Receptor
PDB id Resolution Class Description Source Keywords
5MOH 1.38 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF CK2ALPHA WITH ZT0583 BOUND. HOMO SAPIENS CK2ALPHA CK2A FRAGMENT BASED DRUG DISCOVERY HIGH CONCENTRSCREENING SELECTIVE ATP COMPETITIVE INHIBITORS SURFACE ENREDUCTION TRANSFERASE
Ref.: A FRAGMENT-BASED APPROACH LEADING TO THE DISCOVERY NOVEL BINDING SITE AND THE SELECTIVE CK2 INHIBITOR BIOORG. MED. CHEM. V. 25 3471 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT A:402;
A:403;
Invalid;
Invalid;
none;
none;
submit data
59.044 C2 H3 O2 CC(=O...
YTX A:401;
Valid;
none;
submit data
182.173 C9 H10 O4 COc1c...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5H8E 2.15 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF CK2 WITH COMPOUND 7H HOMO SAPIENS KINASE INHIBITOR CK2 TRANSFERASE-TRANSFERASE INHIBITOR CO
Ref.: POTENT AND SELECTIVE CK2 KINASE INHIBITORS WITH EFF WNT PATHWAY SIGNALING IN VIVO. ACS MED.CHEM.LETT. V. 7 300 2016
Members (123)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 133 families.
1 4FBX - 0TJ GLY ASP ASP ASP ASP ASP n/a n/a
2 6L21 - E3U C16 H12 O6 c1cc(c(c2c....
3 5OUU - AWN C22 H20 Cl N3 c1ccc(cc1)....
4 4RLL - E91 C21 H14 N2 O2 c1ccc2c(c1....
5 5CU4 Kd = 0.32 uM 54S C26 H26 Cl N3 O4 c1ccc(cc1)....
6 6HOT - CIY C10 H10 O3 COc1cc(ccc....
7 5ORJ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
8 3MB6 ic50 = 100 nM 01I C16 H8 O6 c1cc2c(cc(....
9 5M4F - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
10 6A1C - 9NX C17 H15 Br N4 O2 S COc1cc(c(c....
11 6EHU - B5E C25 H24 F3 N3 CCc1ccccc1....
12 5CVH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
13 3BQC ic50 ~ 2 uM EMO C15 H10 O5 Cc1cc2c(c(....
14 6L22 - E3U C16 H12 O6 c1cc(c(c2c....
15 5N9K Ki = 0.46 nM 8QK C20 H13 Cl2 N O4 COc1ccc(cc....
16 5OTQ - AUH C25 H27 N3 O CCc1ccccc1....
17 5CU2 - 54G C8 H8 O3 Cc1ccc(c(c....
18 5MO5 - 4IH C17 H21 Cl N2 O2 S CS(=O)(=O)....
19 5M4I - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
20 5MP8 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
21 6HOR - GJK C11 H12 O3 CC(=O)/C=C....
22 5MOV - HC4 C9 H8 O3 c1cc(ccc1C....
23 5MOH - YTX C9 H10 O4 COc1cc(ccc....
24 6JWA ic50 = 10.9 uM 5ID C11 H13 I N4 O4 c1c(c2c(nc....
25 6HNW ic50 = 200 nM CUE C15 H8 O5 c1cc2c(cc1....
26 5CSH Kd = 270 uM 54E C13 H12 Cl N c1ccc(cc1)....
27 7A49 ic50 = 3.26 uM QWN C5 H2 Br Cl N4 c1c2c(nc(c....
28 5OTL - AQT C25 H26 Cl N3 O CCc1ccccc1....
29 5ORK Kd = 234 uM A4T C13 H11 Cl F N c1ccc(c(c1....
30 7A4B ic50 = 2.56 uM QXW C5 H2 Br2 N4 c1c2c(nc(c....
31 3OWL ic50 = 0.67 uM 19E C16 H11 Cl N2 O Cc1cnc(c2c....
32 5OYF - B4Q C25 H27 N3 CCc1ccccc1....
33 5H8G Kd = 48.2 pM 5Y4 C23 H29 N9 O CC(=O)Nc1c....
34 5OS7 - A8Q C16 H19 Cl N CC(C)c1ccc....
35 6YPJ - P5W C16 H12 N2 O2 S c1ccc(cc1)....
36 5OTZ Kd = 6.5 uM AUT C15 H15 Cl2 N CCc1ccccc1....
37 6HOQ - FER C10 H10 O4 COc1cc(ccc....
38 5OUM - AVK C18 H18 Cl N3 c1ccc(cc1)....
39 5B0X ic50 = 0.02 uM HCK C18 H14 N2 O4 S COc1ccc(cc....
40 5MO8 Kd = 1.64 uM C98 C26 H26 Cl N3 O4 c1ccc(cc1)....
41 6RCB ic50 = 0.33 uM JYZ C17 H14 N2 O4 COc1cc(ccc....
42 6HME - FXB C21 H21 N O3 CC(C)n1c2c....
43 6HOP - FER C10 H10 O4 COc1cc(ccc....
44 5OTO - AQW C24 H23 Cl2 N3 CCc1ccccc1....
45 3AT4 Kd = 2.26 nM CCK C20 H20 N6 O2 CC(C)Nc1cc....
46 3OWJ Ki = 0.86 uM 1EL C17 H14 N2 O2 Cc1c2c(c(c....
47 6RFF ic50 = 0.37 uM K1B C12 H6 Br N5 O4 S c1cc(c(cc1....
48 6EII - B5W C22 H23 Cl N c1ccc(cc1)....
49 5CU0 - 54R C18 H21 Cl N2 O CC(=O)NCCC....
50 5H8E Kd = 6.33 pM 5Y3 C21 H25 N9 O CC(=O)Nc1c....
51 5OWH - B0K C10 H9 Br4 N3 c1nc2c(n1C....
52 6L1Z - E3U C16 H12 O6 c1cc(c(c2c....
53 3WAR - NIO C6 H5 N O2 c1cc(cnc1)....
54 5MOE Kd = 520 uM OQC C11 H10 Cl N O c1cc(c(cc1....
55 5OUE - AVZ C18 H19 Cl N3 c1ccc(cc1)....
56 5MOD Kd = 300 uM 86L C10 H14 Cl N O CC(C)Oc1cc....
57 6RB1 ic50 = 1.37 uM JWQ C14 H9 F3 N4 O3 S COc1cc(ccc....
58 6TEI - N4N C15 H11 N3 O2 S c1ccnc(c1)....
59 5OWL - B0K C10 H9 Br4 N3 c1nc2c(n1C....
60 6HBN - FXB C21 H21 N O3 CC(C)n1c2c....
61 5CU3 Kd = 0.32 uM 54S C26 H26 Cl N3 O4 c1ccc(cc1)....
62 5OTR - AU8 C13 H12 Cl2 N c1ccc(cc1)....
63 4KWP Ki = 0.04 uM EXX C12 H10 Br4 N2 O3 c1nc2c(n1[....
64 5OSL - A9K C13 H12 Cl N O c1ccc(c(c1....
65 5N9N Ki = 0.41 nM KC5 C20 H15 Cl2 N O4 COc1ccc(cc....
66 5CSP Kd = 58 uM 54G C8 H8 O3 Cc1ccc(c(c....
67 5CTP - 54R C18 H21 Cl N2 O CC(=O)NCCC....
68 5MOW - BR9 C5 H6 Br N3 c1c(cnc(c1....
69 4UB7 Ki = 2.5 nM 3G5 C16 H8 Br2 O5 c1cc(ccc1C....
70 5MMF - JMB C16 H19 Cl N CCC[NH2+]C....
71 5OTH - AQ8 C25 H26 Cl N3 O CCc1ccccc1....
72 1PJK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
73 6YPK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
74 3NSZ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
75 5OTI - AOK C25 H26 Cl N3 CCc1ccccc1....
76 3AXW - TID C9 H7 N3 O2 S c1cc(ccc1c....
77 5MO6 - KXZ C19 H21 Cl N2 O3 c1ccc(cc1)....
78 2PVR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
79 3C13 - EMO C15 H10 O5 Cc1cc2c(c(....
80 5CS6 Kd = 630 uM K82 C10 H14 Cl N O CCCOc1ccc(....
81 6YPH - N5Q C20 H14 N2 O3 S c1ccc2cc(c....
82 3PE2 Ki = 0.175 nM E1B C20 H12 N4 O2 C#Cc1cccc(....
83 5CT0 - 54P C16 H18 Cl N O c1ccc(cc1)....
84 6RCM ic50 = 0.36 uM K0N C17 H18 N4 O3 S CC(C)(C)c1....
85 5CU6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
86 5M4C - 7EY C16 H14 N2 O2 S2 Cc1ccc(cc1....
87 6SPX ic50 = 44 uM DAS ASP ASP ASP ASP ASP LYS 9AB n/a n/a
88 5MO7 - YRA C16 H17 Cl N2 O c1ccc(cc1)....
89 5N9L Ki = 15 nM 8QH C20 H15 Cl2 N O3 Cc1ccc(cc1....
