Receptor
PDB id Resolution Class Description Source Keywords
4BZS 2.1 Å EC: 3.4.15.1 HUMAN ANGIOTENISN CONVERTING ENZYME N-DOMAIN IN COMPLEX WITH HOMO SAPIENS HYDROLASE ZINC METALLOPEPTIDASE ANTIHYPERTENSIVE AGENT
Ref.: INTERKINGDOM PHARMACOLOGY OF ANGIOTENSIN-I CONVERTI INHIBITOR PHOSPHONATES PRODUCED BY ACTINOMYCETES ACS MED.CHEM.LETT. V. 5 346 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG NAG G:1;
D:1;
Invalid;
Invalid;
none;
none;
submit data
408.404 n/a O=C(N...
PG4 B:1611;
Invalid;
none;
submit data
194.226 C8 H18 O5 C(COC...
PEG B:705;
B:704;
A:705;
B:703;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
106.12 C4 H10 O3 C(COC...
K26 B:1001;
A:1001;
Valid;
Valid;
none;
none;
Ki = 75 nM
535.527 C25 H34 N3 O8 P CC[C@...
CL B:702;
A:702;
Invalid;
Invalid;
none;
none;
submit data
35.453 Cl [Cl-]
P6G A:704;
Invalid;
none;
submit data
282.331 C12 H26 O7 C(COC...
ZN B:701;
A:701;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
NAG NAG BMA H:1;
E:1;
Invalid;
Invalid;
none;
none;
submit data
570.545 n/a O=C(N...
NAG FUC F:1;
C:1;
Invalid;
Invalid;
none;
none;
submit data
367.351 n/a O=C(N...
9X6 B:1612;
A:1613;
Valid;
Valid;
none;
none;
submit data
150.153 C4 H6 O4 S C(C(=...
PE4 A:703;
Invalid;
none;
submit data
354.436 C16 H34 O8 CCOCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4BXK 2.2 Å EC: 3.4.15.1 CRYSTAL STRUCTURE OF THE ANGIOTENSIN-1 CONVERTING ENZYME N-D COMPLEX WITH A DOMAIN-SPECIFIC INHIBITOR HOMO SAPIENS HYDROLASE METALLOPROTEASE PROTEASE INHIBITOR
Ref.: FRAGMENT-BASED DESIGN FOR THE DEVELOPMENT OF N-DOMA SELECTIVE ANGIOTENSIN-1 CONVERTING ENZYME INHIBITOR CLIN.SCI. V. 126 305 2014
Members (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5AMB - MET VAL GLY GLY VAL VAL ILE ALA n/a n/a
2 4CA6 Ki = 180 nM 3EF C38 H38 N3 O9 P c1ccc(cc1)....
3 2XYD Ki = 150 nM 3ES C38 H38 N3 O9 P c1ccc(cc1)....
4 6TT1 - 1IU C19 H29 N8 O5 P C[C@H](CP(....
5 4BZS Ki = 75 nM K26 C25 H34 N3 O8 P CC[C@H](C)....
6 5AMA - ASP SER n/a n/a
7 6F9R Ki = 10.6 uM D0W C25 H33 N3 O10 CC(=O)N[C@....
8 6H5X - FT8 C19 H24 N2 O4 S2 c1ccc(cc1)....
9 4UFB - LYS PRO n/a n/a
10 3NXQ - RX4 C21 H31 N4 O8 P C[C@H](C[P....
11 6F9V Ki = 171.9 nM D0Z C26 H40 N4 O9 S CS(=O)(=O)....
12 5AM9 - GLU VAL n/a n/a
13 6TT4 - FT8 C19 H24 N2 O4 S2 c1ccc(cc1)....
14 5AM8 - PHE ARG HIS ASP SER GLY TYR n/a n/a
15 6TT3 - BJ2 C18 H28 N4 O8 C[C@@H](C(....
16 4BXK Ki = 11.21 nM 1IU C19 H29 N8 O5 P C[C@H](CP(....
17 6EN6 Ki = 11.45 nM BJ2 C18 H28 N4 O8 C[C@@H](C(....
18 6EN5 Ki = 11.45 nM BJ2 C18 H28 N4 O8 C[C@@H](C(....
