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Receptor

PDB id	Resolution	Class	Description	Source	Keywords
3VDQ	2.2 Å	EC: 1.1.1.30	CRYSTAL STRUCTURE OF ALCALIGENES FAECALIS D-3-HYDROXYBUTYRAT DEHYDROGENASE IN COMPLEX WITH NAD(+) AND ACETATE	ALCALIGENES FAECALIS	NAD DEPENDENT ENZYME HYDROXYBUTYRATE DEHYDROGENASE KETONE OXIDOREDUCTASE
Ref.:	THE STRUCTURES OF ALCALIGENES FAECALIS D-3-HYDROXYB DEHYDROGENASE BEFORE AND AFTER NAD+ AND ACETATE BIN SUGGEST A DYNAMICAL REACTION MECHANISM AS A MEMBER SDR FAMILY. ACTA CRYSTALLOGR.,SECT.D V. 64 496 2008

Ligand

Ligand	Chain:Residue	Validity	Ligand Warnings	Binding Data	Molecular Weight (Da)	Formula	SMILES
ACT	A:301; B:301; C:302; D:301;	Invalid; Invalid; Invalid; Invalid;	none; none; none; none;	submit data	59.044	C2 H3 O2	CC(=O...
CA	B:304; C:301;	Part of Protein; Part of Protein;	none; none;	submit data	40.078	Ca	[Ca+2...
CL	A:302; B:302; C:303; D:302;	Invalid; Invalid; Invalid; Invalid;	none; none; none; none;	submit data	35.453	Cl	[Cl-]
NAD	A:303; B:303; C:304; D:303;	Valid; Valid; Valid; Valid;	none; none; none; none;	submit data	663.425	C21 H27 N7 O14 P2	c1cc(...

View in 3D viewer

90% Homology Family

Leader

PDB id	Resolution	Class	Description	Source	Keywords
5B4T	1.19 Å	EC: 1.1.1.30	CRYSTAL STRUCTURE OF D-3-HYDROXYBUTYRATE DEHYDROGENASE FROM ALCALIGENES FAECALIS COMPLEXED WITH NAD+ AND A SUBSTRATE D-H YDROXYBUTYRATE	ALCALIGENES FAECALIS	SHORT-CHAIN DEHYDROGENASES/REDUCTASES SUBSTRATE COMPLEX OXIDOREDUCTASE
Ref.:	STRUCTURAL INSIGHTS INTO THE CATALYTIC REACTION TRI INHIBITION OF D-3-HYDROXYBUTYRATE DEHYDROGENASE ACTA CRYSTALLOGR.,SECT.F V. 72 507 2016

Members (4)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 3 families.
1	5B4T	-	3HR	C4 H8 O3	C[C@H](CC(....
2	3VDQ	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
3	5B4V	-	DXX	C4 H6 O4	CC(C(=O)O)....
4	5B4U	-	MLA	C3 H4 O4	C(C(=O)O)C....

70% Homology Family (12)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 1 families.
1	5YSS	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
2	2ZTL	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
3	2ZTU	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
4	2ZTM	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
5	1X1T	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
6	2ZTV	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
7	2Q2V	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
8	2Q2Q	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
9	5B4T	-	3HR	C4 H8 O3	C[C@H](CC(....
10	3VDQ	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
11	5B4V	-	DXX	C4 H6 O4	CC(C(=O)O)....
12	5B4U	-	MLA	C3 H4 O4	C(C(=O)O)C....

50% Homology Family (5)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 4 families.
1	1X7H	-	NDP	C21 H30 N7 O17 P3	c1nc(c2c(n....
2	1W4Z	-	NAP	C21 H28 N7 O17 P3	c1cc(c[n+]....
3	2Q2V	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
4	3VDQ	-	NAD	C21 H27 N7 O14 P2	c1cc(c[n+]....
5	2DTE	-	NAI	C21 H29 N7 O14 P2	c1nc(c2c(n....

