Receptor
PDB id Resolution Class Description Source Keywords
3GMC 2.1 Å EC: 1.-.-.- CRYSTAL STRUCTURE OF 2-METHYL-3-HYDROXYPYRIDINE-5-CARBOXYLIC OXYGENASE WITH SUBSTRATE BOUND MESORHIZOBIUM LOTI FLAVIN MONOOXYGENASE OXIDOREDUCTASE
Ref.: STRUCTURE OF THE PLP DEGRADATIVE ENZYME 2-METHYL-3-HYDROXYPYRIDINE-5-CARBOXYLIC ACID OXYGEN MESORHIZOBIUM LOTI MAFF303099 AND ITS MECHANISTIC IMPLICATIONS. BIOCHEMISTRY V. 48 4139 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
3HM A:381;
B:381;
Valid;
Valid;
none;
none;
submit data
153.135 C7 H7 N O3 Cc1c(...
FAD A:380;
B:380;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5HXI 1.5 Å EC: 1.-.-.- 2-METHYL-3-HYDROXYPYRIDINE-5-CARBOXYLIC ACID OXYGENASE, 5HN RHIZOBIUM LOTI (STRAIN MAFF303099) ALPHA/BETA FOLD FLAVOENZYME SUBSTRATE COMPLEX OXIDOREDUCT
Ref.: ROLE OF THE TYR270 RESIDUE IN 2-METHYL-3-HYDROXYPYRIDINE-5-CARBOXYLIC ACID OXYGEN MESORHIZOBIUM LOTI J. BIOSCI. BIOENG. V. 123 154 2017
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 383 families.
1 5HXI Ki = 480 uM 5HN C6 H5 N O3 c1c(cncc1O....
2 3GMC - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 337 families.
1 5HXI Ki = 480 uM 5HN C6 H5 N O3 c1c(cncc1O....
2 3GMC - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 225 families.
1 5HXI Ki = 480 uM 5HN C6 H5 N O3 c1c(cncc1O....
2 3GMC - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 3HM; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 3HM 1 1
Ligand no: 2; Ligand: FAD; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 FAS 1 1
2 FAD 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 UBG 0.845588 0.987654
6 6FA 0.794118 0.987654
7 FAE 0.751773 0.987654
8 SFD 0.651007 0.860215
9 FDA 0.641892 0.906977
10 FNK 0.602564 0.876405
11 JNT 0.598425 0.876543
12 FAJ 0.57485 0.97561
13 62F 0.572327 0.939024
14 F2N 0.566265 0.886364
15 FMN 0.543307 0.876543
16 FA9 0.526316 0.939759
17 6YU 0.516304 0.860215
18 CNV FAD 0.511905 0.908046
19 P6G FDA 0.511628 0.908046
20 FAD NBT 0.508876 0.83871
21 A2D 0.504065 0.875
22 DAL FAD PER 0.491429 0.836957
23 P5F 0.491329 0.941176
24 FAD CNX 0.488506 0.8125
25 APR 0.488372 0.851852
26 AR6 0.488372 0.851852
27 FAD T2C 0.485876 0.819149
28 AGS 0.484615 0.811765
29 M33 0.484375 0.864198
30 BA3 0.484127 0.875
31 ATP 0.48062 0.851852
32 HEJ 0.48062 0.851852
33 B4P 0.480315 0.875
34 ADP 0.480315 0.851852
35 AP5 0.480315 0.875
36 ANP 0.477273 0.831325
37 5FA 0.476923 0.851852
38 AQP 0.476923 0.851852
39 48N 0.469388 0.902439
40 OAD 0.467626 0.876543
41 9X8 0.467626 0.833333
42 FAD NBA 0.467033 0.793814
43 GTA 0.465753 0.892857
44 AT4 0.465116 0.821429
45 AN2 0.465116 0.841463
46 HQG 0.463235 0.841463
47 AD9 0.462121 0.831325
48 3OD 0.460993 0.876543
49 RBF 0.460938 0.790123
50 FB0 0.460606 0.835165
51 139 0.460526 0.858824
52 AP0 0.46 0.835294
53 A22 0.459854 0.864198
54 ACP 0.458015 0.853659
55 8QN 0.456522 0.864198
56 PRX 0.454545 0.831325
57 A3R 0.453237 0.86747
58 A1R 0.453237 0.86747
59 G3A 0.452055 0.902439
60 T5A 0.45098 0.872093
61 G5P 0.44898 0.902439
62 ATF 0.448529 0.821429
63 50T 0.44697 0.819277
64 OZV 0.446043 0.851852
65 6YZ 0.445255 0.853659
66 ACQ 0.444444 0.853659
67 ADQ 0.442857 0.853659
68 PAJ 0.442857 0.847059
69 KMQ 0.441379 0.843373
70 8LE 0.441176 0.855422
71 5AL 0.441176 0.864198
72 ADX 0.439394 0.775281
73 CA0 0.439394 0.853659
74 8LQ 0.438849 0.865854
75 QA7 0.438849 0.855422
76 A4P 0.437909 0.831461
77 25L 0.4375 0.864198
78 P33 FDA 0.436464 0.817204
79 KG4 0.43609 0.853659
80 5SV 0.435714 0.793103
81 8LH 0.434783 0.843373
82 OMR 0.434211 0.818182
83 TXE 0.434211 0.890244
84 45A 0.434109 0.829268
85 ABM 0.434109 0.829268
86 AMP 0.433071 0.82716
87 A 0.433071 0.82716
88 4AD 0.432624 0.855422
89 ADJ 0.432258 0.818182
90 B5M 0.431507 0.878049
91 B5Y 0.431507 0.878049
92 BIS 0.430556 0.802326
93 DJC FAD 0.43 0.827957
94 SRA 0.429688 0.788235
95 AFH 0.42953 0.825581
96 DND 0.427632 0.865854
97 TXD 0.427632 0.890244
98 UP5 0.427632 0.878049
99 6V0 0.427632 0.857143
100 DQV 0.426667 0.8875
101 SRP 0.42446 0.843373
102 PR8 0.423611 0.837209
103 TAT 0.423358 0.821429
104 T99 0.423358 0.821429
105 AMO 0.422535 0.865854
106 PTJ 0.42069 0.835294
107 TXA 0.42069 0.865854
108 FYA 0.42069 0.864198
109 CNA 0.420382 0.865854
110 AHX 0.41958 0.835294
111 00A 0.41958 0.823529
112 AMP MG 0.418605 0.814815
113 MAP 0.41844 0.811765
114 NAI 0.418301 0.845238
115 AU1 0.41791 0.831325
116 A12 0.416667 0.843373
117 AP2 0.416667 0.843373
118 9ZD 0.415493 0.845238
119 25A 0.415493 0.851852
120 9ZA 0.415493 0.845238
121 COD 0.415094 0.842697
122 4TC 0.412903 0.879518
123 APC 0.411765 0.843373
124 ME8 0.410959 0.806818
125 1ZZ 0.410959 0.806818
126 NB8 0.410959 0.835294
127 ADP BEF 0.410448 0.82716
128 ADP MG 0.410448 0.82716
129 DJ0 FAD 0.41 0.865169
130 4UW 0.409091 0.825581
131 NAX 0.409091 0.837209
132 F2R 0.408805 0.850575
133 ADV 0.408759 0.843373
134 RBY 0.408759 0.843373
135 VO4 ADP 0.407143 0.809524
136 P1H 0.405882 0.818182
137 BEF ADP 0.405797 0.807229
138 OOB 0.405594 0.864198
139 LAD 0.40411 0.825581
140 UPA 0.403846 0.86747
141 4UU 0.401316 0.833333
142 GA7 0.401316 0.865854
143 A3D 0.401235 0.876543
144 80F 0.401235 0.808989
145 DLL 0.4 0.864198
146 XAH 0.4 0.806818
147 V2G 0.4 0.857143
Similar Ligands (3D)
Ligand no: 1; Ligand: 3HM; Similar ligands found: 1284
No: Ligand Similarity coefficient
1 4A3 1.0000
2 DHB 1.0000
3 2HO 1.0000
4 93K 1.0000
5 JLZ 1.0000
6 XX2 1.0000
7 FHB 1.0000
8 4NC 1.0000
9 MYJ 1.0000
10 CHB 1.0000
11 NNO 1.0000
12 P9P 1.0000
13 INO 1.0000
14 9TW 0.9993
15 QSB 0.9945
16 IHB 0.9900
17 PHB 0.9770
18 3HB 0.9765
19 HBD 0.9753
20 4CS 0.9750
21 8WO 0.9739
22 PAB 0.9737
23 F31 0.9730
24 GDE 0.9724
25 3NT 0.9712
26 NPO 0.9708
27 VNL 0.9706
28 GAB 0.9704
29 4MA 0.9704
30 WCE 0.9699
31 NMJ 0.9696
32 4AA 0.9689
33 SKM 0.9679
34 OVV 0.9676
35 1Y6 0.9674
36 3AB 0.9671
37 826 0.9667
38 5HN 0.9666
39 8GC 0.9664
40 174 0.9651
41 PBZ 0.9650
42 53C 0.9644
43 Z82 0.9643
44 4XR 0.9634
45 0HO 0.9633
46 BRT 0.9633
47 4ZA 0.9630
48 0HN 0.9628
49 ES7 0.9628
50 X0V 0.9626
51 AC6 0.9617
52 5WV 0.9613
53 SW7 0.9612
54 E7Z 0.9610
55 KKN 0.9610
56 GYE 0.9608
57 IFP 0.9604
58 4Z4 0.9600
59 3BZ 0.9599
60 DHK 0.9599
61 6NT 0.9592
62 KOJ 0.9588
63 3PF 0.9579
64 ISN 0.9578
65 4WL 0.9578
66 BGC 0.9578
67 5QY 0.9568
68 QSH 0.9566
69 4SX 0.9559
70 FGZ 0.9557
71 EKZ 0.9556
72 4P5 0.9550
73 3A9 0.9548
74 2ZM 0.9543
75 4FH 0.9540
76 J9Q 0.9540
77 2HU 0.9535
78 GZL 0.9535
79 3ID 0.9532
80 3NY 0.9532
81 ABI 0.9530
82 JAW 0.9525
83 1F1 0.9517
84 7W4 0.9514
85 G3E 0.9513
86 L99 0.9513
87 LDP 0.9513
88 86J 0.9512
89 DMD 0.9512
90 BEZ 0.9511
91 GLC 0.9510
