Receptor
PDB id Resolution Class Description Source Keywords
4YRJ 2.3 Å EC: 6.1.1.21 CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN CO 4-CHLOROBENZENE-1,2-DIAMINE (CHEM 256) TRYPANOSOMA CRUZI (STRAIN CL BRENER) LIGASE AMINOACYL-TRNA SYNTHETASE AARS HISRS TRYPANOSOMA PROTEIN-INHIBITOR COMPLEX LIGASE-LIGASE INHIBITOR COMPLEX
Ref.: A BINDING HOTSPOT IN TRYPANOSOMA CRUZI HISTIDYL-TRN SYNTHETASE REVEALED BY FRAGMENT-BASED CRYSTALLOGRAP COCKTAIL SCREENS. ACTA CRYSTALLOGR. D BIOL. V. 71 1684 2015 CRYSTALLOGR.
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO A:505;
Invalid;
none;
submit data
62.068 C2 H6 O2 C(CO)...
SO4 A:507;
A:508;
A:506;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
DMS A:504;
A:503;
Invalid;
Invalid;
none;
none;
submit data
78.133 C2 H6 O S CS(=O...
4JJ A:502;
Valid;
none;
submit data
142.586 C6 H7 Cl N2 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4YRI 2 Å EC: 6.1.1.21 CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN CO 1-(3-BROMOPHENYL)METHANAMINE (CHEM 166) TRYPANOSOMA CRUZI (STRAIN CL BRENER) LIGASE AMINOACYL-TRNA SYNTHETASE AARS HISRS TRYPANOSOMA PROTEIN-INHIBITOR COMPLEX LIGASE-LIGASE INHIBITOR COMPLEX
Ref.: A BINDING HOTSPOT IN TRYPANOSOMA CRUZI HISTIDYL-TRN SYNTHETASE REVEALED BY FRAGMENT-BASED CRYSTALLOGRAP COCKTAIL SCREENS. ACTA CRYSTALLOGR. D BIOL. V. 71 1684 2015 CRYSTALLOGR.
Members (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4YRI - 4JH C7 H8 Br N c1cc(cc(c1....
2 4YRF - 4HS C5 H4 Br N O C1=CC(=O)N....
3 4YRP - PZH C7 H8 Br N c1cc(ccc1C....
4 4YRC - 0P6 C9 H8 N2 O c1cc2ccc(n....
5 4YRJ - 4JJ C6 H7 Cl N2 c1cc(c(cc1....
6 4YRQ - 4JQ C9 H7 N O2 c1cc2c(cc1....
7 4YP0 - 5IQ C9 H8 N2 c1cc2cnccc....
8 4YRM - 282 C6 H7 N O COc1cccnc1
9 4YRL - 4JM C7 H9 N S CSc1ccc(cc....
10 4YPF - 4FS C9 H8 N2 c1ccc2c(c1....
11 4YRE - 4HR C7 H7 Br O c1ccc(c(c1....
12 4YRN - 4JN C5 H5 Br N2 c1cc(ncc1N....
13 4YRK - 4JL C7 H7 Cl O c1cc(ccc1C....
14 4YRO - 4JO C6 H7 Br N2 Cc1c(ccc(n....
15 4YRR - 691 C11 H10 N2 O CC(=O)Nc1c....
16 4YRG - 4HU C6 H6 Br N O c1cc(nc(c1....
70% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4YRI - 4JH C7 H8 Br N c1cc(cc(c1....
2 4YRF - 4HS C5 H4 Br N O C1=CC(=O)N....
3 4YRP - PZH C7 H8 Br N c1cc(ccc1C....
4 4YRC - 0P6 C9 H8 N2 O c1cc2ccc(n....
5 4YRJ - 4JJ C6 H7 Cl N2 c1cc(c(cc1....
6 4YRQ - 4JQ C9 H7 N O2 c1cc2c(cc1....
7 4YP0 - 5IQ C9 H8 N2 c1cc2cnccc....
8 4YRM - 282 C6 H7 N O COc1cccnc1
9 4YRL - 4JM C7 H9 N S CSc1ccc(cc....
10 4YPF - 4FS C9 H8 N2 c1ccc2c(c1....
11 4YRE - 4HR C7 H7 Br O c1ccc(c(c1....
12 4YRN - 4JN C5 H5 Br N2 c1cc(ncc1N....
