Receptor
PDB id Resolution Class Description Source Keywords
4A9K 1.81 Å EC: 2.3.1.48 BROMODOMAIN OF HUMAN CREBBP WITH N-(4-HYDROXYPHENYL)ACETAMID HOMO SAPIENS INHIBITOR HISTONE EPIGENETIC READER SIGNALING PROTEIN
Ref.: FRAGMENT-BASED DISCOVERY OF BROMODOMAIN INHIBITORS INHIBITOR BINDING MODES AND IMPLICATIONS FOR LEAD D J.MED.CHEM. V. 55 576 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO A:2198;
A:2199;
Invalid;
Invalid;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
K B:2197;
Part of Protein;
none;
submit data
39.098 K [K+]
SCN A:2201;
Invalid;
none;
submit data
58.082 C N S C(#N)...
TYL A:2200;
B:2198;
Valid;
Valid;
none;
none;
submit data
151.163 C8 H9 N O2 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6AY3 1.39 Å EC: 2.3.1.48 CREBBP BROMODOMAIN IN COMPLEX WITH CPD16 (5-(7-(DIFLUOROMETH METHYL-1H-PYRAZOL-4-YL)-3,4-DIHYDROQUINOLIN-1(2H)-YL)-N-METI NDOLE-3-CARBOXAMIDE) HOMO SAPIENS CREBBP BROMODOMAIN TRANSFERASE-TRANSFERASE INHIBITOR COMPL
Ref.: A UNIQUE APPROACH TO DESIGN POTENT AND SELECTIVE CY ADENOSINE MONOPHOSPHATE RESPONSE ELEMENT BINDING PR BINDING PROTEIN (CBP) INHIBITORS. J. MED. CHEM. V. 60 10151 2017
Members (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 64 families.
1 5NLK Kd = 0.035 uM 92E C24 H23 N3 O6 CCOc1ccc(c....
2 5MQE Kd = 4 uM PKU C6 H7 Br N2 O CNC(=O)c1c....
3 4YK0 Kd = 181 uM 098 C24 H29 N3 O5 c1ccc2c(c1....
4 5MPZ Kd = 85 uM 4I8 C9 H7 N O4 COC(=O)c1c....
5 6AXQ ic50 = 99000 nM C2Y C10 H9 N O2 COC(=O)c1c....
6 5DBM Kd = 0.35 uM 58N C17 H22 N4 O C[C@@H]1CC....
7 5LPM Kd = 2.77 uM 71Y C20 H23 Cl N2 O3 CCc1c(c([n....
8 5NRW - 96N C21 H22 N2 O2 CCc1c(c([n....
9 3P1D - MB3 C5 H9 N O CN1CCCC1=O
10 5LPJ Kd = 10.1 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
11 6FQO ic50 = 0.14 uM E2T C26 H24 N2 O6 CCOc1ccc(c....
12 4TQN Kd = 0.77 uM UL4 C18 H17 N O5 CCOc1ccc(c....
13 6FRF ic50 = 0.04 uM E3T C26 H24 N2 O5 CCOc1ccc(c....
14 5TB6 Kd = 1.53 uM 77X C15 H17 N3 O CCC(=O)N1C....
15 5MQK - QPR C11 H11 N O CC(=O)c1cn....
16 5MQG - F31 C9 H11 N O2 CC(=O)c1cc....
17 5I83 ic50 = 4.1 uM 68Y C18 H20 N2 O2 C[C@@H]1CC....
18 4A9K - TYL C8 H9 N O2 CC(=O)Nc1c....
19 5I86 ic50 = 0.53 uM 69A C18 H19 N3 O2 C[C@@H]1CC....
20 6FR0 ic50 = 0.146 uM E3H C27 H26 N2 O6 CCN1C(=O)C....
21 5NU5 Kd = 0.47 uM 99E C21 H22 N2 O4 CCc1c(c([n....
22 5LPK Kd = 3.06 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
23 5MME Kd = 1.4 uM 8Q6 C20 H21 N O6 CCOc1ccc(c....
24 5I89 ic50 = 0.033 uM 69B C21 H22 N4 O C[C@@H]1CC....
25 5NU3 Kd = 0.23 uM 99E C21 H22 N2 O4 CCc1c(c([n....
26 5OWK - 7MX C9 H10 Cl N O3 CCOC(=O)C1....
27 6AY5 ic50 = 69 nM C3V C22 H20 F2 N4 O S Cn1cc(cn1)....
28 5LPL Kd = 12 uM 71X C20 H23 Cl N2 O3 CCc1c(c([n....
29 6FQU ic50 = 2.2 uM E3B C21 H23 F2 N O2 CCOc1ccc(c....
30 6DMK - 2LL C26 H30 N4 O2 Cc1c(c(on1....
31 5MMG Kd = 0.97 uM UT0 C19 H20 N2 O4 S CCOc1ccc(c....
32 5MPN Kd = 0.085 uM YE5 C17 H16 N4 O2 CCOc1ccc(c....
33 5J0D Kd = 134 nM 6F9 C27 H35 N3 O5 CCC(=O)N1C....
34 6AY3 ic50 = 9.5 nM C3J C24 H23 F2 N5 O CNC(=O)c1c....
35 5MPK Kd = 0.003 uM 0BC C21 H18 N6 O3 S CCOc1ccc(c....
36 5CGP Kd = 0.12 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
70% Homology Family (42)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 35 families.
1 5NLK Kd = 0.035 uM 92E C24 H23 N3 O6 CCOc1ccc(c....
2 5MQE Kd = 4 uM PKU C6 H7 Br N2 O CNC(=O)c1c....
3 4YK0 Kd = 181 uM 098 C24 H29 N3 O5 c1ccc2c(c1....
4 5MPZ Kd = 85 uM 4I8 C9 H7 N O4 COC(=O)c1c....
5 6AXQ ic50 = 99000 nM C2Y C10 H9 N O2 COC(=O)c1c....
6 5DBM Kd = 0.35 uM 58N C17 H22 N4 O C[C@@H]1CC....
7 5LPM Kd = 2.77 uM 71Y C20 H23 Cl N2 O3 CCc1c(c([n....
8 5NRW - 96N C21 H22 N2 O2 CCc1c(c([n....
9 3P1D - MB3 C5 H9 N O CN1CCCC1=O
10 5LPJ Kd = 10.1 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
11 6FQO ic50 = 0.14 uM E2T C26 H24 N2 O6 CCOc1ccc(c....
12 4TQN Kd = 0.77 uM UL4 C18 H17 N O5 CCOc1ccc(c....
13 6FRF ic50 = 0.04 uM E3T C26 H24 N2 O5 CCOc1ccc(c....
14 5TB6 Kd = 1.53 uM 77X C15 H17 N3 O CCC(=O)N1C....
15 5MQK - QPR C11 H11 N O CC(=O)c1cn....
16 5MQG - F31 C9 H11 N O2 CC(=O)c1cc....
17 5I83 ic50 = 4.1 uM 68Y C18 H20 N2 O2 C[C@@H]1CC....
18 4A9K - TYL C8 H9 N O2 CC(=O)Nc1c....
19 5I86 ic50 = 0.53 uM 69A C18 H19 N3 O2 C[C@@H]1CC....
20 6FR0 ic50 = 0.146 uM E3H C27 H26 N2 O6 CCN1C(=O)C....
21 5NU5 Kd = 0.47 uM 99E C21 H22 N2 O4 CCc1c(c([n....
22 5LPK Kd = 3.06 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
23 5MME Kd = 1.4 uM 8Q6 C20 H21 N O6 CCOc1ccc(c....
24 5I89 ic50 = 0.033 uM 69B C21 H22 N4 O C[C@@H]1CC....
25 5NU3 Kd = 0.23 uM 99E C21 H22 N2 O4 CCc1c(c([n....
26 5OWK - 7MX C9 H10 Cl N O3 CCOC(=O)C1....
27 6AY5 ic50 = 69 nM C3V C22 H20 F2 N4 O S Cn1cc(cn1)....
28 5LPL Kd = 12 uM 71X C20 H23 Cl N2 O3 CCc1c(c([n....
29 6FQU ic50 = 2.2 uM E3B C21 H23 F2 N O2 CCOc1ccc(c....
30 6DMK - 2LL C26 H30 N4 O2 Cc1c(c(on1....
31 5MMG Kd = 0.97 uM UT0 C19 H20 N2 O4 S CCOc1ccc(c....
32 5MPN Kd = 0.085 uM YE5 C17 H16 N4 O2 CCOc1ccc(c....
33 5J0D Kd = 134 nM 6F9 C27 H35 N3 O5 CCC(=O)N1C....
34 6AY3 ic50 = 9.5 nM C3J C24 H23 F2 N5 O CNC(=O)c1c....
35 5MPK Kd = 0.003 uM 0BC C21 H18 N6 O3 S CCOc1ccc(c....
36 5CGP Kd = 0.12 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
37 5XXH ic50 = 6.8 uM E0D C18 H20 N2 O4 CC(=O)c1cn....
38 5W0L ic50 = 1.1 nM 9UD C27 H32 F2 N6 O2 CC(=O)N1CC....
39 5W0F ic50 = 16 nM 9U7 C25 H30 N6 O2 CC(=O)N1CC....
40 5W0E ic50 = 0.94 nM 9U4 C27 H33 F2 N7 O2 CNC(=O)N1C....
41 5W0Q ic50 = 18 uM 9UG C12 H16 N2 O2 Cc1ccc2c(c....
42 5W0I ic50 = 1.4 nM 9UA C26 H30 F2 N6 O2 CC(=O)N1CC....
50% Homology Family (389)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6JJ3 ic50 = 100 nM BS6 C23 H25 N5 O4 S CN1CCN(CC1....
2 6P05 ic50 = 5.9 nM YF2 C30 H28 N6 O3 S CCS(=O)(=O....
3 4IOO - BAE C6 H13 N O CC(C)(C)C(....
4 5I88 Kd = 250 nM 69G C20 H21 N3 O2 C/C=C/CN1C....
5 5DX4 Kd = 0.137 uM E0C C20 H17 Br N2 O4 S CCN1c2ccc(....
6 6JJB ic50 = 49.5 nM BT0 C19 H16 N2 O4 S CN1c2ccc(c....
7 3JVK Kd = 118 uM GLY GLY ALY ALA PRO ARG LYS GLN n/a n/a
8 4HBX ic50 = 1.9 uM 14X C13 H17 N3 O3 S CN1Cc2cc(c....
9 4NUE Ki = 0.15 uM NUE C19 H19 N5 O3 S Cc1cc(c(c(....
10 6SB8 Kd = 0.07 uM L45 C21 H27 N3 O5 S CCN(CC)S(=....
11 5Y94 Kd = 164 nM 8QC C16 H16 Br N3 O4 S Cc1c2cc(c(....
12 6DMJ - 53W C27 H32 N4 O3 Cc1c(c(on1....
13 4HXR ic50 = 4.1 uM 1A4 C13 H10 N2 O3 S3 c1cc(cc(c1....
14 6DML - 9BM C25 H26 N4 O4 Cc1c(c(on1....
15 5TI5 ic50 = 41 uM 7CN C16 H13 Br N2 O3 S c1cc(cc(c1....
16 6VUJ ic50 = 35.2 uM RLY C23 H30 N2 O5 S CCN(CC)S(=....
17 6X7B ic50 = 27 nM ZVP C26 H24 N4 O5 S c1cc(cnc1)....
18 4O7C ic50 = 10 uM 2RK C22 H23 N5 O C1CNCCC1C2....
19 4IOQ - BAQ C4 H7 N O C1CC(=O)NC....
20 4HXK - 1AJ C11 H11 N3 O S c1csc2c1CN....
21 6S6K Kd = 0.18 uM KXK C24 H31 N3 O5 S Cc1c2c(c([....
22 2YEL ic50 = 15.5 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
23 6RWJ Kd = 6.41 uM KLK C12 H16 N2 O2 Cc1c2c(c([....
24 6SA2 Kd = 0.08 uM L25 C22 H27 N3 O6 S Cc1c2c(c([....
25 6XV7 - O2Q C14 H13 F2 N5 Cc1nnc2n1n....
26 4BW4 ic50 = 631 nM 9B6 C22 H16 F3 N5 O4 Cc1c(c(on1....
27 4O72 ic50 = 1 uM 2R4 C25 H19 N O3 S c1ccc2c(c1....
28 5F63 Kd = 12 nM 5W2 C28 H35 Cl F N7 O3 S Cc1cnc(nc1....
29 5HLS ic50 = 0.039 uM 62G C20 H16 Cl N3 O2 Cc1c-2c(on....
30 4HBW ic50 = 4.8 uM 14Z C11 H15 N3 O3 S CCNS(=O)(=....
31 4OGI Kd = 37 nM R78 C28 H39 N7 O3 CC[C@@H]1C....
32 6WW8 - YR0 C31 H32 N6 O4 S CN(C)C(=O)....
33 5TI7 ic50 = 11 uM 7CQ C17 H19 Br N2 O4 S COc1ccc(cc....
34 4J0S ic50 = 0.382 uM 1H3 C18 H17 N O3 Cc1c(c(on1....
35 6Q3Y Kd = 54 nM HG5 C30 H38 N6 O2 CC[C@@H]1C....
36 6SAJ Kd = 0.05 uM L2Z C23 H27 N3 O6 S Cc1c2c(c([....
37 4F3I Kd = 36.1 nM 0S6 C20 H19 Cl N4 O2 S Cc1c(sc-2c....
38 4QZS Kd = 89 nM JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
39 6AFR ic50 = 70 nM 9E3 C13 H10 F N3 O c1cc2c(ccc....
40 4WIV Kd = 550 nM 3P2 C21 H23 N5 O Cc1c(c(on1....
41 6VUF ic50 = 147 uM RLV C14 H20 N2 O3 S CCCNS(=O)(....
42 3P5O Kd = 55.2 nM EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
43 4UIX ic50 = 0.00000001 M TVU C22 H24 N2 O6 S2 CN1C=C(c2c....
44 4HXS ic50 = 4.1 uM 1A3 C16 H14 N2 O3 S2 c1ccc(cc1)....
45 5HM0 ic50 = 0.44 uM 62V C18 H13 Cl N2 O Cc1c-2c(on....
46 5DLX Kd = 2 uM 5D2 C25 H33 Cl N8 O Cc1nnc2n1n....
47 5TI2 ic50 = 24 uM 7CJ C16 H15 F N2 O3 S c1cc(cc(c1....
48 5D3H Kd = 7.9 uM 57G C20 H27 N3 O6 S CCc1c(c([n....
49 6E4A Kd = 44 nM HRY C29 H34 Cl N7 O CN1C=C(C=C....
50 4MEP ic50 = 4.7 uM 24Y C19 H14 Cl N5 O Cc1cccnc1n....
51 4YH4 ic50 = 26 uM Y81 C20 H15 N3 O2 c1ccc(cc1)....
52 5D3N Kd = 9.2 uM L40 C18 H23 N3 O4 S CCc1c(c([n....
53 6C7R Kd = 2.2 nM EO4 C24 H25 N7 O2 Cc1c(c(on1....
54 6WGX ic50 = 0.15 uM U0D C31 H36 F3 N7 Cc1cc(cc(c....
55 6HOV - FER C10 H10 O4 COc1cc(ccc....
56 5D26 Kd = 0.81 uM L28 C19 H26 N4 O5 S CCc1c(c([n....
57 3MUK Kd = 380 uM ALA THR PRK ALA ALA ARG LYS SER n/a n/a
58 4J3I Kd = 8.93 uM 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
59 6X7D ic50 = 388 nM UT4 C19 H18 N2 O4 S c1cc2c(cc1....
60 4QB3 Kd = 3.4 uM 30M C17 H21 N3 O2 CC(=O)NCCC....
61 4LZS Kd = 16 uM L46 C11 H16 N2 O2 CCc1c(c([n....
62 6HDQ ic50 = 5.01 uM FZE C30 H37 F2 N5 O Cc1cc(cnc1....
63 4O71 ic50 = 18 uM CPB C21 H20 Cl N O5 C[N@]1CC[C....
64 4CFL Kd = 1.33 uM 8DQ C19 H18 N2 O2 c1ccc(cc1)....
65 4C67 - L5S C15 H12 N4 S Cc1nnc2n1-....
66 6V1K - 5SW C20 H23 N3 O3 CN1C=C(c2c....
67 4QR3 ic50 = 1.4 uM BNJ C14 H16 N2 O3 S2 c1cc(cc(c1....
68 4ZC9 - 4MW C38 H37 Cl N8 O7 S Cc1c(sc-2c....
69 4MEO - 25V C18 H16 N2 O2 Cc1cc(c2cc....
70 6UVM Kd = 510 uM QJA C11 H13 N O S2 CC(=O)N1CC....
71 4LRG ic50 = 0.026 uM 1XB C20 H18 Cl N3 O2 S Cc1c(sc-2c....
72 6CKS ic50 = 0.015 uM F5Y C23 H23 N3 O4 S CCS(=O)(=O....
73 6DJC Ki = 232.8 nM CF6 C48 H54 Cl2 N10 O2 S2 Cc1c(sc-2c....
74 5TI3 ic50 = 44 uM 7CG C16 H14 Br2 N2 O3 S c1cc(cc(c1....
75 4HXP - 1A5 C10 H10 N2 O3 c1cc(ccc1C....
76 6PSB ic50 = 24 uM Y18 C17 H19 N3 O2 CN1C[C@H](....
77 6CD4 ic50 = 5.14 uM EX1 C33 H42 N8 O3 CC(C)N1c2c....
78 4O7E ic50 = 5.7 uM 2RN C20 H15 N3 O c1ccc(cc1)....
79 4O74 ic50 = 0.025 uM R78 C28 H39 N7 O3 CC[C@@H]1C....
80 4BW2 ic50 = 6.31 uM UTH C24 H24 N4 O3 Cc1c(c(on1....
81 5CS8 ic50 = 2.29 uM EB8 C21 H18 N2 O5 S CCN1c2ccc(....
82 3U5J Kd = 2.46 uM 08H C17 H13 Cl N4 Cc1nnc2n1-....
83 5EIS Kd = 1.8 uM 5OU C14 H13 Cl N4 O2 CCn1cnc2c1....
84 6FO5 Kd = 0.19 uM DZH C25 H26 N6 O5 S CCn1cnc2c1....
85 6V1L Kd = 418 nM 5U6 C20 H23 N3 O3 CN1C=C(c2c....
86 3U5L Kd = 0.64 uM 08K C17 H14 Cl N5 Cc1nnc2n1-....
87 4QR4 ic50 = 0.25 uM BNK C14 H15 Cl N2 O3 S2 c1cc(c(cc1....
88 4O7A ic50 = 19 uM 2RF C16 H10 Cl2 N2 O3 c1cc(cc(c1....
89 5F61 Kd = 35 nM 5W0 C26 H34 F N7 O2 S Cc1cnc(nc1....
90 4HXN - 1A7 C9 H6 F N O S c1ccc(c(c1....
91 6DL2 Ki = 33 nM GUJ C17 H17 N3 O S Cc1c(c2c(s....
92 5Z5U - 96U C12 H10 N4 O2 c1cn(cn1)c....
93 5TI4 ic50 = 26 uM 7CM C16 H14 Cl F N2 O3 S c1cc(cc(c1....
94 5Y8C ic50 = 0.16 uM 8P9 C16 H15 Cl N2 O5 S Cc1c2cc(c(....
95 4NUD Ki < 0.0845 uM NUD C18 H17 N5 O3 S Cc1cc(c(cc....
96 4O7B ic50 = 20 uM 2RJ C26 H26 F N5 O Cc1cccc(c1....
97 5CPE ic50 = 0.45 uM EB2 C20 H24 N2 O3 S CCN1c2ccc(....
98 5MLI ic50 = 130 uM 82I C6 H8 Cl N3 O CNC1=C(C(=....
99 5DW2 Kd = 1.44 uM 5GD C24 H29 N3 O4 Cc1cc(cc(c....
100 5D3P Kd = 7.4 uM 57E C19 H21 N3 O4 S CCc1c(c([n....
101 4PCE ic50 = 7 uM 2N0 C17 H19 N O CCc1cc2c(n....
102 5D25 Kd = 0.46 uM 56M C19 H25 N3 O5 S CCN(CC)S(=....
103 5DLZ Kd = 1.8 uM 5D1 C28 H35 N3 O3 Cc1cccc(c1....
104 5Y8W ic50 = 0.23 uM 8PU C15 H13 Br N2 O5 S Cc1c2cc(c(....
105 4J0R ic50 = 0.386 uM 1H2 C18 H17 N O3 Cc1c(c(on1....
106 6MH7 ic50 = 1.3 uM JQY C26 H27 F N6 Cc1ccc(cc1....
107 5F60 Kd = 43 nM 5VZ C26 H34 Cl N7 O2 S Cc1cnc(nc1....
108 5Z5V ic50 = 287 nM 96X C15 H14 N4 O2 CC(=O)Nc1c....
109 4HXO - 1A6 C11 H10 N4 O S Cc1cc(on1)....
110 5CRM ic50 = 1.09 uM EB5 C15 H16 N2 O3 S CCNS(=O)(=....
111 6YQN ic50 = 0.72 uM P8T C32 H28 Cl N7 O2 S Cc1c(sc-2c....
112 5CQT Kd = 0.124 uM EB3 C19 H22 N2 O3 S CCN1c2ccc(....
113 5KHM Ki = 5.012 nM XNH C25 H33 N7 O3 C[C@@H]1C(....
114 6XV3 - O2B C28 H33 N9 O Cc1nnc2n1c....
115 4Z1S ic50 = 0.79 uM 559 C23 H21 Cl N6 Cc1nnc2n1-....
116 4MR3 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
117 5MKZ ic50 = 20 uM RNK C11 H12 Cl N3 O S Cc1ccsc1CN....
118 5ULA Ki = 77 nM 5MJ C20 H19 Cl N2 O3 CC1=C(CCC1....
119 4O78 ic50 = 4.6 uM SAV C21 H22 N6 O3 Cc1c2ccc(c....
120 6XVC - O32 C22 H21 N5 O2 Cc1nnc2n1c....
121 4OGJ Kd = 164 nM 2TA C27 H36 N6 O3 S Cc1cnc(nc1....
122 5A85 ic50 = 5.01 uM 78J C21 H30 N4 O2 CC1=Cc2ccn....
123 5TI6 ic50 = 21 uM 7CO C16 H14 F2 N2 O3 S c1cc(cc(c1....
124 6MAU - JBS C30 H32 N6 O3 Cc1c(c(on1....
125 6S4B Kd = 0.14 uM KUH C22 H29 N3 O5 S CCN(CC)S(=....
126 6Q3Z Kd = 44 nM HG8 C29 H38 N6 O2 S CC[C@@H]1C....
127 6V0U Kd = 392 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
128 6VUC ic50 = 144 uM RLS C16 H22 N2 O3 S CN1C[C@H](....
129 4MR4 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
130 4QR5 ic50 = 0.06 uM BNM C18 H21 N3 O4 S2 c1c(cc(cc1....
131 4MEQ - 25O C12 H11 N5 Cc1cc(n2c(....
132 4O77 ic50 = 2.5 uM 2RE C20 H14 F N3 O c1cc(ccc1c....
133 6XUZ - O1W C24 H33 N9 O2 Cc1nnc2n1c....
134 5EI4 ic50 = 26.4 uM 5NV C17 H17 Cl N8 O2 S CCn1c(nc2c....
135 5CY9 Kd = 0.218 uM E0A C17 H20 N2 O3 S CCCCS(=O)(....
136 6MH1 ic50 = 1.7 uM JQP C26 H27 F N6 Cc1cc(cc(c....
137 5CRZ ic50 = 0.45 uM EB7 C19 H14 Cl F N2 O3 S CCN1c2ccc(....
138 5Y93 ic50 = 2.27 uM 8Q9 C23 H27 Br N4 O7 S Cc1c2cc(c(....
139 5AD2 Kd = 63 nM ETU C24 H30 Cl N7 O2 C[C@@H]1C(....
140 4E96 ic50 = 0.22 uM 0NS C16 H17 N3 O4 S CN1Cc2cc(c....
141 5D0C Kd = 2.34 uM E0B C21 H25 N3 O4 S CCN1c2ccc(....
142 4O7F ic50 = 13 uM 2RQ C25 H24 F N5 O2 COc1ccccc1....
143 5CP5 Kd = 1.234 uM EB0 C19 H15 F N2 O3 S CCN1c2ccc(....
144 4CFK Kd = 1.83 uM LY2 C19 H17 N O3 c1ccc(cc1)....
145 5D3R - 57C C23 H31 N3 O4 S CCCc1c(c([....
146 4NUC Ki = 0.91 uM 435 C19 H18 N4 O3 S Cc1cc(cc(c....
147 4HXL ic50 = 2.2 uM 1A9 C22 H25 N3 O4 S3 c1cc(sc1)S....
148 6CIY ic50 = 0.41 uM F3J C34 H42 N8 O3 CN1CCN(CC1....
149 5D3L Kd = 0.88 uM 57F C21 H29 N3 O5 S CCc1c(c([n....
150 4A9L - P9L C14 H19 N3 O4 S CN1Cc2cc(c....
151 4XYA Kd = 1370 nM 43S C13 H8 Br N5 O c1coc2c1cc....
152 4C66 - H4C C17 H16 Cl N4 S CCc1cc2c(s....
153 6UWU ic50 ~ 70 nM QKP C27 H34 N2 O6 Cc1cc(cc(c....
154 4O76 ic50 = 0.13 uM 1M3 C26 H35 N7 O2 S Cc1cnc(nc1....
155 5LJ2 ic50 = 10 uM 6XW C25 H32 N6 O4 S CC1=Cc2c(c....
156 6CD5 - R4L C35 H44 N8 O3 CN1CCN(CC1....
157 5I80 Kd = 62 nM 67B C17 H17 N3 O2 CN1C=C(c2c....
158 4O75 ic50 = 21 uM 2RC C23 H26 F N6 O9 P CC1(C(=O)N....
159 5NNF - PHE LEU PRO HIS ALY TYR ASP VAL LYS LEU n/a n/a
160 3ZYU ic50 = 0.1 uM 1GH C23 H21 N5 O3 Cc1c(c(on1....
161 4Z1Q ic50 = 0.015 uM 558 C23 H21 Cl N6 Cc1nnc2n1-....
162 6SA3 Kd = 0.42 uM L2N C23 H30 N4 O5 S Cc1c2c(c([....
163 5IGK Kd = 41.8 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
164 5Y1Y ic50 = 0.98 uM HNQ C9 H6 N2 O3 c1cc2c(ccc....
165 5Z5T - 96R C12 H10 N4 O c1cc2c(cc(....
166 6V1U - QMG C20 H19 N3 O2 Cc1ccc(cc1....
167 5KDH Ki = 0.37 uM 6RX C18 H17 N3 O4 CCN1C2=C([....
168 4PS5 ic50 = 0.29 uM 2TA C27 H36 N6 O3 S Cc1cnc(nc1....
169 5D24 Kd = 5.8 uM L26 C18 H21 N3 O4 CCc1c(c([n....
170 5ACY Kd = 6.4 nM 9S3 C30 H35 N3 O C[C@H]1C[C....
171 5HCL ic50 = 6 mM 5Y9 C4 H9 N O CC(=O)N(C)....
172 5COI ic50 = 2.58 uM 55K C20 H22 N2 O5 S CCN1c2ccc(....
173 6UWX Kd = 290 uM QKD C12 H17 N O2 S2 CCOC(=O)N1....
174 5Y8Y Kd = 82 nM 8PX C16 H15 Br N2 O5 S Cc1c2cc(c(....
175 4HXM ic50 = 0.79 uM 1A8 C17 H17 N3 O4 S3 CCCC(=O)Nc....
176 5F62 Kd = 6.8 nM 5W1 C26 H33 Cl F N7 O2 S Cc1cnc(nc1....
177 5D3S Kd = 1.3 uM 579 C20 H24 F N3 O5 S CCc1c(c([n....
178 6YQP ic50 = 1.35 uM P8N C29 H27 Cl N6 O3 S Cc1c(sc-2c....
179 6AJX Kd = 9.1 uM HCC C15 H12 O4 c1cc(ccc1C....
180 4LYW Kd = 237 nM 21Q C20 H27 N3 O5 S CCc1c(c([n....
181 4HBV ic50 = 23 uM 15E C9 H9 Br N2 O CN1Cc2cc(c....
182 5LUU Kd = 8.63 uM 77X C15 H17 N3 O CCC(=O)N1C....
183 4YH3 ic50 = 26 uM Y80 C24 H20 N2 O3 COc1ccc(cc....
184 6AJV Kd = 9.1 uM HCC C15 H12 O4 c1cc(ccc1C....
185 6CZV ic50 = 0.23 uM FOY C17 H16 N2 O2 Cc1c(c(on1....
186 4X2I ic50 = 0.35 uM 3X0 C18 H17 Cl N4 Cc1nnc2n1-....
187 6CJ1 ic50 = 6.31 uM FND C34 H44 N8 O3 CC[C@H](C)....
188 5F5Z Kd = 86 nM 5VY C26 H35 N7 O2 S Cc1cnc(nc1....
189 6UVJ Kd = 20 uM QJ1 C11 H15 N O2 S2 COC(=O)N1C....
190 6FNX ic50 = 12.6 uM DYZ C14 H14 N4 O2 CCn1cnc2c1....
191 4HBY ic50 = 4.4 uM 13F C15 H15 N3 O3 S CN1Cc2cc(c....
192 5D3J Kd = 5.7 uM L33 C20 H27 N3 O4 S CCc1c(c([n....
193 6AJY Kd = 5.3 uM A0R C16 H14 O4 COc1ccccc1....
194 3MUL - GLY GLY BTK ALA PRO ARG LYS GLN n/a n/a
195 4LR6 ic50 = 33 uM 1XA C10 H10 N2 O Cc1c(c(on1....
196 5AD3 Kd = 7.9 nM K6K C26 H30 N10 O3 CN(CCOc1cc....
197 4PCI ic50 = 7.5 uM 2NJ C16 H16 N2 O CN1c2ccccc....
198 5D3T Kd = 12 uM 56Y C19 H23 N3 O3 CCc1c(c([n....
199 6SAH Kd = 0.26 uM L2W C23 H29 N3 O5 S Cc1c2c(c([....
200 5LJ1 ic50 > 0.0000316 M 6XX C28 H35 F2 N5 O3 Cc1cc(cnc1....
201 4O70 ic50 = 19 uM 1QK C21 H29 N6 O2 CCc1cnn2c1....
202 4XY9 Kd = 4651 nM 43U C12 H10 Br N5 O COc1ccc(cc....
203 3MXF - JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
204 5CFW Kd = 0.78 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
205 5A5S ic50 = 1.3 uM NP8 C20 H23 N5 O2 CC1=Cc2c(c....
206 4UIY ic50 = 0.00000001 M 5V2 C21 H20 F3 N3 O3 S2 CN1C=C(c2c....
207 6PS9 ic50 = 79 uM Y17 C18 H21 N3 O2 CN1C[C@@H]....
208 4LZR Kd = 20 uM LOC C22 H25 N O6 CC(=O)N[C@....
209 6PRT ic50 = 2120 uM OWA C8 H13 N O3 CN1C[C@H](....
210 4BW1 ic50 = 1.26 uM S5B C25 H25 N3 O3 Cc1c(c(on1....
211 6YQO ic50 = 4.53 uM P8Q C33 H36 Cl N7 O4 S Cc1c(sc-2c....
212 4MEN - 25K C15 H17 N5 Cc1ccc(cc1....
213 6CIS ic50 = 0.3 uM X26 C37 H48 N8 O3 CC(C)Oc1cc....
214 6CKR ic50 = 0.05 uM F5V C21 H20 N4 O3 S Cn1cc(cn1)....
215 4UIZ ic50 = 0.00001995 M N1D C22 H25 N3 O6 S2 CN1C=C(c2c....
216 5KJ0 ic50 = 130 nM 6TB C29 H41 N7 O3 CC[C@@H]1C....
217 4KV1 - THR PHE ALY SER ILE MET LYS n/a n/a
218 5EGU Kd = 1.4 uM 5NQ C23 H32 N8 O2 S CCCCc1c(nc....
219 5Y8Z ic50 = 0.62 uM 8Q3 C16 H15 Br N2 O4 S Cc1cc2c(cc....
220 6VUB ic50 = 629 uM RLG C11 H13 N O CN1C[C@H](....
221 4BW3 ic50 = 501 nM 9BM C25 H26 N4 O4 Cc1c(c(on1....
222 3U5K - 08J C18 H13 Cl F N3 Cc1ncc2n1-....
223 6FGH - 6RZ C10 H16 N2 O2 S Cc1c(cccn1....
224 6FG6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
225 6FGG Kd = 17 uM D9B C18 H20 N4 O4 CN1C=C(C=C....
226 5MGJ Kd = 51 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
227 6FGV - D9T C14 H21 N3 O2 CN1C=C(C=C....
228 6FGL ic50 = 24 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
229 5OR8 - JR4 C17 H18 F N3 O3 S Cc1cc2c(cc....
230 5FE0 - ALY C8 H16 N2 O3 CC(=O)NCCC....
231 5LVR Kd = 250 uM 78Y C10 H10 N4 O Cc1c(nn(n1....
232 5FDZ Kd = 6.8 uM 5X0 C21 H24 N2 O5 CNC(=O)c1c....
233 5FE1 - 12Q C10 H9 N O CN1c2ccccc....
234 5FE6 Kd = 6910 uM 5WZ C9 H16 N2 O C1CC1C(=O)....
235 5FE2 - 5WV C9 H9 N O CN1Cc2cccc....
236 5FE7 Kd = 488 uM 5WU C10 H14 N2 O2 Cc1c2c(n(n....
237 5FE8 - 5WT C13 H14 N2 O2 CC1=CC(=O)....
238 5FE4 - 5WY C9 H9 N O3 c1cc(c2c(c....
239 5FE9 Kd = 20.98 uM 5WS C12 H14 N2 O3 S CC1=CC(=O)....
240 5FE5 - 2QC C9 H9 N3 S c1cc(ccc1C....
241 5MKX ic50 = 20 uM 82I C6 H8 Cl N3 O CNC1=C(C(=....
242 5LVQ Kd = 73 uM 2LX C13 H17 N O3 CNC(=O)c1c....
243 5FE3 - 5WX C8 H8 N2 O2 COc1cccc2c....
244 6C7Q - EO1 C25 H23 N7 O2 Cc1c(c(on1....
245 2YEM ic50 = 15.5 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
246 5JWM ic50 = 3.09 nM 6ON C54 H66 Cl2 N10 O9 S2 Cc1c(sc-2c....
247 5UOO Ki = 1.4 nM 8FV C26 H21 N5 O2 Cc1c(c(on1....
248 3QZS Kd = 99 uM LYS GLY GLY ALA ALY ARG HIS ARG LYS VAL n/a n/a
249 3QZT - LYS GLY GLY ALA ALY ARG HIS ARG LYS VAL n/a n/a
250 5U6V ic50 = 21 nM 7WY C22 H19 Cl N6 Cc1c-2n(nn....
251 5O3A - 31P C23 H23 Cl N4 O3 CC[C@H]([C....
252 5DFD - 59E C23 H21 N5 O3 Cc1nnc2n1-....
253 5XHK - LDR C13 H9 N O c1ccc2c(c1....
254 5O3D - 9J5 C23 H23 Cl N4 O3 CC[C@H]([C....
255 6YTM Kd = 65 nM PMW C22 H25 Cl N4 O2 S CC[C@H]([C....
256 6VIY Ki = 1.1 nM QYY C27 H29 N3 O5 S CCNC(=O)c1....
257 5IG6 Kd = 213.7 uM 6B3 C27 H18 N2 O4 c1ccc2c(c1....
258 5O3G - 9J8 C25 H26 Cl N5 O2 CCNC(=O)[C....
259 4J1P Kd = 0.206 uM 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
260 5O3I - 9HN C27 H29 Cl N4 O3 Cc1nnc2n1-....
261 5UEW - 87D C20 H20 N2 O5 S CN1C=C(C(=....
262 5O3B - 9HZ C24 H23 Cl N4 O3 Cc1nnc2n1-....
263 5O3E - 9HW C23 H24 Cl N5 O2 CCNC(=O)[C....
264 3ONI - JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
265 6K04 Ki = 3.1 nM CQF C22 H21 Cl N6 Cc1nnc2n1-....
266 5O39 - 31O C22 H21 Cl N4 O3 Cc1nnc2n1-....
267 5O3H - 9HQ C23 H24 Cl N5 O2 CCNC(=O)[C....
268 5O3C - 9J2 C22 H21 Cl N4 O3 Cc1nnc2n1-....
269 4MR6 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
270 6MOA Kd = 2.5 nM JW4 C25 H22 N4 O Cc1ccc2c(c....
271 5DW1 ic50 = 0.08 uM 5GD C24 H29 N3 O4 Cc1cc(cc(c....
272 5DFC - EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
273 4MR5 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
274 5O3F - 9HT C24 H26 Cl N5 O2 CC[C@H]([C....
275 2WP1 - LYS ALA PRO ARG ALY GLN LEU ALA THR LYS n/a n/a
276 4FLP Kd = 190.1 nM JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
277 4KCX Kd = 37 uM 1QK C21 H29 N6 O2 CCc1cnn2c1....
278 4A9I - P9I C15 H13 N2 O C/C(=C/1C=....
279 4UYH ic50 = 0.00000001 M 9S3 C30 H35 N3 O C[C@H]1C[C....
280 4A9H - TVP C12 H15 N O C[C@H]1CCc....
281 4A9F - MB3 C5 H9 N O CN1CCCC1=O
282 4ALG ic50 = 0.5 uM 1GH C23 H21 N5 O3 Cc1c(c(on1....
283 2YEK ic50 = 32.5 nM EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
284 2YDW Kd = 46 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
285 4A9J - TYL C8 H9 N O2 CC(=O)Nc1c....
286 4A9M ic50 = 0.5 uM P9M C17 H22 N2 O3 S Cc1ccc(cc1....
287 4ALH - A9P C11 H11 N O Cc1c(c(on1....
288 4A9E - 3PF C9 H10 N2 O CN1Cc2cccc....
289 4A9O - A9O C12 H13 N O CCc1c(c(no....
290 4AKN ic50 = 0.79 uM S5B C25 H25 N3 O3 Cc1c(c(on1....
291 4A9N ic50 = 1.5 uM A9N C15 H16 N2 O3 S Cc1ccc(cc1....
292 4KV4 - THR PHE ALY SER ILE MET LYS n/a n/a
293 5UEZ Ki = 970 nM 89G C18 H16 N2 O3 CN1C(=O)C=....
294 6VIX Ki = 1.3 nM QYV C24 H21 F2 N3 O5 S CCNC(=O)c1....
295 5UF0 Ki = 160 uM 89J C12 H13 N3 O CNC1=CC(=O....
296 5UEU - 0S6 C20 H19 Cl N4 O2 S Cc1c(sc-2c....
297 4Z93 Kd = 44.6 nM 4LD C24 H23 N5 O2 Cc1c(c(n[n....
298 5UEY Ki = 5.1 nM 88M C22 H24 F2 N2 O5 S CCOC1=CC(=....
299 5UEX Ki = 1.5 nM 89D C24 H26 F2 N2 O5 S CCS(Nc1ccc....
300 5I8B ic50 = 0.11 uM 69F C23 H22 N2 O2 C[C@@H]1CC....
301 5I8G Kd = 0.03 uM 69E C22 H22 N6 O C[C@@H]1CC....
302 5N18 Kd = 2.1 uM 8HZ C21 H19 N3 O Cc1ccc(cc1....
303 5MLJ Ki = 1.4 nM 9ST C17 H21 Br N4 O CN1C[C@H](....
304 6J3P Kd = 105 nM B8O C21 H25 N5 O3 CN1C[C@H](....
305 6AXQ ic50 = 99000 nM C2Y C10 H9 N O2 COC(=O)c1c....
306 5DBM Kd = 0.35 uM 58N C17 H22 N4 O C[C@@H]1CC....
307 5LPM Kd = 2.77 uM 71Y C20 H23 Cl N2 O3 CCc1c(c([n....
308 5NRW - 96N C21 H22 N2 O2 CCc1c(c([n....
309 3P1D - MB3 C5 H9 N O CN1CCCC1=O
310 5LPJ Kd = 10.1 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
311 6FQO ic50 = 0.14 uM E2T C26 H24 N2 O6 CCOc1ccc(c....
312 4TQN Kd = 0.77 uM UL4 C18 H17 N O5 CCOc1ccc(c....
313 6FRF ic50 = 0.04 uM E3T C26 H24 N2 O5 CCOc1ccc(c....
314 5TB6 Kd = 1.53 uM 77X C15 H17 N3 O CCC(=O)N1C....
315 5MQK - QPR C11 H11 N O CC(=O)c1cn....
316 5MQG - F31 C9 H11 N O2 CC(=O)c1cc....
317 5I83 ic50 = 4.1 uM 68Y C18 H20 N2 O2 C[C@@H]1CC....
318 4A9K - TYL C8 H9 N O2 CC(=O)Nc1c....
319 5I86 ic50 = 0.53 uM 69A C18 H19 N3 O2 C[C@@H]1CC....
320 6FR0 ic50 = 0.146 uM E3H C27 H26 N2 O6 CCN1C(=O)C....
321 5NU5 Kd = 0.47 uM 99E C21 H22 N2 O4 CCc1c(c([n....
322 5LPK Kd = 3.06 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
323 5MME Kd = 1.4 uM 8Q6 C20 H21 N O6 CCOc1ccc(c....
324 5I89 ic50 = 0.033 uM 69B C21 H22 N4 O C[C@@H]1CC....
325 5NU3 Kd = 0.23 uM 99E C21 H22 N2 O4 CCc1c(c([n....
326 5OWK - 7MX C9 H10 Cl N O3 CCOC(=O)C1....
327 6AY5 ic50 = 69 nM C3V C22 H20 F2 N4 O S Cn1cc(cn1)....
328 5LPL Kd = 12 uM 71X C20 H23 Cl N2 O3 CCc1c(c([n....
329 6FQU ic50 = 2.2 uM E3B C21 H23 F2 N O2 CCOc1ccc(c....
330 6DMK - 2LL C26 H30 N4 O2 Cc1c(c(on1....
331 5MMG Kd = 0.97 uM UT0 C19 H20 N2 O4 S CCOc1ccc(c....
332 5MPN Kd = 0.085 uM YE5 C17 H16 N4 O2 CCOc1ccc(c....
333 5J0D Kd = 134 nM 6F9 C27 H35 N3 O5 CCC(=O)N1C....
334 6AY3 ic50 = 9.5 nM C3J C24 H23 F2 N5 O CNC(=O)c1c....
335 5MPK Kd = 0.003 uM 0BC C21 H18 N6 O3 S CCOc1ccc(c....
336 5CGP Kd = 0.12 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
337 4BJX ic50 = 22 nM 73B C25 H23 Cl N2 O3 C[C@H]1C[C....
338 4UYD ic50 = 79.4 uM V1T C10 H11 N3 O2 CN1c2ccc(c....
339 4XUB ic50 = 1.07 uM 43D C19 H18 N8 Cc1cn(nn1)....
340 4XUA ic50 = 26 uM 43C C21 H18 N6 Cc1cn(nn1)....
341 5MGF Kd = 54 uM 7MW C9 H11 N O3 CCC(=O)c1c....
342 5E9I - F60 C8 H7 N O c1cc(cc2c1....
343 6FGT - D9T C14 H21 N3 O2 CN1C=C(C=C....
344 4NRB ic50 = 38 uM 2LX C13 H17 N O3 CNC(=O)c1c....
345 6FH6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
346 5MGG - 7MU C7 H7 Cl N2 O CNC(=O)c1c....
347 5ORB - JR6 C16 H19 N3 O2 S Cn1c(c2c(n....
348 4NRC ic50 = 241 uM 2LY C8 H9 N O3 S CNC(=O)c1c....
349 6FH7 - EN2 C17 H18 F N3 O3 CN1C=C(C=C....
350 5E9K - 5KX C3 H3 Cl N2 c1cnc([nH]....
351 4NRA Kd = 65 uM 2LW C13 H13 Cl N2 O CC(=O)N1CC....
352 5MGE Kd = 87 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
353 4NR9 - ALY C8 H16 N2 O3 CC(=O)NCCC....
354 5E9L - 6AI C7 H7 N3 c1cc2cn[nH....
355 5OR9 ic50 = 88 uM JR5 C18 H21 F N4 O3 S Cn1c(c2c(n....
356 5E74 Kd = 39 uM 5KH C25 H19 F3 N2 O3 Cc1ccc(cc1....
357 5E9M - BAE C6 H13 N O CC(C)(C)C(....
358 6FGU - D9Q C13 H19 N3 O2 CN1C=C(C=C....
359 5DYX - ADE C5 H5 N5 c1[nH]c2c(....
360 5DYU - MZ0 C4 H6 N2 O c1c([nH]cn....
361 5E73 Kd = 23 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
362 7K6R - 9ST C17 H21 Br N4 O CN1C[C@H](....
363 7KDW - WCV C20 H21 N5 O C#CCNc1ncc....
364 7KDZ - WCS C22 H30 N6 O3 S CN(C)CCCOc....
365 7K6S - VYM C13 H16 N2 O c1cc2c(cc1....
366 5A7C ic50 = 0.00018 M 5D4 C10 H20 N2 O2 CC(=O)NCCC....
367 5TPX Kd = 280 nM 7H7 C21 H24 N6 Cc1nnc2n1n....
368 6MO8 - JWD C19 H17 N3 O2 Cc1c(c(on1....
369 6ONY - HWV C28 H30 F N3 O4 CCNC(=O)c1....
370 6JKE - BUX C13 H6 Cl2 N2 O4 c1cc(cc(c1....
371 6MO7 - JWA C19 H25 N3 O4 S Cc1ccc(cc1....
372 6MO9 - JVY C19 H21 N3 O3 S Cc1c(c(on1....
373 3AQA - BYH C17 H16 N4 S2 CN1c2ccccc....
374 6K05 Ki = 95.5 nM CQF C22 H21 Cl N6 Cc1nnc2n1-....
375 5WUU ic50 = 0.81 uM 7UU C18 H18 N2 O3 S CN(CCCNC1=....
376 5N17 Kd = 4.8 uM 8FK C19 H18 N2 O3 S CN1c2ccc(c....
377 5N16 Kd = 5 uM 8FN C22 H15 N5 O2 S c1ccc2c(c1....
378 6VIZ Ki = 120 nM QYY C27 H29 N3 O5 S CCNC(=O)c1....
379 6VIW Ki = 21.6 nM QYV C24 H21 F2 N3 O5 S CCNC(=O)c1....
380 5XXH ic50 = 6.8 uM E0D C18 H20 N2 O4 CC(=O)c1cn....
381 5ML0 - P2L C11 H17 Cl N4 O CN1CCC[C@H....
382 5W0L ic50 = 1.1 nM 9UD C27 H32 F2 N6 O2 CC(=O)N1CC....
383 5W0F ic50 = 16 nM 9U7 C25 H30 N6 O2 CC(=O)N1CC....
384 5W0E ic50 = 0.94 nM 9U4 C27 H33 F2 N7 O2 CNC(=O)N1C....
385 5W0Q ic50 = 18 uM 9UG C12 H16 N2 O2 Cc1ccc2c(c....
386 5W0I ic50 = 1.4 nM 9UA C26 H30 F2 N6 O2 CC(=O)N1CC....
387 5VOM ic50 = 0.79 uM 9GY C24 H23 N3 O4 C[C@H]1CN(....
388 2RI7 - ALA ARG THR MLY GLN THR ALA ARG LYS n/a n/a
389 6J3O Kd = 2.4 uM B4L C13 H19 N5 O CN1CCC[C@H....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: TYL; Similar ligands found: 6
No: Ligand ECFP6 Tc MDL keys Tc
1 TYL 1 1
2 T9V 0.529412 0.814815
3 GT4 0.5 0.631579
4 N4E 0.461538 0.733333
5 20N 0.45 0.612903
6 3E1 0.414634 0.685714
Similar Ligands (3D)
Ligand no: 1; Ligand: TYL; Similar ligands found: 1259
No: Ligand Similarity coefficient
1 AEG 0.9907
2 MSR 0.9801
3 4HP 0.9771
4 SNU 0.9722
5 HC4 0.9696
6 4FA 0.9696
7 CPZ 0.9694
8 YRL 0.9686
9 PAC 0.9677
10 PHU 0.9656
11 36Y 0.9645
12 PH3 0.9643
13 A5E 0.9639
14 TZF 0.9633
15 M4T 0.9632
16 6NT 0.9627
17 OGA 0.9622
18 4BZ 0.9622
19 0HO 0.9617
20 0HN 0.9616
21 2HG 0.9613
22 AEF 0.9611
23 1F1 0.9607
24 3NY 0.9606
25 AKG 0.9605
26 3A9 0.9604
27 C1M 0.9601
28 M3H 0.9594
29 JDN 0.9594
30 I4B 0.9593
31 URS 0.9593
32 6NI 0.9588
33 ANN 0.9587
34 HHH 0.9585
35 TYR 0.9582
36 JAW 0.9582
37 GWM 0.9581
38 2HU 0.9578
39 PO6 0.9577
40 J9N 0.9576
41 4WL 0.9575
42 TYE 0.9574
43 TGX 0.9574
44 5NI 0.9573
45 DHY 0.9570
46 94W 0.9569
47 E5X 0.9569
48 2ZM 0.9566
49 F4E 0.9566
50 JB8 0.9564
51 BZ2 0.9560
52 OTR 0.9557
53 FBB 0.9550
54 ABI 0.9550
55 4ZA 0.9549
56 PHB 0.9548
57 I3E 0.9547
58 3C4 0.9546
59 S2G 0.9546
60 MQN 0.9541
61 PNZ 0.9541
62 P72 0.9540
63 HBD 0.9540
64 K2T 0.9539
65 PAB 0.9536
66 HDH 0.9532
67 4MA 0.9526
68 4P5 0.9522
69 PIM 0.9521
70 6FZ 0.9520
71 TCA 0.9518
72 4JQ 0.9516
73 PBZ 0.9514
74 2BX 0.9512
75 PIY 0.9506
76 0TU 0.9506
77 RBJ 0.9503
78 1Y6 0.9500
79 6KT 0.9488
80 268 0.9478
81 ICB 0.9478
82 4YO 0.9476
83 J9Q 0.9476
84 NPO 0.9475
85 5LA 0.9475
86 BPN 0.9472
87 AC6 0.9471
88 428 0.9471
89 0JD 0.9466
90 NYL 0.9463
91 3QM 0.9462
92 HCI 0.9461
93 DHR 0.9459
94 SN4 0.9457
95 8NB 0.9456
96 DZA 0.9455
97 J6W 0.9452
98 B40 0.9451
99 SW7 0.9451
100 ESX 0.9450
101 CWJ 0.9448
102 826 0.9448
103 2HC 0.9446
104 INO 0.9446
105 PHE 0.9444
106 GLN 0.9443
107 F4K 0.9442
108 ODO 0.9440
109 GO2 0.9436
110 9R5 0.9435
111 258 0.9432
112 2QC 0.9430
113 1M2 0.9430
114 ALE 0.9429
115 NFM 0.9428
116 AMH 0.9427
117 4BL 0.9426
118 L99 0.9424
119 HNK 0.9423
120 15N 0.9420
121 UA5 0.9419
122 173 0.9418
123 JLZ 0.9416
124 MUC 0.9415
125 HX4 0.9415
126 DHB 0.9415
127 PEA 0.9412
128 88L 0.9411
129 CXH 0.9411
130 4BY 0.9409
131 4NM 0.9408
132 2IT 0.9406
133 DGL 0.9406
134 LDP 0.9405
135 2FY 0.9396
136 3ZB 0.9391
137 174 0.9389
138 LPK 0.9389
139 E1T 0.9388
140 SNO 0.9388
141 97T 0.9387
142 BCU 0.9384
143 KTJ 0.9382
144 CXF 0.9379
145 BZ3 0.9378
146 PPY 0.9377
147 GLU 0.9376
148 XYL 0.9376
149 RB5 0.9376
150 4I8 0.9373
151 8WO 0.9373
152 1FD 0.9371
153 4PN 0.9370
154 2HO 0.9369
155 ES2 0.9368
156 259 0.9367
157 NNO 0.9366
158 K7M 0.9365
159 3BU 0.9363
160 YPN 0.9362
161 2BG 0.9362
162 DE5 0.9362
163 6TZ 0.9362
164 JZ7 0.9361
165 QMP 0.9360
166 BNL 0.9359
167 CFI 0.9359
168 Z82 0.9358
169 ESP 0.9357
170 BNF 0.9355
171 5XC 0.9355
172 FHB 0.9355
173 8OZ 0.9354
174 5OB 0.9353
175 UNJ 0.9353
176 MPV 0.9351
177 CH9 0.9351
178 4A3 0.9350
179 TPA 0.9349
180 3HM 0.9349
181 B85 0.9347
182 XIY 0.9347
183 QY9 0.9346
184 1Z6 0.9345
185 717 0.9345
186 8U3 0.9344
187 DGN 0.9342
188 9ZE 0.9341
189 ET2 0.9341
190 264 0.9340
191 PRA 0.9339
192 0BP 0.9338
193 VGD 0.9336
194 1P8 0.9335
195 CLW 0.9335
196 URO 0.9335
197 8ZE 0.9334
198 J9T 0.9334
199 GUA 0.9334
200 P81 0.9333
201 49F 0.9333
202 O45 0.9330
203 BHO 0.9328
204 93K 0.9327
205 4NC 0.9325
206 OK7 0.9323
207 H42 0.9323
208 IHB 0.9322
209 HPP 0.9319
210 HNL 0.9318
211 4TU 0.9318
212 HBA 0.9318
213 FHC 0.9317
214 OKG 0.9316
215 BPW 0.9315
216 3MB 0.9315
217 HHI 0.9315
218 HIS 0.9315
219 MS9 0.9313
220 492 0.9313
221 GVY 0.9311
222 AHC 0.9310
223 EN1 0.9309
224 HNH 0.9308
225 HIC 0.9307
226 SYC 0.9306
227 36R 0.9306
228 HPS 0.9305
229 IWT 0.9305
230 AOT 0.9304
231 7C3 0.9304
232 RAT 0.9301
233 OVM 0.9300
234 FAN 0.9297
235 52C 0.9296
236 KTA 0.9296
237 DHS 0.9295
238 XIZ 0.9295
239 4NB 0.9295
240 FBS 0.9294
241 5VM 0.9293
242 N4B 0.9292
243 4VP 0.9292
244 DHI 0.9291
245 LNR 0.9291
246 FK8 0.9289
247 GGL 0.9288
248 ISZ 0.9288
249 80G 0.9287
250 42J 0.9286
251 PPT 0.9285
252 H8N 0.9284
253 TSU 0.9283
254 L14 0.9283
255 S24 0.9279
256 HQJ 0.9279
257 XX2 0.9278
258 K34 0.9278
259 RNT 0.9274
260 CHB 0.9273
261 B3U 0.9271
262 AMS 0.9270
263 FUD 0.9270
264 069 0.9270
265 2F6 0.9269
266 N2I 0.9269
267 92K 0.9268
268 AHN 0.9268
269 FEH 0.9266
270 ABV 0.9263
271 ENO 0.9261
272 FP1 0.9261
273 RNO 0.9261
274 M4S 0.9261
275 363 0.9261
276 SAN 0.9260
277 4JC 0.9260
278 R20 0.9259
279 BSX 0.9258
280 NIZ 0.9257
281 AX7 0.9255
282 7VP 0.9254
283 9CA 0.9252
284 4J8 0.9250
285 9TW 0.9250
286 6ME 0.9250
287 92P 0.9249
288 LQ2 0.9249
289 J0Z 0.9246
290 NF3 0.9245
291 MYJ 0.9243
292 PZI 0.9243
293 S0W 0.9240
294 PMF 0.9239
295 9ON 0.9239
296 OHJ 0.9239
297 N2Z 0.9239
298 MTL 0.9237
299 MAJ 0.9236
300 EYV 0.9235
301 I1E 0.9235
302 CXP 0.9234
303 P9P 0.9234
304 DAL DAL 0.9232
305 GJZ 0.9231
306 1IT 0.9231
307 TIH 0.9230
308 795 0.9230
309 TYC 0.9229
310 C82 0.9229
311 FA0 0.9228
312 M2K 0.9228
313 4LW 0.9227
314 C2Y 0.9227
315 RA7 0.9227
316 GVG 0.9227
317 36E 0.9227
318 7MU 0.9226
319 271 0.9225
320 F9Y 0.9225
321 COU 0.9225
322 7WG 0.9225
323 A7H 0.9222
324 PEL 0.9221
325 4JT 0.9220
326 9FL 0.9220
327 FBM 0.9219
328 RNS 0.9219
329 QSB 0.9218
330 23J 0.9217
331 LFC 0.9216
332 8XL 0.9216
333 M45 0.9214
334 OW4 0.9213
335 OCH 0.9213
336 C2B 0.9212
337 5WZ 0.9212
338 NCT 0.9212
339 ALA ALA 0.9212
340 5QY 0.9212
341 AAN 0.9211
342 FBA 0.9210
343 PKU 0.9210
344 YZM 0.9208
345 15E 0.9207
346 92G 0.9206
347 HXY 0.9205
348 RUY 0.9205
349 4FS 0.9205
350 4JM 0.9204
351 45L 0.9204
352 LT1 0.9203
353 4JL 0.9203
354 GZQ 0.9202
355 NFA 0.9201
356 L22 0.9201
357 03V 0.9199
358 JAE 0.9199
359 44V 0.9198
360 DEW 0.9197
361 CFA 0.9197
362 2HQ 0.9196
363 2AQ 0.9196
364 SSC 0.9195
365 2A9 0.9195
366 BHA 0.9194
367 E4P 0.9192
368 1L5 0.9192
369 SSB 0.9192
370 ICO 0.9190
371 HA5 0.9190
372 HY1 0.9189
373 IAC 0.9189
374 BEZ 0.9188
375 1A7 0.9186
376 PBA 0.9186
377 L5V 0.9185
378 5RN 0.9184
379 X0U 0.9184
380 LLH 0.9183
381 PZM 0.9182
382 1BN 0.9182
383 JB5 0.9182
384 9FE 0.9181
385 263 0.9180
386 M4E 0.9180
387 GLY GLY 0.9180
388 B62 0.9180
389 2UB 0.9179
390 GAB 0.9178
391 P7Y 0.9176
392 PFF 0.9175
393 TTL 0.9175
394 P80 0.9173
395 KBZ 0.9172
396 2LY 0.9172
397 FCR 0.9171
398 4XF 0.9170
399 7N0 0.9169
400 KDG 0.9168
401 SRT 0.9168
402 ES5 0.9166
403 261 0.9165
404 ESI 0.9165
405 S8V 0.9164
406 TT4 0.9164
407 QBK 0.9164
408 KOJ 0.9162
409 7O4 0.9162
410 SME 0.9161
411 4M0 0.9161
412 BQ2 0.9159
413 XRG 0.9158
414 DOB 0.9157
415 K97 0.9157
416 12T 0.9156
417 0NX 0.9156
418 DI6 0.9154
419 4V2 0.9154
420 JRB 0.9153
421 D48 0.9153
422 2MI 0.9152
423 4AA 0.9152
424 HFA 0.9150
425 A7N 0.9150
426 CEE 0.9150
427 A29 0.9149
428 K4V 0.9148
429 GLO 0.9148
430 44W 0.9148
431 3PF 0.9147
432 JAH 0.9146
433 KDV 0.9146
434 RMN 0.9144
435 HSO 0.9144
436 4BF 0.9142
437 RBL 0.9142
438 YI6 0.9141
439 3HP 0.9141
440 OQC 0.9140
441 CUW 0.9140
442 DQU 0.9140
443 86L 0.9139
444 SKM 0.9135
445 R9S 0.9135
446 R8S 0.9134
447 SHA 0.9132
448 RUJ 0.9132
449 OTW 0.9132
450 4SX 0.9129
451 6RQ 0.9128
452 XHP 0.9128
453 EHM 0.9127
454 TAG 0.9126
455 4LV 0.9126
456 ORN 0.9126
457 ASC 0.9126
458 F9P 0.9125
459 PJW 0.9125
460 6SD 0.9125
461 OW7 0.9125
462 NCA 0.9124
463 AAS 0.9123
464 DTY 0.9122
465 SMN 0.9120
466 G3E 0.9119
467 3QV 0.9118
468 HF2 0.9117
469 GRO 0.9117
470 FQI 0.9115
471 NDH 0.9115
472 86J 0.9114
473 AN3 0.9114
474 2FT 0.9112
475 OOG 0.9112
476 5XB 0.9112
477 XDE 0.9111
478 3HB 0.9110
479 61M 0.9109
480 FDR 0.9109
481 X0V 0.9108
482 449 0.9108
483 JZ4 0.9107
484 EOU 0.9107
485 OMD 0.9107
486 NAG 0.9106
487 MR1 0.9106
488 5CU 0.9106
489 SHI 0.9105
490 152 0.9105
491 S0E 0.9105
492 XDK 0.9105
493 TIU 0.9102
494 PRY 0.9101
495 GDE 0.9099
496 4VY 0.9097
497 GOJ 0.9097
498 AL0 0.9097
499 Q03 0.9096
500 J5I 0.9096
501 IXW 0.9095
502 BL0 0.9094
503 PH2 0.9094
504 1LN 0.9093
505 SOR 0.9093
506 QX4 0.9093
507 DHK 0.9092
508 JFJ 0.9092
509 IV2 0.9090
510 K82 0.9089
511 VXX 0.9089
512 SPA 0.9088
513 SE2 0.9088
514 1X4 0.9086
515 R2P 0.9084
516 CCU 0.9084
517 NLE 0.9083
518 ASO 0.9083
519 2LP 0.9082
520 54Z 0.9081
521 0FO 0.9081
522 2AL 0.9080
523 3AL 0.9080
524 RSO 0.9079
525 DPN 0.9078
526 E7S 0.9076
527 Q02 0.9075
528 5GU 0.9075
529 5NU 0.9075
530 EVF 0.9074
531 PHI 0.9073
532 M6H 0.9073
533 TH7 0.9073
534 BPY 0.9072
535 4NS 0.9071
536 TMG 0.9071
537 MVN 0.9071
538 CTL 0.9071
539 BEN 0.9070
540 PBC 0.9070
541 3AB 0.9068
542 XCG 0.9066
543 GZ2 0.9064
544 CN0 0.9063
545 9RW 0.9060
546 XAZ 0.9059
547 4FH 0.9057
548 KJU 0.9057
549 FZM 0.9055
550 M5H 0.9054
551 HX3 0.9054
552 IFP 0.9054
553 PD2 0.9054
554 270 0.9054
555 LYS 0.9052
556 P92 0.9052
557 3VS 0.9052
558 E3X 0.9052
559 9NB 0.9051
560 HWD 0.9050
561 KJH 0.9050
562 DDU 0.9049
563 F31 0.9049
564 ONR 0.9048
565 ZXD 0.9048
566 S2P 0.9047
567 P9E 0.9047
568 3HG 0.9046
569 SEP 0.9046
570 OAA 0.9046
571 IPB 0.9045
572 TSR 0.9044
573 50C 0.9044
574 GF4 0.9044
575 0F9 0.9044
576 5WV 0.9043
577 X48 0.9042
578 3AE 0.9041
579 53C 0.9040
580 XUL 0.9039
581 GZL 0.9037
582 7W1 0.9037
583 EKZ 0.9035
584 SWX 0.9035
585 4XS 0.9035
586 HG3 0.9034
587 12Q 0.9034
588 XM0 0.9034
589 YTX 0.9031
590 CS2 0.9030
591 4XV 0.9030
592 JF6 0.9030
593 C53 0.9030
594 OVP 0.9030
595 OEG 0.9029
596 FBF 0.9028
597 S7J 0.9028
598 MLT 0.9028
599 7MW 0.9028
600 SKF 0.9028
601 OHP 0.9027
602 RD4 0.9026
603 KMH 0.9025
604 505 0.9024
605 8WT 0.9023
606 I3A 0.9023
607 MNN 0.9023
608 56D 0.9022
609 3VX 0.9022
610 5QX 0.9021
611 1SA 0.9021
612 3PG 0.9019
613 JBZ 0.9019
614 DJN 0.9018
615 4RU 0.9018
616 N8Y 0.9017
617 JA8 0.9017
618 8H8 0.9017
619 8NX 0.9016
620 2FX 0.9015
621 GCO 0.9015
622 XLS 0.9014
623 11C 0.9013
624 GJP 0.9013
625 WCE 0.9011
626 VC3 0.9010
627 IZC 0.9009
628 ISA 0.9008
629 MES 0.9008
630 HQT 0.9008
631 DS0 0.9007
632 LR5 0.9007
633 NVU 0.9006
634 SKA 0.9006
635 GLC 0.9003
636 PQK 0.9002
637 4CS 0.9002
638 NOK 0.9001
639 36M 0.9001
640 46P 0.9001
641 1HN 0.9001
642 HHR 0.9001
643 HMH 0.9000
644 AC0 0.9000
645 H4E 0.8998
646 3R4 0.8998
647 PPN 0.8997
648 NOJ 0.8997
649 FTV 0.8996
650 IFL 0.8996
651 B1J 0.8996
652 4NP 0.8995
653 1WC 0.8995
654 MQB 0.8993
655 LYL 0.8992
656 TSS 0.8992
657 ONH 0.8991
658 OVV 0.8991
659 COI 0.8990
660 EUE 0.8990
661 BAM 0.8990
662 N3W 0.8989
663 PDC 0.8989
664 EE8 0.8986
665 ES7 0.8986
666 DHC 0.8985
667 ZYR 0.8984
668 FA1 0.8983
669 KKN 0.8983
670 MET 0.8983
671 MXN 0.8982
672 3DM 0.8982
673 8G0 0.8982
674 2D0 0.8982
675 3YP 0.8981
676 BP7 0.8980
677 DAH 0.8980
678 2CL 0.8980
679 8GC 0.8980
680 Z5P 0.8979
681 4NZ 0.8979
682 PBN 0.8978
683 0FK 0.8978
684 YOF 0.8977
685 KYA 0.8977
686 Y3L 0.8977
687 MEQ 0.8976
688 2FQ 0.8975
689 M5E 0.8974
690 3ID 0.8974
691 DNF 0.8973
692 QUS 0.8972
693 4MB 0.8971
694 SAF 0.8971
695 LO1 0.8971
696 5RO 0.8971
697 APG 0.8971
698 D3G 0.8970
699 N91 0.8970
700 SYV 0.8969
701 8HC 0.8968
702 5FX 0.8967
703 S7S 0.8967
704 EMZ 0.8966
705 6PC 0.8966
706 1DJ 0.8964
707 MP5 0.8964
708 MZT 0.8964
709 NIO 0.8964
710 GAL 0.8964
711 11S 0.8962
712 N9J 0.8961
713 NSP 0.8961
714 DIN 0.8961
715 G2F 0.8960
716 HL4 0.8959
717 UN1 0.8957
718 SLS 0.8957
719 QBM 0.8956
720 DVQ 0.8956
721 EA1 0.8954
722 TZE 0.8952
723 ZEC 0.8952
724 RKV 0.8951
725 MAH 0.8950
726 NTN 0.8950
727 VNL 0.8950
728 KMT 0.8949
729 BTY 0.8949
730 M3P 0.8948
731 ABF 0.8947
732 QIV 0.8947
733 27B 0.8947
734 XQ0 0.8947
735 HSM 0.8945
736 PTU 0.8943
737 IF7 0.8943
738 2KA 0.8943
739 3W8 0.8942
740 BNS 0.8942
741 FOC 0.8941
742 URC 0.8941
743 MEV 0.8941
744 BEA 0.8941
745 RM1 0.8940
746 DGJ 0.8940
747 F60 0.8939
748 JG8 0.8939
749 KUF 0.8938
750 13P 0.8937
751 AES 0.8937
752 TWO 0.8936
753 6ZX 0.8934
754 FBJ 0.8933
755 2K4 0.8933
756 M1Z 0.8932
757 UNU 0.8932
758 6FB 0.8932
759 TZL 0.8932
760 5H1 0.8931
761 L03 0.8931
762 14O 0.8931
763 HHA 0.8930
764 TZM 0.8929
765 LMR 0.8929
766 ISN 0.8929
767 SYM 0.8928
768 5MI 0.8927
769 9BF 0.8926
770 3HA 0.8925
771 GP9 0.8924
772 LVD 0.8923
773 JND 0.8923
774 MRW 0.8923
775 7QS 0.8922
776 F90 0.8922
777 HJH 0.8922
778 3NT 0.8922
779 DYA 0.8922
780 4XR 0.8921
781 G3H 0.8921
782 QSH 0.8920
783 ZBT 0.8919
784 ARP 0.8918
785 KMY 0.8918
786 SS1 0.8918
787 CLU 0.8917
788 FF2 0.8917
789 AX3 0.8916
790 T9G 0.8916
791 ACA 0.8915
792 BVA 0.8915
793 E0O 0.8914
794 EXD 0.8913
795 XBT 0.8913
796 APS 0.8913
797 DMD 0.8913
798 G14 0.8913
799 HHT 0.8912
800 BGC 0.8912
801 JA5 0.8910
802 AZM 0.8908
803 R9J 0.8907
804 PRZ 0.8907
805 LSQ 0.8907
806 CWS 0.8907
807 6AI 0.8907
808 S7A 0.8906
809 SQ7 0.8906
810 2O6 0.8905
811 3OC 0.8905
812 IOS 0.8902
813 0P6 0.8902
814 BZJ 0.8902
815 PNP 0.8900
816 5HN 0.8900
817 KP6 0.8900
818 N7I 0.8900
819 8K2 0.8899
820 SQ4 0.8897
821 5JQ 0.8896
822 0W1 0.8896
823 FYU 0.8895
824 3VQ 0.8895
825 IYR 0.8894
826 FGZ 0.8894
827 W81 0.8894
828 DBH 0.8894
829 PGH 0.8893
830 CK2 0.8893
831 ASP 0.8892
832 G4D 0.8891
833 A7W 0.8891
834 BRH 0.8890
835 EOL 0.8889
836 QSC 0.8889
837 DER 0.8889
838 8W9 0.8888
839 4Z4 0.8888
840 4CM 0.8887
841 5MB 0.8887
842 7W4 0.8887
843 AEH 0.8886
844 0VT 0.8886
845 BZX 0.8886
846 VGL 0.8885
847 5OO 0.8884
848 8CM 0.8883
849 V1T 0.8882
850 BRT 0.8882
851 75K 0.8881
852 3F0 0.8881
853 LGT 0.8880
854 8TX 0.8875
855 BDP 0.8874
856 MD6 0.8874
857 5VL 0.8873
858 ZON 0.8872
859 H7Y 0.8872
860 5TY 0.8872
861 14J 0.8869
862 DEZ 0.8868
863 4HB 0.8868
864 NDG 0.8867
865 QBS 0.8867
866 3BZ 0.8867
867 FK1 0.8867
868 QIC 0.8866
869 ASN 0.8866
870 G3P 0.8866
871 344 0.8866
872 AG2 0.8864
873 LT2 0.8864
874 2K8 0.8864
875 57O 0.8864
876 DC5 0.8863
877 MMS 0.8863
878 B55 0.8862
879 3Z8 0.8862
880 SDF 0.8861
881 H4N 0.8861
882 TTY 0.8861
883 HMU 0.8861
884 ES9 0.8860
885 24B 0.8860
886 JCZ 0.8858
887 1DU 0.8857
888 EQW 0.8857
889 3M0 0.8857
890 AZ9 0.8857
891 A2G 0.8856
892 AM4 0.8856
893 68A 0.8852
894 FOM 0.8851
895 YCP 0.8851
896 1XA 0.8849
897 SD4 0.8849