19 4UFA - SAC ASP n/a n/a
70% Homology Family (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5AMB - MET VAL GLY GLY VAL VAL ILE ALA n/a n/a
2 4CA6 Ki = 180 nM 3EF C38 H38 N3 O9 P c1ccc(cc1)....
3 2XYD Ki = 150 nM 3ES C38 H38 N3 O9 P c1ccc(cc1)....
4 6TT1 - 1IU C19 H29 N8 O5 P C[C@H](CP(....
5 4BZS Ki = 75 nM K26 C25 H34 N3 O8 P CC[C@H](C)....
6 5AMA - ASP SER n/a n/a
7 6F9R Ki = 10.6 uM D0W C25 H33 N3 O10 CC(=O)N[C@....
8 6H5X - FT8 C19 H24 N2 O4 S2 c1ccc(cc1)....
9 4UFB - LYS PRO n/a n/a
10 3NXQ - RX4 C21 H31 N4 O8 P C[C@H](C[P....
11 6F9V Ki = 171.9 nM D0Z C26 H40 N4 O9 S CS(=O)(=O)....
12 5AM9 - GLU VAL n/a n/a
13 6TT4 - FT8 C19 H24 N2 O4 S2 c1ccc(cc1)....
14 5AM8 - PHE ARG HIS ASP SER GLY TYR n/a n/a
15 6TT3 - BJ2 C18 H28 N4 O8 C[C@@H](C(....
16 4BXK Ki = 11.21 nM 1IU C19 H29 N8 O5 P C[C@H](CP(....
17 6EN6 Ki = 11.45 nM BJ2 C18 H28 N4 O8 C[C@@H](C(....
18 6EN5 Ki = 11.45 nM BJ2 C18 H28 N4 O8 C[C@@H](C(....
19 4UFA - SAC ASP n/a n/a
50% Homology Family (58)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5AMB - MET VAL GLY GLY VAL VAL ILE ALA n/a n/a
2 4CA6 Ki = 180 nM 3EF C38 H38 N3 O9 P c1ccc(cc1)....
3 2XYD Ki = 150 nM 3ES C38 H38 N3 O9 P c1ccc(cc1)....
4 6TT1 - 1IU C19 H29 N8 O5 P C[C@H](CP(....
5 4BZS Ki = 75 nM K26 C25 H34 N3 O8 P CC[C@H](C)....
6 5AMA - ASP SER n/a n/a
7 6F9R Ki = 10.6 uM D0W C25 H33 N3 O10 CC(=O)N[C@....
8 6H5X - FT8 C19 H24 N2 O4 S2 c1ccc(cc1)....
9 4UFB - LYS PRO n/a n/a
10 3NXQ - RX4 C21 H31 N4 O8 P C[C@H](C[P....
11 6F9V Ki = 171.9 nM D0Z C26 H40 N4 O9 S CS(=O)(=O)....
12 5AM9 - GLU VAL n/a n/a
13 6TT4 - FT8 C19 H24 N2 O4 S2 c1ccc(cc1)....
14 5AM8 - PHE ARG HIS ASP SER GLY TYR n/a n/a
15 6TT3 - BJ2 C18 H28 N4 O8 C[C@@H](C(....
16 4BXK Ki = 11.21 nM 1IU C19 H29 N8 O5 P C[C@H](CP(....
17 6EN6 Ki = 11.45 nM BJ2 C18 H28 N4 O8 C[C@@H](C(....
18 6EN5 Ki = 11.45 nM BJ2 C18 H28 N4 O8 C[C@@H](C(....
19 4UFA - SAC ASP n/a n/a
20 3ZQZ - SLC C9 H13 N O3 Se C=C(C[SeH]....
21 2X8Z Ki = 11 nM X8Z C9 H15 N O3 S C[C@H](CS)....
22 2X97 Ki = 2200 nM RX4 C21 H31 N4 O8 P C[C@H](C[P....
23 2X93 - X93 C22 H30 N2 O5 C[C@@H](C(....
24 1J36 Ki = 18 nM LPR C21 H31 N3 O5 c1ccc(cc1)....
25 2X96 Ki = 94 uM RX3 C33 H36 N3 O7 P c1ccc(cc1)....