13 4YRK - 4JL C7 H7 Cl O c1cc(ccc1C....
14 4YRO - 4JO C6 H7 Br N2 Cc1c(ccc(n....
15 4YRR - 691 C11 H10 N2 O CC(=O)Nc1c....
16 4YRG - 4HU C6 H6 Br N O c1cc(nc(c1....
50% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4YRI - 4JH C7 H8 Br N c1cc(cc(c1....
2 4YRF - 4HS C5 H4 Br N O C1=CC(=O)N....
3 4YRP - PZH C7 H8 Br N c1cc(ccc1C....
4 4YRC - 0P6 C9 H8 N2 O c1cc2ccc(n....
5 4YRJ - 4JJ C6 H7 Cl N2 c1cc(c(cc1....
6 4YRQ - 4JQ C9 H7 N O2 c1cc2c(cc1....
7 4YP0 - 5IQ C9 H8 N2 c1cc2cnccc....
8 4YRM - 282 C6 H7 N O COc1cccnc1
9 4YRL - 4JM C7 H9 N S CSc1ccc(cc....
10 4YPF - 4FS C9 H8 N2 c1ccc2c(c1....
11 4YRE - 4HR C7 H7 Br O c1ccc(c(c1....
12 4YRN - 4JN C5 H5 Br N2 c1cc(ncc1N....
13 4YRK - 4JL C7 H7 Cl O c1cc(ccc1C....
14 4YRO - 4JO C6 H7 Br N2 Cc1c(ccc(n....
15 4YRR - 691 C11 H10 N2 O CC(=O)Nc1c....
16 4YRG - 4HU C6 H6 Br N O c1cc(nc(c1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 4JJ; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 4JJ 1 1
2 5MK 0.411765 0.666667
Similar Ligands (3D)
Ligand no: 1; Ligand: 4JJ; Similar ligands found: 1035
No: Ligand Similarity coefficient
1 XYD 1.0000
2 MCT 1.0000
3 4CL 1.0000
4 JZ2 1.0000
5 BR9 1.0000
6 27Y 1.0000
7 MWJ 1.0000
8 2AC 1.0000
9 MZG 1.0000
10 XBZ 0.9999
11 A1U 0.9995
12 QOS 0.9995
13 4HO 0.9989
14 5JC 0.9982
15 34A 0.9982
16 4ZE 0.9977
17 ICP 0.9975
18 PYD 0.9975
19 TH0 0.9974
20 2YU 0.9969
21 2MP 0.9966
22 MWM 0.9964
23 5MH 0.9962
24 URF 0.9961
25 1MC 0.9956
26 43M 0.9936
27 TDR 0.9928
28 WBU 0.9920
29 TM7 0.9919
30 HT4 0.9913
31 Y8I 0.9913
32 5UC 0.9900
33 4JO 0.9878
34 XYP 0.9873
35 TLD 0.9855
36 LXC 0.9853
37 AHR 0.9828
38 3ZQ 0.9780
39 IUR 0.9761
40 4XR 0.9760
41 1PT 0.9721
42 FPY 0.9711
43 2MH 0.9710
44 40O 0.9709
45 4JU 0.9681
46 CRS 0.9677
47 RCO 0.9677
48 KOJ 0.9673
49 284 0.9673
50 ZZT 0.9672
51 3Z7 0.9663
52 OXE 0.9659
53 3CH 0.9645
54 XYS 0.9643
55 CAQ 0.9641
56 HMH 0.9637
57 LG5 0.9637
58 T6C 0.9633
59 LG3 0.9631
60 URA 0.9626
61 RIP 0.9626
62 CYT 0.9624
63 26D 0.9613
64 B3R 0.9611
65 2CQ 0.9609
66 BVF 0.9600
67 4HS 0.9600
68 M3T 0.9599
69 4ZC 0.9598
70 PXY 0.9598
71 CIG 0.9593
72 L89 0.9590
73 0MK 0.9588
74 HEW 0.9587
75 FUC 0.9587
76 FUL 0.9587
77 NSP 0.9587
78 HX3 0.9585
79 35C 0.9584
80 LG4 0.9584
81 FYU 0.9583
82 4JN 0.9583
83 8GF 0.9583
84 150 0.9582
85 25R 0.9582
86 PCR 0.9582
87 IDH 0.9582
88 24B 0.9580
89 HQE 0.9578
90 BML 0.9574
91 4H2 0.9574
92 2AF 0.9564
93 4CH 0.9562
94 1WG 0.9562