90 5OT5 - AWK C25 H26 Cl N3 CCc1ccccc1....
91 3OWK ic50 = 1.5 uM 18E C16 H11 Cl N2 O Cc1cnc(c2c....
92 5MMR - H83 C17 H21 Cl N2 c1ccc(cc1)....
93 5MPJ - J2P C15 H17 Cl N CC[NH2+]Cc....
94 5OQU - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
95 6GIH - EZN C15 H13 Cl N2 c1cc(c2cc[....
96 6RFE ic50 = 0.28 uM K0Z C13 H9 Br N4 O3 S COc1cc(ccc....
97 6YPG - N5Q C20 H14 N2 O3 S c1ccc2cc(c....
98 5CSV - GAB C7 H7 N O2 c1cc(cc(c1....
99 5MOT - HBD C7 H7 N O2 c1cc(ccc1C....
100 3R0T ic50 = 0.91 nM FU9 C22 H16 F3 N5 O2 c1cc(cc(c1....
101 3PE1 Ki = 0.223 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
102 3JUH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
103 5CLP - 42J C8 H9 Cl2 N c1cc(c(cc1....
104 5ORH Kd = 41 uM A4N C14 H14 Cl N Cc1ccccc1c....
105 3H30 Ki = 29.2 uM RFZ C12 H12 Cl2 N2 O4 c1c2c(cc(c....
106 2ZJW Ki = 0.02 uM REF C14 H6 O8 c1c2c-3c(c....
107 6HOU - V55 C8 H8 O3 COc1cc(ccc....
108 7A4C ic50 = 3.82 uM QWW C5 H Br3 N4 c12c(c(c(n....
109 6YPN - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
110 5OSZ - AHK C24 H25 Cl N3 CCc1ccccc1....
111 4GRB ic50 = 17 nM 0XG C19 H18 N4 O4 S CN(C)C(=O)....
112 5OT6 - AJK C19 H20 Cl N2 c1ccc(cc1)....
113 6EHK - AUW C24 H23 Cl2 N3 CCc1ccccc1....
114 6L24 - E3U C16 H12 O6 c1cc(c(c2c....
115 3MB7 ic50 = 200 nM 14I C16 H8 O6 c1cc2c(cc(....
116 5OS8 - J27 C14 H14 Cl F N Cc1cc(ccc1....
117 5OTY - AUW C24 H23 Cl2 N3 CCc1ccccc1....
118 5OTD - AOW C24 H24 Cl N4 O2 CCc1ccccc1....
119 6GMD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
120 5CVF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
121 6HNY - GHT C19 H19 N O4 CN1CCc2cc(....
122 5CX9 - 551 C20 H23 Cl N2 O3 COC(=O)CC(....
123 5OUL - AWE C13 H11 Cl F N c1cc(cc(c1....
70% Homology Family (183)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 101 families.
1 4FBX - 0TJ GLY ASP ASP ASP ASP ASP n/a n/a
2 6L21 - E3U C16 H12 O6 c1cc(c(c2c....
3 5OUU - AWN C22 H20 Cl N3 c1ccc(cc1)....
4 4RLL - E91 C21 H14 N2 O2 c1ccc2c(c1....
5 5CU4 Kd = 0.32 uM 54S C26 H26 Cl N3 O4 c1ccc(cc1)....
6 6HOT - CIY C10 H10 O3 COc1cc(ccc....
7 5ORJ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
8 3MB6 ic50 = 100 nM 01I C16 H8 O6 c1cc2c(cc(....
9 5M4F - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
10 6A1C - 9NX C17 H15 Br N4 O2 S COc1cc(c(c....
11 6EHU - B5E C25 H24 F3 N3 CCc1ccccc1....
12 5CVH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
13 3BQC ic50 ~ 2 uM EMO C15 H10 O5 Cc1cc2c(c(....
14 6L22 - E3U C16 H12 O6 c1cc(c(c2c....
15 5N9K Ki = 0.46 nM 8QK C20 H13 Cl2 N O4 COc1ccc(cc....
16 5OTQ - AUH C25 H27 N3 O CCc1ccccc1....
17 5CU2 - 54G C8 H8 O3 Cc1ccc(c(c....
18 5MO5 - 4IH C17 H21 Cl N2 O2 S CS(=O)(=O)....
19 5M4I - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
20 5MP8 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
21 6HOR - GJK C11 H12 O3 CC(=O)/C=C....
22 5MOV - HC4 C9 H8 O3 c1cc(ccc1C....
23 5MOH - YTX C9 H10 O4 COc1cc(ccc....
24 6JWA ic50 = 10.9 uM 5ID C11 H13 I N4 O4 c1c(c2c(nc....
25 6HNW ic50 = 200 nM CUE C15 H8 O5 c1cc2c(cc1....
26 5CSH Kd = 270 uM 54E C13 H12 Cl N c1ccc(cc1)....
27 7A49 ic50 = 3.26 uM QWN C5 H2 Br Cl N4 c1c2c(nc(c....
28 5OTL - AQT C25 H26 Cl N3 O CCc1ccccc1....
29 5ORK Kd = 234 uM A4T C13 H11 Cl F N c1ccc(c(c1....
30 7A4B ic50 = 2.56 uM QXW C5 H2 Br2 N4 c1c2c(nc(c....
31 3OWL ic50 = 0.67 uM 19E C16 H11 Cl N2 O Cc1cnc(c2c....
32 5OYF - B4Q C25 H27 N3 CCc1ccccc1....
33 5H8G Kd = 48.2 pM 5Y4 C23 H29 N9 O CC(=O)Nc1c....
34 5OS7 - A8Q C16 H19 Cl N CC(C)c1ccc....
35 6YPJ - P5W C16 H12 N2 O2 S c1ccc(cc1)....
36 5OTZ Kd = 6.5 uM AUT C15 H15 Cl2 N CCc1ccccc1....
37 6HOQ - FER C10 H10 O4 COc1cc(ccc....
38 5OUM - AVK C18 H18 Cl N3 c1ccc(cc1)....
39 5B0X ic50 = 0.02 uM HCK C18 H14 N2 O4 S COc1ccc(cc....
40 5MO8 Kd = 1.64 uM C98 C26 H26 Cl N3 O4 c1ccc(cc1)....
41 6RCB ic50 = 0.33 uM JYZ C17 H14 N2 O4 COc1cc(ccc....
42 6HME - FXB C21 H21 N O3 CC(C)n1c2c....
43 6HOP - FER C10 H10 O4 COc1cc(ccc....
44 5OTO - AQW C24 H23 Cl2 N3 CCc1ccccc1....
45 3AT4 Kd = 2.26 nM CCK C20 H20 N6 O2 CC(C)Nc1cc....
46 3OWJ Ki = 0.86 uM 1EL C17 H14 N2 O2 Cc1c2c(c(c....
47 6RFF ic50 = 0.37 uM K1B C12 H6 Br N5 O4 S c1cc(c(cc1....
48 6EII - B5W C22 H23 Cl N c1ccc(cc1)....
49 5CU0 - 54R C18 H21 Cl N2 O CC(=O)NCCC....
50 5H8E Kd = 6.33 pM 5Y3 C21 H25 N9 O CC(=O)Nc1c....
51 5OWH - B0K C10 H9 Br4 N3 c1nc2c(n1C....
52 6L1Z - E3U C16 H12 O6 c1cc(c(c2c....
53 3WAR - NIO C6 H5 N O2 c1cc(cnc1)....
54 5MOE Kd = 520 uM OQC C11 H10 Cl N O c1cc(c(cc1....
55 5OUE - AVZ C18 H19 Cl N3 c1ccc(cc1)....
56 5MOD Kd = 300 uM 86L C10 H14 Cl N O CC(C)Oc1cc....
57 6RB1 ic50 = 1.37 uM JWQ C14 H9 F3 N4 O3 S COc1cc(ccc....
58 6TEI - N4N C15 H11 N3 O2 S c1ccnc(c1)....
59 5OWL - B0K C10 H9 Br4 N3 c1nc2c(n1C....
60 6HBN - FXB C21 H21 N O3 CC(C)n1c2c....
61 5CU3 Kd = 0.32 uM 54S C26 H26 Cl N3 O4 c1ccc(cc1)....
62 5OTR - AU8 C13 H12 Cl2 N c1ccc(cc1)....
63 4KWP Ki = 0.04 uM EXX C12 H10 Br4 N2 O3 c1nc2c(n1[....
64 5OSL - A9K C13 H12 Cl N O c1ccc(c(c1....
65 5N9N Ki = 0.41 nM KC5 C20 H15 Cl2 N O4 COc1ccc(cc....
66 5CSP Kd = 58 uM 54G C8 H8 O3 Cc1ccc(c(c....
67 5CTP - 54R C18 H21 Cl N2 O CC(=O)NCCC....
68 5MOW - BR9 C5 H6 Br N3 c1c(cnc(c1....
69 4UB7 Ki = 2.5 nM 3G5 C16 H8 Br2 O5 c1cc(ccc1C....
