Receptor
PDB id Resolution Class Description Source Keywords
4K7O 1.98 Å NON-ENZYME: OTHER HUMAN PEROXIREDOXIN 5 WITH A FRAGMENT HOMO SAPIENS ENZYME CYTOSOL OXIDOREDUCTASE
Ref.: COMPARING BINDING MODES OF ANALOGOUS FRAGMENTS USIN FRAGMENT-BASED DRUG DESIGN: APPLICATION TO PRDX5 PLOS ONE V. 9 02300 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DMS C:201;
B:202;
A:202;
B:203;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
78.133 C2 H6 O S CS(=O...
EKZ C:202;
B:201;
A:201;
Valid;
Valid;
Valid;
none;
none;
none;
Kd = 50 uM
166.217 C10 H14 O2 CC(C)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4K7O 1.98 Å NON-ENZYME: OTHER HUMAN PEROXIREDOXIN 5 WITH A FRAGMENT HOMO SAPIENS ENZYME CYTOSOL OXIDOREDUCTASE
Ref.: COMPARING BINDING MODES OF ANALOGOUS FRAGMENTS USIN FRAGMENT-BASED DRUG DESIGN: APPLICATION TO PRDX5 PLOS ONE V. 9 02300 2014
Members (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 1HD2 - BEZ C7 H6 O2 c1ccc(cc1)....
2 4K7N Kd = 330 uM MCT C7 H8 O2 Cc1ccc(c(c....
3 4K7I Kd = 1500 uM CAQ C6 H6 O2 c1ccc(c(c1....
4 1OC3 - BEZ C7 H6 O2 c1ccc(cc1)....
5 4MMM Kd = 150 uM BP7 C12 H10 O2 c1ccc(cc1)....
6 1H4O - BEZ C7 H6 O2 c1ccc(cc1)....
7 4K7O Kd = 50 uM EKZ C10 H14 O2 CC(C)(C)c1....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 1HD2 - BEZ C7 H6 O2 c1ccc(cc1)....
2 4K7N Kd = 330 uM MCT C7 H8 O2 Cc1ccc(c(c....
3 4K7I Kd = 1500 uM CAQ C6 H6 O2 c1ccc(c(c1....
4 1OC3 - BEZ C7 H6 O2 c1ccc(cc1)....
5 4MMM Kd = 150 uM BP7 C12 H10 O2 c1ccc(cc1)....
6 1H4O - BEZ C7 H6 O2 c1ccc(cc1)....
7 4K7O Kd = 50 uM EKZ C10 H14 O2 CC(C)(C)c1....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 1HD2 - BEZ C7 H6 O2 c1ccc(cc1)....
2 4K7N Kd = 330 uM MCT C7 H8 O2 Cc1ccc(c(c....
3 4K7I Kd = 1500 uM CAQ C6 H6 O2 c1ccc(c(c1....
4 1OC3 - BEZ C7 H6 O2 c1ccc(cc1)....
5 4MMM Kd = 150 uM BP7 C12 H10 O2 c1ccc(cc1)....
6 1H4O - BEZ C7 H6 O2 c1ccc(cc1)....
7 4K7O Kd = 50 uM EKZ C10 H14 O2 CC(C)(C)c1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: EKZ; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 EKZ 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: EKZ; Similar ligands found: 1290
No: Ligand Similarity coefficient
1 X0V 0.9961
2 4SX 0.9891
3 4FH 0.9878
4 IFP 0.9850
5 SVD 0.9764
6 SAN 0.9759
7 TSU 0.9744
8 51R 0.9723
9 FBW 0.9698
10 DHB 0.9693
11 INO 0.9676
12 FBS 0.9674
13 XCZ 0.9665
14 4NC 0.9658
15 4J8 0.9643
16 UFV 0.9640
17 XXG 0.9620
18 93K 0.9618
19 NNO 0.9612
20 DBX 0.9611
21 FCR 0.9610
22 P9P 0.9605
23 MYJ 0.9603
24 AAS 0.9602
25 AMS 0.9602
26 CHB 0.9600
27 2HO 0.9597
28 4A3 0.9588
29 FHB 0.9587
30 EYK 0.9568
31 EDR 0.9557
32 3HM 0.9556
33 LNR 0.9550
34 FB2 0.9536
35 QSB 0.9529
36 9TW 0.9528
37 6M4 0.9519
38 MAJ 0.9518
39 FBV 0.9505
40 FA1 0.9504
41 IHB 0.9500
42 L99 0.9499
43 PMB 0.9492
44 RHU 0.9488
45 DHK 0.9483
46 8WO 0.9482
47 XX2 0.9480
48 E7Z 0.9451
49 3FH 0.9420
50 A13 0.9419
51 M4S 0.9417
52 BDP 0.9415
53 PEP 0.9411
54 ASC 0.9409
55 LT2 0.9409
56 ZXD 0.9405
57 QMP 0.9401
58 EXD 0.9401
59 ASO 0.9397
60 FB1 0.9394
61 F31 0.9391
62 LDP 0.9389
63 CTS 0.9385
64 A09 0.9383
65 VNL 0.9378
66 1SA 0.9377
67 1F1 0.9375
68 36E 0.9375
69 4AA 0.9373
70 PHB 0.9373
71 HBD 0.9372
72 NPO 0.9367
73 DHS 0.9365
74 KOJ 0.9365
75 3OC 0.9365
76 SKM 0.9356
77 MJ2 0.9354
78 GAB 0.9351
79 FBU 0.9344
80 3AB 0.9343
81 4CS 0.9339
82 PAB 0.9336
83 3HB 0.9324
84 3SL 0.9323
85 3PF 0.9322
86 HDH 0.9321
87 GDE 0.9321
88 OTR 0.9317
89 CN0 0.9317
90 0HO 0.9316
91 P72 0.9315
92 WCE 0.9313
93 13P 0.9311
94 1DV 0.9309
95 1Y6 0.9307
96 NMJ 0.9307
97 KTA 0.9304
98 KKN 0.9303
99 4XS 0.9303
100 PBZ 0.9301
101 JLZ 0.9300
102 ISN 0.9298
103 4XR 0.9297
104 DHY 0.9295
105 53C 0.9294
106 5WV 0.9292
107 FEH 0.9290
108 3ID 0.9290
109 3NT 0.9289
110 0HN 0.9289
111 3NY 0.9289
112 ES7 0.9287
113 AC6 0.9285
114 4JC 0.9285
115 M1A 0.9284
116 4XV 0.9283
117 WOT 0.9280
118 OVV 0.9280
119 67N 0.9279
120 4MA 0.9278
121 HPS 0.9275
122 SOE 0.9273
123 DMD 0.9272
124 MWP 0.9272
125 5NI 0.9272
126 5HN 0.9271
127 PO6 0.9269
128 173 0.9269
129 7W4 0.9267
130 6NT 0.9266
131 2ZM 0.9262
132 8GC 0.9261
133 4P5 0.9260
134 6OT 0.9259
135 2PG 0.9256
136 XSP 0.9256
137 GYE 0.9254
138 FA0 0.9252
139 FA3 0.9252
140 R8V 0.9245
141 826 0.9243
142 QSH 0.9243
143 GZ3 0.9242
144 HIS 0.9242
145 4NG 0.9240
146 2O6 0.9239
147 H42 0.9238
148 XM0 0.9237
149 FGZ 0.9235
150 SPV 0.9234
151 5NU 0.9232
152 GTQ 0.9232
153 3A9 0.9232
154 B85 0.9231
155 4M0 0.9229
156 Q02 0.9229
157 DBH 0.9228
158 RSO 0.9228
159 5QY 0.9227
160 FE DB1 0.9226
161 92K 0.9225
162 FBT 0.9220
163 4ZA 0.9218
164 DA4 0.9217
165 3HA 0.9216
166 3M0 0.9216
167 1LQ 0.9216
168 1SQ 0.9215
169 N5J 0.9215
170 RMN 0.9215
171 D48 0.9215
172 R67 0.9214
173 3F0 0.9211
174 ABI 0.9211
175 NCA 0.9210
176 VXX 0.9209
177 G3E 0.9208
178 SYV 0.9208
179 5CU 0.9207
180 7N0 0.9207
181 SAF 0.9205
182 2HU 0.9204
183 NTN 0.9202
184 2FY 0.9201
185 4Z4 0.9200
186 24W 0.9200
187 BEZ 0.9200
188 AL0 0.9199
189 PHE 0.9198
190 GWM 0.9198
191 OSE 0.9197
192 6NI 0.9197
193 Z82 0.9196
194 4WL 0.9196
195 5SG 0.9195
196 VGL 0.9194
197 NIO 0.9193
198 PAC 0.9193
199 SEP 0.9192
200 QY9 0.9192
201 Q88 0.9191
202 KBZ 0.9189
203 6FZ 0.9189
204 3BZ 0.9188
205 J9T 0.9188
206 5IQ 0.9187
207 O72 0.9187
208 EA1 0.9186
209 069 0.9186
210 GCU 0.9186
211 GTR 0.9186
212 F60 0.9185
213 KJH 0.9184
214 TTL 0.9184
215 BRT 0.9184
216 HQJ 0.9184
217 JBH 0.9181
218 174 0.9179
219 GZL 0.9179
220 23J 0.9173
221 42J 0.9172
222 JPZ 0.9172
223 12Q 0.9171
224 BGC 0.9171
225 2K4 0.9169
226 5OB 0.9169
227 QIC 0.9166
228 HX3 0.9166
229 5QX 0.9165
230 J9Q 0.9165
231 ADA 0.9164
232 5Q0 0.9163
233 TPA 0.9163
234 1NP 0.9161
235 3SK 0.9161
236 ES1 0.9160
237 6AI 0.9160
238 TWO 0.9160
239 86J 0.9159
240 BZX 0.9158
241 TLA 0.9158
242 BZ2 0.9158
243 3PG 0.9157
244 HG3 0.9157
245 7W1 0.9157
246 4YS 0.9157
247 EVF 0.9156
248 HIO 0.9155
249 PZI 0.9155
250 52C 0.9155
251 1LM 0.9153
252 HQY 0.9152
253 14O 0.9151
254 2HQ 0.9149
255 5H1 0.9149
256 PIM 0.9149
257 2C2 0.9147
258 ANN 0.9144
259 6TZ 0.9144
260 ICO 0.9143
261 EGR 0.9142
262 8OZ 0.9141
263 DOB 0.9141
264 ISZ 0.9141
265 BHO 0.9141
266 KBB 0.9140
267 6RQ 0.9140
268 DIN 0.9138
269 3U4 0.9138
270 DOR 0.9138
271 SMN 0.9137
272 COU 0.9137
273 5RG 0.9136
274 CFI 0.9135
275 SAL 0.9135
276 HQT 0.9133
277 A7W 0.9131
278 ET2 0.9131
279 5MI 0.9130
280 BHA 0.9130
281 6PC 0.9130
282 JB5 0.9129
283 J5I 0.9129
284 F05 0.9126
285 1P3 0.9125
286 54G 0.9125
287 0W8 0.9124
288 5RO 0.9123
289 4FS 0.9122
290 QUZ 0.9122
291 ES6 0.9121
292 AFR 0.9121
293 5M0 0.9121
294 MRW 0.9121
295 GJZ 0.9121
296 03V 0.9120
297 XQ0 0.9120
298 JTH 0.9120
299 HFA 0.9119
300 SHA 0.9119
301 OCH 0.9119
302 2AQ 0.9119
303 MR1 0.9119
304 L5V 0.9119
305 BE2 0.9118
306 SE2 0.9118
307 AZ9 0.9116
308 HA5 0.9116
309 ORO 0.9116
310 5MB 0.9114
311 ALE 0.9113
312 XDE 0.9113
313 GLC 0.9113
314 JBK 0.9112
315 270 0.9110
316 AX7 0.9110
317 DX3 0.9110
318 0JD 0.9110
319 152 0.9110
320 ES5 0.9109
321 BZ3 0.9109
322 2A9 0.9107
323 4SV 0.9107
324 G4D 0.9107
325 E5X 0.9106
326 BCU 0.9105
327 9TZ 0.9104
328 4HM 0.9102
329 G2F 0.9102
330 DQA 0.9102
331 DGJ 0.9101
332 PBC 0.9101
333 BEN 0.9101
334 KUF 0.9098
335 7MU 0.9097
336 ES0 0.9097
337 LMR 0.9097
338 SS2 0.9096
339 CWM 0.9095
340 DNF 0.9095
341 EUG 0.9094
342 VNJ 0.9094
343 G3F 0.9094
344 SRT 0.9093
345 M0W 0.9093
346 G5V 0.9091
347 ADZ 0.9091
348 4M4 0.9090
349 V55 0.9088
350 5RN 0.9087
351 3Z8 0.9087
352 6M9 0.9085
353 IAC 0.9085
354 HF2 0.9084
355 0F9 0.9084
356 PNZ 0.9084
357 QSC 0.9082
358 2CK 0.9082
359 NPY 0.9082
360 7ME 0.9082
361 Q6T 0.9082
362 9FL 0.9081
363 CWS 0.9080
364 HQD 0.9080
365 EVA 0.9080
366 FOT 0.9080
367 SJ5 0.9078
368 ADE 0.9078
369 SN4 0.9078
370 3HP 0.9077
371 C2Y 0.9076
372 5MK 0.9075
373 HPA 0.9075
374 OAA 0.9075
375 ICB 0.9074
376 MLT 0.9072
377 HH8 0.9071
378 AHR 0.9071
379 1X4 0.9070
380 PEQ 0.9070
381 IJZ 0.9070
382 BNS 0.9069
383 NIZ 0.9068
384 15N 0.9067
385 NOJ 0.9067
386 15L 0.9067
387 RNS 0.9067
388 NBZ 0.9066
389 QUS 0.9065
390 DPN 0.9065
391 11S 0.9065
392 0P6 0.9065
393 IPB 0.9065
394 PHU 0.9064
395 EOL 0.9064
396 CLW 0.9062
397 FK8 0.9062
398 1DQ 0.9062
399 HHA 0.9061
400 BAM 0.9061
401 3DO 0.9060
402 2AL 0.9060
403 LCN 0.9059
404 ABV 0.9059
405 TH7 0.9059
406 HHH 0.9058
407 TAG 0.9058
408 GLU 0.9057
409 4JQ 0.9056
410 PEZ 0.9055
411 2MI 0.9054
412 5XC 0.9053
413 4XH 0.9053
414 8WT 0.9053
415 3IT 0.9052
416 H7Y 0.9051
417 ODO 0.9051
418 SKA 0.9051
419 82I 0.9051
420 ES9 0.9051
421 717 0.9050
422 X05 0.9050
423 7B4 0.9050
424 SS1 0.9050
425 AMH 0.9050
426 36R 0.9049
427 ROI 0.9049
428 D1X 0.9049
429 MSR 0.9049
430 UNC 0.9047
431 IF7 0.9046
432 PZA 0.9045
433 8U3 0.9045
434 GVG 0.9045
435 XIY 0.9043
436 BE7 0.9041
437 9EW 0.9041
438 GUN 0.9041
439 3MB 0.9041
440 FAN 0.9041
441 AEH 0.9040
442 UNU 0.9040
443 40E 0.9039
444 R2P 0.9039
445 OXC 0.9039
446 6CS 0.9039
447 0N7 0.9039
448 HCI 0.9039
449 RAT 0.9038
450 3C4 0.9037
451 2LY 0.9037
452 M0Q 0.9037
453 8CM 0.9036
454 I3A 0.9036
455 I1E 0.9035
456 TYL 0.9035
457 ASN 0.9032
458 OW4 0.9032
459 JAE 0.9032
460 7WR 0.9032
461 M4T 0.9031
462 0RW 0.9031
463 9MG 0.9031
464 HLR 0.9030
465 IP0 0.9030
466 BEA 0.9028
467 K7M 0.9027
468 15E 0.9027
469 XX3 0.9026
470 CXF 0.9026
471 M6N 0.9025
472 URC 0.9025
473 258 0.9024
474 OVM 0.9024
475 2EC 0.9023
476 AC0 0.9022
477 IFL 0.9021
478 7NI 0.9020
479 PIY 0.9020
480 HC4 0.9020
481 1P7 0.9019
482 XYP 0.9019
483 ES2 0.9018
484 9RW 0.9018
485 HBA 0.9018
486 4HC 0.9018
487 4P0 0.9018
488 MUC 0.9017
489 97T 0.9016
490 SX1 0.9015
491 8ZE 0.9014
492 APG 0.9013
493 4ZE 0.9013
494 COI 0.9012
495 H4E 0.9012
496 KJU 0.9012
497 NOY 0.9011
498 92P 0.9011
499 12T 0.9011
500 PE0 0.9011
501 34D 0.9011
502 MS9 0.9010
503 JBE 0.9010
504 7HP 0.9009
505 7VS 0.9009
506 F4E 0.9008
507 9DG 0.9008
508 SVN 0.9007
509 DGN 0.9006
510 JKE 0.9006
511 2HC 0.9005
512 Q24 0.9005
513 TIU 0.9005
514 SYG 0.9005
515 FK1 0.9004
516 CPZ 0.9004
517 10L 0.9003
518 SNU 0.9002
519 KJY 0.9000
520 FBM 0.8999
521 ESX 0.8999
522 BPN 0.8998
523 B62 0.8998
524 IOS 0.8998
525 SKF 0.8997
526 PBA 0.8997
527 4JT 0.8997
528 T9G 0.8997
529 S7J 0.8996
530 A29 0.8994
531 HMH 0.8994
532 9ZE 0.8993
533 AQO 0.8993
534 GCB 0.8992
535 F9P 0.8992
536 R9S 0.8991
537 6MP 0.8990
538 F0J 0.8989
539 JDN 0.8988
540 IV2 0.8988
541 5VM 0.8987
542 H4N 0.8987
543 ASP 0.8987
544 GCS 0.8987
545 8S0 0.8987
546 1WD 0.8986
547 7HQ 0.8986
548 VOH 0.8985
549 CTL 0.8985
550 NVU 0.8985
551 S0E 0.8985
552 3YP 0.8985
553 1DJ 0.8985
554 N3W 0.8985
555 ESI 0.8985
556 4LR 0.8984
557 PXL 0.8984
558 1P8 0.8984
559 MUA 0.8983
560 URF 0.8983
561 ONR 0.8981
562 9DA 0.8981
563 JB8 0.8981
564 NDH 0.8981
565 4YO 0.8981
566 9CA 0.8980
567 YCP 0.8980
568 DS0 0.8980
569 OMD 0.8980
570 TDR 0.8979
571 HXX 0.8979
572 GP9 0.8978
573 FBF 0.8977
574 G3P 0.8977
575 G3H 0.8977
576 UEG 0.8977
577 4HP 0.8977
578 XAN 0.8976
579 2HG 0.8975
580 MEW 0.8975
581 6DP 0.8975
582 SWA 0.8974
583 J9W 0.8974
584 WBU 0.8972
585 4NM 0.8970
586 1IT 0.8970
587 9HX 0.8970
588 5DI 0.8970
589 M58 0.8970
590 SWD 0.8968
591 GAL 0.8968
592 4ME 0.8968
593 9FE 0.8967
594 GLA 0.8965
595 M1Q 0.8965
596 GRO 0.8964
597 AW5 0.8964
598 TSS 0.8964
599 GLN 0.8963
600 JFJ 0.8963
601 TZF 0.8963
602 HHI 0.8962
603 32X 0.8962
604 NCT 0.8961
605 0V5 0.8961
606 KT7 0.8961
607 MQN 0.8961
608 TOF 0.8960
609 E4P 0.8959
610 DYA 0.8958
611 GUA 0.8958
612 42C 0.8957
613 7WV 0.8956
614 ARP 0.8955
615 259 0.8954
616 3AL 0.8953
617 TGX 0.8953
618 J9N 0.8953
619 R20 0.8952
620 GXY 0.8952
621 8XL 0.8951
622 4VY 0.8950
623 CXP 0.8949
624 0TU 0.8949
625 M1E 0.8948
626 JRB 0.8947
627 5B1 0.8946
628 0FN 0.8946
629 428 0.8946
630 IGA 0.8945
631 4FA 0.8944
632 AZG 0.8944
633 AEF 0.8944
634 G6D 0.8944
635 I3E 0.8943
636 OHP 0.8943
637 YRL 0.8943
638 3QM 0.8943
639 9PY 0.8943
640 4BZ 0.8941
641 NHG 0.8941
642 DYT 0.8940
643 6AP 0.8940
644 LZ1 0.8940
645 AZ8 0.8940
646 FBB 0.8939
647 M1H 0.8939
648 AKG 0.8939
649 FP1 0.8938
650 RM1 0.8938
651 34A 0.8938
652 9RH 0.8937
653 7WA 0.8937
654 MXN 0.8936
655 XBZ 0.8936
656 2BG 0.8934
657 OA3 0.8934
658 0LH 0.8933
659 AEG 0.8933
660 3BU 0.8932
661 39O 0.8932
662 OGA 0.8932
663 DBJ 0.8931
664 HNK 0.8930
665 149 0.8930
666 JAW 0.8930
667 1M2 0.8930
668 3WA 0.8930
669 DAL DAL 0.8929
670 5JQ 0.8926
671 DX4 0.8926
672 4NZ 0.8926
673 25W 0.8926
674 MT0 0.8925
675 141 0.8925
676 2D0 0.8925
677 5GU 0.8924
678 GAF 0.8924
679 LAO 0.8924
680 PA1 0.8924
681 IND 0.8923
682 0R1 0.8923
683 3AE 0.8921
684 MNN 0.8920
685 L7T 0.8920
686 DHQ 0.8920
687 X09 0.8920
688 BP1 0.8920
689 SG2 0.8920
690 LYL 0.8919
691 RNT 0.8919
692 4VP 0.8919
693 L3Q 0.8918
694 TYE 0.8918
695 5XB 0.8917
696 LR5 0.8917
697 UNJ 0.8917
698 LXC 0.8917
699 RJY 0.8916
700 2YU 0.8916
701 K2T 0.8915
702 MPI 0.8915
703 HLZ 0.8913
704 MCT 0.8912
705 H62 0.8912
706 E1T 0.8911
707 M5K 0.8911
708 PGH 0.8911
709 DEN 0.8911
710 0W1 0.8911
711 PC 0.8909
712 KBG 0.8909
713 9R5 0.8908
714 BZI 0.8908
715 N8Y 0.8907
716 ALL 0.8907
717 PM6 0.8907
718 2H5 0.8907
719 BZF 0.8906
720 CH9 0.8906
721 6ME 0.8905
722 7WG 0.8905
723 PRZ 0.8905
724 BTY 0.8904
725 NQ 0.8904
726 5UC 0.8904
727 S24 0.8903
728 1PT 0.8903
729 HKD 0.8902
730 0OC 0.8902
731 HH5 0.8902
732 7MX 0.8901
733 QOS 0.8901
734 2ZV 0.8901
735 JZ7 0.8900
736 6GU 0.8900
737 HJP 0.8900
738 5LA 0.8900
739 61M 0.8900
740 44V 0.8899
741 AZA 0.8899
742 AKH 0.8898
743 EUE 0.8898
744 G2H 0.8897
745 BDF 0.8897
746 DHI 0.8895
747 B57 0.8895
748 DAS 0.8894
749 TH0 0.8894
750 8NY 0.8894
751 DHR 0.8894
752 2FG 0.8893
753 OVP 0.8893
754 TEO 0.8893
755 PCA 0.8893
756 SIF 0.8890
757 HQ9 0.8890
758 VGD 0.8890
759 4JL 0.8890
760 KVP 0.8889
761 P9E 0.8889
762 FBA 0.8889
763 PYQ 0.8889
764 AJV 0.8888
765 GVH 0.8888
766 1GN 0.8887
767 24B 0.8887
768 5NS 0.8887
769 TSR 0.8885
770 GXL 0.8885
771 IDM 0.8885
772 S2G 0.8884
773 AJ2 0.8884
774 3XX 0.8884
775 IFM 0.8883
776 N2I 0.8882
777 C2U 0.8881
778 75K 0.8880
779 HL5 0.8879
780 FYU 0.8879
781 Z5P 0.8878
782 ZZZ 0.8878
783 TAR 0.8878
784 ICF 0.8877
785 ES4 0.8877
786 2IT 0.8876
787 GIV 0.8876
788 37T 0.8875
789 SYM 0.8874
790 6F0 0.8873
791 6M1 0.8872
792 ZYR 0.8872
793 GLO 0.8871
794 449 0.8871
795 MPV 0.8870
796 HY1 0.8866
797 X6X 0.8866
798 A2F 0.8866
799 K34 0.8866
800 PEA 0.8866
801 FHC 0.8866
802 GLF 0.8865
803 HMU 0.8864
804 4HO 0.8864
805 GRE 0.8863
806 495 0.8863
807 DE5 0.8862
808 APZ 0.8861
809 YOF 0.8860
810 GF4 0.8858
811 GLT 0.8857
812 2AC 0.8857
813 EN1 0.8857
814 FQI 0.8856
815 0FK 0.8855
816 QBM 0.8854
817 5JC 0.8854
818 FDB 0.8854
819 FUL 0.8854
820 HDL 0.8853
821 290 0.8853
822 M2K 0.8853
823 M45 0.8852
824 RBJ 0.8852
825 YH7 0.8849
826 1MC 0.8848
827 LGC 0.8848
828 VK3 0.8848
829 INE 0.8848
830 JND 0.8847
831 RUY 0.8847
832 BNT 0.8846
833 FRU 0.8846
834 1WC 0.8846
835 HSO 0.8845
836 QWN 0.8845
837 2MP 0.8845
838 9KT 0.8845
839 2FQ 0.8844
840 P92 0.8843
841 C2B 0.8843
842 EQT 0.8842
843 APS 0.8842
844 HT4 0.8841
845 XHP 0.8840
846 0CT 0.8840
847 TEP 0.8840
848 5MH 0.8839
849 JG8 0.8839
850 SRO 0.8839
851 RAM 0.8839
852 LEU 0.8838
853 1LN 0.8837
854 A1U 0.8837
855 ICP 0.8837
856 1GP 0.8836
857 8TX 0.8835
858 261 0.8834
859 BTE 0.8834
860 PD2 0.8834
861 BMA 0.8834
862 CFP 0.8833
863 RSF 0.8833
864 YIO 0.8832
865 TTY 0.8831
866 FH2 0.8830
867 CRN 0.8830
868 MWM 0.8830
869 1DW 0.8830
870 LSA 0.8830
871 IT2 0.8830
872 MNM 0.8829
873 2F6 0.8829
874 1WG 0.8827
875 BNF 0.8827
876 5WY 0.8827
877 DGL 0.8827
878 CFF 0.8826
879 PYD 0.8825
880 1U6 0.8825
881 23A 0.8824
882 AJY 0.8824
883 PDC 0.8824
884 42A 0.8823
885 NF3 0.8823
886 HL4 0.8821
887 293 0.8821
888 WOO 0.8820
889 2FT 0.8819
890 HNL 0.8819
891 RB5 0.8818
892 XYL 0.8818
893 SOR 0.8818
894 FDR 0.8818
895 SYA 0.8817
896 C1M 0.8817
897 GAG 0.8817
898 4JM 0.8815
899 XYD 0.8815
900 YTX 0.8814
901 H8N 0.8813
902 948 0.8813
903 LZ2 0.8813
904 MBG 0.8813
905 C2A 0.8812
906 TM7 0.8812
907 1XN 0.8812
908 E7S 0.8812
909 36Y 0.8811
910 535 0.8811
911 1A7 0.8810
912 IWT 0.8810
913 AZF 0.8810
914 FUD 0.8809
915 FDK 0.8809
916 JZ9 0.8809
917 IUR 0.8809
918 AOS 0.8807
919 NSP 0.8807
920 ZZT 0.8807
921 39A 0.8806
922 EV0 0.8806
923 F5B 0.8805
924 PPY 0.8805
925 0BP 0.8803
926 DEE 0.8803
927 QX4 0.8803
928 CXH 0.8802
929 B55 0.8801
930 2CQ 0.8800
931 DQU 0.8800
932 94B 0.8799
933 F9Y 0.8799
934 8HC 0.8799
935 RIB 0.8799
936 O2A 0.8799
937 LRH 0.8799
938 1XA 0.8799
939 4BY 0.8797
940 HZQ 0.8796
941 JBQ 0.8796
942 8NX 0.8796
943 PJW 0.8796
944 XUL 0.8795
945 PGA 0.8794
946 B09 0.8794
947 4AV 0.8793
948 LZM 0.8793
949 43M 0.8793
950 AX3 0.8793
951 B0D 0.8792
952 PH3 0.8791
953 GIO 0.8791
954 LPK 0.8790
955 JA8 0.8789
956 E35 0.8789
957 R9Y 0.8789
958 AM4 0.8788
959 OTW 0.8787
960 7MK 0.8787
961 NK 0.8787
962 RIP 0.8785
963 PXM 0.8784
964 YPN 0.8783
965 Z13 0.8783
966 1KP 0.8783
967 1XM 0.8783
968 4JO 0.8783
969 263 0.8782
970 OXQ 0.8782
971 BNL 0.8782
972 QPR 0.8781
973 DRL 0.8781
974 DFB 0.8780
975 M1Z 0.8780
976 NAG 0.8779
977 3W8 0.8778
978 0FO 0.8778
979 SHG 0.8778
980 QXW 0.8778
981 AHB 0.8777
982 XAZ 0.8777
983 3ZB 0.8777
984 150 0.8775
985 PZM 0.8774
986 6KT 0.8774
987 PMF 0.8773
988 JXN 0.8772
989 091 0.8772
990 OK7 0.8772
991 GBD 0.8771
992 2LP 0.8770
993 2AK 0.8770
994 8H8 0.8770
995 4JE 0.8769
996 PEY 0.8768
997 4RU 0.8767
998 EMZ 0.8766
999 DIU 0.8766
1000 BPY 0.8766
1001 IPZ 0.8764
1002 PEL 0.8764
1003 RXA 0.8763
1004 MO8 0.8763
1005 I4B 0.8762
1006 BCP 0.8760
1007 F12 0.8760
1008 7VP 0.8759
1009 LTL 0.8758
1010 5JL 0.8758
1011 BSX 0.8757
1012 94W 0.8757
1013 QBK 0.8756
1014 JF6 0.8756
1015 60P 0.8755
1016 ITN 0.8754
1017 4MU 0.8754
1018 2TQ 0.8754
1019 3CU 0.8754
1020 MZG 0.8753
1021 7D2 0.8752
1022 NYL 0.8752
1023 GCO 0.8752
1024 TT4 0.8751
1025 7ZE 0.8751
1026 XYS 0.8751
1027 OXZ 0.8750
1028 BOA 0.8750
1029 0CU 0.8750
1030 4JJ 0.8748
1031 SME 0.8747
1032 MZB 0.8747
1033 0MK 0.8746
1034 HA7 0.8745
1035 4PN 0.8744
1036 AS3 0.8744
1037 4CM 0.8744
1038 PSE 0.8743
1039 44W 0.8743
1040 NGO 0.8742
1041 TLD 0.8742
1042 FUC 0.8742
1043 8IG 0.8741
1044 SOL 0.8739
1045 XXP 0.8739
1046 264 0.8738
1047 SD4 0.8736
1048 FA6 0.8736
1049 4JP 0.8736
1050 L14 0.8735
1051 JZ2 0.8735
1052 5AC 0.8735
1053 CFA 0.8734
1054 64K 0.8734
1055 8W9 0.8731
1056 MAN 0.8730
1057 57O 0.8730
1058 ZYX 0.8729
1059 GJP 0.8729
1060 MQB 0.8728
1061 J6W 0.8728
1062 3MG 0.8727
1063 463 0.8726
1064 8NB 0.8726
1065 KJM 0.8725
1066 B53 0.8724
1067 DNC 0.8722
1068 FLA 0.8722
1069 4TU 0.8721
1070 HYP 0.8721
1071 4CL 0.8721
1072 ABN 0.8721
1073 TZE 0.8720
1074 PKU 0.8720
1075 3HG 0.8719
1076 P3K 0.8718
1077 54D 0.8717
1078 2ZQ 0.8717
1079 B60 0.8717
1080 4V2 0.8716
1081 FCA 0.8715
1082 AMC 0.8715
1083 B40 0.8714
1084 CWJ 0.8714
1085 27Y 0.8713
1086 JZ4 0.8712
1087 271 0.8711
1088 RPQ 0.8711
1089 HNQ 0.8711
1090 AES 0.8711
1091 XQG 0.8710
1092 DFU 0.8709
1093 F81 0.8708
1094 KDF 0.8707
1095 MAQ 0.8706
1096 PRF 0.8706
1097 AY4 0.8705
1098 AGK 0.8705
1099 ORN 0.8704
1100 AN3 0.8704
1101 14J 0.8703
1102 UAN 0.8702
1103 MT5 0.8702
1104 A5E 0.8702
1105 IYR 0.8701
1106 KYD 0.8701
1107 45C 0.8700
1108 3DM 0.8700
1109 1HN 0.8699
1110 JKZ 0.8699
1111 SW7 0.8698
1112 O7U 0.8694
1113 MB1 0.8693
1114 DMJ 0.8692
1115 209 0.8690
1116 5NE 0.8689
1117 GV9 0.8689
1118 DIE 0.8688
1119 9KH 0.8687
1120 M3H 0.8686
1121 PH2 0.8686
1122 E0O 0.8686
1123 3R6 0.8685
1124 505 0.8685
1125 7MH 0.8685
1126 6R8 0.8684
1127 KTJ 0.8684
1128 NID 0.8683
1129 GIF 0.8683
1130 GZQ 0.8683
1131 2MN 0.8683
1132 27B 0.8683
1133 6LW 0.8682
1134 2AS 0.8682
1135 BZJ 0.8682
1136 ZB1 0.8681
1137 MVN 0.8681
1138 SXS 0.8680
1139 A7N 0.8679
1140 6XI 0.8679
1141 4PW 0.8679
1142 1L5 0.8678
1143 KMH 0.8677
1144 JZ3 0.8676
1145 N2M 0.8675
1146 PFB 0.8673
1147 LKA 0.8672
1148 XXR 0.8671
1149 2BX 0.8670
1150 5WX 0.8670
1151 F4Z 0.8670
1152 1AL 0.8669
1153 2GS 0.8669
1154 PRA 0.8669
1155 R8S 0.8668
1156 A9P 0.8668
1157 3Z7 0.8668
1158 1Z6 0.8667
1159 F69 0.8666
1160 PSV 0.8666
1161 ARB 0.8666
1162 N1E 0.8665
1163 SDD 0.8665
1164 KDV 0.8665
1165 TZM 0.8664
1166 S76 0.8664
1167 H33 0.8663
1168 4NB 0.8663
1169 9BF 0.8663
1170 KYA 0.8663
1171 8G0 0.8661
1172 JIF 0.8660
1173 F4K 0.8660
1174 9UL 0.8659
1175 HY3 0.8659
1176 GPJ 0.8657
1177 GPF 0.8657
1178 95Z 0.8656
1179 PFL 0.8653
1180 BR9 0.8652
1181 HX4 0.8651
1182 XLS 0.8650
1183 TC7 0.8650
1184 7CT 0.8650
1185 JUG 0.8649
1186 MWJ 0.8647
1187 SNO 0.8647
1188 4ZC 0.8646
1189 5WU 0.8645
1190 PHH 0.8645
1191 L22 0.8645
1192 2CZ 0.8643
1193 30G 0.8643
1194 XDK 0.8643
1195 282 0.8643
1196 2K8 0.8642
1197 2A7 0.8641
1198 SLC 0.8640
1199 XBT 0.8640
1200 PPT 0.8640
1201 D07 0.8639
1202 UY7 0.8639
1203 3RK 0.8638
1204 QMR 0.8637
1205 4BL 0.8637
1206 CLZ 0.8636
1207 680 0.8636
1208 HHR 0.8635
1209 LI6 0.8634
1210 ZEC 0.8631
1211 X1S 0.8630
1212 PAF 0.8629
1213 G1O 0.8628
1214 CIT 0.8627
1215 RNO 0.8627
1216 ESP 0.8627
1217 2V0 0.8625
1218 PRO 0.8625
1219 RM4 0.8624
1220 XQI 0.8623
1221 T6C 0.8623
1222 28N 0.8622
1223 JXZ 0.8621
1224 CCE 0.8621
1225 BHQ 0.8620
1226 ZBT 0.8620
1227 PQ0 0.8615
1228 FCB 0.8615
1229 3V4 0.8614
1230 FPY 0.8613
1231 NCD 0.8613
1232 0R0 0.8612
1233 SYN 0.8612
1234 6VD 0.8611
1235 ZZ3 0.8610
1236 HBX 0.8607
1237 OKG 0.8606
1238 ENL 0.8603
1239 CEE 0.8601
1240 C21 0.8600
1241 GCV 0.8599
1242 Y8I 0.8599
1243 JZ5 0.8598
1244 MET 0.8596
1245 2KA 0.8593
1246 QMS 0.8593
1247 SC2 0.8592
1248 4A5 0.8591
1249 PQK 0.8590
1250 PYF 0.8590
1251 0TR 0.8590
1252 TBS 0.8590
1253 3MA 0.8590
1254 EXO 0.8590
1255 NDG 0.8588
1256 TP5 0.8586
1257 URP 0.8583
1258 TZC 0.8582
1259 K17 0.8580
1260 JF2 0.8579
1261 7B3 0.8579
1262 NBE 0.8579
1263 APY 0.8576
1264 NPA 0.8574
1265 46P 0.8571
1266 JZ1 0.8569
1267 P84 0.8560
1268 GBN 0.8558
1269 AZM 0.8557
1270 DC5 0.8555
1271 36M 0.8553
1272 2PC 0.8550
1273 TRP 0.8547
1274 PLU 0.8545
1275 8XQ 0.8542
1276 6QF 0.8542
1277 35C 0.8537
1278 1MR 0.8535
1279 286 0.8534
1280 X0U 0.8534
1281 FOA 0.8532
1282 DDU 0.8530
1283 0XT 0.8526
1284 PYJ 0.8526
1285 K97 0.8520
1286 NLA 0.8519
1287 49O 0.8518
1288 XIZ 0.8517
1289 PRS 0.8509
1290 H76 0.8505
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4K7O; Ligand: EKZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4k7o.bio5) has 11 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4K7O; Ligand: EKZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4k7o.bio5) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4K7O; Ligand: EKZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4k7o.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 4K7O; Ligand: EKZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4k7o.bio4) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 4K7O; Ligand: EKZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 4k7o.bio4) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 4K7O; Ligand: EKZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 4k7o.bio3) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 4K7O; Ligand: EKZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 4k7o.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
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