Receptor
PDB id Resolution Class Description Source Keywords
4QNA 1.85 Å EC: 2.7.11.1 MST3 IN COMPLEX WITH 2-(4,6-DIAMINO-1,3,5-TRIAZIN-2-YL)PHENO HOMO SAPIENS PROTEIN KINASE MST3 STK24 STERILE 20-LIKE KINASE ATP-BINNUCLEOTIDE-BINDING PHOSPHOPROTEIN SERINE/THREONINE-TRANSFTRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: DISCOVERY OF DIVERSE SMALL-MOLECULE INHIBITORS OF M STERILE20-LIKE KINASE 3 (MST3). CHEMMEDCHEM V. 11 1137 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
X11 A:401;
Valid;
none;
ic50 = 0.023 uM
203.201 C9 H9 N5 O c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4QMN 2.09 Å EC: 2.7.11.1 MST3 IN COMPLEX WITH BOSUTINIB HOMO SAPIENS PROTEIN KINASE MST3 STK24 STERILE 20-LIKE KINASE ATP-BINNUCLEOTIDE-BINDING PHOSPHOPROTEIN SERINE/THREONINE-TRANSFTRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: DISCOVERY OF DIVERSE SMALL-MOLECULE INHIBITORS OF M STERILE20-LIKE KINASE 3 (MST3). CHEMMEDCHEM V. 11 1137 2016
Members (22)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 133 families.
1 4QMP ic50 = 0.014 uM DKI C15 H13 F2 N7 O2 S2 c1cc(c(c(c....
2 4U8Z - 3FE C17 H15 N5 O c1cc(cc(c1....
3 4QMX ic50 = 11 uM H8H C27 H32 Cl N5 O5 CN1CCN(CC1....
4 4QMT ic50 = 0.01 uM H1N C29 H32 N4 O3 S CCS(=O)(=O....
5 4QMM ic50 = 0.46 uM 35R C19 H23 N7 O2 c1cc2c(cc1....
6 4QMU ic50 = 1.3 uM SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
7 4W8E - 3JB C20 H17 N7 O2 Cc1nc(no1)....
8 4QMZ ic50 = 0.21 uM B49 C22 H27 F N4 O2 CCN(CC)CCN....
9 4QNA ic50 = 0.023 uM X11 C9 H9 N5 O c1ccc(c(c1....
10 4QMO ic50 = 0.019 uM 34L C13 H8 N4 O S c1cc2c(c3c....
11 4QMW ic50 = 0.086 uM KS1 C17 H17 N7 c1c[nH]c2c....
12 3A7H - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
13 4QML - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
14 4QO9 ic50 = 0.16 uM 627 C26 H30 N6 O3 CN1CCN(CC1....
15 4QMQ ic50 = 0.26 uM 34U C24 H27 N5 O2 COCCOc1ccc....
16 4QMY ic50 = 0.004 uM STU C28 H26 N4 O3 C[C@@]12[C....
17 3A7J - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
18 4W8D - 3JA C14 H16 N6 O Cn1cc(cn1)....
19 4QMN ic50 = 0.003 uM DB8 C26 H29 Cl2 N5 O3 CN1CCN(CC1....
20 4QMS ic50 = 7.4 uM 1N1 C22 H26 Cl N7 O2 S Cc1cccc(c1....
21 4QMV ic50 = 0.023 uM 34W C23 H25 F3 N6 O2 CC(=O)NCC(....
22 3A7I - ADE C5 H5 N5 c1[nH]c2c(....
70% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 101 families.
1 4QMP ic50 = 0.014 uM DKI C15 H13 F2 N7 O2 S2 c1cc(c(c(c....
2 4U8Z - 3FE C17 H15 N5 O c1cc(cc(c1....
3 4QMX ic50 = 11 uM H8H C27 H32 Cl N5 O5 CN1CCN(CC1....
4 4QMT ic50 = 0.01 uM H1N C29 H32 N4 O3 S CCS(=O)(=O....
5 4QMM ic50 = 0.46 uM 35R C19 H23 N7 O2 c1cc2c(cc1....
6 4QMU ic50 = 1.3 uM SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
7 4W8E - 3JB C20 H17 N7 O2 Cc1nc(no1)....
8 4QMZ ic50 = 0.21 uM B49 C22 H27 F N4 O2 CCN(CC)CCN....
9 4QNA ic50 = 0.023 uM X11 C9 H9 N5 O c1ccc(c(c1....
10 4QMO ic50 = 0.019 uM 34L C13 H8 N4 O S c1cc2c(c3c....
11 4QMW ic50 = 0.086 uM KS1 C17 H17 N7 c1c[nH]c2c....
12 3A7H - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
13 4QML - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
14 4QO9 ic50 = 0.16 uM 627 C26 H30 N6 O3 CN1CCN(CC1....
15 4QMQ ic50 = 0.26 uM 34U C24 H27 N5 O2 COCCOc1ccc....
16 4QMY ic50 = 0.004 uM STU C28 H26 N4 O3 C[C@@]12[C....
17 3A7J - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
18 4W8D - 3JA C14 H16 N6 O Cn1cc(cn1)....
19 4QMN ic50 = 0.003 uM DB8 C26 H29 Cl2 N5 O3 CN1CCN(CC1....
20 4QMS ic50 = 7.4 uM 1N1 C22 H26 Cl N7 O2 S Cc1cccc(c1....
21 4QMV ic50 = 0.023 uM 34W C23 H25 F3 N6 O2 CC(=O)NCC(....
22 3A7I - ADE C5 H5 N5 c1[nH]c2c(....
23 3GGF - GVD C22 H19 N7 c1ccc2c(c1....
50% Homology Family (663)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3IGO - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 3NCG - BK1 C19 H19 N5 CC(C)n1c2c....
3 3MWU - BK3 C22 H24 N6 c1ccc2c(c1....
4 6NG0 Ki = 10 nM B49 C22 H27 F N4 O2 CCN(CC)CCN....
5 2XF0 ic50 = 30 uM 4UB C15 H11 N5 c1ccc(cc1)....
6 2YM6 ic50 = 0.88 uM YM6 C14 H16 N6 O c1cncc2c1c....
7 6FCK ic50 = 0.031 uM D4Z C20 H22 N4 O c1ccc(cc1)....
8 4QYG ic50 = 0.0041 uM 3DW C22 H21 N5 O2 CN1CCN(CC1....
9 3TKH ic50 = 47 nM 07S C23 H27 N7 O2 S c1cc(cnc1)....
10 2XEZ ic50 = 1.5 uM XEZ C12 H9 N7 c1c[nH]nc1....
11 2HXL ic50 = 12 nM 422 C23 H24 N6 c1cc2c(cc1....
12 5OQ7 Ki = 0.322 uM A0Q C24 H26 N4 O2 CN1CCN(CC1....
13 5F4N ic50 = 2.2 nM 5UY C17 H19 N7 O3 COC(=O)c1c....
14 2E9N ic50 = 6.2 nM 76A C29 H27 N3 O3 c1cc(ccc1c....
15 2YM3 ic50 = 1.2 uM YM3 C14 H19 N5 O3 CCOC(=O)c1....
16 2YDI - YDI C16 H20 N4 O3 S CN(C)CCOc1....
17 5OP5 Ki = 0.216 uM 3FE C17 H15 N5 O c1cc(cc(c1....
18 3NLB ic50 = 35 nM 5BE C21 H28 N6 O Cc1c(c([nH....
19 3JVR Ki = 1.89 uM AGX C16 H13 Cl2 N3 O2 C[C@@H](c1....
20 2WMX ic50 = 0.86 uM ZY6 C17 H19 N5 O c1ccc(cc1)....
21 2C3J Ki = 0.659 uM DBQ C11 H11 N5 O2 c1c[nH]c2c....
22 2YM7 ic50 = 0.13 uM YM7 C15 H18 N8 c1c(ncnc1N....
23 2X8I ic50 = 0.19 uM X8I C17 H13 N3 O2 CC1=CC2=NN....
24 2YDJ ic50 = 0.005 uM YDJ C17 H19 F N4 O2 S c1cc(cc(c1....
25 4QYE ic50 = 1.2 uM 3DL C17 H12 N2 O3 c1cc(cc(c1....
26 5OP7 - A1K C19 H21 Cl N6 O3 CNc1c2c(c[....
27 5OOP - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
28 5OPR Ki = 2.56 uM A3E C21 H26 N6 O CC(C)n1cc(....
29 2BRG ic50 = 6.1 uM DFY C21 H19 N3 O2 CN(CCO)c1c....
30 5OQ5 Ki = 0.02 uM 4K4 C31 H38 N8 O3 CN1CCN(CC1....
31 2CGU ic50 = 13.4 uM 3A3 C17 H13 N O7 c1cc-2c(cc....
32 2WMR ic50 = 52 uM ZYR C10 H10 N2 O S C1CCc2c(c3....
33 3PA5 ic50 = 2 nM C73 C17 H19 Cl N4 O2 S c1cc(ccc1c....
34 2WMV ic50 = 9.2 uM ZYV C10 H14 N6 O c1[nH]c2c(....
35 5OQ8 Ki = 1.41 uM A0Q C24 H26 N4 O2 CN1CCN(CC1....
36 2CGX ic50 = 15.6 uM 3D3 C7 H8 N6 O S c1nc(c2c(n....
37 4QYF - 3DV C17 H13 N3 O3 c1cc(cc(c1....
38 5OPS Ki = 0.863 uM A3Q C14 H9 N3 O c1cc(cc(c1....
39 3JVS Kd = 0.29 uM AGY C22 H22 N4 O4 CC(C)(C)c1....
40 2WMW ic50 = 0.39 uM ZYW C11 H14 Br N5 O c1c2c(c(cn....