70 5MMF - JMB C16 H19 Cl N CCC[NH2+]C....
71 5OTH - AQ8 C25 H26 Cl N3 O CCc1ccccc1....
72 1PJK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
73 6YPK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
74 3NSZ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
75 5OTI - AOK C25 H26 Cl N3 CCc1ccccc1....
76 3AXW - TID C9 H7 N3 O2 S c1cc(ccc1c....
77 5MO6 - KXZ C19 H21 Cl N2 O3 c1ccc(cc1)....
78 2PVR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
79 3C13 - EMO C15 H10 O5 Cc1cc2c(c(....
80 5CS6 Kd = 630 uM K82 C10 H14 Cl N O CCCOc1ccc(....
81 6YPH - N5Q C20 H14 N2 O3 S c1ccc2cc(c....
82 3PE2 Ki = 0.175 nM E1B C20 H12 N4 O2 C#Cc1cccc(....
83 5CT0 - 54P C16 H18 Cl N O c1ccc(cc1)....
84 6RCM ic50 = 0.36 uM K0N C17 H18 N4 O3 S CC(C)(C)c1....
85 5CU6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
86 5M4C - 7EY C16 H14 N2 O2 S2 Cc1ccc(cc1....
87 6SPX ic50 = 44 uM DAS ASP ASP ASP ASP ASP LYS 9AB n/a n/a
88 5MO7 - YRA C16 H17 Cl N2 O c1ccc(cc1)....
89 5N9L Ki = 15 nM 8QH C20 H15 Cl2 N O3 Cc1ccc(cc1....
90 5OT5 - AWK C25 H26 Cl N3 CCc1ccccc1....
91 3OWK ic50 = 1.5 uM 18E C16 H11 Cl N2 O Cc1cnc(c2c....
92 5MMR - H83 C17 H21 Cl N2 c1ccc(cc1)....
93 5MPJ - J2P C15 H17 Cl N CC[NH2+]Cc....
94 5OQU - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
95 6GIH - EZN C15 H13 Cl N2 c1cc(c2cc[....
96 6RFE ic50 = 0.28 uM K0Z C13 H9 Br N4 O3 S COc1cc(ccc....
97 6YPG - N5Q C20 H14 N2 O3 S c1ccc2cc(c....
98 5CSV - GAB C7 H7 N O2 c1cc(cc(c1....
99 5MOT - HBD C7 H7 N O2 c1cc(ccc1C....
100 3R0T ic50 = 0.91 nM FU9 C22 H16 F3 N5 O2 c1cc(cc(c1....
101 3PE1 Ki = 0.223 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
102 3JUH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
103 5CLP - 42J C8 H9 Cl2 N c1cc(c(cc1....
104 5ORH Kd = 41 uM A4N C14 H14 Cl N Cc1ccccc1c....
105 3H30 Ki = 29.2 uM RFZ C12 H12 Cl2 N2 O4 c1c2c(cc(c....
106 2ZJW Ki = 0.02 uM REF C14 H6 O8 c1c2c-3c(c....
107 6HOU - V55 C8 H8 O3 COc1cc(ccc....
108 7A4C ic50 = 3.82 uM QWW C5 H Br3 N4 c12c(c(c(n....
109 6YPN - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
110 5OSZ - AHK C24 H25 Cl N3 CCc1ccccc1....
111 4GRB ic50 = 17 nM 0XG C19 H18 N4 O4 S CN(C)C(=O)....
112 5OT6 - AJK C19 H20 Cl N2 c1ccc(cc1)....
113 6EHK - AUW C24 H23 Cl2 N3 CCc1ccccc1....
114 6L24 - E3U C16 H12 O6 c1cc(c(c2c....
115 3MB7 ic50 = 200 nM 14I C16 H8 O6 c1cc2c(cc(....
116 5OS8 - J27 C14 H14 Cl F N Cc1cc(ccc1....
117 5OTY - AUW C24 H23 Cl2 N3 CCc1ccccc1....
118 5OTD - AOW C24 H24 Cl N4 O2 CCc1ccccc1....
119 6GMD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
120 5CVF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
121 6HNY - GHT C19 H19 N O4 CN1CCc2cc(....
122 5CX9 - 551 C20 H23 Cl N2 O3 COC(=O)CC(....
123 5OUL - AWE C13 H11 Cl F N c1cc(cc(c1....
124 6TEW - N5Q C20 H14 N2 O3 S c1ccc2cc(c....
125 5Y9M - NIO C6 H5 N O2 c1cc(cnc1)....
126 7A1B ic50 = 2.36 uM QXW C5 H2 Br2 N4 c1c2c(nc(c....
127 7A2H - QX2 C6 H2 Br3 N3 c1[nH]c2c(....
128 5M56 - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
129 5M4U - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
130 6HMD - GDW C21 H24 N2 O2 CCN(CC)CCn....
131 6HMQ - 4B0 C9 H7 Br4 N3 O C(Cn1c2c(c....
132 5OOI - 9YE C23 H25 N O3 CC(C)n1c2c....
133 7A1Z ic50 = 3.38 uM QWN C5 H2 Br Cl N4 c1c2c(nc(c....
134 6TE2 - N4N C15 H11 N3 O2 S c1ccnc(c1)....
135 6HMB - 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
136 7A22 ic50 = 1.98 uM QWW C5 H Br3 N4 c12c(c(c(n....
137 3OFM - 4B0 C9 H7 Br4 N3 O C(Cn1c2c(c....
138 6HMC - FXB C21 H21 N O3 CC(C)n1c2c....
139 5YF9 - NIO C6 H5 N O2 c1cc(cnc1)....
140 6TGU - N92 C16 H11 Cl N2 O3 S c1cc(ccc1c....
141 2PVH Ki = 0.26 uM P19 C17 H14 N6 c1ccc(cc1)....
142 1M2P - HNA C14 H7 N O6 c1cc2c(c(c....
143 1LPU - BEN C7 H8 N2 [H]/N=C(c1....
144 2QC6 ic50 = 0.1 uM G12 C10 H6 Br2 O3 CC1=C(C(=O....
145 4ANM ic50 = 28 nM WUL C15 H14 Br N3 O3 c1cc2c(cc1....
146 1DAW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
147 4RLK - E91 C21 H14 N2 O2 c1ccc2c(c1....
148 2OXD - K32 C7 H2 Br4 N2 O c12c(c(c(c....
149 2PVM Ki = 0.36 uM P29 C17 H15 N9 c1ccc(cc1)....
150 1J91 - TBS C6 H Br4 N3 c12c(c(c(c....
151 3FL5 - TXQ C14 H8 O6 c1cc(c(c2c....
152 3PWD Ki = 0.22 uM CZ0 C14 H9 N O5 CC1=CC(=O)....
153 3KXH - K66 C11 H9 Br4 N3 O2 CN(C)c1nc2....
154 4DGM ic50 = 1.2 uM AGI C15 H10 O5 c1cc(ccc1C....
155 3PVG - K68 C9 H4 Br4 N2 O2 c1nc2c(n1C....
156 1ZOG Ki = 0.07 uM K37 C8 H4 Br4 N2 S CSc1[nH]c2....
157 2PVJ Ki = 0.005 uM P44 C19 H21 N7 c1ccc(cc1)....
158 4DGN ic50 = 0.35 uM LU2 C15 H10 O6 c1cc(c(cc1....
159 1M2Q - MNX C13 H7 N O6 c1cc(c2c(c....
160 2OXY - K17 C7 H2 Br4 N2 c1[nH]c2c(....
161 1M2R - MNY C14 H10 N2 O4 c1cc(c2c(c....
162 3KXN - K8X C7 H2 I4 N2 c1[nH]c2c(....
163 6QS5 ic50 = 0.57 uM JGB C10 H8 N2 O3 c1cc(c(cc1....
164 1ZOE Ki = 0.04 uM K25 C9 H7 Br4 N3 CN(C)c1[nH....
165 2PVL Ki = 0.024 uM P55 C18 H20 N8 CCN1CCN(CC....
166 1LP4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
167 2PVN Ki = 0.00035 uM P63 C20 H16 N8 O CC(=O)Nc1c....
168 3KXG - K6X C7 H Br5 N2 c12c(c(c(c....
169 3BE9 Ki = 24 nM P04 C19 H21 N7 O c1cc2cc(c1....
170 2OXX - K22 C7 H2 Br4 N2 S c12c(c(c(c....
171 3KXM - K74 C11 H9 Br4 N3 O S CNC(=O)CSc....
172 1LR4 - BEN C7 H8 N2 [H]/N=C(c1....
173 1OM1 Ki = 0.17 uM IQA C17 H12 N2 O3 c1ccc2c(c1....
174 1ZOH Ki = 0.1 uM K44 C10 H7 Br4 N3 C[N@@]1CCn....
175 2PVK Ki = 0.008 uM P45 C19 H14 Cl N7 c1ccc(cc1)....
176 1DAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
177 6KO6 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
178 6K3L Kd = 60.1 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
179 6ISJ - 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
180 5OMY - 9YE C23 H25 N O3 CC(C)n1c2c....
