Receptor
PDB id Resolution Class Description Source Keywords
5E9L 1.9 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF BAZ2B BROMODOMAIN IN COMPLEX WITH FRAGM HOMO SAPIENS FOUR HELICAL BUNDLE TRANSCRIPTION
Ref.: HIGH-THROUGHPUT FRAGMENT DOCKING INTO THE BAZ2B BRO EFFICIENT IN SILICO SCREENING FOR X-RAY CRYSTALLOGR ACS CHEM.BIOL. V. 11 800 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
6AI A:2001;
Valid;
none;
submit data
133.151 C7 H7 N3 c1cc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4XUB 1.98 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN BAZ2B IN COMPL BAZ2-ICR CHEMICAL PROBE HOMO SAPIENS TRANSCRIPTION BROMODOMAIN ACETYLATED LYSINE BINDING PROTEIKIAA1476 WALP4 SGC STRUCTURAL GENOMICS CONSORTIUM
Ref.: STRUCTURE ENABLED DESIGN OF BAZ2-ICR, A CHEMICAL PR TARGETING THE BROMODOMAINS OF BAZ2A AND BAZ2B. J.MED.CHEM. V. 58 2553 2015
Members (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 4XUB ic50 = 1.07 uM 43D C19 H18 N8 Cc1cn(nn1)....
2 4XUA ic50 = 26 uM 43C C21 H18 N6 Cc1cn(nn1)....
3 5MGF Kd = 54 uM 7MW C9 H11 N O3 CCC(=O)c1c....
4 5E9I - F60 C8 H7 N O c1cc(cc2c1....
5 6FGT - D9T C14 H21 N3 O2 CN1C=C(C=C....
6 4NRB ic50 = 38 uM 2LX C13 H17 N O3 CNC(=O)c1c....
7 6FH6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
8 5MGG - 7MU C7 H7 Cl N2 O CNC(=O)c1c....
9 5ORB - JR6 C16 H19 N3 O2 S Cn1c(c2c(n....
10 4NRC ic50 = 241 uM 2LY C8 H9 N O3 S CNC(=O)c1c....
11 6FH7 - EN2 C17 H18 F N3 O3 CN1C=C(C=C....
12 5E9K - 5KX C3 H3 Cl N2 c1cnc([nH]....
13 4NRA Kd = 65 uM 2LW C13 H13 Cl N2 O CC(=O)N1CC....
14 5MGE Kd = 87 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
15 4NR9 - ALY C8 H16 N2 O3 CC(=O)NCCC....
16 5E9L - 6AI C7 H7 N3 c1cc2cn[nH....
17 5OR9 ic50 = 88 uM JR5 C18 H21 F N4 O3 S Cn1c(c2c(n....
18 5E74 Kd = 39 uM 5KH C25 H19 F3 N2 O3 Cc1ccc(cc1....
19 5E9M - BAE C6 H13 N O CC(C)(C)C(....
20 6FGU - D9Q C13 H19 N3 O2 CN1C=C(C=C....
21 5DYX - ADE C5 H5 N5 c1[nH]c2c(....
22 5DYU - MZ0 C4 H6 N2 O c1c([nH]cn....
23 5E73 Kd = 23 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
70% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 4XUB ic50 = 1.07 uM 43D C19 H18 N8 Cc1cn(nn1)....
2 4XUA ic50 = 26 uM 43C C21 H18 N6 Cc1cn(nn1)....
3 5MGF Kd = 54 uM 7MW C9 H11 N O3 CCC(=O)c1c....
4 5E9I - F60 C8 H7 N O c1cc(cc2c1....
5 6FGT - D9T C14 H21 N3 O2 CN1C=C(C=C....
6 4NRB ic50 = 38 uM 2LX C13 H17 N O3 CNC(=O)c1c....
7 6FH6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
8 5MGG - 7MU C7 H7 Cl N2 O CNC(=O)c1c....
9 5ORB - JR6 C16 H19 N3 O2 S Cn1c(c2c(n....
10 4NRC ic50 = 241 uM 2LY C8 H9 N O3 S CNC(=O)c1c....
11 6FH7 - EN2 C17 H18 F N3 O3 CN1C=C(C=C....
12 5E9K - 5KX C3 H3 Cl N2 c1cnc([nH]....
13 4NRA Kd = 65 uM 2LW C13 H13 Cl N2 O CC(=O)N1CC....
14 5MGE Kd = 87 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
15 4NR9 - ALY C8 H16 N2 O3 CC(=O)NCCC....
16 5E9L - 6AI C7 H7 N3 c1cc2cn[nH....
17 5OR9 ic50 = 88 uM JR5 C18 H21 F N4 O3 S Cn1c(c2c(n....
18 5E74 Kd = 39 uM 5KH C25 H19 F3 N2 O3 Cc1ccc(cc1....
19 5E9M - BAE C6 H13 N O CC(C)(C)C(....
20 6FGU - D9Q C13 H19 N3 O2 CN1C=C(C=C....
21 5DYX - ADE C5 H5 N5 c1[nH]c2c(....
22 5DYU - MZ0 C4 H6 N2 O c1c([nH]cn....
23 5E73 Kd = 23 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
50% Homology Family (389)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6JJ3 ic50 = 100 nM BS6 C23 H25 N5 O4 S CN1CCN(CC1....
2 6P05 ic50 = 5.9 nM YF2 C30 H28 N6 O3 S CCS(=O)(=O....
3 4IOO - BAE C6 H13 N O CC(C)(C)C(....
4 5I88 Kd = 250 nM 69G C20 H21 N3 O2 C/C=C/CN1C....
5 5DX4 Kd = 0.137 uM E0C C20 H17 Br N2 O4 S CCN1c2ccc(....
6 6JJB ic50 = 49.5 nM BT0 C19 H16 N2 O4 S CN1c2ccc(c....
7 3JVK Kd = 118 uM GLY GLY ALY ALA PRO ARG LYS GLN n/a n/a
8 4HBX ic50 = 1.9 uM 14X C13 H17 N3 O3 S CN1Cc2cc(c....
9 4NUE Ki = 0.15 uM NUE C19 H19 N5 O3 S Cc1cc(c(c(....
10 6SB8 Kd = 0.07 uM L45 C21 H27 N3 O5 S CCN(CC)S(=....
11 5Y94 Kd = 164 nM 8QC C16 H16 Br N3 O4 S Cc1c2cc(c(....
12 6DMJ - 53W C27 H32 N4 O3 Cc1c(c(on1....
13 4HXR ic50 = 4.1 uM 1A4 C13 H10 N2 O3 S3 c1cc(cc(c1....
14 6DML - 9BM C25 H26 N4 O4 Cc1c(c(on1....
15 5TI5 ic50 = 41 uM 7CN C16 H13 Br N2 O3 S c1cc(cc(c1....
16 6VUJ ic50 = 35.2 uM RLY C23 H30 N2 O5 S CCN(CC)S(=....
17 6X7B ic50 = 27 nM ZVP C26 H24 N4 O5 S c1cc(cnc1)....
18 4O7C ic50 = 10 uM 2RK C22 H23 N5 O C1CNCCC1C2....
19 4IOQ - BAQ C4 H7 N O C1CC(=O)NC....
20 4HXK - 1AJ C11 H11 N3 O S c1csc2c1CN....
21 6S6K Kd = 0.18 uM KXK C24 H31 N3 O5 S Cc1c2c(c([....
22 2YEL ic50 = 15.5 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
23 6RWJ Kd = 6.41 uM KLK C12 H16 N2 O2 Cc1c2c(c([....
24 6SA2 Kd = 0.08 uM L25 C22 H27 N3 O6 S Cc1c2c(c([....
25 6XV7 - O2Q C14 H13 F2 N5 Cc1nnc2n1n....
26 4BW4 ic50 = 631 nM 9B6 C22 H16 F3 N5 O4 Cc1c(c(on1....
27 4O72 ic50 = 1 uM 2R4 C25 H19 N O3 S c1ccc2c(c1....
28 5F63 Kd = 12 nM 5W2 C28 H35 Cl F N7 O3 S Cc1cnc(nc1....
29 5HLS ic50 = 0.039 uM 62G C20 H16 Cl N3 O2 Cc1c-2c(on....
30 4HBW ic50 = 4.8 uM 14Z C11 H15 N3 O3 S CCNS(=O)(=....
31 4OGI Kd = 37 nM R78 C28 H39 N7 O3 CC[C@@H]1C....
32 6WW8 - YR0 C31 H32 N6 O4 S CN(C)C(=O)....
33 5TI7 ic50 = 11 uM 7CQ C17 H19 Br N2 O4 S COc1ccc(cc....
34 4J0S ic50 = 0.382 uM 1H3 C18 H17 N O3 Cc1c(c(on1....
35 6Q3Y Kd = 54 nM HG5 C30 H38 N6 O2 CC[C@@H]1C....
36 6SAJ Kd = 0.05 uM L2Z C23 H27 N3 O6 S Cc1c2c(c([....