95 8H8 0.9559
96 285 0.9559
97 1DW 0.9554
98 F4Z 0.9553
99 AMC 0.9553
100 BZX 0.9552
101 92Z 0.9547
102 JIF 0.9547
103 HGQ 0.9545
104 PLQ 0.9539
105 FP2 0.9538
106 8LG 0.9537
107 NK 0.9534
108 7MH 0.9533
109 IOL 0.9532
110 1AN 0.9531
111 RSF 0.9531
112 TC7 0.9530
113 23A 0.9526
114 FPI 0.9526
115 HHQ 0.9525
116 G6D 0.9524
117 DFU 0.9523
118 FPN 0.9522
119 DA1 0.9521
120 BEW 0.9521
121 0TR 0.9520
122 76X 0.9520
123 JZ0 0.9518
124 45C 0.9515
125 282 0.9514
126 GLC 0.9513
127 6AI 0.9508
128 TH7 0.9506
129 HBA 0.9504
130 ARB 0.9504
131 2CH 0.9501
132 0R0 0.9492
133 JZ3 0.9491
134 PYG 0.9489
135 93Q 0.9488
136 PHB 0.9487
137 DUC 0.9485
138 7CZ 0.9477
139 HTS 0.9477
140 938 0.9472
141 3XX 0.9471
142 5MI 0.9467
143 TBP 0.9467
144 5MB 0.9466
145 ES9 0.9466
146 TMT 0.9462
147 BTE 0.9459
148 SYN 0.9458
149 11S 0.9456
150 JFD 0.9454
151 H4N 0.9454
152 DEN 0.9454
153 CYH 0.9454
154 DFB 0.9453
155 H3M 0.9448
156 14O 0.9444
157 SWD 0.9444
158 25W 0.9443
159 F81 0.9442
160 HPA 0.9439
161 TMZ 0.9438
162 CXL 0.9438
163 5H1 0.9436
164 4XX 0.9433
165 HBX 0.9430
166 HAI 0.9430
167 ADE 0.9428
168 H8N 0.9427
169 BZF 0.9423
170 10L 0.9421
171 F60 0.9421
172 0R1 0.9420
173 9DA 0.9418
174 RIB 0.9417
175 FK1 0.9416
176 YAN 0.9416
177 2K4 0.9412
178 GVH 0.9412
179 ABN 0.9412
180 3MC 0.9411
181 Q88 0.9409
182 6X8 0.9409
183 IND 0.9407
184 F05 0.9406
185 LZ1 0.9404
186 HPY 0.9400
187 XXR 0.9400
188 CWM 0.9398
189 V55 0.9397
190 BZI 0.9396
191 6MP 0.9394
192 AX7 0.9394
193 PYF 0.9393
194 ES0 0.9393
195 PY7 0.9393
196 HMU 0.9390
197 FCA 0.9390
198 4M4 0.9390
199 3CE 0.9389
200 ADZ 0.9384
201 270 0.9384
202 6MH 0.9383
203 2MI 0.9382
204 9HX 0.9381
205 DUB 0.9381
206 ECE 0.9380
207 GCS 0.9380
208 MPI 0.9379
209 4VP 0.9379
210 7HP 0.9376
211 7WA 0.9375
212 J1Z 0.9375
213 XQ0 0.9373
214 0CT 0.9370
215 ABE 0.9370
216 1XX 0.9370
217 C2B 0.9369
218 NOJ 0.9367
219 TM4 0.9366
220 ABV 0.9366
221 PM6 0.9366
222 3FA 0.9366
223 MBD 0.9363
224 275 0.9355
225 2C9 0.9354
226 ES4 0.9354
227 2CM 0.9350
228 1MR 0.9350
229 1P7 0.9349
230 IDM 0.9348
231 GMN 0.9347
232 SOE 0.9345
233 8NY 0.9344
234 BGC 0.9342
235 P3K 0.9339
236 9EW 0.9338
237 DGJ 0.9337
238 HIU 0.9337
239 GXE 0.9336
240 4HM 0.9336
241 2MY 0.9333
242 7B4 0.9332
243 FLM 0.9329
244 4JP 0.9328
245 FFP 0.9324
246 9X7 0.9321
247 YCP 0.9320
248 S76 0.9318
249 BP1 0.9317
250 F0J 0.9315
251 HLR 0.9314
252 IPH 0.9313
253 286 0.9311
254 ISN 0.9311
255 SAL 0.9311