181 6SPW ic50 = 4.5 uM DAS ASP ASP ASP ASP ASP LYS A0Z n/a n/a
182 5ONI - 9YE C23 H25 N O3 CC(C)n1c2c....
183 6XX7 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (232)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 5R8X - SLY C13 H13 N O c1ccc(cc1)....
2 3GCV Kd = 74 nM SS6 C29 H30 N8 O Cc1cccc(c1....
3 3L8S Kd = 99 nM BFF C20 H24 Br F2 N5 O3 S c1c(cc(c(c....
4 6Y7Y - OFQ C11 H19 N O C1C2CC3CC1....
5 3RIN ic50 = 1.3 nM I2O C23 H24 N2 O2 Cc1ccc(cc1....
6 5N65 - 8OT C20 H18 N4 S c1ccc(cc1)....
7 4FA2 - SB0 C20 H21 F N4 O2 COc1nccc(n....
8 5R9B - JGM C11 H15 N3 O3 CC(=O)N[C@....
9 2GHM - LIC C24 H28 Cl N5 O3 C[C@@H](C(....
10 5RA0 - JFS C14 H12 N2 O c1ccc2c(c1....
11 1W84 ic50 = 35 uM L12 C15 H14 N2 c1ccc2c(c1....
12 6M95 ic50 = 140 nM J8S C21 H25 N O2 S COc1cc(ccc....
13 4EH5 - IRG C17 H16 N4 c1ccc(cc1)....
14 5R9K - SR4 C11 H10 O3 c1ccc2c(c1....
15 2BAK Kd = 37 nM AQZ C32 H37 N7 O4 Cc1ccc(cc1....
16 3HV6 ic50 = 5500 nM R39 C27 H35 N5 O3 Cc1ccc(cc1....
17 5R9G - RGY C12 H17 N3 O2 Cc1c2c(on1....
18 3HP2 - P36 C19 H16 Br N O2 c1ccc(cc1)....
19 6M9L ic50 = 29 nM J9G C19 H14 F2 N4 O c1ccc(cc1)....
20 6YCU - OKZ C13 H14 N2 O4 S CCCNS(=O)(....
21 1WBO ic50 > 1 mM 2CH C6 H5 Cl O c1ccc(c(c1....
22 4KIQ ic50 = 23 nM 1RA C23 H23 N3 O4 CCOC(=O)n1....
23 3GC7 ic50 = 0.4 nM B45 C28 H27 Cl3 F N3 O CC(C)N1CCC....
24 4EH6 - IRG C17 H16 N4 c1ccc(cc1)....
25 5MTX Kd = 17.7 nM FJI C34 H31 F N4 O5 c1ccc(cc1)....
26 2ZB0 Ki = 0.24 uM GK3 C24 H18 N4 O2 Cc1ccc(cc1....
27 2GTM ic50 = 542 nM LID C19 H15 Cl F2 N6 CCn1c2c(cn....
28 5N66 - B96 C31 H37 N5 O3 Cc1ccc(cc1....
29 6Y81 Kd = 25.1 uM OG5 C29 H35 N5 O5 S c1ccc(cc1)....
30 5R94 - SOV C12 H8 N2 O2 Cc1ccc(cc1....
31 2YIX Kd = 3.3 nM YIX C19 H23 N5 O S CCNC(=O)NC....
32 3OCG ic50 = 3 nM OCG C21 H18 N6 O3 Cc1ccc(cc1....
33 1BL7 - SB4 C18 H19 F N6 c1cc(ccc1c....
34 5R99 - SU7 C15 H18 N2 O c1ccc(cc1)....
35 6YJC ic50 = 81.3 nM OSZ C32 H41 N7 O3 c1ccc(cc1)....
36 3P7C ic50 = 0.022 uM P7C C25 H33 Cl2 N5 O3 S CC(C)(C)c1....
37 5RA2 - SV4 C11 H17 N3 Cc1cccnc1N....
38 5R90 - SNJ C15 H12 N2 O c1ccc(cc1)....
39 6Y6V - OE5 C32 H33 N7 O2 Cc1ccc(cc1....
40 5TBE Kd = 4.4 nM 78L C33 H30 F2 N4 O4 S c1cc(sc1)C....
41 4KIP ic50 = 7 nM 1R9 C21 H18 Cl N3 O2 S Cc1ccc(cc1....
42 5R8Y - SMV C5 H5 N S2 c1cc(sc1)C....
43 2EWA - SB2 C21 H16 F N3 O S C[S@](=O)c....
44 2GHL - LIB C23 H26 Cl N5 O3 C[C@@H](C(....
45 1ZZ2 ic50 = 6 uM B11 C24 H26 F N3 O4 S c1ccc(c(c1....
46 5R9H - SQV C10 H13 N O3 C[C@@H](c1....
47 3ZSI - 52P C19 H9 Cl2 F2 N3 O S c1cc(c(c(c....
48 2YIW - YIW C30 H33 N7 O S CC(C)c1nnc....
49 5WJJ ic50 = 5.4 nM AQY C25 H19 F N6 O2 Cc1cc(ccc1....
50 1A9U - SB2 C21 H16 F N3 O S C[S@](=O)c....
51 6ZWP ic50 = 22.1 nM OE8 C34 H37 F N6 O3 c1ccc(cc1)....
52 1M7Q ic50 = 2.6 nM DQO C24 H20 Cl2 F2 N4 O c1cc(c(c(c....
53 5R91 - SNV C12 H19 N3 O c1ccc(c(c1....
54 5MTY Kd = 1.3 nM HB9 C29 H23 F2 N3 O4 S c1cc(sc1)C....
55 6HWU ic50 = 54.7 nM GE5 C31 H26 F N5 O3 S COc1ccc(c(....
56 4EH7 - IRG C17 H16 N4 c1ccc(cc1)....
57 1YQJ Ki = 7.3 nM 6NP C30 H27 N5 c1ccc(cc1)....
58 4EH3 - NAR C15 H12 O5 c1cc(ccc1[....
59 5R9I - SQY C15 H14 Br N O2 COC(=O)[C@....
60 4AA5 ic50 = 16 nM NQB C24 H27 N5 O2 Cc1ccc(cc1....
61 1OVE ic50 = 0.74 nM 358 C26 H22 Cl2 F2 N2 O c1cc(c(c(c....
62 3UVP ic50 = 0.035 uM 048 C24 H21 F N2 O2 c1ccc(cc1)....
63 5N67 - 8ON C28 H30 N6 O CC(=O)N1CC....
64 3NNV ic50 = 27 nM 437 C25 H26 N4 O2 CC(C)(C)c1....
65 3CTQ ic50 = 40 nM 337 C30 H34 N6 O5 S Cc1ccc(cc1....
66 5R9T - 6T5 C13 H16 N4 O CC1=NNC(=O....
67 5R96 - SQ7 C9 H5 Cl N2 O2 c1cc(ccc1N....
68 3IW7 - IPK C26 H26 N4 O S c1ccc(cc1)....
69 3ITZ ic50 = 1.4 nM P66 C21 H15 Cl F2 N6 O c1cc(c(c(c....
70 2ZB1 Ki = 0.48 uM GK4 C21 H21 N3 O2 Cc1ccc(cc1....
71 3HV5 ic50 = 150 nM R24 C30 H29 N7 O3 Cc1ccc(cc1....
72 1WBW ic50 = 44 uM LI4 C16 H14 N2 O c1ccc2c(c1....
73 3P79 ic50 = 2.3 uM P79 C24 H29 N5 O4 S CC(C)(C)c1....
74 3HV7 Kd ~ 12 nM 1AU C24 H25 N5 O CC(C)(C)c1....
75 3GFE ic50 = 3.2 nM P37 C24 H21 F2 N5 O2 Cc1ccc(cc1....
76 3ZYA - 2A8 C21 H18 N2 O c1ccc2c(c1....
77 2RG5 ic50 = 3.1 nM 279 C19 H22 N6 O3 CCNC(=O)c1....
78 3L8X ic50 = 10 nM N4D C20 H18 N6 O Cc1ccc(cc1....
79 5R9A - SQM C12 H12 N4 O2 Cn1c(c(cn1....
80 5R9S - A9B C11 H9 Cl N2 O2 c1cc(ccc1c....
81 5OMH - 9Y5 C16 H12 Cl N3 O2 S Cc1c2c(n(n....
82 5R8W - JND C8 H8 N2 O S CCc1cc2c(s....
83 5RA6 - SVM C15 H21 N3 S c1ccnc(c1)....
84 3GCS Kd = 56 nM BAX C21 H16 Cl F3 N4 O3 CNC(=O)c1c....
85 6OHD ic50 = 0.42 nM MKP C21 H21 N5 O3 Cc1ccc(cc1....
86 3ZS5 - SB2 C21 H16 F N3 O S C[S@](=O)c....
87 3D83 Ki = 4.4 nM GK6 C28 H30 N4 O3 Cc1ccc(cc1....