37 4F3I Kd = 36.1 nM 0S6 C20 H19 Cl N4 O2 S Cc1c(sc-2c....
38 4QZS Kd = 89 nM JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
39 6AFR ic50 = 70 nM 9E3 C13 H10 F N3 O c1cc2c(ccc....
40 4WIV Kd = 550 nM 3P2 C21 H23 N5 O Cc1c(c(on1....
41 6VUF ic50 = 147 uM RLV C14 H20 N2 O3 S CCCNS(=O)(....
42 3P5O Kd = 55.2 nM EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
43 4UIX ic50 = 0.00000001 M TVU C22 H24 N2 O6 S2 CN1C=C(c2c....
44 4HXS ic50 = 4.1 uM 1A3 C16 H14 N2 O3 S2 c1ccc(cc1)....
45 5HM0 ic50 = 0.44 uM 62V C18 H13 Cl N2 O Cc1c-2c(on....
46 5DLX Kd = 2 uM 5D2 C25 H33 Cl N8 O Cc1nnc2n1n....
47 5TI2 ic50 = 24 uM 7CJ C16 H15 F N2 O3 S c1cc(cc(c1....
48 5D3H Kd = 7.9 uM 57G C20 H27 N3 O6 S CCc1c(c([n....
49 6E4A Kd = 44 nM HRY C29 H34 Cl N7 O CN1C=C(C=C....
50 4MEP ic50 = 4.7 uM 24Y C19 H14 Cl N5 O Cc1cccnc1n....
51 4YH4 ic50 = 26 uM Y81 C20 H15 N3 O2 c1ccc(cc1)....
52 5D3N Kd = 9.2 uM L40 C18 H23 N3 O4 S CCc1c(c([n....
53 6C7R Kd = 2.2 nM EO4 C24 H25 N7 O2 Cc1c(c(on1....
54 6WGX ic50 = 0.15 uM U0D C31 H36 F3 N7 Cc1cc(cc(c....
55 6HOV - FER C10 H10 O4 COc1cc(ccc....
56 5D26 Kd = 0.81 uM L28 C19 H26 N4 O5 S CCc1c(c([n....
57 3MUK Kd = 380 uM ALA THR PRK ALA ALA ARG LYS SER n/a n/a
58 4J3I Kd = 8.93 uM 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
59 6X7D ic50 = 388 nM UT4 C19 H18 N2 O4 S c1cc2c(cc1....
60 4QB3 Kd = 3.4 uM 30M C17 H21 N3 O2 CC(=O)NCCC....
61 4LZS Kd = 16 uM L46 C11 H16 N2 O2 CCc1c(c([n....
62 6HDQ ic50 = 5.01 uM FZE C30 H37 F2 N5 O Cc1cc(cnc1....
63 4O71 ic50 = 18 uM CPB C21 H20 Cl N O5 C[N@]1CC[C....
64 4CFL Kd = 1.33 uM 8DQ C19 H18 N2 O2 c1ccc(cc1)....
65 4C67 - L5S C15 H12 N4 S Cc1nnc2n1-....
66 6V1K - 5SW C20 H23 N3 O3 CN1C=C(c2c....
67 4QR3 ic50 = 1.4 uM BNJ C14 H16 N2 O3 S2 c1cc(cc(c1....
68 4ZC9 - 4MW C38 H37 Cl N8 O7 S Cc1c(sc-2c....
69 4MEO - 25V C18 H16 N2 O2 Cc1cc(c2cc....
70 6UVM Kd = 510 uM QJA C11 H13 N O S2 CC(=O)N1CC....
71 4LRG ic50 = 0.026 uM 1XB C20 H18 Cl N3 O2 S Cc1c(sc-2c....
72 6CKS ic50 = 0.015 uM F5Y C23 H23 N3 O4 S CCS(=O)(=O....
73 6DJC Ki = 232.8 nM CF6 C48 H54 Cl2 N10 O2 S2 Cc1c(sc-2c....
74 5TI3 ic50 = 44 uM 7CG C16 H14 Br2 N2 O3 S c1cc(cc(c1....
75 4HXP - 1A5 C10 H10 N2 O3 c1cc(ccc1C....
76 6PSB ic50 = 24 uM Y18 C17 H19 N3 O2 CN1C[C@H](....
77 6CD4 ic50 = 5.14 uM EX1 C33 H42 N8 O3 CC(C)N1c2c....
78 4O7E ic50 = 5.7 uM 2RN C20 H15 N3 O c1ccc(cc1)....
79 4O74 ic50 = 0.025 uM R78 C28 H39 N7 O3 CC[C@@H]1C....
80 4BW2 ic50 = 6.31 uM UTH C24 H24 N4 O3 Cc1c(c(on1....
81 5CS8 ic50 = 2.29 uM EB8 C21 H18 N2 O5 S CCN1c2ccc(....
82 3U5J Kd = 2.46 uM 08H C17 H13 Cl N4 Cc1nnc2n1-....
83 5EIS Kd = 1.8 uM 5OU C14 H13 Cl N4 O2 CCn1cnc2c1....
84 6FO5 Kd = 0.19 uM DZH C25 H26 N6 O5 S CCn1cnc2c1....
85 6V1L Kd = 418 nM 5U6 C20 H23 N3 O3 CN1C=C(c2c....
86 3U5L Kd = 0.64 uM 08K C17 H14 Cl N5 Cc1nnc2n1-....
87 4QR4 ic50 = 0.25 uM BNK C14 H15 Cl N2 O3 S2 c1cc(c(cc1....
88 4O7A ic50 = 19 uM 2RF C16 H10 Cl2 N2 O3 c1cc(cc(c1....
89 5F61 Kd = 35 nM 5W0 C26 H34 F N7 O2 S Cc1cnc(nc1....
90 4HXN - 1A7 C9 H6 F N O S c1ccc(c(c1....
91 6DL2 Ki = 33 nM GUJ C17 H17 N3 O S Cc1c(c2c(s....
92 5Z5U - 96U C12 H10 N4 O2 c1cn(cn1)c....
93 5TI4 ic50 = 26 uM 7CM C16 H14 Cl F N2 O3 S c1cc(cc(c1....
94 5Y8C ic50 = 0.16 uM 8P9 C16 H15 Cl N2 O5 S Cc1c2cc(c(....
95 4NUD Ki < 0.0845 uM NUD C18 H17 N5 O3 S Cc1cc(c(cc....
96 4O7B ic50 = 20 uM 2RJ C26 H26 F N5 O Cc1cccc(c1....
97 5CPE ic50 = 0.45 uM EB2 C20 H24 N2 O3 S CCN1c2ccc(....
98 5MLI ic50 = 130 uM 82I C6 H8 Cl N3 O CNC1=C(C(=....
99 5DW2 Kd = 1.44 uM 5GD C24 H29 N3 O4 Cc1cc(cc(c....
100 5D3P Kd = 7.4 uM 57E C19 H21 N3 O4 S CCc1c(c([n....
101 4PCE ic50 = 7 uM 2N0 C17 H19 N O CCc1cc2c(n....
102 5D25 Kd = 0.46 uM 56M C19 H25 N3 O5 S CCN(CC)S(=....
103 5DLZ Kd = 1.8 uM 5D1 C28 H35 N3 O3 Cc1cccc(c1....
104 5Y8W ic50 = 0.23 uM 8PU C15 H13 Br N2 O5 S Cc1c2cc(c(....
105 4J0R ic50 = 0.386 uM 1H2 C18 H17 N O3 Cc1c(c(on1....
106 6MH7 ic50 = 1.3 uM JQY C26 H27 F N6 Cc1ccc(cc1....
107 5F60 Kd = 43 nM 5VZ C26 H34 Cl N7 O2 S Cc1cnc(nc1....
108 5Z5V ic50 = 287 nM 96X C15 H14 N4 O2 CC(=O)Nc1c....
109 4HXO - 1A6 C11 H10 N4 O S Cc1cc(on1)....
110 5CRM ic50 = 1.09 uM EB5 C15 H16 N2 O3 S CCNS(=O)(=....
111 6YQN ic50 = 0.72 uM P8T C32 H28 Cl N7 O2 S Cc1c(sc-2c....
112 5CQT Kd = 0.124 uM EB3 C19 H22 N2 O3 S CCN1c2ccc(....
113 5KHM Ki = 5.012 nM XNH C25 H33 N7 O3 C[C@@H]1C(....
114 6XV3 - O2B C28 H33 N9 O Cc1nnc2n1c....
115 4Z1S ic50 = 0.79 uM 559 C23 H21 Cl N6 Cc1nnc2n1-....
116 4MR3 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
117 5MKZ ic50 = 20 uM RNK C11 H12 Cl N3 O S Cc1ccsc1CN....
118 5ULA Ki = 77 nM 5MJ C20 H19 Cl N2 O3 CC1=C(CCC1....
119 4O78 ic50 = 4.6 uM SAV C21 H22 N6 O3 Cc1c2ccc(c....