26 5A2R - MLT C4 H6 O5 C([C@H](C(....
27 4AA1 Ki = 76 uM ASP ARG VAL TYR ILE HIS PRO PHE n/a n/a
28 2X90 - EAL C18 H24 N2 O5 C[C@@H](C(....
29 2X92 - X92 C21 H28 N2 O5 C[C@@H](C(....
30 1J37 Ki = 1.1 nM X8Z C9 H15 N O3 S C[C@H](CS)....
31 4CA8 Ki = 120 nM 3ES C38 H38 N3 O9 P c1ccc(cc1)....
32 2X8Y - FLC C6 H5 O7 C(C(=O)[O-....
33 2X94 - X94 C17 H28 N2 O5 CCC[C@@H](....
34 4CA7 Ki = 24 nM 3EF C38 H38 N3 O9 P c1ccc(cc1)....
35 4ASQ - ARG PRO PRO GLY PHE SER PRO PHE ARG n/a n/a
36 2XHM - K26 C25 H34 N3 O8 P CC[C@H](C)....
37 2X95 - X95 C27 H34 N4 O5 c1ccc(cc1)....
38 4ASR - ARG PRO PRO GLY PHE THR PRO PHE ARG n/a n/a
39 2X91 Ki = 180 nM LPR C21 H31 N3 O5 c1ccc(cc1)....
40 6F9U - D0W C25 H33 N3 O10 CC(=O)N[C@....
41 1UZF - MCO C9 H15 N O3 S C[C@H](CS)....
42 3BKK Ki = 0.83 uM KAF C28 H30 N2 O6 c1ccc(cc1)....
43 1O8A - NXA C4 H7 N O4 C[C@@H](C(....
44 2XY9 Ki = 0.65 nM 3ES C38 H38 N3 O9 P c1ccc(cc1)....
45 3L3N - LSW C27 H34 N4 O5 c1ccc(cc1)....
46 1UZE - EAL C18 H24 N2 O5 C[C@@H](C(....
47 6H5W - FT8 C19 H24 N2 O4 S2 c1ccc(cc1)....
48 4BZR - K26 C25 H34 N3 O8 P CC[C@H](C)....
49 4APH Ki = 4 uM ASP ARG VAL TYR ILE HIS PRO PHE n/a n/a
50 2YDM ic50 = 36.4 nM SLC C9 H13 N O3 Se C=C(C[SeH]....
51 1O86 - GLY C2 H5 N O2 C(C(=O)O)N
52 6F9T - D0Z C26 H40 N4 O9 S CS(=O)(=O)....
53 3BKL Ki = 0.679 uM KAW C30 H31 N3 O6 c1ccc(cc1)....
54 4CA5 Ki = 0.41 nM 3EF C38 H38 N3 O9 P c1ccc(cc1)....
55 4C2P - X8Z C9 H15 N O3 S C[C@H](CS)....
56 2OC2 Ki = 3 nM RX3 C33 H36 N3 O7 P c1ccc(cc1)....
57 6S1Z ic50 = 1.5 nM KS8 C23 H34 N O5 P c1ccc(cc1)....