88 1YW2 ic50 = 141 nM PGJ C22 H18 F N3 O5 CCOC[N@]1C....
89 1W82 ic50 = 196 nM L10 C20 H21 Cl N4 O CC(C)(C)C1....
90 3ZSG - T75 C24 H21 N3 O S CCc1nc(c(s....
91 5TCO Kd = 3.14 nM 79Q C35 H33 F N4 O4 c1ccc(cc1)....
92 5R9Z - AYS C13 H11 Cl N2 O c1ccc(c(c1....
93 6HWT - GXH C31 H28 F N5 O3 S COc1ccc(c(....
94 4EH8 - IRG C17 H16 N4 c1ccc(cc1)....
95 5R8V - SLV C11 H15 N O2 CCCc1ccc(c....
96 5RA4 - SVG C14 H13 Cl N2 C/C(=NCc1c....
97 3GCP Kd = 15 nM SB2 C21 H16 F N3 O S C[S@](=O)c....
98 3HLL Ki = 0.0058 uM I45 C22 H19 Br F2 N2 O3 Cc1ccc(cc1....
99 1ZZL ic50 = 5 nM TZY C18 H15 F N4 O CC(C)c1nnc....
100 2RG6 ic50 = 2.2 nM 287 C25 H26 N6 O3 Cc1ccc(cc1....
101 6Y80 - SB4 C18 H19 F N6 c1cc(ccc1c....
102 3MPT ic50 = 0.25 uM 1GK C18 H16 N2 O3 Cc1ccccc1C....
103 5OMG - 9Y8 C16 H12 F N3 O2 S CN1c2c([nH....
104 1BL6 - SB6 C18 H16 F N3 c1cc(ccc1c....
105 3NNW ic50 = 9 nM EDD C22 H23 Cl2 N5 O2 CC(C)(C)C1....
106 3GI3 Kd < 1.8 nM B10 C33 H39 N5 O5 S CC(C)(C)c1....
107 3K3J - I46 C14 H9 F2 N3 c1cc(ccc1c....
108 3HEC Kd = 34 uM STI C29 H31 N7 O Cc1ccc(cc1....
109 1IAN - D13 C21 H16 I N3 O S C[S@@](=O)....
110 3FC1 - 52P C19 H9 Cl2 F2 N3 O S c1cc(c(c(c....
111 3MVM ic50 = 3.9 nM 39P C22 H23 N7 O3 CCCNC(=O)c....
112 3NNU ic50 = 48 nM EDB C22 H17 Cl2 N5 O2 S c1cc(cc(c1....
113 1W7H ic50 > 1 mM 3IP C12 H12 N2 O c1ccc(cc1)....
114 5R9X - NZ4 C13 H16 N2 O3 CC(=O)c1cc....
115 3U8W ic50 = 1 nM 09J C24 H21 Cl F N5 O2 CCN1C(=O)C....
116 1WBS ic50 = 0.63 uM LI2 C26 H25 F N4 O2 c1cc2c(cc1....
117 5R9M - A7K C13 H21 N2 O c1ccc(c(c1....
118 4E6C Kd ~ 15 uM 0O8 C25 H53 N O4 P CCCCCCCCCC....
119 5N68 - 8OK C26 H27 N5 O c1ccc(cc1)....
120 1WBV ic50 = 162 uM LI3 C19 H18 F N3 O2 c1cc2c(cc[....
121 5RA3 - SVD C8 H16 N2 O2 CC(C)(C)[C....
122 5MOV - HC4 C9 H8 O3 c1cc(ccc1C....
123 5MOH - YTX C9 H10 O4 COc1cc(ccc....
124 6JWA ic50 = 10.9 uM 5ID C11 H13 I N4 O4 c1c(c2c(nc....
125 6HNW ic50 = 200 nM CUE C15 H8 O5 c1cc2c(cc1....
126 5CSH Kd = 270 uM 54E C13 H12 Cl N c1ccc(cc1)....
127 7A49 ic50 = 3.26 uM QWN C5 H2 Br Cl N4 c1c2c(nc(c....
128 5OTL - AQT C25 H26 Cl N3 O CCc1ccccc1....
129 5ORK Kd = 234 uM A4T C13 H11 Cl F N c1ccc(c(c1....
130 7A4B ic50 = 2.56 uM QXW C5 H2 Br2 N4 c1c2c(nc(c....
131 6GDM - F3Z C33 H33 N9 O2 c1cnc(nc1)....
132 4XP3 - DX4 C5 H5 N5 S c1[nH]c2c(....
133 6QAQ - HVQ C5 H8 N S c1cscc1C[N....
134 4O6E ic50 = 1 nM 2SH C21 H25 Cl F N5 O3 c1cc(c(cc1....
135 5NHJ ic50 = 0.00539 uM 8XE C18 H21 N7 O2 Cn1c(ccn1)....
136 4QYY Kd = 0.05 uM 3G7 C25 H29 Cl N4 O4 CC(=O)c1cc....
137 6QAG - HUH C2 H3 N3 c1cnn[nH]1
138 4I5H Ki < 2 nM G17 C26 H21 F3 N4 O Cc1ccc(cc1....
139 6G93 ic50 = 11 nM EU2 C17 H17 Cl N4 O2 c1cc2c(cc1....
140 4QTE Kd = 0.084 uM 390 C24 H20 Cl2 F N5 O2 Cc1cnc(nc1....
141 4XNE - TT4 C8 H9 N5 c1ccc(cc1)....
142 3QYW - 6PB C11 H8 Br N5 c1cc(cc(c1....
143 5BUE ic50 = 0.003 uM 4V8 C23 H21 N5 O c1ccc(cc1)....
144 6GE0 ic50 = 2.1 nM EVQ C28 H30 Cl N5 O4 C[C@H](c1c....
145 6G9N ic50 = 3 nM ESN C29 H32 Cl N5 O4 Cc1cccc(c1....
146 2Z7L - S91 C20 H19 N5 O3 Cc1cccc(c1....
147 6QAW - HVE C12 H18 N5 c1c[nH]c2c....
148 4ZXT - CAQ C6 H6 O2 c1ccc(c(c1....
149 1WZY ic50 = 0.56 uM F29 C21 H17 N7 C=CCn1c2c(....
150 6DMG - EK6 C27 H26 Cl2 F N5 O4 CCOC(=O)CN....
151 5NHH ic50 < 0.00113 uM 8XH C19 H25 N5 O3 COCCN1CCc2....
152 6OPH - 6QB C21 H18 Cl F N6 O2 Cn1c(ccn1)....
153 6G9H ic50 = 4 nM ERW C24 H30 Cl N5 O3 CC(C)(C)N(....
154 4N4S - 2H1 C25 H24 N6 O Cc1cc(cc2c....
155 4QP8 ic50 = 0.28 uM 362 C14 H10 N6 c1cc(cnc1)....
156 6SLG Kd = 0.000000064 M LHZ C24 H24 F2 N8 O2 Cc1cnc(nc1....
157 4QP4 - 36O C11 H15 N5 c1[nH]c2c(....
158 6G9D ic50 = 4.3 nM ER8 C23 H28 Cl N5 O3 CC(C)(C)NC....
159 6GJB ic50 = 0.008 uM F0H C35 H34 Cl F N6 O4 c1cc(c(cc1....
160 6G91 ic50 = 3200 nM EQW C9 H12 Cl N3 O c1c(cnc(n1....
161 6G8X - EQT C7 H6 Cl N3 c1cc2c(c(c....
162 6DCG ic50 = 7 nM G67 C37 H41 N9 O3 S CC(C)Oc1cc....
163 4QP9 ic50 = 0.071 uM 35X C17 H16 N6 CCCn1cc(cn....
164 5BVE ic50 = 0.01 nM 4VG C25 H28 Cl N5 O3 c1cc(cc(c1....
165 6Q7S - IPH C6 H6 O c1ccc(cc1)....
166 5KE0 - 6S9 C20 H18 N6 O Cc1cc(ccn1....
167 6CPW ic50 = 5.6 nM F8V C35 H35 F N8 O2 S CS[C@]1(CC....
168 4XOY - DX4 C5 H5 N5 S c1[nH]c2c(....
169 6G9K - ESK C27 H28 Cl N5 O4 c1ccc(cc1)....
170 3QYZ - Z8B C10 H11 Br N8 O3 c1nc(c2c(n....
171 5BVF ic50 = 0.19 nM 4VJ C25 H28 Cl N5 O3 c1cc(cc(c1....
172 6G9M ic50 = 7.9 nM ESW C28 H30 Cl N5 O3 CC(C)(c1cc....
173 6QAH - HVB C3 H9 N2 CCC(=[NH2+....
174 6QA3 - PZO C3 H4 N2 c1c[nH]nc1
175 4XOZ - 620 C15 H16 N6 O c1ccc(cc1)....
176 5HD7 - 38Z C33 H33 N9 O2 c1cnc(nc1)....
177 4XRJ - 620 C15 H16 N6 O c1ccc(cc1)....
178 2OJJ Ki = 0.002 uM 82A C22 H17 Cl2 F N4 O2 c1cc(cc(c1....
179 6Q7K - 2AI C3 H5 N3 c1cnc([nH]....
180 4QTA Kd = 0.233 uM 38Z C33 H33 N9 O2 c1cnc(nc1)....
181 6RQ4 - KE8 C22 H27 N7 O2 S CC1(c2c(cc....
182 5NHO ic50 < 0.0003 uM 8XN C20 H25 N7 O2 Cc1cnc(nc1....
183 2OJG Ki = 2.3 uM 19A C16 H16 N4 O CN(C)C(=O)....
184 3TTI ic50 = 0.006 uM KBI C21 H23 F3 N6 O2 c1c(cc(c(c....
185 3TTJ ic50 = 0.21 uM JBI C23 H23 F N6 O COc1ccc(cc....
186 4H3B Kd = 17.2 uM VAL VAL ARG PRO GLY SER LEU ASP LEU PRO n/a n/a
187 3KVX ic50 = 0.148 uM FMY C26 H27 F N8 O2 c1cc(ccc1/....
188 4H39 Kd = 0.8 uM PRO LYS ARG PRO THR THR LEU ASN LEU PHE n/a n/a
189 4AWI ic50 = 1 uM AQ2 C21 H25 N3 O4 S2 CC(C)c1cc2....
190 2O0U ic50 = 3.2 uM C0M C27 H28 N4 O2 S c1ccc2c(c1....
191 2P33 ic50 = 57 nM J07 C20 H23 Cl N6 O CCNC(=O)N1....
192 2ZDU - 446 C28 H23 Br N2 O6 COC(=O)C1=....
193 2B1P ic50 = 3 nM AIZ C26 H26 Cl N5 O3 CN(C)CCCC(....
194 2OK1 Ki = 0.55 uM 33A C21 H17 Cl N4 O c1ccc(cc1)....
195 3OXI ic50 = 2.2 uM SYY C12 H11 N O3 S2 COC(=O)c1c....
196 3OY1 ic50 = 0.016 uM 589 C28 H31 N5 O2 c1ccc2cc(c....
197 6EMH ic50 = 833 nM BGE C19 H21 N5 O Cc1c([nH]c....
198 2ZDT - 46C C26 H20 Cl N O4 CCC(=O)C1=....
199 3ELJ - GS7 C22 H21 F N6 O4 S COc1cc(ccc....
200 3FI2 ic50 = 0.025 uM JK1 C26 H25 N5 O5 COc1cc(cc(....
201 4L7F ic50 = 160 nM 1V5 C26 H26 F N5 O2 c1cc(ccc1C....
202 6EQ9 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
203 2WAJ ic50 = 0.398 uM SNB C16 H13 Br Cl N O COc1cc2c(c....
204 4QTD ic50 = 1080 nM 38Z C33 H33 N9 O2 c1cnc(nc1)....
205 6EKD ic50 = 184 nM B9K C20 H23 N5 O S Cc1c([nH]c....
206 3G9L Ki = 0.74 uM J67 C25 H19 F N2 O4 c1ccc(cc1)....
207 4Y46 ic50 = 11 nM 4F2 C22 H32 N6 O2 CC(C)NC(=O....
208 1PMN ic50 = 7.1 nM 984 C25 H30 Cl2 N6 CCCn1c(c(n....
209 3FI3 ic50 = 12 nM JK2 C29 H25 F N4 O4 COc1cc(cc(....
210 2O2U ic50 = 0.4 uM 738 C16 H13 F N2 O S c1ccc(c(c1....
211 4W4V ic50 = 866 nM 3H8 C23 H19 Cl N6 O2 Cc1cc(ccn1....
212 3GC8 - B45 C28 H27 Cl3 F N3 O CC(C)N1CCC....
213 5M56 - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
214 5M4U - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
215 6HMD - GDW C21 H24 N2 O2 CCN(CC)CCn....
216 6HMQ - 4B0 C9 H7 Br4 N3 O C(Cn1c2c(c....
217 2PVM Ki = 0.36 uM P29 C17 H15 N9 c1ccc(cc1)....
218 1J91 - TBS C6 H Br4 N3 c12c(c(c(c....
219 3FL5 - TXQ C14 H8 O6 c1cc(c(c2c....
220 3PWD Ki = 0.22 uM CZ0 C14 H9 N O5 CC1=CC(=O)....
221 4ZSL - 4QZ C17 H17 Cl N6 O C[C@@H](c1....
222 6K3L Kd = 60.1 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
223 2F9G - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
224 2B9F - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
225 5AWM - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
226 4EYM - 0RX C21 H20 N4 O3 c1cc(ccc1N....
227 5EKO ic50 = 15785 nM N17 C22 H18 N4 O2 Cc1cn(cn1)....
228 4QTB Kd = 0.213 uM 38Z C33 H33 N9 O2 c1cnc(nc1)....
229 2ZOQ ic50 = 0.9 uM 5ID C11 H13 I N4 O4 c1c(c2c(nc....
230 6GES - EWH C24 H26 Cl N7 O CN1CCN(CC1....
231 3NPC - B96 C31 H37 N5 O3 Cc1ccc(cc1....
232 6XX7 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: YTX; Similar ligands found: 11
No: Ligand ECFP6 Tc MDL keys Tc
1 YTX 1 1
2 DHY 0.511628 0.821429
3 3C4 0.488889 0.7
4 PWK 0.479167 0.666667
5 EOL 0.479167 0.678571
6 LNN 0.433962 0.724138
7 5V6 0.431034 0.69697
8 5UH 0.428571 0.793103
9 VNL 0.408163 0.814815
10 VXX 0.4 0.785714
11 5V5 0.4 0.676471
Similar Ligands (3D)
Ligand no: 1; Ligand: YTX; Similar ligands found: 751
No: Ligand Similarity coefficient
1 NPA 0.9653
2 N7I 0.9595
3 LDP 0.9501
4 6Q3 0.9467
5 9KH 0.9462
6 AEH 0.9457
7 CIY 0.9448
8 3HP 0.9445
9 IAC 0.9438
10 8NB 0.9403
11 42J 0.9399
12 57O 0.9361
13 8U3 0.9361
14 FER 0.9358
15 L99 0.9345
16 B4O 0.9333
17 H7Y 0.9333
18 R20 0.9316
19 LNR 0.9306
20 HQJ 0.9297
21 CXH 0.9287
22 KTW 0.9287
23 OMD 0.9283
24 VM1 0.9279
25 QBM 0.9263
26 ALE 0.9263
27 MPV 0.9260
28 ONR 0.9256
29 263 0.9248
30 F2W 0.9247
31 PRZ 0.9244
32 AX3 0.9243
33 SRO 0.9235
34 0F9 0.9234
35 L5V 0.9225
36 0W1 0.9203
37 APS 0.9200
38 V55 0.9198
39 GO8 0.9186
40 HQ9 0.9186
41 JND 0.9185
42 H4E 0.9178
43 5F5 0.9173
44 RKV 0.9170
45 BZE 0.9168
46 XDE 0.9165
47 TSR 0.9165
48 6DP 0.9162
49 XQI 0.9161
50 DHC 0.9156
51 R1P 0.9152
52 61M 0.9152
53 EUG 0.9151
54 NAG 0.9151
55 AY4 0.9150
56 M1Z 0.9150
57 3R6 0.9150
58 MNP 0.9145
59 428 0.9143
60 IOS 0.9140
61 ZZ2 0.9137
62 6FZ 0.9133
63 LEL 0.9131
64 MQB 0.9127
65 4HP 0.9125
66 ESI 0.9123
67 4SX 0.9121
68 DI6 0.9119
69 15E 0.9119
70 CCV 0.9118
71 BZ2 0.9118
72 8NX 0.9114
73 463 0.9113
74 M4E 0.9108
75 MPP 0.9108
76 NOK 0.9106
77 TSS 0.9105
78 4NC 0.9104
79 GF4 0.9102
80 C9E 0.9102
81 5F8 0.9101
82 ZME 0.9100
83 AC2 0.9096
84 VOH 0.9096
85 HPT 0.9096
86 GC3 0.9092
87 ABF 0.9092
88 LSQ 0.9090
89 BB4 0.9090
90 OW7 0.9089
91 0LO 0.9088
92 ESP 0.9087
93 92P 0.9086
94 ZON 0.9084
95 SAF 0.9084
96 MXD 0.9083
97 NVU 0.9082
98 DAH 0.9081
99 C9M 0.9080
100 BZJ 0.9079
101 L21 0.9076
102 ASC 0.9074
103 BPY 0.9074
104 EYV 0.9073
105 A29 0.9071
106 X0W 0.9071
107 YOF 0.9068
108 P7Y 0.9067
109 069 0.9067
110 TU0 0.9065
111 M3E 0.9063
112 4HM 0.9063
113 M3Q 0.9060
114 TRP 0.9060
115 NFA 0.9055
116 RLG 0.9055
117 PO6 0.9055
118 363 0.9054
119 BIK 0.9054
120 6HP 0.9054
121 M6Z 0.9053
122 NQH 0.9052
123 IHB 0.9052
124 XDK 0.9051
125 2O6 0.9050
126 9FE 0.9050
127 ARP 0.9048
128 5WU 0.9047
129 6J9 0.9044
130 O2A 0.9043
131 NLA 0.9041
132 MMS 0.9038
133 E7S 0.9038
134 0JD 0.9038
135 F31 0.9037
136 HIC 0.9037
137 LYL 0.9037
138 9BF 0.9036
139 K97 0.9036
140 JFJ 0.9034
141 TYL 0.9031
142 KWB 0.9027
143 9ZE 0.9024
144 JP2 0.9024
145 QUS 0.9023
146 TCA 0.9023
147 33S 0.9020
148 N1E 0.9019
149 EXD 0.9019
150 6TZ 0.9018
151 3VX 0.9017
152 R9Y 0.9015
153 QSB 0.9015
154 CFA 0.9015
155 KW8 0.9014
156 ICB 0.9013
157 FA1 0.9011
158 XEN 0.9010
159 GJK 0.9007
160 QMS 0.9006
161 60L 0.9006
162 P9P 0.9005
163 B41 0.9004
164 IYR 0.9001
165 X48 0.9001
166 L22 0.9000
167 KTA 0.8999
168 GNM 0.8997
169 GZ2 0.8995
170 3Y7 0.8993
171 F0J 0.8992
172 5TZ 0.8992
173 AH8 0.8991
174 14W 0.8990
175 FK8 0.8989
176 E35 0.8989
177 PHE 0.8988
178 TNX 0.8987
179 TZM 0.8985
180 F52 0.8981
181 EV0 0.8981
182 HA5 0.8978
183 15N 0.8978
184 4ME 0.8977
185 DNF 0.8976
186 NBG 0.8975
187 FF2 0.8974
188 HJH 0.8974
189 X0V 0.8971
190 N91 0.8971
191 NIY 0.8971
192 4M4 0.8971
193 XCG 0.8970
194 4FF 0.8968
195 DHB 0.8966
196 0HO 0.8965
197 7MU 0.8964
198 RP5 0.8964
199 M02 0.8962
200 790 0.8960
201 Y3L 0.8959
202 GO2 0.8959
203 4XF 0.8959
204 RP3 0.8957
205 TYR 0.8957
206 4BY 0.8957
207 DEW 0.8952
208 V1T 0.8951
209 FWD 0.8950
210 BK9 0.8948
211 AS3 0.8947
212 1M2 0.8946
213 JF1 0.8944
214 GZL 0.8944
215 XIY 0.8942
216 0LH 0.8941
217 AH9 0.8941
218 LL1 0.8941
219 8WT 0.8941
220 EWG 0.8940
221 4V2 0.8940
222 DHK 0.8940
223 8GK 0.8939
224 3ZB 0.8939
225 692 0.8939
226 PPY 0.8939
227 93K 0.8937
228 RD4 0.8929
229 AAN 0.8928
230 KOJ 0.8928
231 XIZ 0.8927
232 ANC 0.8926
233 SBK 0.8926
234 SOR 0.8926
235 2AL 0.8925
236 JAW 0.8925
237 N2M 0.8925
238 JDN 0.8922
239 CHB 0.8920
240 TWO 0.8919
241 DHS 0.8919
242 BCU 0.8918
243 CWD 0.8917
244 J6W 0.8916
245 4FH 0.8916
246 AEG 0.8915
247 6NT 0.8915
248 XX2 0.8913
249 K3Q 0.8912
250 2HC 0.8910
251 G1P 0.8910
252 5OF 0.8909
253 CKU 0.8908
254 INO 0.8906
255 0FK 0.8906
256 V2Z 0.8906
257 4BL 0.8906
258 6QF 0.8906
259 KYA 0.8904
260 AVA 0.8904
261 CSN 0.8903
262 C2Y 0.8902
263 P80 0.8902
264 HCI 0.8901
265 SYE 0.8897
266 2BG 0.8893
267 3IL 0.8892
268 EMZ 0.8891
269 4R1 0.8890
270 OX2 0.8889
271 2FX 0.8888
272 M5E 0.8888
273 F4E 0.8884
274 8ZE 0.8883
275 2D2 0.8882
276 4XV 0.8882
277 N2I 0.8882
278 BG6 0.8880
279 G6P 0.8880
280 795 0.8879
281 NDG 0.8879
282 EGR 0.8878
283 TR4 0.8877
284 JG8 0.8877
285 6RQ 0.8876
286 IOP 0.8874
287 3C5 0.8873
288 BNL 0.8873
289 GJP 0.8872
290 1KP 0.8870
291 CH9 0.8870
292 X6P 0.8870
293 1F1 0.8870
294 IWD 0.8868
295 TYE 0.8867
296 TA6 0.8867
297 2ZM 0.8864
298 9TW 0.8864
299 NGT 0.8863
300 ESX 0.8863
301 NGW 0.8863
302 FUD 0.8862
303 2LT 0.8860
304 5E5 0.8860
305 UNJ 0.8860
306 DOR 0.8859
307 PLP 0.8858
308 DNC 0.8858
309 78Y 0.8858
310 KDV 0.8857
311 YO5 0.8857
312 MN9 0.8857
313 M5H 0.8856
314 9UL 0.8856
315 1A7 0.8855
316 BQ2 0.8855
317 AMR 0.8853
318 BWD 0.8852
319 36E 0.8852
320 HNK 0.8852
321 5JT 0.8851
322 4XS 0.8851
323 8XL 0.8851
324 EDR 0.8850
325 IQ5 0.8850
326 SLS 0.8849
327 ZRK 0.8849
328 ABI 0.8848
329 SG2 0.8847
330 HSX 0.8847
331 7I2 0.8846
332 PSJ 0.8844
333 8W9 0.8844
334 DXP 0.8844
335 55D 0.8844
336 DTE 0.8843
337 ZYQ 0.8843
338 4I8 0.8842
339 NFM 0.8842
340 TMG 0.8842
341 F6P 0.8842
342 KJU 0.8841
343 R9G 0.8841
344 GLP 0.8840
345 F1X 0.8840
346 TT4 0.8840
347 8G6 0.8838
348 S7S 0.8838
349 NYL 0.8837
350 ZHA 0.8837
351 STT 0.8835
352 MSR 0.8834
353 QH3 0.8833
354 12T 0.8833
355 X0U 0.8832
356 5NI 0.8832
357 CLU 0.8831
358 GC2 0.8830
359 SNU 0.8828
360 NIG 0.8827
361 JZ4 0.8827
362 MD6 0.8825
363 HBO 0.8825
364 LPK 0.8825
365 UFO 0.8824
366 M4T 0.8823
367 D3G 0.8823
368 7WR 0.8823
369 3QV 0.8822
370 C82 0.8822
371 0HN 0.8820
372 CTE 0.8820
373 YZM 0.8819
374 2EC 0.8819
375 PDC 0.8819
376 MR1 0.8817
377 RVE 0.8817
378 344 0.8816
379 4WL 0.8816
380 4P5 0.8815
381 FRU 0.8814
382 EKZ 0.8814
383 3PF 0.8814
384 ITE 0.8813
385 2JK 0.8811
386 GV9 0.8810
387 JR2 0.8809
388 K80 0.8809
389 IPT 0.8808
390 6NZ 0.8808
391 78U 0.8807
392 QIV 0.8807
393 SR1 0.8807
394 B2J 0.8807
395 PH3 0.8807
396 J0Z 0.8806
397 W8G 0.8806
398 3NY 0.8805
399 MP5 0.8804
400 67Y 0.8802
401 MUK 0.8802
402 3A9 0.8800
403 C0W 0.8799
404 3EB 0.8798
405 QSH 0.8798
406 A5E 0.8797
407 5GT 0.8795
408 TAG 0.8794
409 4FE 0.8793
410 8WO 0.8793
411 3RI 0.8792
412 DTR 0.8792
413 EVF 0.8791
414 U7E 0.8791
415 2DL 0.8789
416 M3P 0.8789
417 RNO 0.8788
418 NCV 0.8788
419 SOV 0.8787
420 NGO 0.8787
421 4AV 0.8787
422 HRM 0.8787
423 MUR 0.8786
424 IFG 0.8785
425 492 0.8784
426 9FL 0.8783
427 BGC 0.8782
428 YRL 0.8781
429 AOT 0.8779
430 JTH 0.8779
431 2KU 0.8777
432 WUB 0.8776
433 CR1 0.8776
434 3YP 0.8775
435 2HO 0.8775
436 P84 0.8775
437 5B2 0.8774
438 PZI 0.8772
439 45L 0.8771
440 DEE 0.8770
441 NCT 0.8767
442 GDE 0.8767
443 9GP 0.8767
444 5TY 0.8766
445 0NX 0.8766
446 GRX 0.8766
447 K7M 0.8766
448 S7G 0.8765
449 SKM 0.8765