120 6XVC - O32 C22 H21 N5 O2 Cc1nnc2n1c....
121 4OGJ Kd = 164 nM 2TA C27 H36 N6 O3 S Cc1cnc(nc1....
122 5A85 ic50 = 5.01 uM 78J C21 H30 N4 O2 CC1=Cc2ccn....
123 5TI6 ic50 = 21 uM 7CO C16 H14 F2 N2 O3 S c1cc(cc(c1....
124 6MAU - JBS C30 H32 N6 O3 Cc1c(c(on1....
125 6S4B Kd = 0.14 uM KUH C22 H29 N3 O5 S CCN(CC)S(=....
126 6Q3Z Kd = 44 nM HG8 C29 H38 N6 O2 S CC[C@@H]1C....
127 6V0U Kd = 392 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
128 6VUC ic50 = 144 uM RLS C16 H22 N2 O3 S CN1C[C@H](....
129 4MR4 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
130 4QR5 ic50 = 0.06 uM BNM C18 H21 N3 O4 S2 c1c(cc(cc1....
131 4MEQ - 25O C12 H11 N5 Cc1cc(n2c(....
132 4O77 ic50 = 2.5 uM 2RE C20 H14 F N3 O c1cc(ccc1c....
133 6XUZ - O1W C24 H33 N9 O2 Cc1nnc2n1c....
134 5EI4 ic50 = 26.4 uM 5NV C17 H17 Cl N8 O2 S CCn1c(nc2c....
135 5CY9 Kd = 0.218 uM E0A C17 H20 N2 O3 S CCCCS(=O)(....
136 6MH1 ic50 = 1.7 uM JQP C26 H27 F N6 Cc1cc(cc(c....
137 5CRZ ic50 = 0.45 uM EB7 C19 H14 Cl F N2 O3 S CCN1c2ccc(....
138 5Y93 ic50 = 2.27 uM 8Q9 C23 H27 Br N4 O7 S Cc1c2cc(c(....
139 5AD2 Kd = 63 nM ETU C24 H30 Cl N7 O2 C[C@@H]1C(....
140 4E96 ic50 = 0.22 uM 0NS C16 H17 N3 O4 S CN1Cc2cc(c....
141 5D0C Kd = 2.34 uM E0B C21 H25 N3 O4 S CCN1c2ccc(....
142 4O7F ic50 = 13 uM 2RQ C25 H24 F N5 O2 COc1ccccc1....
143 5CP5 Kd = 1.234 uM EB0 C19 H15 F N2 O3 S CCN1c2ccc(....
144 4CFK Kd = 1.83 uM LY2 C19 H17 N O3 c1ccc(cc1)....
145 5D3R - 57C C23 H31 N3 O4 S CCCc1c(c([....
146 4NUC Ki = 0.91 uM 435 C19 H18 N4 O3 S Cc1cc(cc(c....
147 4HXL ic50 = 2.2 uM 1A9 C22 H25 N3 O4 S3 c1cc(sc1)S....
148 6CIY ic50 = 0.41 uM F3J C34 H42 N8 O3 CN1CCN(CC1....
149 5D3L Kd = 0.88 uM 57F C21 H29 N3 O5 S CCc1c(c([n....
150 4A9L - P9L C14 H19 N3 O4 S CN1Cc2cc(c....
151 4XYA Kd = 1370 nM 43S C13 H8 Br N5 O c1coc2c1cc....
152 4C66 - H4C C17 H16 Cl N4 S CCc1cc2c(s....
153 6UWU ic50 ~ 70 nM QKP C27 H34 N2 O6 Cc1cc(cc(c....
154 4O76 ic50 = 0.13 uM 1M3 C26 H35 N7 O2 S Cc1cnc(nc1....
155 5LJ2 ic50 = 10 uM 6XW C25 H32 N6 O4 S CC1=Cc2c(c....
156 6CD5 - R4L C35 H44 N8 O3 CN1CCN(CC1....
157 5I80 Kd = 62 nM 67B C17 H17 N3 O2 CN1C=C(c2c....
158 4O75 ic50 = 21 uM 2RC C23 H26 F N6 O9 P CC1(C(=O)N....
159 5NNF - PHE LEU PRO HIS ALY TYR ASP VAL LYS LEU n/a n/a
160 3ZYU ic50 = 0.1 uM 1GH C23 H21 N5 O3 Cc1c(c(on1....
161 4Z1Q ic50 = 0.015 uM 558 C23 H21 Cl N6 Cc1nnc2n1-....
162 6SA3 Kd = 0.42 uM L2N C23 H30 N4 O5 S Cc1c2c(c([....
163 5IGK Kd = 41.8 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
164 5Y1Y ic50 = 0.98 uM HNQ C9 H6 N2 O3 c1cc2c(ccc....
165 5Z5T - 96R C12 H10 N4 O c1cc2c(cc(....
166 6V1U - QMG C20 H19 N3 O2 Cc1ccc(cc1....
167 5KDH Ki = 0.37 uM 6RX C18 H17 N3 O4 CCN1C2=C([....
168 4PS5 ic50 = 0.29 uM 2TA C27 H36 N6 O3 S Cc1cnc(nc1....
169 5D24 Kd = 5.8 uM L26 C18 H21 N3 O4 CCc1c(c([n....
170 5ACY Kd = 6.4 nM 9S3 C30 H35 N3 O C[C@H]1C[C....
171 5HCL ic50 = 6 mM 5Y9 C4 H9 N O CC(=O)N(C)....
172 5COI ic50 = 2.58 uM 55K C20 H22 N2 O5 S CCN1c2ccc(....
173 6UWX Kd = 290 uM QKD C12 H17 N O2 S2 CCOC(=O)N1....
174 5Y8Y Kd = 82 nM 8PX C16 H15 Br N2 O5 S Cc1c2cc(c(....
175 4HXM ic50 = 0.79 uM 1A8 C17 H17 N3 O4 S3 CCCC(=O)Nc....
176 5F62 Kd = 6.8 nM 5W1 C26 H33 Cl F N7 O2 S Cc1cnc(nc1....
177 5D3S Kd = 1.3 uM 579 C20 H24 F N3 O5 S CCc1c(c([n....
178 6YQP ic50 = 1.35 uM P8N C29 H27 Cl N6 O3 S Cc1c(sc-2c....
179 6AJX Kd = 9.1 uM HCC C15 H12 O4 c1cc(ccc1C....
180 4LYW Kd = 237 nM 21Q C20 H27 N3 O5 S CCc1c(c([n....
181 4HBV ic50 = 23 uM 15E C9 H9 Br N2 O CN1Cc2cc(c....
182 5LUU Kd = 8.63 uM 77X C15 H17 N3 O CCC(=O)N1C....
183 4YH3 ic50 = 26 uM Y80 C24 H20 N2 O3 COc1ccc(cc....
184 6AJV Kd = 9.1 uM HCC C15 H12 O4 c1cc(ccc1C....
185 6CZV ic50 = 0.23 uM FOY C17 H16 N2 O2 Cc1c(c(on1....
186 4X2I ic50 = 0.35 uM 3X0 C18 H17 Cl N4 Cc1nnc2n1-....
187 6CJ1 ic50 = 6.31 uM FND C34 H44 N8 O3 CC[C@H](C)....
188 5F5Z Kd = 86 nM 5VY C26 H35 N7 O2 S Cc1cnc(nc1....
189 6UVJ Kd = 20 uM QJ1 C11 H15 N O2 S2 COC(=O)N1C....
190 6FNX ic50 = 12.6 uM DYZ C14 H14 N4 O2 CCn1cnc2c1....
191 4HBY ic50 = 4.4 uM 13F C15 H15 N3 O3 S CN1Cc2cc(c....
192 5D3J Kd = 5.7 uM L33 C20 H27 N3 O4 S CCc1c(c([n....
193 6AJY Kd = 5.3 uM A0R C16 H14 O4 COc1ccccc1....
194 3MUL - GLY GLY BTK ALA PRO ARG LYS GLN n/a n/a
195 4LR6 ic50 = 33 uM 1XA C10 H10 N2 O Cc1c(c(on1....
196 5AD3 Kd = 7.9 nM K6K C26 H30 N10 O3 CN(CCOc1cc....
197 4PCI ic50 = 7.5 uM 2NJ C16 H16 N2 O CN1c2ccccc....
198 5D3T Kd = 12 uM 56Y C19 H23 N3 O3 CCc1c(c([n....
199 6SAH Kd = 0.26 uM L2W C23 H29 N3 O5 S Cc1c2c(c([....
200 5LJ1 ic50 > 0.0000316 M 6XX C28 H35 F2 N5 O3 Cc1cc(cnc1....
201 4O70 ic50 = 19 uM 1QK C21 H29 N6 O2 CCc1cnn2c1....
202 4XY9 Kd = 4651 nM 43U C12 H10 Br N5 O COc1ccc(cc....
203 3MXF - JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
204 5CFW Kd = 0.78 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
205 5A5S ic50 = 1.3 uM NP8 C20 H23 N5 O2 CC1=Cc2c(c....