41 2BR1 Ki = 7.2 uM PFP C22 H21 N3 O4 COc1ccc(cc....
42 2C3L Ki = 8.58 uM IDZ C14 H10 N4 c1ccc2c(c1....
43 5OP2 Ki = 0.24 uM A0Q C24 H26 N4 O2 CN1CCN(CC1....
44 2X8E ic50 = 0.014 uM X8E C16 H12 N4 O CC1=CC2=NN....
45 2X8D ic50 = 0.8 uM X8D C11 H9 N3 O CC1=CC2=NN....
46 2YEX ic50 = 0.0001 uM YEX C15 H12 N4 O CC1=CC2=NN....
47 2BRM Ki = 1.3 uM DFZ C20 H18 N4 O c1ccc(cc1)....
48 1NVQ Ki = 5.6 nM UCN C28 H26 N4 O4 C[C@@]12[C....
49 5OOR - STU C28 H26 N4 O3 C[C@@]12[C....
50 3PA4 ic50 = 3 nM C72 C19 H19 Cl N4 O S c1cc(ccc1c....
51 4RVK ic50 = 13.5 nM 3XK C19 H13 N5 O CC(=O)Nc1c....
52 2HOG ic50 = 0.3 nM 710 C24 H25 N7 O c1cc2c(cc1....
53 6FC8 ic50 = 0.012 uM D4Q C19 H19 F N4 O S c1cc(cc(c1....
54 5R98 - SQG C10 H7 F3 N2 O2 c1cc(ccc1N....
55 5RA8 - 2O6 C8 H5 F3 N2 O c1cc2c(cc1....
56 5R9J - LXS C15 H16 N2 O4 CCN1C(=O)C....
57 4EH2 - IRG C17 H16 N4 c1ccc(cc1)....
58 3HA8 - 5JZ C36 H38 N8 O5 CCOc1nc(nc....
59 6Y7W Kd = 57.8 uM OFW C26 H35 N5 O6 S C[C@@]1(CN....
60 3HEG Kd = 0.18 uM BAX C21 H16 Cl F3 N4 O3 CNC(=O)c1c....
61 2ZAZ Ki = 0.4 uM GK1 C20 H15 N3 O2 S Cc1ccc(cc1....
62 5R9R - K3D C9 H17 N3 O2 CCNC(=O)N1....
63 3HP5 - I46 C14 H9 F2 N3 c1cc(ccc1c....
64 5ML5 ic50 = 10 nM 1VI C26 H25 F N4 O3 S COc1ccc(c(....
65 5R93 - SOJ C12 H12 N2 c1ccc(cc1)....
66 4DLI Kd = 2.4 uM IRG C17 H16 N4 c1ccc(cc1)....
67 3P78 ic50 = 0.11 uM P78 C24 H27 N3 O4 S2 CC(C)(C)c1....
68 5R9Y - SU7 C15 H18 N2 O c1ccc(cc1)....
69 4EH9 - IRG C17 H16 N4 c1ccc(cc1)....
70 1YWR ic50 = 32 nM LI9 C27 H29 F N6 O C[C@@H](c1....
71 3IW5 Kd = 0.839 uM DF3 C28 H24 F3 N3 O4 S c1ccc2c(c1....
72 5R9C - 7ZC C12 H16 N2 O CN(C)Cc1c[....
73 3HV3 ic50 = 900 nM R49 C30 H31 N7 O Cc1cccc(c1....
74 6HWV ic50 = 115 nM GEW C32 H28 F2 N6 O3 Cn1c(c(nc1....
75 5R8U - SLS C10 H11 N O2 c1cc2c(cc1....
76 4A9Y - AQZ C32 H37 N7 O4 Cc1ccc(cc1....
77 5R9Q - LVD C8 H10 N2 O2 c1ccc(cc1)....
78 3GCU - R48 C29 H30 N8 O Cc1ccc(cc1....
79 1OUY ic50 = 4.3 nM 094 C24 H18 Cl2 F2 N4 O S c1cc(c(c(c....
80 5R9L - SRJ C18 H25 N O2 c1ccc(cc1)....
81 3D7Z Ki = 12 nM GK5 C22 H24 N2 O2 Cc1ccc(cc1....
82 2YIS - YIS C35 H34 Cl N7 O3 S2 CC(C)(C)c1....
83 1OUK ic50 = 0.13 nM 084 C28 H29 F3 N6 C[C@@H](c1....
84 6YCW - OL8 C15 H10 N2 O4 c1cc(cc(c1....
85 3BV2 ic50 = 0.44 nM P38 C33 H32 N8 O3 Cc1ccc(cc1....
86 4R3C - GG5 C14 H10 F N3 c1cc(ccc1c....
87 4L8M ic50 = 0.001 uM F46 C33 H30 F N3 O5 c1ccc(cc1)....
88 4E6A - 0O9 C32 H65 O10 P CCCCCCCCCC....
89 1WBN ic50 = 0.35 uM L09 C20 H22 Cl N5 O2 CC(C)(C)c1....
90 6ZWR ic50 = 21.7 nM OEB C34 H39 N7 O3 c1ccc(cc1)....
91 2QD9 ic50 = 13 nM LGF C27 H24 F2 N6 O5 COc1c(cc2c....
92 3HUC Kd = 1030 nM G97 C20 H16 N6 O C=CC(=O)Nc....
93 3HL7 Ki = 0.023 uM I47 C20 H20 Cl N5 O2 c1cc(ccc1c....
94 4EHV - IRG C17 H16 N4 c1ccc(cc1)....
95 5R95 - SQ4 C10 H8 N2 O2 c1cc(ccc1N....
96 2GTN ic50 = 4 nM LIE C20 H16 F3 N5 O CC(C)n1c2c....
97 3HRB ic50 = 21 nM I39 C19 H14 F2 N2 O2 Cc1ccccc1c....
98 3BX5 ic50 = 3.5 nM 304 C17 H22 N4 O2 S CC[C@@H](C....
99 5R9V - SSY C10 H8 F3 N O2 CC(=O)c1cc....
100 3HVC ic50 = 600 nM GG5 C14 H10 F N3 c1cc(ccc1c....
101 2GFS ic50 = 0.7 uM PQB C19 H18 F N3 O4 c1cc(cc(c1....
102 5N63 - 8OW C21 H17 F N4 c1ccc(cc1)....
103 2NPQ Kd = 3.08 uM BOG C14 H28 O6 CCCCCCCCO[....
104 3IW6 Kd = 3.29 uM PP0 C23 H31 N3 O3 CCn1c(c(c(....
105 3S4Q ic50 = 4 nM NK0 C25 H23 N5 O2 Cc1ccc(cc1....
106 2BAJ Kd = 4 nM 1PP C20 H20 Cl2 N4 O CC(C)(C)c1....
107 3ROC - 29B C14 H10 F N3 c1cc(ccc1c....
108 5RA7 - SW7 C8 H9 N O Cc1ccc(cc1....
109 5R8Z - SN4 C7 H8 N2 O S COc1ccc(cn....
110 5R9D - N9J C8 H9 N O3 c1ccc(cc1)....
111 5R9P - SFY C11 H11 N3 O2 S c1ccnc(c1)....
112 3NWW ic50 = 7 nM 3NW C24 H34 N8 O S CCNC(=O)NC....
113 1W83 ic50 = 0.065 uM L11 C23 H25 Cl F N3 O3 c1cc(cnc1)....
114 3ZSH - 469 C27 H30 Cl F N4 O3 C[C@@H]1C[....
115 3IPH Ki = 0.0000251 mM G11 C21 H23 N3 O2 Cc1ccc(cc1....
116 5MZ3 ic50 = 0.0002 uM 8EN C24 H19 F3 N4 O2 Cc1ccc(cc1....
117 5R9W - STV C10 H13 N O4 S CCS(=O)(=O....
118 3P7B ic50 = 0.018 uM P7B C25 H28 N4 O3 S CC(C)(C)c1....
119 5RA1 - PO6 C8 H9 N O2 c1ccc(cc1)....
120 3GCQ Kd = 342 nM 1BU C29 H30 N8 O Cc1cccc(c1....
121 5RA5 - SVJ C8 H16 N2 CN1[C@@H]2....
122 5R9E - S7S C7 H13 N5 O CCCC(=O)Nc....
123 4F9Y Ki = 184 nM LM3 C21 H18 N4 CN(C)c1cc(....
124 5R92 - SO7 C14 H18 N2 O4 CN(C(=O)[C....
125 2BAL Kd = 490 nM PQA C21 H21 F N4 O2 c1cc(cc(c1....
126 3HUB Kd = 8.2 nM 469 C27 H30 Cl F N4 O3 C[C@@H]1C[....
127 4F9W Ki = 114 nM LM4 C21 H18 N4 CN(C)c1cc(....
128 3P5K ic50 = 0.076 uM P5K C24 H27 N3 O4 S2 CC(C)(C)c1....
129 2I0H ic50 = 9 nM 222 C27 H19 Cl2 F N4 O3 c1ccc2c(c1....
130 5R9F - SQP C13 H11 N O2 c1ccc(c(c1....
131 1ZYJ ic50 = 1.5 uM BI5 C19 H16 N2 O2 c1ccc(cc1)....
132 6Y7X - OFQ C11 H19 N O C1C2CC3CC1....
133 3K3I - JZJ C18 H16 Br N3 c1ccc2c(c1....
134 1WBT ic50 = 0.34 uM WBT C26 H25 F N4 O2 c1cc(cc2c1....
135 1BMK - SB5 C17 H16 F N5 c1cc(ccc1c....
136 3E92 Ki = 10 nM G6A C21 H21 N3 O2 Cc1ccc(cc1....