450 PJW 0.8764
451 GRF 0.8764
452 JTA 0.8763
453 2BX 0.8763
454 HHH 0.8763
455 M78 0.8760
456 SNO 0.8760
457 GDL 0.8760
458 SQV 0.8759
459 7VP 0.8759
460 36Y 0.8758
461 BGU 0.8757
462 LFQ 0.8757
463 PLR 0.8756
464 GCO 0.8756
465 M3H 0.8756
466 9F8 0.8754
467 IWT 0.8754
468 54X 0.8750
469 BY5 0.8750
470 LQ2 0.8749
471 4FA 0.8749
472 AN3 0.8749
473 CK1 0.8749
474 S60 0.8749
475 268 0.8748
476 4A5 0.8748
477 CPZ 0.8747
478 5OO 0.8747
479 CKA 0.8745
480 DXK 0.8744
481 4ZA 0.8743
482 0SY 0.8743
483 FLC 0.8743
484 MYJ 0.8742
485 1L5 0.8742
486 F9Y 0.8742
487 2V0 0.8741
488 EN1 0.8740
489 DK1 0.8739
490 B40 0.8739
491 JCZ 0.8737
492 HDH 0.8736
493 J9T 0.8734
494 HL4 0.8733
495 5WT 0.8733
496 IL5 0.8732
497 4MU 0.8732
498 717 0.8731
499 5RO 0.8731
500 A5H 0.8731
501 1VK 0.8730
502 2HU 0.8728
503 1ZC 0.8728
504 4A3 0.8727
505 0BP 0.8726
506 FHB 0.8726
507 5XC 0.8726
508 MQG 0.8726
509 SZ7 0.8724
510 BNF 0.8723
511 G4D 0.8721
512 BDP 0.8720
513 MAJ 0.8720
514 4VY 0.8720
515 4XY 0.8720
516 7O4 0.8719
517 PRY 0.8719
518 7ME 0.8718
519 PBA 0.8718
520 30G 0.8717
521 HIS 0.8716
522 ALN 0.8716
523 BSX 0.8716
524 ES2 0.8715
525 HNE 0.8715
526 505 0.8712
527 DCZ 0.8711
528 F06 0.8711
529 5GU 0.8710
530 X11 0.8710
531 ENO 0.8710
532 SYR 0.8709
533 RBJ 0.8709
534 HXY 0.8708
535 27B 0.8706
536 B85 0.8705
537 YPN 0.8704
538 7ZL 0.8703
539 68A 0.8703
540 MTL 0.8703
541 CK2 0.8702
542 S3C 0.8701
543 5WN 0.8700
544 NNO 0.8700
545 I2E 0.8699
546 SDD 0.8699
547 OW4 0.8699
548 ALX 0.8696
549 DIN 0.8694
550 J9N 0.8694
551 T6Z 0.8692
552 3BU 0.8691
553 8HC 0.8691
554 PBN 0.8690
555 CNI 0.8690
556 GNY 0.8689
557 M6P 0.8689
558 2CZ 0.8688
559 FGZ 0.8688
560 J5I 0.8688
561 S2G 0.8688
562 293 0.8687
563 4OG 0.8687
564 BM3 0.8687
565 4PN 0.8686
566 MRW 0.8685
567 ZXD 0.8685
568 PD2 0.8685
569 8TX 0.8684
570 MB1 0.8684
571 SQ7 0.8684
572 6R8 0.8684
573 0XT 0.8683
574 F12 0.8682
575 6KT 0.8682
576 FWB 0.8682
577 DLT 0.8682
578 I59 0.8682
579 JRB 0.8682
580 97T 0.8681
581 6NI 0.8681
582 2FQ 0.8681
583 DRG 0.8679
584 259 0.8678
585 AEF 0.8678
586 1Z8 0.8677
587 PH2 0.8676
588 CXP 0.8676
589 A7W 0.8676
590 KF5 0.8676
591 GFP 0.8675
592 GLO 0.8674
593 NGA 0.8672
594 GAL 0.8672
595 2GQ 0.8672
596 P81 0.8671
597 IPD 0.8671
598 2D3 0.8670
599 W81 0.8670
600 PQK 0.8668
601 RQD 0.8668
602 MVH 0.8664
603 SKF 0.8664
604 4TP 0.8664
605 REL 0.8664
606 HNL 0.8661
607 173 0.8661
608 6FB 0.8661
609 F5C 0.8660
610 KLV 0.8660
611 FIX 0.8660
612 AJY 0.8659
613 HFA 0.8658
614 HX3 0.8658
615 3MG 0.8658
616 HQD 0.8658
617 HC4 0.8657
618 4GP 0.8657
619 HX4 0.8656
620 FQX 0.8655
621 3DO 0.8654
622 BPU 0.8652
623 N9J 0.8652
624 5QY 0.8651
625 1AL 0.8651
626 GNV 0.8651
627 JB8 0.8650
628 XFE 0.8649
629 HPS 0.8646
630 GHM 0.8645
631 2UD 0.8645
632 1SS 0.8645
633 GCU 0.8644
634 4TU 0.8644
635 6HO 0.8644
636 3J8 0.8644
637 0A9 0.8642
638 BRH 0.8642
639 GNL 0.8642
640 GVG 0.8641
641 DPN 0.8640
642 3HM 0.8640
643 FHC 0.8640
644 KYN 0.8640
645 MMN 0.8639
646 PRA 0.8638
647 D48 0.8638
648 LTN 0.8638
649 NWD 0.8637
650 DA4 0.8637
651 4BZ 0.8636
652 BZ3 0.8636
653 OTR 0.8636
654 9PL 0.8635
655 1IT 0.8634
656 P4L 0.8634
657 I4D 0.8633
658 NIR 0.8632
659 9CA 0.8632
660 AOR 0.8631
661 PQ0 0.8630
662 AMQ 0.8629
663 DGJ 0.8629
664 2UZ 0.8628
665 4LW 0.8628
666 LIP 0.8626
667 264 0.8626
668 GLC 0.8625
669 HBI 0.8624
670 PPT 0.8623
671 5OB 0.8622
672 6VD 0.8622
673 ARG 0.8616
674 5RP 0.8615
675 EYJ 0.8615
676 3LJ 0.8614
677 9R5 0.8613
678 URC 0.8613
679 S8V 0.8613
680 O2Y 0.8612
681 657 0.8612
682 TXW 0.8611
683 209 0.8610
684 J9Q 0.8610
685 A9O 0.8610
686 7R4 0.8610
687 BGP 0.8609
688 1HN 0.8609
689 5LA 0.8608
690 G3E 0.8608
691 S0D 0.8608
692 BIO 0.8607
693 JLZ 0.8607
694 7MK 0.8606
695 PMP 0.8606
696 PVQ 0.8605
697 3VW 0.8605
698 OSB 0.8604
699 GLN 0.8604
700 LRW 0.8603
701 549 0.8603
702 PIY 0.8603
703 DTY 0.8601
704 1SV 0.8601
705 GAB 0.8600
706 EV2 0.8600
707 8IG 0.8599
708 CGW 0.8598
709 SE2 0.8597
710 N2Z 0.8594
711 A5P 0.8593
712 DNA 0.8590
713 CPW 0.8590
714 SSY 0.8590
715 ZZA 0.8590
716 PVK 0.8588
717 QBS 0.8587
718 977 0.8582
719 8G0 0.8581
720 MIL 0.8580
721 PNZ 0.8579
722 K3Y 0.8579
723 FZM 0.8576
724 SHA 0.8575
725 0N7 0.8575
726 1X8 0.8572
727 ETV 0.8572
728 1P8 0.8572
729 KUF 0.8570
730 GGL 0.8570
731 49P 0.8569
732 ZIQ 0.8568
733 MBG 0.8568
734 CN0 0.8564
735 OUB 0.8564
736 WCE 0.8564
737 KMH 0.8561
738 ASO 0.8561
739 UA5 0.8551
740 5RN 0.8550
741 CC5 0.8549
742 B55 0.8543
743 1Z6 0.8538
744 ZEC 0.8537
745 QMP 0.8535
746 3HB 0.8530
747 BPW 0.8530
748 4BF 0.8530
749 GXL 0.8527
750 LYS 0.8525
751 KG1 0.8512
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5H8E; Ligand: 5Y3; Similar sites found with APoc: 17
This union binding pocket(no: 1) in the query (biounit: 5h8e.bio2) has 60 residues
No: Leader PDB Ligand Sequence Similarity
1 4OH4 ANP 12.6126
2 4OH4 ANP 12.6126
3 3SRV S19 22.5225
4 3SRV S19 22.5225
5 3UIM ANP 27.6276
6 6JKM ADP 28.8288
7 6PJX SGV 36.9369
8 4UX9 ANP 44.4444
9 4UX9 ANP 44.4444
10 6FYV 3NG 45.6456
11 1Q8Y ADE 46.5465
12 4H3P ANP 46.5465
13 6K0J CQO 47.1471
14 5ZTN CUR 47.4474
15 5ZTN CUR 47.4474