206 4UIY ic50 = 0.00000001 M 5V2 C21 H20 F3 N3 O3 S2 CN1C=C(c2c....
207 6PS9 ic50 = 79 uM Y17 C18 H21 N3 O2 CN1C[C@@H]....
208 4LZR Kd = 20 uM LOC C22 H25 N O6 CC(=O)N[C@....
209 6PRT ic50 = 2120 uM OWA C8 H13 N O3 CN1C[C@H](....
210 4BW1 ic50 = 1.26 uM S5B C25 H25 N3 O3 Cc1c(c(on1....
211 6YQO ic50 = 4.53 uM P8Q C33 H36 Cl N7 O4 S Cc1c(sc-2c....
212 4MEN - 25K C15 H17 N5 Cc1ccc(cc1....
213 6CIS ic50 = 0.3 uM X26 C37 H48 N8 O3 CC(C)Oc1cc....
214 6CKR ic50 = 0.05 uM F5V C21 H20 N4 O3 S Cn1cc(cn1)....
215 4UIZ ic50 = 0.00001995 M N1D C22 H25 N3 O6 S2 CN1C=C(c2c....
216 5KJ0 ic50 = 130 nM 6TB C29 H41 N7 O3 CC[C@@H]1C....
217 4KV1 - THR PHE ALY SER ILE MET LYS n/a n/a
218 5EGU Kd = 1.4 uM 5NQ C23 H32 N8 O2 S CCCCc1c(nc....
219 5Y8Z ic50 = 0.62 uM 8Q3 C16 H15 Br N2 O4 S Cc1cc2c(cc....
220 6VUB ic50 = 629 uM RLG C11 H13 N O CN1C[C@H](....
221 4BW3 ic50 = 501 nM 9BM C25 H26 N4 O4 Cc1c(c(on1....
222 3U5K - 08J C18 H13 Cl F N3 Cc1ncc2n1-....
223 6FGH - 6RZ C10 H16 N2 O2 S Cc1c(cccn1....
224 6FG6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
225 6FGG Kd = 17 uM D9B C18 H20 N4 O4 CN1C=C(C=C....
226 5MGJ Kd = 51 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
227 6FGV - D9T C14 H21 N3 O2 CN1C=C(C=C....
228 6FGL ic50 = 24 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
229 5OR8 - JR4 C17 H18 F N3 O3 S Cc1cc2c(cc....
230 5FE0 - ALY C8 H16 N2 O3 CC(=O)NCCC....
231 5LVR Kd = 250 uM 78Y C10 H10 N4 O Cc1c(nn(n1....
232 5FDZ Kd = 6.8 uM 5X0 C21 H24 N2 O5 CNC(=O)c1c....
233 5FE1 - 12Q C10 H9 N O CN1c2ccccc....
234 5FE6 Kd = 6910 uM 5WZ C9 H16 N2 O C1CC1C(=O)....
235 5FE2 - 5WV C9 H9 N O CN1Cc2cccc....
236 5FE7 Kd = 488 uM 5WU C10 H14 N2 O2 Cc1c2c(n(n....
237 5FE8 - 5WT C13 H14 N2 O2 CC1=CC(=O)....
238 5FE4 - 5WY C9 H9 N O3 c1cc(c2c(c....
239 5FE9 Kd = 20.98 uM 5WS C12 H14 N2 O3 S CC1=CC(=O)....
240 5FE5 - 2QC C9 H9 N3 S c1cc(ccc1C....
241 5MKX ic50 = 20 uM 82I C6 H8 Cl N3 O CNC1=C(C(=....
242 5LVQ Kd = 73 uM 2LX C13 H17 N O3 CNC(=O)c1c....
243 5FE3 - 5WX C8 H8 N2 O2 COc1cccc2c....
244 6C7Q - EO1 C25 H23 N7 O2 Cc1c(c(on1....
245 2YEM ic50 = 15.5 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
246 5JWM ic50 = 3.09 nM 6ON C54 H66 Cl2 N10 O9 S2 Cc1c(sc-2c....
247 5UOO Ki = 1.4 nM 8FV C26 H21 N5 O2 Cc1c(c(on1....
248 3QZS Kd = 99 uM LYS GLY GLY ALA ALY ARG HIS ARG LYS VAL n/a n/a
249 3QZT - LYS GLY GLY ALA ALY ARG HIS ARG LYS VAL n/a n/a
250 5U6V ic50 = 21 nM 7WY C22 H19 Cl N6 Cc1c-2n(nn....
251 5O3A - 31P C23 H23 Cl N4 O3 CC[C@H]([C....
252 5DFD - 59E C23 H21 N5 O3 Cc1nnc2n1-....
253 5XHK - LDR C13 H9 N O c1ccc2c(c1....
254 5O3D - 9J5 C23 H23 Cl N4 O3 CC[C@H]([C....
255 6YTM Kd = 65 nM PMW C22 H25 Cl N4 O2 S CC[C@H]([C....
256 6VIY Ki = 1.1 nM QYY C27 H29 N3 O5 S CCNC(=O)c1....
257 5IG6 Kd = 213.7 uM 6B3 C27 H18 N2 O4 c1ccc2c(c1....
258 5O3G - 9J8 C25 H26 Cl N5 O2 CCNC(=O)[C....
259 4J1P Kd = 0.206 uM 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
260 5O3I - 9HN C27 H29 Cl N4 O3 Cc1nnc2n1-....
261 5UEW - 87D C20 H20 N2 O5 S CN1C=C(C(=....
262 5O3B - 9HZ C24 H23 Cl N4 O3 Cc1nnc2n1-....
263 5O3E - 9HW C23 H24 Cl N5 O2 CCNC(=O)[C....
264 3ONI - JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
265 6K04 Ki = 3.1 nM CQF C22 H21 Cl N6 Cc1nnc2n1-....
266 5O39 - 31O C22 H21 Cl N4 O3 Cc1nnc2n1-....
267 5O3H - 9HQ C23 H24 Cl N5 O2 CCNC(=O)[C....
268 5O3C - 9J2 C22 H21 Cl N4 O3 Cc1nnc2n1-....
269 4MR6 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
270 6MOA Kd = 2.5 nM JW4 C25 H22 N4 O Cc1ccc2c(c....
271 5DW1 ic50 = 0.08 uM 5GD C24 H29 N3 O4 Cc1cc(cc(c....
272 5DFC - EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
273 4MR5 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
274 5O3F - 9HT C24 H26 Cl N5 O2 CC[C@H]([C....
275 2WP1 - LYS ALA PRO ARG ALY GLN LEU ALA THR LYS n/a n/a
276 4FLP Kd = 190.1 nM JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
277 4KCX Kd = 37 uM 1QK C21 H29 N6 O2 CCc1cnn2c1....
278 4A9I - P9I C15 H13 N2 O C/C(=C/1C=....
279 4UYH ic50 = 0.00000001 M 9S3 C30 H35 N3 O C[C@H]1C[C....
280 4A9H - TVP C12 H15 N O C[C@H]1CCc....
281 4A9F - MB3 C5 H9 N O CN1CCCC1=O
282 4ALG ic50 = 0.5 uM 1GH C23 H21 N5 O3 Cc1c(c(on1....
283 2YEK ic50 = 32.5 nM EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
284 2YDW Kd = 46 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
285 4A9J - TYL C8 H9 N O2 CC(=O)Nc1c....
286 4A9M ic50 = 0.5 uM P9M C17 H22 N2 O3 S Cc1ccc(cc1....
287 4ALH - A9P C11 H11 N O Cc1c(c(on1....
288 4A9E - 3PF C9 H10 N2 O CN1Cc2cccc....
289 4A9O - A9O C12 H13 N O CCc1c(c(no....
290 4AKN ic50 = 0.79 uM S5B C25 H25 N3 O3 Cc1c(c(on1....
291 4A9N ic50 = 1.5 uM A9N C15 H16 N2 O3 S Cc1ccc(cc1....
292 4KV4 - THR PHE ALY SER ILE MET LYS n/a n/a
293 5UEZ Ki = 970 nM 89G C18 H16 N2 O3 CN1C(=O)C=....
294 6VIX Ki = 1.3 nM QYV C24 H21 F2 N3 O5 S CCNC(=O)c1....
295 5UF0 Ki = 160 uM 89J C12 H13 N3 O CNC1=CC(=O....
296 5UEU - 0S6 C20 H19 Cl N4 O2 S Cc1c(sc-2c....
297 4Z93 Kd = 44.6 nM 4LD C24 H23 N5 O2 Cc1c(c(n[n....
298 5UEY Ki = 5.1 nM 88M C22 H24 F2 N2 O5 S CCOC1=CC(=....
299 5UEX Ki = 1.5 nM 89D C24 H26 F2 N2 O5 S CCS(Nc1ccc....
300 5I8B ic50 = 0.11 uM 69F C23 H22 N2 O2 C[C@@H]1CC....
301 5I8G Kd = 0.03 uM 69E C22 H22 N6 O C[C@@H]1CC....
302 5N18 Kd = 2.1 uM 8HZ C21 H19 N3 O Cc1ccc(cc1....
303 5MLJ Ki = 1.4 nM 9ST C17 H21 Br N4 O CN1C[C@H](....
304 6J3P Kd = 105 nM B8O C21 H25 N5 O3 CN1C[C@H](....
305 6AXQ ic50 = 99000 nM C2Y C10 H9 N O2 COC(=O)c1c....
306 5DBM Kd = 0.35 uM 58N C17 H22 N4 O C[C@@H]1CC....
307 5LPM Kd = 2.77 uM 71Y C20 H23 Cl N2 O3 CCc1c(c([n....
308 5NRW - 96N C21 H22 N2 O2 CCc1c(c([n....
309 3P1D - MB3 C5 H9 N O CN1CCCC1=O
310 5LPJ Kd = 10.1 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
311 6FQO ic50 = 0.14 uM E2T C26 H24 N2 O6 CCOc1ccc(c....
312 4TQN Kd = 0.77 uM UL4 C18 H17 N O5 CCOc1ccc(c....
313 6FRF ic50 = 0.04 uM E3T C26 H24 N2 O5 CCOc1ccc(c....
314 5TB6 Kd = 1.53 uM 77X C15 H17 N3 O CCC(=O)N1C....
315 5MQK - QPR C11 H11 N O CC(=O)c1cn....
316 5MQG - F31 C9 H11 N O2 CC(=O)c1cc....
317 5I83 ic50 = 4.1 uM 68Y C18 H20 N2 O2 C[C@@H]1CC....
318 4A9K - TYL C8 H9 N O2 CC(=O)Nc1c....
319 5I86 ic50 = 0.53 uM 69A C18 H19 N3 O2 C[C@@H]1CC....
320 6FR0 ic50 = 0.146 uM E3H C27 H26 N2 O6 CCN1C(=O)C....
321 5NU5 Kd = 0.47 uM 99E C21 H22 N2 O4 CCc1c(c([n....
322 5LPK Kd = 3.06 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
323 5MME Kd = 1.4 uM 8Q6 C20 H21 N O6 CCOc1ccc(c....
324 5I89 ic50 = 0.033 uM 69B C21 H22 N4 O C[C@@H]1CC....
325 5NU3 Kd = 0.23 uM 99E C21 H22 N2 O4 CCc1c(c([n....
326 5OWK - 7MX C9 H10 Cl N O3 CCOC(=O)C1....
327 6AY5 ic50 = 69 nM C3V C22 H20 F2 N4 O S Cn1cc(cn1)....
328 5LPL Kd = 12 uM 71X C20 H23 Cl N2 O3 CCc1c(c([n....
329 6FQU ic50 = 2.2 uM E3B C21 H23 F2 N O2 CCOc1ccc(c....
330 6DMK - 2LL C26 H30 N4 O2 Cc1c(c(on1....
331 5MMG Kd = 0.97 uM UT0 C19 H20 N2 O4 S CCOc1ccc(c....
332 5MPN Kd = 0.085 uM YE5 C17 H16 N4 O2 CCOc1ccc(c....
333 5J0D Kd = 134 nM 6F9 C27 H35 N3 O5 CCC(=O)N1C....
334 6AY3 ic50 = 9.5 nM C3J C24 H23 F2 N5 O CNC(=O)c1c....
335 5MPK Kd = 0.003 uM 0BC C21 H18 N6 O3 S CCOc1ccc(c....
336 5CGP Kd = 0.12 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
337 4BJX ic50 = 22 nM 73B C25 H23 Cl N2 O3 C[C@H]1C[C....
338 4UYD ic50 = 79.4 uM V1T C10 H11 N3 O2 CN1c2ccc(c....
339 4XUB ic50 = 1.07 uM 43D C19 H18 N8 Cc1cn(nn1)....
340 4XUA ic50 = 26 uM 43C C21 H18 N6 Cc1cn(nn1)....
341 5MGF Kd = 54 uM 7MW C9 H11 N O3 CCC(=O)c1c....
342 5E9I - F60 C8 H7 N O c1cc(cc2c1....
343 6FGT - D9T C14 H21 N3 O2 CN1C=C(C=C....
344 4NRB ic50 = 38 uM 2LX C13 H17 N O3 CNC(=O)c1c....
345 6FH6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
346 5MGG - 7MU C7 H7 Cl N2 O CNC(=O)c1c....
347 5ORB - JR6 C16 H19 N3 O2 S Cn1c(c2c(n....
348 4NRC ic50 = 241 uM 2LY C8 H9 N O3 S CNC(=O)c1c....
349 6FH7 - EN2 C17 H18 F N3 O3 CN1C=C(C=C....
350 5E9K - 5KX C3 H3 Cl N2 c1cnc([nH]....
351 4NRA Kd = 65 uM 2LW C13 H13 Cl N2 O CC(=O)N1CC....
352 5MGE Kd = 87 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
353 4NR9 - ALY C8 H16 N2 O3 CC(=O)NCCC....
354 5E9L - 6AI C7 H7 N3 c1cc2cn[nH....
355 5OR9 ic50 = 88 uM JR5 C18 H21 F N4 O3 S Cn1c(c2c(n....
356 5E74 Kd = 39 uM 5KH C25 H19 F3 N2 O3 Cc1ccc(cc1....
357 5E9M - BAE C6 H13 N O CC(C)(C)C(....
358 6FGU - D9Q C13 H19 N3 O2 CN1C=C(C=C....
359 5DYX - ADE C5 H5 N5 c1[nH]c2c(....
360 5DYU - MZ0 C4 H6 N2 O c1c([nH]cn....
361 5E73 Kd = 23 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
362 7K6R - 9ST C17 H21 Br N4 O CN1C[C@H](....
363 7KDW - WCV C20 H21 N5 O C#CCNc1ncc....
364 7KDZ - WCS C22 H30 N6 O3 S CN(C)CCCOc....
365 7K6S - VYM C13 H16 N2 O c1cc2c(cc1....
366 5A7C ic50 = 0.00018 M 5D4 C10 H20 N2 O2 CC(=O)NCCC....
367 5TPX Kd = 280 nM 7H7 C21 H24 N6 Cc1nnc2n1n....
368 6MO8 - JWD C19 H17 N3 O2 Cc1c(c(on1....
369 6ONY - HWV C28 H30 F N3 O4 CCNC(=O)c1....
370 6JKE - BUX C13 H6 Cl2 N2 O4 c1cc(cc(c1....
371 6MO7 - JWA C19 H25 N3 O4 S Cc1ccc(cc1....
372 6MO9 - JVY C19 H21 N3 O3 S Cc1c(c(on1....
373 3AQA - BYH C17 H16 N4 S2 CN1c2ccccc....
374 6K05 Ki = 95.5 nM CQF C22 H21 Cl N6 Cc1nnc2n1-....
375 5WUU ic50 = 0.81 uM 7UU C18 H18 N2 O3 S CN(CCCNC1=....
376 5N17 Kd = 4.8 uM 8FK C19 H18 N2 O3 S CN1c2ccc(c....
377 5N16 Kd = 5 uM 8FN C22 H15 N5 O2 S c1ccc2c(c1....
378 6VIZ Ki = 120 nM QYY C27 H29 N3 O5 S CCNC(=O)c1....
379 6VIW Ki = 21.6 nM QYV C24 H21 F2 N3 O5 S CCNC(=O)c1....
380 5XXH ic50 = 6.8 uM E0D C18 H20 N2 O4 CC(=O)c1cn....
381 5ML0 - P2L C11 H17 Cl N4 O CN1CCC[C@H....
382 5W0L ic50 = 1.1 nM 9UD C27 H32 F2 N6 O2 CC(=O)N1CC....
383 5W0F ic50 = 16 nM 9U7 C25 H30 N6 O2 CC(=O)N1CC....
384 5W0E ic50 = 0.94 nM 9U4 C27 H33 F2 N7 O2 CNC(=O)N1C....
385 5W0Q ic50 = 18 uM 9UG C12 H16 N2 O2 Cc1ccc2c(c....
386 5W0I ic50 = 1.4 nM 9UA C26 H30 F2 N6 O2 CC(=O)N1CC....
387 5VOM ic50 = 0.79 uM 9GY C24 H23 N3 O4 C[C@H]1CN(....
388 2RI7 - ALA ARG THR MLY GLN THR ALA ARG LYS n/a n/a
389 6J3O Kd = 2.4 uM B4L C13 H19 N5 O CN1CCC[C@H....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 6AI; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 6AI 1 1
2 2K4 0.487805 0.685714
3 6NI 0.444444 0.609756
4 LZ1 0.435897 0.785714
Similar Ligands (3D)
Ligand no: 1; Ligand: 6AI; Similar ligands found: 1245
No: Ligand Similarity coefficient
1 11S 1.0000
2 5MI 1.0000
3 5H1 1.0000
4 5MB 1.0000
5 F60 1.0000
6 14O 1.0000
7 ES9 1.0000
8 BZX 1.0000
9 H4N 0.9961
10 FK1 0.9958
11 JAE 0.9930
12 8NY 0.9887
13 NPO 0.9836
14 JB5 0.9825
15 COU 0.9825
16 H42 0.9816
17 03V 0.9812
18 4FS 0.9810
19 ES5 0.9794
20 5OB 0.9790
21 2AQ 0.9782
22 OCH 0.9776
23 ABV 0.9772
24 AZA 0.9768
25 VGD 0.9766
26 XYP 0.9760
27 36R 0.9756
28 GUN 0.9754
29 XAN 0.9753
30 9DG 0.9750
31 BZ3 0.9749
32 LXC 0.9745
33 ET2 0.9743
34 AHR 0.9743
35 0CT 0.9738
36 CLW 0.9735
37 AZG 0.9730
38 QUZ 0.9729
39 6AP 0.9729
40 PHB 0.9729
41 BZI 0.9722
42 OAA 0.9722
43 RSF 0.9722
44 1PT 0.9721
45 A2F 0.9720
46 DEN 0.9719
47 5WV 0.9716
48 XQ0 0.9713
49 AX7 0.9713
50 6M9 0.9709
51 GLC 0.9706
52 5XC 0.9705
53 141 0.9705
54 MR1 0.9705
55 6GU 0.9704
56 BZF 0.9704
57 IND 0.9702
58 NPY 0.9700
59 ES2 0.9697
60 RM1 0.9696
61 1P7 0.9688
62 1P8 0.9685
63 M1A 0.9683
64 MCT 0.9681
65 0R1 0.9680
66 DMD 0.9679
67 3ID 0.9678
68 67N 0.9678
69 5VM 0.9675
70 ISN 0.9675
71 IGA 0.9674
72 HH5 0.9672
73 9EW 0.9670
74 0RW 0.9668
75 270 0.9663
76 GVH 0.9663
77 TH7 0.9663
78 1XM 0.9662
79 SAL 0.9661
80 MPI 0.9660
81 F05 0.9660
82 PAB 0.9659
83 DX4 0.9657
84 SVN 0.9657
85 P92 0.9655
86 HLR 0.9652
87 BOA 0.9652
88 5B1 0.9650
89 TH0 0.9648
90 F9Y 0.9647
91 0CU 0.9645
92 YCP 0.9641
93 7W4 0.9638
94 BAM 0.9637
95 FYU 0.9636
96 BEN 0.9634
97 BEZ 0.9633
98 2MI 0.9628
99 1DW 0.9625
100 IDM 0.9624
101 4HO 0.9623
102 6M4 0.9622
103 NOJ 0.9619
104 BGC 0.9619
105 URF 0.9618
106 HMH 0.9617
107 4SV 0.9615
108 KKN 0.9614
109 ES7 0.9614
110 YH7 0.9609
111 6PC 0.9608
112 8GC 0.9607
113 CFP 0.9600
114 HBD 0.9599
115 I3A 0.9598
116 7HQ 0.9597
117 3HB 0.9593
118 AZ8 0.9590
119 NCA 0.9584
120 QWN 0.9581
121 PE0 0.9575
122 3AB 0.9575
123 290 0.9574
124 BE2 0.9573
125 MEW 0.9572
126 MWM 0.9572
127 BCP 0.9570
128 MZG 0.9570
129 2CK 0.9567
130 GAB 0.9565
131 ISZ 0.9564
132 5CU 0.9562
133 3F0 0.9562
134 4XR 0.9562
135 TDR 0.9561
136 4JT 0.9560
137 5NU 0.9558
138 5JC 0.9554
139 1MC 0.9553
140 8H8 0.9550
141 LZM 0.9548
142 NTN 0.9547
143 5HN 0.9546
144 QXW 0.9546
145 3NT 0.9546
146 4JP 0.9546
147 5RG 0.9544
148 MLT 0.9543
149 K2T 0.9542
150 0R0 0.9542
151 J9W 0.9541
152 FBB 0.9540
153 2HQ 0.9540
154 NIO 0.9540
155 XBZ 0.9540
156 KOJ 0.9539
157 Q88 0.9537
158 717 0.9535
159 4M0 0.9535
160 173 0.9535
161 4ZE 0.9533
162 WBU 0.9532
163 XM0 0.9532
164 3U4 0.9531
165 14J 0.9529
166 NBZ 0.9529
167 HBA 0.9529
168 HPA 0.9529
169 4CL 0.9528
170 ES6 0.9527
171 42A 0.9527
172 1Y6 0.9527
173 5UC 0.9526
174 NK 0.9525
175 MWJ 0.9525
176 JBK 0.9522
177 JZ3 0.9520
178 27Y 0.9519
179 3HA 0.9518
180 HMU 0.9516
181 URC 0.9512
182 4CS 0.9511
183 JA8 0.9510
184 4JU 0.9510
185 Q24 0.9509
186 FDB 0.9509
187 4JJ 0.9508
188 53C 0.9507
189 SYV 0.9504
190 3M0 0.9504
191 5Q0 0.9501
192 5MH 0.9501
193 JZ9 0.9500
194 DBH 0.9499
195 24B 0.9499
196 FA0 0.9497
197 G3F 0.9495
198 5JQ 0.9494
199 DOB 0.9493
200 3PF 0.9493
201 TTL 0.9492
202 WCE 0.9490
203 VGL 0.9489
204 AC0 0.9488
205 BR9 0.9488
206 2AC 0.9485
207 12Q 0.9484
208 6MP 0.9483
209 KJH 0.9479
210 KUF 0.9479
211 EA1 0.9478
212 PZA 0.9478
213 FE DB1 0.9478
214 OVV 0.9478
215 5QX 0.9478
216 5QY 0.9477
217 FQI 0.9476
218 ES0 0.9476
219 86J 0.9475
220 ADE 0.9475
221 1WG 0.9472
222 BE7 0.9471
223 2YU 0.9471
224 24W 0.9471
225 2BG 0.9469
226 UNU 0.9464
227 5IQ 0.9463
228 NSP 0.9463
229 B53 0.9463
230 PBZ 0.9462
231 4HC 0.9462
232 GCS 0.9460
233 PBC 0.9456
234 275 0.9455
235 54D 0.9454
236 HQT 0.9453
237 BTE 0.9453
238 5SG 0.9452
239 G3E 0.9452
240 ES4 0.9452
241 M1Q 0.9451
242 2CQ 0.9450
243 A1U 0.9448
244 2MH 0.9448
245 1SQ 0.9446
246 Z82 0.9446
247 1NP 0.9446
248 CTL 0.9446
249 N5J 0.9444
250 XYS 0.9444
251 ICP 0.9442
252 0TR 0.9442
253 7W1 0.9441
254 23A 0.9441
255 BHA 0.9440
256 M5K 0.9440
257 174 0.9440
258 10L 0.9440
259 7B4 0.9440
260 PXL 0.9440
261 BTY 0.9438
262 P72 0.9438
263 E5X 0.9438
264 BHO 0.9437
265 XIY 0.9437
266 CWM 0.9437
267 LG4 0.9437
268 AJ2 0.9435
269 826 0.9434
270 GTQ 0.9434
271 3BZ 0.9433
272 B55 0.9433
273 9MG 0.9433
274 PM6 0.9432
275 3OC 0.9431
276 HQY 0.9430
277 7CZ 0.9430
278 G6D 0.9430
279 NIZ 0.9428
280 CWS 0.9428
281 4MA 0.9426
282 AQO 0.9426
283 6CS 0.9426
284 4YS 0.9425
285 XQG 0.9424
286 9HX 0.9424
287 0P6 0.9423
288 XYD 0.9423
289 1LQ 0.9422
290 9DA 0.9422
291 HT4 0.9422
292 4JO 0.9421
293 8ZE 0.9421
294 4HM 0.9421
295 43M 0.9419
296 HQE 0.9416
297 ADZ 0.9415
298 PLQ 0.9413
299 150 0.9412
300 SS1 0.9411
301 75K 0.9410
302 PRO 0.9410
303 82I 0.9410
304 OXQ 0.9409
305 ES1 0.9408
306 HIS 0.9408
307 I1E 0.9407
308 JKE 0.9407
309 4VP 0.9407
310 JZ2 0.9406
311 XAZ 0.9406
312 CRS 0.9406
313 BP1 0.9404
314 A7W 0.9404
315 JPZ 0.9404
316 NMJ 0.9404
317 UGC 0.9403
318 4ZC 0.9403
319 7HP 0.9402
320 DHB 0.9402
321 BRT 0.9401
322 2EC 0.9400
323 O72 0.9399
324 4XH 0.9396
325 CFI 0.9395
326 D48 0.9395
327 PCR 0.9395
328 45C 0.9395
329 SKA 0.9395
330 1M2 0.9394
331 34A 0.9390
332 ZZT 0.9389
333 PYD 0.9389
334 1WD 0.9387
335 5RN 0.9386
336 54G 0.9385
337 J1Z 0.9384
338 7WA 0.9382
339 DA1 0.9382
340 FPY 0.9380
341 7WV 0.9377
342 R8S 0.9376
343 TP5 0.9376
344 8S0 0.9376
345 TM7 0.9375
346 HY3 0.9375
347 KJU 0.9374
348 FOA 0.9371
349 HH8 0.9368
350 60P 0.9367
351 4HS 0.9367
352 XBT 0.9367
353 1LM 0.9366
354 FPN 0.9365
355 PXY 0.9365
356 8TX 0.9364
357 25R 0.9364
358 RCO 0.9364
359 5M0 0.9363
360 MQN 0.9362
361 H8N 0.9361
362 OVM 0.9359
363 2ZM 0.9359
364 QBK 0.9358
365 3SK 0.9358
366 6NT 0.9357
367 JBH 0.9357
368 FP1 0.9357
369 3XX 0.9356
370 5JL 0.9355
371 P3K 0.9355
372 SWD 0.9354
373 IFL 0.9352
374 GAG 0.9351
375 FAN 0.9350
376 8CM 0.9350
377 6RQ 0.9348
378 4P5 0.9348
379 IDH 0.9348
380 IUR 0.9347
381 CWJ 0.9344
382 3NY 0.9344
383 3MB 0.9343
384 2MP 0.9343
385 3DM 0.9341
386 GBD 0.9340
387 EQT 0.9339
388 VNJ 0.9339
389 MRW 0.9337
390 DYA 0.9336
391 1DU 0.9336
392 25W 0.9335
393 M1E 0.9333
394 J5I 0.9333
395 261 0.9333
396 3CH 0.9333
397 AMC 0.9333
398 51R 0.9331
399 INO 0.9331
400 HHA 0.9330
401 284 0.9329
402 4NC 0.9327
403 XX2 0.9327
404 TPA 0.9325
405 4JQ 0.9324
406 M58 0.9324
407 PY7 0.9324
408 1F1 0.9322
409 SE2 0.9321
410 URA 0.9321
411 5NI 0.9320
412 PYG 0.9320
413 DIN 0.9319
414 URP 0.9319
415 MYJ 0.9318
416 FUL 0.9318
417 B57 0.9317
418 0HN 0.9317
419 ICO 0.9317
420 282 0.9316
421 4YO 0.9315
422 0JD 0.9313
423 TIU 0.9313
424 2D0 0.9312
425 OK7 0.9310
426 LMR 0.9310
427 QSC 0.9310
428 PCA 0.9310
429 ABI 0.9309
430 P9P 0.9307
431 CYT 0.9307
432 SOE 0.9307
433 JBE 0.9306
434 Y8I 0.9303
435 BML 0.9302
436 GRE 0.9302
437 1DV 0.9301
438 ARB 0.9301
439 N2I 0.9300
440 9TZ 0.9295
441 HGQ 0.9295
442 PYC 0.9293
443 JLZ 0.9292
444 FPI 0.9292
445 SYN 0.9291
446 LG3 0.9291
447 BVF 0.9290
448 SX1 0.9289
449 8IG 0.9289
450 LT2 0.9289
451 RSO 0.9288
452 FUC 0.9288
453 0TU 0.9287
454 5AC 0.9287
455 4CH 0.9286
456 RIP 0.9286
457 NNO 0.9285
458 F81 0.9284
459 2HU 0.9284
460 GAL 0.9284
461 G2F 0.9284
462 3HM 0.9283
463 6M1 0.9283
464 BSX 0.9282
465 KDV 0.9282
466 HBX 0.9282
467 DFB 0.9281
468 0HO 0.9280
469 5MK 0.9279
470 GOJ 0.9278
471 4JN 0.9276
472 F4Z 0.9276
473 2PC 0.9274
474 AC6 0.9272
475 3ZQ 0.9271
476 286 0.9270
477 4AA 0.9268
478 FBM 0.9267
479 M2K 0.9266
480 FHB 0.9263
481 RHU 0.9261
482 2HO 0.9261
483 6F0 0.9261
484 B3R 0.9261
485 5GU 0.9260
486 WOT 0.9260
487 ZBT 0.9260
488 MBD 0.9260
489 4A3 0.9259
490 2ZV 0.9259
491 7VS 0.9259
492 M0W 0.9259
493 IT2 0.9259
494 HEW 0.9259
495 LG5 0.9258
496 ABN 0.9257
497 R8V 0.9256
498 JBN 0.9255
499 RIB 0.9254
500 1P3 0.9253
501 3FA 0.9253
502 265 0.9250
503 PKU 0.9250
504 E7Z 0.9250
505 0MK 0.9250
506 IV2 0.9249
507 TC7 0.9248
508 94W 0.9246
509 PZI 0.9246
510 93K 0.9245
511 7NI 0.9245
512 3Z7 0.9244
513 TLD 0.9243
514 FBA 0.9242
515 FCR 0.9242
516 PYF 0.9242
517 1XN 0.9242
518 JIF 0.9241
519 7WG 0.9240
520 JAW 0.9239
521 SW7 0.9238
522 3A9 0.9237
523 GYE 0.9237
524 C21 0.9235
525 26D 0.9235
526 IOL 0.9234
527 DFU 0.9234
528 KT7 0.9232
529 4JM 0.9232
530 4BZ 0.9232
531 M3T 0.9231
532 ASO 0.9230
533 DHR 0.9229
534 4WL 0.9227
535 QOS 0.9225
536 ANN 0.9225
537 8OZ 0.9225
538 C2B 0.9224
539 J9T 0.9223
540 3DO 0.9222
541 3Z8 0.9220
542 AKG 0.9220
543 PEA 0.9219
544 MZW 0.9217
545 K34 0.9214
546 8WO 0.9214
547 HX3 0.9214
548 SHA 0.9211
549 F9P 0.9211
550 7MU 0.9210
551 MNM 0.9209
552 2C9 0.9208
553 QSB 0.9207
554 JBQ 0.9207
555 3CE 0.9207
556 TZC 0.9205
557 HHQ 0.9205
558 EUG 0.9204
559 DRL 0.9203
560 CHB 0.9202
561 MUA 0.9202
562 CIG 0.9202
563 BCU 0.9200
564 4H2 0.9198
565 0W8 0.9198
566 273 0.9197
567 F5B 0.9196
568 4FA 0.9196
569 NQ 0.9194
570 DGJ 0.9192
571 NDH 0.9190
572 B62 0.9190
573 L3Q 0.9189
574 M0Q 0.9189
575 32X 0.9189
576 DBX 0.9188
577 AZ9 0.9185
578 BPN 0.9185
579 KJY 0.9185
580 ASP 0.9185
581 QX2 0.9184
582 3MC 0.9184
583 T6C 0.9184
584 9TW 0.9182
585 NOY 0.9182
586 HDH 0.9180
587 PHU 0.9180
588 QWW 0.9179
589 2CM 0.9179
590 TSS 0.9179
591 3RK 0.9179
592 M2H 0.9177
593 3FH 0.9176
594 3WA 0.9176
595 GMN 0.9174
596 RAM 0.9174
597 Q6T 0.9171
598 2A9 0.9170
599 MWP 0.9170
600 4JL 0.9170
601 9R5 0.9170
602 2H5 0.9170
603 GLA 0.9169
604 DUC 0.9169
605 SMV 0.9168
606 40O 0.9168
607 F0J 0.9167
608 J9Q 0.9167
609 R9S 0.9166
610 6MH 0.9165
611 CAQ 0.9165
612 GIO 0.9165
613 JAB 0.9163
614 2LP 0.9163
615 MAE 0.9163
616 XXR 0.9161
617 EKZ 0.9160
618 2CH 0.9160
619 TLA 0.9158
620 OXE 0.9158
621 8GF 0.9156
622 ODO 0.9155
623 35C 0.9154
624 LGC 0.9151
625 SRT 0.9150
626 OW4 0.9150
627 XRG 0.9150
628 FFP 0.9147
629 DHQ 0.9147
630 ABE 0.9146
631 ECE 0.9144
632 9FL 0.9143
633 JZ1 0.9143
634 G5V 0.9142
635 DTL 0.9142
636 2DR 0.9142
637 2MY 0.9141
638 PNZ 0.9140
639 L89 0.9140
640 BEW 0.9139
641 DE5 0.9137
642 SAN 0.9136
643 IFM 0.9135
644 8WT 0.9131
645 FLM 0.9130
646 XHP 0.9129
647 0FO 0.9129
648 JDN 0.9128
649 GIF 0.9128
650 OTW 0.9126
651 RXA 0.9126
652 UY7 0.9125
653 YRL 0.9124
654 42C 0.9123
655 M6N 0.9123
656 UNC 0.9123
657 AGK 0.9122
658 RMN 0.9122
659 TEO 0.9122
660 92K 0.9121
661 V55 0.9121
662 37T 0.9121
663 IPB 0.9120
664 TSU 0.9120
665 DUB 0.9119
666 4ZA 0.9116
667 6X8 0.9116
668 GCU 0.9115
669 92Z 0.9112
670 5WX 0.9112
671 NBE 0.9111
672 KYD 0.9110
673 BDP 0.9110
674 938 0.9110
675 XUL 0.9109
676 TGX 0.9108
677 AZF 0.9107
678 TMZ 0.9107
679 7N0 0.9104
680 HLZ 0.9102
681 IHB 0.9102
682 VK3 0.9102
683 JB8 0.9101
684 CTS 0.9101
685 93Q 0.9101
686 ALL 0.9101
687 2AK 0.9100
688 PBA 0.9100
689 1AN 0.9100
690 FBV 0.9099
691 23W 0.9098
692 HTS 0.9097
693 7MH 0.9095
694 8LG 0.9094
695 FB1 0.9094
696 DQU 0.9093
697 44W 0.9092
698 M1H 0.9092
699 MAK 0.9091
700 4M4 0.9091
701 OHG 0.9090
702 AEF 0.9089
703 QX4 0.9089
704 FB2 0.9089
705 5RO 0.9087
706 C2A 0.9087
707 TEP 0.9084
708 AAS 0.9082
709 OXZ 0.9082
710 MS9 0.9081
711 RM4 0.9081
712 1MR 0.9080
713 HQD 0.9079
714 SHG 0.9079
715 OVP 0.9078
716 BEA 0.9077
717 ADK 0.9077
718 FP2 0.9077
719 2AF 0.9076
720 LCN 0.9074
721 VNL 0.9073
722 6VD 0.9071
723 2FG 0.9071
724 280 0.9070
725 4Z4 0.9069
726 FCA 0.9069
727 3MH 0.9067
728 MO8 0.9065
729 SJ5 0.9065
730 WOO 0.9065
731 EXO 0.9065
732 JZ0 0.9064
733 H76 0.9063
734 N8Y 0.9060
735 IFP 0.9060
736 HSM 0.9060
737 76X 0.9059
738 PRZ 0.9058
739 IF7 0.9057
740 47J 0.9056
741 MT0 0.9056
742 OXC 0.9055
743 G4D 0.9053
744 TFB 0.9051
745 M4T 0.9049
746 IP0 0.9049
747 SWA 0.9048
748 HYP 0.9047
749 DIE 0.9046
750 TTY 0.9046
751 FBW 0.9045
752 LDU 0.9045
753 GLL 0.9045
754 GOO 0.9044
755 149 0.9043
756 PYQ 0.9042
757 L99 0.9042
758 XCZ 0.9040
759 KIV 0.9039
760 S76 0.9036
761 DMG 0.9035
762 F31 0.9034
763 44V 0.9033
764 GXY 0.9032
765 97T 0.9031
766 259 0.9030
767 HJP 0.9030
768 4XX 0.9030
769 ARA 0.9030
770 RB5 0.9028
771 B60 0.9027
772 LKA 0.9027
773 PA1 0.9026
774 YTB 0.9023
775 HIO 0.9022
776 MVN 0.9021
777 FOT 0.9021
778 2AL 0.9020
779 BP9 0.9018
780 MAN 0.9016
781 AKH 0.9015
782 39A 0.9015
783 15E 0.9015
784 LDP 0.9015
785 1DQ 0.9014
786 GAF 0.9014
787 PZM 0.9013
788 UAN 0.9013
789 HPY 0.9013
790 AJV 0.9012
791 HZQ 0.9012
792 X0V 0.9012
793 15N 0.9011
794 MLA 0.9011
795 HSO 0.9010
796 1SA 0.9010
797 INE 0.9009
798 C2U 0.9008
799 2A7 0.9006
800 BMA 0.9006
801 HY1 0.9005
802 4NM 0.9005
803 PAC 0.9005
804 4MU 0.9004
805 TBP 0.9004
806 R9Y 0.9004
807 2FY 0.9002
808 3IT 0.9002
809 DHK 0.9001
810 69O 0.9000
811 4ME 0.9000
812 A29 0.8997
813 JFD 0.8997
814 DIU 0.8997
815 GIV 0.8997
816 0N7 0.8996
817 OTR 0.8995
818 FCB 0.8995
819 DBJ 0.8994
820 ORO 0.8994
821 FUF 0.8994
822 K5W 0.8993
823 5WY 0.8993
824 HA5 0.8993
825 EYK 0.8992
826 YHO 0.8991
827 MXN 0.8989
828 9TY 0.8989
829 MNN 0.8988
830 9CA 0.8988
831 HSE 0.8986
832 PFB 0.8985
833 9X7 0.8984
834 PDC 0.8982
835 069 0.8981
836 DMJ 0.8981
837 INS 0.8980
838 1DJ 0.8979
839 PQ0 0.8978
840 NID 0.8978
841 6UA 0.8978
842 TMT 0.8977
843 1XX 0.8977
844 9CL 0.8975
845 JND 0.8975
846 J6W 0.8974
847 PRF 0.8974
848 495 0.8969
849 MAQ 0.8968
850 PEL 0.8968
851 BZ2 0.8966
852 KPL 0.8965
853 FBJ 0.8965
854 CXF 0.8963
855 SIN 0.8962
856 T9G 0.8962
857 JZ5 0.8961
858 MLI 0.8960
859 EVA 0.8960
860 X6X 0.8959
861 TAR 0.8956
862 AL0 0.8956
863 GXL 0.8955
864 3SL 0.8951
865 1LN 0.8951
866 4TU 0.8950
867 NDM 0.8948
868 94N 0.8948
869 PXM 0.8947
870 8K2 0.8946
871 GDE 0.8946
872 PMB 0.8945
873 1IT 0.8944
874 RNS 0.8944
875 YAN 0.8944
876 R8A 0.8943
877 F4E 0.8942
878 X05 0.8942
879 UEG 0.8942
880 52C 0.8942
881 GZL 0.8942
882 DOR 0.8941
883 FA1 0.8941
884 URQ 0.8941
885 6ME 0.8940
886 KBG 0.8940
887 AW5 0.8939
888 0FN 0.8939
889 ICC 0.8939
890 TM4 0.8939
891 JZ4 0.8938
892 KBB 0.8935
893 VAL 0.8935
894 LSA 0.8933
895 CN0 0.8932
896 APY 0.8931
897 HQJ 0.8930
898 DPR 0.8927
899 DNF 0.8927
900 R2B 0.8927
901 PRS 0.8926
902 PAF 0.8925
903 J9N 0.8925
904 K17 0.8925
905 SR1 0.8925
906 1U6 0.8925
907 IJZ 0.8924
908 7VJ 0.8924
909 PIY 0.8923
910 H3M 0.8920
911 Z6J 0.8920
912 E1T 0.8920
913 3BU 0.8920
914 7ZE 0.8918
915 QY9 0.8918
916 SKM 0.8918
917 THE 0.8917
918 PD2 0.8917
919 FBT 0.8917
920 NEQ 0.8916
921 YIO 0.8916
922 25T 0.8914
923 P2D 0.8914
924 3MA 0.8912
925 PYJ 0.8911
926 PIM 0.8909
927 CYS 0.8909
928 TYL 0.8907
929 34D 0.8907
930 FRU 0.8907
931 APG 0.8907
932 FBS 0.8904
933 B24 0.8904
934 MRZ 0.8902
935 PRY 0.8900
936 HXX 0.8899
937 DS0 0.8898
938 PEP 0.8898
939 TBS 0.8895
940 HIU 0.8894
941 3R6 0.8893
942 FUM 0.8893
943 NXA 0.8893
944 QPR 0.8892
945 RBL 0.8890
946 QSH 0.8890
947 GVG 0.8889
948 MFB 0.8888
949 2RH 0.8885
950 23J 0.8885
951 1DH 0.8884
952 FPK 0.8884
953 BCF 0.8884
954 ZZ3 0.8883
955 BDF 0.8882
956 HFB 0.8880
957 MSR 0.8880
958 CFF 0.8878
959 JFJ 0.8878
960 4J8 0.8876
961 6KT 0.8876
962 BBF 0.8876
963 2ZQ 0.8875
964 ICB 0.8873
965 HA7 0.8873
966 D07 0.8871
967 APZ 0.8871
968 4SD 0.8871
969 MBG 0.8871
970 SRO 0.8870
971 FLA 0.8870
972 RPQ 0.8870
973 HX2 0.8870
974 4FH 0.8869
975 BNS 0.8869
976 12B 0.8869
977 1AL 0.8868
978 9FE 0.8868
979 C5J 0.8867
980 9RW 0.8867
981 329 0.8866
982 BR8 0.8866
983 GUA 0.8866
984 6HQ 0.8865
985 GXE 0.8865
986 E60 0.8863
987 X09 0.8860
988 DHS 0.8860
989 3V4 0.8859
990