256 0RW 0.9310
257 FUF 0.9307
258 5B1 0.9305
259 GAL 0.9305
260 BEN 0.9303
261 6CS 0.9303
262 BEZ 0.9302
263 64K 0.9298
264 MLT 0.9297
265 2DR 0.9297
266 M1A 0.9291
267 F5B 0.9289
268 ICC 0.9287
269 2D0 0.9286
270 C2A 0.9286
271 4JL 0.9284
272 CYS 0.9283
273 MBN 0.9282
274 FBA 0.9280
275 G4D 0.9280
276 G3F 0.9279
277 7W4 0.9278
278 KKN 0.9278
279 SVN 0.9278
280 EUG 0.9275
281 23W 0.9271
282 JB5 0.9269
283 JZ1 0.9269
284 IFM 0.9269
285 R2B 0.9268
286 WOT 0.9263
287 8CL 0.9262
288 AZF 0.9260
289 5AN 0.9259
290 DTL 0.9259
291 ES7 0.9258
292 OXQ 0.9257
293 QUZ 0.9256
294 AX2 0.9255
295 NPY 0.9254
296 TTO 0.9254
297 YHO 0.9254
298 NCA 0.9252
299 FE DB1 0.9251
300 2A9 0.9250
301 6M4 0.9250
302 RAM 0.9250
303 6M9 0.9248
304 NOY 0.9248
305 GBD 0.9247
306 3AP 0.9246
307 NEQ 0.9244
308 5ZE 0.9243
309 1SQ 0.9241
310 3DM 0.9241
311 5WV 0.9240
312 2IM 0.9240
313 G2F 0.9239
314 DBH 0.9238
315 3HA 0.9238
316 4AP 0.9237
317 9CL 0.9235
318 BR8 0.9235
319 5Q0 0.9234
320 2ZX 0.9234
321 94N 0.9234
322 8S0 0.9234
323 3F0 0.9233
324 OXZ 0.9233
325 HGW 0.9231
326 1AB 0.9230
327 GYE 0.9230
328 XM0 0.9229
329 1LQ 0.9228
330 67N 0.9228
331 13X 0.9228
332 3MH 0.9227
333 2AP 0.9227
334 HHN 0.9227
335 LMR 0.9226
336 7HQ 0.9225
337 2AQ 0.9225
338 ES5 0.9225
339 HVK 0.9224
340 6UA 0.9224
341 5NU 0.9223
342 JAE 0.9222
343 JPZ 0.9222
344 1NP 0.9222
345 4JM 0.9222
346 6HQ 0.9222
347 FCB 0.9222
348 4FS 0.9221
349 HQY 0.9220
350 BE2 0.9220
351 5SG 0.9219
352 4NC 0.9219
353 4YS 0.9218
354 WDL 0.9218
355 PIH 0.9218
356 LDU 0.9218
357 ES1 0.9217
358 O72 0.9217
359 5IQ 0.9217
360 HRZ 0.9216
361 24W 0.9216
362 NBZ 0.9215
363 1LM 0.9214
364 3M0 0.9211
365 COU 0.9211
366 JZ9 0.9210
367 DHB 0.9209
368 6PC 0.9209
369 5XC 0.9208
370 03V 0.9208
371 JBH 0.9202
372 MB3 0.9202
373 OHG 0.9202
374 3AY 0.9201
375 B53 0.9201
376 NIO 0.9201
377 9PO 0.9200
378 280 0.9200
379 2KT 0.9198
380 1DH 0.9198
381 EXO 0.9198
382 KIV 0.9198
383 ARA 0.9196
384 INO 0.9195
385 3DO 0.9195
386 3U4 0.9194
387 FAN 0.9192
388 RM1 0.9192
389 BAM 0.9191
390 2A7 0.9190
391 25T 0.9190
392 4A3 0.9189
393 MAK 0.9188
394 LZM 0.9188
395 I3A 0.9187
396 LGA 0.9185
397 24T 0.9185
398 5CU 0.9184
399 KG7 0.9183
400 OAA 0.9183
401 ES6 0.9182
402 42A 0.9182
403 N5J 0.9181
404 IF7 0.9179
405 261 0.9179
406 YTB 0.9179
407 2EC 0.9179
408 NNO 0.9178
409 E60 0.9178
410 LDP 0.9178
411 BHA 0.9177
412 3HM 0.9177
413 GUN 0.9176
414 5RG 0.9175
415 4CS 0.9175
416 DSN 0.9175
