234 PZI 0.9263
235 ESP 0.9262
236 AJ2 0.9262
237 DE5 0.9261
238 HQT 0.9260
239 2AL 0.9259
240 L99 0.9256
241 MXN 0.9256
242 3BU 0.9252
243 1NP 0.9252
244 2BG 0.9251
245 1SQ 0.9251
246 ESX 0.9250
247 0HO 0.9250
248 DHQ 0.9250
249 N3W 0.9249
250 F4E 0.9249
251 Q02 0.9248
252 4P5 0.9248
253 GZ2 0.9247
254 0FK 0.9247
255 5OB 0.9247
256 3NT 0.9247
257 32X 0.9247
258 E7S 0.9246
259 XQI 0.9245
260 3AB 0.9245
261 CWJ 0.9244
262 8HC 0.9244
263 5WV 0.9244
264 BZ3 0.9243
265 8GC 0.9242
266 6KT 0.9239
267 PXL 0.9239
268 4WL 0.9238
269 2ZM 0.9237
270 NMJ 0.9237
271 KDG 0.9236
272 4JT 0.9235
273 344 0.9235
274 OTW 0.9235
275 7B3 0.9235
276 2UZ 0.9234
277 1F1 0.9232
278 JRB 0.9232
279 0W8 0.9231
280 FA0 0.9230
281 PH2 0.9229
282 MNN 0.9228
283 PEY 0.9227
284 5VL 0.9226
285 AKG 0.9225
286 1DJ 0.9222
287 K7M 0.9222
288 4Z4 0.9221
289 RJY 0.9218
290 8U3 0.9218
291 2HU 0.9218
292 4ME 0.9217
293 92P 0.9216
294 3OC 0.9216
295 EA1 0.9216
296 ZZ2 0.9215
297 GRO 0.9214
298 BZJ 0.9213
299 TPA 0.9213
300 SLS 0.9212
301 KJH 0.9212
302 AQO 0.9212
303 1LQ 0.9212
304 428 0.9211
305 7W1 0.9211
306 YZM 0.9210
307 F31 0.9210
308 6M9 0.9210
309 HNL 0.9209
310 CLZ 0.9209
311 6NI 0.9208
312 TZF 0.9208
313 KDV 0.9207
314 JAW 0.9206
315 5NI 0.9206
316 5HN 0.9206
317 AY4 0.9206
318 3NY 0.9205
319 5WZ 0.9205
320 SYV 0.9205
321 795 0.9204
322 CWM 0.9204
323 5QX 0.9202
324 PBZ 0.9201
325 SKM 0.9201
326 CPZ 0.9199
327 HDH 0.9197
328 R8V 0.9197
329 4ZA 0.9196
330 9TW 0.9196
331 ESI 0.9195
332 30G 0.9195
333 DE3 0.9195
334 44V 0.9194
335 AX7 0.9194
336 PE0 0.9194
337 M45 0.9193
338 3A9 0.9193
339 QX4 0.9193
340 44W 0.9192
341 IHB 0.9192
342 FHC 0.9192
343 X11 0.9191
344 2AK 0.9191
345 1Z6 0.9190
346 GJZ 0.9190
347 4BZ 0.9190
348 PHB 0.9190
349 8WT 0.9190
350 BDP 0.9190
351 SKA 0.9188
352 Q88 0.9187
353 T2D 0.9186
354 NDH 0.9185
355 75K 0.9185
356 IV2 0.9183
357 CTL 0.9182
358 4BY 0.9181
359 4BL 0.9181
360 AL0 0.9180
361 ORO 0.9180
362 B3U 0.9176
363 3Z8 0.9176
364 M5K 0.9176
365 JND 0.9176
366 CK1 0.9175
367 6HO 0.9175
368 1XA 0.9174
369 A5E 0.9173
370 XDE 0.9173
371 61M 0.9172
372 ABV 0.9171
373 GLU 0.9171
374 PDC 0.9171
375 V55 0.9171
376 2EC 0.9170
377 EOL 0.9170
378 3ZB 0.9169
379 5B1 0.9169
380 JDN 0.9167
381 E5X 0.9167
382 B60 0.9167
383 MVN 0.9166
384 WCE 0.9166
385 MAQ 0.9166
386 HBD 0.9165
387 ODO 0.9164
388 GDE 0.9164
389 24W 0.9164
390 ABI 0.9161
391 4HM 0.9161
392 8NX 0.9160
393 DOB 0.9160
394 3AL 0.9160
395 92G 0.9159
396 H4E 0.9158
397 XIY 0.9158
398 M1H 0.9155
399 FUD 0.9154
400 FA1 0.9153
401 0W1 0.9152
402 E7Z 0.9152
403 NPO 0.9152
404 TWO 0.9149
405 UNJ 0.9149
406 TYL 0.9149
407 MEW 0.9148
408 23J 0.9148
409 2HC 0.9147
410 RM1 0.9146
411 826 0.9144
412 RNT 0.9143
413 3DO 0.9143
414 5WY 0.9143
415 X0W 0.9142
416 4M0 0.9142
417 PAB 0.9142
418 JAE 0.9142
419 1LM 0.9141
420 2LY 0.9140
421 OTR 0.9140
422 AZ8 0.9140
423 5RG 0.9140
424 NVU 0.9140
425 HHR 0.9139
426 7Q1 0.9139
427 GTQ 0.9139
428 2K8 0.9138
429 X0U 0.9137
430 Z5P 0.9137
431 4AA 0.9137
432 BRT 0.9136
433 7VS 0.9135
434 M0Q 0.9135
435 4HC 0.9134
436 SQV 0.9133
437 X0V 0.9133
438 AOS 0.9132
439 MS9 0.9131
440 8TX 0.9130
441 PD2 0.9130
442 5JQ 0.9129
443 ES0 0.9129
444 D1X 0.9129
445 6CS 0.9129
446 H7Y 0.9128
447 8XL 0.9128
448 3BZ 0.9128
449 3MB 0.9128
450 HNK 0.9126
451 TTY 0.9126
452 M3E 0.9125
453 KW8 0.9125
454 BHA 0.9125
455 3QM 0.9124
456 ES1 0.9124
457 GLR 0.9119
458 GCO 0.9119
459 TH7 0.9119
460 1HN 0.9117
461 1M2 0.9117
462 4LV 0.9116
463 B55 0.9116
464 PHE 0.9115
465 PMF 0.9115
466 FK8 0.9113
467 PNZ 0.9113
468 DPN 0.9113
469 4HP 0.9113
470 XX2 0.9112
471 O72 0.9112
472 L14 0.9111
473 5CU 0.9111
474 Q24 0.9110
475 X48 0.9108
476 GAL 0.9108
477 MWP 0.9107
478 C2Y 0.9106
479 PQ0 0.9105
480 1Y6 0.9105
481 N5J 0.9105
482 2HG 0.9104
483 4MA 0.9104
484 4RU 0.9103
485 HCI 0.9103
486 268 0.9103
487 AJY 0.9103
488 TCA 0.9102
489 7W4 0.9102
490 2O6 0.9101
491 MR1 0.9100
492 54G 0.9100
493 5M0 0.9098
494 5IQ 0.9098
495 F12 0.9097
496 LPK 0.9096
497 C1M 0.9096
498 5TY 0.9096
499 492 0.9095
500 9UL 0.9095
501 GLO 0.9094
502 BTY 0.9094
503 GJP 0.9093
504 OXC 0.9093
505 GLN 0.9093
506 R9S 0.9091
507 0NX 0.9090
508 HHS 0.9090
509 ANN 0.9090
510 DBH 0.9090
511 HSO 0.9089
512 PRF 0.9089
513 3HA 0.9088
514 7QS 0.9088
515 RUY 0.9087
516 G12 0.9087
517 4VY 0.9084
518 6VD 0.9084
519 I4B 0.9084
520 FBW 0.9083
521 BPU 0.9082
522 4TU 0.9081
523 RAT 0.9081
524 36Y 0.9081
525 AC6 0.9079
526 2A9 0.9078
527 4XF 0.9078
528 B4O 0.9078
529 QSB 0.9077
530 Q71 0.9077
531 JPZ 0.9077
532 GO2 0.9076
533 FAN 0.9075
534 4FH 0.9075
535 XM0 0.9074
536 AMH 0.9073
537 SHI 0.9073
538 QWN 0.9073
539 QUZ 0.9073
540 YTX 0.9071
541 APZ 0.9071
542 TIH 0.9070
543 EV0 0.9069
544 M6N 0.9069
545 M4E 0.9068
546 BNF 0.9067
547 JLZ 0.9067
548 S2G 0.9066
549 HL4 0.9065
550 A7H 0.9063
551 Q6T 0.9062
552 1AL 0.9061
553 CXH 0.9060
554 P80 0.9060
555 8W9 0.9060
556 1QP 0.9059
557 4SX 0.9058
558 DHC 0.9057
559 HC4 0.9057
560 6QF 0.9056
561 5JL 0.9056
562 JYB 0.9056
563 OVM 0.9055
564 LFC 0.9054
565 7NI 0.9054
566 GF4 0.9050
567 4YS 0.9050
568 HFA 0.9049
569 AS3 0.9049
570 RA7 0.9049
571 HQ9 0.9049
572 DGN 0.9048
573 R9G 0.9047
574 YOF 0.9046
575 4NB 0.9046
576 SYC 0.9046
577 URS 0.9046
578 DAH 0.9045
579 B2J 0.9044
580 CFA 0.9044
581 9TZ 0.9042
582 PKU 0.9041
583 SOR 0.9041
584 GUA 0.9041
585 0RW 0.9041
586 HNH 0.9040
587 363 0.9039
588 EYV 0.9039
589 F60 0.9039
590 4M4 0.9038
591 AEG 0.9036
592 NPY 0.9035
593 F05 0.9035
594 YPN 0.9034
595 5NU 0.9033
596 SYM 0.9033
597 A09 0.9031
598 BP7 0.9030
599 F0J 0.9029
600 DGL 0.9028
601 DOR 0.9028
602 EUG 0.9028
603 HIC 0.9027
604 27B 0.9027
605 TAG 0.9025
606 DRL 0.9025
607 2D0 0.9025
608 TZM 0.9025
609 8IG 0.9025
610 9MG 0.9025
611 LSQ 0.9024
612 5SG 0.9024
613 14O 0.9023
614 5Q0 0.9023
615 68A 0.9022
616 P7Y 0.9020
617 HQY 0.9020
618 IAC 0.9019
619 9RH 0.9018
620 EGR 0.9017
621 CXF 0.9017
622 IOS 0.9017
623 DHK 0.9017
624 SVN 0.9017
625 42J 0.9016
626 6M4 0.9016
627 BZX 0.9014
628 M1E 0.9014
629 ZON 0.9013
630 270 0.9013
631 GOJ 0.9012
632 LYL 0.9012
633 AA 0.9012
634 5MK 0.9012
635 FGZ 0.9012
636 DEW 0.9010
637 ANC 0.9010
638 GXY 0.9010
639 OHP 0.9009
640 5H1 0.9008
641 33S 0.9006
642 P72 0.9006
643 0XT 0.9006
644 5MB 0.9006
645 P92 0.9003
646 QXW 0.9002
647 ZXD 0.9001
648 UNC 0.9001
649 KTW 0.9000
650 ARP 0.8999
651 7C3 0.8998
652 GGL 0.8998
653 I3E 0.8997
654 AVI 0.8997
655 7BC 0.8997
656 OW4 0.8997
657 6AI 0.8997
658 LQ2 0.8996
659 O2A 0.8995
660 3R4 0.8995
661 ROI 0.8995
662 MTL 0.8994
663 2KA 0.8994
664 5LA 0.8994
665 EKZ 0.8994
666 7ZE 0.8994
667 DIR 0.8993
668 JB8 0.8992
669 3M0 0.8992
670 NID 0.8992
671 7HQ 0.8991
672 6J9 0.8991
673 7B4 0.8991
674 NFA 0.8990
675 JF1 0.8989
676 2FY 0.8989
677 HF2 0.8988
678 MXD 0.8987
679 3IT 0.8987
680 BPN 0.8984
681 F2W 0.8984
682 FTV 0.8983
683 FK1 0.8983
684 SDD 0.8982
685 UN1 0.8981
686 EXD 0.8981
687 BQ2 0.8981
688 NYL 0.8980
689 HMH 0.8979
690 DEE 0.8978
691 SNO 0.8978
692 A3M 0.8978
693 HPS 0.8977
694 LZM 0.8977
695 B85 0.8976
696 0FR 0.8975
697 3F0 0.8975
698 F9Y 0.8974
699 UFO 0.8974
700 42A 0.8973
701 M6Z 0.8973
702 1DW 0.8973
703 GBN 0.8973
704 C9E 0.8972
705 DRG 0.8972
706 11S 0.8971
707 MLT 0.8971
708 NAG 0.8970
709 APS 0.8970
710 A13 0.8970
711 JXN 0.8969
712 2IT 0.8969
713 HHA 0.8969
714 Z82 0.8969
715 41K 0.8969
716 V1T 0.8968
717 ES9 0.8968
718 36E 0.8967
719 JBK 0.8965
720 1BN 0.8965
721 HBO 0.8963
722 TSR 0.8963
723 174 0.8963
724 OAA 0.8963
725 N0Z 0.8962
726 ANF 0.8962
727 FBJ 0.8962
728 B40 0.8961
729 FOT 0.8959
730 2D8 0.8958
731 PEA 0.8958
732 42C 0.8957
733 SD4 0.8956
734 KOJ 0.8956
735 9EW 0.8956
736 IYR 0.8955
737 ATX 0.8955
738 2MI 0.8955
739 TZL 0.8953
740 ZBT 0.8953
741 JBZ 0.8952
742 GNM 0.8950
743 264 0.8950
744 54D 0.8949
745 AW5 0.8949
746 QMP 0.8947
747 DHR 0.8947
748 QIC 0.8947
749 IFP 0.8946
750 M74 0.8945
751 XCZ 0.8943
752 M6H 0.8943
753 HL5 0.8942
754 1P3 0.8942
755 2CK 0.8942
756 I38 0.8941
757 EVF 0.8939
758 4NM 0.8938
759 7MX 0.8937
760 2FT 0.8936
761 BEZ 0.8936
762 J9W 0.8935
763 34D 0.8935
764 DI6 0.8935
765 226 0.8935
766 NCA 0.8934
767 SWA 0.8934
768 4A5 0.8934
769 PH3 0.8933
770 SN4 0.8932
771 717 0.8932
772 ZZZ 0.8931
773 FE DB1 0.8931
774 209 0.8931
775 MO8 0.8930
776 M6W 0.8929
777 28N 0.8929
778 3R6 0.8929
779 51R 0.8928
780 AC0 0.8928
781 BEN 0.8928
782 H4N 0.8928
783 FLV 0.8928
784 1VK 0.8927
785 DBX 0.8927
786 D2G 0.8926
787 FDB 0.8926
788 3YP 0.8926
789 LEL 0.8925
790 CXP 0.8925
791 XBT 0.8925
792 ADZ 0.8925
793 152 0.8924
794 2V0 0.8924
795 JR2 0.8924
796 5F5 0.8923
797 XRX 0.8923
798 PQK 0.8922
799 PBC 0.8922
800 JBH 0.8922
801 JZA 0.8921
802 ZME 0.8919
803 8NB 0.8919
804 6FB 0.8918
805 5XB 0.8917
806 L03 0.8917
807 4FA 0.8917
808 258 0.8916
809 AKH 0.8916
810 DX3 0.8914
811 5MI 0.8914
812 FBU 0.8914
813 EYK 0.8914
814 2LP 0.8914
815 XIZ 0.8911
816 GCU 0.8911
817 AEH 0.8909
818 7WR 0.8909
819 HY1 0.8908
820 GCS 0.8908
821 N7I 0.8908
822 RNO 0.8907
823 SQ4 0.8907
824 20J 0.8906
825 6PC 0.8906
826 UNU 0.8906
827 MAJ 0.8902
828 56D 0.8902
829 LDR 0.8902
830 S7S 0.8901
831 M5E 0.8901
832 CTS 0.8901
833 37T 0.8900
834 IJZ 0.8900
835 C2U 0.8900
836 OVP 0.8899
837 EWG 0.8899
838 UFV 0.8899
839 AMQ 0.8898
840 SRT 0.8898
841 BSX 0.8898
842 SQ7 0.8898
843 XRG 0.8897
844 GVY 0.8897
845 7O4 0.8897
846 URO 0.8897
847 RNS 0.8896
848 KJY 0.8896
849 DDU 0.8895
850 QBS 0.8895
851 6L6 0.8895
852 THA 0.8895
853 M1Q 0.8894
854 K80 0.8894
855 3VX 0.8893
856 9KT 0.8893
857 67N 0.8893
858 MES 0.8892
859 XYL 0.8891
860 S60 0.8891
861 RB5 0.8891
862 PBN 0.8891
863 2K4 0.8890
864 J0Z 0.8889
865 G3F 0.8889
866 AHN 0.8887
867 BK9 0.8886
868 SME 0.8885
869 0LH 0.8884
870 S8V 0.8883
871 N91 0.8882
872 TSS 0.8882
873 JU2 0.8882
874 0OC 0.8880
875 NIO 0.8879
876 M1A 0.8879
877 N2M 0.8878
878 AEF 0.8878
879 SXS 0.8878
880 YCP 0.8878
881 VM1 0.8877
882 BE2 0.8877
883 TYE 0.8876
884 E0O 0.8875
885 INE 0.8875
886 B5D 0.8873
887 259 0.8872
888 HSX 0.8870
889 HA7 0.8870
890 C53 0.8869
891 CCU 0.8868
892 CIT 0.8868
893 Q77 0.8868
894 HG3 0.8867
895 VOH 0.8867
896 DBJ 0.8867
897 SBK 0.8866
898 SR1 0.8866
899 SJ5 0.8866
900 SEP 0.8865
901 FF2 0.8864
902 XCG 0.8864
903 JZ7 0.8864
904 BAM 0.8864
905 SX1 0.8864
906 FCD 0.8863
907 60L 0.8863
908 Q7A 0.8863
909 EVA 0.8862
910 QPR 0.8861
911 MAH 0.8860
912 HJP 0.8860
913 XUL 0.8859
914 PRZ 0.8859
915 ENO 0.8859
916 HKD 0.8859
917 B2T 0.8857
918 SAN 0.8857
919 GUN 0.8856
920 NOJ 0.8855
921 3HG 0.8854
922 HLZ 0.8854
923 N9J 0.8853
924 PSJ 0.8852
925 8NY 0.8852
926 GYE 0.8851
927 C82 0.8850
928 GTR 0.8849
929 4J8 0.8849
930 PTU 0.8847
931 PCS 0.8846
932 EMZ 0.8845
933 LYS 0.8845
934 2ZQ 0.8845
935 SG2 0.8843
936 9AP 0.8843
937 8H8 0.8842
938 7MK 0.8841
939 549 0.8841
940 DYA 0.8840
941 AZA 0.8840
942 PRA 0.8839
943 PZA 0.8839
944 OOG 0.8838
945 AH8 0.8838
946 DNA 0.8838
947 4I8 0.8838
948 I6G 0.8838
949 HNT 0.8837
950 3FH 0.8836
951 PEL 0.8835
952 7ME 0.8834
953 BGU 0.8833
954 JP2 0.8833
955 8G0 0.8833
956 TSU 0.8833
957 NBZ 0.8832
958 CN0 0.8831
959 SS1 0.8831
960 X05 0.8830
961 78Y 0.8828
962 3PG 0.8827
963 TMG 0.8827
964 DTR 0.8827
965 0A9 0.8826
966 MEQ 0.8826
967 QIV 0.8826
968 TRP 0.8826
969 LMR 0.8826
970 36M 0.8825
971 GHM 0.8825
972 9BF 0.8824
973 KMH 0.8823
974 8S0 0.8821
975 7N0 0.8821
976 LI6 0.8820
977 RXA 0.8820
978 A5H 0.8817
979 VK3 0.8817
980 DPT 0.8816
981 E3X 0.8816
982 TIY 0.8816
983 DXG 0.8815
984 4KL 0.8815
985 GGB 0.8815
986 PYQ 0.8814
987 OK7 0.8812
988 TYR 0.8812
989 BHQ 0.8810
990 SOV 0.8810
991 5NE 0.8810
992 CS2 0.8809
993 GLY PRO 0.8808
994 DTY 0.8807
995 FBS 0.8807
996 6DP 0.8806
997 CFF 0.8806
998 091 0.8805
999 LL1 0.8805
1000 YRL 0.8804
1001 NQ 0.8804
1002 ZYQ 0.8803
1003 ABF 0.8801
1004 8GL 0.8801
1005 MD6 0.8800
1006 2QC 0.8799
1007 KMY 0.8797
1008 P84 0.8795
1009 5NS 0.8794
1010 K5W 0.8794
1011 BNS 0.8792
1012 W29 0.8791
1013 0FN 0.8791
1014 I59 0.8789
1015 ONL 0.8788
1016 3CR 0.8788
1017 3J8 0.8788
1018 0LO 0.8788
1019 KBB 0.8786
1020 55D 0.8785
1021 H33 0.8783
1022 GCB 0.8783
1023 MPK 0.8782
1024 LZ2 0.8782
1025 FCR 0.8782
1026 SSC 0.8781
1027 49O 0.8778
1028 NTN 0.8778
1029 0VT 0.8777
1030 293 0.8776
1031 XRS 0.8775
1032 MMS 0.8774
1033 OKG 0.8773
1034 JF2 0.8771
1035 OA3 0.8771
1036 ALL 0.8770
1037 AVA 0.8770
1038 BIK 0.8769
1039 B57 0.8769
1040 AAN 0.8769
1041 FF3 0.8768
1042 JXZ 0.8768
1043 LGC 0.8767
1044 KYA 0.8767
1045 M5H 0.8767
1046 SKF 0.8766
1047 4XV 0.8763
1048 AHR 0.8763
1049 505 0.8762
1050 BGP 0.8761
1051 H5B 0.8760
1052 G14 0.8760
1053 XAN 0.8760
1054 ROR 0.8758
1055 8MO 0.8757
1056 HX3 0.8756
1057 DLT 0.8755
1058 IQ5 0.8755
1059 ZEC 0.8754
1060 QDK 0.8753
1061 DAL DAL 0.8752
1062 GWM 0.8751
1063 5F8 0.8751
1064 AAS 0.8750
1065 XQG 0.8750
1066 RD4 0.8748
1067 3VW 0.8748
1068 B09 0.8748
1069 OW7 0.8747
1070 IOP 0.8747
1071 3AE 0.8745
1072 DA4 0.8744
1073 S0E 0.8744
1074 JXW 0.8743
1075 14J 0.8743
1076 MJ2 0.8742
1077 78U 0.8742
1078 QSC 0.8741
1079 GDL 0.8740
1080 ASO 0.8740
1081 2BX 0.8740
1082 SVD 0.8739
1083 FLC 0.8738
1084 4XS 0.8738
1085 261 0.8738
1086 SW7 0.8737
1087 RSO 0.8734
1088 3MF 0.8732
1089 JAH 0.8731
1090 PUE 0.8731
1091 WOE 0.8730
1092 3Y7 0.8727
1093 S2T 0.8727
1094 VGL 0.8727
1095 JKE 0.8727
1096 HPP 0.8726
1097 6X9 0.8725
1098 XLS 0.8725
1099 N4B 0.8724
1100 FP1 0.8723
1101 FYU 0.8723
1102 SOE 0.8722
1103 39U 0.8720
1104 3DM 0.8720
1105 RBL 0.8718
1106 FQX 0.8718
1107 QSH 0.8718
1108 ODK 0.8716
1109 LR5 0.8716
1110 NSP 0.8714
1111 RP5 0.8713
1112 FB2 0.8713
1113 ZZA 0.8712
1114 MP5 0.8712
1115 3VQ 0.8712
1116 BHH 0.8711
1117 IPB 0.8711
1118 9SE 0.8711
1119 C0H 0.8709
1120 F4K 0.8707
1121 TOH 0.8707
1122 M0W 0.8705
1123 NDG 0.8703
1124 HRM 0.8699
1125 GLY GLY 0.8695
1126 AMS 0.8694
1127 S7J 0.8692
1128 7WG 0.8692
1129 PMB 0.8690
1130 CCV 0.8689
1131 KYN 0.8689
1132 ISA 0.8688
1133 BRH 0.8688
1134 SYA 0.8687
1135 4BF 0.8687
1136 FBF 0.8687
1137 N8Z 0.8687
1138 2FX 0.8686
1139 M4S 0.8685
1140 WOO 0.8685
1141 ADA 0.8684
1142 6MW 0.8681
1143 PPT 0.8681
1144 KJM 0.8681
1145 HXY 0.8680
1146 M58 0.8679
1147 TJM 0.8674
1148 JGB 0.8674
1149 GV9 0.8673
1150 4HB 0.8672
1151 HMU 0.8672
1152 ZGL 0.8671
1153 DGJ 0.8671
1154 HLR 0.8670
1155 6OT 0.8668
1156 FQI 0.8666
1157 X09 0.8665
1158 1PS 0.8662
1159 IT2 0.8662
1160 WSD 0.8661
1161 XXG 0.8661
1162 JTH 0.8660
1163 D07 0.8659
1164 COI 0.8658
1165 4AV 0.8658
1166 54X 0.8657
1167 PZM 0.8655
1168 Y3L 0.8655
1169 4JC 0.8655
1170 2D2 0.8649
1171 OQC 0.8649
1172 AUV 0.8648
1173 JCZ 0.8648
1174 4NZ 0.8647
1175 K32 0.8646
1176 B56 0.8643
1177 X8Z 0.8642
1178 G2F 0.8641
1179 HNM 0.8640
1180 5GT 0.8639
1181 GNL 0.8638
1182 B1J 0.8638
1183 ZZT 0.8637
1184 TXW 0.8636
1185 FWD 0.8635
1186 4FF 0.8630
1187 MB1 0.8629
1188 LJ3 0.8629
1189 MOK 0.8629
1190 G4D 0.8627
1191 CIY 0.8627
1192 ORN 0.8625
1193 CKA 0.8625
1194 9LI 0.8621
1195 24B 0.8621
1196 2B4 0.8621
1197 S8D 0.8621
1198 NGO 0.8619
1199 LT1 0.8618
1200 XFE 0.8617
1201 5FL 0.8616
1202 R8S 0.8615
1203 BVA 0.8614
1204 AHC 0.8613
1205 S24 0.8612
1206 HPT 0.8611
1207 DUR 0.8608
1208 NF3 0.8607
1209 EOU 0.8598
1210 ARG 0.8598
1211 P81 0.8596
1212 PRL 0.8595
1213 NLA 0.8594
1214 9PL 0.8589
1215 STT 0.8588
1216 IF7 0.8587
1217 G3H 0.8583
1218 W81 0.8580
1219 CSN 0.8578
1220 SLC 0.8576
1221 EUE 0.8570
1222 XM5 0.8567
1223 TIA 0.8563
1224 GJS 0.8560
1225 GOE 0.8557
1226 ITE 0.8555
1227 5OO 0.8552
1228 IL5 0.8543
1229 U7E 0.8541
1230 G3P 0.8537
1231 537 0.8525
1232 E1K 0.8521
1233 LAO 0.8520
1234 DIE 0.8517
1235 3VS 0.8516
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2WA4; Ligand: 069; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2wa4.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2WA4; Ligand: 069; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2wa4.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2WA4; Ligand: 069; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2wa4.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 2WA4; Ligand: 069; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2wa4.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
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