Polypharmacology

Similar Ligands (2D)

Ligand no: 1; Ligand: NAD; Similar ligands found: 251

No:	Ligand	ECFP6 Tc	MDL keys Tc
1	NAD IBO	0.885714	0.985915
2	NAD TDB	0.885714	0.985915
3	A3D	0.872727	0.986111
4	NHD	0.821429	0.972222
5	NAP	0.811966	0.986111
6	NFD	0.791304	0.946667
7	DND	0.765766	0.972603
8	AMP NAD	0.74359	0.972222
9	ZID	0.737705	0.986111
10	NAQ	0.729508	0.934211
11	NAE	0.721311	0.959459
12	NA0	0.712	0.972603
13	TAP	0.704	0.921053
14	NDE	0.689922	0.972603
15	NAJ	0.683333	0.972222
16	NDC	0.679389	0.934211
17	NDO	0.674603	0.958904
18	N01	0.656	0.972222
19	CNA	0.642276	0.972603
20	NBP	0.621212	0.922078
21	NAD BBN	0.609929	0.876543
22	8ID	0.609756	0.922078
23	NAD CJ3	0.601399	0.845238
24	ADP MG	0.584906	0.957747
25	ADP BEF	0.584906	0.957747
26	A2D	0.576923	0.958333
27	ADP	0.575472	0.931507
28	NGD	0.574803	0.922078
29	BA3	0.566038	0.958333
30	NAD NDT	0.565789	0.755319
31	M33	0.564815	0.918919
32	ADP PO3	0.563636	0.957747
33	ATP MG	0.563636	0.957747
34	AP5	0.560748	0.958333
35	B4P	0.560748	0.958333
36	BEF ADP	0.558559	0.931507
37	VO4 ADP	0.557522	0.932432
38	AT4	0.555556	0.894737
39	AN2	0.555556	0.918919
40	GAP	0.553571	0.932432
41	OOB	0.551724	0.972222
42	CA0	0.550459	0.932432
43	9JJ	0.546053	0.898734
44	ATP	0.545455	0.931507
45	HEJ	0.545455	0.931507
46	ACP	0.545455	0.906667
47	KG4	0.545455	0.932432
48	DQV	0.544	0.972222
49	ALF ADP	0.54386	0.883117
50	ANP MG	0.54386	0.945205
51	DAL AMP	0.543103	0.945205
52	8LQ	0.543103	0.92
53	AQP	0.540541	0.931507
54	APR	0.540541	0.931507
55	AR6	0.540541	0.931507
56	5FA	0.540541	0.931507
57	AGS	0.535714	0.883117
58	AD9	0.535714	0.906667
59	WAQ	0.533333	0.896104
60	ABM	0.53271	0.905405
61	45A	0.53271	0.905405
62	QA7	0.529915	0.907895
63	DLL	0.529412	0.972222
64	00A	0.529412	0.921053
65	AMP MG	0.528302	0.943662
66	ANP	0.526316	0.906667
67	NJP	0.526316	0.959459
68	ACQ	0.526316	0.906667
69	OAD	0.525	0.932432
70	ADX	0.522523	0.839506
71	8LE	0.521739	0.907895
72	5AL	0.521739	0.945205
73	A1R	0.521008	0.871795
74	9SN	0.520325	0.909091
75	A	0.518868	0.930556
76	AMP	0.518868	0.930556
77	50T	0.517857	0.893333
78	ATF	0.517241	0.894737
79	3OD	0.516393	0.932432
80	1ZZ	0.516393	0.851852
81	SON	0.513514	0.92
82	PRX	0.513274	0.881579
83	SRP	0.512821	0.92
84	8LH	0.512821	0.92
85	6YZ	0.512821	0.906667
86	3UK	0.512397	0.958904
87	9X8	0.512397	0.883117
88	ADP BMA	0.512397	0.932432
89	MYR AMP	0.512195	0.851852
90	NAJ PZO	0.510949	0.909091
91	NMN	0.509434	0.875
92	HQG	0.508475	0.918919
93	A3R	0.508333	0.871795
94	B5V	0.508197	0.945946
95	AMP DBH	0.507937	0.906667
96	A22	0.504202	0.945205
97	JNT	0.504132	0.906667
98	FA5	0.504	0.945946
99	ATP A	0.504	0.971831
100	ATP A A A	0.504	0.971831
101	B5M	0.504	0.933333
102	8QN	0.5	0.945205
103	NAX	0.496183	0.886076
104	PR8	0.495935	0.8625
105	ADQ	0.495868	0.932432
106	AMO	0.495868	0.92
107	4AD	0.495868	0.933333
108	PAJ	0.495868	0.873418
109	V2G	0.495726	0.884615
110	APC MG	0.495652	0.931507
111	A12	0.495495	0.894737
112	AP2	0.495495	0.894737
113	ALF ADP 3PG	0.492424	0.873418
114	AHZ	0.492308	0.851852
115	FYA	0.491935	0.918919
116	AHX	0.491803	0.884615
117	4UU	0.488372	0.933333
118	5SV	0.487603	0.8375
119	T99	0.487179	0.894737
120	TAT	0.487179	0.894737
121	APC	0.486957	0.894737
122	SRA	0.486239	0.881579
123	6V0	0.484848	0.909091
124	NAI	0.484848	0.921053
125	GTA	0.484615	0.898734
126	LAD	0.483871	0.873418
127	AU1	0.482456	0.906667
128	F2R	0.481752	0.831325
129	TXE	0.481203	0.921053
130	OMR	0.481203	0.841463
131	AF3 ADP 3PG	0.481203	0.873418
132	LAQ	0.480916	0.851852
133	G3A	0.48062	0.909091
134	B5Y	0.480315	0.933333
135	NB8	0.48	0.884615
136	TXA	0.48	0.92
137	BIS	0.48	0.871795
138	PTJ	0.48	0.884615
139	ME8	0.48	0.851852
140	139	0.477941	0.886076
141	LPA AMP	0.477273	0.851852
142	G5P	0.476923	0.909091
143	AFH	0.476923	0.873418
144	AR6 AR6	0.476923	0.958333
145	ARG AMP	0.476923	0.841463
146	25L	0.47619	0.945205
147	NAJ PYZ	0.475524	0.864198
148	9ZA	0.47541	0.896104
149	9ZD	0.47541	0.896104
150	OZV	0.47541	0.931507
151	25A	0.47541	0.958333
152	DZD	0.47482	0.897436
153	TXD	0.473684	0.921053
154	4UV	0.472868	0.933333
155	TYM	0.470149	0.945946
156	ADV	0.470085	0.894737
157	RBY	0.470085	0.894737
158	A7R	0.469231	0.857143
159	KMQ	0.46875	0.894737
160	4TA	0.467626	0.864198
161	48N	0.466165	0.884615
162	XAH	0.465116	0.851852
163	4UW	0.462687	0.897436
164	M24	0.461538	0.886076
165	80F	0.460993	0.853659
166	IOT	0.459854	0.821429
167	T5A	0.456522	0.853659
168	L3W	0.455882	0.92
169	EAD	0.455782	0.886076
170	MAP	0.455285	0.883117
171	GA7	0.454545	0.894737
172	BT5	0.453901	0.821429
173	A4P	0.452555	0.833333
174	UP5	0.451852	0.933333
175	PAP	0.445378	0.917808
176	AP0	0.445255	0.884615
177	4TC	0.445255	0.909091
178	YLP	0.444444	0.831325
179	P1H	0.443709	0.864198
180	AOC	0.442478	0.810811
181	Z5A	0.439189	0.833333
182	LMS	0.4375	0.817073
183	2A5	0.436975	0.857143
184	COD	0.43662	0.802326
185	ADJ	0.435714	0.841463
186	YLC	0.434783	0.851852
187	YLB	0.434783	0.831325
188	ATR	0.433333	0.90411
189	7MD	0.432836	0.851852
190	8X1	0.432	0.764045
191	G5A	0.429752	0.790698
192	PO4 PO4 A A A A PO4	0.429688	0.943662
193	TAD	0.42963	0.873418
194	D4F	0.428571	0.875
195	5AS	0.42735	0.770115
196	BTX	0.426573	0.831325
197	YLA	0.425532	0.831325
198	DSZ	0.425197	0.790698
199	NCN	0.424779	0.805556
200	UPA	0.42446	0.921053
201	8PZ	0.424242	0.811765
202	VMS	0.424	0.8
203	54H	0.424	0.8
204	9K8	0.423077	0.744444
205	N0B	0.422819	0.853659
206	6AD	0.422764	0.85
207	AYB	0.422535	0.821429
208	7D3	0.422414	0.844156
209	YLY	0.421769	0.821429
210	TSB	0.420635	0.809524
211	ODP	0.41958	0.922078
212	A5A	0.419355	0.819277
213	FB0	0.419355	0.775281
214	AV2	0.419355	0.855263
215	NNR	0.419048	0.739726
216	LEU LMS	0.418605	0.761364
217	649	0.417266	0.775281
218	H1Q	0.416667	0.917808
219	NMN AMP PO4	0.416667	0.933333
220	SSA	0.416	0.790698
221	P5A	0.415385	0.755556
222	LSS	0.414062	0.772727
223	52H	0.412698	0.790698
224	A2R	0.412698	0.918919
225	JB6	0.412214	0.896104
226	5N5	0.411215	0.783784
227	YSA	0.410448	0.811765
228	B1U	0.410448	0.786517
229	53H	0.409449	0.790698
230	5CA	0.409449	0.790698
231	ITT	0.408333	0.878378
232	7D4	0.408333	0.844156
233	NA7	0.407692	0.894737
234	5CD	0.407407	0.794521
235	0WD	0.406897	0.909091
236	A3P	0.40678	0.930556
237	HFD	0.406504	0.883117
238	JSQ	0.406504	0.883117
239	AVV	0.40625	0.860759
240	RAB	0.40566	0.808219
241	XYA	0.40566	0.808219
242	ADN	0.40566	0.808219
243	FDA	0.405063	0.823529
244	CUU	0.404959	0.905405
245	V47	0.404762	0.821918
246	GSU	0.40458	0.790698
247	7MC	0.404255	0.831325
248	NSS	0.403101	0.811765
249	6FA	0.402516	0.853659
250	PPS	0.4	0.817073
251	NVA LMS	0.4	0.784091

Similar Ligands (3D)

Ligand no: 1; Ligand: NAD; Similar ligands found: 4

No:	Ligand	Similarity coefficient
1	NAD	1.0000
2	NDP	0.9403
3	TXP	0.8813
4	NZQ	0.8708

Similar Binding Sites (Proteins are less than 50% similar to leader)

Pocket No.: 1; Query (leader) PDB : 5B4T; Ligand: 3HR; Similar sites found with APoc: 210

This union binding pocket(no: 1) in the query (biounit: 5b4t.bio1) has 38 residues
No:	Leader PDB	Ligand	Sequence Similarity
1	1XSE	NDP	31.5385
2	5GT9	NAP	32.6923
3	3P19	NDP	33.0769
4	3P19	NDP	33.0769
5	3P19	NDP	33.0769
6	3P19	NDP	33.0769
7	3P19	NDP	33.0769
8	3P19	NDP	33.0769
9	4YAG	NAI	35
10	1E3W	NAD	35.7692
11	1E6W	NAD	35.7692
12	1E3W	NAD	35.7692
13	1E3W	NAD	35.7692
14	1E6W	NAD	35.7692
15	1E6W	NAD	35.7692
16	1E6W	NAD	35.7692
17	1E6W	EST	35.7692
18	1E3W	NAD	35.7692
19	3WXB	NDP	35.7692
20	3WXB	NDP	35.7692
21	5O98	NAP	36.1538
22	5O98	NAP	36.1538
23	1W8D	NAP	36.4238
24	1W73	NAP	36.4238
25	1W8D	NAP	36.4238
26	1W8D	NAP	36.4238
27	1W73	NAP	36.4238
28	1W73	NAP	36.4238
29	1W73	NAP	36.4238
30	1W8D	NAP	36.4238
31	5L53	NAP	36.5385
32	2BD0	NAP	37.2951
33	2BD0	NAP	37.2951
34	2BD0	NAP	37.2951
35	2BD0	NAP	37.2951
36	3TN7	NJP	37.3541
37	3TN7	NJP	37.3541
38	1W6U	NAP	37.4172
39	1W6U	NAP	37.4172
40	1W6U	NAP	37.4172
41	1W6U	NAP	37.4172
42	3RKR	NAP	37.6923
43	4K26	NDP	38.4615
44	2GDZ	NAD	38.8462
45	1ZBQ	NAD	38.8462
46	1XG5	NAP	39.6154
47	1XG5	NAP	39.6154
48	1XG5	NAP	39.6154
49	1XG5	NAP	39.6154
50	1N5D	NDP	40
51	1U7T	TDT	43.0769
52	1U7T	TDT	43.0769
53	2JAH	NDP	44.1296
54	2JAH	NDP	44.1296
55	2JAH	NDP	44.1296
56	2JAH	NDP	44.1296
57	5O42	9JW	44.1606
58	5O42	BGC	44.1606
59	5O42	NAD	44.1606
60	1G0N	NDP	44.6154
61	1G0N	NDP	44.6154
62	1G0N	PHH	44.6154
63	2JAP	NDP	44.9393
64	2JAP	NDP	44.9393
65	2JAP	NDP	44.9393
66	2JAP	NDP	44.9393
67	3QWI	NAP	45
68	3QWI	NAP	45
69	3QWI	CUE	45
70	3QWI	NAP	45
71	3QWI	CUE	45
72	3QWI	NAP	45
73	2DKN	NAI	45.098
74	4KWI	1TJ	45.3846
75	4KWI	NAP	45.3846
76	4KWI	1TJ	45.3846
77	4KWI	NAP	45.3846
78	6TBX	NAP	45.3846
79	5K6A	NAP	45.3846
80	6HOW	NAP	45.3846
81	5GWT	NAD	45.7692
82	5GWT	SIN	45.7692
83	5GWT	NAD	45.7692
84	5GWT	SIN	45.7692
85	5GWT	SIN	45.7692
86	5GWT	SIN	45.7692
87	5GWT	NAD	45.7692
88	5GWT	NAD	45.7692
89	1AE1	NAP	46.1538
90	1AE1	NAP	46.1538
91	1AE1	NAP	46.1538
92	1AE1	NAP	46.1538
93	3AI3	NDP	46.5385
94	3AI3	NDP	46.5385
95	3AI3	NDP	46.5385
96	3AI3	NDP	46.5385
97	5OJI	NAP	46.5385
98	3AI3	SOL	46.5385
99	3AI3	SOL	46.5385
100	5OJI	ISN	46.5385
101	5OJI	ISN	46.5385
102	5OJI	NAP	46.5385
103	3AI3	SOL	46.5385
104	3AI3	SOL	46.5385
105	6J7U	NDP	46.7433
106	4O0L	NDP	46.9231
107	4O0L	NDP	46.9231
108	4O0L	NDP	46.9231
109	4O0L	NDP	46.9231
110	6OW4	NAD	46.9231
111	6OW4	NAD	46.9231
112	6OW4	NAD	46.9231
113	6OW4	NAD	46.9231
114	6OW4	NAD	46.9231
115	6OW4	NAD	46.9231
116	6OW4	NAD	46.9231
117	6TQ5	NAP	47.1545
118	6TQ5	NAP	47.1545
119	6TQ5	NAP	47.1545
120	6TQ5	NAP	47.1545
121	3OID	NDP	47.2868
122	3OID	NDP	47.2868
123	3OID	NDP	47.2868
124	3OID	NDP	47.2868
125	3VZS	NAP	47.4708
126	2AE2	PTO	47.6923
127	2AE2	NAP	47.6923
128	2AE2	PTO	47.6923
129	2AE2	NAP	47.6923
130	2AE2	NAP	47.6923
131	2AE2	NAP	47.6923
132	2AE2	PTO	47.6923
133	2AE2	PTO	47.6923
134	2AE2	PTO	47.6923
135	2AE2	NAP	47.6923
136	2AE2	PTO	47.6923
137	2AE2	NAP	47.6923
138	5EJ2	NAD	48.0769
139	5EJ2	NAD	48.0769
140	5EJ2	NAD	48.0769
141	5EJ2	NAD	48.0769
142	2EWM	NAD	48.1928
143	2EWM	NAD	48.1928
144	6Y4D	NAP	48.249
145	6Y4D	NAP	48.249
146	4ITU	NAI	48.3271
147	4ITU	NAI	48.3271
148	4ITU	NAI	48.3271
149	4ITU	NAI	48.3271
150	4CQM	NAP	48.4615
151	4CQM	NAP	48.4615
152	4CQM	NAP	48.4615
153	4CQM	NAP	48.4615
154	4CQM	NAP	48.4615
155	4CQM	NAP	48.4615
156	4CQM	NAP	48.4615
157	5THQ	NDP	48.4615
158	5THQ	NDP	48.4615
159	5THQ	NDP	48.4615
160	5THQ	NDP	48.4615
161	2B4Q	NAP	48.4615
162	4CQM	NAP	48.4615
163	4CQM	NAP	48.4615
164	4CQM	NAP	48.4615
165	4CQM	NAP	48.4615
166	4CQM	NAP	48.4615
167	1PR9	NAP	49.1803
168	1PR9	NAP	49.1803
169	1PR9	NAP	49.1803
170	1PR9	NAP	49.1803
171	3D3W	NAP	49.1803
172	3D3W	NAP	49.1803
173	3D3W	NAP	49.1803
174	4QED	NAP	49.1936
175	4QED	NAP	49.1936
176	4QED	NAP	49.1936
177	4QED	NAP	49.1936
178	4QED	NAP	49.1936
179	4QED	NAP	49.1936
180	5OVL	NAP	49.2308
181	5OVL	NAP	49.2308
182	5OVL	NAP	49.2308
183	5OVL	NAP	49.2308
184	6CI9	NAP	49.4208
185	6CI9	NAP	49.4208
186	6CI9	NAP	49.4208
187	6CI9	NAP	49.4208
188	6CI9	NAP	49.4208
189	6CI9	NAP	49.4208
190	6CI9	NAP	49.4208
191	6CI9	NAP	49.4208
192	6CI9	NAP	49.4208
193	6CI9	NAP	49.4208
194	6CI9	NAP	49.4208
195	6CI9	NAP	49.4208
196	6CI9	NAP	49.4208
197	6CI9	NAP	49.4208
198	6CI9	NAP	49.4208
199	3A28	NAD	49.6124
200	3A28	NAD	49.6124
201	3A28	NAD	49.6124
202	3A28	NAD	49.6124
203	3A28	NAD	49.6124
204	3A28	NAD	49.6124
205	3A28	NAD	49.6124
206	3A28	NAD	49.6124
207	1NFQ	NAI	49.6154
208	1NFQ	NAI	49.6154
209	1NFQ	NAI	49.6154
210	1NFQ	NAI	49.6154
211	4FN4	NAD	50
212	4FN4	NAD	50
213	4FN4	NAD	50
214	4FN4	NAD	50
215	5T2U	NAP	50
216	5T2U	NAP	50
217	5T2U	NAP	50
218	5T2U	NAP	50