58 6S1Y - KSN C10 H16 N2 O7 C(CC(=O)N[....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: K26; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 K26 1 1
2 ACE ILE TYR GLU SER LEU 0.537634 0.612903
3 JGM 0.464789 0.649123
4 LEU ALA ILE TYR SER 0.463158 0.644068
5 GLY ALA ASP ILE PHE TYR LEU ASP GLY ALA 0.412844 0.689655
Ligand no: 2; Ligand: 9X6; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 9X6 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: K26; Similar ligands found: 0
No: Ligand Similarity coefficient
Ligand no: 2; Ligand: 9X6; Similar ligands found: 462
No: Ligand Similarity coefficient
1 GUA 1.0000
2 0VT 0.9583
3 AKG 0.9575
4 DGL 0.9533
5 OEG 0.9520
6 ASN 0.9478
7 OAA 0.9457
8 SIN 0.9432
9 GLU 0.9428
10 LMR 0.9422
11 OKG 0.9415
12 URO 0.9408
13 ZGL 0.9402
14 LEU 0.9379
15 TLA 0.9374
16 MAE 0.9370
17 GLN 0.9370
18 13P 0.9351
19 ONL 0.9349
20 GPJ 0.9346
21 MLT 0.9343
22 TEO 0.9343
23 SRT 0.9342
24 PAE 0.9326
25 GPF 0.9325
26 ASP 0.9322
27 URP 0.9317
28 HTX 0.9317
29 SHF 0.9316
30 ITN 0.9310
31 6NA 0.9308
32 S2G 0.9306
33 AT3 0.9306
34 DAS 0.9303
35 URQ 0.9297
36 CCE 0.9293
37 4MV 0.9289
38 2IT 0.9286
39 GGL 0.9286
40 PGA 0.9278
41 CP 0.9277
42 DGN 0.9274
43 98J 0.9272
44 3HG 0.9270
45 3S5 0.9264
46 KMH 0.9261
47 NLE 0.9259
48 X1S 0.9252
49 9ON 0.9245
50 TAR 0.9244
51 2HG 0.9240
52 LLQ 0.9237
53 7VD 0.9228
54 IP8 0.9220
55 HIO 0.9208
56 FUM 0.9207
57 3YP 0.9200
58 CIZ 0.9197
59 9J3 0.9197
60 IXW 0.9191
61 SAT 0.9188
62 CRN 0.9186
63 PCT 0.9183
64 2AS 0.9176
65 6JN 0.9172
66 3PP 0.9169
67 HX2 0.9167
68 HPN 0.9158
69 8EW 0.9157
70 2RH 0.9155
71 PPR 0.9137
72 PGH 0.9128
73 S0H 0.9120
74 PEP 0.9119
75 3PG 0.9118
76 3OC 0.9106
77 GG6 0.9105
78 SME 0.9105
79 AG2 0.9104
80 1GP 0.9104
81 HSO 0.9102
82 3LR 0.9099
83 G3P 0.9098
84 DZA 0.9098
85 SKG 0.9097
86 OSE 0.9092
87 O7U 0.9090
88 MHO 0.9090
89 TB6 0.9087
90 IZC 0.9082
91 QDK 0.9081
92 16D 0.9079
93 7BC 0.9073
94 G3H 0.9073
95 3SL 0.9069
96 ORN 0.9067
97 HIS 0.9066
98 LYS 0.9064
99 JYD 0.9062
100 SHV 0.9061
101 ACA 0.9058
102 VAL 0.9057
103 HZP 0.9054
104 CMS 0.9053
105 HG3 0.9045
106 6M4 0.9039
107 AL0 0.9037
108 KPL 0.9036
109 PCA 0.9034
110 LER 0.9033
111 MPD 0.9033
112 DHI 0.9032
113 THE 0.9031
114 XBT 0.9030
115 PG3 0.9029
116 2CO 0.9021
117 MET 0.9019
118 IOM 0.9018
119 GP9 0.9018
120 S8V 0.9018
121 ACH 0.9017
122 NMG 0.9013
123 COI 0.9012
124 R9M 0.9008
125 SD4 0.9007
126 VAH 0.9006
127 ROR 0.9005
128 SPV 0.9004
129 49F 0.9001
130 RNS 0.8999
131 5FX 0.8997
132 AHB 0.8996
133 MAK 0.8993
134 UN1 0.8991
135 UYA 0.8990
136 1DQ 0.8987
137 GZ3 0.8986
138 HYP 0.8980
139 HL5 0.8980