92 FA0 0.9502
93 BZ2 0.9497
94 5NI 0.9494
95 J5I 0.9493
96 J9T 0.9490
97 TWO 0.9490
98 SE2 0.9486
99 HX3 0.9486
100 H42 0.9483
101 D48 0.9482
102 PZI 0.9481
103 VXX 0.9477
104 6NI 0.9476
105 NCA 0.9476
106 SYV 0.9475
107 R8V 0.9474
108 3HA 0.9465
109 LT2 0.9464
110 AHR 0.9464
111 PHU 0.9459
112 12Q 0.9458
113 2AL 0.9456
114 3F0 0.9455
115 2HQ 0.9454
116 HIS 0.9452
117 15N 0.9451
118 DOB 0.9450
119 DBH 0.9450
120 7W1 0.9447
121 BEN 0.9447
122 5OB 0.9446
123 AZ9 0.9446
124 5RO 0.9445
125 M2K 0.9445
126 BHA 0.9441
127 JDN 0.9440
128 M4T 0.9436
129 JB8 0.9433
130 ANN 0.9433
131 4M0 0.9430
132 GTQ 0.9429
133 HBA 0.9429
134 UNU 0.9428
135 D1X 0.9428
136 SKA 0.9427
137 6PC 0.9426
138 ORO 0.9425
139 CFI 0.9424
140 BAM 0.9422
141 PBC 0.9421
142 5RG 0.9421
143 PNZ 0.9421
144 5QX 0.9418
145 HQT 0.9417
146 TTL 0.9416
147 BDP 0.9415
148 5CU 0.9414
149 5XC 0.9412
150 2AQ 0.9409
151 HQJ 0.9407
152 67N 0.9406
153 V55 0.9404
154 4HM 0.9404
155 6RQ 0.9403
156 NIO 0.9403
157 BE2 0.9403
158 HQD 0.9402
159 ICO 0.9402
160 SAL 0.9402
161 E5X 0.9402
162 97T 0.9401
163 5RN 0.9400
164 Q88 0.9397
165 FE DB1 0.9393
166 BZ3 0.9393
167 M1A 0.9392
168 5M0 0.9392
169 HDH 0.9391
170 3M0 0.9391
171 F0J 0.9391
172 OAA 0.9391
173 COU 0.9390
174 JBK 0.9390
175 NBZ 0.9390
176 OCH 0.9389
177 OVM 0.9388
178 ICB 0.9388
179 4M4 0.9388
180 03V 0.9386
181 KUF 0.9385
182 YCP 0.9385
183 ES2 0.9384
184 FAN 0.9384
185 069 0.9384
186 4FS 0.9383
187 AC0 0.9383
188 6CS 0.9380
189 CWS 0.9378
190 ET2 0.9377
191 CLW 0.9374
192 1LQ 0.9374
193 NOJ 0.9374
194 DNF 0.9372
195 DIN 0.9370
196 EUG 0.9370
197 CWM 0.9368
198 AX7 0.9368
199 PZA 0.9368
200 3OC 0.9366
201 0JD 0.9365
202 A7W 0.9364
203 0P6 0.9364
204 54G 0.9364
205 0N7 0.9363
206 5NU 0.9361
207 RSO 0.9361
208 1SQ 0.9359
209 HA5 0.9357
210 FBS 0.9356
211 3MB 0.9355
212 ES0 0.9355
213 LNR 0.9355
214 FBW 0.9354
215 ES5 0.9353
216 TSU 0.9353
217 ABV 0.9352
218 ISZ 0.9352
219 XIY 0.9352
220 EA1 0.9351
221 GTR 0.9351
222 MS9 0.9349
223 TYL 0.9349
224 1P8 0.9349
225 OXC 0.9349
226 MQN 0.9348
227 9TZ 0.9348
228 1NP 0.9346
229 SOE 0.9344
230 VGD 0.9340
231 NTN 0.9340
232 36R 0.9337
233 FBB 0.9337
234 FOT 0.9337
235 4SV 0.9336
236 L5V 0.9335
237 270 0.9335
238 K2T 0.9334
239 XM0 0.9333
240 IV2 0.9332
241 DHR 0.9331
242 7WR 0.9330
243 UFV 0.9329
244 52C 0.9328
245 N5J 0.9327
246 1LM 0.9327
247 SS1 0.9327
248 4J8 0.9326
249 24W 0.9325
250 0W8 0.9325
251 JBH 0.9323
252 BEA 0.9323
253 4JQ 0.9322
254 ES6 0.9322
255 MLT 0.9322
256 0TU 0.9321
257 ESP 0.9321
258 3IT 0.9321
259 SAN 0.9320
260 5SG 0.9319
261 GLU 0.9319
262 8CM 0.9318
263 2K4 0.9316
264 1P7 0.9315
265 4XV 0.9314
266 E1T 0.9314
267 15L 0.9314
268 QWN 0.9314
269 5IQ 0.9312
270 2BG 0.9310
271 DYA 0.9309
272 AW5 0.9309
273 2MI 0.9308
274 ESX 0.9308
275 JPZ 0.9307
276 DOR 0.9307
277 TIU 0.9306
278 8WT 0.9304
279 34D 0.9303
280 ES1 0.9303
281 2FY 0.9303
282 O72 0.9303
283 JA8 0.9302
284 4YS 0.9301
285 FP1 0.9301
286 9CA 0.9300
287 9FL 0.9300
288 F60 0.9298
289 G3F 0.9298
290 7MU 0.9297
291 XQ0 0.9297
292 0F9 0.9297
293 92K 0.9293
294 5MK 0.9292
295 BHO 0.9291
296 BPN 0.9291
297 14O 0.9290
298 4VP 0.9290
299 DGJ 0.9289
300 5H1 0.9288
301 MRW 0.9288
302 BZX 0.9288
303 82I 0.9287
304 TPA 0.9287
305 PIM 0.9287
306 A29 0.9286
307 1IT 0.9286
308 5MI 0.9285
309 BE7 0.9284
310 173 0.9284
311 717 0.9284
312 6AI 0.9283
313 4FA 0.9283
314 VGL 0.9281
315 QXW 0.9280
316 4XS 0.9280
317 3XX 0.9279
318 4YO 0.9278
319 11S 0.9277
320 5Q0 0.9275
321 1M2 0.9274
322 NIZ 0.9274
323 QIC 0.9273
324 42J 0.9272
325 GVG 0.9272
326 92P 0.9271
327 ESI 0.9268
328 6M9 0.9267
329 ASO 0.9267
330 3U4 0.9266
331 4NM 0.9266
332 MSR 0.9266
333 PXL 0.9266
334 8S0 0.9264
335 Q6T 0.9261
336 SX1 0.9260
337 JAE 0.9259
338 9FE 0.9258
339 K97 0.9258
340 5VM 0.9256
341 JBE 0.9256
342 12T 0.9255
343 P92 0.9255
344 JB5 0.9255
345 I3A 0.9255
346 HMH 0.9255
347 QUZ 0.9255
348 HQY 0.9254
349 2A9 0.9254
350 UNC 0.9252
351 HHA 0.9250
352 15E 0.9250
353 6TZ 0.9250
354 MCT 0.9247
355 261 0.9247
356 51R 0.9246
357 CTL 0.9246
358 XCZ 0.9244
359 AEF 0.9244
360 FCR 0.9242
361 5MB 0.9242
362 5LA 0.9241
363 ZXD 0.9240
364 C2Y 0.9239
365 2D0 0.9238
366 JKE 0.9237
367 TH7 0.9234
368 SVD 0.9233
369 PIY 0.9232
370 AL0 0.9232
371 ODO 0.9232
372 GAL 0.9230
373 FK1 0.9230
374 45L 0.9230
375 OW4 0.9229
376 7HQ 0.9228
377 NPY 0.9227
378 OGA 0.9227
379 2HC 0.9226
380 H8N 0.9225
381 SHA 0.9221
382 URC 0.9221
383 1P3 0.9221
384 CN0 0.9219
385 PEA 0.9219
386 5B1 0.9217
387 DE5 0.9216
388 8ZE 0.9216
389 HJP 0.9215
390 F9P 0.9215
391 FYU 0.9214
392 ES9 0.9213
393 PAC 0.9213
394 ADA 0.9213
395 F05 0.9213
396 6FZ 0.9212
397 149 0.9212
398 2H5 0.9212
399 GCU 0.9211
400 H4N 0.9210
401 FA1 0.9210
402 JFJ 0.9210
403 1MC 0.9209
404 F9Y 0.9206
405 SLS 0.9206
406 MZG 0.9206
407 KJU 0.9206
408 QSC 0.9204
409 FQI 0.9203
410 7NI 0.9202
411 39O 0.9202
412 42C 0.9201
413 GCS 0.9201
414 259 0.9200
415 M58 0.9199
416 2LY 0.9198
417 4ME 0.9197
418 KTW 0.9196
419 IJZ 0.9195
420 M6N 0.9193
421 4JM 0.9191
422 1PT 0.9191
423 DHS 0.9190
424 XXG 0.9190
425 XYD 0.9189
426 CPZ 0.9189
427 C1M 0.9188
428 XBZ 0.9188
429 AAS 0.9187
430 AMS 0.9187
431 9ZE 0.9187
432 GUA 0.9187
433 4XH 0.9186
434 9EW 0.9186
435 CXF 0.9184
436 0RW 0.9182
437 ADE 0.9182
438 JZ2 0.9181
439 F4E 0.9181
440 GF4 0.9181
441 7B4 0.9180
442 23A 0.9179
443 RM1 0.9179
444 27Y 0.9178
445 4JJ 0.9177
446 K34 0.9177
447 3Z8 0.9177
448 QWW 0.9177
449 FBM 0.9176
450 2AC 0.9175
451 4HO 0.9174
452 HH8 0.9173
453 TZF 0.9173
454 G4D 0.9173
455 IT2 0.9173
456 4CL 0.9172
457 4JT 0.9172
458 GAF 0.9172
459 SNU 0.9171
460 SVN 0.9171
461 SN4 0.9169
462 MWJ 0.9168
463 2FG 0.9167
464 6M4 0.9166
465 SWD 0.9165
466 AKH 0.9164
467 XHP 0.9163
468 AJ2 0.9161
469 IPB 0.9160
470 TH0 0.9160
471 YRL 0.9160
472 4BZ 0.9160
473 ASC 0.9159
474 34A 0.9158
475 JG8 0.9158
476 LMR 0.9157
477 MR1 0.9157
478 GIV 0.9157
479 KT7 0.9156
480 GLA 0.9155
481 HLR 0.9154
482 275 0.9154
483 75K 0.9153
484 MWM 0.9153
485 AKG 0.9153
486 AMC 0.9153
487 N8Y 0.9152
488 URF 0.9152
489 TGX 0.9152
490 4ZE 0.9150
491 BR9 0.9148
492 I1E 0.9148
493 CH9 0.9148
494 IF7 0.9147
495 KBB 0.9147
496 B62 0.9147
497 8XL 0.9147
498 ADZ 0.9145
499 8NY 0.9144
500 AZ8 0.9144
501 HC4 0.9144
502 OK7 0.9143
503 2MP 0.9143
504 R20 0.9143
505 M0W 0.9143
506 OTR 0.9141
507 0W1 0.9139
508 RHU 0.9138
509 AJV 0.9136
510 ZYR 0.9135
511 5MH 0.9133
512 G6D 0.9133
513 5GU 0.9132
514 5JC 0.9131
515 EXD 0.9130
516 OVP 0.9130
517 A1U 0.9130
518 2CK 0.9129
519 K5W 0.9128
520 HT4 0.9128
521 M1H 0.9128
522 FA3 0.9128
523 HPA 0.9125
524 OTW 0.9124
525 2FQ 0.9124
526 XYP 0.9123
527 44W 0.9121
528 ONR 0.9121
529 TDR 0.9120
530 UNJ 0.9120
531 C2U 0.9119
532 1DW 0.9118
533 PYD 0.9117
534 ICP 0.9117
535 XAZ 0.9117
536 LZM 0.9115
537 8H8 0.9114
538 MBG 0.9114
539 2YU 0.9113
540 MEW 0.9113
541 Q24 0.9112
542 DQU 0.9112
543 7WV 0.9112
544 TTY 0.9112
545 MPV 0.9111
546 NDH 0.9110
547 LXC 0.9110
548 A13 0.9109
549 PYF 0.9108
550 43M 0.9105
551 MAJ 0.9105
552 TOF 0.9105
553 QBK 0.9105
554 0FO 0.9105
555 WBU 0.9103
556 C2B 0.9103
557 3FH 0.9102
558 FPI 0.9102
559 M0Q 0.9099
560 NSP 0.9099
561 EYK 0.9099
562 FBV 0.9098
563 42A 0.9096
564 PRZ 0.9095
565 0FK 0.9094
566 8HC 0.9094
567 PD2 0.9094
568 4HC 0.9094
569 7VS 0.9092
570 GUN 0.9092
571 DBX 0.9092
572 5UC 0.9091
573 F12 0.9091
574 J9W 0.9090
575 APZ 0.9089
576 36E 0.9089
577 6ME 0.9088
578 TM7 0.9087
579 4MU 0.9086
580 AJY 0.9086
581 14J 0.9086
582 FB2 0.9086
583 F81 0.9083
584 4JL 0.9083
585 2EC 0.9081
586 R8S 0.9080
587 PDC 0.9080
588 CWJ 0.9079
589 AQO 0.9079
590 BTY 0.9078
591 1WD 0.9078
592 AX3 0.9078
593 M5K 0.9077
594 10L 0.9077
595 P3K 0.9077
596 N2I 0.9076
597 M1E 0.9075
598 FDB 0.9074
599 3DM 0.9074
600 DHY 0.9074
601 9R5 0.9073
602 S76 0.9072
603 HBX 0.9071
604 MUA 0.9070
605 4RU 0.9069
606 4BY 0.9068
607 GRE 0.9068
608 DEN 0.9068
609 SRT 0.9067
610 X6X 0.9067
611 428 0.9067
612 GJP 0.9066
613 2CQ 0.9066
614 Y8I 0.9065
615 BSX 0.9062
616 RAT 0.9061
617 MWP 0.9061
618 G2F 0.9061
619 5JQ 0.9060
620 GXL 0.9060
621 PBA 0.9060
622 8TX 0.9059
623 ZZT 0.9058
624 94W 0.9057
625 FB1 0.9056
626 B57 0.9055
627 Z5P 0.9055
628 AZA 0.9055
629 ASP 0.9055
630 0FN 0.9054
631 1GN 0.9054
632 OMD 0.9054
633 6M1 0.9053
634 1KP 0.9052
635 4BL 0.9051
636 PE0 0.9051
637 CTS 0.9051
638 PEY 0.9050
639 PMB 0.9050
640 AY4 0.9050
641 6MP 0.9050
642 9DG 0.9050
643 HLZ 0.9049
644 M1Q 0.9049
645 GXY 0.9047
646 NK 0.9046
647 44V 0.9046
648 R9S 0.9046
649 VNJ 0.9045
650 XAN 0.9044
651 RIB 0.9043
652 TLD 0.9043
653 FDR 0.9041
654 9MG 0.9041
655 1HN 0.9039
656 KJY 0.9038
657 AMH 0.9037
658 8NX 0.9036
659 NCT 0.9036
660 1A7 0.9035
661 QX4 0.9035
662 B55 0.9035
663 GLN 0.9035
664 JTH 0.9035
665 9DA 0.9034
666 IND 0.9033
667 2HG 0.9033
668 JZ3 0.9032
669 SHG 0.9032
670 A5E 0.9031
671 XX3 0.9030
672 FBA 0.9030
673 ABN 0.9029
674 KJH 0.9028
675 4ZC 0.9028
676 150 0.9025
677 4JC 0.9025
678 XBT 0.9024
679 2O6 0.9023
680 PKU 0.9023
681 9HX 0.9023
682 JND 0.9023
683 3ZB 0.9022
684 H4E 0.9022
685 I3E 0.9022
686 FDK 0.9022
687 5WY 0.9022
688 KTA 0.9021
689 BPY 0.9021
690 EVA 0.9021
691 ORN 0.9021
692 KDV 0.9020
693 0R0 0.9020
694 HMU 0.9020
695 S2G 0.9019
696 4NB 0.9017
697 IFL 0.9017
698 FUD 0.9017
699 2AK 0.9016
700 M4S 0.9015
701 PEP 0.9015
702 IWT 0.9014
703 G5V 0.9012
704 37T 0.9012
705 LGC 0.9012
706 25W 0.9012
707 8G0 0.9011
708 LZ1 0.9011
709 4AV 0.9010
710 36Y 0.9010
711 MVN 0.9008
712 LQ2 0.9008
713 7HP 0.9007
714 1XN 0.9005
715 M4E 0.9005
716 2A7 0.9004
717 GV9 0.9004
718 IGA 0.9004
719 NAG 0.9004
720 IUR 0.9003
721 PY7 0.9003
722 8OZ 0.9003
723 BZI 0.9003
724 E7S 0.9003
725 TCA 0.9002
726 DIU 0.9001
727 7WA 0.9000
728 TSS 0.9000
729 PJW 0.8998
730 BZF 0.8998
731 QPR 0.8997
732 BP1 0.8997
733 2F6 0.8997
734 N2Z 0.8995
735 1SA 0.8995
736 INE 0.8994
737 JYB 0.8994
738 TEP 0.8992
739 SYN 0.8992
740 4JO 0.8991
741 OHP 0.8991
742 SNO 0.8989
743 6KT 0.8988
744 7WG 0.8987
745 FBU 0.8987
746 GAG 0.8987
747 NID 0.8985
748 A2F 0.8983