417 AZA 0.9174
418 OCH 0.9173
419 ERH 0.9173
420 EDG 0.9172
421 12M 0.9172
422 4M0 0.9171
423 DOB 0.9171
424 H42 0.9171
425 2HO 0.9170
426 1XM 0.9170
427 3ID 0.9169
428 2H5 0.9169
429 GAG 0.9168
430 XX2 0.9168
431 9DG 0.9167
432 PYJ 0.9167
433 FA0 0.9166
434 MFB 0.9166
435 93K 0.9165
436 RNS 0.9165
437 8GC 0.9163
438 GTQ 0.9161
439 BSX 0.9160
440 ASO 0.9160
441 82I 0.9160
442 HY3 0.9160
443 L3Q 0.9159
444 MZW 0.9158
445 BP9 0.9158
446 RM4 0.9158
447 2XX 0.9156
448 PZA 0.9156
449 4SV 0.9155
450 MYJ 0.9153
451 FHB 0.9152
452 AC0 0.9152
453 P9P 0.9151
454 IFL 0.9150
455 KSW 0.9150
456 2FG 0.9150
457 5M0 0.9149
458 3PY 0.9148
459 YH7 0.9147
460 HSE 0.9147
461 6AP 0.9146
462 DTI 0.9145
463 717 0.9142
464 60P 0.9141
465 VGL 0.9141
466 CEJ 0.9140
467 DGY 0.9140
468 HH8 0.9138
469 VAL 0.9138
470 TP5 0.9137
471 XAN 0.9137
472 3RK 0.9137
473 265 0.9136
474 PRO 0.9136
475 DMD 0.9135
476 SX1 0.9135
477 BOA 0.9135
478 2CK 0.9134
479 GAB 0.9133
480 APY 0.9130
481 FOA 0.9130
482 9TZ 0.9130
483 5AC 0.9128
484 3HB 0.9126
485 RP7 0.9125
486 UNU 0.9124
487 54G 0.9123
488 DMG 0.9123
489 1DU 0.9123
490 FP1 0.9122
491 4XH 0.9120
492 BE7 0.9120
493 93B 0.9120
494 SER 0.9120
495 7EX 0.9120
496 R8S 0.9119
497 53C 0.9118
498 2PC 0.9117
499 DTU 0.9116
500 RSO 0.9116
501 GIV 0.9115
502 B24 0.9113
503 R8A 0.9112
504 9TW 0.9110
505 NTN 0.9108
506 SS1 0.9108
507 0CU 0.9106
508 HSL 0.9106
509 14J 0.9105
510 BZ3 0.9105
511 TCZ 0.9105
512 QSB 0.9105
513 149 0.9104
514 A2Q 0.9100
515 CHB 0.9099
516 PYC 0.9098
517 A2F 0.9097
518 IT2 0.9097
519 IGA 0.9095
520 PEA 0.9095
521 DXX 0.9092
522 FDB 0.9091
523 MR1 0.9091
524 5HN 0.9090
525 ADK 0.9089
526 3AB 0.9089
527 VNJ 0.9088
528 5VM 0.9086
529 5OB 0.9085
530 H76 0.9085
531 290 0.9082
532 141 0.9082
533 GLA 0.9081
534 BCP 0.9080
535 ZZ3 0.9079
536 HH5 0.9077
537 36R 0.9075
538 BTY 0.9072
539 3MA 0.9070
540 LCN 0.9070
541 B55 0.9070
542 AGK 0.9069
543 JBE 0.9068
544 BHO 0.9068
545 PCA 0.9068
546 URQ 0.9068
547 QSC 0.9066
548 SMV 0.9066
549 0P6 0.9063
550 7VJ 0.9063
551 DX4 0.9061
552 AZG 0.9060
553 L60 0.9060
554 GIF 0.9060
555 CWS 0.9060
556 CIZ 0.9060
557 3NT 0.9059
558 47J 0.9058
559 KUF 0.9057
560 MMZ 0.9056
561 MLI 0.9054
562 NPO 0.9053
563 KJY 0.9052
564 278 0.9052
565 FQI 0.9050
566 LRH 0.9050
567 URC 0.9049
568 8TX 0.9049
569 XIY 0.9049
570 MZ0 0.9048
571 KT7 0.9047
572 IPB 0.9046
573 ISE 0.9044
574 KYD 0.9043
575 69O 0.9041
576 MNM 0.9041
577 C5J 0.9040
578 X6X 0.9040
579 JAB 0.9039
580 1P8 0.9038
581 CLW 0.9038
582 WCE 0.9037
583 OVV 0.9036
584 NIZ 0.9035
585 F9Y 0.9034
586 PBC 0.9034
587 XQG 0.9034
588 HYN 0.9034
589 PZI 0.9034
590 1XN 0.9033
591 JBN 0.9033
592 5CL 0.9033
593 ET2 0.9033
594 MAN 0.9032
595 CFP 0.9030
596 1WD 0.9028
597 EQT 0.9025
598 75K 0.9023
599 NMJ 0.9023
600 JKE 0.9022
601 6LW 0.9022
602 GIO 0.9021
603 DAB 0.9018
604 MLA 0.9018
605 ALL 0.9017
606 NVI 0.9015
607 PAB 0.9015
608 86J 0.9012
609 IHB 0.9012
610 TZC 0.9011
611 HHA 0.9010
612 ES2 0.9008
613 M58 0.9008
614 8CM 0.9006
615 ASN 0.9005
616 8WO 0.9005
617 M2H 0.9004
618 3BZ 0.9003
619 9TY 0.9003
620 TAR 0.9003
621 B57 0.9002
622 FBB 0.9000
623 PXL 0.9000
624 DMI 0.8999
625 GAF 0.8999
626 M1E 0.8998
627 1M2 0.8997
628 3SK 0.8997
629 ASP 0.8997
630 IMR 0.8996
631 P72 0.8996
632 QBK 0.8995
633 GXL 0.8995
634 9MG 0.8994
635 K2T 0.8993
636 DIE 0.8992
637 1Y6 0.8992
638 273 0.8992
639 AC6 0.8991
640 0W8 0.8989
641 8WT 0.8987
642 RUU 0.8987
643 XBT 0.8987
644 R1X 0.8984
645 2LP 0.8983
646 9YL 0.8983
647 8IG 0.8982
648 INS 0.8982
649 MRY 0.8981
650 DMJ 0.8980
651 XAZ 0.8980
652 HBD 0.8980
653 GOO 0.8980
654 C21 0.8978
655 VGD 0.8978
656 DHK 0.8978
657 ABA 0.8977
658 PBZ 0.8977
659 1GN 0.8977
660 A7W 0.8976
661 5JL 0.8975
662 HCS 0.8974
663 XIX 0.8973
664 BRT 0.8972
665 LGC 0.8972
666 QWN 0.8971
667 BVC 0.8970
668 CXF 0.8970
669 LER 0.8969
670 ISZ 0.8967
671 VNL 0.8966
672 TFB 0.8966
673 CRN 0.8965
674 PXM 0.8964
675 3OC 0.8964
676 PAF 0.8964
677 VOH 0.8963
678 MRW 0.8961
679 YIO 0.8961
680 PA1 0.8961
681 QXW 0.8958
682 P92 0.8957
683 URP 0.8957
684 Z82 0.8956
685 MBG 0.8956
686 2HQ 0.8951
687 2ZV 0.8950
688 Z6J 0.8950
689 O7U 0.8950
690 6F0 0.8950
691 MEW 0.8949
692 V1L 0.8947
693 4MA 0.8946
694 42J 0.8946
695 7WV 0.8945
696 XRG 0.8944
697 GRE 0.8944
698 5JQ 0.8943
699 4FA 0.8938
700 GXY 0.8937
701 ALO 0.8935
702 E7Z 0.8934
703 R8V 0.8934
704 WOO 0.8933
705 IP0 0.8933
706 FUB 0.8932
707 PE0 0.8932
708 260 0.8928
709 PFB 0.8927
710 FRU 0.8920
711 4AA 0.8918
712 SEJ 0.8918
713 FOT 0.8917
714 MET 0.8917
715 SWA 0.8917
716 SHG 0.8916
717 3Z8 0.8916
718 MAE 0.8916
719 1P3 0.8916
720 12Q 0.8914
721 ZBT 0.8914
722 6M1 0.8913
723 7W1 0.8912
724 4JT 0.8910
725 4AX 0.8910
726 HSM 0.8910
727 EV0 0.8908
728 THR 0.8908
729 7WG 0.8906
730 IV2 0.8905
731 F31 0.8905
732 BMA 0.8905
733 JBK 0.8904
734 DIN 0.8903
735 2BG 0.8901
736 PEL 0.8900
737 39A 0.8896
738 AZ8 0.8892
739 UNC 0.8892
740 KBG 0.8892
741 FDK 0.8892
742 Q24 0.8891
743 FBM 0.8891
744 GDE 0.8889
745 826 0.8888
746 32O 0.8887
747 5QX 0.8883
748 AEF 0.8881
749 CFI 0.8881
750 PRY 0.8880
751 ITN 0.8879
752 BBF 0.8878
753 BCF 0.8877
754 174 0.8877
755 ORO 0.8875
756 UGC 0.8874
757 HIO 0.8874
758 OXC 0.8873
759 BNS 0.8873
760 HVQ 0.8868
761 SS2 0.8864
762 AQO 0.8864
763 M5K 0.8863
764 SW7 0.8863
765 PZM 0.8863
766 SJ5 0.8862
767 95Z 0.8861
768 32X 0.8859
769 FPK 0.8856
770 HQT 0.8854
771 MWP 0.8854
772 P2D 0.8853
773 G5V 0.8853
774 XUL 0.8852
775 HJP 0.8852
776 HFB 0.8851
777 HXX 0.8851
778 8ZE 0.8851
779 M6N 0.8848
780 DOR 0.8846
781 MSN 0.8844
782 BVG 0.8843
783 AFR 0.8842
784 FLA 0.8842
785 BDP 0.8841
786 AUD 0.8841
787 JZ7 0.8840
788 6GU 0.8840
789 KPL 0.8839
790 SHA 0.8839
791 SKA 0.8836
792 CGB 0.8835
793 IBF 0.8830
794 ZXD 0.8830
795 DPR 0.8828
796 ICO 0.8825
797 NVA 0.8824
798 YRL 0.8823
799 TTL 0.8823
800 GLU 0.8823
801 3SL 0.8820
802 SKM 0.8820
803 2RA 0.8815
804 A65 0.8815
805 C2U 0.8813
806 JZ4 0.8812
807 AJ2 0.8811
808 ORN 0.8811
809 NBE 0.8808
810 34D 0.8807
811 J9W 0.8807
812 5RN 0.8807
813 4XV 0.8805
814 PCI 0.8805
815 NDM 0.8803
816 M1Q 0.8803
817 1U6 0.8802
818 7MU 0.8801
819 4HC 0.8801
820 IJZ 0.8801
821 40E 0.8801
822 AW5 0.8800
823 DCY 0.8799
824 DRL 0.8798
825 0JD 0.8797
826 F3B 0.8796
827 KMT 0.8796
828 5WX 0.8794
829 BDF 0.8794
830 FH2 0.8793
831 HY1 0.8789
832 MO8 0.8789
833 4XS 0.8789
834 DQN 0.8788
835 MQN 0.8786
836 4Z4 0.8786
837 D1X 0.8786
838 94B 0.8785
839 DBB 0.8784
840 KIB 0.8782
841 OK7 0.8780
842 TEO 0.8776
843 G3E 0.8776
844 CTL 0.8776
845 SRT 0.8775
846 DAS 0.8773
847 KJH 0.8771
848 TZE 0.8771
849 PKU 0.8766
850 UEG 0.8766
851 I1N 0.8766
852 GLF 0.8765
853 M1H 0.8765
854 TPA 0.8765
855 DHS 0.8764
856 MT0 0.8763
857 DIU 0.8761
858 AAE 0.8760
859 RHU 0.8760
860 948 0.8760
861 F9P 0.8760
862 TLA 0.8758
863 3WA 0.8757
864 NXA 0.8756
865 QSH 0.8755
866 DYA 0.8754
867 M0W 0.8753
868 Q6T 0.8752
869 LYL 0.8751
870 3V4 0.8751
871 EA1 0.8749
872 HZQ 0.8749
873 3PF 0.8749
874 EKZ 0.8748
875 ZWZ 0.8747
876 4PW 0.8746
877 42C 0.8745
878 2AL 0.8745
879 IPZ 0.8743
880 4YO 0.8742
881 7NI 0.8740
882 0TU 0.8740
883 FGZ 0.8740
884 CN0 0.8737
885 JBQ 0.8735
886 UY7 0.8735
887 5RO 0.8735
888 SIN 0.8733
889 SR1 0.8733
890 TIU 0.8732
891 ODV 0.8732
892 EOL 0.8731
893 1LN 0.8731
894 7VS 0.8729
895 4P5 0.8729
896 7N0 0.8729
897 KDV 0.8723
898 AEH 0.8723
899 JZ5 0.8722
900 5QY 0.8722
901 HLZ 0.8721
902 6RQ 0.8721
903 3IT 0.8720
904 H7Y 0.8720
905 RB5 0.8720
906 4JQ 0.8719
907 X0V 0.8719
908 LT2 0.8717
909 3MT 0.8716
910 ILE 0.8714
911 N2I 0.8714
912 J5I 0.8711
913 0HO 0.8711
914 ARW 0.8711
915 CEE 0.8710
916 TFU 0.8710
917 HYP 0.8709
918 SE2 0.8708
919 IFP 0.8708
920 JND 0.8707
921 495 0.8707
922 4SX 0.8707
923 MRZ 0.8706
924 KJU 0.8706
925 DHR 0.8704
926 M0Q 0.8704
927 51F 0.8702
928 DIG 0.8700
929 AKH 0.8700
930 BAE 0.8697
931 DHQ 0.8696
932 3R6 0.8695
933 192 0.8695
934 LNR 0.8694
935 JA8 0.8693
936 XHP 0.8691
937 B62 0.8690
938 MUA 0.8689
939 1AC 0.8689
940 SOR 0.8689
941 PEP 0.8688
942 OTW 0.8685
943 1F1 0.8685
944 FBV 0.8680
945 DBJ 0.8677
946 3MB 0.8676
947 173 0.8676
948 D48 0.8675
949 XYL 0.8670
950 0HN 0.8669
951 GLT 0.8669
952 OXM 0.8669
953 OVM 0.8668
954 1DV 0.8668
955 OW4 0.8664
956 PHU 0.8662
957 HDA 0.8662
958 FA1 0.8660
959 0FO 0.8659
960 EYK 0.8659
961 OXD 0.8659
962 44W 0.8653
963 4ZA 0.8651
964 PYR 0.8651
965 PBE 0.8650
966 AMT 0.8645
967 3NY 0.8644
968 PQ0 0.8643
969 N8Y 0.8639
970 AKB 0.8639
971 SF9 0.8639
972 DBX 0.8638
973 TWO 0.8637
974 DQU 0.8636
975 4WL 0.8635
976 5GU 0.8631
977 B60 0.8630
978 6NT 0.8630
979 ABI 0.8625
980 BAQ 0.8625
981 PRF 0.8625
982 SN4 0.8621
983 ATQ 0.8620
984 3A9 0.8620
985 XCZ 0.8619
986 ASC 0.8618
987 XLS 0.8616
988 LFR 0.8615
989 2MN 0.8615
990 AZ9 0.8614
991 680 0.8607
992 6KX 0.8605
993 1DQ 0.8603
994 HQD 0.8601
995 QWW 0.8595
996 MVN 0.8595
997 LSA 0.8593
998 MFU 0.8590
999 069 0.8590
1000 UAN 0.8588
1001 QX4 0.8587
1002 PYQ 0.8582
1003 2ZM 0.8582
1004 SFU 0.8580
1005 TSS 0.8580
1006 ADA 0.8580
1007 4MZ 0.8579
1008 PBR 0.8576
1009 DNF 0.8574
1010 N8P 0.8572
1011 TEP 0.8571
1012 4FH 0.8571
1013 QY9 0.8570
1014 ANN 0.8568
1015 SXS 0.8567
1016 6NI 0.8567
1017 44V 0.8559
1018 6ME 0.8557
1019 L99 0.8553
1020 APZ 0.8552
1021 JAW 0.8552
1022 QX2 0.8551
1023 2HU 0.8548
1024 IQ0 0.8544
1025 PRZ 0.8543
1026 5MP 0.8541
1027 NDH 0.8540
1028 259 0.8540
1029 51R 0.8538
1030 7WR 0.8535
1031 SYV 0.8535
1032 OVP 0.8533
1033 12B 0.8525
1034 YSO 0.8525
1035 JXN 0.8503
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4YRI; Ligand: 4JH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4yri.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4YRI; Ligand: 4JH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4yri.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback