Receptor
PDB id Resolution Class Description Source Keywords
5E9I 1.96 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF BAZ2B BROMODOMAIN IN COMPLEX WITH FRAGM HOMO SAPIENS FOUR HELICAL BUNDLE TRANSCRIPTION
Ref.: HIGH-THROUGHPUT FRAGMENT DOCKING INTO THE BAZ2B BRO EFFICIENT IN SILICO SCREENING FOR X-RAY CRYSTALLOGR ACS CHEM.BIOL. V. 11 800 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
F60 A:2001;
Valid;
none;
submit data
133.147 C8 H7 N O c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4XUB 1.98 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN BAZ2B IN COMPL BAZ2-ICR CHEMICAL PROBE HOMO SAPIENS TRANSCRIPTION BROMODOMAIN ACETYLATED LYSINE BINDING PROTEIKIAA1476 WALP4 SGC STRUCTURAL GENOMICS CONSORTIUM
Ref.: STRUCTURE ENABLED DESIGN OF BAZ2-ICR, A CHEMICAL PR TARGETING THE BROMODOMAINS OF BAZ2A AND BAZ2B. J.MED.CHEM. V. 58 2553 2015
Members (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 4XUB ic50 = 1.07 uM 43D C19 H18 N8 Cc1cn(nn1)....
2 4XUA ic50 = 26 uM 43C C21 H18 N6 Cc1cn(nn1)....
3 5MGF Kd = 54 uM 7MW C9 H11 N O3 CCC(=O)c1c....
4 5E9I - F60 C8 H7 N O c1cc(cc2c1....
5 6FGT - D9T C14 H21 N3 O2 CN1C=C(C=C....
6 4NRB ic50 = 38 uM 2LX C13 H17 N O3 CNC(=O)c1c....
7 6FH6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
8 5MGG - 7MU C7 H7 Cl N2 O CNC(=O)c1c....
9 5ORB - JR6 C16 H19 N3 O2 S Cn1c(c2c(n....
10 4NRC ic50 = 241 uM 2LY C8 H9 N O3 S CNC(=O)c1c....
11 6FH7 - EN2 C17 H18 F N3 O3 CN1C=C(C=C....
12 5E9K - 5KX C3 H3 Cl N2 c1cnc([nH]....
13 4NRA Kd = 65 uM 2LW C13 H13 Cl N2 O CC(=O)N1CC....
14 5MGE Kd = 87 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
15 4NR9 - ALY C8 H16 N2 O3 CC(=O)NCCC....
16 5E9L - 6AI C7 H7 N3 c1cc2cn[nH....
17 5OR9 ic50 = 88 uM JR5 C18 H21 F N4 O3 S Cn1c(c2c(n....
18 5E74 Kd = 39 uM 5KH C25 H19 F3 N2 O3 Cc1ccc(cc1....
19 5E9M - BAE C6 H13 N O CC(C)(C)C(....
20 6FGU - D9Q C13 H19 N3 O2 CN1C=C(C=C....
21 5DYX - ADE C5 H5 N5 c1[nH]c2c(....
22 5DYU - MZ0 C4 H6 N2 O c1c([nH]cn....
23 5E73 Kd = 23 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
70% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 4XUB ic50 = 1.07 uM 43D C19 H18 N8 Cc1cn(nn1)....
2 4XUA ic50 = 26 uM 43C C21 H18 N6 Cc1cn(nn1)....
3 5MGF Kd = 54 uM 7MW C9 H11 N O3 CCC(=O)c1c....
4 5E9I - F60 C8 H7 N O c1cc(cc2c1....
5 6FGT - D9T C14 H21 N3 O2 CN1C=C(C=C....
6 4NRB ic50 = 38 uM 2LX C13 H17 N O3 CNC(=O)c1c....
7 6FH6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
8 5MGG - 7MU C7 H7 Cl N2 O CNC(=O)c1c....
9 5ORB - JR6 C16 H19 N3 O2 S Cn1c(c2c(n....
10 4NRC ic50 = 241 uM 2LY C8 H9 N O3 S CNC(=O)c1c....
11 6FH7 - EN2 C17 H18 F N3 O3 CN1C=C(C=C....
12 5E9K - 5KX C3 H3 Cl N2 c1cnc([nH]....
13 4NRA Kd = 65 uM 2LW C13 H13 Cl N2 O CC(=O)N1CC....
14 5MGE Kd = 87 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
15 4NR9 - ALY C8 H16 N2 O3 CC(=O)NCCC....
16 5E9L - 6AI C7 H7 N3 c1cc2cn[nH....
17 5OR9 ic50 = 88 uM JR5 C18 H21 F N4 O3 S Cn1c(c2c(n....
18 5E74 Kd = 39 uM 5KH C25 H19 F3 N2 O3 Cc1ccc(cc1....
19 5E9M - BAE C6 H13 N O CC(C)(C)C(....
20 6FGU - D9Q C13 H19 N3 O2 CN1C=C(C=C....
21 5DYX - ADE C5 H5 N5 c1[nH]c2c(....
22 5DYU - MZ0 C4 H6 N2 O c1c([nH]cn....
23 5E73 Kd = 23 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
50% Homology Family (389)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6JJ3 ic50 = 100 nM BS6 C23 H25 N5 O4 S CN1CCN(CC1....
2 6P05 ic50 = 5.9 nM YF2 C30 H28 N6 O3 S CCS(=O)(=O....
3 4IOO - BAE C6 H13 N O CC(C)(C)C(....
4 5I88 Kd = 250 nM 69G C20 H21 N3 O2 C/C=C/CN1C....
5 5DX4 Kd = 0.137 uM E0C C20 H17 Br N2 O4 S CCN1c2ccc(....
6 6JJB ic50 = 49.5 nM BT0 C19 H16 N2 O4 S CN1c2ccc(c....
7 3JVK Kd = 118 uM GLY GLY ALY ALA PRO ARG LYS GLN n/a n/a
8 4HBX ic50 = 1.9 uM 14X C13 H17 N3 O3 S CN1Cc2cc(c....
9 4NUE Ki = 0.15 uM NUE C19 H19 N5 O3 S Cc1cc(c(c(....
10 6SB8 Kd = 0.07 uM L45 C21 H27 N3 O5 S CCN(CC)S(=....
11 5Y94 Kd = 164 nM 8QC C16 H16 Br N3 O4 S Cc1c2cc(c(....
12 6DMJ - 53W C27 H32 N4 O3 Cc1c(c(on1....
13 4HXR ic50 = 4.1 uM 1A4 C13 H10 N2 O3 S3 c1cc(cc(c1....
14 6DML - 9BM C25 H26 N4 O4 Cc1c(c(on1....
15 5TI5 ic50 = 41 uM 7CN C16 H13 Br N2 O3 S c1cc(cc(c1....
16 6VUJ ic50 = 35.2 uM RLY C23 H30 N2 O5 S CCN(CC)S(=....
17 6X7B ic50 = 27 nM ZVP C26 H24 N4 O5 S c1cc(cnc1)....
18 4O7C ic50 = 10 uM 2RK C22 H23 N5 O C1CNCCC1C2....
19 4IOQ - BAQ C4 H7 N O C1CC(=O)NC....
20 4HXK - 1AJ C11 H11 N3 O S c1csc2c1CN....
21 6S6K Kd = 0.18 uM KXK C24 H31 N3 O5 S Cc1c2c(c([....
22 2YEL ic50 = 15.5 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
23 6RWJ Kd = 6.41 uM KLK C12 H16 N2 O2 Cc1c2c(c([....
24 6SA2 Kd = 0.08 uM L25 C22 H27 N3 O6 S Cc1c2c(c([....
25 6XV7 - O2Q C14 H13 F2 N5 Cc1nnc2n1n....
26 4BW4 ic50 = 631 nM 9B6 C22 H16 F3 N5 O4 Cc1c(c(on1....
27 4O72 ic50 = 1 uM 2R4 C25 H19 N O3 S c1ccc2c(c1....
28 5F63 Kd = 12 nM 5W2 C28 H35 Cl F N7 O3 S Cc1cnc(nc1....
29 5HLS ic50 = 0.039 uM 62G C20 H16 Cl N3 O2 Cc1c-2c(on....
30 4HBW ic50 = 4.8 uM 14Z C11 H15 N3 O3 S CCNS(=O)(=....
31 4OGI Kd = 37 nM R78 C28 H39 N7 O3 CC[C@@H]1C....
32 6WW8 - YR0 C31 H32 N6 O4 S CN(C)C(=O)....
33 5TI7 ic50 = 11 uM 7CQ C17 H19 Br N2 O4 S COc1ccc(cc....
34 4J0S ic50 = 0.382 uM 1H3 C18 H17 N O3 Cc1c(c(on1....
35 6Q3Y Kd = 54 nM HG5 C30 H38 N6 O2 CC[C@@H]1C....
36 6SAJ Kd = 0.05 uM L2Z C23 H27 N3 O6 S Cc1c2c(c([....
37 4F3I Kd = 36.1 nM 0S6 C20 H19 Cl N4 O2 S Cc1c(sc-2c....
38 4QZS Kd = 89 nM JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
39 6AFR ic50 = 70 nM 9E3 C13 H10 F N3 O c1cc2c(ccc....
40 4WIV Kd = 550 nM 3P2 C21 H23 N5 O Cc1c(c(on1....
41 6VUF ic50 = 147 uM RLV C14 H20 N2 O3 S CCCNS(=O)(....
42 3P5O Kd = 55.2 nM EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
43 4UIX ic50 = 0.00000001 M TVU C22 H24 N2 O6 S2 CN1C=C(c2c....
44 4HXS ic50 = 4.1 uM 1A3 C16 H14 N2 O3 S2 c1ccc(cc1)....
45 5HM0 ic50 = 0.44 uM 62V C18 H13 Cl N2 O Cc1c-2c(on....
46 5DLX Kd = 2 uM 5D2 C25 H33 Cl N8 O Cc1nnc2n1n....
47 5TI2 ic50 = 24 uM 7CJ C16 H15 F N2 O3 S c1cc(cc(c1....
48 5D3H Kd = 7.9 uM 57G C20 H27 N3 O6 S CCc1c(c([n....
49 6E4A Kd = 44 nM HRY C29 H34 Cl N7 O CN1C=C(C=C....
50 4MEP ic50 = 4.7 uM 24Y C19 H14 Cl N5 O Cc1cccnc1n....
51 4YH4 ic50 = 26 uM Y81 C20 H15 N3 O2 c1ccc(cc1)....
52 5D3N Kd = 9.2 uM L40 C18 H23 N3 O4 S CCc1c(c([n....
53 6C7R Kd = 2.2 nM EO4 C24 H25 N7 O2 Cc1c(c(on1....
54 6WGX ic50 = 0.15 uM U0D C31 H36 F3 N7 Cc1cc(cc(c....
55 6HOV - FER C10 H10 O4 COc1cc(ccc....
56 5D26 Kd = 0.81 uM L28 C19 H26 N4 O5 S CCc1c(c([n....
57 3MUK Kd = 380 uM ALA THR PRK ALA ALA ARG LYS SER n/a n/a
58 4J3I Kd = 8.93 uM 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
59 6X7D ic50 = 388 nM UT4 C19 H18 N2 O4 S c1cc2c(cc1....
60 4QB3 Kd = 3.4 uM 30M C17 H21 N3 O2 CC(=O)NCCC....
61 4LZS Kd = 16 uM L46 C11 H16 N2 O2 CCc1c(c([n....
62 6HDQ ic50 = 5.01 uM FZE C30 H37 F2 N5 O Cc1cc(cnc1....
63 4O71 ic50 = 18 uM CPB C21 H20 Cl N O5 C[N@]1CC[C....
64 4CFL Kd = 1.33 uM 8DQ C19 H18 N2 O2 c1ccc(cc1)....
65 4C67 - L5S C15 H12 N4 S Cc1nnc2n1-....
66 6V1K - 5SW C20 H23 N3 O3 CN1C=C(c2c....
67 4QR3 ic50 = 1.4 uM BNJ C14 H16 N2 O3 S2 c1cc(cc(c1....
68 4ZC9 - 4MW C38 H37 Cl N8 O7 S Cc1c(sc-2c....
69 4MEO - 25V C18 H16 N2 O2 Cc1cc(c2cc....
70 6UVM Kd = 510 uM QJA C11 H13 N O S2 CC(=O)N1CC....
71 4LRG ic50 = 0.026 uM 1XB C20 H18 Cl N3 O2 S Cc1c(sc-2c....
72 6CKS ic50 = 0.015 uM F5Y C23 H23 N3 O4 S CCS(=O)(=O....
73 6DJC Ki = 232.8 nM CF6 C48 H54 Cl2 N10 O2 S2 Cc1c(sc-2c....
74 5TI3 ic50 = 44 uM 7CG C16 H14 Br2 N2 O3 S c1cc(cc(c1....
75 4HXP - 1A5 C10 H10 N2 O3 c1cc(ccc1C....
76 6PSB ic50 = 24 uM Y18 C17 H19 N3 O2 CN1C[C@H](....
77 6CD4 ic50 = 5.14 uM EX1 C33 H42 N8 O3 CC(C)N1c2c....
78 4O7E ic50 = 5.7 uM 2RN C20 H15 N3 O c1ccc(cc1)....
79 4O74 ic50 = 0.025 uM R78 C28 H39 N7 O3 CC[C@@H]1C....
80 4BW2 ic50 = 6.31 uM UTH C24 H24 N4 O3 Cc1c(c(on1....
81 5CS8 ic50 = 2.29 uM EB8 C21 H18 N2 O5 S CCN1c2ccc(....
82 3U5J Kd = 2.46 uM 08H C17 H13 Cl N4 Cc1nnc2n1-....
83 5EIS Kd = 1.8 uM 5OU C14 H13 Cl N4 O2 CCn1cnc2c1....
84 6FO5 Kd = 0.19 uM DZH C25 H26 N6 O5 S CCn1cnc2c1....
85 6V1L Kd = 418 nM 5U6 C20 H23 N3 O3 CN1C=C(c2c....
86 3U5L Kd = 0.64 uM 08K C17 H14 Cl N5 Cc1nnc2n1-....
87 4QR4 ic50 = 0.25 uM BNK C14 H15 Cl N2 O3 S2 c1cc(c(cc1....
88 4O7A ic50 = 19 uM 2RF C16 H10 Cl2 N2 O3 c1cc(cc(c1....
89 5F61 Kd = 35 nM 5W0 C26 H34 F N7 O2 S Cc1cnc(nc1....
90 4HXN - 1A7 C9 H6 F N O S c1ccc(c(c1....
91 6DL2 Ki = 33 nM GUJ C17 H17 N3 O S Cc1c(c2c(s....
92 5Z5U - 96U C12 H10 N4 O2 c1cn(cn1)c....
93 5TI4 ic50 = 26 uM 7CM C16 H14 Cl F N2 O3 S c1cc(cc(c1....
94 5Y8C ic50 = 0.16 uM 8P9 C16 H15 Cl N2 O5 S Cc1c2cc(c(....
95 4NUD Ki < 0.0845 uM NUD C18 H17 N5 O3 S Cc1cc(c(cc....
96 4O7B ic50 = 20 uM 2RJ C26 H26 F N5 O Cc1cccc(c1....
97 5CPE ic50 = 0.45 uM EB2 C20 H24 N2 O3 S CCN1c2ccc(....
98 5MLI ic50 = 130 uM 82I C6 H8 Cl N3 O CNC1=C(C(=....
99 5DW2 Kd = 1.44 uM 5GD C24 H29 N3 O4 Cc1cc(cc(c....
100 5D3P Kd = 7.4 uM 57E C19 H21 N3 O4 S CCc1c(c([n....
101 4PCE ic50 = 7 uM 2N0 C17 H19 N O CCc1cc2c(n....
102 5D25 Kd = 0.46 uM 56M C19 H25 N3 O5 S CCN(CC)S(=....
103 5DLZ Kd = 1.8 uM 5D1 C28 H35 N3 O3 Cc1cccc(c1....
104 5Y8W ic50 = 0.23 uM 8PU C15 H13 Br N2 O5 S Cc1c2cc(c(....
105 4J0R ic50 = 0.386 uM 1H2 C18 H17 N O3 Cc1c(c(on1....
106 6MH7 ic50 = 1.3 uM JQY C26 H27 F N6 Cc1ccc(cc1....
107 5F60 Kd = 43 nM 5VZ C26 H34 Cl N7 O2 S Cc1cnc(nc1....
108 5Z5V ic50 = 287 nM 96X C15 H14 N4 O2 CC(=O)Nc1c....
109 4HXO - 1A6 C11 H10 N4 O S Cc1cc(on1)....
110 5CRM ic50 = 1.09 uM EB5 C15 H16 N2 O3 S CCNS(=O)(=....
111 6YQN ic50 = 0.72 uM P8T C32 H28 Cl N7 O2 S Cc1c(sc-2c....
112 5CQT Kd = 0.124 uM EB3 C19 H22 N2 O3 S CCN1c2ccc(....
113 5KHM Ki = 5.012 nM XNH C25 H33 N7 O3 C[C@@H]1C(....
114 6XV3 - O2B C28 H33 N9 O Cc1nnc2n1c....
115 4Z1S ic50 = 0.79 uM 559 C23 H21 Cl N6 Cc1nnc2n1-....
116 4MR3 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
117 5MKZ ic50 = 20 uM RNK C11 H12 Cl N3 O S Cc1ccsc1CN....
118 5ULA Ki = 77 nM 5MJ C20 H19 Cl N2 O3 CC1=C(CCC1....
119 4O78 ic50 = 4.6 uM SAV C21 H22 N6 O3 Cc1c2ccc(c....
120 6XVC - O32 C22 H21 N5 O2 Cc1nnc2n1c....
121 4OGJ Kd = 164 nM 2TA C27 H36 N6 O3 S Cc1cnc(nc1....
122 5A85 ic50 = 5.01 uM 78J C21 H30 N4 O2 CC1=Cc2ccn....
123 5TI6 ic50 = 21 uM 7CO C16 H14 F2 N2 O3 S c1cc(cc(c1....
124 6MAU - JBS C30 H32 N6 O3 Cc1c(c(on1....
125 6S4B Kd = 0.14 uM KUH C22 H29 N3 O5 S CCN(CC)S(=....
126 6Q3Z Kd = 44 nM HG8 C29 H38 N6 O2 S CC[C@@H]1C....
127 6V0U Kd = 392 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
128 6VUC ic50 = 144 uM RLS C16 H22 N2 O3 S CN1C[C@H](....
129 4MR4 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
130 4QR5 ic50 = 0.06 uM BNM C18 H21 N3 O4 S2 c1c(cc(cc1....
131 4MEQ - 25O C12 H11 N5 Cc1cc(n2c(....
132 4O77 ic50 = 2.5 uM 2RE C20 H14 F N3 O c1cc(ccc1c....
133 6XUZ - O1W C24 H33 N9 O2 Cc1nnc2n1c....
134 5EI4 ic50 = 26.4 uM 5NV C17 H17 Cl N8 O2 S CCn1c(nc2c....
135 5CY9 Kd = 0.218 uM E0A C17 H20 N2 O3 S CCCCS(=O)(....
136 6MH1 ic50 = 1.7 uM JQP C26 H27 F N6 Cc1cc(cc(c....
137 5CRZ ic50 = 0.45 uM EB7 C19 H14 Cl F N2 O3 S CCN1c2ccc(....
138 5Y93 ic50 = 2.27 uM 8Q9 C23 H27 Br N4 O7 S Cc1c2cc(c(....
139 5AD2 Kd = 63 nM ETU C24 H30 Cl N7 O2 C[C@@H]1C(....
140 4E96 ic50 = 0.22 uM 0NS C16 H17 N3 O4 S CN1Cc2cc(c....
141 5D0C Kd = 2.34 uM E0B C21 H25 N3 O4 S CCN1c2ccc(....
142 4O7F ic50 = 13 uM 2RQ C25 H24 F N5 O2 COc1ccccc1....
143 5CP5 Kd = 1.234 uM EB0 C19 H15 F N2 O3 S CCN1c2ccc(....
144 4CFK Kd = 1.83 uM LY2 C19 H17 N O3 c1ccc(cc1)....
145 5D3R - 57C C23 H31 N3 O4 S CCCc1c(c([....
146 4NUC Ki = 0.91 uM 435 C19 H18 N4 O3 S Cc1cc(cc(c....
147 4HXL ic50 = 2.2 uM 1A9 C22 H25 N3 O4 S3 c1cc(sc1)S....
148 6CIY ic50 = 0.41 uM F3J C34 H42 N8 O3 CN1CCN(CC1....
149 5D3L Kd = 0.88 uM 57F C21 H29 N3 O5 S CCc1c(c([n....
150 4A9L - P9L C14 H19 N3 O4 S CN1Cc2cc(c....
151 4XYA Kd = 1370 nM 43S C13 H8 Br N5 O c1coc2c1cc....
152 4C66 - H4C C17 H16 Cl N4 S CCc1cc2c(s....
153 6UWU ic50 ~ 70 nM QKP C27 H34 N2 O6 Cc1cc(cc(c....
154 4O76 ic50 = 0.13 uM 1M3 C26 H35 N7 O2 S Cc1cnc(nc1....
155 5LJ2 ic50 = 10 uM 6XW C25 H32 N6 O4 S CC1=Cc2c(c....
156 6CD5 - R4L C35 H44 N8 O3 CN1CCN(CC1....
157 5I80 Kd = 62 nM 67B C17 H17 N3 O2 CN1C=C(c2c....
158 4O75 ic50 = 21 uM 2RC C23 H26 F N6 O9 P CC1(C(=O)N....
159 5NNF - PHE LEU PRO HIS ALY TYR ASP VAL LYS LEU n/a n/a
160 3ZYU ic50 = 0.1 uM 1GH C23 H21 N5 O3 Cc1c(c(on1....
161 4Z1Q ic50 = 0.015 uM 558 C23 H21 Cl N6 Cc1nnc2n1-....
162 6SA3 Kd = 0.42 uM L2N C23 H30 N4 O5 S Cc1c2c(c([....
163 5IGK Kd = 41.8 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
164 5Y1Y ic50 = 0.98 uM HNQ C9 H6 N2 O3 c1cc2c(ccc....
165 5Z5T - 96R C12 H10 N4 O c1cc2c(cc(....
166 6V1U - QMG C20 H19 N3 O2 Cc1ccc(cc1....
167 5KDH Ki = 0.37 uM 6RX C18 H17 N3 O4 CCN1C2=C([....
168 4PS5 ic50 = 0.29 uM 2TA C27 H36 N6 O3 S Cc1cnc(nc1....
169 5D24 Kd = 5.8 uM L26 C18 H21 N3 O4 CCc1c(c([n....
170 5ACY Kd = 6.4 nM 9S3 C30 H35 N3 O C[C@H]1C[C....
171 5HCL ic50 = 6 mM 5Y9 C4 H9 N O CC(=O)N(C)....
172 5COI ic50 = 2.58 uM 55K C20 H22 N2 O5 S CCN1c2ccc(....
173 6UWX Kd = 290 uM QKD C12 H17 N O2 S2 CCOC(=O)N1....
174 5Y8Y Kd = 82 nM 8PX C16 H15 Br N2 O5 S Cc1c2cc(c(....
175 4HXM ic50 = 0.79 uM 1A8 C17 H17 N3 O4 S3 CCCC(=O)Nc....
176 5F62 Kd = 6.8 nM 5W1 C26 H33 Cl F N7 O2 S Cc1cnc(nc1....
177 5D3S Kd = 1.3 uM 579 C20 H24 F N3 O5 S CCc1c(c([n....
178 6YQP ic50 = 1.35 uM P8N C29 H27 Cl N6 O3 S Cc1c(sc-2c....
179 6AJX Kd = 9.1 uM HCC C15 H12 O4 c1cc(ccc1C....
180 4LYW Kd = 237 nM 21Q C20 H27 N3 O5 S CCc1c(c([n....
181 4HBV ic50 = 23 uM 15E C9 H9 Br N2 O CN1Cc2cc(c....
182 5LUU Kd = 8.63 uM 77X C15 H17 N3 O CCC(=O)N1C....
183 4YH3 ic50 = 26 uM Y80 C24 H20 N2 O3 COc1ccc(cc....
184 6AJV Kd = 9.1 uM HCC C15 H12 O4 c1cc(ccc1C....
185 6CZV ic50 = 0.23 uM FOY C17 H16 N2 O2 Cc1c(c(on1....
186 4X2I ic50 = 0.35 uM 3X0 C18 H17 Cl N4 Cc1nnc2n1-....
187 6CJ1 ic50 = 6.31 uM FND C34 H44 N8 O3 CC[C@H](C)....
188 5F5Z Kd = 86 nM 5VY C26 H35 N7 O2 S Cc1cnc(nc1....
189 6UVJ Kd = 20 uM QJ1 C11 H15 N O2 S2 COC(=O)N1C....
190 6FNX ic50 = 12.6 uM DYZ C14 H14 N4 O2 CCn1cnc2c1....
191 4HBY ic50 = 4.4 uM 13F C15 H15 N3 O3 S CN1Cc2cc(c....
192 5D3J Kd = 5.7 uM L33 C20 H27 N3 O4 S CCc1c(c([n....
193 6AJY Kd = 5.3 uM A0R C16 H14 O4 COc1ccccc1....
194 3MUL - GLY GLY BTK ALA PRO ARG LYS GLN n/a n/a
195 4LR6 ic50 = 33 uM 1XA C10 H10 N2 O Cc1c(c(on1....
196 5AD3 Kd = 7.9 nM K6K C26 H30 N10 O3 CN(CCOc1cc....
197 4PCI ic50 = 7.5 uM 2NJ C16 H16 N2 O CN1c2ccccc....
198 5D3T Kd = 12 uM 56Y C19 H23 N3 O3 CCc1c(c([n....
199 6SAH Kd = 0.26 uM L2W C23 H29 N3 O5 S Cc1c2c(c([....
200 5LJ1 ic50 > 0.0000316 M 6XX C28 H35 F2 N5 O3 Cc1cc(cnc1....
201 4O70 ic50 = 19 uM 1QK C21 H29 N6 O2 CCc1cnn2c1....
202 4XY9 Kd = 4651 nM 43U C12 H10 Br N5 O COc1ccc(cc....
203 3MXF - JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
204 5CFW Kd = 0.78 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
205 5A5S ic50 = 1.3 uM NP8 C20 H23 N5 O2 CC1=Cc2c(c....
206 4UIY ic50 = 0.00000001 M 5V2 C21 H20 F3 N3 O3 S2 CN1C=C(c2c....
207 6PS9 ic50 = 79 uM Y17 C18 H21 N3 O2 CN1C[C@@H]....
208 4LZR Kd = 20 uM LOC C22 H25 N O6 CC(=O)N[C@....
209 6PRT ic50 = 2120 uM OWA C8 H13 N O3 CN1C[C@H](....
210 4BW1 ic50 = 1.26 uM S5B C25 H25 N3 O3 Cc1c(c(on1....
211 6YQO ic50 = 4.53 uM P8Q C33 H36 Cl N7 O4 S Cc1c(sc-2c....
212 4MEN - 25K C15 H17 N5 Cc1ccc(cc1....
213 6CIS ic50 = 0.3 uM X26 C37 H48 N8 O3 CC(C)Oc1cc....
214 6CKR ic50 = 0.05 uM F5V C21 H20 N4 O3 S Cn1cc(cn1)....
215 4UIZ ic50 = 0.00001995 M N1D C22 H25 N3 O6 S2 CN1C=C(c2c....
216 5KJ0 ic50 = 130 nM 6TB C29 H41 N7 O3 CC[C@@H]1C....
217 4KV1 - THR PHE ALY SER ILE MET LYS n/a n/a
218 5EGU Kd = 1.4 uM 5NQ C23 H32 N8 O2 S CCCCc1c(nc....
219 5Y8Z ic50 = 0.62 uM 8Q3 C16 H15 Br N2 O4 S Cc1cc2c(cc....
220 6VUB ic50 = 629 uM RLG C11 H13 N O CN1C[C@H](....
221 4BW3 ic50 = 501 nM 9BM C25 H26 N4 O4 Cc1c(c(on1....
222 3U5K - 08J C18 H13 Cl F N3 Cc1ncc2n1-....
223 6FGH - 6RZ C10 H16 N2 O2 S Cc1c(cccn1....
224 6FG6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
225 6FGG Kd = 17 uM D9B C18 H20 N4 O4 CN1C=C(C=C....
226 5MGJ Kd = 51 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
227 6FGV - D9T C14 H21 N3 O2 CN1C=C(C=C....
228 6FGL ic50 = 24 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
229 5OR8 - JR4 C17 H18 F N3 O3 S Cc1cc2c(cc....
230 5FE0 - ALY C8 H16 N2 O3 CC(=O)NCCC....
231 5LVR Kd = 250 uM 78Y C10 H10 N4 O Cc1c(nn(n1....
232 5FDZ Kd = 6.8 uM 5X0 C21 H24 N2 O5 CNC(=O)c1c....
233 5FE1 - 12Q C10 H9 N O CN1c2ccccc....
234 5FE6 Kd = 6910 uM 5WZ C9 H16 N2 O C1CC1C(=O)....
235 5FE2 - 5WV C9 H9 N O CN1Cc2cccc....
236 5FE7 Kd = 488 uM 5WU C10 H14 N2 O2 Cc1c2c(n(n....
237 5FE8 - 5WT C13 H14 N2 O2 CC1=CC(=O)....
238 5FE4 - 5WY C9 H9 N O3 c1cc(c2c(c....
239 5FE9 Kd = 20.98 uM 5WS C12 H14 N2 O3 S CC1=CC(=O)....
240 5FE5 - 2QC C9 H9 N3 S c1cc(ccc1C....
241 5MKX ic50 = 20 uM 82I C6 H8 Cl N3 O CNC1=C(C(=....
242 5LVQ Kd = 73 uM 2LX C13 H17 N O3 CNC(=O)c1c....
243 5FE3 - 5WX C8 H8 N2 O2 COc1cccc2c....
244 6C7Q - EO1 C25 H23 N7 O2 Cc1c(c(on1....
245 2YEM ic50 = 15.5 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
246 5JWM ic50 = 3.09 nM 6ON C54 H66 Cl2 N10 O9 S2 Cc1c(sc-2c....
247 5UOO Ki = 1.4 nM 8FV C26 H21 N5 O2 Cc1c(c(on1....
248 3QZS Kd = 99 uM LYS GLY GLY ALA ALY ARG HIS ARG LYS VAL n/a n/a
249 3QZT - LYS GLY GLY ALA ALY ARG HIS ARG LYS VAL n/a n/a
250 5U6V ic50 = 21 nM 7WY C22 H19 Cl N6 Cc1c-2n(nn....
251 5O3A - 31P C23 H23 Cl N4 O3 CC[C@H]([C....
252 5DFD - 59E C23 H21 N5 O3 Cc1nnc2n1-....
253 5XHK - LDR C13 H9 N O c1ccc2c(c1....
254 5O3D - 9J5 C23 H23 Cl N4 O3 CC[C@H]([C....
255 6YTM Kd = 65 nM PMW C22 H25 Cl N4 O2 S CC[C@H]([C....
256 6VIY Ki = 1.1 nM QYY C27 H29 N3 O5 S CCNC(=O)c1....
257 5IG6 Kd = 213.7 uM 6B3 C27 H18 N2 O4 c1ccc2c(c1....
258 5O3G - 9J8 C25 H26 Cl N5 O2 CCNC(=O)[C....
259 4J1P Kd = 0.206 uM 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
260 5O3I - 9HN C27 H29 Cl N4 O3 Cc1nnc2n1-....
261 5UEW - 87D C20 H20 N2 O5 S CN1C=C(C(=....
262 5O3B - 9HZ C24 H23 Cl N4 O3 Cc1nnc2n1-....
263 5O3E - 9HW C23 H24 Cl N5 O2 CCNC(=O)[C....
264 3ONI - JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
265 6K04 Ki = 3.1 nM CQF C22 H21 Cl N6 Cc1nnc2n1-....
266 5O39 - 31O C22 H21 Cl N4 O3 Cc1nnc2n1-....
267 5O3H - 9HQ C23 H24 Cl N5 O2 CCNC(=O)[C....
268 5O3C - 9J2 C22 H21 Cl N4 O3 Cc1nnc2n1-....
269 4MR6 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
270 6MOA Kd = 2.5 nM JW4 C25 H22 N4 O Cc1ccc2c(c....
271 5DW1 ic50 = 0.08 uM 5GD C24 H29 N3 O4 Cc1cc(cc(c....
272 5DFC - EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
273 4MR5 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
274 5O3F - 9HT C24 H26 Cl N5 O2 CC[C@H]([C....
275 2WP1 - LYS ALA PRO ARG ALY GLN LEU ALA THR LYS n/a n/a
276 4FLP Kd = 190.1 nM JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
277 4KCX Kd = 37 uM 1QK C21 H29 N6 O2 CCc1cnn2c1....
278 4A9I - P9I C15 H13 N2 O C/C(=C/1C=....
279 4UYH ic50 = 0.00000001 M 9S3 C30 H35 N3 O C[C@H]1C[C....
280 4A9H - TVP C12 H15 N O C[C@H]1CCc....
281 4A9F - MB3 C5 H9 N O CN1CCCC1=O
282 4ALG ic50 = 0.5 uM 1GH C23 H21 N5 O3 Cc1c(c(on1....
283 2YEK ic50 = 32.5 nM EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
284 2YDW Kd = 46 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
285 4A9J - TYL C8 H9 N O2 CC(=O)Nc1c....
286 4A9M ic50 = 0.5 uM P9M C17 H22 N2 O3 S Cc1ccc(cc1....
287 4ALH - A9P C11 H11 N O Cc1c(c(on1....
288 4A9E - 3PF C9 H10 N2 O CN1Cc2cccc....
289 4A9O - A9O C12 H13 N O CCc1c(c(no....
290 4AKN ic50 = 0.79 uM S5B C25 H25 N3 O3 Cc1c(c(on1....
291 4A9N ic50 = 1.5 uM A9N C15 H16 N2 O3 S Cc1ccc(cc1....
292 4KV4 - THR PHE ALY SER ILE MET LYS n/a n/a
293 5UEZ Ki = 970 nM 89G C18 H16 N2 O3 CN1C(=O)C=....
294 6VIX Ki = 1.3 nM QYV C24 H21 F2 N3 O5 S CCNC(=O)c1....
295 5UF0 Ki = 160 uM 89J C12 H13 N3 O CNC1=CC(=O....
296 5UEU - 0S6 C20 H19 Cl N4 O2 S Cc1c(sc-2c....
297 4Z93 Kd = 44.6 nM 4LD C24 H23 N5 O2 Cc1c(c(n[n....
298 5UEY Ki = 5.1 nM 88M C22 H24 F2 N2 O5 S CCOC1=CC(=....
299 5UEX Ki = 1.5 nM 89D C24 H26 F2 N2 O5 S CCS(Nc1ccc....
300 5I8B ic50 = 0.11 uM 69F C23 H22 N2 O2 C[C@@H]1CC....
301 5I8G Kd = 0.03 uM 69E C22 H22 N6 O C[C@@H]1CC....
302 5N18 Kd = 2.1 uM 8HZ C21 H19 N3 O Cc1ccc(cc1....
303 5MLJ Ki = 1.4 nM 9ST C17 H21 Br N4 O CN1C[C@H](....
304 6J3P Kd = 105 nM B8O C21 H25 N5 O3 CN1C[C@H](....
305 6AXQ ic50 = 99000 nM C2Y C10 H9 N O2 COC(=O)c1c....
306 5DBM Kd = 0.35 uM 58N C17 H22 N4 O C[C@@H]1CC....
307 5LPM Kd = 2.77 uM 71Y C20 H23 Cl N2 O3 CCc1c(c([n....
308 5NRW - 96N C21 H22 N2 O2 CCc1c(c([n....
309 3P1D - MB3 C5 H9 N O CN1CCCC1=O
310 5LPJ Kd = 10.1 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
311 6FQO ic50 = 0.14 uM E2T C26 H24 N2 O6 CCOc1ccc(c....
312 4TQN Kd = 0.77 uM UL4 C18 H17 N O5 CCOc1ccc(c....
313 6FRF ic50 = 0.04 uM E3T C26 H24 N2 O5 CCOc1ccc(c....
314 5TB6 Kd = 1.53 uM 77X C15 H17 N3 O CCC(=O)N1C....
315 5MQK - QPR C11 H11 N O CC(=O)c1cn....
316 5MQG - F31 C9 H11 N O2 CC(=O)c1cc....
317 5I83 ic50 = 4.1 uM 68Y C18 H20 N2 O2 C[C@@H]1CC....
318 4A9K - TYL C8 H9 N O2 CC(=O)Nc1c....
319 5I86 ic50 = 0.53 uM 69A C18 H19 N3 O2 C[C@@H]1CC....
320 6FR0 ic50 = 0.146 uM E3H C27 H26 N2 O6 CCN1C(=O)C....
321 5NU5 Kd = 0.47 uM 99E C21 H22 N2 O4 CCc1c(c([n....
322 5LPK Kd = 3.06 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
323 5MME Kd = 1.4 uM 8Q6 C20 H21 N O6 CCOc1ccc(c....
324 5I89 ic50 = 0.033 uM 69B C21 H22 N4 O C[C@@H]1CC....
325 5NU3 Kd = 0.23 uM 99E C21 H22 N2 O4 CCc1c(c([n....
326 5OWK - 7MX C9 H10 Cl N O3 CCOC(=O)C1....
327 6AY5 ic50 = 69 nM C3V C22 H20 F2 N4 O S Cn1cc(cn1)....
328 5LPL Kd = 12 uM 71X C20 H23 Cl N2 O3 CCc1c(c([n....
329 6FQU ic50 = 2.2 uM E3B C21 H23 F2 N O2 CCOc1ccc(c....
330 6DMK - 2LL C26 H30 N4 O2 Cc1c(c(on1....
331 5MMG Kd = 0.97 uM UT0 C19 H20 N2 O4 S CCOc1ccc(c....
332 5MPN Kd = 0.085 uM YE5 C17 H16 N4 O2 CCOc1ccc(c....
333 5J0D Kd = 134 nM 6F9 C27 H35 N3 O5 CCC(=O)N1C....
334 6AY3 ic50 = 9.5 nM C3J C24 H23 F2 N5 O CNC(=O)c1c....
335 5MPK Kd = 0.003 uM 0BC C21 H18 N6 O3 S CCOc1ccc(c....
336 5CGP Kd = 0.12 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
337 4BJX ic50 = 22 nM 73B C25 H23 Cl N2 O3 C[C@H]1C[C....
338 4UYD ic50 = 79.4 uM V1T C10 H11 N3 O2 CN1c2ccc(c....
339 4XUB ic50 = 1.07 uM 43D C19 H18 N8 Cc1cn(nn1)....
340 4XUA ic50 = 26 uM 43C C21 H18 N6 Cc1cn(nn1)....
341 5MGF Kd = 54 uM 7MW C9 H11 N O3 CCC(=O)c1c....
342 5E9I - F60 C8 H7 N O c1cc(cc2c1....
343 6FGT - D9T C14 H21 N3 O2 CN1C=C(C=C....
344 4NRB ic50 = 38 uM 2LX C13 H17 N O3 CNC(=O)c1c....
345 6FH6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
346 5MGG - 7MU C7 H7 Cl N2 O CNC(=O)c1c....
347 5ORB - JR6 C16 H19 N3 O2 S Cn1c(c2c(n....
348 4NRC ic50 = 241 uM 2LY C8 H9 N O3 S CNC(=O)c1c....
349 6FH7 - EN2 C17 H18 F N3 O3 CN1C=C(C=C....
350 5E9K - 5KX C3 H3 Cl N2 c1cnc([nH]....
351 4NRA Kd = 65 uM 2LW C13 H13 Cl N2 O CC(=O)N1CC....
352 5MGE Kd = 87 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
353 4NR9 - ALY C8 H16 N2 O3 CC(=O)NCCC....
354 5E9L - 6AI C7 H7 N3 c1cc2cn[nH....
355 5OR9 ic50 = 88 uM JR5 C18 H21 F N4 O3 S Cn1c(c2c(n....
356 5E74 Kd = 39 uM 5KH C25 H19 F3 N2 O3 Cc1ccc(cc1....
357 5E9M - BAE C6 H13 N O CC(C)(C)C(....
358 6FGU - D9Q C13 H19 N3 O2 CN1C=C(C=C....
359 5DYX - ADE C5 H5 N5 c1[nH]c2c(....
360 5DYU - MZ0 C4 H6 N2 O c1c([nH]cn....
361 5E73 Kd = 23 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
362 7K6R - 9ST C17 H21 Br N4 O CN1C[C@H](....
363 7KDW - WCV C20 H21 N5 O C#CCNc1ncc....
364 7KDZ - WCS C22 H30 N6 O3 S CN(C)CCCOc....
365 7K6S - VYM C13 H16 N2 O c1cc2c(cc1....
366 5A7C ic50 = 0.00018 M 5D4 C10 H20 N2 O2 CC(=O)NCCC....
367 5TPX Kd = 280 nM 7H7 C21 H24 N6 Cc1nnc2n1n....
368 6MO8 - JWD C19 H17 N3 O2 Cc1c(c(on1....
369 6ONY - HWV C28 H30 F N3 O4 CCNC(=O)c1....
370 6JKE - BUX C13 H6 Cl2 N2 O4 c1cc(cc(c1....
371 6MO7 - JWA C19 H25 N3 O4 S Cc1ccc(cc1....
372 6MO9 - JVY C19 H21 N3 O3 S Cc1c(c(on1....
373 3AQA - BYH C17 H16 N4 S2 CN1c2ccccc....
374 6K05 Ki = 95.5 nM CQF C22 H21 Cl N6 Cc1nnc2n1-....
375 5WUU ic50 = 0.81 uM 7UU C18 H18 N2 O3 S CN(CCCNC1=....
376 5N17 Kd = 4.8 uM 8FK C19 H18 N2 O3 S CN1c2ccc(c....
377 5N16 Kd = 5 uM 8FN C22 H15 N5 O2 S c1ccc2c(c1....
378 6VIZ Ki = 120 nM QYY C27 H29 N3 O5 S CCNC(=O)c1....
379 6VIW Ki = 21.6 nM QYV C24 H21 F2 N3 O5 S CCNC(=O)c1....
380 5XXH ic50 = 6.8 uM E0D C18 H20 N2 O4 CC(=O)c1cn....
381 5ML0 - P2L C11 H17 Cl N4 O CN1CCC[C@H....
382 5W0L ic50 = 1.1 nM 9UD C27 H32 F2 N6 O2 CC(=O)N1CC....
383 5W0F ic50 = 16 nM 9U7 C25 H30 N6 O2 CC(=O)N1CC....
384 5W0E ic50 = 0.94 nM 9U4 C27 H33 F2 N7 O2 CNC(=O)N1C....
385 5W0Q ic50 = 18 uM 9UG C12 H16 N2 O2 Cc1ccc2c(c....
386 5W0I ic50 = 1.4 nM 9UA C26 H30 F2 N6 O2 CC(=O)N1CC....
387 5VOM ic50 = 0.79 uM 9GY C24 H23 N3 O4 C[C@H]1CN(....
388 2RI7 - ALA ARG THR MLY GLN THR ALA ARG LYS n/a n/a
389 6J3O Kd = 2.4 uM B4L C13 H19 N5 O CN1CCC[C@H....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: F60; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 F60 1 1
2 1F1 0.454545 0.703704
3 5H1 0.439024 0.916667
4 3ID 0.404762 0.827586
Similar Ligands (3D)
Ligand no: 1; Ligand: F60; Similar ligands found: 1263
No: Ligand Similarity coefficient
1 14O 1.0000
2 5MI 1.0000
3 5MB 1.0000
4 2K4 1.0000
5 6AI 1.0000
6 BZX 1.0000
7 11S 0.9993
8 ES9 0.9990
9 FK1 0.9947
10 JAE 0.9945
11 H4N 0.9944
12 COU 0.9882
13 8NY 0.9867
14 H42 0.9867
15 4FS 0.9862
16 JB5 0.9848
17 03V 0.9844
18 2AQ 0.9837
19 NPO 0.9834
20 ES5 0.9818
21 OCH 0.9811
22 5OB 0.9806
23 ET2 0.9787
24 ABV 0.9770
25 BZ3 0.9764
26 36R 0.9754
27 QUZ 0.9750
28 PHB 0.9747
29 5WV 0.9745
30 DEN 0.9743
31 CLW 0.9736
32 ES2 0.9733
33 6M9 0.9731
34 RM1 0.9729
35 ISN 0.9722
36 AX7 0.9721
37 OAA 0.9720
38 1P8 0.9716
39 XQ0 0.9715
40 9DG 0.9713
41 MR1 0.9711
42 NPY 0.9708
43 IND 0.9705
44 8GC 0.9705
45 1P7 0.9703
46 5XC 0.9700
47 6GU 0.9699
48 67N 0.9694
49 AZA 0.9692
50 VGD 0.9692
51 0CT 0.9692
52 7W4 0.9688
53 GUN 0.9687
54 BZI 0.9686
55 DMD 0.9685
56 5VM 0.9684
57 TH7 0.9682
58 4JP 0.9682
59 M1A 0.9680
60 0RW 0.9678
61 BEZ 0.9678
62 1PT 0.9678
63 A2F 0.9677
64 270 0.9676
65 F05 0.9676
66 PAB 0.9676
67 6AP 0.9674
68 XAN 0.9673
69 9EW 0.9671
70 BZF 0.9669
71 5B1 0.9667
72 YCP 0.9667
73 AZG 0.9666
74 AHR 0.9665
75 RSF 0.9665
76 P92 0.9659
77 BAM 0.9658
78 LZ1 0.9657
79 141 0.9657
80 6PC 0.9654
81 BEN 0.9652
82 1DW 0.9648
83 F9Y 0.9643
84 XYP 0.9641
85 HLR 0.9639
86 HMH 0.9638
87 0R1 0.9637
88 DX4 0.9636
89 NCA 0.9636
90 IGA 0.9635
91 HBD 0.9633
92 KKN 0.9632
93 QWN 0.9630
94 1Y6 0.9630
95 2MI 0.9626
96 MPI 0.9626
97 GVH 0.9626
98 6M4 0.9623
99 1XM 0.9622
100 FBB 0.9622
101 IDM 0.9621
102 I3A 0.9620
103 4CS 0.9620
104 SAL 0.9619
105 K2T 0.9618
106 LXC 0.9614
107 HH5 0.9612
108 SVN 0.9611
109 4JT 0.9610
110 0CU 0.9610
111 ES7 0.9609
112 TH0 0.9609
113 3HB 0.9608
114 YH7 0.9607
115 7HQ 0.9605
116 JBE 0.9602
117 GLC 0.9598
118 ISZ 0.9596
119 NBZ 0.9596
120 XM0 0.9595
121 MCT 0.9594
122 FYU 0.9592
123 AZ8 0.9592
124 3AB 0.9592
125 2CK 0.9587
126 NIO 0.9582
127 CFP 0.9581
128 GAB 0.9581
129 4SV 0.9576
130 290 0.9571
131 QXW 0.9570
132 3F0 0.9570
133 NTN 0.9568
134 HBA 0.9568
135 MLT 0.9568
136 173 0.9564
137 5HN 0.9563
138 5CU 0.9563
139 BOA 0.9563
140 BE2 0.9559
141 NOJ 0.9559
142 PE0 0.9557
143 5RG 0.9557
144 FA0 0.9552
145 2HQ 0.9552
146 5NU 0.9551
147 4M0 0.9549
148 URF 0.9548
149 53C 0.9544
150 3NT 0.9542
151 BGC 0.9542
152 717 0.9541
153 8H8 0.9540
154 3HA 0.9538
155 4HO 0.9536
156 J9W 0.9535
157 ES6 0.9533
158 PBZ 0.9531
159 PZA 0.9529
160 BHO 0.9528
161 DBH 0.9528
162 MEW 0.9528
163 3PF 0.9528
164 3U4 0.9526
165 5QY 0.9521
166 URC 0.9520
167 BCP 0.9519
168 XBT 0.9518
169 VGL 0.9517
170 Q24 0.9515
171 TDR 0.9515
172 DOB 0.9514
173 NK 0.9513
174 14J 0.9511
175 2BG 0.9510
176 AC0 0.9510
177 4XR 0.9508
178 JBK 0.9507
179 Z82 0.9507
180 UNU 0.9506
181 1MC 0.9506
182 SYV 0.9505
183 LZM 0.9505
184 174 0.9505
185 3M0 0.9504
186 4MA 0.9502
187 42A 0.9499
188 KJH 0.9499
189 FQI 0.9498
190 KOJ 0.9497
191 WCE 0.9494
192 OVV 0.9493
193 5JQ 0.9493
194 TTL 0.9493
195 G3E 0.9491
196 WBU 0.9491
197 JZ9 0.9490
198 EA1 0.9490
199 MWM 0.9490
200 HMU 0.9489
201 5JC 0.9489
202 4JU 0.9489
203 MZG 0.9487
204 4HC 0.9486
205 86J 0.9483
206 826 0.9483
207 FE DB1 0.9482
208 12Q 0.9482
209 5UC 0.9482
210 HQT 0.9481
211 8ZE 0.9480
212 54D 0.9478
213 BHA 0.9475
214 NIZ 0.9475
215 CTL 0.9475
216 Q88 0.9474
217 KUF 0.9472
218 PBC 0.9471
219 BE7 0.9469
220 CWS 0.9469
221 M5K 0.9468
222 24B 0.9466
223 GTQ 0.9465
224 7W1 0.9465
225 XBZ 0.9465
226 4VP 0.9463
227 5MH 0.9463
228 HIS 0.9460
229 SS1 0.9460
230 AQO 0.9459
231 P72 0.9459
232 BTY 0.9456
233 5Q0 0.9456
234 AJ2 0.9455
235 DHB 0.9455
236 1SQ 0.9454
237 XIY 0.9453
238 FDB 0.9452
239 4ZE 0.9451
240 3BZ 0.9450
241 4YS 0.9449
242 XAZ 0.9449
243 HPA 0.9447
244 N5J 0.9445
245 4CL 0.9443
246 0R0 0.9442
247 5SG 0.9441
248 5QX 0.9441
249 NSP 0.9441
250 D48 0.9439
251 I1E 0.9437
252 5IQ 0.9437
253 1NP 0.9437
254 ADE 0.9437
255 MWJ 0.9437
256 23A 0.9435
257 CFI 0.9434
258 1LQ 0.9433
259 75K 0.9431
260 HQY 0.9431
261 JZ3 0.9431
262 PXL 0.9430
263 B55 0.9429
264 0P6 0.9429
265 27Y 0.9428
266 2CQ 0.9428
267 M1Q 0.9428
268 A7W 0.9427
269 7B4 0.9426
270 E5X 0.9424
271 4JJ 0.9421
272 O72 0.9420
273 BRT 0.9419
274 4NC 0.9417
275 2MH 0.9416
276 54G 0.9414
277 3OC 0.9414
278 ES0 0.9413
279 CWM 0.9413
280 10L 0.9412
281 JPZ 0.9411
282 4P5 0.9409
283 KJU 0.9408
284 4HM 0.9408
285 UGC 0.9407
286 ES1 0.9405
287 1WG 0.9404
288 PRO 0.9402
289 ICP 0.9401
290 OXQ 0.9400
291 6MP 0.9399
292 2YU 0.9398
293 JKE 0.9397
294 B53 0.9397
295 5M0 0.9395
296 2AC 0.9395
297 BR9 0.9395
298 6NT 0.9392
299 TP5 0.9392
300 1M2 0.9391
301 6CS 0.9391
302 ZBT 0.9391
303 ADZ 0.9389
304 275 0.9389
305 8TX 0.9389
306 24W 0.9388
307 LG4 0.9388
308 G3F 0.9388
309 8CM 0.9387
310 HQE 0.9387
311 J5I 0.9386
312 J1Z 0.9386
313 5RN 0.9384
314 MQN 0.9383
315 9MG 0.9383
316 SKA 0.9382
317 4JQ 0.9381
318 QBK 0.9381
319 M6N 0.9380
320 ZZT 0.9380
321 OVM 0.9379
322 2ZM 0.9379
323 3NY 0.9379
324 150 0.9378
325 PLQ 0.9377
326 7WA 0.9376
327 SE2 0.9376
328 1WD 0.9375
329 1LM 0.9372
330 DIN 0.9370
331 HHA 0.9370
332 FOA 0.9370
333 N2I 0.9369
334 TIU 0.9369
335 43M 0.9367
336 ES4 0.9366
337 TPA 0.9366
338 7WV 0.9365
339 3MB 0.9363
340 DYA 0.9363
341 A1U 0.9361
342 HT4 0.9361
343 5JL 0.9360
344 FAN 0.9358
345 JBH 0.9358
346 P9P 0.9354
347 PCR 0.9354
348 6RQ 0.9353
349 MRW 0.9353
350 BP1 0.9353
351 0TU 0.9352
352 4XH 0.9352
353 XYD 0.9351
354 RHU 0.9351
355 0JD 0.9351
356 2EC 0.9351
357 60P 0.9350
358 CWJ 0.9349
359 0TR 0.9348
360 XYS 0.9348
361 GCS 0.9348
362 JA8 0.9346
363 5NI 0.9346
364 DA1 0.9345
365 34A 0.9344
366 JZ2 0.9343
367 HY3 0.9343
368 4YO 0.9342
369 9HX 0.9342
370 CRS 0.9342
371 4JO 0.9341
372 H8N 0.9341
373 4ZC 0.9341
374 FPY 0.9341
375 XX2 0.9340
376 OK7 0.9340
377 SWD 0.9340
378 M1E 0.9339
379 9DA 0.9337
380 INO 0.9337
381 AC6 0.9337
382 LT2 0.9336
383 4A3 0.9335
384 PXY 0.9335
385 MYJ 0.9334
386 0HN 0.9333
387 FPN 0.9333
388 XQG 0.9332
389 25R 0.9332
390 URP 0.9332
391 LMR 0.9330
392 PYD 0.9329
393 SX1 0.9327
394 GAG 0.9327
395 51R 0.9327
396 BTE 0.9327
397 KDV 0.9322
398 F9P 0.9321
399 PNZ 0.9320
400 M58 0.9319
401 HH8 0.9318
402 7CZ 0.9318
403 GBD 0.9317
404 2MP 0.9316
405 5MK 0.9315
406 2D0 0.9315
407 3DM 0.9313
408 JLZ 0.9313
409 G6D 0.9313
410 IUR 0.9311
411 82I 0.9311
412 PYC 0.9311
413 93K 0.9310
414 2HU 0.9310
415 45C 0.9310
416 1DU 0.9310
417 NNO 0.9309
418 FBM 0.9308
419 QSC 0.9308
420 TM7 0.9308
421 IDH 0.9307
422 BSX 0.9306
423 PM6 0.9304
424 7HP 0.9303
425 RSO 0.9303
426 AMC 0.9300
427 IT2 0.9299
428 3HM 0.9298
429 4HS 0.9296
430 PZI 0.9296
431 FP1 0.9293
432 1P3 0.9292
433 6NI 0.9291
434 2PC 0.9290
435 FHB 0.9289
436 3SK 0.9289
437 B57 0.9288
438 F81 0.9288
439 ICO 0.9288
440 IFL 0.9288
441 IV2 0.9287
442 RCO 0.9287
443 M2K 0.9287
444 1DV 0.9286
445 PCA 0.9286
446 3XX 0.9286
447 PY7 0.9286
448 0HO 0.9284
449 5GU 0.9283
450 C21 0.9283
451 4AA 0.9282
452 SOE 0.9282
453 2HO 0.9281
454 261 0.9281
455 FBA 0.9278
456 282 0.9278
457 8S0 0.9276
458 8IG 0.9271
459 R8V 0.9271
460 ASO 0.9270
461 PKU 0.9270
462 FUL 0.9268
463 5AC 0.9267
464 R8S 0.9267
465 ABI 0.9266
466 VNJ 0.9266
467 FPI 0.9266
468 BML 0.9265
469 8OZ 0.9264
470 EQT 0.9263
471 JAW 0.9262
472 9TZ 0.9262
473 4BZ 0.9260
474 DHR 0.9258
475 SHA 0.9254
476 94W 0.9251
477 SYN 0.9251
478 284 0.9251
479 BCU 0.9250
480 3CH 0.9250
481 4WL 0.9249
482 3A9 0.9248
483 HBX 0.9248
484 TZC 0.9248
485 E7Z 0.9247
486 SW7 0.9245
487 3Z8 0.9245
488 4JM 0.9243
489 RIP 0.9243
490 J9T 0.9242
491 FCR 0.9241
492 KT7 0.9240
493 NDH 0.9240
494 MZW 0.9239
495 PEA 0.9239
496 AKG 0.9238
497 QOS 0.9236
498 AZ9 0.9236
499 4CH 0.9235
500 J9Q 0.9232
501 0W8 0.9231
502 PHU 0.9230
503 OW4 0.9230
504 8WO 0.9230
505 ANN 0.9229
506 B62 0.9229
507 P3K 0.9228
508 25W 0.9228
509 QSB 0.9227
510 Y8I 0.9227
511 QX2 0.9225
512 7WG 0.9223
513 URA 0.9223
514 GRE 0.9222
515 4JL 0.9222
516 M0W 0.9219
517 F4Z 0.9218
518 4JN 0.9217
519 TSU 0.9216
520 C2B 0.9216
521 DBX 0.9215
522 273 0.9215
523 QWW 0.9214
524 0MK 0.9214
525 GYE 0.9214
526 4FA 0.9214
527 MAE 0.9213
528 MUA 0.9212
529 ABN 0.9212
530 LG3 0.9212
531 CYT 0.9211
532 6M1 0.9211
533 7VS 0.9210
534 CHB 0.9209
535 HX3 0.9207
536 PYF 0.9206
537 PYG 0.9206
538 2ZV 0.9205
539 TC7 0.9205
540 EUG 0.9204
541 ASP 0.9204
542 DRL 0.9203
543 K34 0.9202
544 ODO 0.9201
545 WOT 0.9200
546 265 0.9200
547 G2F 0.9200
548 ARB 0.9200
549 9R5 0.9199
550 9TW 0.9198
551 L3Q 0.9198
552 BPN 0.9198
553 HDH 0.9197
554 NMJ 0.9196
555 TSS 0.9196
556 7MU 0.9195
557 DFB 0.9192
558 TLD 0.9191
559 286 0.9190
560 BVF 0.9188
561 GAL 0.9187
562 HGQ 0.9185
563 EKZ 0.9185
564 3Z7 0.9185
565 7NI 0.9183
566 DE5 0.9181
567 JBN 0.9181
568 SMV 0.9181
569 2A9 0.9180
570 3FH 0.9180
571 2LP 0.9178
572 MWP 0.9177
573 XRG 0.9177
574 SAN 0.9175
575 6F0 0.9174
576 LG5 0.9173
577 3ZQ 0.9173
578 SRT 0.9172
579 G5V 0.9171
580 FUC 0.9169
581 32X 0.9167
582 9FL 0.9167
583 RMN 0.9165
584 1XN 0.9163
585 OHG 0.9162
586 0FO 0.9161
587 JDN 0.9160
588 92K 0.9160
589 JAB 0.9160
590 DTL 0.9160
591 IHB 0.9159
592 R8A 0.9158
593 PBA 0.9157
594 M2H 0.9154
595 TGX 0.9148
596 XHP 0.9147
597 26D 0.9147
598 B3R 0.9145
599 AEF 0.9144
600 IOL 0.9143
601 MNM 0.9142
602 TLA 0.9142
603 QX4 0.9140
604 OTW 0.9138
605 HEW 0.9138
606 DFU 0.9136
607 3DO 0.9135
608 JB8 0.9135
609 R9S 0.9134
610 UY7 0.9132
611 IPB 0.9130
612 NQ 0.9128
613 HLZ 0.9126
614 DHQ 0.9126
615 BEA 0.9125
616 NOY 0.9125
617 YRL 0.9124
618 TEO 0.9124
619 DQU 0.9123
620 DGJ 0.9123
621 4ZA 0.9121
622 44W 0.9121
623 GOJ 0.9121
624 OTR 0.9120
625 IFP 0.9117
626 OXC 0.9117
627 MBD 0.9117
628 15E 0.9117
629 BDP 0.9117
630 JIF 0.9116
631 M3T 0.9116
632 2AK 0.9115
633 UNC 0.9115
634 F0J 0.9113
635 AGK 0.9113
636 GLA 0.9113
637 HQD 0.9111
638 3WA 0.9111
639 AAS 0.9111
640 8WT 0.9111
641 RXA 0.9107
642 MO8 0.9105
643 XUL 0.9103
644 IFM 0.9103
645 5RO 0.9101
646 97T 0.9101
647 N8Y 0.9100
648 259 0.9100
649 4H2 0.9100
650 3FA 0.9100
651 2AL 0.9099
652 Q6T 0.9098
653 23W 0.9098
654 T6C 0.9096
655 F5B 0.9095
656 MS9 0.9094
657 NBE 0.9093
658 FBV 0.9091
659 VNL 0.9091
660 42C 0.9089
661 TFB 0.9088
662 PZM 0.9085
663 VK3 0.9083
664 ORO 0.9083
665 RAM 0.9082
666 KJY 0.9080
667 7N0 0.9080
668 FB1 0.9080
669 L99 0.9080
670 2H5 0.9080
671 4Z4 0.9079
672 CIG 0.9078
673 RIB 0.9078
674 DUC 0.9078
675 C2A 0.9077
676 AZF 0.9076
677 SJ5 0.9075
678 CTS 0.9075
679 1DQ 0.9075
680 RB5 0.9074
681 V55 0.9073
682 MAK 0.9073
683 FB2 0.9073
684 GXY 0.9072
685 M4T 0.9071
686 6VD 0.9069
687 LGC 0.9069
688 8GF 0.9064
689 GIF 0.9064
690 JZ1 0.9064
691 M1H 0.9064
692 XCZ 0.9062
693 TEP 0.9062
694 3CE 0.9062
695 GIO 0.9062
696 FBW 0.9060
697 GLU 0.9060
698 GMN 0.9059
699 KYD 0.9059
700 HHQ 0.9057
701 CAQ 0.9057
702 MT0 0.9056
703 GCU 0.9056
704 15N 0.9053
705 6MH 0.9052
706 AJV 0.9051
707 0N7 0.9051
708 F31 0.9051
709 4M4 0.9051
710 1MR 0.9050
711 4NM 0.9050
712 2C9 0.9050
713 PAC 0.9046
714 PDC 0.9046
715 CXF 0.9046
716 LDU 0.9046
717 HSM 0.9045
718 ECE 0.9043
719 37T 0.9042
720 A29 0.9039
721 3MC 0.9039
722 MVN 0.9039
723 R9Y 0.9039
724 XXR 0.9038
725 4MU 0.9037
726 B60 0.9037
727 TM4 0.9037
728 DIE 0.9036
729 3RK 0.9036
730 2DR 0.9036
731 9CA 0.9035
732 DBJ 0.9034
733 HYP 0.9034
734 2CH 0.9033
735 ABE 0.9031
736 X0V 0.9031
737 HSO 0.9028
738 LDP 0.9028
739 SWA 0.9027
740 GUA 0.9027
741 BP9 0.9026
742 1SA 0.9025
743 OXE 0.9025
744 HA5 0.9025
745 2FY 0.9023
746 EYK 0.9022
747 HJP 0.9022
748 AKH 0.9021
749 TMZ 0.9021
750 GLL 0.9021
751 HIO 0.9020
752 MXN 0.9019
753 J6W 0.9019
754 BZ2 0.9018
755 FLM 0.9017
756 HY1 0.9016
757 PRZ 0.9016
758 6ME 0.9016
759 FFP 0.9015
760 40O 0.9015
761 FBS 0.9013
762 TTY 0.9013
763 MNN 0.9012
764 2CM 0.9012
765 069 0.9012
766 PQ0 0.9012
767 H76 0.9012
768 47J 0.9011
769 HQJ 0.9011
770 MLA 0.9011
771 44V 0.9009
772 2MY 0.9008
773 2A7 0.9007
774 ESP 0.9006
775 1DJ 0.9005
776 FOT 0.9005
777 OXZ 0.9004
778 3SL 0.9002
779 280 0.9002
780 JBQ 0.8999
781 DMG 0.8999
782 5WX 0.8997
783 6X8 0.8997
784 MAQ 0.8996
785 BEW 0.8995
786 FBJ 0.8995
787 PIM 0.8995
788 UAN 0.8994
789 4J8 0.8993
790 HSE 0.8993
791 C2U 0.8993
792 MAN 0.8993
793 69O 0.8992
794 IF7 0.8991
795 KIV 0.8991
796 495 0.8990
797 FCA 0.8990
798 PEL 0.8990
799 2FG 0.8990
800 DHK 0.8989
801 JZ5 0.8988
802 DOR 0.8987
803 INE 0.8986
804 SIN 0.8986
805 ISE 0.8986
806 ADK 0.8983
807 52C 0.8983
808 HZQ 0.8982
809 M6W 0.8981
810 J9N 0.8981
811 PRF 0.8981
812 1IT 0.8979
813 PYQ 0.8978
814 WOO 0.8978
815 PMB 0.8977
816 CN0 0.8976
817 GDE 0.8976
818 L89 0.8976
819 P2D 0.8976
820 PRS 0.8975
821 OVP 0.8975
822 E1T 0.8975
823 1AN 0.8975
824 AL0 0.8974
825 4TU 0.8970
826 9X7 0.8969
827 LKA 0.8968
828 7MH 0.8967
829 3BU 0.8967
830 268 0.8966
831 PIY 0.8965
832 DIU 0.8964
833 SHG 0.8964
834 LCN 0.8963
835 TAR 0.8962
836 KPL 0.8962
837 NDM 0.8961
838 DUB 0.8961
839 9CL 0.8958
840 EXO 0.8957
841 HTS 0.8956
842 938 0.8956
843 NID 0.8955
844 IP0 0.8953
845 GAF 0.8953
846 G4D 0.8953
847 8LG 0.8952
848 4ME 0.8952
849 2F6 0.8952
850 AW5 0.8951
851 3IT 0.8950
852 GVG 0.8948
853 MLI 0.8947
854 QY9 0.8945
855 4XX 0.8945
856 5WY 0.8944
857 F4E 0.8943
858 92Z 0.8943
859 3MH 0.8943
860 93Q 0.8943
861 FUM 0.8942
862 X05 0.8940
863 T9G 0.8940
864 TYL 0.8939
865 VAL 0.8938
866 0FN 0.8937
867 X6X 0.8937
868 GZL 0.8936
869 APG 0.8936
870 FP2 0.8935
871 GOO 0.8933
872 RM4 0.8933
873 PD2 0.8932
874 ALL 0.8930
875 39A 0.8926
876 3R6 0.8925
877 7ZE 0.8924
878 FA1 0.8924
879 PEP 0.8923
880 SKM 0.8923
881 LSA 0.8922
882 23J 0.8921
883 FRU 0.8921
884 PA1 0.8921
885 PRY 0.8920
886 THE 0.8920
887 DS0 0.8920
888 K17 0.8919
889 RBL 0.8919
890 S76 0.8917
891 34D 0.8914
892 2AF 0.8914
893 BMA 0.8914
894 Z6J 0.8911
895 PAF 0.8909
896 2RH 0.8909
897 149 0.8909
898 FUD 0.8908
899 JZ4 0.8907
900 ICB 0.8906
901 25T 0.8904
902 2ZQ 0.8903
903 6FZ 0.8903
904 MSR 0.8903
905 TMT 0.8902
906 45L 0.8901
907 EVA 0.8901
908 FUF 0.8900
909 QSH 0.8900
910 9RW 0.8899
911 9TY 0.8899
912 6KT 0.8899
913 JZ0 0.8898
914 R2B 0.8898
915 JFD 0.8897
916 9ZE 0.8896
917 K5W 0.8896
918 MRZ 0.8894
919 285 0.8891
920 H3M 0.8890
921 SMN 0.8890
922 ASN 0.8890
923 SRO 0.8890
924 76X 0.8889
925 GXL 0.8889
926 QPR 0.8888
927 HX2 0.8888
928 258 0.8887
929 BNS 0.8887
930 9FE 0.8886
931 D1X 0.8886
932 YHO 0.8886
933 HA7 0.8886
934 XYL 0.8883
935 APZ 0.8881
936 4SD 0.8881
937 AMS 0.8880
938 TT4 0.8880
939 TBP 0.8880
940 4FH 0.8879
941 A13 0.8879
942 F12 0.8878
943 INS 0.8878
944 8G0 0.8877
945 FBT 0.8877
946 1U6 0.8877
947 ARA 0.8876
948 9YL 0.8876
949 ESX 0.8875
950 1AL 0.8874
951 DHS 0.8872
952 D07 0.8871
953 IJZ 0.8871
954 SS2 0.8871
955 DMJ 0.8870
956 NXA 0.8870
957 PFB 0.8869
958 COI 0.8868
959 L5V 0.8868
960 C5J 0.8868
961 RNS 0.8868
962 PYJ 0.8868
963 SR1 0.8867
964 YTB 0.8866
965 HPY 0.8865
966 NCT 0.8864
967 URQ 0.8864
968 0F9 0.8864
969 PXM 0.8864
970 TBS 0.8863
971 SLS 0.8863
972 ICC 0.8863
973 7ME 0.8861
974 B24 0.8861
975 DNF 0.8860
976 APY 0.8860
977 FGZ 0.8859
978 PHE 0.8858
979 GIV 0.8858
980 HIU 0.8857
981 3MA 0.8856
982 92P 0.8856
983 6LW 0.8854
984 1XX 0.8854
985 YIO 0.8854
986 BNF 0.8853
987 3V4 0.8852
988 OHP 0.8852
989 1DH 0.8851
990