749 XDE 0.8982
750 VOH 0.8981
751 XQG 0.8980
752 4JP 0.8979
753 2LP 0.8977
754 AN3 0.8977
755 3DO 0.8977
756 6F0 0.8977
757 24B 0.8976
758 KYA 0.8975
759 DHQ 0.8973
760 GIF 0.8969
761 CFP 0.8969
762 32X 0.8969
763 3SK 0.8969
764 XXP 0.8969
765 8NB 0.8968
766 BTE 0.8964
767 DNC 0.8964
768 9KT 0.8963
769 EOL 0.8962
770 MT0 0.8962
771 RXA 0.8962
772 1WG 0.8961
773 F4Z 0.8960
774 IDM 0.8960
775 TT4 0.8959
776 P72 0.8955
777 LCN 0.8954
778 ES4 0.8954
779 SWA 0.8954
780 7ME 0.8953
781 J6W 0.8953
782 C21 0.8953
783 XRG 0.8950
784 1AL 0.8950
785 282 0.8950
786 KBZ 0.8950
787 MPI 0.8949
788 PHE 0.8949
789 JIF 0.8947
790 AZG 0.8947
791 M45 0.8946
792 CFF 0.8945
793 BCU 0.8944
794 VK3 0.8944
795 QY9 0.8944
796 T6C 0.8943
797 3HP 0.8942
798 NOY 0.8941
799 GVH 0.8941
800 MJ2 0.8941
801 141 0.8940
802 5JL 0.8940
803 TC7 0.8940
804 3R6 0.8940
805 COI 0.8939
806 ZBT 0.8939
807 EDR 0.8938
808 PM6 0.8938
809 290 0.8938
810 BNS 0.8936
811 6AP 0.8935
812 FH2 0.8935
813 3Z7 0.8935
814 YH7 0.8935
815 495 0.8934
816 DRL 0.8934
817 PYQ 0.8933
818 NQ 0.8932
819 0BP 0.8932
820 GCB 0.8931
821 0CT 0.8931
822 H7Y 0.8930
823 209 0.8930
824 OXQ 0.8930
825 GO2 0.8930
826 4TU 0.8929
827 0R1 0.8929
828 6R8 0.8928
829 MZB 0.8927
830 GBD 0.8925
831 LI6 0.8925
832 EGR 0.8924
833 45C 0.8923
834 BOA 0.8923
835 3QV 0.8921
836 PO6 0.8920
837 NBE 0.8918
838 7MH 0.8918
839 4V2 0.8917
840 268 0.8917
841 DX4 0.8917
842 J9N 0.8916
843 HPS 0.8915
844 IAC 0.8915
845 LYL 0.8913
846 PQK 0.8912
847 SOR 0.8912
848 3AL 0.8910
849 QMP 0.8910
850 6GU 0.8910
851 BCP 0.8910
852 DFB 0.8909
853 SYA 0.8905
854 EV0 0.8905
855 2DR 0.8904
856 8IG 0.8903
857 FPY 0.8903
858 AEH 0.8901
859 GJZ 0.8901
860 F5B 0.8901
861 3QM 0.8900
862 RB5 0.8899
863 1XM 0.8898
864 DEE 0.8898
865 9X7 0.8894
866 7MX 0.8894
867 6QF 0.8893
868 60P 0.8890
869 M1Z 0.8889
870 BNL 0.8889
871 PXM 0.8889
872 23J 0.8889
873 FUL 0.8888
874 YIO 0.8887
875 RNO 0.8887
876 EVF 0.8886
877 R8A 0.8886
878 2MH 0.8885
879 SMV 0.8884
880 PH2 0.8883
881 PRF 0.8882
882 AGK 0.8882
883 EN1 0.8882
884 N3W 0.8881
885 2ZV 0.8881
886 PHH 0.8880
887 CXH 0.8880
888 3SL 0.8880
889 HY1 0.8879
890 69O 0.8878
891 8W9 0.8877
892 7ZE 0.8876
893 BZJ 0.8875
894 DIE 0.8875
895 RMN 0.8875
896 MO8 0.8872
897 H62 0.8868
898 B53 0.8868
899 GWM 0.8867
900 C2A 0.8867
901 DA4 0.8866
902 7N0 0.8866
903 TZC 0.8866
904 2GS 0.8864
905 PRO 0.8863
906 GCO 0.8863
907 HZQ 0.8861
908 L3Q 0.8861
909 HH5 0.8861
910 XYS 0.8861
911 DBJ 0.8860
912 TLA 0.8860
913 ZZ3 0.8858
914 WOO 0.8857
915 IDH 0.8856
916 DFU 0.8856
917 PZM 0.8854
918 344 0.8853
919 ALL 0.8852
920 HY3 0.8852
921 7VP 0.8850
922 BP9 0.8850
923 RAM 0.8850
924 RSF 0.8850
925 27B 0.8849
926 SJ5 0.8848
927 HHR 0.8846
928 0MK 0.8846
929 OHG 0.8845
930 3WA 0.8844
931 JBN 0.8844
932 LKA 0.8844
933 MAN 0.8841
934 PA1 0.8841
935 LDU 0.8840
936 3C4 0.8839
937 KTJ 0.8839
938 APG 0.8839
939 X05 0.8837
940 PQ0 0.8837
941 AS3 0.8836
942 EMZ 0.8836
943 6OT 0.8834
944 H33 0.8834
945 DGL 0.8833
946 BNF 0.8833
947 PFB 0.8833
948 1DV 0.8832
949 JBQ 0.8831
950 6LW 0.8831
951 HSE 0.8831
952 PPY 0.8830
953 UAN 0.8829
954 RNS 0.8829
955 2ZQ 0.8828
956 RIP 0.8825
957 CLZ 0.8824
958 30G 0.8823
959 L22 0.8821
960 Q02 0.8821
961 13P 0.8821
962 OKG 0.8820
963 PEL 0.8818
964 2PG 0.8818
965 R9Y 0.8817
966 ALE 0.8815
967 SKF 0.8815
968 RUY 0.8815
969 TP5 0.8814
970 ASN 0.8813
971 K17 0.8813
972 KYD 0.8812
973 FK8 0.8811
974 FHC 0.8811
975 258 0.8809
976 FOA 0.8807
977 5VL 0.8807
978 BSP 0.8806
979 0CU 0.8806
980 FUC 0.8806
981 PRA 0.8806
982 URS 0.8806
983 ANF 0.8804
984 4P0 0.8804
985 463 0.8803
986 JZ5 0.8803
987 PCA 0.8802
988 BML 0.8801
989 1MR 0.8800
990 WOT 0.8800
991 B85 0.8798
992 A09 0.8798
993 SEP 0.8796
994 MET 0.8795
995 LEU 0.8795
996 JFD 0.8794
997 OXZ 0.8794
998 2PC 0.8794
999 FF2 0.8793
1000 URO 0.8793
1001 FBT 0.8793
1002 M5H 0.8793
1003 TBS 0.8792
1004 ROI 0.8792
1005 DMJ 0.8791
1006 PYC 0.8791
1007 HSM 0.8791
1008 F1A 0.8790
1009 SRO 0.8789
1010 TAG 0.8789
1011 DQA 0.8788
1012 GZ3 0.8788
1013 QBM 0.8787
1014 4CH 0.8787
1015 2K8 0.8787
1016 MNM 0.8786
1017 35C 0.8785
1018 YPN 0.8785
1019 L14 0.8784
1020 URQ 0.8783
1021 TBP 0.8783
1022 HHS 0.8783
1023 XIZ 0.8782
1024 95Z 0.8782
1025 AA 0.8781
1026 EQT 0.8781
1027 MZW 0.8781
1028 8XQ 0.8779
1029 HX4 0.8778
1030 UFO 0.8778
1031 B60 0.8777
1032 ANC 0.8775
1033 KGK 0.8773
1034 JXN 0.8773
1035 HSO 0.8772
1036 DS0 0.8772
1037 2QC 0.8771
1038 FUM 0.8769
1039 1X7 0.8767
1040 FRU 0.8767
1041 2FT 0.8765
1042 5XB 0.8765
1043 H76 0.8764
1044 61M 0.8764
1045 8K2 0.8761
1046 IFM 0.8761
1047 3PG 0.8761
1048 N7I 0.8761
1049 XYL 0.8760
1050 BK9 0.8760
1051 X09 0.8760
1052 LSA 0.8759
1053 JZ9 0.8758
1054 GIO 0.8758
1055 N91 0.8757
1056 NVU 0.8757
1057 FBF 0.8756
1058 39A 0.8756
1059 AZF 0.8756
1060 D07 0.8755
1061 PH3 0.8754
1062 265 0.8753
1063 4HP 0.8753
1064 KMT 0.8753
1065 AHB 0.8753
1066 1WC 0.8753
1067 IOS 0.8752
1068 CRS 0.8752
1069 9RW 0.8751
1070 1XA 0.8750
1071 X0W 0.8749
1072 1L5 0.8749
1073 6VD 0.8749
1074 MNN 0.8748
1075 MAQ 0.8748
1076 286 0.8746
1077 PEQ 0.8746
1078 1DU 0.8746
1079 4VY 0.8745
1080 2KA 0.8745
1081 12M 0.8745
1082 SXS 0.8744
1083 DX3 0.8743
1084 SIN 0.8743
1085 4NG 0.8742
1086 X0U 0.8742
1087 HDL 0.8741
1088 RCO 0.8741
1089 R2P 0.8740
1090 MXN 0.8739
1091 G12 0.8738
1092 1Z6 0.8738
1093 AH8 0.8736
1094 GHM 0.8735
1095 GNM 0.8735
1096 0XT 0.8732
1097 HHH 0.8731
1098 DGN 0.8731
1099 LRH 0.8730
1100 PCR 0.8730
1101 PXY 0.8728
1102 20J 0.8728
1103 K6X 0.8727
1104 4JU 0.8726
1105 KBG 0.8723
1106 4LW 0.8722
1107 B5D 0.8721
1108 GLT 0.8720
1109 S24 0.8719
1110 4HS 0.8718
1111 MAE 0.8716
1112 ARB 0.8716
1113 OW7 0.8714
1114 KMH 0.8711
1115 JU2 0.8710
1116 HEW 0.8709
1117 K32 0.8708
1118 4KL 0.8707
1119 M3H 0.8706
1120 GZ2 0.8706
1121 HGQ 0.8706
1122 449 0.8705
1123 S0E 0.8704
1124 BMA 0.8704
1125 ARP 0.8703
1126 28N 0.8703
1127 URA 0.8701
1128 NDM 0.8700
1129 A65 0.8700
1130 L7T 0.8700
1131 SR1 0.8700
1132 HQE 0.8700
1133 273 0.8700
1134 SME 0.8698
1135 SD4 0.8696
1136 CIG 0.8695
1137 091 0.8694
1138 UEG 0.8694
1139 Z6J 0.8691
1140 M2H 0.8691
1141 PLQ 0.8691
1142 GGL 0.8690
1143 SG2 0.8690
1144 FCA 0.8690
1145 AES 0.8690
1146 R2B 0.8689
1147 B3R 0.8689
1148 7B3 0.8687
1149 LG3 0.8686
1150 2D3 0.8686
1151 F4K 0.8685
1152 LG4 0.8685
1153 8U3 0.8685
1154 680 0.8685
1155 H5B 0.8683
1156 I6G 0.8683
1157 JAB 0.8682
1158 5NE 0.8682
1159 0TR 0.8682
1160 ADK 0.8682
1161 3CH 0.8681
1162 P7Y 0.8680
1163 1DJ 0.8680
1164 FCB 0.8680
1165 SMN 0.8679
1166 25R 0.8679
1167 XUL 0.8678
1168 M3T 0.8677
1169 HCI 0.8677
1170 TEO 0.8677
1171 HNQ 0.8675
1172 4A5 0.8675
1173 DA1 0.8675
1174 FPN 0.8675
1175 3R4 0.8674
1176 K22 0.8674
1177 5WX 0.8674
1178 TAR 0.8673
1179 RNT 0.8669
1180 7VJ 0.8669
1181 TSR 0.8667
1182 7CZ 0.8667
1183 CK2 0.8665
1184 BDF 0.8665
1185 SS2 0.8664
1186 HLD 0.8664
1187 O2A 0.8663
1188 IOL 0.8662
1189 KFH 0.8661
1190 PRY 0.8660
1191 QX2 0.8660
1192 2MN 0.8659
1193 JUG 0.8658
1194 1QP 0.8657
1195 4JN 0.8656
1196 5CL 0.8655
1197 E35 0.8655
1198 C9E 0.8654
1199 BPU 0.8652
1200 IP0 0.8652
1201 2BX 0.8651
1202 505 0.8650
1203 GJS 0.8650
1204 3HG 0.8645
1205 3J8 0.8643
1206 NYL 0.8643
1207 0GZ 0.8643
1208 MFB 0.8643
1209 F2W 0.8643
1210 7D2 0.8642
1211 YTX 0.8640
1212 X48 0.8639
1213 G1O 0.8639
1214 ABE 0.8637
1215 MRZ 0.8637
1216 W81 0.8637
1217 AMG 0.8636
1218 THA 0.8636
1219 329 0.8635
1220 LG5 0.8635
1221 CXP 0.8633
1222 NLE 0.8631
1223 NGO 0.8631
1224 GOJ 0.8631
1225 JZ4 0.8631
1226 DPT 0.8630
1227 4H2 0.8630
1228 K8X 0.8629
1229 KIB 0.8627
1230 P9E 0.8626
1231 BVF 0.8625
1232 TZE 0.8620
1233 FUF 0.8620
1234 5NS 0.8619
1235 0OC 0.8619
1236 J1Z 0.8618
1237 S2P 0.8617
1238 4NZ 0.8617
1239 LAO 0.8616
1240 LZ2 0.8615
1241 URP 0.8614
1242 ALA ALA 0.8611
1243 RD4 0.8609
1244 HKD 0.8609
1245 68A 0.8608
1246 HXX 0.8606
1247 26D 0.8605
1248 E3D 0.8605
1249 LDR 0.8604
1250 N0Z 0.8602
1251 3BU 0.8600
1252 9AP 0.8598
1253 2AS 0.8595
1254 4I8 0.8594
1255 293 0.8590
1256 HQ9 0.8590
1257 DNA 0.8588
1258 XQK 0.8588
1259 9PY 0.8585
1260 V1T 0.8577
1261 5TY 0.8576
1262 GLO 0.8574
1263 ICF 0.8571
1264 HHQ 0.8570
1265 M6W 0.8567
1266 DHC 0.8565
1267 6BL 0.8564
1268 0LH 0.8563
1269 BNT 0.8562
1270 X8D 0.8561
1271 PYJ 0.8558
1272 3MG 0.8555
1273 GBN 0.8555
1274 MAK 0.8554
1275 DPZ 0.8550
1276 APY 0.8550
1277 S7J 0.8544
1278 EUE 0.8536
1279 G3H 0.8535
1280 JP2 0.8528
1281 FA6 0.8520
1282 ZWZ 0.8520
1283 AEG 0.8505
1284 GLY GLY 0.8502
Ligand no: 2; Ligand: FAD; Similar ligands found: 1
No: Ligand Similarity coefficient
1 FDA T2C 0.8610
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5HXI; Ligand: FAD; Similar sites found with APoc: 3
This union binding pocket(no: 1) in the query (biounit: 5hxi.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 4BJZ P3A 38.5224
2 4BJZ FAD 38.5224
3 4J36 1HR 39.314
Pocket No.: 2; Query (leader) PDB : 5HXI; Ligand: FAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5hxi.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 5HXI; Ligand: FAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 5hxi.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 5HXI; Ligand: FAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5hxi.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 5HXI; Ligand: 5HN; Similar sites found with APoc: 2
This union binding pocket(no: 5) in the query (biounit: 5hxi.bio1) has 41 residues
No: Leader PDB Ligand Sequence Similarity
1 4BJZ P3A 38.5224
2 4BJZ FAD 38.5224
Pocket No.: 6; Query (leader) PDB : 5HXI; Ligand: 5HN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 5hxi.bio1) has 41 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 5HXI; Ligand: 5HN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 5hxi.bio1) has 41 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 5HXI; Ligand: 5HN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 5hxi.bio1) has 41 residues
No: Leader PDB Ligand Sequence Similarity
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