Pocket No.: 2; Query (leader) PDB : 5B4T; Ligand: 3HR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 2) in the query (biounit: 5b4t.bio1) has 38 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 3; Query (leader) PDB : 5B4T; Ligand: 3HR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 3) in the query (biounit: 5b4t.bio1) has 38 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 4; Query (leader) PDB : 5B4T; Ligand: 3HR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 4) in the query (biounit: 5b4t.bio1) has 38 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 5; Query (leader) PDB : 5B4T; Ligand: NAD; Similar sites found with APoc: 210

This union binding pocket(no: 5) in the query (biounit: 5b4t.bio1) has 38 residues
No:	Leader PDB	Ligand	Sequence Similarity
1	1XSE	NDP	31.5385
2	5GT9	NAP	32.6923
3	3P19	NDP	33.0769
4	3P19	NDP	33.0769
5	3P19	NDP	33.0769
6	3P19	NDP	33.0769
7	3P19	NDP	33.0769
8	3P19	NDP	33.0769
9	4YAG	NAI	35
10	1E3W	NAD	35.7692
11	1E6W	NAD	35.7692
12	1E3W	NAD	35.7692
13	1E3W	NAD	35.7692
14	1E6W	NAD	35.7692
15	1E6W	NAD	35.7692
16	1E6W	NAD	35.7692
17	1E6W	EST	35.7692
18	1E3W	NAD	35.7692
19	3WXB	NDP	35.7692
20	3WXB	NDP	35.7692
21	5O98	NAP	36.1538
22	5O98	NAP	36.1538
23	1W8D	NAP	36.4238
24	1W73	NAP	36.4238
25	1W8D	NAP	36.4238
26	1W8D	NAP	36.4238
27	1W73	NAP	36.4238
28	1W73	NAP	36.4238
29	1W73	NAP	36.4238
30	1W8D	NAP	36.4238
31	5L53	NAP	36.5385
32	2BD0	NAP	37.2951
33	2BD0	NAP	37.2951
34	2BD0	NAP	37.2951
35	2BD0	NAP	37.2951
36	3TN7	NJP	37.3541
37	3TN7	NJP	37.3541
38	1W6U	NAP	37.4172
39	1W6U	NAP	37.4172
40	1W6U	NAP	37.4172
41	1W6U	NAP	37.4172
42	3RKR	NAP	37.6923
43	4K26	NDP	38.4615
44	2GDZ	NAD	38.8462
45	1ZBQ	NAD	38.8462
46	1XG5	NAP	39.6154
47	1XG5	NAP	39.6154
48	1XG5	NAP	39.6154
49	1XG5	NAP	39.6154
50	1N5D	NDP	40
51	1U7T	TDT	43.0769
52	1U7T	TDT	43.0769
53	2JAH	NDP	44.1296
54	2JAH	NDP	44.1296
55	2JAH	NDP	44.1296
56	2JAH	NDP	44.1296
57	5O42	9JW	44.1606
58	5O42	BGC	44.1606
59	5O42	NAD	44.1606
60	1G0N	NDP	44.6154
61	1G0N	NDP	44.6154
62	1G0N	PHH	44.6154
63	2JAP	NDP	44.9393
64	2JAP	NDP	44.9393
65	2JAP	NDP	44.9393
66	2JAP	NDP	44.9393
67	3QWI	NAP	45
68	3QWI	NAP	45
69	3QWI	CUE	45
70	3QWI	NAP	45
71	3QWI	CUE	45
72	3QWI	NAP	45
73	2DKN	NAI	45.098
74	4KWI	1TJ	45.3846
75	4KWI	NAP	45.3846
76	4KWI	1TJ	45.3846
77	4KWI	NAP	45.3846
78	6TBX	NAP	45.3846
79	5K6A	NAP	45.3846
80	6HOW	NAP	45.3846
81	5GWT	NAD	45.7692
82	5GWT	SIN	45.7692
83	5GWT	NAD	45.7692
84	5GWT	SIN	45.7692
85	5GWT	SIN	45.7692
86	5GWT	SIN	45.7692
87	5GWT	NAD	45.7692
88	5GWT	NAD	45.7692
89	1AE1	NAP	46.1538
90	1AE1	NAP	46.1538
91	1AE1	NAP	46.1538
92	1AE1	NAP	46.1538
93	3AI3	NDP	46.5385
94	3AI3	NDP	46.5385
95	3AI3	NDP	46.5385
96	3AI3	NDP	46.5385
97	5OJI	NAP	46.5385
98	3AI3	SOL	46.5385
99	3AI3	SOL	46.5385
100	5OJI	ISN	46.5385
101	5OJI	ISN	46.5385
102	5OJI	NAP	46.5385
103	3AI3	SOL	46.5385
104	3AI3	SOL	46.5385
105	6J7U	NDP	46.7433
106	4O0L	NDP	46.9231
107	4O0L	NDP	46.9231
108	4O0L	NDP	46.9231
109	4O0L	NDP	46.9231
110	6OW4	NAD	46.9231
111	6OW4	NAD	46.9231
112	6OW4	NAD	46.9231
113	6OW4	NAD	46.9231
114	6OW4	NAD	46.9231
115	6OW4	NAD	46.9231
116	6OW4	NAD	46.9231
117	6TQ5	NAP	47.1545
118	6TQ5	NAP	47.1545
119	6TQ5	NAP	47.1545
120	6TQ5	NAP	47.1545
121	3OID	NDP	47.2868
122	3OID	NDP	47.2868
123	3OID	NDP	47.2868
124	3OID	NDP	47.2868
125	3VZS	NAP	47.4708
126	2AE2	PTO	47.6923
127	2AE2	NAP	47.6923
128	2AE2	PTO	47.6923
129	2AE2	NAP	47.6923
130	2AE2	NAP	47.6923
131	2AE2	NAP	47.6923
132	2AE2	PTO	47.6923
133	2AE2	PTO	47.6923
134	2AE2	PTO	47.6923
135	2AE2	NAP	47.6923
136	2AE2	PTO	47.6923
137	2AE2	NAP	47.6923
138	5EJ2	NAD	48.0769
139	5EJ2	NAD	48.0769
140	5EJ2	NAD	48.0769
141	5EJ2	NAD	48.0769
142	2EWM	NAD	48.1928
143	2EWM	NAD	48.1928
144	6Y4D	NAP	48.249
145	6Y4D	NAP	48.249
146	4ITU	NAI	48.3271
147	4ITU	NAI	48.3271
148	4ITU	NAI	48.3271
149	4ITU	NAI	48.3271
150	4CQM	NAP	48.4615
151	4CQM	NAP	48.4615
152	4CQM	NAP	48.4615
153	4CQM	NAP	48.4615
154	4CQM	NAP	48.4615
155	4CQM	NAP	48.4615
156	4CQM	NAP	48.4615
157	5THQ	NDP	48.4615
158	5THQ	NDP	48.4615
159	5THQ	NDP	48.4615
160	5THQ	NDP	48.4615
161	2B4Q	NAP	48.4615
162	4CQM	NAP	48.4615
163	4CQM	NAP	48.4615
164	4CQM	NAP	48.4615
165	4CQM	NAP	48.4615
166	4CQM	NAP	48.4615
167	1PR9	NAP	49.1803
168	1PR9	NAP	49.1803
169	1PR9	NAP	49.1803
170	1PR9	NAP	49.1803
171	3D3W	NAP	49.1803
172	3D3W	NAP	49.1803
173	3D3W	NAP	49.1803
174	4QED	NAP	49.1936
175	4QED	NAP	49.1936
176	4QED	NAP	49.1936
177	4QED	NAP	49.1936
178	4QED	NAP	49.1936
179	4QED	NAP	49.1936
180	5OVL	NAP	49.2308
181	5OVL	NAP	49.2308
182	5OVL	NAP	49.2308
183	5OVL	NAP	49.2308
184	6CI9	NAP	49.4208
185	6CI9	NAP	49.4208
186	6CI9	NAP	49.4208
187	6CI9	NAP	49.4208
188	6CI9	NAP	49.4208
189	6CI9	NAP	49.4208
190	6CI9	NAP	49.4208
191	6CI9	NAP	49.4208
192	6CI9	NAP	49.4208
193	6CI9	NAP	49.4208
194	6CI9	NAP	49.4208
195	6CI9	NAP	49.4208
196	6CI9	NAP	49.4208
197	6CI9	NAP	49.4208
198	6CI9	NAP	49.4208
199	3A28	NAD	49.6124
200	3A28	NAD	49.6124
201	3A28	NAD	49.6124
202	3A28	NAD	49.6124
203	3A28	NAD	49.6124
204	3A28	NAD	49.6124
205	3A28	NAD	49.6124
206	3A28	NAD	49.6124
207	1NFQ	NAI	49.6154
208	1NFQ	NAI	49.6154
209	1NFQ	NAI	49.6154
210	1NFQ	NAI	49.6154
211	4FN4	NAD	50
212	4FN4	NAD	50
213	4FN4	NAD	50
214	4FN4	NAD	50
215	5T2U	NAP	50
216	5T2U	NAP	50
217	5T2U	NAP	50
218	5T2U	NAP	50

Pocket No.: 6; Query (leader) PDB : 5B4T; Ligand: NAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 6) in the query (biounit: 5b4t.bio1) has 38 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 7; Query (leader) PDB : 5B4T; Ligand: NAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 7) in the query (biounit: 5b4t.bio1) has 38 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 8; Query (leader) PDB : 5B4T; Ligand: NAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 8) in the query (biounit: 5b4t.bio1) has 38 residues
No:	Leader PDB	Ligand	Sequence Similarity

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