Receptor
PDB id Resolution Class Description Source Keywords
4LH6 1.65 Å EC: 6.5.1.2 CRYSTAL STRUCTURE OF A LIGA INHIBITOR ENTEROCOCCUS FAECALIS PROTEIN-INHIBITOR COMPLEX LIGASE-LIGASE INHIBITOR COMPLEX
Ref.: IDENTIFICATION THROUGH STRUCTURE-BASED METHODS OF A BACTERIAL NAD(+)-DEPENDENT DNA LIGASE INHIBITOR THA KNOWN RESISTANCE MUTATIONS. BIOORG.MED.CHEM.LETT. V. 24 360 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
1X7 A:401;
Valid;
none;
ic50 = 77 uM
272.122 C8 H6 Br N3 O S c1c2c...
NA A:405;
A:404;
Part of Protein;
Part of Protein;
none;
none;
submit data
22.99 Na [Na+]
NMN A:402;
Valid;
none;
submit data
335.227 C11 H16 N2 O8 P c1cc(...
ACT A:403;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4LH7 1.9 Å EC: 6.5.1.2 CRYSTAL STRUCTURE OF A LIGA INHIBITOR ENTEROCOCCUS FAECALIS PROTEIN-INHIBITOR COMPLEX LIGASE-LIGASE INHIBITOR COMPLEX
Ref.: IDENTIFICATION THROUGH STRUCTURE-BASED METHODS OF A BACTERIAL NAD(+)-DEPENDENT DNA LIGASE INHIBITOR THA KNOWN RESISTANCE MUTATIONS. BIOORG.MED.CHEM.LETT. V. 24 360 2014
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1TA8 - NMN C11 H16 N2 O8 P c1cc(c[n+]....
2 4LH7 ic50 = 34 uM 1X8 C9 H8 N4 O2 S c1c2c(c(cn....
3 4LH6 ic50 = 77 uM 1X7 C8 H6 Br N3 O S c1c2c(c(cn....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1TA8 - NMN C11 H16 N2 O8 P c1cc(c[n+]....
2 4LH7 ic50 = 34 uM 1X8 C9 H8 N4 O2 S c1c2c(c(cn....
3 4LH6 ic50 = 77 uM 1X7 C8 H6 Br N3 O S c1c2c(c(cn....
4 5FPO - 10L C7 H7 N3 c1cc2cn[nH....
5 5FPR - LGA C4 H5 N3 c1cnc(nc1)....
6 4CC6 ic50 = 0.23 uM L5Y C14 H12 F3 N5 O c1cncc2c1c....
7 4CC5 Kd = 38 uM L5V C6 H4 Cl N5 c1c(nc(cn1....
8 4GLW Kd = 0.8 uM 0XT C8 H10 N6 O Cc1c(nc2c(....
50% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1TA8 - NMN C11 H16 N2 O8 P c1cc(c[n+]....
2 4LH7 ic50 = 34 uM 1X8 C9 H8 N4 O2 S c1c2c(c(cn....
3 4LH6 ic50 = 77 uM 1X7 C8 H6 Br N3 O S c1c2c(c(cn....
4 5FPO - 10L C7 H7 N3 c1cc2cn[nH....
5 5FPR - LGA C4 H5 N3 c1cnc(nc1)....
6 4CC6 ic50 = 0.23 uM L5Y C14 H12 F3 N5 O c1cncc2c1c....
7 4CC5 Kd = 38 uM L5V C6 H4 Cl N5 c1c(nc(cn1....
8 4GLW Kd = 0.8 uM 0XT C8 H10 N6 O Cc1c(nc2c(....
9 3PN1 Ki = 110 nM IVH C14 H21 N5 O4 S CCCCSc1nc(....
10 4UFZ - IWH C15 H16 N2 O2 Cc1ccc(c(c....