137 3P7A ic50 = 0.52 uM P7A C23 H27 N3 O3 S2 CC(C)(C)c1....
138 6ANL ic50 = 240 nM T75 C24 H21 N3 O S CCc1nc(c(s....
139 3NNX ic50 = 11 nM EDD C22 H23 Cl2 N5 O2 CC(C)(C)C1....
140 4EH4 - IRG C17 H16 N4 c1ccc(cc1)....
141 1KV1 Kd = 1.16 uM BMU C15 H19 Cl N4 O CC(C)(C)c1....
142 5R9U - JMM C13 H16 N2 O3 c1cc(oc1)C....
143 3KF7 ic50 = 40 nM L9G C22 H18 F2 N4 O Cc1ccc(cc1....
144 4KIN ic50 = 4.8 nM 1M8 C22 H19 Cl N2 O2 S Cc1ccc(cc1....
145 5R9N - JFS C14 H12 N2 O c1ccc2c(c1....
146 4AA4 ic50 = 9 nM QC0 C25 H25 N5 O3 Cc1ccc(cc1....
147 5RA9 - SWD C6 H3 Cl N2 S c1csc2c1nc....
148 5XYY ic50 = 9.221 uM P0F C15 H12 Cl F N4 O c1cc(cc(c1....
149 5R97 - RUY C7 H12 N4 O C1CCN(CC1)....
150 3E93 Ki = 1.4 nM 19B C30 H32 N4 O3 Cc1ccc(cc1....
151 5R9O - 54F C11 H10 N2 O c1ccnc(c1)....
152 4AAC ic50 = 6.7 nM AAV C24 H24 N6 O3 Cc1ccc(cc1....
153 4AA0 ic50 = 35 nM AA0 C30 H33 N7 O3 Cc1ccc(cc1....
154 1OZ1 ic50 = 6.5 nM FPH C18 H12 F N3 O c1cc2c(c(c....
155 5N64 - 8OH C19 H16 N4 S c1ccc(cc1)....
156 3IW8 Kd = 13.4 uM HIZ C19 H18 Cl F N4 O2 S c1ccc(cc1)....
157 3LFN ic50 = 3160 nM A27 C23 H21 N3 O2 CCCC(=O)Nc....
158 3PY1 Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
159 2A4L ic50 = 0.4 uM RRC C19 H26 N6 O CC[C@H](CO....
160 1Y8Y ic50 = 2 uM CT7 C13 H11 Cl N4 O2 S CS(=O)(=O)....
161 6GUH Kd = 26 nM FB8 C18 H21 N5 O2 S Cc1ncc(n1C....
162 1OIR ic50 = 0.032 uM HDY C23 H26 N6 O2 Cc1c(n2ccc....
163 1PXJ - CK2 C9 H10 N4 S Cc1c(sc(n1....
164 2VTO ic50 = 0.14 uM LZ8 C17 H13 F N4 O2 c1ccc(cc1)....
165 2BTR ic50 = 95 nM U73 C13 H15 N3 O S CC(C)C1=CN....
166 6Q4K - HHW C16 H12 Cl N O3 c1cc(cc(c1....
167 2VTA ic50 = 185 uM LZ1 C7 H6 N2 c1ccc2c(c1....
168 3EZR - EZR C26 H27 N7 O CN1CCN(CC1....
169 3ULI ic50 = 0.07 uM 1N3 C21 H25 Br N6 O2 COc1ccc(cc....
170 2DS1 ic50 = 3.4 nM 1CD C22 H21 N5 O3 C[C@@H]1C[....
171 5FP5 - 1Y6 C7 H5 F O2 c1cc(ccc1C....
172 2VTH ic50 = 120 uM LZ2 C10 H9 N O3 S c1cc2c(ccc....
173 1KE5 ic50 = 560 nM LS1 C16 H15 N3 O3 S CNS(=O)(=O....
174 3FZ1 - B98 C13 H15 N3 O2 S COc1ccc2c(....
175 1WCC ic50 = 350 uM CIG C4 H4 Cl N3 c1c(nc(cn1....
176 1PXO Ki = 2 nM CK7 C14 H12 N6 O2 S Cc1c(sc(n1....
177 1H00 ic50 = 38 uM FAP C21 H23 F2 N5 O2 CN(C)C[C@@....
178 2R3R - 6SC C18 H14 Br N5 c1ccc(cc1)....
179 1B39 Kd = 0.12 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
180 6Q4C - HH8 C8 H5 Br N2 c1cc2c(ccn....
181 3PXF Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
182 3TI1 - B49 C22 H27 F N4 O2 CCN(CC)CCN....
183 2R3G ic50 = 800 nM SC9 C18 H14 F N5 c1ccc(c(c1....
184 2C69 ic50 = 26 uM CT8 C17 H14 Br N6 c1cc(cc(c1....
185 2VTM ic50 ~ 1 mM LZM C7 H4 N4 c1cnc2c(cn....
186 4ERW - STU C28 H26 N4 O3 C[C@@]12[C....
187 1E1V Ki = 12 uM CMG C12 H17 N5 O c1[nH]c2c(....
188 2VV9 ic50 = 0.017 uM IM9 C23 H29 N7 O2 Cc1ncc(n1C....
189 5IEV - R0N C18 H23 F3 N4 O3 S C[C@H]([C@....
190 6Q48 - HHQ C5 H4 I N O C1C(=CC=NC....
191 4D1X - ESJ C11 H8 N2 O3 S2 c1cc2c(cc1....
192 5MHQ - 8QT C19 H27 N7 O CC[C@@H]([....
193 2BTS ic50 = 20 nM U32 C12 H15 N3 O2 S2 CC(C)c1cnc....
194 6Q4D - HHT C9 H9 Br O3 COc1cc(ccc....
195 1URW ic50 < 0.003 uM I1P C21 H24 N8 O2 S CN(C)CCCNS....
196 5FP6 - MFZ C11 H7 Cl2 N O c1cc(c2c(c....
197 1CKP - PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
198 1KE6 ic50 = 5.7 nM LS2 C17 H15 N5 O3 S2 CNS(=O)(=O....
199 2C6K ic50 = 0.73 uM DT2 C17 H21 N7 O2 S c1cc(ccc1N....
200 6Q4F - 26D C5 H7 N3 c1cc(nc(c1....
201 2R3Q - 5SC C19 H16 Br N5 O Cc1ccccc1c....
202 1OIT ic50 < 0.003 uM HDT C17 H14 N6 O2 S c1ccn2c(c1....
203 3NS9 ic50 = 0.003 uM NS9 C20 H27 N5 O3 CC(C)c1cnn....
204 6Q4I - HGK C13 H11 N O4 c1cc(ccc1C....
205 1H01 ic50 = 22 uM FAL C21 H23 Cl2 N5 O2 CN(C)C[C@H....
206 2EXM - ZIP C10 H13 N5 CC(=CCNc1c....
207 4BGH ic50 = 4 nM 3I6 C13 H16 Br N5 O3 S C[C@H](CO)....
208 2R3F ic50 = 500 nM SC8 C18 H13 Cl2 N5 c1cc(c(c(c....
209 1GII - 1PU C17 H16 N4 O2 c1ccnc(c1)....
210 6Q4B - HHN C4 H3 Br N2 c1c(cncn1)....
211 2R64 ic50 = 0.03 uM 740 C23 H27 N5 O3 S c1cc(ccc1C....
212 5A14 - LQ5 C24 H26 F3 N7 O2 CN1CCN(CC1....
213 2C6L ic50 = 0.27 uM DT4 C17 H22 N8 O2 S c1cc(ccc1N....
214 2W06 - FRV C18 H20 N6 O2 S Cc1ncc(n1C....
215 4EZ7 - STU C28 H26 N4 O3 C[C@@]12[C....
216 6Q4J - HHB C12 H11 N3 O2 c1cc(cc(c1....
217 5D1J ic50 = 48 nM 56H C17 H24 N4 O2 S2 CC(C)(C)c1....
218 5IEY - 6AE C14 H19 N5 O3 S C[C@H]([C@....
219 2VTT ic50 = 0.044 uM LZD C16 H17 F2 N5 O2 c1cc(c(c(c....
220 2VU3 ic50 = 0.047 uM LZE C16 H17 Cl2 N5 O2 c1cc(c(c(c....
221 2B54 - D05 C20 H15 Cl3 N4 O3 CCc1c2c(n(....
222 1GZ8 - MBP C10 H13 N5 O2 CC(C)C(=O)....
223 3PY0 ic50 = 0.13 uM SU9 C13 H11 N3 O2 COc1ccc2c(....
224 2VTR ic50 = 1.5 uM LZB C10 H10 Cl N5 CC(C)Nc1cc....
225 1E1X Ki = 1.3 uM NW1 C11 H17 N5 O2 C1CCC(CC1)....
226 3UNJ ic50 = 11 uM 0BX C17 H14 N4 O2 c1ccc(cc1)....
227 2A0C - CK9 C19 H26 N6 O2 CC[C@H](CO....
228 3TIY - TIY C11 H8 O5 c1c2c(c(c(....
229 2R3I ic50 = 1000 nM SCF C18 H14 F N5 c1ccc(c(c1....
230 1VYZ ic50 = 290 nM N5B C13 H13 N3 O c1ccc(cc1)....
231 3WBL ic50 = 23 uM PDY C20 H26 N6 O CCOc1ccc(c....
232 4RJ3 ic50 = 93 nM 3QS C22 H28 N6 O COC1CCN(CC....
233 2VTN ic50 = 0.85 uM LZ7 C12 H11 F N4 O2 CC(=O)Nc1c....
234 1AQ1 - STU C28 H26 N4 O3 C[C@@]12[C....
235 2C6M ic50 = 0.35 uM DT5 C17 H20 N6 O3 S c1cc(ccc1N....
236 2R3L ic50 = 100 nM SCW C18 H14 Br N5 c1ccc(cc1)....
237 6Q4A - HGW C4 H3 I N2 c1c(cncn1)....
238 1H08 - BYP BWP n/a n/a
239 1B38 Kd = 0.254 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
240 2B52 ic50 = 8 nM D42 C21 H23 N7 O2 S Cc1c(sc(n1....
241 1PXL - CK4 C16 H13 F3 N4 S Cc1c(sc(n1....
242 3S2P ic50 = 0.068 uM PMU C17 H22 N4 O3 CC(C)c1cc(....
243 2R3O ic50 = 600 nM 2SC C19 H17 N5 O c1ccc(cc1)....
244 3IGG ic50 = 95 nM EFQ C16 H19 N3 O3 COc1ccc(cc....
245 1R78 ic50 = 3 nM FMD C20 H20 F N3 O4 C[C@H]([C@....
246 2FVD Ki = 0.003 uM LIA C18 H21 F2 N5 O4 S COc1ccc(c(....
247 2VTL ic50 = 97 uM LZ5 C10 H9 N3 O c1ccc(cc1)....
248 1KE9 ic50 = 660 nM LS5 C16 H15 N5 O3 S c1ccc2c(c1....
249 6Q3B - PYZ C3 H3 I N2 c1c(cn[nH]....
250 1PYE Ki = 386 nM PM1 C21 H13 F2 N3 O2 c1ccc(cc1)....
251 6Q49 - HGQ C5 H4 Br N O C1=CNC(=O)....
252 4EZ3 - 0S0 C11 H10 N4 O4 S c1cc(ccc1/....
253 1H07 ic50 = 3 uM MFP C24 H27 Br N6 O2 Cc1ccc(c(c....
254 2B53 ic50 = 0.6 uM D23 C19 H19 F3 N4 CC(C)(C)Nc....
255 6GUK Kd = 715 nM FC8 C19 H24 Cl N7 CCn1cnc2c1....
256 2DUV ic50 = 0.087 uM 371 C19 H17 N O7 S Cc1cc2c(c(....
257 4D1Z - WG8 C13 H10 N2 O3 S c1cc2ccc(n....
258 6Q4E Kd = 350 uM HH5 C5 H4 I N5 c1[nH]c2c(....
259 4ACM Ki = 210 nM 7YG C20 H23 N7 O3 S CN(C)CCNS(....
260 2C5Y ic50 = 0.25 uM MTW C19 H15 N7 O2 c1cc(cc(c1....
261 6Q4G Kd = 50 uM HJK C13 H11 N5 O2 c1cc(cc(c1....
262 2R3K ic50 = 100 nM SCQ C18 H14 Br N5 c1ccc(cc1)....
263 2V0D - C53 C9 H7 N3 O S [H]/N=C1/N....
264 2W1H ic50 = 0.052 uM L0F C17 H13 N5 O c1ccc(cc1)....
265 1Y91 ic50 = 0.059 uM CT9 C23 H33 N7 O2 S CC(C)c1cnn....
266 4FII - ARG PRO LYS PRO LEU VAL ASP PRO n/a n/a
267 4NJD ic50 = 0.79 uM NJD C21 H20 N8 O COc1nc(nc(....
268 4JDK - ARG ARG ARG ARG SER TRP TYR n/a n/a
269 5XVG Ki = 0.009 uM 8FX C20 H22 Cl N7 O C[C@@H]1CN....
270 5VED - STU C28 H26 N4 O3 C[C@@]12[C....
271 2X4Z Kd = 2.7 nM 7KC C25 H30 N8 O S Cc1nc2ccsc....
272 5XVA Ki = 0.051 uM 8FU C18 H20 Cl N7 O Cc1cc(n[nH....
273 2CDZ - 23D C19 H24 Cl N7 CCn1cnc2c1....
274 4JDI - ARG ARG ARG ARG SER TRP TYR n/a n/a
275 6WLX - LYS LYS ARG LEU SER VAL GLU n/a n/a
276 2ZV2 - 609 C19 H10 N2 O3 c1ccc2c(c1....
277 4ONA ic50 = 0.002 uM UW1 C19 H23 N5 O2 CCOc1ccc2c....
278 4JBV ic50 = 0.003 uM V68 C26 H32 N6 O CC(C)COc1c....
279 3NYV - DTQ C16 H15 N3 O3 COc1cc2c(c....
280 3T3U Ki = 0.0025 uM BK6 C22 H24 N6 O COc1ccc2cc....
281 3KU2 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
282 4M84 ic50 = 0.049 uM 21E C17 H19 N5 O CC(C)(C)n1....
283 3HX4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
284 3UPX Ki = 0.0075 uM B6A C20 H22 N4 O c1ccc(cc1)....
285 3SXF Ki = 0.0025 uM BK5 C20 H21 N5 O CCOc1ccc2c....
286 3T3V Ki = 0.003 uM BK4 C19 H19 N5 O CC(C)n1c2c....
287 3I7B ic50 = 0.066 uM BK1 C19 H19 N5 CC(C)n1c2c....
288 3V5P Ki = 0.0011 uM C88 C19 H24 N6 O Cc1cc(ccc1....
289 3V51 - I76 C25 H22 Cl N5 O CC(C)n1c2c....
290 3UPZ - B5A C11 H16 N6 c1c2c(ncnc....
291 3I7C ic50 = 0.018 uM BK2 C19 H19 N5 CC(C)(C)n1....
292 3V5T - UW9 C24 H30 N6 O CCOc1ccc2c....
293 3N51 - BK3 C22 H24 N6 c1ccc2c(c1....
294 6HME - FXB C21 H21 N O3 CC(C)n1c2c....
295 6HOP - FER C10 H10 O4 COc1cc(ccc....
296 5OTO - AQW C24 H23 Cl2 N3 CCc1ccccc1....
297 3AT4 Kd = 2.26 nM CCK C20 H20 N6 O2 CC(C)Nc1cc....
298 3OWJ Ki = 0.86 uM 1EL C17 H14 N2 O2 Cc1c2c(c(c....
299 6RFF ic50 = 0.37 uM K1B C12 H6 Br N5 O4 S c1cc(c(cc1....
300 6EII - B5W C22 H23 Cl N c1ccc(cc1)....
301 5CU0 - 54R C18 H21 Cl N2 O CC(=O)NCCC....
302 5H8E Kd = 6.33 pM 5Y3 C21 H25 N9 O CC(=O)Nc1c....
303 5OWH - B0K C10 H9 Br4 N3 c1nc2c(n1C....
304 6L1Z - E3U C16 H12 O6 c1cc(c(c2c....
305 3WAR - NIO C6 H5 N O2 c1cc(cnc1)....
306 5MOE Kd = 520 uM OQC C11 H10 Cl N O c1cc(c(cc1....
307 5OUE - AVZ C18 H19 Cl N3 c1ccc(cc1)....
308 5MOD Kd = 300 uM 86L C10 H14 Cl N O CC(C)Oc1cc....
309 6RB1 ic50 = 1.37 uM JWQ C14 H9 F3 N4 O3 S COc1cc(ccc....
310 6TEI - N4N C15 H11 N3 O2 S c1ccnc(c1)....
311 5OWL - B0K C10 H9 Br4 N3 c1nc2c(n1C....
312 6HBN - FXB C21 H21 N O3 CC(C)n1c2c....
313 5CU3 Kd = 0.32 uM 54S C26 H26 Cl N3 O4 c1ccc(cc1)....
314 5OTR - AU8 C13 H12 Cl2 N c1ccc(cc1)....
315 4KWP Ki = 0.04 uM EXX C12 H10 Br4 N2 O3 c1nc2c(n1[....
316 5OSL - A9K C13 H12 Cl N O c1ccc(c(c1....
317 5N9N Ki = 0.41 nM KC5 C20 H15 Cl2 N O4 COc1ccc(cc....
318 5CSP Kd = 58 uM 54G C8 H8 O3 Cc1ccc(c(c....
319 5CTP - 54R C18 H21 Cl N2 O CC(=O)NCCC....
320 5MOW - BR9 C5 H6 Br N3 c1c(cnc(c1....
321 4UB7 Ki = 2.5 nM 3G5 C16 H8 Br2 O5 c1cc(ccc1C....
322 5MMF - JMB C16 H19 Cl N CCC[NH2+]C....
323 5OTH - AQ8 C25 H26 Cl N3 O CCc1ccccc1....
324 1PJK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
325 6YPK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
326 3NSZ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
327 5OTI - AOK C25 H26 Cl N3 CCc1ccccc1....
328 3AXW - TID C9 H7 N3 O2 S c1cc(ccc1c....
329 5MO6 - KXZ C19 H21 Cl N2 O3 c1ccc(cc1)....
330 2PVR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
331 3C13 - EMO C15 H10 O5 Cc1cc2c(c(....
332 5CS6 Kd = 630 uM K82 C10 H14 Cl N O CCCOc1ccc(....
333 6YPH - N5Q C20 H14 N2 O3 S c1ccc2cc(c....
334 3PE2 Ki = 0.175 nM E1B C20 H12 N4 O2 C#Cc1cccc(....
335 5CT0 - 54P C16 H18 Cl N O c1ccc(cc1)....
336 6RCM ic50 = 0.36 uM K0N C17 H18 N4 O3 S CC(C)(C)c1....
337 5CU6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
338 5M4C - 7EY C16 H14 N2 O2 S2 Cc1ccc(cc1....
339 6SPX ic50 = 44 uM DAS ASP ASP ASP ASP ASP LYS 9AB n/a n/a
340 5MO7 - YRA C16 H17 Cl N2 O c1ccc(cc1)....
341 5N9L Ki = 15 nM 8QH C20 H15 Cl2 N O3 Cc1ccc(cc1....
342 5OT5 - AWK C25 H26 Cl N3 CCc1ccccc1....
343 3OWK ic50 = 1.5 uM 18E C16 H11 Cl N2 O Cc1cnc(c2c....
344 5MMR - H83 C17 H21 Cl N2 c1ccc(cc1)....
345 5MPJ - J2P C15 H17 Cl N CC[NH2+]Cc....
346 5OQU - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
347 6GIH - EZN C15 H13 Cl N2 c1cc(c2cc[....
348 6RFE ic50 = 0.28 uM K0Z C13 H9 Br N4 O3 S COc1cc(ccc....
349 6YPG - N5Q C20 H14 N2 O3 S c1ccc2cc(c....
350 5CSV - GAB C7 H7 N O2 c1cc(cc(c1....
351 5MOT - HBD C7 H7 N O2 c1cc(ccc1C....
352 3R0T ic50 = 0.91 nM FU9 C22 H16 F3 N5 O2 c1cc(cc(c1....
353 3PE1 Ki = 0.223 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
354 3JUH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
355 5CLP - 42J C8 H9 Cl2 N c1cc(c(cc1....
356 5ORH Kd = 41 uM A4N C14 H14 Cl N Cc1ccccc1c....
357 3H30 Ki = 29.2 uM RFZ C12 H12 Cl2 N2 O4 c1c2c(cc(c....
358 2ZJW Ki = 0.02 uM REF C14 H6 O8 c1c2c-3c(c....
359 6HOU - V55 C8 H8 O3 COc1cc(ccc....
360 7A4C ic50 = 3.82 uM QWW C5 H Br3 N4 c12c(c(c(n....
361 6YPN - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
362 5OSZ - AHK C24 H25 Cl N3 CCc1ccccc1....
363 4GRB ic50 = 17 nM 0XG C19 H18 N4 O4 S CN(C)C(=O)....
364 5OT6 - AJK C19 H20 Cl N2 c1ccc(cc1)....
365 6EHK - AUW C24 H23 Cl2 N3 CCc1ccccc1....
366 6L24 - E3U C16 H12 O6 c1cc(c(c2c....
367 3MB7 ic50 = 200 nM 14I C16 H8 O6 c1cc2c(cc(....
368 5OS8 - J27 C14 H14 Cl F N Cc1cc(ccc1....
369 5OTY - AUW C24 H23 Cl2 N3 CCc1ccccc1....
370 5OTD - AOW C24 H24 Cl N4 O2 CCc1ccccc1....
371 6GMD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
372 5CVF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
373 6HNY - GHT C19 H19 N O4 CN1CCc2cc(....
374 5CX9 - 551 C20 H23 Cl N2 O3 COC(=O)CC(....
375 5OUL - AWE C13 H11 Cl F N c1cc(cc(c1....
376 4XP0 - 42A C8 H5 N3 c1cc2c(c[n....
377 4QP2 Kd = 940 uM 36R C7 H5 Cl N2 O c1cc2c(cc1....
378 5NHF ic50 < 0.00032 uM 8X5 C23 H25 N5 O2 c1ccc(cc1)....
379 5BUJ ic50 = 0.005 uM 4VB C16 H15 N5 O c1cnccc1c2....
380 6G9J ic50 = 4.1 nM ERK C27 H28 Cl N5 O3 C[C@H](c1c....
381 5BUI ic50 = 0.089 uM 4V9 C17 H15 F N4 c1ccnc(c1)....
382 4QP7 ic50 = 5.9 uM 363 C9 H7 N5 c1c[nH]c2c....
383 3ERK ic50 = 18 uM SB4 C18 H19 F N6 c1cc(ccc1c....
384 6GDQ - EVK C21 H22 Cl2 N4 O2 CC(C)Nc1cc....
385 5V60 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
386 6QA1 - HVK C5 H6 N2 c1ccnc(c1)....
387 1TVO Ki = 0.14 uM FRZ C18 H13 N7 c1ccc(cc1)....
388 6G9A ic50 = 21 nM ESQ C23 H28 Cl N5 O3 c1cc2c(cc1....
389 5BVD ic50 = 0.16 nM 4VF C24 H26 Cl N5 O3 c1cc(cc(c1....
390 4ZZN ic50 = 0.26 uM CQ8 C18 H21 Cl N4 O2 CNC(=O)c1c....
391 3SA0 - NRA C13 H8 O6 c1c(cc2c(c....
392 4ERK ic50 = 27 uM OLO C15 H18 N6 O Cn1cnc2c1n....
393 6GJD ic50 = 0.022 uM F0E C46 H55 N11 O5 c1cnc(nc1)....
394 5U6I - 81Y C19 H22 N4 O2 CC(C)Oc1cc....
395 5NHV ic50 = 0.0028 uM 8QB C16 H19 N5 O2 c1cnc(nc1c....
396 6QAL - HV2 C3 H6 O3 S C1C(CS1(=O....
397 3I5Z Ki = 2 nM Z48 C24 H23 N5 O2 Cc1cnc(nc1....
398 6QA4 - HRZ C5 H5 N O C1=CC(=O)N....
399 4N0S - DHC C9 H8 O4 c1cc(c(cc1....
400 5NHP ic50 = 0.023 uM 8XK C19 H23 N7 O2 Cn1c(ccn1)....
401 3I60 Ki < 2 nM E86 C24 H22 Cl N5 O2 Cc1cnc(nc1....
402 4XP2 - TT4 C8 H9 N5 c1ccc(cc1)....
403 1PME Ki = 0.76 nM SB2 C21 H16 F N3 O S C[S@](=O)c....
404 6Q7T - HOW C3 H4 N2 O c1conc1N
405 5NHL ic50 < 0.0003 uM 8XB C20 H25 N7 O2 Cc1cnc(nc1....
406 5HD4 - 38Z C33 H33 N9 O2 c1cnc(nc1)....
407 6G97 ic50 = 4.2 nM EQZ C20 H23 Cl N4 O3 COCCN1Cc2c....
408 6G92 ic50 = 76000 nM ERZ C10 H13 N5 Cc1cnc(nc1....
409 5K4I ic50 = 3.1 nM 6QB C21 H18 Cl F N6 O2 Cn1c(ccn1)....
410 3SHE - I85 C24 H22 F3 N5 O2 c1cc(cc(c1....
411 1JNK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
412 5IZJ - 6J9 C10 H13 N5 c1c[nH]c2c....
413 3AG9 Ki = 9 nM A02 C40 H70 N18 O9 [H]/N=C(N)....
414 5IZF Kd = 0.18 nM 6J9 AZ1 DAR ACA DAR NH2 n/a n/a
415 6YPS - P72 C7 H8 N2 O [H]/N=C(c1....
416 6Z44 - IPH C6 H6 O c1ccc(cc1)....
417 6SPU - GAB C7 H7 N O2 c1cc(cc(c1....
418 3DA6 - BZ9 C28 H23 N7 O Cc1cc(c2cc....
419 2R9S ic50 = 0.15 uM 255 C24 H24 N4 O2 S CC(C)(C)NS....
420 4Y5H ic50 = 15 nM 519 C20 H30 N6 O2 CC(C)NC(=O....
421 4X21 Kd = 36 nM 3WH C20 H23 I N6 O CCNC(=O)N1....
422 3RTP ic50 = 7 nM 34I C18 H14 N6 O2 S c1ccc2c(c1....
423 3PZE - CFK C12 H11 N3 O2 S c1ccc(cc1)....
424 4Z9L ic50 = 1.6 nM 880 C27 H34 Cl2 N6 CCCn1c(c(n....
425 4WHZ ic50 < 1 nM 3NL C24 H23 Cl N8 O2 c1ccc(c(c1....
426 4W4Y ic50 = 3034 nM 3HQ C24 H22 N6 O2 Cc1ccc(cc1....
427 4W4W ic50 = 6630 nM 3HJ C23 H20 N6 O2 Cc1cc(ccn1....
428 3G90 Ki = 0.44 uM J72 C17 H12 F2 N2 O4 c1cc2c(cc1....
429 1PMV ic50 = 150 nM 537 C14 H8 N2 O c1ccc2c(c1....
430 2VZ6 - FEF C20 H19 N3 O4 c1ccc2c(c1....
431 2Z7R ic50 ~ 0.4 nM STU C28 H26 N4 O3 C[C@@]12[C....
432 4J8M ic50 = 48 nM CJ5 C26 H25 F3 N8 O c1cc(cc(c1....
433 5ORO - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
434 6HJJ ic50 = 1.7 uM G7T C26 H24 F4 N6 O2 Cc1cc(ccc1....
435 5ORS - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
436 5ORL - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
437 5DR9 - 5E2 C16 H9 Br Cl N O2 c1cc(cc(c1....
438 4DEA ic50 = 256 nM NHI C18 H14 N4 O4 c1cc(ccc1C....
439 5DN3 Kd = 3.77 uM 5DN C16 H9 Br F N O2 c1cc(cc(c1....
440 6C2T - EGJ C27 H26 Cl F N4 O2 S C[C@H]1C[C....
441 5ORP - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
442 4DEE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
443 5OSE Kd = 681 uM A98 C6 H9 N3 O2 S2 CCSc1nnc(s....
444 6R4B - JSN C14 H15 F2 N3 O2 CC1=NC(=O)....
445 5DNR - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
446 6VPJ - GLC GLC n/a n/a
447 6VPL - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
448 3UOD Kd = 49 nM 0C3 C18 H13 F3 N4 O2 c1ccc(c(c1....
449 3EFW - AK8 C25 H21 F3 N6 O2 Cc1cc(ccc1....
450 5DT0 - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
451 3UO4 Kd = 299 nM 0C0 C23 H18 N4 O2 c1ccc(cc1)....
452 3UP2 Kd = 40 nM 0C8 C18 H13 F3 N4 O3 c1ccc(c(c1....
453 5ORX ic50 = 308 uM A6H C11 H8 Cl2 N2 O c1cc(c(c(c....
454 6VPI - MLA C3 H4 O4 C(C(=O)O)C....
455 5ORN - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
456 5OS5 Kd = 410 uM A8K C12 H10 O2 S c1cc(ccc1O....
457 5DR2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
458 3DJ5 - AK5 C21 H20 Br N5 O3 S COc1ccc(cc....
459 6R4D - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
460 3UOL ic50 = 3.1 nM 0C7 C17 H13 Cl N8 c1ccc(c(c1....
461 3D14 ic50 = 22 nM AK1 C19 H15 F3 N6 O S2 c1cc(cc(c1....
462 5OSD - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
463 5OS2 Kd = 1821 uM A7K C13 H21 N2 O c1ccc(c(c1....
464 4BN1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
465 2NP8 ic50 = 42 nM CC3 C21 H18 F3 N5 O c1cc(cc(c1....
466 5ORR Kd = 170 uM A5Q C9 H6 F3 N3 S c1cc(ccc1c....
467 4JBQ - VX6 C23 H28 N8 O S Cc1cc([nH]....
468 5OS3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
469 5DRD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
470 5DPV - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
471 5ORZ Kd = 432 uM A6W C10 H9 N O2 S2 COC(=O)c1c....
472 4UYN ic50 = 4 nM Y3M C25 H22 N4 O4 S CCOC(=O)c1....
473 5DT3 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
474 2WTV Ki = 1.8 nM ZZL C25 H15 Cl F2 N4 O2 c1cc(c(c(c....
475 6HJK ic50 = 25 nM G7W C25 H20 F4 N6 O2 CC(C)n1c2c....
476 3O50 - LJE C24 H17 F3 N4 O2 Cc1cc(ccc1....
477 2J4Z ic50 = 65 nM 626 C23 H24 N6 O2 S CN1CCN(CC1....
478 3LAU ic50 = 0.044 uM OFI C17 H17 N3 O2 CCCC(=O)Nc....
479 3DAJ ic50 = 2.9 uM FXG C22 H29 N7 O2 CCCCNC(=O)....
480 4JBO ic50 = 24 nM WPH C31 H32 N6 O3 CN(C)CCOc1....
481 5ORW Kd = 796 uM A6E C13 H16 F N O2 S c1cc(ccc1O....
482 2C6D - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
483 5OS0 Kd = 2792 uM A6Z C12 H15 Cl N3 c1cc(cc(c1....
484 3K5U ic50 = 309 nM PFQ C20 H17 N3 O2 c1ccc(cc1)....
485 3GC9 - B45 C28 H27 Cl3 F N3 O CC(C)N1CCC....
486 4KS7 - 7KC C25 H30 N8 O S Cc1nc2ccsc....
487 4KS8 - B49 C22 H27 F N4 O2 CCN(CC)CCN....
488 6TE2 - N4N C15 H11 N3 O2 S c1ccnc(c1)....
489 6HMB - 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
490 7A22 ic50 = 1.98 uM QWW C5 H Br3 N4 c12c(c(c(n....
491 3OFM - 4B0 C9 H7 Br4 N3 O C(Cn1c2c(c....
492 6HMC - FXB C21 H21 N O3 CC(C)n1c2c....
493 5YF9 - NIO C6 H5 N O2 c1cc(cnc1)....
494 6TGU - N92 C16 H11 Cl N2 O3 S c1cc(ccc1c....
495 4DGN ic50 = 0.35 uM LU2 C15 H10 O6 c1cc(c(cc1....
496 1M2Q - MNX C13 H7 N O6 c1cc(c2c(c....
497 2OXY - K17 C7 H2 Br4 N2 c1[nH]c2c(....
498 1M2R - MNY C14 H10 N2 O4 c1cc(c2c(c....
499 3KXN - K8X C7 H2 I4 N2 c1[nH]c2c(....
500 6QS5 ic50 = 0.57 uM JGB C10 H8 N2 O3 c1cc(c(cc1....
501 1ZOE Ki = 0.04 uM K25 C9 H7 Br4 N3 CN(C)c1[nH....
502 2PVL Ki = 0.024 uM P55 C18 H20 N8 CCN1CCN(CC....
503 1LP4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
504 2PVN Ki = 0.00035 uM P63 C20 H16 N8 O CC(=O)Nc1c....
505 3KXG - K6X C7 H Br5 N2 c12c(c(c(c....
506 3BE9 Ki = 24 nM P04 C19 H21 N7 O c1cc2cc(c1....
507 2OXX - K22 C7 H2 Br4 N2 S c12c(c(c(c....
508 3KXM - K74 C11 H9 Br4 N3 O S CNC(=O)CSc....
509 1LR4 - BEN C7 H8 N2 [H]/N=C(c1....
510 1OM1 Ki = 0.17 uM IQA C17 H12 N2 O3 c1ccc2c(c1....
511 1ZOH Ki = 0.1 uM K44 C10 H7 Br4 N3 C[N@@]1CCn....
512 2PVK Ki = 0.008 uM P45 C19 H14 Cl N7 c1ccc(cc1)....
513 1DAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
514 5BYZ ic50 = 0.042 uM 4WE C25 H32 F N7 O Cc1ncc(n1C....
515 6HKN ic50 = 0.051 uM G9E C22 H21 F3 N4 O3 COc1ccc2c(....
516 4ZSJ ic50 = 2.3 uM 4R0 C13 H17 Cl N6 O Cc1cc(ccc1....
517 4ZSG - 4QX C12 H15 Cl N6 O CC(C)NC(=O....
518 6HKM ic50 = 270 nM G92 C23 H22 F3 N3 O4 COc1cc2c(c....
519 3EH9 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
520 1IG1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
521 5AUW ic50 = 8.9 uM QUE C15 H10 O7 c1cc(c(cc1....
522 5AV2 - KMP C15 H10 O6 c1cc(ccc1C....
523 5AUU ic50 = 21 uM LU2 C15 H10 O6 c1cc(c(cc1....
524 3EHA - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
525 5AV3 - KMP C15 H10 O6 c1cc(ccc1C....
526 5AUT Kd = 6.7 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
527 5AV0 ic50 = 280 uM 47X C15 H10 O5 c1cc(c(cc1....
528 1JKK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
529 3F5U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
530 5AV4 - GEN C15 H10 O5 c1cc(ccc1C....
531 5AUX ic50 = 10 uM KMP C15 H10 O6 c1cc(ccc1C....
532 5AUV ic50 = 31 uM AGI C15 H10 O5 c1cc(ccc1C....
533 2XK6 - EQH C18 H21 N3 O2 S c1csc(c1C2....
534 2W5A - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
535 5M55 ic50 = 0.24 uM 7GG C17 H20 N6 CCN(CC)/C=....
536 6SK9 ic50 = 1.42 uM F9N C23 H33 N7 O3 S CN(C)CCCNS....
537 2XNM ic50 = 0.16 uM WGZ C27 H27 F3 N4 O3 S C[C@H](c1c....
538 2XKF ic50 = 0.87 uM BX1 C19 H24 N4 O5 COc1cc(cc(....
539 2JAV ic50 ~ 8 uM 5Z5 C17 H16 Cl N3 O2 Cc1c([nH]c....
540 5M53 ic50 = 0.62 uM 7GJ C21 H26 N6 O2 CN(C)C(=O)....
541 2XK8 ic50 = 2.4 uM 5R1 C21 H21 N3 O6 COc1cc(ccc....
542 2WQO - VGK C21 H20 N2 O5 COc1cc(cc(....
543 2XKE ic50 = 4.2 uM WI2 C17 H20 N4 O3 COc1cccc(c....
544 2XNN - 430 C21 H16 F3 N3 O2 S C[C@H](c1c....
545 2XK7 ic50 = 1.5 uM 30E C21 H28 N4 O5 CC[C@H]1C[....
546 1Z5M ic50 = 30 nM LI8 C23 H31 Br N8 O3 CC(C)(C(=O....
547 5HKM ic50 = 0.013 uM 61Y C16 H15 N7 CCc1cc(nc(....
548 3QD0 ic50 = 3.16 nM 3Q4 C24 H26 N8 O C[C@@H]1CC....
549 3ORZ - BI4 C27 H26 N4 O2 C[N@]1CCC[....
550 5LVN Kd = 20 uM ADN C10 H13 N5 O4 c1nc(c2c(n....
551 2XCH ic50 = 374 nM CKG C22 H25 N7 O c1c2c(nc(n....
552 4AW0 - MJF C18 H15 Cl O5 c1ccc(cc1)....
553 3OTU - BI4 C27 H26 N4 O2 C[N@]1CCC[....
554 3QCX ic50 = 63 nM 3Q2 C16 H19 N7 O C[C@@H]1CO....
555 1UU3 ic50 = 0.75 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
556 5LVL Kd = 1.25 uM 537 C14 H8 N2 O c1ccc2c(c1....
557 3QC4 ic50 = 0.002 uM MP7 C28 H22 F2 N4 O4 c1ccc(cc1)....
558 3QCY ic50 = 20 nM 3Q3 C22 H22 N8 O2 c1ccc(cc1)....
559 1UU8 ic50 = 9 uM BI1 C25 H24 N4 O2 CN(C)CCCn1....
560 4CT1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
561 4A07 - AZ7 C17 H13 Cl3 N2 O2 c1cc(ccc1[....
562 2X39 ic50 = 2.2 nM X39 C19 H21 Cl N6 O c1cc(ccc1C....
563 3E87 - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
564 4QNA ic50 = 0.023 uM X11 C9 H9 N5 O c1ccc(c(c1....
565 4QMO ic50 = 0.019 uM 34L C13 H8 N4 O S c1cc2c(c3c....
566 4QMW ic50 = 0.086 uM KS1 C17 H17 N7 c1c[nH]c2c....
567 3A7H - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
568 4QML - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
569 4QO9 ic50 = 0.16 uM 627 C26 H30 N6 O3 CN1CCN(CC1....
570 4QMQ ic50 = 0.26 uM 34U C24 H27 N5 O2 COCCOc1ccc....
571 4QMY ic50 = 0.004 uM STU C28 H26 N4 O3 C[C@@]12[C....
572 3A7J - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
573 4W8D - 3JA C14 H16 N6 O Cn1cc(cn1)....
574 4QMN ic50 = 0.003 uM DB8 C26 H29 Cl2 N5 O3 CN1CCN(CC1....
575 4QMS ic50 = 7.4 uM 1N1 C22 H26 Cl N7 O2 S Cc1cccc(c1....
576 4QMV ic50 = 0.023 uM 34W C23 H25 F3 N6 O2 CC(=O)NCC(....
577 3A7I - ADE C5 H5 N5 c1[nH]c2c(....
578 6ISJ - 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
579 4EL9 - AFE C21 H20 O10 C[C@H]1[C@....
580 5D9L ic50 = 0.024 uM 583 C15 H12 N2 O2 c1cc(ccc1c....
581 6YG2 - 8E8 C25 H26 N6 O2 CCC(=O)N1C....
582 2XK9 ic50 = 0.03 nM XK9 C18 H17 N7 O4 C/C(=NNC(=....
583 2YCS ic50 = 1.36 nM NXP C18 H18 N6 O C/C(=NNC(=....
584 2WTI ic50 = 0.092 uM WTI C18 H15 N3 O3 S c1cc(ccc1c....
585 2YIR ic50 = 0.17 nM YIR C20 H19 N7 O3 [H]/N=C(N)....
586 2XBJ ic50 = 0.003 uM XBJ C23 H27 F N4 O4 CC(C)([C@@....
587 2XM9 ic50 = 0.009 uM LWH C21 H20 N6 O c1ccc2c(c1....
588 2YIQ ic50 = 12.67 nM YIQ C20 H19 N7 O C/C(=NNC(=....
589 2CN5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
590 3HZT - J60 C22 H27 Cl N4 O2 CCN(CC)CCN....
591 4FG8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
592 5K00 ic50 = 7 nM 6PV C32 H34 N6 O4 COc1cccc(c....
593 5MAG - 7KC C25 H30 N8 O S Cc1nc2ccsc....
594 5IHC ic50 = 0.013 uM 6BB C20 H21 F N4 O c1ccc(c(c1....
595 2F57 - 23D C19 H24 Cl N7 CCn1cnc2c1....
596 5L2S - 6ZV C27 H32 F2 N8 CCN1CCN(CC....
597 4AUA ic50 = 7.2 uM 4AU C12 H9 N3 O c1ccc2c(c1....
598 6YLC - OXW C20 H19 F N10 CN1CCC(CC1....
599 6BUU - GLY ARG PRO ARG THR THR ZXW PHE ALA GLU n/a n/a
600 3QKM ic50 = 0.038 uM SM9 C31 H43 N5 O4 S CCOCCN(C[C....
601 3CQU ic50 = 151 nM CQU C15 H13 N7 Cc1[nH]c(n....
602 2WEI ic50 = 3.4 nM VGG C17 H21 N5 Cc1cccc(c1....
603 4EYJ - N61 C20 H23 N5 O2 CC(C)(C)c1....
604 3C0G - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
605 3MFR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
606 4OTI ic50 = 43 nM MI1 C16 H20 N6 O C[C@@H]1CC....
607 6QF4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
608 6SPW ic50 = 4.5 uM DAS ASP ASP ASP ASP ASP LYS A0Z n/a n/a
609 5ONI - 9YE C23 H25 N O3 CC(C)n1c2c....
610 3WF7 ic50 = 206 nM FS9 C18 H17 F3 N6 O c1cc(cc(c1....
611 4L3J - 5FI C19 H21 F3 N6 CCc1cncnc1....
612 3WF6 ic50 = 33 nM FZ9 C18 H16 N6 c1ccc2c(c1....
613 4AU8 ic50 = 551 nM Z3R C11 H8 N2 O2 S3 c1ccc2c(c1....
614 6B16 Ki = 32 nM C7Y C19 H20 N8 C[C@@H](c1....
615 5DFP Ki = 22 nM 59U C28 H32 Cl N7 O CCN1c2c(cn....
616 3FXZ ic50 = 130 nM FLL C30 H18 Cl F N5 O4 Ru c1ccc(cc1)....
617 5IME Ki = 4.6 nM 6BZ C22 H22 Cl N7 O2 CC1=NC=CN(....
618 4ZY6 Ki = 5 nM 4T6 C18 H17 Cl N8 c1cc2c(c(c....
619 3Q53 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
620 4EQC ic50 = 8 nM XR1 C29 H28 Cl N7 O S CCN1c2c(cn....
621 4ZJJ Kd = 9.9 nM 4OR C24 H29 Cl F N5 O CCN1c2ccc(....
622 5KBR ic50 = 260 nM IPW C22 H20 Cl N5 O c1cc(ccc1C....
623 4ZLO ic50 = 12 uM 4PV C18 H18 F2 N4 CN1CCN(CC1....
624 4ZJI Kd = 340 nM 4OQ C20 H22 Cl F N4 CCN1c2ccc(....
625 5DEY Ki = 3.7 nM 59T C25 H25 Cl N6 O3 Cc1cccc(n1....
626 3Q4Z - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
627 4ZY5 Ki = 26 nM 4T5 C17 H25 N7 c1cnc(nc1N....
628 5JZJ - AN2 C10 H16 N6 O9 P2 c1nc(c2c(n....
629 3SLS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
630 5AX9 ic50 = 8 nM 4KT C24 H24 N4 O3 COc1ccc(cc....
631 2J7T - 274 C28 H30 Cl N5 O4 S Cc1c([nH]c....
632 4JQE - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
633 4MWH - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
634 4LFI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
635 3GGF - GVD C22 H19 N7 c1ccc2c(c1....
636 4U44 ic50 = 0.008 uM 3D9 C17 H13 N5 c1ccc(cc1)....
637 4RVT ic50 = 1.9 uM 3XM C17 H19 N O4 CCCCCC(=O)....
638 4OBO ic50 = 0.077 uM 2QV C14 H10 Cl N3 c1cc(cc(c1....
639 3DAK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
640 1CM8 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
641 3EQD - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
642 3EQC - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
643 3EQI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
644 1QL6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
645 1PHK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
646 3M2W ic50 < 0.003 uM L8I C23 H21 F N4 O CN1CC2(C1)....
647 3BHY - 7CP C18 H18 Cl2 N4 O Cn1c2c(ccc....
648 2J90 - IZA C18 H16 F N3 O CC(C)(C)c1....
649 5VJA - DUK C14 H12 Cl N5 O2 S C[C@H](C(=....
650 5A6N ic50 = 52 uM U7E C7 H7 N5 O2 S c1cc(cc(c1....
651 6CMJ ic50 = 5 nM F6J C24 H22 N2 O2 CC(C)Cc1cc....
652 3E7O ic50 = 120 nM 35F C20 H14 N6 O2 c1cc(cc(c1....
653 2VN9 - GVD C22 H19 N7 c1ccc2c(c1....
654 4EJN ic50 = 0.005 uM 0R4 C33 H26 F N7 O2 CC(=O)Nc1c....
655 4WNO ic50 = 160 nM 3RF C20 H19 N7 c1ccc2c(c1....
656 4WNP ic50 = 8 nM 3RJ C22 H20 N8 c1ccc2c(c1....
657 6QAS - 34W C23 H25 F3 N6 O2 CC(=O)NCC(....
658 6MNH - JVD C12 H16 N4 O C[C@H](C(C....
659 5CI7 ic50 = 120 nM 51W C18 H24 I N7 O c1cc(cc(c1....
660 2V7O - DRN C25 H23 N5 O2 S [H]/N=C(/N....
661 2UV2 - GVD C22 H19 N7 c1ccc2c(c1....
662 2JFL - DKI C15 H13 F2 N7 O2 S2 c1cc(c(c(c....
663 3AQV - TAK C24 H25 N5 O c1cc(ccc1c....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: X11; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 X11 1 1
2 JWS 0.404255 0.909091
Similar Ligands (3D)
Ligand no: 1; Ligand: X11; Similar ligands found: 657
No: Ligand Similarity coefficient
1 BZE 0.9847
2 B2T 0.9673
3 JG8 0.9673
4 WOE 0.9638
5 M3E 0.9610
6 6QF 0.9575
7 F2W 0.9543
8 ANC 0.9523
9 BPY 0.9503
10 M1Z 0.9500
11 XDK 0.9483
12 CK2 0.9473
13 AY4 0.9467
14 2GD 0.9467
15 JP2 0.9448
16 0XT 0.9443
17 B4O 0.9436
18 30G 0.9435
19 BZJ 0.9435
20 3J8 0.9432
21 CH9 0.9429
22 GNM 0.9427
23 BNL 0.9423
24 344 0.9417
25 9UL 0.9400
26 1A7 0.9400
27 L22 0.9383
28 ZYR 0.9375
29 PJW 0.9362
30 AN3 0.9359
31 5VL 0.9341
32 0W1 0.9332
33 BIK 0.9318
34 CK1 0.9314
35 1IT 0.9306
36 DPT 0.9305
37 MXD 0.9299
38 4V2 0.9297
39 R20 0.9282
40 GVG 0.9280
41 X48 0.9277
42 TT4 0.9274
43 BQ5 0.9274
44 L5V 0.9272
45 JRB 0.9269
46 MPV 0.9267
47 LJ3 0.9263
48 XM5 0.9261
49 6TZ 0.9261
50 HJH 0.9261
51 9CA 0.9258
52 HQJ 0.9256
53 EN1 0.9255
54 AA 0.9253
55 PEY 0.9251
56 9FL 0.9250
57 NCT 0.9246
58 0BP 0.9243
59 0F9 0.9243
60 THU 0.9240
61 HA5 0.9240
62 1WC 0.9238
63 1KP 0.9238
64 1Z6 0.9237
65 2JK 0.9236
66 X0W 0.9234
67 WVV 0.9232
68 THA 0.9231
69 3PF 0.9227
70 6J9 0.9224
71 5TY 0.9217
72 AJV 0.9215
73 CNI 0.9215
74 DCZ 0.9214
75 V1T 0.9209
76 3Y7 0.9205
77 AJY 0.9201
78 A5H 0.9200
79 FQX 0.9193
80 WUB 0.9191
81 A29 0.9191
82 S60 0.9190
83 1VK 0.9187
84 ESI 0.9182
85 MUK 0.9181
86 4XF 0.9181
87 BPU 0.9176
88 DK1 0.9176
89 5QY 0.9171
90 AUV 0.9171
91 C0H 0.9171
92 BP7 0.9170
93 D48 0.9169
94 28N 0.9169
95 SOV 0.9167
96 HNL 0.9167
97 TIY 0.9167
98 ROI 0.9167
99 ZME 0.9165
100 6HO 0.9162
101 39O 0.9161
102 3QV 0.9161
103 HRM 0.9160
104 78Y 0.9160
105 F16 0.9159
106 DUR 0.9159
107 15N 0.9157
108 AOT 0.9157
109 ZEB 0.9157
110 BGU 0.9154
111 2FQ 0.9152
112 68A 0.9151
113 9FE 0.9150
114 TOF 0.9149
115 ANF 0.9145
116 15E 0.9141
117 E1T 0.9141
118 0FK 0.9140
119 AH9 0.9138
120 DRG 0.9136
121 E35 0.9136
122 IWT 0.9132
123 J5I 0.9132
124 0JD 0.9127
125 THM 0.9127
126 5F8 0.9126
127 DNQ 0.9126
128 46P 0.9125
129 JY4 0.9122
130 D3G 0.9121
131 G3E 0.9120
132 537 0.9119
133 R9G 0.9118
134 DNF 0.9114
135 8G6 0.9113
136 97T 0.9112
137 M5H 0.9112
138 K80 0.9110
139 8HC 0.9104
140 R2P 0.9102
141 FLV 0.9097
142 5AE 0.9096
143 W29 0.9093
144 B21 0.9092
145 GZ2 0.9091
146 7ZL 0.9091
147 2K8 0.9090
148 KTJ 0.9087
149 QUS 0.9086
150 HNK 0.9085
151 SE2 0.9082
152 KTW 0.9080
153 JTA 0.9077
154 6FB 0.9076
155 FHC 0.9075
156 TCR 0.9074
157 GF4 0.9074
158 1HN 0.9071
159 J9Q 0.9069
160 79W 0.9064
161 DX3 0.9064
162 N2Z 0.9062
163 JU2 0.9060
164 SQ7 0.9054
165 7ME 0.9052
166 28A 0.9052
167 92G 0.9051
168 ONR 0.9050
169 H70 0.9050
170 D2G 0.9049
171 FDR 0.9047
172 JR2 0.9047
173 DDU 0.9047
174 6J3 0.9046
175 B86 0.9041
176 G12 0.9037
177 HBO 0.9036
178 E7S 0.9034
179 KW8 0.9029
180 8MO 0.9028
181 5RO 0.9028
182 HHS 0.9028
183 ENO 0.9024
184 JGB 0.9023
185 T2D 0.9021
186 5BT 0.9021
187 OCZ 0.9019
188 X0U 0.9019
189 WSD 0.9018
190 4RU 0.9017
191 CTN 0.9017
192 1ZC 0.9015
193 3D1 0.9015
194 LL1 0.9012
195 LDR 0.9011
196 URI 0.9009
197 9AP 0.9009
198 GNV 0.9007
199 C2Y 0.9007
200 N8Y 0.9007
201 PPY 0.9005
202 C53 0.9005
203 4G2 0.9005
204 0LO 0.9004
205 TIA 0.9003
206 N0Z 0.9002
207 HX4 0.9001
208 KYN 0.9000
209 FCD 0.8999
210 MSR 0.8999
211 4MU 0.8998
212 SRO 0.8995
213 0N7 0.8994
214 S2P 0.8994
215 8NX 0.8992
216 AVA 0.8992
217 226 0.8990
218 ESP 0.8990
219 3RP 0.8990
220 4FF 0.8988
221 LDC 0.8987
222 BEA 0.8987
223 MPK 0.8984
224 DNA 0.8983
225 GO2 0.8982
226 IA2 0.8980
227 5AD 0.8980
228 2O6 0.8979
229 GJP 0.8977
230 49O 0.8976
231 795 0.8972
232 S2T 0.8971
233 8XL 0.8968
234 64C 0.8966
235 VXX 0.8965
236 AR3 0.8964
237 PIY 0.8964
238 KUF 0.8963
239 1L5 0.8961
240 DHZ 0.8958
241 SQ4 0.8958
242 0DN 0.8957
243 ID2 0.8957
244 1SF 0.8957
245 HQD 0.8956
246 CCV 0.8954
247 DX1 0.8954
248 6ZW 0.8954
249 5FL 0.8954
250 FZM 0.8953
251 4LW 0.8953
252 MUA 0.8953
253 8W9 0.8950
254 ESX 0.8949
255 6X9 0.8948
256 BZ2 0.8947
257 0GA 0.8945
258 5UD 0.8945
259 1QP 0.8943
260 7I2 0.8943
261 CB1 0.8943
262 IQQ 0.8941
263 SG2 0.8940
264 9ZE 0.8938
265 K3Y 0.8937
266 KJU 0.8936
267 DIN 0.8936
268 CLZ 0.8935
269 0SY 0.8933
270 EAJ 0.8932
271 RUY 0.8927
272 FF2 0.8922
273 PH2 0.8921
274 JRO 0.8921
275 0HN 0.8921
276 HHR 0.8921
277 UFO 0.8919
278 AMR 0.8919
279 ITE 0.8919
280 1F1 0.8918
281 CTD 0.8917
282 4GU 0.8917
283 VM1 0.8917
284 EGR 0.8916
285 BBY 0.8916
286 6NT 0.8916
287 GNY 0.8915
288 N3W 0.8914
289 CKA 0.8912
290 QBS 0.8910
291 N2M 0.8910
292 II4 0.8910
293 6RQ 0.8909
294 6NI 0.8909
295 2KU 0.8909
296 3NY 0.8907
297 PIM 0.8907
298 982 0.8907
299 3C5 0.8907
300 7UZ 0.8906
301 2D2 0.8906
302 R9Y 0.8906
303 AH3 0.8905
304 MCY 0.8905
305 EXD 0.8904
306 TWO 0.8904
307 DXK 0.8902
308 JAW 0.8902
309 RKV 0.8900
310 URD 0.8897
311 2HC 0.8897
312 CPZ 0.8896
313 KCH 0.8894
314 WS7 0.8894
315 IL5 0.8894
316 0NX 0.8892
317 2LT 0.8892
318 4KL 0.8891
319 BRD 0.8891
320 8ZE 0.8890
321 KT7 0.8889
322 TLF 0.8889
323 5GT 0.8889
324 774 0.8889
325 52C 0.8886
326 43U 0.8884
327 V2Z 0.8884
328 2HU 0.8884
329 0FO 0.8881
330 6BL 0.8880
331 3DT 0.8879
332 0HO 0.8877
333 AZ9 0.8876
334 7VP 0.8876
335 3IL 0.8876
336 6ME 0.8875
337 4JQ 0.8873
338 DQU 0.8872
339 2ZM 0.8871
340 27M 0.8871
341 DAH 0.8870
342 JYB 0.8870
343 Q4G 0.8869
344 PRL 0.8867
345 PUR 0.8867
346 NE1 0.8865
347 F31 0.8865
348 ALE 0.8864
349 4LV 0.8863
350 428 0.8863
351 5F5 0.8863
352 I5A 0.8863
353 5P3 0.8863
354 AH6 0.8862
355 27B 0.8861
356 MUR 0.8860
357 ICB 0.8859
358 Z5P 0.8859
359 61M 0.8857
360 0FR 0.8857
361 UUA 0.8856
362 L5D 0.8851
363 NE2 0.8851
364 JF8 0.8850
365 4BL 0.8849
366 EWG 0.8846
367 CSN 0.8845
368 5NI 0.8844
369 ZRK 0.8844
370 44V 0.8841
371 7B3 0.8841
372 TMG 0.8841
373 ID8 0.8841
374 ZYV 0.8841
375 55D 0.8841
376 9CE 0.8840
377 NFA 0.8840
378 LT2 0.8838
379 1FL 0.8837
380 64E 0.8836
381 173 0.8836
382 5GV 0.8836
383 LLT 0.8836
384 XCG 0.8835
385 J9T 0.8835
386 KYA 0.8834
387 ABI 0.8833
388 TYU 0.8833
389 60L 0.8831
390 2AK 0.8830
391 XHP 0.8830
392 SHI