140 RSF 0.8977
141 VKC 0.8975
142 284 0.8974
143 NVA 0.8972
144 FBJ 0.8972
145 40E 0.8969
146 129 0.8968
147 O8Y 0.8967
148 HGA 0.8966
149 HSE 0.8965
150 THR 0.8964
151 BEZ 0.8964
152 UY7 0.8963
153 FOM 0.8961
154 PAH 0.8961
155 0V5 0.8961
156 PEQ 0.8961
157 MAH 0.8958
158 H95 0.8957
159 ICF 0.8956
160 FBV 0.8954
161 OOG 0.8953
162 SEP 0.8952
163 I2M 0.8946
164 1SA 0.8944
165 PG0 0.8944
166 EHM 0.8942
167 ILE 0.8938
168 URA 0.8938
169 FSG 0.8930
170 RUJ 0.8928
171 LFC 0.8927
172 XYL 0.8926
173 AUD 0.8926
174 HDA 0.8923
175 RAT 0.8922
176 ICC 0.8921
177 CFI 0.8916
178 ODV 0.8914
179 1SH 0.8913
180 KIV 0.8912
181 5XB 0.8909
182 DAV 0.8907
183 FB1 0.8906
184 YIV 0.8904
185 NXA 0.8901
186 IDH 0.8900
187 T2C 0.8900
188 TSU 0.8899
189 PMB 0.8899
190 SHO 0.8899
191 SSN 0.8899
192 LEA 0.8898
193 PPV 0.8898
194 ALO 0.8894
195 M45 0.8892
196 ECE 0.8889
197 HHI 0.8889
198 XUL 0.8887
199 RBL 0.8887
200 ZBT 0.8886
201 TZL 0.8886
202 23W 0.8884
203 AKB 0.8882
204 60P 0.8881
205 650 0.8880
206 DUC 0.8879
207 MUC 0.8872
208 1PT 0.8870
209 N6C 0.8870
210 TIU 0.8865
211 DMV 0.8865
212 CYX 0.8865
213 FLA 0.8863
214 UGC 0.8863
215 MEV 0.8857
216 PSE 0.8857
217 ENV 0.8856
218 R2P 0.8855
219 2FT 0.8848
220 PAF 0.8846
221 FQI 0.8845
222 CRS 0.8843
223 FOC 0.8842
224 FB2 0.8842
225 SER 0.8838
226 XLS 0.8837
227 DAB 0.8835
228 A20 0.8832
229 GAG 0.8831
230 TIH 0.8829
231 FCN 0.8825
232 MD0 0.8824
233 2MH 0.8820
234 4JU 0.8820
235 173 0.8817
236 POP 0.8816
237 2PN 0.8815
238 9YT 0.8815
239 ABU 0.8812
240 MDN 0.8811
241 RCO 0.8811
242 TFB 0.8809
243 LNO 0.8809
244 1DV 0.8808
245 BEN 0.8808
246 MSE 0.8807
247 LTL 0.8807
248 4SD 0.8806
249 BAE 0.8805
250 HE2 0.8804
251 ARA 0.8800
252 MNM 0.8800
253 MLA 0.8798
254 3SK 0.8795
255 3PY 0.8794
256 2TQ 0.8793
257 SAL 0.8793
258 6PC 0.8792
259 CXF 0.8792
260 MEQ 0.8791
261 PRO 0.8790
262 4CS 0.8786
263 JZ9 0.8786
264 BHH 0.8786
265 RIP 0.8785
266 CXP 0.8785
267 LG3 0.8784
268 4SV 0.8783
269 GBD 0.8782
270 3U4 0.8781
271 AHN 0.8780
272 XYS 0.8778
273 CYT 0.8776
274 MLI 0.8775
275 HPA 0.8775
276 URF 0.8775
277 TNE 0.8775
278 BE2 0.8774
279 9X7 0.8773
280 3CH 0.8773
281 DMJ 0.8773
282 HCS 0.8771
283 VNJ 0.8769
284 N7P 0.8767
285 DYA 0.8766
286 1DU 0.8764
287 R67 0.8760
288 ARB 0.8757
289 MED 0.8757
290 BHO 0.8755
291 HPY 0.8754
292 ES6 0.8750
293 DTL 0.8750
294 2DR 0.8746
295 OEM 0.8746
296 26D 0.8746
297 7WG 0.8745
298 HY3 0.8745
299 5AC 0.8745
300 DFU 0.8744
301 IDM 0.8744
302 IVA 0.8744
303 69O 0.8737
304 5XA 0.8736
305 9TY 0.8736
306 AC5 0.8736
307 HGQ 0.8735
308 DEN 0.8734
309 IHG 0.8731
310 KQY 0.8731
311 IFM 0.8730