11 3UQ8 Kd = 45 uM NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 1X7; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 1X7 1 1
2 1X8 0.6 0.863636
Ligand no: 2; Ligand: NMN; Similar ligands found: 21
No: Ligand ECFP6 Tc MDL keys Tc
1 NMN 1 1
2 NNR 0.693548 0.818182
3 NCN 0.647887 0.892308
4 A7R 0.56383 0.863014
5 NAD IBO 0.524752 0.861111
6 8ID 0.524752 0.807692
7 NAD TDB 0.524752 0.861111
8 NGD 0.514563 0.831169
9 NHD 0.509434 0.875
10 NAD 0.509434 0.875
11 NAJ 0.504762 0.875
12 NDO 0.491071 0.888889
13 NAP 0.486726 0.888889
14 NFD 0.486239 0.828947
15 NBP 0.465517 0.831169
16 DND 0.461538 0.851351
17 A3D 0.421053 0.863014
18 N01 0.417391 0.849315
19 AMP NAD 0.415929 0.849315
20 CH 0.407407 0.849315
21 NA0 0.404959 0.876712
Similar Ligands (3D)
Ligand no: 1; Ligand: 1X7; Similar ligands found: 649
No: Ligand Similarity coefficient
1 8XQ 0.9662
2 HNQ 0.9630
3 4AV 0.9606
4 5WY 0.9473
5 VNL 0.9387
6 C2U 0.9382
7 FOT 0.9382
8 FLV 0.9377
9 2ZQ 0.9373
10 NTZ 0.9373
11 3MG 0.9368
12 7ZE 0.9365
13 226 0.9353
14 FE DB1 0.9340
15 X8D 0.9338
16 Q6T 0.9335
17 AKH 0.9322
18 TWO 0.9317
19 DIU 0.9315
20 DNC 0.9303
21 K3Q 0.9293
22 7NI 0.9289
23 ZZ8 0.9286
24 HJP 0.9283
25 CKU 0.9280
26 IJZ 0.9276
27 DNF 0.9275
28 FBG 0.9273
29 UNC 0.9270
30 QPR 0.9266
31 42C 0.9261
32 8GK 0.9254
33 BK9 0.9252
34 6BL 0.9251
35 2J9 0.9247
36 67X 0.9239
37 5PX 0.9236
38 BDP 0.9228
39 7FF 0.9221
40 9AP 0.9221
41 NGO 0.9215
42 GT0 0.9210
43 XQK 0.9209
44 LDR 0.9208
45 NID 0.9207
46 F12 0.9200
47 4MU 0.9199
48 GCB 0.9199
49 7I2 0.9199
50 NGT 0.9199
51 KFH 0.9197
52 BGC 0.9195
53 RD4 0.9195
54 PXL 0.9190
55 CSN 0.9188
56 KIB 0.9186
57 3IT 0.9185
58 HLD 0.9183
59 4ME 0.9183
60 G3F 0.9181
61 UAN 0.9180
62 SYA 0.9177
63 AIN 0.9175
64 7M6 0.9173
65 O2A 0.9171
66 7WR 0.9165
67 HLZ 0.9160
68 DPZ 0.9158
69 7VS 0.9156
70 JR2 0.9154
71 582 0.9153
72 9UG 0.9153
73 12B 0.9152
74 2D3 0.9150
75 EVA 0.9147
76 DBJ 0.9141
77 GLC 0.9140
78 M1H 0.9139
79 8S0 0.9139
80 M0Q 0.9137
81 GCS 0.9136
82 I6G 0.9136
83 V55 0.9135
84 MHK 0.9129
85 PDC 0.9126
86 MBG 0.9125
87 NVU 0.9120
88 II6 0.9120
89 H33 0.9118
90 M0W 0.9118
91 9MG 0.9118
92 VXX 0.9117
93 M5N 0.9112
94 D07 0.9110
95 F0J 0.9108
96 MT8 0.9107
97 VK3 0.9107
98 INE 0.9106
99 JKZ 0.9105
100 VOH 0.9103
101 LI6 0.9096
102 M1E 0.9095
103 692 0.9094
104 680 0.9086
105 B60 0.9083
106 GAL 0.9082
107 GTZ 0.9081
108 4M4 0.9081
109 EUG 0.9081
110 QMS 0.9080
111 JXW 0.9077
112 AY4 0.9073
113 6VD 0.9071
114 3TJ 0.9071
115 GOX 0.9071
116 GV9 0.9069
117 M5K 0.9069
118 JTH 0.9067
119 495 0.9065
120 0GZ 0.9064
121 3MB 0.9060
122 LGC 0.9057
123 28N 0.9055
124 GCU 0.9054
125 TNF 0.9051
126 5OF 0.9050
127 SRO 0.9045
128 CFF 0.9043
129 FXH 0.9041
130 APZ 0.9038
131 5RO 0.9038
132 AQO 0.9038
133 AJ2 0.9036
134 8VE 0.9036
135 209 0.9035
136 MUA 0.9032
137 Q24 0.9032
138 NQ 0.9027
139 HZQ 0.9027
140 OVM 0.9026
141 TTY 0.9026
142 TEP 0.9026
143 MT0 0.9026
144 PFB 0.9025
145 NCD 0.9025
146 CKX 0.9023
147 SYR 0.9022
148 BPU 0.9021
149 64C 0.9021
150 IOS 0.9019
151 9KT 0.9019
152 8WZ 0.9019
153 CBF 0.9012
154 4AA 0.9010
155 4HM 0.9007
156 OKM 0.9005
157 OTD 0.9005
158 Z5P 0.9004
159 ICO 0.9004
160 SR4 0.9003
161 YSO 0.9003
162 0F9 0.9002
163 X09 0.9001
164 AH8 0.9001
165 GCW 0.8996
166 KBG 0.8995
167 OW4 0.8995
168 LF5 0.8995
169 NTM 0.8994
170 UFO 0.8993
171 30G 0.8993
172 NDM 0.8992
173 M6N 0.8992
174 GOG 0.8991
175 4XY 0.8991
176 TNL 0.8989
177 RXA 0.8988
178 PE0 0.8988
179 4HC 0.8986
180 F31 0.8980
181 UEG 0.8980
182 67Y 0.8979
183 MXX 0.8979
184 EOL 0.8977
185 MEW 0.8977
186 URC 0.8977
187 MAQ 0.8976
188 CKA 0.8975
189 ORO 0.8975
190 K22 0.8973
191 DRL 0.8973
192 M6Z 0.8972
193 2LY 0.8971
194 5WX 0.8971
195 DIE 0.8967
196 GDE 0.8966
197 DK1 0.8965
198 M3Q 0.8961
199 23J 0.8961
200 5VJ 0.8959
201 DOR 0.8959
202 AEZ 0.8958
203 DHK 0.8958
204 5WU 0.8955
205 2AK 0.8951
206 NBV 0.8949
207 6R8 0.8948
208 EJZ 0.8948
209 BNT 0.8945
210 5NE 0.8944
211 XM5 0.8944
212 NBG 0.8941
213 4A5 0.8941
214 KYA 0.8939
215 6DP 0.8939
216 1AL 0.8939
217 1U1 0.8938
218 IPT 0.8938
219 OMD 0.8938
220 H7Y 0.8938
221 AZ8 0.8938
222 NLA 0.8937
223 3C1 0.8937
224 PRZ 0.8935
225 9DG 0.8934
226 ASO 0.8933
227 AW5 0.8932
228 D1X 0.8930
229 ZWZ 0.8929
230 GIM 0.8928
231 C2Y 0.8927
232 4KL 0.8927
233 HTP 0.8927
234 OA3 0.8927
235 HKD 0.8926
236 M2K 0.8926
237 6CS 0.8926
238 MB1 0.8924
239 39U 0.8923
240 XQG 0.8922
241 KGK 0.8922
242 5RN 0.8919
243 6XI 0.8916
244 5RG 0.8916
245 3R6 0.8916
246 GLY LEU 0.8916
247 HHA 0.8916
248 28S 0.8915
249 MO8 0.8913
250 54G 0.8912
251 BMA 0.8911
252 L07 0.8910
253 X0W 0.8908
254 4TU 0.8907
255 34D 0.8904
256 5MK 0.8903
257 HQD 0.8903
258 PEY 0.8901
259 SHG 0.8900
260 XH2 0.8899
261 8WO 0.8898
262 5JQ 0.8898
263 DBH 0.8895
264 DIN 0.8893
265 G5V 0.8892
266 9KH 0.8891
267 4VS 0.8891
268 XAZ 0.8891
269 7B3 0.8890
270 8IG 0.8890
271 3F0 0.8890
272 B55 0.8888
273 B62 0.8887
274 TQU 0.8887
275 EA1 0.8886
276 3HA 0.8885
277 0N7 0.8883
278 C9E 0.8883
279 7VJ 0.8882
280 KT7 0.8881
281 3WA 0.8881
282 K32 0.8880
283 NOJ 0.8878
284 A7W 0.8878
285 8TX 0.8878
286 2JK 0.8877
287 463 0.8876
288 5NS 0.8876
289 PQK 0.8875
290 TOF 0.8875
291 KIA 0.8873
292 8G0 0.8871
293 NFQ 0.8870
294 ESI 0.8869
295 A13 0.8868
296 9TZ 0.8866
297 75K 0.8866
298 512 0.8865
299 PYQ 0.8864
300 QAT 0.8864
301 92P 0.8858
302 H6B 0.8858
303 CLZ 0.8858
304 GTQ 0.8858
305 AZ9 0.8857
306 OTW 0.8857
307 TSS 0.8855
308 JUG 0.8855
309 0GY 0.8853
310 Q88 0.8853
311 LKA 0.8852
312 GTR 0.8852
313 5M0 0.8852
314 3RI 0.8852
315 12M 0.8848
316 GNL 0.8848
317 KFN 0.8847
318 QBK 0.8845
319 G12 0.8845
320 MJ2 0.8845
321 5JL 0.8843
322 SOR 0.8843
323 PD2 0.8843
324 OXC 0.8842
325 7MX 0.8841
326 GUN 0.8841
327 0P6 0.8841
328 XHP 0.8840
329 24W 0.8840
330 H05 0.8839
331 V6F 0.8838
332 DHB 0.8835
333 MRW 0.8835
334 948 0.8833
335 3MA 0.8833
336 ADK 0.8832
337 AQK 0.8831
338 ONR 0.8830
339 FGZ 0.8830
340 G1O 0.8829
341 0LH 0.8827
342 3M0 0.8827
343 CIT 0.8827
344 F2W 0.8827
345 BTY 0.8826
346 JBQ 0.8825
347 MVL 0.8824
348 8VN 0.8823
349 SKM 0.8822
350 P84 0.8821
351 06B 0.8821
352 4NC 0.8820
353 6ME 0.8820
354 44V 0.8816
355 BEA 0.8816
356 GLY PRO 0.8815
357 4XS 0.8814
358 GIO 0.8812
359 9PY 0.8811
360 QSH 0.8810
361 NOY 0.8809
362 IAC 0.8808
363 XX2 0.8807
364 44W 0.8807
365 2EC 0.8807
366 1NP 0.8806
367 KJY 0.8804
368 GTL 0.8804
369 LZ2 0.8804
370 0W8 0.8802
371 NAG 0.8801
372 TXW 0.8801
373 1XM 0.8800
374 QSB 0.8800
375 G2F 0.8800
376 DQU 0.8799
377 XAN 0.8799
378 37T 0.8798
379 2H5 0.8798
380 MVN 0.8798
381 2FQ 0.8797
382 YH7 0.8796
383 1SQ 0.8795
384 IHB 0.8795
385 MAN 0.8794
386 I3A 0.8794
387 BOA 0.8792
388 1LQ 0.8792
389 P9P 0.8792
390 2AL 0.8790
391 PX7 0.8789
392 7HQ 0.8789
393 HA5 0.8789
394 AZA 0.8789
395 39A 0.8788
396 EV0 0.8785
397 ZB1 0.8785
398 SX1 0.8785
399 SNY 0.8785
400 PHH 0.8784
401 IBM 0.8783
402 9TW 0.8782
403 FLC 0.8782
404 CWS 0.8782
405 4XV 0.8782
406 NDG 0.8781
407 4XH 0.8781
408 N7I 0.8780
409 8CM 0.8779
410 4YS 0.8778
411 2SX 0.8778
412 SOE 0.8775
413 IFL 0.8775
414 3DM 0.8775
415 GJS 0.8775
416 J9W 0.8774
417 55D 0.8772
418 ICT 0.8770
419 18N 0.8770
420 M1Q 0.8769
421 MYJ 0.8769
422 B57 0.8769
423 GM7 0.8768
424 JBK 0.8768
425 N8Y 0.8767
426 3HM 0.8767
427 K68 0.8766
428 HH8 0.8765
429 IGA 0.8765
430 TFU 0.8763
431 5Q0 0.8762
432 FHB 0.8762
433 GYE 0.8761
434 L7T 0.8761
435 NNO 0.8760
436 H5B 0.8758
437 4A3 0.8758
438 ZVO 0.8757
439 JPZ 0.8757
440 CHB 0.8756
441 FRU 0.8756
442 JLZ 0.8756
443 K17 0.8756
444 141 0.8754
445 SXS 0.8754
446 6OT 0.8753
447 JND 0.8753
448 2FG 0.8753
449 93K 0.8753
450 ES1 0.8751
451 ISE 0.8749
452 EDM 0.8748
453 E7R 0.8747
454 5IQ 0.8747
455 9FE 0.8747
456 1QP 0.8745
457 MS9 0.8743
458 GZL 0.8741
459 BSP 0.8741
460 RPQ 0.8740
461 GZ8 0.8740
462 KJU 0.8740
463 N5J 0.8739
464 A2F 0.8737
465 PA1 0.8737
466 FA6 0.8736
467 G1P 0.8736
468 6AP 0.8735
469 K37 0.8735
470 GNV 0.8735
471 8HC 0.8735
472 4AN 0.8735
473 5SG 0.8734
474 BCP 0.8733
475 3Z7 0.8733
476 HQY 0.8733
477 INO 0.8731
478 57O 0.8731
479 3FH 0.8730
480 ES0 0.8730
481 Q7A 0.8730
482 3C2 0.8730
483 JTA 0.8729
484 CWM 0.8729
485 82I 0.8728
486 LCN 0.8728
487 0FK 0.8727
488 DBX 0.8726
489 60Q 0.8725
490 GLA 0.8723
491 TBS 0.8723
492 M4E 0.8723
493 MYI 0.8721
494 1U6 0.8719
495 XFE 0.8719
496 8WT 0.8718
497 2HO 0.8714
498 UFV 0.8713
499 FBU 0.8713
500 LJW 0.8713
501 LZM 0.8711
502 774 0.8710
503 KUF 0.8709
504 S76 0.8708
505 42A 0.8707
506 TRA 0.8707
507 3Z8 0.8704
508 QAS 0.8701
509 R8S 0.8696
510 878 0.8696
511 6GU 0.8695
512 1P7 0.8695
513 ADA 0.8694
514 SWA 0.8692
515 NIG 0.8691
516 1XN 0.8691
517 0FO 0.8690
518 PXM 0.8689
519 290 0.8689
520 64E 0.8688
521 YQA 0.8688
522 CTS 0.8687
523 JXN 0.8686
524 YIO 0.8686
525 DX4 0.8684
526 AX3 0.8684
527 DRG 0.8683
528 IV2 0.8681
529 AZG 0.8681
530 DNA 0.8680
531 2D0 0.8678
532 FDR 0.8674
533 Q71 0.8672
534 JU2 0.8672
535 W81 0.8671
536 0W1 0.8670
537 5B1 0.8670
538 4ZC 0.8666
539 UQ 0.8666
540 SJ5 0.8666
541 CIY 0.8663
542 12Q 0.8659
543 X0V 0.8659
544 0CU 0.8657
545 X05 0.8656
546 WOO 0.8656
547 PRF 0.8656
548 0XT 0.8655
549 PHT 0.8652
550 AM1 0.8651
551 IFM 0.8650
552 RM1 0.8650
553 HQT 0.8650
554 EYK 0.8649
555 5QX 0.8648
556 KTW 0.8648
557 KBB 0.8648
558 1LM 0.8646
559 G6D 0.8645
560 3HB 0.8644
561 NQM 0.8643
562 G3E 0.8643
563 5VL 0.8638
564 EXO 0.8637
565 LT3 0.8636
566 X6X 0.8635
567 K5W 0.8635
568 5GU 0.8633
569 3NT 0.8632
570 QM1 0.8631
571 4NO 0.8631
572 1GN 0.8629
573 CFP 0.8626
574 4Z4 0.8625
575 5OB 0.8623
576 TIY 0.8623
577 JBH 0.8623
578 AS3 0.8621
579 E7Z 0.8621
580 3Y7 0.8621
581 FDB 0.8621
582 149 0.8620
583 PQ0 0.8618
584 7B4 0.8617
585 AHR 0.8616
586 AMG 0.8614
587 DEE 0.8613
588 SF9 0.8613
589 JAA 0.8611
590 G4D 0.8611
591 R6T 0.8610
592 SHA 0.8606
593 ZYR 0.8606
594 BZJ 0.8606
595 25W 0.8605
596 J9Q 0.8603
597 8W9 0.8602
598 DMD 0.8601
599 JG8 0.8598
600 54X 0.8596
601 GIV 0.8594
602 3ID 0.8594
603 ROI 0.8593
604 4CS 0.8591
605 O72 0.8591
606 M5H 0.8591
607 XXP 0.8591
608 NMJ 0.8591
609 CCV 0.8590
610 SWD 0.8590
611 I7A 0.8589
612 R9Y 0.8588
613 BZ3 0.8588
614 QX2 0.8585
615 BRT 0.8584
616 BTE 0.8582
617 23A 0.8579
618 32X 0.8578
619 IFP 0.8578
620 E35 0.8576
621 2KA 0.8575
622 KDO 0.8575
623 MQB 0.8574
624 3J8 0.8573
625 GNM 0.8567
626 8NX 0.8565
627 HHT 0.8564
628 4FH 0.8564
629 3AB 0.8563
630 S3P 0.8563
631 WCE 0.8562
632 HH5 0.8560
633 VM1 0.8560
634 ADZ 0.8558
635 RB2 0.8557
636 2A7 0.8556
637 3BZ 0.8555
638 OVV 0.8555
639 B5D 0.8548
640 GAB 0.8545
641 7MH 0.8545
642 SG2 0.8541
643 GDL 0.8541
644 DHQ 0.8540
645 96U 0.8539
646 HQJ 0.8534
647 2CG 0.8531
648 FA3 0.8522
649 PM6 0.8510
Ligand no: 2; Ligand: NMN; Similar ligands found: 109
No: Ligand Similarity coefficient
1 IMP 0.9419
2 AMP 0.9397
3 RVP 0.9374
4 G 0.9355
5 CNU 0.9351
6 5HM 0.9278
7 5GP 0.9252
8 DU 0.9234
9 U5P 0.9211
10 TMP 0.9201
11 5FU 0.9200
12 5BU 0.9196
13 U 0.9194
14 FMP 0.9162
15 5HU 0.9159
16 TKW 0.9155
17 XMP 0.9153
18 UMP 0.9150
19 C 0.9141
20 C2R 0.9140
21 C5P 0.9138
22 SRA 0.9132
23 IMU 0.9114
24 71V 0.9111
25 IRP 0.9110
26 UP6 0.9110
27 UFP 0.9107
28 PFU 0.9106
29 AMZ 0.9103
30 G7M 0.9103
31 NYM 0.9096
32 NIA 0.9094
33 QBT 0.9086
34 DG 0.9085
35 MZP 0.9079
36 FDM 0.9069
37 5IU 0.9061
38 D5M 0.9052
39 9L3 0.9051
40 BRU 0.9049
41 AS 0.9036
42 FNU 0.9035
43 DA 0.9008
44 DUS 0.8994
45 DGP 0.8993
46 PSU 0.8984
47 8OP 0.8974
48 6MA 0.8968
49 E8B 0.8968
50 DCM 0.8961
51 QIU 0.8958
52 H2U 0.8953
53 16B 0.8943
54 CAR 0.8941
55 6MZ 0.8935
56 8OG 0.8916
57 8GM 0.8911
58 BVP 0.8907
59 8BR 0.8900
60 ZAS 0.8897
61 EFX 0.8895
62 A3N 0.8893
63 U4S 0.8887
64 6CG 0.8886
65 T3S 0.8869
66 MLO 0.8864
67 FN5 0.8844
68 N5O 0.8840
69 J7C 0.8828
70 FYK 0.8826
71 6OG 0.8819
72 6RE 0.8810
73 UMC 0.8805
74 ICR 0.8801
75 D4M 0.8796
76 2DT 0.8796
77 DC 0.8795
78 AIR 0.8790
79 Z8B 0.8784
80 DDN 0.8782
81 8EQ 0.8772
82 5CM 0.8762
83 NEC 0.8748
84 BMP 0.8735
85 7D5 0.8726
86 1BJ 0.8724
87 MTA 0.8711
88 DOC 0.8711
89 MTM 0.8697
90 3F5 0.8693
91 EU2 0.8688
92 BMQ 0.8685
93 O7E 0.8674
94 ATM 0.8654
95 U3S 0.8651
96 U1S 0.8644
97 CZV 0.8640
98 K6B 0.8635
99 FGR 0.8633
100 LIT 0.8632
101 NUP 0.8628
102 SU1 0.8614
103 IRN 0.8613
104 U2S 0.8610
105 4ZK 0.8594
106 S5P 0.8568
107 MCF 0.8552
108 ADP 0.8537
109 581 0.8533
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4LH7; Ligand: 1X8; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4lh7.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4LH7; Ligand: NMN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4lh7.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
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