312 XYP 0.8729
313 CHT 0.8729
314 LG5 0.8727
315 RHU 0.8727
316 BZX 0.8726
317 KMT 0.8725
318 TMH 0.8724
319 6AI 0.8724
320 1P3 0.8724
321 PLQ 0.8723
322 C21 0.8718
323 SC2 0.8716
324 ADE 0.8716
325 OXQ 0.8714
326 BVF 0.8712
327 JKE 0.8711
328 0OC 0.8711
329 FCR 0.8710
330 OPE 0.8708
331 SEJ 0.8707
332 AGK 0.8706
333 YCP 0.8706
334 64K 0.8706
335 AHR 0.8704
336 PYC 0.8702
337 2K4 0.8701
338 SMN 0.8701
339 AAS 0.8701
340 5H1 0.8700
341 BTL 0.8699
342 WBU 0.8697
343 PRS 0.8694
344 7HP 0.8694
345 BAM 0.8694
346 2KT 0.8693
347 SKJ 0.8692
348 2PC 0.8692
349 NCA 0.8691
350 GAB 0.8690
351 SS2 0.8689
352 PSJ 0.8689
353 0MK 0.8688
354 PZI 0.8688
355 JBN 0.8686
356 RMN 0.8686
357 3HL 0.8684
358 14O 0.8684
359 DLY 0.8683
360 IFL 0.8681
361 DMG 0.8680
362 HBU 0.8679
363 DPR 0.8679
364 FPI 0.8677
365 51F 0.8677
366 JZ5 0.8676
367 3HR 0.8676
368 SPA 0.8675
369 XM0 0.8673
370 BZI 0.8673
371 TAU 0.8671
372 AZF 0.8670
373 8K2 0.8669
374 IND 0.8668
375 GUN 0.8668
376 NIO 0.8668
377 PZA 0.8667
378 AMC 0.8667
379 DHS 0.8667
380 OXZ 0.8666
381 F60 0.8665
382 MRZ 0.8665
383 9DG 0.8661
384 MLE 0.8659
385 XAN 0.8659
386 192 0.8656
387 2PG 0.8656
388 DXX 0.8656
389 TZC 0.8656
390 PEZ 0.8655
391 PLU 0.8655
392 IP0 0.8653
393 GRO 0.8652
394 LZ1 0.8650
395 PTO 0.8649
396 7N0 0.8649
397 NTN 0.8649
398 APG 0.8645
399 273 0.8644
400 PYG 0.8644
401 BGC 0.8643
402 F98 0.8642
403 3V4 0.8642
404 SS1 0.8635
405 HBX 0.8635
406 CYS 0.8635
407 9RW 0.8635
408 GIF 0.8635
409 MLM 0.8633
410 51R 0.8633
411 FOA 0.8633
412 1SP 0.8631
413 NBZ 0.8629
414 8OZ 0.8629
415 MAN 0.8629
416 266 0.8628
417 F05 0.8624
418 PIS 0.8624
419 3NT 0.8620
420 IQ0 0.8618
421 286 0.8617
422 5HY 0.8613
423 DBX 0.8610
424 SYN 0.8609
425 3HB 0.8609
426 POA 0.8607
427 DIR 0.8602
428 RIB 0.8602
429 BNS 0.8600
430 7A8 0.8599
431 CEJ 0.8592
432 LXC 0.8591
433 DSN 0.8588
434 ABN 0.8588
435 VGL 0.8583
436 TZE 0.8581
437 2RA 0.8574
438 FYU 0.8572
439 8X3 0.8571
440 A09 0.8570
441 23B 0.8569
442 NMJ 0.8563
443 FUL 0.8560
444 C5J 0.8560
445 SYM 0.8559
446 DBB 0.8558
447 FPY 0.8557
448 282 0.8554
449 GLY ALA 0.8553
450 HY1 0.8550
451 FBT 0.8549
452 9SE 0.8547
453 TP5 0.8543
454 K6V 0.8543
455 DFB 0.8540
456 NLP 0.8532
457 P7I 0.8532
458 OVV 0.8529
459 1MR 0.8528
460 2HE 0.8526
461 MWP 0.8526
462 53C 0.8517
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4BXK; Ligand: 1IU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4bxk.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4BXK; Ligand: 1IU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4bxk.bio2) has 35 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback